Mus musculus

570 known processes

Nf1

neurofibromatosis 1

(Aliases: E030030H24Rik,Nf-1,AW494271)

Nf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of glial cell proliferation GO:0060253 4 0.994
gliogenesis GO:0042063 141 0.991
t cell activation GO:0042110 289 0.991
leukocyte differentiation GO:0002521 342 0.990
regulation of hippo signaling GO:0035330 1 0.989
leukocyte proliferation GO:0070661 172 0.988
muscle cell differentiation GO:0042692 261 0.987
small gtpase mediated signal transduction GO:0007264 97 0.984
negative regulation of epithelial cell proliferation GO:0050680 64 0.983
oocyte construction GO:0007308 2 0.981
regulation of protein stability GO:0031647 52 0.974
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.974
ras protein signal transduction GO:0007265 77 0.972
negative regulation of leukocyte differentiation GO:1902106 51 0.971
epithelial tube morphogenesis GO:0060562 303 0.971
epithelial cell proliferation GO:0050673 174 0.969
organic cyclic compound catabolic process GO:1901361 295 0.968
lymphocyte differentiation GO:0030098 242 0.968
oocyte differentiation GO:0009994 35 0.966
cellular response to growth factor stimulus GO:0071363 197 0.966
ribonucleotide metabolic process GO:0009259 291 0.965
stem cell maintenance GO:0019827 130 0.963
regulation of kinase activity GO:0043549 249 0.955
oocyte axis specification GO:0007309 2 0.954
gtp catabolic process GO:0006184 143 0.953
positive regulation of ras gtpase activity GO:0032320 65 0.953
male gamete generation GO:0048232 285 0.949
regionalization GO:0003002 337 0.945
negative regulation of t cell proliferation GO:0042130 38 0.941
guanosine containing compound metabolic process GO:1901068 144 0.937
myotube differentiation GO:0014902 105 0.937
cardiac muscle cell differentiation GO:0055007 69 0.935
insulin secretion GO:0030073 89 0.934
hormone secretion GO:0046879 128 0.927
negative regulation of molecular function GO:0044092 258 0.927
ribonucleoside catabolic process GO:0042454 206 0.926
germ cell development GO:0007281 185 0.924
mapk cascade GO:0000165 281 0.921
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.919
branching morphogenesis of an epithelial tube GO:0048754 159 0.919
ribonucleotide catabolic process GO:0009261 208 0.918
cardiac endothelial cell differentiation GO:0003348 4 0.918
nitrogen compound transport GO:0071705 271 0.917
cell growth GO:0016049 130 0.916
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.915
rho protein signal transduction GO:0007266 32 0.912
negative regulation of fibroblast migration GO:0010764 2 0.909
atrial septum primum morphogenesis GO:0003289 3 0.907
erk1 and erk2 cascade GO:0070371 77 0.906
Zebrafish
ribonucleoside triphosphate catabolic process GO:0009203 199 0.905
regulation of rho gtpase activity GO:0032319 58 0.904
positive regulation of rho gtpase activity GO:0032321 41 0.904
positive regulation of glial cell proliferation GO:0060252 4 0.901
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.901
regulation of leukocyte differentiation GO:1902105 159 0.900
positive regulation of neuron differentiation GO:0045666 141 0.899
regulation of transferase activity GO:0051338 263 0.898
positive regulation of apoptotic signaling pathway GO:2001235 95 0.894
regulation of purine nucleotide catabolic process GO:0033121 122 0.893
cell adhesion GO:0007155 329 0.892
neuron apoptotic process GO:0051402 142 0.890
glycosyl compound metabolic process GO:1901657 246 0.889
neuron death GO:0070997 154 0.887
wound healing GO:0042060 157 0.886
formation of radial glial scaffolds GO:0021943 4 0.885
stem cell development GO:0048864 219 0.884
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.883
positive regulation of nucleoside metabolic process GO:0045979 91 0.883
ureteric bud development GO:0001657 94 0.882
