Mus musculus

16 known processes

Niacr1

niacin receptor 1

(Aliases: HM74,PUMA-G,Pumag,mHM74b,Gpr109b,Gpr109a)

Niacr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of fungus GO:0016046 2 0.558
cytokine production GO:0001816 319 0.477
Mouse
defense response to other organism GO:0098542 197 0.436
Mouse
protein secretion GO:0009306 111 0.424
Mouse
positive regulation of cytokine production GO:0001819 174 0.414
Mouse
leukocyte mediated immunity GO:0002443 174 0.411
myeloid leukocyte mediated immunity GO:0002444 42 0.393
positive regulation of defense response GO:0031349 124 0.380
Mouse
neutrophil mediated killing of symbiont cell GO:0070943 8 0.367
regulation of cell activation GO:0050865 289 0.299
adaptive immune response GO:0002250 155 0.291
t cell activation GO:0042110 289 0.279
Mouse
leukocyte differentiation GO:0002521 342 0.275
Mouse
regulation of cytokine production GO:0001817 266 0.273
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.267
Mouse
regulation of secretion by cell GO:1903530 249 0.262
Mouse Rat
immune effector process GO:0002252 321 0.261
Mouse
positive regulation of cytokine biosynthetic process GO:0042108 40 0.245
cellular response to lipopolysaccharide GO:0071222 77 0.241
response to molecule of bacterial origin GO:0002237 143 0.237
Mouse
negative regulation of immune system process GO:0002683 209 0.237
inflammatory response GO:0006954 244 0.234
Mouse
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.229
regulation of lymphocyte activation GO:0051249 240 0.223
regulation of defense response GO:0031347 233 0.222
Mouse
defense response to bacterium GO:0042742 119 0.212
regulation of innate immune response GO:0045088 91 0.205
regulation of protein localization GO:0032880 231 0.202
Mouse
regulation of establishment of protein localization GO:0070201 181 0.200
Mouse
regulation of response to wounding GO:1903034 189 0.186
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.183
Mouse Rat
regulation of secretion GO:0051046 274 0.183
Mouse Rat
interspecies interaction between organisms GO:0044419 83 0.169
activation of innate immune response GO:0002218 56 0.166
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.164
alpha beta t cell activation GO:0046631 91 0.161
cellular response to cytokine stimulus GO:0071345 189 0.158
production of molecular mediator of immune response GO:0002440 103 0.152
Mouse
interferon gamma production GO:0032609 67 0.150
Mouse
innate immune response GO:0045087 157 0.148
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.147
striated muscle tissue development GO:0014706 293 0.145
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.144
immune response activating signal transduction GO:0002757 116 0.143
positive regulation of immune effector process GO:0002699 107 0.140
Mouse
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.139
regulation of leukocyte mediated immunity GO:0002703 104 0.136
regulation of protein transport GO:0051223 163 0.135
Mouse
regulation of chemokine production GO:0032642 30 0.135
Mouse
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.134
regulation of inflammatory response GO:0050727 147 0.131
Mouse
positive regulation of cytokine secretion GO:0050715 41 0.129
regulation of protein secretion GO:0050708 82 0.128
Mouse
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.127
immune response regulating signaling pathway GO:0002764 125 0.123
neutrophil mediated cytotoxicity GO:0070942 8 0.123
response to lipopolysaccharide GO:0032496 128 0.120
Mouse
lymphocyte mediated immunity GO:0002449 139 0.119
neutrophil chemotaxis GO:0030593 36 0.116
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.116
positive regulation of leukocyte mediated immunity GO:0002705 70 0.113
regulation of t cell activation GO:0050863 170 0.113
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.113
regulation of tumor necrosis factor production GO:0032680 49 0.112
regulation of adaptive immune response GO:0002819 90 0.107
positive regulation of interferon gamma production GO:0032729 39 0.107
positive regulation of protein secretion GO:0050714 52 0.107
Mouse
detection of yeast GO:0001879 2 0.106
cytokine production involved in immune response GO:0002367 34 0.101
Mouse
t helper 2 cell cytokine production GO:0035745 4 0.101
interaction with symbiont GO:0051702 14 0.099
regulation of protein kinase activity GO:0045859 232 0.098
cytokine secretion GO:0050663 72 0.095
Mouse
positive regulation of leukocyte differentiation GO:1902107 86 0.095
muscle fiber development GO:0048747 76 0.094
positive regulation of protein transport GO:0051222 93 0.094
Mouse
cytokine metabolic process GO:0042107 71 0.092
