|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
4 |
0.994
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.991
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.991
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.990
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
1 |
0.989
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.988
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.987
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.984
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.983
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.981
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.974
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.974
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.972
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.971
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.971
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.969
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.968
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.968
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.966
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.966
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.965
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.963
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.955
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.954
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.953
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.953
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.949
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.945
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.941
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.937
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.937
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.935
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.934
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.927
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.927
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.926
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.924
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.921
|
|
|
|
negative regulation of synaptic vesicle exocytosis
|
GO:2000301 |
3 |
0.919
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.919
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.918
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
4 |
0.918
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.917
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.916
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.915
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.912
|
|
|
|
negative regulation of fibroblast migration
|
GO:0010764 |
2 |
0.909
|
|
|
|
atrial septum primum morphogenesis
|
GO:0003289 |
3 |
0.907
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.906
|
Zebrafish |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.905
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.904
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.904
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.901
|
|
|
|
negative regulation of photoreceptor cell differentiation
|
GO:0046533 |
4 |
0.901
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.900
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.899
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.898
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.894
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.893
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.892
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.890
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.889
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.887
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.886
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.885
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.884
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.883
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.883
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.882
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.880
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.874
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.873
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.873
|
|
|
|
negative regulation of synaptic vesicle transport
|
GO:1902804 |
3 |
0.871
|
|
|
|
positive regulation of skeletal muscle tissue regeneration
|
GO:0043415 |
4 |
0.870
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.868
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.868
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.867
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.865
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.864
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.863
|
|
|
|
endodermal cell fate determination
|
GO:0007493 |
2 |
0.862
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.860
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.856
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.855
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.855
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.855
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.855
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.853
|
|
|
|
learning
|
GO:0007612 |
98 |
0.852
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.850
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.847
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
23 |
0.845
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.845
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.844
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.843
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.839
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.838
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.835
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.834
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
8 |
0.831
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.828
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.825
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.824
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.821
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.817
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.816
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.813
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.812
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.811
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.810
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.809
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.808
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.803
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.802
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.800
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.795
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.795
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.794
|
Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.793
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.792
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.791
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.790
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.783
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.783
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.783
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.779
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.778
|
|
|
|
sertoli cell differentiation
|
GO:0060008 |
18 |
0.777
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.774
|
Fly |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.773
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.770
|
|
|
|
zygotic determination of anterior posterior axis embryo
|
GO:0007354 |
3 |
0.770
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.770
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.764
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.761
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.761
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.760
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.757
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.755
|
|
|
|
chondrocyte hypertrophy
|
GO:0003415 |
4 |
0.754
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.750
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.750
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.749
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.748
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.747
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.747
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.746
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.744
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.743
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
12 |
0.742
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.740
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.737
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.735
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.734
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.734
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.734
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.731
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.730
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.728
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.728
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.726
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.726
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.725
|
|
|
|
regulation of lens epithelial cell proliferation
|
GO:2001109 |
1 |
0.718
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.715
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.714
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.714
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.714
|
|
|
|
glial cell proliferation
|
GO:0014009 |
10 |
0.712
|
Zebrafish |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.711
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.711
|
|
|
|
neural crest cell migration
|
GO:0001755 |
32 |
0.708
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.706
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.703
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.702
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.701
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.701
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
4 |
0.700
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.700
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.700
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.700
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.696
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.696
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.695
|
|
|
|
ureter morphogenesis
|
GO:0072197 |
4 |
0.695
|
|
|
|
neural crest cell development
|
GO:0014032 |
48 |
0.693
|
|
|
|
primary prostatic bud elongation
|
GO:0060516 |
2 |
0.691
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.690
|
|
|
|
positive regulation of lens epithelial cell proliferation
|
GO:2001111 |
1 |
0.690
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.690
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.689
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.686
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.682
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.680
|
|
|
|
smooth muscle tissue development
|
GO:0048745 |
22 |
0.679
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.679
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.678
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.677
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
31 |
0.677
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.675
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.674
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.674
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.671
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.671
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.668
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
26 |
0.667
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.667
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.667
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.667
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.665
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.664
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.663
|
|
|
|
mitral valve morphogenesis
|
GO:0003183 |
4 |
0.662
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.659
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.657
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.656
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.655
|
|
|
|
negative regulation of immature t cell proliferation
|
GO:0033087 |
3 |
0.653
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.652
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.651
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.650
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.649
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.647
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.647
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.644
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.644
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.643
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.643
|
|
|
|
negative regulation of mesodermal cell fate specification
|
GO:0042662 |
3 |
0.643
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.642
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
13 |
0.641
|
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.638
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.637
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.637
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.634
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.634
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.633
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.630
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.629
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.627
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.626
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.626
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.626
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.625
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.624
|
|
|
|