carbohydrate derivative catabolic process GO:1901136 231 0.880
regulation of cellular catabolic process GO:0031329 242 0.874
development of primary sexual characteristics GO:0045137 143 0.873
actin filament organization GO:0007015 113 0.873
negative regulation of synaptic vesicle transport GO:1902804 3 0.871
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.870
organonitrogen compound catabolic process GO:1901565 264 0.868
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.868
negative regulation of cell proliferation GO:0008285 296 0.867
negative regulation of lymphocyte activation GO:0051250 91 0.865
purine nucleoside metabolic process GO:0042278 241 0.864
epidermal growth factor receptor signaling pathway GO:0007173 28 0.863
endodermal cell fate determination GO:0007493 2 0.862
forebrain development GO:0030900 302 0.860
positive regulation of protein phosphorylation GO:0001934 242 0.856
purine ribonucleoside catabolic process GO:0046130 205 0.855
g1 s transition of mitotic cell cycle GO:0000082 57 0.855
mesenchyme development GO:0060485 152 0.855
peptide transport GO:0015833 133 0.855
negative regulation of neuron death GO:1901215 98 0.853
learning GO:0007612 98 0.852
cell type specific apoptotic process GO:0097285 268 0.850
ossification GO:0001503 216 0.847
negative regulation of gliogenesis GO:0014014 23 0.845
nucleoside phosphate catabolic process GO:1901292 222 0.845
regulation of rho protein signal transduction GO:0035023 71 0.844
spermatid differentiation GO:0048515 115 0.843
response to organonitrogen compound GO:0010243 246 0.839
single organism cell adhesion GO:0098602 156 0.838
embryonic organ morphogenesis GO:0048562 276 0.835
regulation of lymphocyte proliferation GO:0050670 117 0.834
neurotrophin trk receptor signaling pathway GO:0048011 8 0.831
regulation of wound healing GO:0061041 40 0.828
glial cell development GO:0021782 54 0.825
cellular nitrogen compound catabolic process GO:0044270 280 0.824
stem cell differentiation GO:0048863 268 0.821
organ growth GO:0035265 117 0.817
negative regulation of phosphorylation GO:0042326 166 0.816
negative regulation of protein phosphorylation GO:0001933 126 0.813
protein catabolic process GO:0030163 221 0.812
regulation of ras protein signal transduction GO:0046578 114 0.811
positive regulation of cell death GO:0010942 224 0.810
regulation of t cell differentiation GO:0045580 83 0.809
regulation of cell migration GO:0030334 219 0.808
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.803
response to growth factor GO:0070848 198 0.802
telencephalon development GO:0021537 186 0.800
associative learning GO:0008306 61 0.795
regulation of hormone secretion GO:0046883 88 0.795
positive regulation of growth GO:0045927 104 0.794
Fly
positive regulation of nervous system development GO:0051962 221 0.793
heterocycle catabolic process GO:0046700 280 0.792
endodermal cell fate specification GO:0001714 4 0.791
regulation of hormone levels GO:0010817 211 0.790
regulation of cellular component biogenesis GO:0044087 181 0.783
Fly
myeloid cell differentiation GO:0030099 233 0.783
innate immune response GO:0045087 157 0.783
regulation of cell activation GO:0050865 289 0.779
peptide secretion GO:0002790 114 0.778
sertoli cell differentiation GO:0060008 18 0.777
rhythmic process GO:0048511 174 0.774
Fly
cellular response to lipid GO:0071396 145 0.773
positive regulation of secretion GO:0051047 130 0.770
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.770
regulation of cytoskeleton organization GO:0051493 122 0.770
purine nucleoside catabolic process GO:0006152 205 0.764
regulation of nucleoside metabolic process GO:0009118 130 0.761
ribonucleoside metabolic process GO:0009119 245 0.761
striated muscle tissue development GO:0014706 293 0.760
negative regulation of lymphocyte proliferation GO:0050672 45 0.757
