|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
1.000
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
1.000
|
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
1.000
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
1.000
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
1.000
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
1.000
|
Fly |
|
regulation of defense response to fungus
|
GO:1900150 |
1 |
1.000
|
Fly |
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
1.000
|
Fly |
|
nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070427 |
5 |
1.000
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
1.000
|
Fly |
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
1.000
|
Fly |
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
1.000
|
Human Mouse |
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
1.000
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.999
|
Mouse |
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.999
|
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
1 |
0.999
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.999
|
Mouse |
|
response to muramyl dipeptide
|
GO:0032495 |
9 |
0.999
|
Mouse |
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
0.999
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.999
|
Fly |
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.999
|
Human Mouse |
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.999
|
Fly |
|
follicular dendritic cell differentiation
|
GO:0002268 |
2 |
0.998
|
Mouse |
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.998
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.998
|
Fly |
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.998
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.998
|
Mouse |
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.997
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.997
|
Mouse |
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.997
|
Mouse |
|
interleukin 12 biosynthetic process
|
GO:0042090 |
8 |
0.997
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.996
|
Fly |
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.996
|
Fly |
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.996
|
Mouse |
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.994
|
Mouse |
|
activation of immune response
|
GO:0002253 |
138 |
0.993
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.992
|
Fly |
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.991
|
Mouse |
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.991
|
Mouse |
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.989
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.989
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.987
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.987
|
Human Mouse |
|
defense response to fungus
|
GO:0050832 |
12 |
0.986
|
Fly |
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.985
|
Mouse |
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.985
|
Mouse |
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.983
|
|
|
peptide biosynthetic process
|
GO:0043043 |
11 |
0.983
|
Fly |
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.982
|
Mouse |
|
follicular dendritic cell activation
|
GO:0002266 |
2 |
0.981
|
Mouse |
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.979
|
Mouse |
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.979
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.978
|
Fly |
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.977
|
Mouse |
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.977
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.976
|
Mouse |
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.974
|
|
|
regulation of interleukin 10 biosynthetic process
|
GO:0045074 |
1 |
0.973
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.971
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.970
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.968
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.967
|
Mouse |
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.966
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.964
|
Fly |
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.963
|
Mouse |
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
13 |
0.963
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.962
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.961
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.957
|
Human Mouse |
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.957
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.957
|
Mouse |
|
b cell differentiation
|
GO:0030183 |
78 |
0.957
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.954
|
Mouse |
|
t cell activation
|
GO:0042110 |
289 |
0.953
|
Mouse |
|
adaptive immune response
|
GO:0002250 |
155 |
0.951
|
Mouse |
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.950
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.947
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.946
|
Mouse |
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.945
|
Human Mouse |
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.945
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.943
|
Fly |
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.943
|
Fly |
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.942
|
Mouse |
|
defense response to bacterium
|
GO:0042742 |
119 |
0.940
|
Fly |
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.940
|
Mouse |
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.940
|
Human |
|
cellular response to lipid
|
GO:0071396 |
145 |
0.938
|
Human Mouse |
|
protein import into nucleus translocation
|
GO:0000060 |
12 |
0.938
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.938
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.937
|
Fly |
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.937
|
Mouse |
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.935
|
Mouse |
|
positive regulation of interleukin 10 biosynthetic process
|
GO:0045082 |
1 |
0.934
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.934
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.933
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
10 |
0.930
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.927
|
Mouse |
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.927
|
Mouse |
|
negative regulation of interleukin 12 biosynthetic process
|
GO:0045083 |
1 |
0.926
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.924
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.923
|
Mouse |
|
interleukin 10 biosynthetic process
|
GO:0042091 |
1 |
0.923
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.923
|
Mouse |
|
cytokine production
|
GO:0001816 |
319 |
0.921
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.920
|
Mouse |
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.919
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.918
|
Fly |
|
regionalization
|
GO:0003002 |
337 |
0.912
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.912
|
Mouse |
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.912
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.906
|
Fly |
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.906
|
|
|
skin development
|
GO:0043588 |
220 |
0.904
|
Mouse |
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.895
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.895
|
Fly |
|
circadian rhythm
|
GO:0007623 |
114 |
0.894
|
Mouse |
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.885
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.883
|
Fly |
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.877
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.873
|
Mouse |
|
positive regulation of defense response to virus by host
|
GO:0002230 |
6 |
0.872
|
Fly |
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.871
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.870
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.862
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.860
|
Mouse |
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.853
|
Mouse |
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.852
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.850
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.849
|
|
|
spleen development
|
GO:0048536 |
39 |
0.845
|
Mouse |
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.844
|
Mouse |
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.843
|
|
|
regulation of interleukin 12 biosynthetic process
|
GO:0045075 |
8 |
0.835
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.834
|
Human |
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.831
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.829
|
Mouse |
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.821
|
Mouse |
|
rhythmic process
|
GO:0048511 |
174 |
0.819
|
Mouse |
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.816
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.815
|
Mouse |
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.814
|
Fly |
|
amine metabolic process
|
GO:0009308 |
45 |
0.813
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.811
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.811
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.810
|
Fly |
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.809
|
Mouse |
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.807
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.803
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.802
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.793
|
Mouse |
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.785
|
Human Mouse |
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.785
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.784
|
Fly |
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.775
|
Mouse |
