|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.693
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.471
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.404
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.381
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.375
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
10 |
0.375
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.374
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.361
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.350
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.344
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.325
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.323
|
Mouse |
|
|
regulation of defense response to fungus
|
GO:1900150 |
1 |
0.322
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.318
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.310
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.307
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.291
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.265
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.255
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.253
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.250
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.241
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.239
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.223
|
|
|
|
positive regulation of nuclear transcribed mrna poly a tail shortening
|
GO:0060213 |
4 |
0.217
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.214
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.213
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.210
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.205
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.199
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.191
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.184
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.179
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.175
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.174
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.168
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.166
|
|
|
|
regulation of neutrophil mediated killing of gram negative bacterium
|
GO:0070951 |
1 |
0.157
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.157
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.155
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.153
|
|
|
|
nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070427 |
5 |
0.150
|
|
|
|
positive regulation of neutrophil mediated killing of symbiont cell
|
GO:0070961 |
1 |
0.149
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.148
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.146
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.145
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.144
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.137
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.137
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.136
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.134
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.126
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.123
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.121
|
Mouse |
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
0.121
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.120
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.118
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.116
|
|
|
|
positive regulation of mrna 3 end processing
|
GO:0031442 |
5 |
0.115
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.112
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.111
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.111
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.109
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.107
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.106
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.106
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.103
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.101
|
|
|
|
regulation of hematopoietic stem cell proliferation
|
GO:1902033 |
3 |
0.101
|
|
|
|
neutrophil mediated killing of gram negative bacterium
|
GO:0070945 |
4 |
0.099
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.098
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.095
|
|
|
|
positive regulation of neutrophil mediated cytotoxicity
|
GO:0070960 |
1 |
0.095
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.093
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.091
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.090
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.090
|
|
|
|
positive regulation of interleukin 10 biosynthetic process
|
GO:0045082 |
1 |
0.089
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.085
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.085
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.081
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.081
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.080
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.080
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.079
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.078
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.077
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.077
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.077
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.076
|
|
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.076
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.076
|
Mouse |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.075
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.074
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.074
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.074
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.074
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.073
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.073
|
|
|
|
brain segmentation
|
GO:0035284 |
3 |
0.073
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.072
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.071
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.069
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.069
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.069
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.069
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.068
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.068
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.068
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.067
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.067
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.067
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.067
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.066
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.066
|
|
|
|
positive regulation of killing of cells of other organism
|
GO:0051712 |
3 |
0.065
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.064
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.064
|
Mouse |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.064
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.064
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.063
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.063
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.063
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.063
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.062
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.062
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.062
|
Mouse |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.062
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.061
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.061
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.061
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.061
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.060
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.060
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.059
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.059
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.059
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.058
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.058
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.058
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.058
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.057
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.057
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.057
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.056
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.055
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.055
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.055
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.055
|
Mouse |
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.054
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.054
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.054
|
|
|
|
wound healing involved in inflammatory response
|
GO:0002246 |
4 |
0.054
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.054
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.053
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.053
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.053
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.053
|
Mouse |
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.053
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.053
|
|
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
1 |
0.053
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.053
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.053
|
Mouse |
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.053
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.052
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.052
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.052
|
|
|
|
regulation of neutrophil mediated killing of symbiont cell
|
GO:0070949 |
2 |
0.052
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.052
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.052
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.051
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.051
|
|
|
|
spongiotrophoblast layer development
|
GO:0060712 |
15 |
0.050
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.050
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.050
|
|
|
|
positive regulation of mrna catabolic process
|
GO:0061014 |
5 |
0.050
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.050
|
|
|
|
regulation of mrna catabolic process
|
GO:0061013 |
6 |
0.050
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.050
|
Mouse |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.049
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.049
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.049
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.049
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.049
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.048
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.047
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.047
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.047
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.047
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.047
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.046
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.046
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.046
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.046
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.045
|
|
|
|
regulation of neutrophil mediated cytotoxicity
|
GO:0070948 |
2 |
0.045
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.045
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.045
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.045
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.044
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.044
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.044
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.044
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.044
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.044
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.043
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.043
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.043
|
Mouse |
|
|
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay
|
GO:1900153 |
5 |
0.043
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.043
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.043
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.043
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.043
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.042
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity involved in g2 m transition of mitotic cell cycle
|
GO:0031660 |
1 |
0.042
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.042
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.042
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.042
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.041
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.041
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.041
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.041
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.041
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.041
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.041
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.040
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.040
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.040
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.040
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.040
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.039
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.039
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.039
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.039
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.039
|
|
|
|
central nervous system segmentation
|
GO:0035283 |
3 |
0.039
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.039
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.038
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.038
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.038
|
|
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
1 |
0.038
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.038
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.038
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.037
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.037
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.037
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.037