urogenital system development GO:0001655 261 0.755
chondrocyte hypertrophy GO:0003415 4 0.754
positive regulation of apoptotic process GO:0043065 217 0.750
t cell proliferation GO:0042098 120 0.750
negative regulation of cell cycle phase transition GO:1901988 48 0.749
cellular ketone metabolic process GO:0042180 84 0.748
mesonephros development GO:0001823 97 0.747
morphogenesis of a branching epithelium GO:0061138 193 0.747
positive regulation of nucleotide catabolic process GO:0030813 88 0.746
regulation of peptide secretion GO:0002791 77 0.744
regulation of cell adhesion GO:0030155 154 0.743
endodermal cell fate commitment GO:0001711 12 0.742
negative regulation of protein modification process GO:0031400 163 0.740
multicellular organismal signaling GO:0035637 91 0.737
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.735
regulation of peptide transport GO:0090087 91 0.734
striated muscle cell development GO:0055002 125 0.734
response to insulin GO:0032868 100 0.734
regulation of secretion GO:0051046 274 0.731
regulation of cell cycle GO:0051726 281 0.730
morphogenesis of a branching structure GO:0001763 203 0.728
regulation of insulin receptor signaling pathway GO:0046626 21 0.728
regulation of nucleotide catabolic process GO:0030811 122 0.726
positive regulation of gtp catabolic process GO:0033126 85 0.726
regulation of nucleotide metabolic process GO:0006140 169 0.725
regulation of lens epithelial cell proliferation GO:2001109 1 0.718
gland development GO:0048732 330 0.715
nephron tubule morphogenesis GO:0072078 68 0.714
ureteric bud morphogenesis GO:0060675 62 0.714
negative regulation of mitotic cell cycle GO:0045930 58 0.714
glial cell proliferation GO:0014009 10 0.712
Zebrafish
blood vessel morphogenesis GO:0048514 285 0.711
embryonic skeletal system morphogenesis GO:0048704 91 0.711
neural crest cell migration GO:0001755 32 0.708
nucleoside catabolic process GO:0009164 206 0.706
cell cycle checkpoint GO:0000075 47 0.703
extrinsic apoptotic signaling pathway GO:0097191 126 0.702
axon ensheathment GO:0008366 76 0.701
positive regulation of protein modification process GO:0031401 299 0.701
endocardial cell differentiation GO:0060956 4 0.700
cellular response to external stimulus GO:0071496 88 0.700
regulation of protein kinase activity GO:0045859 232 0.700
nucleocytoplasmic transport GO:0006913 139 0.700
eye photoreceptor cell differentiation GO:0001754 41 0.696
fat cell differentiation GO:0045444 160 0.696
amide transport GO:0042886 138 0.695
ureter morphogenesis GO:0072197 4 0.695
neural crest cell development GO:0014032 48 0.693
primary prostatic bud elongation GO:0060516 2 0.691
positive regulation of gtpase activity GO:0043547 85 0.690
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.690
actin cytoskeleton organization GO:0030036 220 0.690
regulation of nucleocytoplasmic transport GO:0046822 73 0.689
protein localization to nucleus GO:0034504 121 0.686
macroautophagy GO:0016236 21 0.682
negative regulation of t cell activation GO:0050868 65 0.680
smooth muscle tissue development GO:0048745 22 0.679
negative regulation of leukocyte proliferation GO:0070664 46 0.679
purine nucleotide catabolic process GO:0006195 211 0.678
neuronal action potential GO:0019228 54 0.677
positive regulation of peptide hormone secretion GO:0090277 31 0.677
cellular response to dna damage stimulus GO:0006974 207 0.675
negative regulation of phosphate metabolic process GO:0045936 184 0.674
regulation of t cell activation GO:0050863 170 0.674
positive regulation of cell migration GO:0030335 109 0.671
single organismal cell cell adhesion GO:0016337 131 0.671
positive regulation of mapk cascade GO:0043410 170 0.668
positive regulation of insulin secretion GO:0032024 26 0.667
regulation of gliogenesis GO:0014013 50 0.667
