Mus musculus

144 known processes

Nfe2l2

nuclear factor, erythroid derived 2, like 2

(Aliases: AI194320,Nrf2)

Nfe2l2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular response to stress GO:0080135 159 0.888
positive regulation of apoptotic process GO:0043065 217 0.867
lymphocyte homeostasis GO:0002260 64 0.819
response to chromate GO:0046687 1 0.813
cellular ion homeostasis GO:0006873 165 0.789
regulation of cellular amine metabolic process GO:0033238 20 0.781
positive regulation of cell death GO:0010942 224 0.737
metal ion homeostasis GO:0055065 189 0.719
cellular response to inorganic substance GO:0071241 37 0.710
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.709
Human
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.706
myeloid cell homeostasis GO:0002262 114 0.694
Mouse
leukocyte homeostasis GO:0001776 79 0.690
intrinsic apoptotic signaling pathway GO:0097193 132 0.669
Human
cation homeostasis GO:0055080 212 0.662
response to extracellular stimulus GO:0009991 127 0.658
lipid biosynthetic process GO:0008610 179 0.621
nucleocytoplasmic transport GO:0006913 139 0.602
cell type specific apoptotic process GO:0097285 268 0.601
Human
blood coagulation GO:0007596 76 0.600
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.591
cytokine production GO:0001816 319 0.571
regulation of body fluid levels GO:0050878 162 0.550
epidermis development GO:0008544 187 0.543
response to nutrient levels GO:0031667 109 0.537
regulation of response to wounding GO:1903034 189 0.532
regulation of membrane potential GO:0042391 192 0.531
zinc ion homeostasis GO:0055069 10 0.522
leukocyte apoptotic process GO:0071887 71 0.522
positive regulation of apoptotic signaling pathway GO:2001235 95 0.519
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.518
homeostasis of number of cells GO:0048872 210 0.517
Mouse
glycerolipid biosynthetic process GO:0045017 50 0.504
amine metabolic process GO:0009308 45 0.501
negative regulation of neuron death GO:1901215 98 0.497
cellular lipid metabolic process GO:0044255 323 0.482
peptidyl amino acid modification GO:0018193 336 0.478
Mouse
hemostasis GO:0007599 78 0.474
regulation of cytokine production GO:0001817 266 0.454
cellular response to dna damage stimulus GO:0006974 207 0.448
lymphocyte mediated immunity GO:0002449 139 0.446
cellular response to external stimulus GO:0071496 88 0.416
regulation of leukocyte apoptotic process GO:2000106 56 0.415
regulation of ion transport GO:0043269 215 0.414
sphingolipid metabolic process GO:0006665 45 0.414
neuron apoptotic process GO:0051402 142 0.407
t cell apoptotic process GO:0070231 39 0.406
response to inorganic substance GO:0010035 96 0.404
regulation of reactive oxygen species metabolic process GO:2000377 40 0.397
positive regulation of protein kinase activity GO:0045860 144 0.385
regulation of neuron apoptotic process GO:0043523 122 0.381
apoptotic signaling pathway GO:0097190 306 0.373
Human
myeloid leukocyte activation GO:0002274 83 0.366
positive regulation of cytokine production GO:0001819 174 0.365
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.362
Human
positive regulation of protein phosphorylation GO:0001934 242 0.361
cellular zinc ion homeostasis GO:0006882 9 0.359
neuron death GO:0070997 154 0.353
regulation of kinase activity GO:0043549 249 0.351
t cell differentiation in thymus GO:0033077 77 0.351
ear development GO:0043583 200 0.349
positive regulation of programmed cell death GO:0043068 218 0.346
cellular response to antibiotic GO:0071236 4 0.345
cellular protein catabolic process GO:0044257 155 0.335
Human
single organism nuclear import GO:1902593 95 0.334
regulation of apoptotic signaling pathway GO:2001233 197 0.332
Human
stress response to metal ion GO:0097501 3 0.331
negative regulation of apoptotic signaling pathway GO:2001234 104 0.318
Human
organophosphate biosynthetic process GO:0090407 122 0.317
