Mus musculus

0 known processes

Nkx1-2

NK1 transcription factor related, locus 2 (Drosophila)

(Aliases: Nkx-1.1,Nkx-1.2,Sax1)

Nkx1-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spinal cord development GO:0021510 81 0.946
positive regulation of cell development GO:0010720 237 0.884
epithelial tube morphogenesis GO:0060562 303 0.855
ventral spinal cord interneuron fate commitment GO:0060579 14 0.789
forebrain generation of neurons GO:0021872 63 0.783
forebrain development GO:0030900 302 0.774
central nervous system neuron differentiation GO:0021953 162 0.749
stem cell differentiation GO:0048863 268 0.746
paraxial mesodermal cell differentiation GO:0048342 2 0.742
epithelial tube formation GO:0072175 130 0.738
diencephalon development GO:0021536 63 0.732
cell fate specification GO:0001708 72 0.708
forebrain neuron differentiation GO:0021879 52 0.704
mesenchymal cell differentiation GO:0048762 107 0.703
stem cell development GO:0048864 219 0.701
embryonic epithelial tube formation GO:0001838 130 0.698
cell fate determination GO:0001709 32 0.680
Mouse Fly
muscle cell differentiation GO:0042692 261 0.675
Fly
neural tube development GO:0021915 160 0.673
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.662
pallium development GO:0021543 120 0.661
hindbrain development GO:0030902 128 0.657
mesenchyme development GO:0060485 152 0.647
somatotropin secreting cell differentiation GO:0060126 4 0.647
cellular amine metabolic process GO:0044106 44 0.641
bmp signaling pathway GO:0030509 93 0.636
auditory receptor cell fate determination GO:0042668 3 0.629
developmental programmed cell death GO:0010623 41 0.629
cell fate commitment GO:0045165 210 0.629
Mouse Fly
ion transmembrane transport GO:0034220 361 0.627
epithelial cell proliferation GO:0050673 174 0.624
regulation of cellular ketone metabolic process GO:0010565 66 0.619
astrocyte fate commitment GO:0060018 4 0.617
regulation of cellular amino acid metabolic process GO:0006521 5 0.611
limbic system development GO:0021761 72 0.610
cell differentiation in spinal cord GO:0021515 53 0.610
aortic valve morphogenesis GO:0003180 4 0.588
regulation of organ morphogenesis GO:2000027 144 0.587
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.586
cardiocyte differentiation GO:0035051 87 0.578
cellular ketone metabolic process GO:0042180 84 0.565
sensory organ morphogenesis GO:0090596 242 0.556
kidney development GO:0001822 213 0.551
cerebellum formation GO:0021588 1 0.551
mesoderm development GO:0007498 100 0.545
regulation of epithelial cell proliferation GO:0050678 141 0.543
skeletal system morphogenesis GO:0048705 203 0.543
homeostasis of number of cells GO:0048872 210 0.540
pancreatic pp cell fate commitment GO:0003329 2 0.540
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.538
morphogenesis of embryonic epithelium GO:0016331 159 0.534
neuron fate specification GO:0048665 30 0.531
respiratory system development GO:0060541 190 0.530
lymphocyte differentiation GO:0030098 242 0.529
skeletal muscle cell differentiation GO:0035914 66 0.517
axon guidance GO:0007411 141 0.513
olfactory bulb development GO:0021772 30 0.512
cation transmembrane transport GO:0098655 266 0.507
cellular amino acid metabolic process GO:0006520 103 0.503
thymus development GO:0048538 41 0.501
positive regulation of nervous system development GO:0051962 221 0.498
chemotaxis GO:0006935 247 0.493
embryonic heart tube morphogenesis GO:0003143 51 0.491
cardiac muscle cell differentiation GO:0055007 69 0.490
notch signaling pathway GO:0007219 71 0.483
telencephalon development GO:0021537 186 0.482
regulation of cellular amine metabolic process GO:0033238 20 0.478
neuron projection guidance GO:0097485 141 0.474
skeletal system development GO:0001501 356 0.468
pancreatic a cell fate commitment GO:0003326 2 0.465
cation transport GO:0006812 399 0.465
embryonic skeletal system development GO:0048706 120 0.462
urogenital system development GO:0001655 261 0.462
cranial nerve development GO:0021545 41 0.462
cell type specific apoptotic process GO:0097285 268 0.459
Mouse
axonogenesis GO:0007409 274 0.452
Mouse
stem cell maintenance GO:0019827 130 0.447
neural crest cell development GO:0014032 48 0.447
paraxial mesodermal cell fate commitment GO:0048343 2 0.446
olfactory lobe development GO:0021988 32 0.446
neural tube closure GO:0001843 90 0.441
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.440
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.434
regulation of cell cycle GO:0051726 281 0.432
leukocyte differentiation GO:0002521 342 0.431
t cell activation GO:0042110 289 0.429
regionalization GO:0003002 337 0.427
neural tube formation GO:0001841 108 0.426
somite development GO:0061053 81 0.420
neurohypophysis development GO:0021985 2 0.419
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.417
nephric duct formation GO:0072179 4 0.414
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.413
muscle cell development GO:0055001 133 0.413
apoptotic process involved in morphogenesis GO:0060561 25 0.410
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.409
positive regulation of cell motility GO:2000147 116 0.407
stem cell proliferation GO:0072089 117 0.404
nephron development GO:0072006 109 0.403
mesenchymal to epithelial transition GO:0060231 12 0.397