response to extracellular stimulus GO:0009991 127 0.667
developmental maturation GO:0021700 193 0.667
regulation of protein serine threonine kinase activity GO:0071900 157 0.665
axon guidance GO:0007411 141 0.664
cellular response to acid chemical GO:0071229 68 0.663
mitral valve morphogenesis GO:0003183 4 0.662
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.659
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.657
forebrain generation of neurons GO:0021872 63 0.656
forebrain neuron differentiation GO:0021879 52 0.655
negative regulation of immature t cell proliferation GO:0033087 3 0.653
oligodendrocyte differentiation GO:0048709 53 0.652
negative regulation of protein metabolic process GO:0051248 282 0.651
regulation of secretion by cell GO:1903530 249 0.650
nucleoside triphosphate metabolic process GO:0009141 230 0.649
stem cell proliferation GO:0072089 117 0.647
regulation of gtp catabolic process GO:0033124 113 0.647
somatic stem cell maintenance GO:0035019 47 0.644
nucleoside triphosphate catabolic process GO:0009143 205 0.644
gastrulation GO:0007369 116 0.643
positive regulation of hydrolase activity GO:0051345 148 0.643
negative regulation of mesodermal cell fate specification GO:0042662 3 0.643
regulation of epithelial cell proliferation GO:0050678 141 0.642
blastoderm segmentation GO:0007350 13 0.641
cellular senescence GO:0090398 11 0.638
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.637
positive regulation of hormone secretion GO:0046887 38 0.637
protein kinase b signaling GO:0043491 74 0.634
regulation of neuron projection development GO:0010975 169 0.634
pallium development GO:0021543 120 0.633
camera type eye development GO:0043010 266 0.630
pole plasm assembly GO:0007315 2 0.629
apoptotic signaling pathway GO:0097190 306 0.627
posttranscriptional regulation of gene expression GO:0010608 155 0.626
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.626
regulation of mapk cascade GO:0043408 248 0.626
digestive system development GO:0055123 200 0.625
regulation of mitotic cell cycle phase transition GO:1901990 73 0.624
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.623
negative regulation of cellular protein metabolic process GO:0032269 247 0.620
liver development GO:0001889 66 0.618
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.617
pigment metabolic process GO:0042440 32 0.613
glycosyl compound catabolic process GO:1901658 206 0.613
cartilage condensation GO:0001502 18 0.613
regulation of cellular amine metabolic process GO:0033238 20 0.611
embryonic epithelial tube formation GO:0001838 130 0.608
alpha beta t cell differentiation GO:0046632 69 0.606
gtp metabolic process GO:0046039 144 0.606
regulation of protein localization to nucleus GO:1900180 60 0.606
oogenesis GO:0048477 56 0.606
purine ribonucleotide catabolic process GO:0009154 208 0.604
homeostasis of number of cells GO:0048872 210 0.602
aromatic compound catabolic process GO:0019439 286 0.601
regulation of hydrolase activity GO:0051336 246 0.600
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.600
regulation of neuron apoptotic process GO:0043523 122 0.598
cell division GO:0051301 120 0.598
macromolecule catabolic process GO:0009057 281 0.598
glial cell differentiation GO:0010001 131 0.596
membrane organization GO:0061024 245 0.595
t cell differentiation GO:0030217 174 0.595
respiratory tube development GO:0030323 167 0.595
astrocyte activation GO:0048143 2 0.592
axonogenesis GO:0007409 274 0.590
nephron morphogenesis GO:0072028 69 0.588
cellular homeostasis GO:0019725 240 0.586
positive regulation of cellular catabolic process GO:0031331 148 0.586
regulation of cellular response to growth factor stimulus GO:0090287 82 0.585
positive regulation of wound healing GO:0090303 17 0.582
negative regulation of cell cycle GO:0045786 123 0.582