organonitrogen compound biosynthetic process GO:1901566 192 0.316
cellular response to extracellular stimulus GO:0031668 81 0.314
cellular response to radiation GO:0071478 28 0.312
glial cell differentiation GO:0010001 131 0.311
negative regulation of neuron apoptotic process GO:0043524 92 0.307
regulation of protein kinase activity GO:0045859 232 0.306
cellular amine metabolic process GO:0044106 44 0.300
cellular response to cytokine stimulus GO:0071345 189 0.299
Human
cellular divalent inorganic cation homeostasis GO:0072503 127 0.298
positive regulation of defense response GO:0031349 124 0.295
digestive system development GO:0055123 200 0.295
Fly
fibroblast proliferation GO:0048144 35 0.291
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.289
maintenance of location GO:0051235 89 0.288
Fly
response to organic cyclic compound GO:0014070 198 0.287
coagulation GO:0050817 78 0.282
response to reactive oxygen species GO:0000302 56 0.281
response to drug GO:0042493 75 0.270
cellular response to metal ion GO:0071248 31 0.267
ion transmembrane transport GO:0034220 361 0.267
inflammatory response to wounding GO:0090594 4 0.261
mitochondrion organization GO:0007005 134 0.255
negative regulation of growth GO:0045926 99 0.254
lipid homeostasis GO:0055088 63 0.253
positive regulation of glial cell proliferation GO:0060252 4 0.246
developmental maturation GO:0021700 193 0.245
Fly
defense response to other organism GO:0098542 197 0.244
response to radiation GO:0009314 165 0.243
membrane organization GO:0061024 245 0.243
regulation of protein localization GO:0032880 231 0.242
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 3 0.241
negative regulation of cytokine production GO:0001818 84 0.239
divalent inorganic cation homeostasis GO:0072507 138 0.239
defense response to bacterium GO:0042742 119 0.237
apoptotic process involved in mammary gland involution GO:0060057 4 0.234
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.229
Human
positive regulation of neuron apoptotic process GO:0043525 25 0.228
nitric oxide mediated signal transduction GO:0007263 4 0.226
protein lipid complex subunit organization GO:0071825 12 0.223
keratinocyte migration GO:0051546 3 0.221
phosphatidic acid metabolic process GO:0046473 2 0.221
skin development GO:0043588 220 0.220
regulation of ossification GO:0030278 112 0.217
Mouse
positive regulation of mapk cascade GO:0043410 170 0.216
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.215
organic anion transport GO:0015711 137 0.215
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.214
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.212
protein catabolic process GO:0030163 221 0.212
Human
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.208
phosphatidic acid biosynthetic process GO:0006654 2 0.204
positive regulation of homeostatic process GO:0032846 64 0.204
response to light stimulus GO:0009416 135 0.202
granulocyte migration GO:0097530 43 0.201
peptidyl serine modification GO:0018209 83 0.200
epithelial cell proliferation GO:0050673 174 0.196
intracellular receptor signaling pathway GO:0030522 74 0.196
activation of cysteine type endopeptidase activity GO:0097202 27 0.193
transmission of nerve impulse GO:0019226 76 0.191
regulation of cellular response to oxidative stress GO:1900407 19 0.191
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.190
cellular response to zinc ion GO:0071294 3 0.189
glycerophospholipid biosynthetic process GO:0046474 32 0.187
cellular chemical homeostasis GO:0055082 215 0.187
mammary gland epithelium development GO:0061180 65 0.184
myeloid cell differentiation GO:0030099 233 0.183
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.182
Fly
regulation of peptidase activity GO:0052547 96 0.181
b cell proliferation GO:0042100 53 0.180
protein localization to nucleus GO:0034504 121 0.180
anatomical structure homeostasis GO:0060249 145 0.179