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.090
regulation of hormone levels GO:0010817 211 0.090
Mouse Rat
membrane organization GO:0061024 245 0.089
nitrogen compound transport GO:0071705 271 0.087
Mouse
regulation of defense response to bacterium GO:1900424 3 0.087
myotube cell development GO:0014904 60 0.086
divalent inorganic cation transport GO:0072511 178 0.085
defense response to virus GO:0051607 68 0.084
Mouse
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.083
disruption by host of symbiont cells GO:0051852 11 0.083
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.083
regulation of cytokine biosynthetic process GO:0042035 59 0.083
cation transport GO:0006812 399 0.083
positive regulation of innate immune response GO:0045089 80 0.081
lymphocyte proliferation GO:0046651 164 0.081
leukocyte mediated cytotoxicity GO:0001909 62 0.080
neutrophil mediated immunity GO:0002446 19 0.080
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.080
disruption of cells of other organism GO:0044364 13 0.078
myeloid leukocyte activation GO:0002274 83 0.078
regulation of cytokine secretion GO:0050707 61 0.078
granulocyte migration GO:0097530 43 0.077
t cell differentiation GO:0030217 174 0.075
lymphocyte activation involved in immune response GO:0002285 93 0.075
Mouse
cytokine biosynthetic process GO:0042089 68 0.075
lymphocyte differentiation GO:0030098 242 0.073
muscle cell development GO:0055001 133 0.072
regulation of skeletal muscle fiber development GO:0048742 36 0.071
regulation of muscle tissue development GO:1901861 97 0.070
cytokine mediated signaling pathway GO:0019221 115 0.069
natural killer cell chemotaxis GO:0035747 1 0.068
chemotaxis GO:0006935 247 0.068
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.067
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.067
cellular ion homeostasis GO:0006873 165 0.067
Mouse
tumor necrosis factor production GO:0032640 50 0.067
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.067
sequestering of calcium ion GO:0051208 18 0.066
regulation of myotube differentiation GO:0010830 62 0.065
t helper 1 cell cytokine production GO:0035744 1 0.065
skeletal muscle organ development GO:0060538 163 0.065
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.064
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.063
neutrophil mediated killing of bacterium GO:0070944 6 0.062
adiponectin secretion GO:0070162 2 0.062
Rat
regulation of reactive oxygen species metabolic process GO:2000377 40 0.062
negative regulation of cell activation GO:0050866 111 0.062
reactive oxygen species metabolic process GO:0072593 84 0.061
cellular response to molecule of bacterial origin GO:0071219 83 0.061
skeletal muscle fiber development GO:0048741 58 0.061
cellular amine metabolic process GO:0044106 44 0.060
cellular response to biotic stimulus GO:0071216 92 0.060
regulation of t cell differentiation GO:0045580 83 0.060
negative regulation of leukocyte mediated immunity GO:0002704 29 0.060
leukocyte chemotaxis GO:0030595 69 0.059
regulation of multi organism process GO:0043900 111 0.058
t cell mediated immunity GO:0002456 50 0.058
regulation of kinase activity GO:0043549 249 0.058
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.058
regulation of t helper 2 cell cytokine production GO:2000551 3 0.057
negative regulation of lymphocyte activation GO:0051250 91 0.057
neutrophil migration GO:1990266 37 0.056
positive regulation of lymphocyte activation GO:0051251 140 0.055
cell killing GO:0001906 67 0.055
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.055
metal ion homeostasis GO:0055065 189 0.054
Mouse
inflammatory response to wounding GO:0090594 4 0.054
regulation of monocyte chemotaxis GO:0090025 3 0.054
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.054
regulation of leukocyte proliferation GO:0070663 121 0.053
cell activation involved in immune response GO:0002263 126 0.053
Mouse
cellular ketone metabolic process GO:0042180 84 0.052
cation homeostasis GO:0055080 212 0.052
Mouse
antigen processing and presentation GO:0019882 47 0.052
regulation of vesicle mediated transport GO:0060627 139 0.052
detection of biotic stimulus GO:0009595 10 0.051
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.051
calcium ion transport GO:0006816 159 0.051
killing by host of symbiont cells GO:0051873 11 0.051
interleukin 1 beta production GO:0032611 30 0.050
Mouse
positive regulation of lymphocyte differentiation GO:0045621 61 0.050
myeloid cell differentiation GO:0030099 233 0.050
cellular homeostasis GO:0019725 240 0.050
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.050
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.050