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.773
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.770
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.746
|
Fly |
|
response to peptide
|
GO:1901652 |
136 |
0.737
|
Human Mouse |
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.722
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.717
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.712
|
Mouse |
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.706
|
Fly |
|
interferon gamma production
|
GO:0032609 |
67 |
0.693
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.688
|
Fly |
|
interleukin 12 production
|
GO:0032615 |
32 |
0.687
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.677
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.676
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.670
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.661
|
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
6 |
0.661
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.660
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.656
|
Mouse |
|
response to protozoan
|
GO:0001562 |
28 |
0.642
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.641
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.639
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.632
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.631
|
Human |
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.631
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.621
|
Human |
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.618
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.602
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.600
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.595
|
Mouse Fly |
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.592
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.585
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.585
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
7 |
0.579
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.568
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.564
|
Mouse |
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.552
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.552
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.550
|
Fly |
|
positive regulation of mirna metabolic process
|
GO:2000630 |
1 |
0.549
|
Human |
|
regulation of binding
|
GO:0051098 |
111 |
0.548
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.541
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.533
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.529
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.527
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.526
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.524
|
Fly |
|
liver development
|
GO:0001889 |
66 |
0.524
|
Mouse |
|
protein catabolic process
|
GO:0030163 |
221 |
0.523
|
Mouse |
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.521
|
Mouse |
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
15 |
0.521
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.517
|
Fly |
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
8 |
0.516
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.506
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.504
|
|
|
interleukin 10 production
|
GO:0032613 |
23 |
0.504
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.499
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.498
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.496
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.494
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.492
|
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.491
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.486
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.484
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.484
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.479
|
Mouse |
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
17 |
0.475
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.474
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.474
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.473
|
|
|
regulation of mirna metabolic process
|
GO:2000628 |
4 |
0.471
|
Human |
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.470
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.468
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.466
|
Mouse |
|
regulation of sterol transport
|
GO:0032371 |
17 |
0.462
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.457
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.456
|
|
|
macrophage derived foam cell differentiation
|
GO:0010742 |
6 |
0.443
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.440
|
|
|
positive regulation of growth hormone receptor signaling pathway
|
GO:0060399 |
3 |
0.439
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.429
|
|
|
positive regulation of cholesterol transport
|
GO:0032376 |
9 |
0.425
|
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
10 |
0.423
|
Fly |
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.422
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.414
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.410
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.404
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.400
|
|
|
regulation of cholesterol transport
|
GO:0032374 |
17 |
0.400
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.399
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.399
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.383
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.382
|
Mouse |
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.377
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.377
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.376
|
Fly |
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.374
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.374
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.364
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.360
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.356
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.354
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.349
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.347
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.346
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.342
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.335
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.333
|
Mouse |
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.333
|
|
|
osteoclast proliferation
|
GO:0002158 |
4 |
0.332
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.329
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.325
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.324
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.323
|
Mouse |
|
protein import into nucleus
|
GO:0006606 |
95 |
0.321
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
17 |
0.320
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.319
|
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
15 |
0.313
|
Fly |
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
5 |
0.307
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.307
|
Human |
|
germ cell development
|
GO:0007281 |
185 |
0.306
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.302
|
Mouse |
|
positive regulation of interleukin 12 biosynthetic process
|
GO:0045084 |
6 |
0.300
|
Mouse |
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.300
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.291
|
Fly |
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.291
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.290
|
Fly |
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.290
|
|
|
sterol transport
|
GO:0015918 |
38 |
0.290
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.286
|
|
|
anion transport
|
GO:0006820 |
177 |
0.284
|
|
|
positive regulation of cellular amide metabolic process
|
GO:0034250 |
5 |
0.280
|
Fly |
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.279
|
|
|
negative regulation of mast cell proliferation
|
GO:0070667 |
1 |
0.279
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.277
|
|
|
negative regulation of cytokine production involved in immune response
|
GO:0002719 |
5 |
0.276
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.271
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.270
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
18 |
0.269
|
Fly |
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.269
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.268
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.265
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
2 |
0.265
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.265
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.261
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.258
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.255
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.252
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.246
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.245
|
Fly |
|
response to peptide hormone
|
GO:0043434 |
127 |
0.243
|
Human |
|
amide transport
|
GO:0042886 |
138 |
0.241
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.239
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.238
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.237
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.236
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.236
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.235
|
|
|
mature b cell differentiation involved in immune response
|
GO:0002313 |
9 |
0.232
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.226
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.224
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.221
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.220