chemotaxis GO:0006935 247 0.178
cytoplasmic transport GO:0016482 234 0.177
cellular transition metal ion homeostasis GO:0046916 32 0.176
positive regulation of organelle organization GO:0010638 128 0.173
ubiquitin dependent protein catabolic process GO:0006511 129 0.170
Human
urogenital system development GO:0001655 261 0.168
cell maturation GO:0048469 127 0.167
Fly
cellular amide metabolic process GO:0043603 58 0.167
transition metal ion homeostasis GO:0055076 54 0.167
regulation of cellular ketone metabolic process GO:0010565 66 0.165
cellular response to abiotic stimulus GO:0071214 56 0.163
regulation of lipid storage GO:0010883 20 0.162
negative regulation of phosphorylation GO:0042326 166 0.158
myeloid cell apoptotic process GO:0033028 22 0.156
cellular homeostasis GO:0019725 240 0.155
b cell activation GO:0042113 161 0.155
response to peptide hormone GO:0043434 127 0.154
response to endoplasmic reticulum stress GO:0034976 53 0.154
protein localization to organelle GO:0033365 185 0.153
regulation of peptidyl serine phosphorylation GO:0033135 39 0.152
skeletal system development GO:0001501 356 0.152
ribonucleotide metabolic process GO:0009259 291 0.152
development of primary sexual characteristics GO:0045137 143 0.151
response to oxidative stress GO:0006979 123 0.150
positive regulation of kinase activity GO:0033674 155 0.149
positive regulation of secretion by cell GO:1903532 114 0.148
modification dependent macromolecule catabolic process GO:0043632 133 0.148
Human
female sex differentiation GO:0046660 84 0.146
regulation of transforming growth factor beta2 production GO:0032909 2 0.145
dendrite development GO:0016358 115 0.145
Fly
positive regulation of proteolysis GO:0045862 85 0.144
regulation of establishment of protein localization GO:0070201 181 0.144
g1 s transition of mitotic cell cycle GO:0000082 57 0.143
cellular response to oxidative stress GO:0034599 76 0.143
multicellular organismal aging GO:0010259 24 0.143
Fly
regulation of transferase activity GO:0051338 263 0.142
positive regulation of protein modification process GO:0031401 299 0.142
Mouse
positive regulation of phagocytosis GO:0050766 26 0.142
neuronal action potential GO:0019228 54 0.141
development of primary female sexual characteristics GO:0046545 73 0.140
response to steroid hormone GO:0048545 56 0.139
modification by symbiont of host morphology or physiology GO:0044003 4 0.139
triglyceride metabolic process GO:0006641 51 0.135
lipid localization GO:0010876 126 0.135
fertilization GO:0009566 127 0.135
gonad development GO:0008406 141 0.134
inflammatory response GO:0006954 244 0.134
negative regulation of cell cycle GO:0045786 123 0.133
regulation of lymphocyte apoptotic process GO:0070228 41 0.132
regulation of hemostasis GO:1900046 28 0.131
hypoxia inducible factor 1alpha signaling pathway GO:0097411 2 0.131
regulation of neuron death GO:1901214 134 0.130
action potential GO:0001508 78 0.130
cellular response to toxic substance GO:0097237 7 0.129
rhythmic process GO:0048511 174 0.128
regulation of mitotic cell cycle phase transition GO:1901990 73 0.128
negative regulation of homeostatic process GO:0032845 71 0.128
glycoprotein metabolic process GO:0009100 116 0.126
negative regulation of protein metabolic process GO:0051248 282 0.126
membrane lipid metabolic process GO:0006643 53 0.125
signal transduction in absence of ligand GO:0038034 55 0.124
gas homeostasis GO:0033483 3 0.124
regulation of b cell activation GO:0050864 81 0.124
regulation of cell cycle GO:0051726 281 0.123
phospholipid biosynthetic process GO:0008654 36 0.123
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.122
tissue homeostasis GO:0001894 115 0.122
response to transition metal nanoparticle GO:1990267 11 0.122
regulation of protein transport GO:0051223 163 0.121
digestive tract morphogenesis GO:0048546 147 0.121