reactive nitrogen species metabolic process GO:2001057 0 0.049
t helper cell differentiation GO:0042093 28 0.049
regulation of lymphocyte differentiation GO:0045619 107 0.049
cellular amino acid metabolic process GO:0006520 103 0.049
cellular divalent inorganic cation homeostasis GO:0072503 127 0.048
Mouse
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.047
regulation of leukocyte differentiation GO:1902105 159 0.047
maintenance of location GO:0051235 89 0.047
positive regulation of t cell activation GO:0050870 101 0.046
chemokine production GO:0032602 34 0.046
Mouse
myoblast differentiation GO:0045445 52 0.046
regulation of t cell proliferation GO:0042129 92 0.045
killing of cells of other organism GO:0031640 13 0.045
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.045
myeloid leukocyte differentiation GO:0002573 119 0.045
divalent metal ion transport GO:0070838 172 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.044
mature natural killer cell chemotaxis GO:0035782 1 0.044
myotube differentiation GO:0014902 105 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
acute inflammatory response GO:0002526 41 0.044
Mouse
positive regulation of inflammatory response GO:0050729 47 0.044
Mouse
endocytosis GO:0006897 168 0.043
positive regulation of secretion GO:0051047 130 0.043
Mouse Rat
positive regulation of t cell differentiation GO:0045582 52 0.043
cell chemotaxis GO:0060326 81 0.043
regulation of ion transport GO:0043269 215 0.043
regulation of homeostatic process GO:0032844 182 0.043
Human
negative regulation of cell proliferation GO:0008285 296 0.043
positive regulation of cell activation GO:0050867 158 0.042
interleukin 12 secretion GO:0072610 3 0.042
positive regulation of transferase activity GO:0051347 167 0.042
negative regulation of muscle cell differentiation GO:0051148 33 0.042
cellular calcium ion homeostasis GO:0006874 119 0.042
Mouse
positive regulation of killing of cells of other organism GO:0051712 3 0.042
regulation of map kinase activity GO:0043405 120 0.042
regulation of cell migration GO:0030334 219 0.042
Mouse
regulation of stress activated mapk cascade GO:0032872 69 0.042
positive regulation of b cell chemotaxis GO:2000538 2 0.041
negative regulation of secretion GO:0051048 61 0.041
Mouse
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.041
dendritic cell differentiation GO:0097028 26 0.041
Mouse
granulocyte chemotaxis GO:0071621 39 0.041
cellular metal ion homeostasis GO:0006875 151 0.041
Mouse
amide transport GO:0042886 138 0.041
Mouse
muscle tissue development GO:0060537 308 0.040
b cell mediated immunity GO:0019724 71 0.040
positive regulation of intracellular transport GO:0032388 70 0.040
pattern recognition receptor signaling pathway GO:0002221 47 0.040
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.040
t cell proliferation GO:0042098 120 0.039
regulation of defense response to fungus GO:1900150 1 0.039
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.039
negative regulation of cytokine production GO:0001818 84 0.039
negative regulation of multi organism process GO:0043901 68 0.039
negative regulation of mast cell degranulation GO:0043305 4 0.039
modification of morphology or physiology of other organism GO:0035821 18 0.039
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.038
muscle cell differentiation GO:0042692 261 0.038
leukocyte proliferation GO:0070661 172 0.038
Mouse
cellular response to peptidoglycan GO:0071224 4 0.038
serotonin secretion by mast cell GO:0002552 1 0.038
calcium ion homeostasis GO:0055074 127 0.037
Mouse
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.037
detection of molecule of bacterial origin GO:0032490 2 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.037
detection of stimulus GO:0051606 84 0.037
positive regulation of chemokine production GO:0032722 22 0.037
Mouse
regulation of endocytosis GO:0030100 69 0.036
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.036
striated muscle cell development GO:0055002 125 0.036
response to organic cyclic compound GO:0014070 198 0.036
eosinophil migration GO:0072677 3 0.036
regulation of dendritic cell chemotaxis GO:2000508 1 0.036
cellular chemical homeostasis GO:0055082 215 0.036
Mouse
regulation of interleukin 8 production GO:0032677 3 0.036
defense response to fungus GO:0050832 12 0.035
mapk cascade GO:0000165 281 0.035
Mouse
gland development GO:0048732 330 0.035
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.035
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.035
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.035
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.034