|
|
|
|
positive regulation of hematopoietic stem cell proliferation
|
GO:1902035 |
2 |
0.037
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.037
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.037
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.036
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.036
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.036
|
|
|
|
response to purine containing compound
|
GO:0014074 |
28 |
0.036
|
|
|
|
negative regulation of ovulation
|
GO:0060280 |
1 |
0.036
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.036
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.036
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.036
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.036
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
4 |
0.036
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.036
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.036
|
|
|
|
vitellogenesis
|
GO:0007296 |
2 |
0.035
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.035
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.034
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.034
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.034
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.034
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.034
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.034
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.034
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.033
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.033
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.033
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.033
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.032
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.032
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.032
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.032
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.032
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.032
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.032
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.032
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.032
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.032
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.032
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.031
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.031
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.031
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.031
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.031
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.031
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.031
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.031
|
Mouse |
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.031
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.031
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.031
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.031
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.030
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.030
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.030
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.030
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.030
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.030
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.030
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.030
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.029
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.029
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.029
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.029
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.029
|
|
|
|
translation
|
GO:0006412 |
93 |
0.029
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.029
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
41 |
0.029
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.029
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.029
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.029
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.029
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.029
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.029
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.029
|
|
|
|
negative regulation of protein kinase activity by regulation of protein phosphorylation
|
GO:0044387 |
2 |
0.029
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.029
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.028
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.028
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.028
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.028
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.028
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.028
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.028
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.028
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061418 |
2 |
0.028
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.027
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.027
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.027
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.027
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.027
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.027
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.027
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.027
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.027
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.027
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.027
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.027
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.027
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.027
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.027
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.027
|
|
|
|
defense response to fungus
|
GO:0050832 |
12 |
0.026
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.026
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.026
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.026
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.026
|
|
|
|
cellular response to follicle stimulating hormone stimulus
|
GO:0071372 |
1 |
0.026
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.026
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.026
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.026
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.026
|
|
|
|
positive regulation of neutrophil mediated killing of fungus
|
GO:0070965 |
1 |
0.026
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.026
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.025
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.025
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.025
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.025
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.025
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.025
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.025
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.025
|
|
|
|
regulation of neutrophil mediated killing of fungus
|
GO:0070953 |
1 |
0.025
|
|
|
|
negative regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902443 |
3 |
0.025
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.025
|
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.025
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.025
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.025
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.025
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.025
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.024
|
|
|
|
regulation of mesenchymal cell apoptotic process involved in metanephros development
|
GO:1900211 |
4 |
0.024
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.024
|
|
|
|
neutrophil mediated killing of symbiont cell
|
GO:0070943 |
8 |
0.024
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.024
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.024
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.024
|
|
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
4 |
0.024
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.024
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.024
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.024
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.024
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.024
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.024
|
|
|
|
follicular dendritic cell differentiation
|
GO:0002268 |
2 |
0.024
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.024
|
|
|
|
transforming growth factor beta2 production
|
GO:0032906 |
2 |
0.024
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.024
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.023
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.023
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.023
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.023
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.023
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.023
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.023
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.023
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.023
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.023
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.023
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.023
|
|
|
|
regulation of killing of cells of other organism
|
GO:0051709 |
4 |
0.022
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.022
|
|
|
|
connective tissue replacement involved in inflammatory response wound healing
|
GO:0002248 |
3 |
0.022
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.022
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.022
|
|
|
|
axon regeneration
|
GO:0031103 |
12 |
0.022
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.022
|
|
|
|
response to catecholamine
|
GO:0071869 |
4 |
0.022
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.022
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.022
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.022
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.022
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.022
|
|
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.022
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.022
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.022
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.022
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.022
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.022
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.022
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.022
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.022
|
|
|
|
mrna processing
|
GO:0006397 |
63 |
0.022
|
|
|
|
adrenal cortex development
|
GO:0035801 |
2 |
0.022
|
|
|
|
nuclear transcribed mrna poly a tail shortening
|
GO:0000289 |
7 |
0.022
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.022
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.021
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
10 |
0.021
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.021
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.021
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.021
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.021
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
4 |
0.021
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.021
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.021
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.021
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
26 |
0.021
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.021
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.021
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
32 |
0.021
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.021
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.021
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.021
|
|
|
|
rna 3 end processing
|
GO:0031123 |
20 |
0.021
|
|
|
|
chorio allantoic fusion
|
GO:0060710 |
8 |
0.021
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.021
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.021
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.021
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.021
|
|
|
|
response to copper ion
|
GO:0046688 |
3 |
0.021
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.021
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.020
|
Mouse |
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.020
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.020
|
Mouse |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.020
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
22 |
0.020
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.020
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.020
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.020
|
Mouse |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.020
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.020
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.020
|
|
|
|
rhombomere 5 development
|
GO:0021571 |
4 |
0.020
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.020
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.020
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.020
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.020
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.020
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.020
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.020
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.020
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.020
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.020
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.020
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.020
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.020
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.020
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.020
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.020
|
|
|
|
cellular response to gonadotropin stimulus
|
GO:0071371 |
4 |
0.020
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.020
|
|
|
|
regulation of mrna 3 end processing
|
GO:0031440 |
6 |
0.020
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.020
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.020
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.020
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.020
|
|
|
|
regulation of respiratory burst involved in inflammatory response
|
GO:0060264 |
2 |
0.020
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.019
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.019
|
|