striated muscle tissue development GO:0014706 293 0.120
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.119
apoptotic mitochondrial changes GO:0008637 48 0.118
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.118
negative regulation of interferon gamma mediated signaling pathway GO:0060336 1 0.118
multicellular organismal homeostasis GO:0048871 164 0.117
negative regulation of cellular amine metabolic process GO:0033239 1 0.117
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.117
regulation of proteolysis GO:0030162 164 0.117
regulation of blood coagulation GO:0030193 28 0.116
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.116
transmembrane transport GO:0055085 412 0.115
regulation of lipid metabolic process GO:0019216 118 0.115
regulation of vesicle mediated transport GO:0060627 139 0.114
glycerolipid metabolic process GO:0046486 122 0.114
regulation of cellular catabolic process GO:0031329 242 0.113
fatty acid metabolic process GO:0006631 121 0.112
nuclear import GO:0051170 95 0.112
negative regulation of mapk cascade GO:0043409 65 0.111
regulation of protein targeting GO:1903533 61 0.111
spleen development GO:0048536 39 0.111
regulation of acute inflammatory response GO:0002673 27 0.111
respiratory tube development GO:0030323 167 0.110
erythrocyte differentiation GO:0030218 88 0.108
Mouse
regulation of cellular protein catabolic process GO:1903362 61 0.108
regulation of inflammatory response GO:0050727 147 0.107
muscle tissue development GO:0060537 308 0.106
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.106
carbohydrate derivative biosynthetic process GO:1901137 183 0.106
regulation of innate immune response GO:0045088 91 0.105
regulation of cell activation GO:0050865 289 0.105
gland development GO:0048732 330 0.105
positive regulation of immune effector process GO:0002699 107 0.105
response to low density lipoprotein particle GO:0055098 2 0.104
cellular response to hormone stimulus GO:0032870 150 0.104
Zebrafish
cation transport GO:0006812 399 0.104
carboxylic acid transport GO:0046942 100 0.103
regulation of cell cycle phase transition GO:1901987 77 0.102
establishment of protein localization to organelle GO:0072594 118 0.102
myelination GO:0042552 74 0.102
mesenchyme development GO:0060485 152 0.102
regulation of hydrolase activity GO:0051336 246 0.101
regulation of ion homeostasis GO:2000021 64 0.101
mapk cascade GO:0000165 281 0.100
activation of mapkk activity GO:0000186 15 0.099
protein acylation GO:0043543 64 0.099
Mouse
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.099
stress activated mapk cascade GO:0051403 80 0.098
regulation of cell migration GO:0030334 219 0.098
second messenger mediated signaling GO:0019932 73 0.098
regulation of fibroblast proliferation GO:0048145 34 0.097
extrinsic apoptotic signaling pathway GO:0097191 126 0.097
lymphocyte differentiation GO:0030098 242 0.095
myeloid leukocyte migration GO:0097529 57 0.095
negative regulation of protein phosphorylation GO:0001933 126 0.095
regulation of multi organism process GO:0043900 111 0.095
Fly
branching morphogenesis of an epithelial tube GO:0048754 159 0.095
sensory perception GO:0007600 245 0.093
embryonic appendage morphogenesis GO:0035113 126 0.093
organic acid transport GO:0015849 101 0.093
oxidation reduction process GO:0055114 342 0.092
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.091
negative regulation of immune system process GO:0002683 209 0.091
signal transduction by p53 class mediator GO:0072331 51 0.091
regulation of lymphocyte activation GO:0051249 240 0.091
response to metal ion GO:0010038 47 0.090
positive regulation of map kinase activity GO:0043406 84 0.089
odontogenesis GO:0042476 78 0.089
i kappab kinase nf kappab signaling GO:0007249 85 0.088
positive regulation of lymphocyte activation GO:0051251 140 0.088
digestive tract development GO:0048565 190 0.087
Fly