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.581
erbb signaling pathway GO:0038127 32 0.579
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.577
mesonephric tubule development GO:0072164 94 0.574
epithelial tube formation GO:0072175 130 0.574
bone mineralization GO:0030282 54 0.570
positive regulation of secretion by cell GO:1903532 114 0.569
oocyte development GO:0048599 33 0.565
lymphocyte proliferation GO:0046651 164 0.565
peptide hormone secretion GO:0030072 109 0.564
apoptotic process involved in mammary gland involution GO:0060057 4 0.564
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.563
respiratory system development GO:0060541 190 0.561
circulatory system process GO:0003013 197 0.561
endocardium formation GO:0060214 4 0.559
purine nucleoside triphosphate metabolic process GO:0009144 226 0.555
positive regulation of cellular amine metabolic process GO:0033240 5 0.554
regulation of skeletal muscle fiber development GO:0048742 36 0.553
positive regulation of cell development GO:0010720 237 0.553
negative regulation of organ growth GO:0046621 17 0.550
negative regulation of nervous system development GO:0051961 156 0.547
cardiac muscle tissue development GO:0048738 130 0.547
embryonic placenta development GO:0001892 98 0.546
cellular response to hormone stimulus GO:0032870 150 0.544
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.542
neural tube development GO:0021915 160 0.541
negative regulation of ras protein signal transduction GO:0046580 18 0.539
regulation of purine nucleotide metabolic process GO:1900542 169 0.539
cell fate specification GO:0001708 72 0.537
blastocyst development GO:0001824 80 0.535
cognition GO:0050890 149 0.534
myelination GO:0042552 74 0.534
biomineral tissue development GO:0031214 64 0.532
positive regulation of transferase activity GO:0051347 167 0.532
trachea development GO:0060438 18 0.530
inner cell mass cellular morphogenesis GO:0001828 1 0.530
mitotic cell cycle GO:0000278 195 0.526
negative regulation of lymphocyte differentiation GO:0045620 32 0.525
nucleotide catabolic process GO:0009166 217 0.525
kidney development GO:0001822 213 0.524
negative regulation of cell activation GO:0050866 111 0.524
nucleoside metabolic process GO:0009116 246 0.522
photoreceptor cell differentiation GO:0046530 52 0.521
neural tube formation GO:0001841 108 0.521
response to oxidative stress GO:0006979 123 0.519
Fly
response to monosaccharide GO:0034284 67 0.519
female gamete generation GO:0007292 74 0.517
regulation of lipid metabolic process GO:0019216 118 0.517
septum primum development GO:0003284 4 0.515
regulation of myoblast differentiation GO:0045661 29 0.512
spinal cord development GO:0021510 81 0.511
regulation of membrane potential GO:0042391 192 0.511
leukocyte migration GO:0050900 124 0.510
regulation of cardiac cell fate specification GO:2000043 1 0.509
kidney epithelium development GO:0072073 121 0.509
positive regulation of lipid metabolic process GO:0045834 40 0.508
pigmentation GO:0043473 71 0.508
regulation of lymphocyte differentiation GO:0045619 107 0.501
positive regulation of kinase activity GO:0033674 155 0.501
negative regulation of neuron apoptotic process GO:0043524 92 0.499
fibroblast migration GO:0010761 21 0.497
spermatogenesis GO:0007283 284 0.496
schwann cell proliferation GO:0014010 2 0.493
regulation of cell motility GO:2000145 236 0.492
positive regulation of neuron projection development GO:0010976 79 0.492
response to nutrient levels GO:0031667 109 0.491
lung development GO:0030324 164 0.490
ephrin receptor signaling pathway GO:0048013 20 0.490
purine nucleotide metabolic process GO:0006163 302 0.490
protein localization to organelle GO:0033365 185 0.489
endocardium development GO:0003157 10 0.488
regulation of t cell proliferation GO:0042129 92 0.487
