Mus musculus

0 known processes

Ndufa4

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4

(Aliases: MLRQ)

Ndufa4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.596
atp metabolic process GO:0046034 75 0.458
nucleoside triphosphate metabolic process GO:0009141 230 0.448
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.418
purine ribonucleoside metabolic process GO:0046128 241 0.394
ribonucleotide metabolic process GO:0009259 291 0.383
nucleoside metabolic process GO:0009116 246 0.333
purine nucleoside metabolic process GO:0042278 241 0.311
nucleoside phosphate metabolic process GO:0006753 338 0.307
nucleoside monophosphate metabolic process GO:0009123 85 0.305
glycosyl compound metabolic process GO:1901657 246 0.302
purine containing compound metabolic process GO:0072521 311 0.275
ribonucleoside triphosphate metabolic process GO:0009199 220 0.264
nucleobase containing small molecule metabolic process GO:0055086 352 0.249
purine nucleotide metabolic process GO:0006163 302 0.248
purine nucleoside monophosphate catabolic process GO:0009128 58 0.235
purine nucleoside monophosphate metabolic process GO:0009126 81 0.193
nucleotide metabolic process GO:0009117 332 0.192
transmembrane transport GO:0055085 412 0.184
carbohydrate derivative catabolic process GO:1901136 231 0.168
purine nucleoside triphosphate metabolic process GO:0009144 226 0.153
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.149
ribonucleoside monophosphate metabolic process GO:0009161 80 0.144
aromatic compound catabolic process GO:0019439 286 0.141
purine ribonucleotide metabolic process GO:0009150 290 0.140
ribonucleotide catabolic process GO:0009261 208 0.134
nucleoside triphosphate catabolic process GO:0009143 205 0.127
ribose phosphate metabolic process GO:0019693 291 0.119
nucleoside catabolic process GO:0009164 206 0.114
energy derivation by oxidation of organic compounds GO:0015980 77 0.112
atp catabolic process GO:0006200 55 0.111
purine ribonucleotide catabolic process GO:0009154 208 0.104
cellular respiration GO:0045333 38 0.103
ribonucleoside triphosphate catabolic process GO:0009203 199 0.098
ribonucleoside monophosphate catabolic process GO:0009158 57 0.093
purine containing compound catabolic process GO:0072523 213 0.078
nucleoside monophosphate catabolic process GO:0009125 59 0.077
intracellular protein transport GO:0006886 204 0.071
ribonucleoside catabolic process GO:0042454 206 0.067
nucleotide catabolic process GO:0009166 217 0.065
ion transmembrane transport GO:0034220 361 0.064
purine nucleoside catabolic process GO:0006152 205 0.060
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.058
cytoplasmic transport GO:0016482 234 0.057
negative regulation of cell proliferation GO:0008285 296 0.052
glycosyl compound catabolic process GO:1901658 206 0.051
nucleoside phosphate catabolic process GO:1901292 222 0.051
organophosphate catabolic process GO:0046434 232 0.048
organonitrogen compound catabolic process GO:1901565 264 0.045
purine nucleotide catabolic process GO:0006195 211 0.042
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.041
protein maturation GO:0051604 176 0.040
organic cyclic compound catabolic process GO:1901361 295 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.037
establishment of protein localization to organelle GO:0072594 118 0.036
cation transport GO:0006812 399 0.036
positive regulation of mapk cascade GO:0043410 170 0.034
endocytosis GO:0006897 168 0.034
cation transmembrane transport GO:0098655 266 0.032
regulation of kinase activity GO:0043549 249 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
negative regulation of organelle organization GO:0010639 90 0.032
protein localization to organelle GO:0033365 185 0.032
mitochondrial transport GO:0006839 36 0.031
regulation of body fluid levels GO:0050878 162 0.030
apoptotic signaling pathway GO:0097190 306 0.030
regulation of mapk cascade GO:0043408 248 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.029
inorganic ion transmembrane transport GO:0098660 234 0.029
myeloid cell differentiation GO:0030099 233 0.029
negative regulation of cellular component organization GO:0051129 194 0.027
protein processing GO:0016485 163 0.027
regulation of establishment of protein localization GO:0070201 181 0.026
microtubule cytoskeleton organization GO:0000226 157 0.026
cellular response to molecule of bacterial origin GO:0071219 83 0.026
substantia nigra development GO:0021762 2 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
regulation of nucleocytoplasmic transport GO:0046822 73 0.024
cellular response to lipid GO:0071396 145 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
nitrogen compound transport GO:0071705 271 0.023
mitochondrion organization GO:0007005 134 0.023
reactive oxygen species metabolic process GO:0072593 84 0.023
protein import into nucleus GO:0006606 95 0.022
generation of precursor metabolites and energy GO:0006091 103 0.022
extrinsic apoptotic signaling pathway GO:0097191 126 0.022
positive regulation of transferase activity GO:0051347 167 0.022
spermatogenesis GO:0007283 284 0.022
placenta development GO:0001890 140 0.022
cell type specific apoptotic process GO:0097285 268 0.022
cellular response to oxidative stress GO:0034599 76 0.021
muscle contraction GO:0006936 101 0.021