mitochondrial membrane organization GO:0007006 26 0.087
lipid storage GO:0019915 36 0.087
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.086
cytokine mediated signaling pathway GO:0019221 115 0.086
negative regulation of cell growth GO:0030308 44 0.086
dna metabolic process GO:0006259 303 0.085
response to copper ion GO:0046688 3 0.085
neuron maturation GO:0042551 29 0.085
positive regulation of protein complex assembly GO:0031334 45 0.085
response to lipopolysaccharide GO:0032496 128 0.085
limb development GO:0060173 166 0.085
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.085
cellular amino acid metabolic process GO:0006520 103 0.084
innate immune response GO:0045087 157 0.084
receptor biosynthetic process GO:0032800 3 0.084
skin morphogenesis GO:0043589 38 0.084
positive regulation of nervous system development GO:0051962 221 0.083
regulation of nuclear division GO:0051783 56 0.083
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.083
Human
wound healing GO:0042060 157 0.082
b cell differentiation GO:0030183 78 0.082
organelle fission GO:0048285 170 0.081
b cell homeostasis GO:0001782 34 0.081
regulation of homeostatic process GO:0032844 182 0.081
positive regulation of mitochondrion organization GO:0010822 17 0.081
regulation of mammary gland involution GO:1903519 4 0.081
lipid transport GO:0006869 98 0.080
kidney development GO:0001822 213 0.080
wnt signaling pathway GO:0016055 188 0.079
positive regulation of cellular catabolic process GO:0031331 148 0.079
negative regulation of multi organism process GO:0043901 68 0.079
negative regulation of cell proliferation GO:0008285 296 0.079
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.078
skeletal muscle organ development GO:0060538 163 0.078
embryonic placenta development GO:0001892 98 0.077
Mouse
organelle localization GO:0051640 179 0.077
Fly
cellular response to growth factor stimulus GO:0071363 197 0.077
regulation of leukocyte mediated immunity GO:0002703 104 0.076
stress activated protein kinase signaling cascade GO:0031098 81 0.076
cellular response to ionizing radiation GO:0071479 11 0.076
lactation GO:0007595 25 0.076
response to oxygen radical GO:0000305 16 0.076
regulation of endocytosis GO:0030100 69 0.075
phospholipid metabolic process GO:0006644 87 0.075
regulation of wnt signaling pathway GO:0030111 123 0.075
regulation of mast cell differentiation GO:0060375 3 0.075
protein modification by small protein conjugation GO:0032446 187 0.074
Human
odontogenesis of dentin containing tooth GO:0042475 66 0.074
cellular response to organic cyclic compound GO:0071407 87 0.074
nucleoside phosphate metabolic process GO:0006753 338 0.074
autophagy GO:0006914 45 0.074
nucleoside phosphate biosynthetic process GO:1901293 79 0.074
cellular response to light stimulus GO:0071482 19 0.074
sensory perception of mechanical stimulus GO:0050954 107 0.074
positive regulation of response to wounding GO:1903036 66 0.074
response to ionizing radiation GO:0010212 42 0.074
ensheathment of neurons GO:0007272 76 0.073
multicellular organism growth GO:0035264 161 0.073
rho protein signal transduction GO:0007266 32 0.073
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.073
positive regulation of hydrolase activity GO:0051345 148 0.073
response to starvation GO:0042594 65 0.073
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.072
negative regulation of protein modification process GO:0031400 163 0.072
microtubule based process GO:0007017 236 0.072
Fly
modulation by virus of host morphology or physiology GO:0019048 3 0.072
regulation of stress activated mapk cascade GO:0032872 69 0.072
blastocyst development GO:0001824 80 0.071
negative regulation of leukocyte proliferation GO:0070664 46 0.071
response to hyperoxia GO:0055093 2 0.071
regulation of defense response GO:0031347 233 0.071
negative regulation of epithelial cell proliferation GO:0050680 64 0.070