positive regulation of secretion by cell GO:1903532 114 0.034
Mouse Rat
myeloid leukocyte migration GO:0097529 57 0.034
positive regulation of response to wounding GO:1903036 66 0.034
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.034
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.034
cytosolic calcium ion transport GO:0060401 48 0.034
negative regulation of myoblast differentiation GO:0045662 18 0.034
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.034
negative regulation of macrophage apoptotic process GO:2000110 3 0.033
blood vessel morphogenesis GO:0048514 285 0.033
apoptotic signaling pathway GO:0097190 306 0.033
regulation of ion homeostasis GO:2000021 64 0.033
regulation of transferase activity GO:0051338 263 0.033
inflammatory response to antigenic stimulus GO:0002437 30 0.033
positive regulation of phagocytosis GO:0050766 26 0.033
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.033
regulation of lymphocyte proliferation GO:0050670 117 0.032
glycoprotein metabolic process GO:0009100 116 0.032
mature dendritic cell differentiation GO:0097029 3 0.032
Mouse
interleukin 8 production GO:0032637 4 0.032
cell type specific apoptotic process GO:0097285 268 0.032
Human
negative regulation of adaptive immune response GO:0002820 25 0.032
negative regulation of t cell proliferation GO:0042130 38 0.032
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.032
regulation of b cell chemotaxis GO:2000537 2 0.032
wound healing involved in inflammatory response GO:0002246 4 0.032
organic anion transport GO:0015711 137 0.031
positive regulation of protein phosphorylation GO:0001934 242 0.031
response to molecule of fungal origin GO:0002238 4 0.031
angiogenesis GO:0001525 201 0.031
multicellular organismal homeostasis GO:0048871 164 0.031
Mouse
regulation of cellular response to stress GO:0080135 159 0.031
syncytium formation by plasma membrane fusion GO:0000768 42 0.031
immunoglobulin production in mucosal tissue GO:0002426 3 0.030
negative regulation of t cell activation GO:0050868 65 0.030
divalent inorganic cation homeostasis GO:0072507 138 0.030
Mouse
regulation of b cell mediated immunity GO:0002712 37 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
negative regulation of immune effector process GO:0002698 55 0.030
cytoplasmic transport GO:0016482 234 0.030
regulation of killing of cells of other organism GO:0051709 4 0.029
negative regulation of mapk cascade GO:0043409 65 0.029
positive regulation of protein kinase activity GO:0045860 144 0.029
eosinophil degranulation GO:0043308 1 0.029
positive regulation of jnk cascade GO:0046330 46 0.029
leukocyte migration GO:0050900 124 0.029
regulation of angiogenesis GO:0045765 81 0.029
regulation of interferon gamma production GO:0032649 57 0.029
cell recognition GO:0008037 83 0.029
regulation of cytoplasmic transport GO:1903649 112 0.029
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.028
positive regulation of interleukin 6 production GO:0032755 37 0.028
positive regulation of tumor necrosis factor production GO:0032760 30 0.028
negative regulation of serotonin secretion GO:0014063 2 0.028
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.028
positive regulation of neutrophil chemotaxis GO:0090023 12 0.028
i kappab kinase nf kappab signaling GO:0007249 85 0.028
positive regulation of chemokine biosynthetic process GO:0045080 6 0.028
activation of immune response GO:0002253 138 0.028
wound healing GO:0042060 157 0.027
Mouse
regulation of membrane potential GO:0042391 192 0.027
Mouse
positive regulation of b cell mediated immunity GO:0002714 26 0.027
exocytosis GO:0006887 121 0.027
humoral immune response GO:0006959 57 0.027
stress activated protein kinase signaling cascade GO:0031098 81 0.027
regulation of striated muscle cell differentiation GO:0051153 81 0.027
regulation of neutrophil chemotaxis GO:0090022 14 0.027
eosinophil activation involved in immune response GO:0002278 1 0.027
negative regulation of secretion by cell GO:1903531 54 0.027
Mouse
neutrophil mediated killing of fungus GO:0070947 3 0.027
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.027
sequestering of metal ion GO:0051238 19 0.027
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.027
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.027
Mouse
regulation of dendritic cell dendrite assembly GO:2000547 2 0.026
positive regulation of interleukin 12 production GO:0032735 21 0.026
regulation of intracellular transport GO:0032386 159 0.026
glycoprotein biosynthetic process GO:0009101 89 0.026
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.026
regulation of natural killer cell chemotaxis GO:2000501 1 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