regulation of transcription involved in primary germ layer cell fate commitment
|
GO:0060796 |
2 |
0.623
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.620
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.618
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.617
|
|
|
|
pigment metabolic process
|
GO:0042440 |
32 |
0.613
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.613
|
|
|
|
cartilage condensation
|
GO:0001502 |
18 |
0.613
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.611
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.608
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.606
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.606
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.606
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.606
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.604
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.602
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.601
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.600
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.600
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.598
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.598
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.598
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.596
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.595
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.595
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.595
|
|
|
|
astrocyte activation
|
GO:0048143 |
2 |
0.592
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.590
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.588
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.586
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.586
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.585
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
17 |
0.582
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.582
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.581
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.579
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.577
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.574
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.574
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.570
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.569
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.565
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.565
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.564
|
|
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.564
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.563
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.561
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.561
|
|
|
|
endocardium formation
|
GO:0060214 |
4 |
0.559
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.555
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.554
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.553
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.553
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.550
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.547
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.547
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.546
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.544
|
|
|
|
detection of mechanical stimulus involved in equilibrioception
|
GO:0050973 |
2 |
0.542
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.541
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.539
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.539
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.537
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.535
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.534
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.534
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.532
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.532
|
|
|
|
trachea development
|
GO:0060438 |
18 |
0.530
|
|
|
|
inner cell mass cellular morphogenesis
|
GO:0001828 |
1 |
0.530
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.526
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.525
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.525
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.524
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.524
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.522
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.521
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.521
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.519
|
Fly |
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.519
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.517
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.517
|
|
|
|
septum primum development
|
GO:0003284 |
4 |
0.515
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.512
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.511
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.511
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.510
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.509
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.509
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.508
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.508
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.501
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.501
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.499
|
|
|
|
fibroblast migration
|
GO:0010761 |
21 |
0.497
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.496
|
|
|
|
schwann cell proliferation
|
GO:0014010 |
2 |
0.493
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.492
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.492
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.491
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.490
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
20 |
0.490
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.490
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.489
|
|
|
|
endocardium development
|
GO:0003157 |
10 |
0.488
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.487
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.487
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.486
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.481
|
|
|
|
positive regulation of hippo signaling
|
GO:0035332 |
1 |
0.479
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.478
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.475
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.474
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.474
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.473
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.469
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.468
|
|
|
|
positive regulation of osteoblast proliferation
|
GO:0033690 |
9 |
0.465
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.464
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.464
|
|
|
|
pigment cell differentiation
|
GO:0050931 |
27 |
0.464
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.462
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.461
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.461
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.460
|
|
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
13 |
0.458
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.458
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.457
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.457
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.456
|
Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.456
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.455
|
|
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
15 |
0.455
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.454
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.451
|
|
|
|
branching involved in ureteric bud morphogenesis
|
GO:0001658 |
56 |
0.446
|
|
|
|
negative regulation of wnt signaling pathway involved in heart development
|
GO:0003308 |
4 |
0.446
|
|
|
|
positive regulation of satellite cell activation involved in skeletal muscle regeneration
|
GO:0014718 |
2 |
0.446
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.443
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.442
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.442
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.442
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.437
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.436
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.433
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.433
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
1 |
0.432
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.432
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.431
|
|
|
|
medulla oblongata development
|
GO:0021550 |
3 |
0.429
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.427
|
Zebrafish |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.427
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.426
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.424
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.423
|
|
|
|
regulation of photoreceptor cell differentiation
|
GO:0046532 |
4 |
0.422
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.418
|
|
|
|
response to epidermal growth factor
|
GO:0070849 |
4 |
0.418
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.414
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.413
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.412
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.411
|
|
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.410
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.408
|
|
|
|
soft palate development
|
GO:0060023 |
2 |
0.408
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.407
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.407
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.405
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.405
|
|
|
|
stem cell fate specification
|
GO:0048866 |
3 |
0.403
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.402
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.399
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.398
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.398
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.397
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
8 |
0.395
|
Zebrafish |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.394
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.393
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.393
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
10 |
0.393
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.392
|
|
|
|
response to heparin
|
GO:0071503 |
1 |
0.391
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.391
|
|
|
|
metanephric nephron tubule formation
|
GO:0072289 |
4 |
0.389
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.389
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.389
|
|
|
|
lens epithelial cell proliferation
|
GO:0097166 |
1 |
0.388
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
4 |
0.388
|
|
|
|
adipose tissue development
|
GO:0060612 |
25 |
0.387
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.386
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.385
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.385
|
|
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.385
|
|
|
|
tor signaling
|
GO:0031929 |
21 |
0.384
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.384
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.383
|
|
|
|
epithelial cell proliferation involved in prostatic bud elongation
|
GO:0060517 |
1 |
0.383
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.380
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.380
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.377
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
23 |
0.376
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.376
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.375
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.372
|
Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.371
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.370
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.368
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.366
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.363
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.362
|
|
|
|
closure of optic fissure
|
GO:0061386 |
2 |
0.360
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.357
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.356
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.356
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.354
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.354
|
|
|
|
developmental pigmentation
|
GO:0048066 |
40 |
0.354
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.352
|
|
|
|
cellular response to drug
|
GO:0035690 |
15 |
0.352
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.352
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.351
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.348
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.347
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.347
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.347
|
|
|
|
g0 to g1 transition
|
GO:0045023 |
3 |
0.345
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.345
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
21 |
0.344
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.343
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.342
|
|
|
|
gall bladder development
|
GO:0061010 |
2 |
0.342
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.341
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.341
|
|
|
|
retinal rod cell differentiation
|
GO:0060221 |
2 |
0.341
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.341
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.340
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.340
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.340
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.340
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.339
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.338
|
|
|
|
pro b cell differentiation
|
GO:0002328 |
10 |
0.336
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.333
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.333
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.332
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.331
|
|
|
|
ascending aorta morphogenesis
|
GO:0035910 |
3 |
0.331
|
|