regulation of mitotic cell cycle GO:0007346 126 0.070
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.069
Human
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.069
cellular metal ion homeostasis GO:0006875 151 0.069
regulation of protein complex assembly GO:0043254 83 0.069
sensory perception of sound GO:0007605 97 0.069
cellular response to nutrient levels GO:0031669 64 0.069
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.069
positive regulation of neuron death GO:1901216 28 0.069
positive regulation of interferon alpha production GO:0032727 4 0.068
interspecies interaction between organisms GO:0044419 83 0.068
leukocyte differentiation GO:0002521 342 0.068
cellular response to starvation GO:0009267 57 0.068
regulation of neuron differentiation GO:0045664 281 0.068
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.067
positive regulation of cell cycle GO:0045787 92 0.067
regulation of organelle organization GO:0033043 289 0.066
negative regulation of cellular protein metabolic process GO:0032269 247 0.066
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 3 0.066
regulation of protein serine threonine kinase activity GO:0071900 157 0.066
cellular response to vitamin GO:0071295 2 0.066
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.066
eye photoreceptor cell differentiation GO:0001754 41 0.065
tissue migration GO:0090130 68 0.065
protein import into nucleus GO:0006606 95 0.065
multicellular organismal signaling GO:0035637 91 0.065
purine nucleotide biosynthetic process GO:0006164 65 0.065
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.065
epithelial tube morphogenesis GO:0060562 303 0.064
actin filament organization GO:0007015 113 0.064
hair follicle development GO:0001942 85 0.064
positive regulation of myeloid cell differentiation GO:0045639 43 0.064
regulation of b cell mediated immunity GO:0002712 37 0.064
platelet activation GO:0030168 40 0.063
negative regulation of nervous system development GO:0051961 156 0.063
regulation of intracellular transport GO:0032386 159 0.063
t cell activation GO:0042110 289 0.063
regulation of cytoskeleton organization GO:0051493 122 0.063
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.063
lymphocyte proliferation GO:0046651 164 0.063
peptide metabolic process GO:0006518 46 0.062
stem cell maintenance GO:0019827 130 0.062
macrophage fusion GO:0034238 3 0.062
negative regulation of inflammatory response GO:0050728 61 0.062
glutamate metabolic process GO:0006536 9 0.062
regulation of epithelial cell proliferation GO:0050678 141 0.061
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.061
response to acid chemical GO:0001101 111 0.061
Zebrafish
oxygen homeostasis GO:0032364 2 0.061
reactive nitrogen species metabolic process GO:2001057 0 0.060
regulation of cellular response to hypoxia GO:1900037 2 0.060
intestinal absorption GO:0050892 13 0.060
mammary gland morphogenesis GO:0060443 54 0.060
male sex differentiation GO:0046661 109 0.060
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.059
negative regulation of intracellular signal transduction GO:1902532 167 0.059
Human
protein import GO:0017038 101 0.059
purine ribonucleotide metabolic process GO:0009150 290 0.058
immune response regulating signaling pathway GO:0002764 125 0.058
glycerophospholipid metabolic process GO:0006650 71 0.058
nucleotide biosynthetic process GO:0009165 78 0.057
activation of immune response GO:0002253 138 0.057
nucleoside monophosphate metabolic process GO:0009123 85 0.057
protein oligomerization GO:0051259 67 0.057
positive regulation of osteoclast differentiation GO:0045672 15 0.057
organophosphate ester transport GO:0015748 28 0.056
organic hydroxy compound transport GO:0015850 93 0.056
immune effector process GO:0002252 321 0.056
myeloid leukocyte differentiation GO:0002573 119 0.055
intestinal epithelial structure maintenance GO:0060729 4 0.055