immune effector process GO:0002252 321 0.487
purine containing compound catabolic process GO:0072523 213 0.486
response to radiation GO:0009314 165 0.481
positive regulation of hippo signaling GO:0035332 1 0.479
mammary gland epithelium development GO:0061180 65 0.478
somite development GO:0061053 81 0.475
myotube cell development GO:0014904 60 0.474
erythrocyte differentiation GO:0030218 88 0.474
skin development GO:0043588 220 0.473
sequestering of calcium ion GO:0051208 18 0.469
actomyosin structure organization GO:0031032 56 0.468
positive regulation of osteoblast proliferation GO:0033690 9 0.465
regulation of protein targeting GO:1903533 61 0.464
regulation of stress activated mapk cascade GO:0032872 69 0.464
pigment cell differentiation GO:0050931 27 0.464
autophagy GO:0006914 45 0.462
hemostasis GO:0007599 78 0.461
negative regulation of ossification GO:0030279 49 0.461
positive regulation of cell cycle GO:0045787 92 0.460
positive regulation of ras protein signal transduction GO:0046579 13 0.458
regulation of cell cycle phase transition GO:1901987 77 0.458
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.457
positive regulation of rac gtpase activity GO:0032855 14 0.457
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.456
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.456
nephron tubule development GO:0072080 84 0.455
regulation of osteoblast proliferation GO:0033688 15 0.455
positive regulation of nucleotide metabolic process GO:0045981 114 0.454
positive regulation of cell adhesion GO:0045785 80 0.451
branching involved in ureteric bud morphogenesis GO:0001658 56 0.446
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.446
positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718 2 0.446
regulation of lymphocyte activation GO:0051249 240 0.443
sensory perception GO:0007600 245 0.442
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.442
nephron development GO:0072006 109 0.442
positive regulation of peptide secretion GO:0002793 33 0.437
mesonephric tubule morphogenesis GO:0072171 63 0.436
cell cycle g1 s phase transition GO:0044843 57 0.433
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.433
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 1 0.432
central nervous system neuron differentiation GO:0021953 162 0.432
regulation of mitotic cell cycle GO:0007346 126 0.431
medulla oblongata development GO:0021550 3 0.429
regulation of erk1 and erk2 cascade GO:0070372 71 0.427
Zebrafish
positive regulation of leukocyte differentiation GO:1902107 86 0.427
response to peptide GO:1901652 136 0.426
carbon catabolite activation of transcription GO:0045991 4 0.424
regulation of jak stat cascade GO:0046425 34 0.423
regulation of photoreceptor cell differentiation GO:0046532 4 0.422
digestive tract development GO:0048565 190 0.418
response to epidermal growth factor GO:0070849 4 0.418
purine nucleoside triphosphate catabolic process GO:0009146 203 0.414
neurotransmitter transport GO:0006836 76 0.413
regulation of response to wounding GO:1903034 189 0.412
muscle tissue development GO:0060537 308 0.411
regulation of organ growth GO:0046620 61 0.410
calcium ion transport GO:0006816 159 0.408
soft palate development GO:0060023 2 0.408
positive regulation of programmed cell death GO:0043068 218 0.407
segmentation GO:0035282 93 0.407
ribonucleoside triphosphate metabolic process GO:0009199 220 0.405
jak stat cascade GO:0007259 42 0.405
stem cell fate specification GO:0048866 3 0.403
mesenchymal cell differentiation GO:0048762 107 0.402
regulation of cell cycle process GO:0010564 160 0.399
response to transforming growth factor beta GO:0071559 88 0.398
regulation of leukocyte proliferation GO:0070663 121 0.398
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.397
regulation of glial cell proliferation GO:0060251 8 0.395