positive regulation of leukocyte proliferation GO:0070665 73 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
positive regulation of stress activated mapk cascade GO:0032874 48 0.026
innate immune response activating signal transduction GO:0002758 50 0.026
regulation of myoblast differentiation GO:0045661 29 0.026
regulation of cell killing GO:0031341 40 0.026
peptidyl amino acid modification GO:0018193 336 0.026
regulation of jnk cascade GO:0046328 62 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
Mouse
rho protein signal transduction GO:0007266 32 0.026
Mouse
regulation of phagocytosis GO:0050764 33 0.025
reactive oxygen species biosynthetic process GO:1903409 8 0.025
epithelial tube morphogenesis GO:0060562 303 0.025
regulation of acute inflammatory response GO:0002673 27 0.025
Mouse
detection of other organism GO:0098543 8 0.025
regulation of immunoglobulin mediated immune response GO:0002889 37 0.025
regulation of chemokine biosynthetic process GO:0045073 8 0.025
regulation of t helper 1 cell cytokine production GO:2000554 1 0.025
positive regulation of apoptotic process GO:0043065 217 0.025
Human
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.024
positive regulation of cell killing GO:0031343 33 0.024
jnk cascade GO:0007254 72 0.024
modification by host of symbiont morphology or physiology GO:0051851 12 0.024
positive regulation of map kinase activity GO:0043406 84 0.024
calcium mediated signaling GO:0019722 46 0.024
antibacterial peptide biosynthetic process GO:0002780 2 0.023
regulation of cell cycle GO:0051726 281 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
regulation of protein processing GO:0070613 96 0.023
regulation of action potential GO:0098900 4 0.023
Mouse
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.023
cellular response to lipid GO:0071396 145 0.023
Mouse
hematopoietic stem cell proliferation GO:0071425 13 0.023
response to organonitrogen compound GO:0010243 246 0.023
Mouse
immunoglobulin production GO:0002377 73 0.023
single organism cell adhesion GO:0098602 156 0.022
anion transport GO:0006820 177 0.022
Mouse
epithelial cell proliferation GO:0050673 174 0.022
sensory perception GO:0007600 245 0.022
amine metabolic process GO:0009308 45 0.022
ion transmembrane transport GO:0034220 361 0.022
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.022
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.022
immunoglobulin mediated immune response GO:0016064 69 0.022
positive regulation of ion transport GO:0043270 65 0.022
regulation of cell motility GO:2000145 236 0.022
Mouse
t cell activation involved in immune response GO:0002286 43 0.021
Mouse
regulation of t cell extravasation GO:2000407 3 0.021
syncytium formation GO:0006949 43 0.021
interleukin 1 production GO:0032612 31 0.021
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
nitric oxide biosynthetic process GO:0006809 25 0.021
homeostasis of number of cells GO:0048872 210 0.021
Human Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
negative regulation of striated muscle cell differentiation GO:0051154 14 0.021
macromolecule catabolic process GO:0009057 281 0.021
nucleotide metabolic process GO:0009117 332 0.021
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.021
carboxylic acid transport GO:0046942 100 0.020
cdc42 protein signal transduction GO:0032488 0 0.020
mitotic cell cycle process GO:1903047 159 0.020
positive regulation of lymphocyte proliferation GO:0050671 70 0.020
nuclear transport GO:0051169 139 0.020
positive regulation of jun kinase activity GO:0043507 30 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.020
dendritic cell dendrite assembly GO:0097026 2 0.020
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.020
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.020
positive regulation of t cell extravasation GO:2000409 2 0.020
regulation of leukocyte apoptotic process GO:2000106 56 0.020
Human
negative regulation of intracellular signal transduction GO:1902532 167 0.020
regulation of type 2 immune response GO:0002828 18 0.020
cell adhesion GO:0007155 329 0.020
negative regulation of homeostatic process GO:0032845 71 0.020
ras protein signal transduction GO:0007265 77 0.020
Mouse
single organismal cell cell adhesion GO:0016337 131 0.020
protein localization to organelle GO:0033365 185 0.020
negative regulation of defense response GO:0031348 77 0.020
positive regulation of chemokine secretion GO:0090197 4 0.020
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.020
cd4 positive alpha beta t cell activation GO:0035710 45 0.019
positive regulation of t cell costimulation GO:2000525 2 0.019