regulation of lymphocyte mediated immunity GO:0002706 84 0.055
release of cytochrome c from mitochondria GO:0001836 23 0.055
acylglycerol metabolic process GO:0006639 55 0.055
positive regulation of cellular component biogenesis GO:0044089 94 0.055
regulation of myeloid cell apoptotic process GO:0033032 19 0.055
acute inflammatory response GO:0002526 41 0.054
positive regulation of secretion GO:0051047 130 0.054
purine containing compound biosynthetic process GO:0072522 70 0.054
positive regulation of innate immune response GO:0045089 80 0.054
regulation of fat cell differentiation GO:0045598 81 0.054
regulation of protein import into nucleus translocation GO:0033158 2 0.053
regulation of fatty acid metabolic process GO:0019217 28 0.053
regulation of calcium ion transport into cytosol GO:0010522 31 0.053
organonitrogen compound catabolic process GO:1901565 264 0.053
t cell homeostasis GO:0043029 35 0.053
calcium ion homeostasis GO:0055074 127 0.053
maternal process involved in female pregnancy GO:0060135 32 0.052
positive regulation of leukocyte apoptotic process GO:2000108 21 0.052
nuclear division GO:0000280 158 0.052
positive regulation of peptidase activity GO:0010952 49 0.052
cholesterol homeostasis GO:0042632 44 0.051
cell adhesion GO:0007155 329 0.051
embryonic limb morphogenesis GO:0030326 126 0.051
negative regulation of endothelial cell migration GO:0010596 4 0.051
anion transport GO:0006820 177 0.051
positive regulation of phagocytosis engulfment GO:0060100 3 0.051
regulation of organ morphogenesis GO:2000027 144 0.051
response to interleukin 15 GO:0070672 3 0.051
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.051
cellular response to lipid GO:0071396 145 0.051
Zebrafish
sensory organ morphogenesis GO:0090596 242 0.051
cellular response to organonitrogen compound GO:0071417 145 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
response to iron ion GO:0010039 4 0.050
regulation of purine nucleotide metabolic process GO:1900542 169 0.049
mast cell apoptotic process GO:0033024 5 0.049
bone development GO:0060348 120 0.049
glial cell apoptotic process GO:0034349 3 0.049
regulation of nucleotide metabolic process GO:0006140 169 0.049
positive regulation of lymphocyte proliferation GO:0050671 70 0.048
macromolecule catabolic process GO:0009057 281 0.048
Human
lung development GO:0030324 164 0.048
positive regulation of gluconeogenesis GO:0045722 11 0.048
regulation of leukocyte differentiation GO:1902105 159 0.048
renal system development GO:0072001 225 0.048
modification dependent protein catabolic process GO:0019941 133 0.048
Human
negative regulation of mitotic cell cycle GO:0045930 58 0.047
cell aging GO:0007569 35 0.047
ras protein signal transduction GO:0007265 77 0.047
cytokine biosynthetic process GO:0042089 68 0.047
hair follicle morphogenesis GO:0031069 29 0.047
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.047
mitochondrial transport GO:0006839 36 0.047
positive regulation of adaptive immune response GO:0002821 61 0.047
regulation of triglyceride biosynthetic process GO:0010866 10 0.047
regulation of transmembrane transport GO:0034762 128 0.047
intracellular protein transport GO:0006886 204 0.047
positive regulation of dendrite development GO:1900006 21 0.047

Nfe2l2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.356
inherited metabolic disorder DOID:655 0 0.356
retinal disease DOID:5679 0 0.268
sensory system disease DOID:0050155 0 0.268
disease of anatomical entity DOID:7 0 0.268
eye and adnexa disease DOID:1492 0 0.268
nervous system disease DOID:863 0 0.268
eye disease DOID:5614 0 0.268
retinal degeneration DOID:8466 0 0.198
immune system disease DOID:2914 0 0.110
disease of cellular proliferation DOID:14566 0 0.095
anemia DOID:2355 0 0.070
hematopoietic system disease DOID:74 0 0.070
integumentary system disease DOID:16 0 0.057