regulation of protein localization GO:0032880 231 0.021
leukocyte differentiation GO:0002521 342 0.021
cognition GO:0050890 149 0.021
mapk cascade GO:0000165 281 0.021
protein targeting GO:0006605 143 0.021
myeloid cell homeostasis GO:0002262 114 0.020
microtubule based process GO:0007017 236 0.020
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
protein import GO:0017038 101 0.019
male gamete generation GO:0048232 285 0.019
wound healing GO:0042060 157 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
lymphocyte differentiation GO:0030098 242 0.018
determination of adult lifespan GO:0008340 11 0.018
learning or memory GO:0007611 148 0.018
multicellular organismal aging GO:0010259 24 0.018
amide transport GO:0042886 138 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
positive regulation of kinase activity GO:0033674 155 0.017
regulation of protein kinase activity GO:0045859 232 0.017
positive regulation of protein modification process GO:0031401 299 0.017
multi multicellular organism process GO:0044706 109 0.016
nuclear import GO:0051170 95 0.016
regulation of hydrolase activity GO:0051336 246 0.016
innate immune response GO:0045087 157 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
negative regulation of leukocyte differentiation GO:1902106 51 0.016
membrane organization GO:0061024 245 0.016
response to organic cyclic compound GO:0014070 198 0.016
gonad development GO:0008406 141 0.016
regulation of secretion GO:0051046 274 0.016
inflammatory response GO:0006954 244 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
negative regulation of molecular function GO:0044092 258 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.014
response to lipopolysaccharide GO:0032496 128 0.014
cellular ion homeostasis GO:0006873 165 0.014
homeostasis of number of cells GO:0048872 210 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
nuclear transport GO:0051169 139 0.014
regulation of response to wounding GO:1903034 189 0.014
regulation of cell activation GO:0050865 289 0.014
regulation of intracellular transport GO:0032386 159 0.014
cellular ketone metabolic process GO:0042180 84 0.014
heterocycle catabolic process GO:0046700 280 0.014
regulation of organelle organization GO:0033043 289 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
cellular protein complex assembly GO:0043623 116 0.014
extracellular structure organization GO:0043062 148 0.013
hydrogen ion transmembrane transport GO:1902600 25 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
regulation of peptidase activity GO:0052547 96 0.013
leukocyte proliferation GO:0070661 172 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
cellular lipid metabolic process GO:0044255 323 0.013
protein localization to membrane GO:0072657 108 0.013
response to oxygen levels GO:0070482 62 0.013
carboxylic acid transport GO:0046942 100 0.013
peptide transport GO:0015833 133 0.013
epithelial cell proliferation GO:0050673 174 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
development of primary sexual characteristics GO:0045137 143 0.013
zymogen activation GO:0031638 41 0.013
anion transport GO:0006820 177 0.013
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.012
neuron death GO:0070997 154 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
4 hydroxyproline metabolic process GO:0019471 5 0.012
regulation of protein targeting GO:1903533 61 0.012
amine metabolic process GO:0009308 45 0.012
regulation of cellular ketone metabolic process GO:0010565 66 0.012
regulation of proteolysis GO:0030162 164 0.012
dna metabolic process GO:0006259 303 0.012
locomotory behavior GO:0007626 195 0.012
cellular amino acid metabolic process GO:0006520 103 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
regulation of t cell activation GO:0050863 170 0.012
neuron apoptotic process GO:0051402 142 0.012
adult behavior GO:0030534 135 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
regulation of neuron differentiation GO:0045664 281 0.012
regulation of protein transport GO:0051223 163 0.012
single organism nuclear import GO:1902593 95 0.012
synaptic transmission GO:0007268 329 0.011
regulation of cellular response to stress GO:0080135 159 0.011
cellular homeostasis GO:0019725 240 0.011
negative regulation of t cell activation GO:0050868 65 0.011
regulation of neuron death GO:1901214 134 0.011
signal transduction in absence of ligand GO:0038034 55 0.011
positive regulation of camp mediated signaling GO:0043950 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
t cell activation GO:0042110 289 0.011
regulation of ion transport GO:0043269 215 0.011
chemotaxis GO:0006935 247 0.011
lymphocyte proliferation GO:0046651 164 0.011
epidermis development GO:0008544 187 0.011
response to radiation GO:0009314 165 0.010
thymus development GO:0048538 41 0.010
response to hypoxia GO:0001666 58 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
regulation of transferase activity GO:0051338 263 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
skin development GO:0043588 220 0.010
regulation of secretion by cell GO:1903530 249 0.010

Ndufa4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.032
disease of anatomical entity DOID:7 0 0.032
disease of metabolism DOID:0014667 0 0.028
inherited metabolic disorder DOID:655 0 0.028