phagocytosis GO:0006909 66 0.019
positive regulation of endocytosis GO:0045807 42 0.019
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.019
regulation of immunoglobulin production GO:0002637 42 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
positive regulation of cell death GO:0010942 224 0.019
Human
positive regulation of immunological synapse formation GO:2000522 1 0.019
natural killer cell activation GO:0030101 44 0.019
cation transmembrane transport GO:0098655 266 0.019
macrophage chemotaxis GO:0048246 14 0.019
release of sequestered calcium ion into cytosol GO:0051209 42 0.019
interleukin 6 production GO:0032635 58 0.019
regulation of antimicrobial humoral response GO:0002759 3 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
t helper 1 type immune response GO:0042088 25 0.019
negative regulation of molecular function GO:0044092 258 0.019
astrocyte cell migration GO:0043615 3 0.019
cytosolic calcium ion homeostasis GO:0051480 70 0.019
Mouse
organic acid transport GO:0015849 101 0.019
t cell differentiation involved in immune response GO:0002292 30 0.018
hair cycle GO:0042633 90 0.018
regulation of interleukin 6 production GO:0032675 55 0.018
detection of peptidoglycan GO:0032499 1 0.018
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.018
type 2 immune response GO:0042092 23 0.018
cellular response to organic cyclic compound GO:0071407 87 0.018
regulation of jun kinase activity GO:0043506 40 0.018
regulation of t cell mediated immunity GO:0002709 34 0.018
action potential GO:0001508 78 0.018
Mouse
protein maturation GO:0051604 176 0.018
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.018
regulation of interleukin 2 production GO:0032663 28 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
b cell activation GO:0042113 161 0.017
antimicrobial peptide production GO:0002775 2 0.017
transmembrane transport GO:0055085 412 0.017
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.017
positive regulation of cytoplasmic transport GO:1903651 40 0.017
positive regulation of protein modification process GO:0031401 299 0.017
positive regulation of interleukin 8 production GO:0032757 2 0.017
regulation of mapk cascade GO:0043408 248 0.017
Mouse
negative regulation of protein modification process GO:0031400 163 0.017
alpha beta t cell proliferation GO:0046633 21 0.017
detection of bacterium GO:0016045 7 0.017
alpha beta t cell activation involved in immune response GO:0002287 31 0.017
positive regulation of type 2 immune response GO:0002830 9 0.017
ameboidal type cell migration GO:0001667 128 0.017
regulation of renin secretion into blood stream GO:1900133 4 0.017
Mouse
positive regulation of striated muscle cell differentiation GO:0051155 35 0.017
protein processing GO:0016485 163 0.017
regulation of thymocyte migration GO:2000410 2 0.016
regulation of immunological synapse formation GO:2000520 2 0.016
positive regulation of epithelial cell proliferation GO:0050679 68 0.016
interleukin 12 production GO:0032615 32 0.016
t cell extravasation GO:0072683 4 0.016
regulation of t cell costimulation GO:2000523 2 0.016
regulation of protein catabolic process GO:0042176 108 0.016
positive regulation of calcium ion transport GO:0051928 27 0.016
negative regulation of protein transport GO:0051224 46 0.016
Mouse
negative regulation of synapse assembly GO:0051964 3 0.016
regulation of alpha beta t cell activation GO:0046634 53 0.016
antimicrobial peptide biosynthetic process GO:0002777 2 0.016
myeloid cell activation involved in immune response GO:0002275 34 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
Mouse
regulation of peptidase activity GO:0052547 96 0.016
positive regulation of interleukin 18 production GO:0032741 2 0.016
chemokine metabolic process GO:0050755 10 0.016
stress activated mapk cascade GO:0051403 80 0.016
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.016
organic acid biosynthetic process GO:0016053 86 0.016
regulation of cell projection assembly GO:0060491 38 0.016
Mouse
regulation of body fluid levels GO:0050878 162 0.016
Mouse
skin development GO:0043588 220 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
Rat
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.015
negative regulation of proteolysis GO:0045861 74 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
interleukin 18 production GO:0032621 4 0.015

Niacr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
acquired immunodeficiency syndrome DOID:635 0 0.050
disease by infectious agent DOID:0050117 0 0.050
viral infectious disease DOID:934 0 0.050
human immunodeficiency virus infectious disease DOID:526 0 0.050
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.016