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.219
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.218
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.218
|
Human Fly |
|
defense response to virus
|
GO:0051607 |
68 |
0.216
|
Fly |
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.216
|
Human |
|
cytokine secretion
|
GO:0050663 |
72 |
0.215
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.215
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.213
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.212
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.209
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
5 |
0.207
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.206
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.206
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.204
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.202
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.202
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.200
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.197
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.197
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.197
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.196
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.195
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.191
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.190
|
|
|
protein import
|
GO:0017038 |
101 |
0.190
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.188
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.187
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.186
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.185
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
13 |
0.184
|
|
|
regulation of lipid storage
|
GO:0010883 |
20 |
0.184
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.183
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.181
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.179
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.179
|
|
|
cholesterol efflux
|
GO:0033344 |
24 |
0.178
|
|
|
response to exogenous dsrna
|
GO:0043330 |
22 |
0.174
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.174
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.170
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.170
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.169
|
|
|
response to type i interferon
|
GO:0034340 |
12 |
0.168
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.167
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.166
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.163
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.162
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.160
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.158
|
|
|
gland development
|
GO:0048732 |
330 |
0.158
|
Mouse |
|
notch signaling pathway
|
GO:0007219 |
71 |
0.155
|
|
|
positive regulation of antibacterial peptide production
|
GO:0002803 |
1 |
0.155
|
Fly |
|
regulation of dendritic cell cytokine production
|
GO:0002730 |
2 |
0.150
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.150
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.150
|
Fly |
|
chromatin modification
|
GO:0016568 |
187 |
0.148
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.148
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.147
|
|
|
regulation of myd88 dependent toll like receptor signaling pathway
|
GO:0034124 |
2 |
0.147
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.146
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.146
|
|
|
mirna metabolic process
|
GO:0010586 |
10 |
0.146
|
Human |
|
transcription factor import into nucleus
|
GO:0042991 |
26 |
0.145
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.144
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.143
|
Human |
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.141
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.141
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.141
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.135
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.135
|
Fly |
|
interleukin 8 production
|
GO:0032637 |
4 |
0.134
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.133
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.132
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.131
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.131
|
|
|
mature b cell differentiation
|
GO:0002335 |
13 |
0.131
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.129
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.129
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.128
|
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.128
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.126
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.124
|
|
|
gonad development
|
GO:0008406 |
141 |
0.123
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.123
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
4 |
0.123
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.123
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.122
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.121
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.120
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.120
|
Human |
|
ruffle organization
|
GO:0031529 |
16 |
0.120
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.119
|
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
1 |
0.118
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.118
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.116
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.115
|
|
|
negative regulation of interferon beta biosynthetic process
|
GO:0045358 |
1 |
0.113
|
|
|
interferon beta production
|
GO:0032608 |
16 |
0.113
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.112
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.112
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.112
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.112
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.112
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.111
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.111
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.110
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.109
|
Fly |
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.108
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
15 |
0.108
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.107
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.106
|
Human |
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.106
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.106
|
|
|
activation of mapkkk activity
|
GO:0000185 |
1 |
0.105
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.105
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
6 |
0.105
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.105
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
11 |
0.104
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.103
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.103
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.102
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.102
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.101
|
|
|
response to uv b
|
GO:0010224 |
5 |
0.100
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.100
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.100
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.100
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.100
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.100
|
|
|
cellularization
|
GO:0007349 |
1 |
0.100
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.099
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.098
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.097
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.096
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.096
|
|
|
positive regulation of translational initiation by iron
|
GO:0045994 |
2 |
0.095
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.095
|
|
|
response to nicotine
|
GO:0035094 |
6 |
0.095
|
Human |
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.094
|
Human |
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.094
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.094
|
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.092
|
|
|
histone modification
|
GO:0016570 |
159 |
0.092
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.092
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.092
|
|
|
dendritic cell cytokine production
|
GO:0002371 |
3 |
0.092
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.091
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.091
|
|
|
negative regulation of macrophage derived foam cell differentiation
|
GO:0010745 |
1 |
0.091
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.090
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.090
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.090
|
|
|
response to uv
|
GO:0009411 |
44 |
0.089
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.088
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.088
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.088
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.087
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.086
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.085
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.085
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.085
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
26 |
0.085
|
Fly |
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.085
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.084
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.084
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.084
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.083
|
|