Zebrafish
regulation of apoptotic signaling pathway GO:2001233 197 0.394
cellular amine metabolic process GO:0044106 44 0.393
inositol lipid mediated signaling GO:0048017 41 0.393
regulation of cell fate specification GO:0042659 10 0.393
establishment of vesicle localization GO:0051650 81 0.392
response to heparin GO:0071503 1 0.391
embryonic skeletal system development GO:0048706 120 0.391
metanephric nephron tubule formation GO:0072289 4 0.389
lens development in camera type eye GO:0002088 62 0.389
positive regulation of map kinase activity GO:0043406 84 0.389
lens epithelial cell proliferation GO:0097166 1 0.388
negative regulation of cell fate specification GO:0009996 4 0.388
adipose tissue development GO:0060612 25 0.387
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.386
anatomical structure homeostasis GO:0060249 145 0.385
neural tube closure GO:0001843 90 0.385
germ line stem cell division GO:0042078 2 0.385
tor signaling GO:0031929 21 0.384
protein import into nucleus GO:0006606 95 0.384
cellular response to monosaccharide stimulus GO:0071326 47 0.383
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.383
regulation of embryonic development GO:0045995 71 0.380
skeletal muscle fiber development GO:0048741 58 0.380
g protein coupled receptor signaling pathway GO:0007186 243 0.377
positive regulation of bmp signaling pathway GO:0030513 23 0.376
gonad development GO:0008406 141 0.376
mammary gland morphogenesis GO:0060443 54 0.375
olfactory learning GO:0008355 2 0.372
Fly
protein autophosphorylation GO:0046777 61 0.371
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.370
organophosphate catabolic process GO:0046434 232 0.368
transmission of nerve impulse GO:0019226 76 0.366
sensory perception of sound GO:0007605 97 0.363
angiogenesis GO:0001525 201 0.362
closure of optic fissure GO:0061386 2 0.360
cellular response to peptide hormone stimulus GO:0071375 92 0.357
ensheathment of neurons GO:0007272 76 0.356
peptidyl tyrosine phosphorylation GO:0018108 143 0.356
chemotaxis GO:0006935 247 0.354
development of primary male sexual characteristics GO:0046546 88 0.354
developmental pigmentation GO:0048066 40 0.354
learning or memory GO:0007611 148 0.352
cellular response to drug GO:0035690 15 0.352
muscle cell development GO:0055001 133 0.352
peripheral nervous system development GO:0007422 53 0.351
formation of primary germ layer GO:0001704 77 0.348
dendrite development GO:0016358 115 0.347
cell chemotaxis GO:0060326 81 0.347
mitotic cell cycle process GO:1903047 159 0.347
g0 to g1 transition GO:0045023 3 0.345
cellular response to insulin stimulus GO:0032869 78 0.345
negative regulation of protein depolymerization GO:1901880 21 0.344
regulation of ras gtpase activity GO:0032318 88 0.343
regulation of map kinase activity GO:0043405 120 0.342
gall bladder development GO:0061010 2 0.342
hepaticobiliary system development GO:0061008 67 0.341
vesicle organization GO:0016050 60 0.341
retinal rod cell differentiation GO:0060221 2 0.341
regulation of actin cytoskeleton organization GO:0032956 84 0.341
endocytosis GO:0006897 168 0.340
cation transport GO:0006812 399 0.340
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.340
positive regulation of lipid kinase activity GO:0090218 11 0.340
cellular macromolecule catabolic process GO:0044265 206 0.339
regulation of stem cell differentiation GO:2000736 50 0.338
pro b cell differentiation GO:0002328 10 0.336
vesicle localization GO:0051648 86 0.333
dna metabolic process GO:0006259 303 0.333
tissue homeostasis GO:0001894 115 0.332
regulation of protein catabolic process GO:0042176 108 0.331
ascending aorta morphogenesis GO:0035910 3 0.331

Nf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.940
Human
cancer DOID:162 0 0.697
Human
organ system cancer DOID:0050686 0 0.697
Human