digestive system development GO:0055123 200 0.394
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.393
cardiac ventricle development GO:0003231 83 0.391
somitogenesis GO:0001756 69 0.390
mesoderm morphogenesis GO:0048332 64 0.389
blood vessel morphogenesis GO:0048514 285 0.389
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.389
spinal cord association neuron differentiation GO:0021527 14 0.384
muscle tissue development GO:0060537 308 0.379
epithelial cell development GO:0002064 159 0.379
regulation of stem cell differentiation GO:2000736 50 0.378
t cell differentiation GO:0030217 174 0.376
cardiac chamber morphogenesis GO:0003206 93 0.369
cytokine production GO:0001816 319 0.368
sodium ion transport GO:0006814 73 0.362
neural crest cell differentiation GO:0014033 54 0.361
lung development GO:0030324 164 0.360
negative regulation of nervous system development GO:0051961 156 0.360
heart morphogenesis GO:0003007 178 0.360
endocrine system development GO:0035270 98 0.359
embryonic placenta development GO:0001892 98 0.354
response to growth factor GO:0070848 198 0.353
epidermis development GO:0008544 187 0.352
peptidyl tyrosine modification GO:0018212 145 0.351
central nervous system neuron development GO:0021954 67 0.351
rhythmic process GO:0048511 174 0.351
embryonic organ morphogenesis GO:0048562 276 0.350
mesenchymal cell development GO:0014031 93 0.347
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.346
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.346
negative regulation of cell proliferation GO:0008285 296 0.346
ear morphogenesis GO:0042471 118 0.344
muscle tissue morphogenesis GO:0060415 53 0.343
b cell activation GO:0042113 161 0.342
regulation of neuron differentiation GO:0045664 281 0.339
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.339
neuron fate determination GO:0048664 9 0.336
morphogenesis of a branching structure GO:0001763 203 0.335
digestive tract morphogenesis GO:0048546 147 0.335
cardiac muscle tissue morphogenesis GO:0055008 44 0.335
determination of left right symmetry GO:0007368 80 0.332
gland development GO:0048732 330 0.330
angiogenesis GO:0001525 201 0.329
regulation of glial cell differentiation GO:0045685 41 0.328
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.326
regulation of organelle organization GO:0033043 289 0.326
hippocampus development GO:0021766 52 0.324
ear development GO:0043583 200 0.319
wnt signaling pathway GO:0016055 188 0.318
determination of heart left right asymmetry GO:0061371 48 0.316
paramesonephric duct development GO:0061205 3 0.316
regulation of auditory receptor cell differentiation GO:0045607 4 0.315
embryonic heart tube development GO:0035050 65 0.314
hair cycle GO:0042633 90 0.310
kidney epithelium development GO:0072073 121 0.310
regulation of secretion GO:0051046 274 0.309
sclerotome development GO:0061056 4 0.306
autonomic nervous system development GO:0048483 43 0.304
branching morphogenesis of an epithelial tube GO:0048754 159 0.303
tube formation GO:0035148 140 0.302
metanephric loop of henle development GO:0072236 4 0.302
myeloid leukocyte differentiation GO:0002573 119 0.302
pituitary gland development GO:0021983 38 0.300
regulation of gliogenesis GO:0014013 50 0.299
appendage morphogenesis GO:0035107 149 0.299
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.298
actin cytoskeleton organization GO:0030036 220 0.297
neuron migration GO:0001764 122 0.294
Mouse
forebrain neuron development GO:0021884 30 0.294
cerebral cortex development GO:0021987 86 0.294
primary neural tube formation GO:0014020 95 0.292
appendage development GO:0048736 166 0.289
tube closure GO:0060606 91 0.284
positive regulation of cellular amine metabolic process GO:0033240 5 0.282
regulation of kidney development GO:0090183 40 0.281
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.280
leukocyte homeostasis GO:0001776 79 0.279
pancreatic pp cell differentiation GO:0003312 2 0.277
forebrain neuron fate commitment GO:0021877 13 0.277
regulation of cardiac muscle tissue growth GO:0055021 26 0.277
odontogenesis of dentin containing tooth GO:0042475 66 0.276
blastocyst formation GO:0001825 33 0.275
heart formation GO:0060914 16 0.273
odontogenesis GO:0042476 78 0.273
cell differentiation in hindbrain GO:0021533 24 0.269
limb development GO:0060173 166 0.268
negative regulation of cell development GO:0010721 169 0.267
auditory receptor cell fate specification GO:0042667 1 0.265
immune effector process GO:0002252 321 0.264
gabaergic neuron differentiation GO:0097154 11 0.264
neural crest cell migration GO:0001755 32 0.262
metanephros development GO:0001656 79 0.261
metencephalon development GO:0022037 89 0.260
negative regulation of protein modification process GO:0031400 163 0.259
cardiac muscle tissue development GO:0048738 130 0.257
alpha beta t cell activation GO:0046631 91 0.254
striated muscle tissue development GO:0014706 293 0.253
cellular response to growth factor stimulus GO:0071363 197 0.252
glandular epithelial cell differentiation GO:0002067 38 0.251
brain morphogenesis GO:0048854 32 0.248
transdifferentiation GO:0060290 1 0.247
cardiac cell development GO:0055006 41 0.245
glial cell fate commitment GO:0021781 14 0.245
regulation of lymphocyte apoptotic process GO:0070228 41 0.243
cation homeostasis GO:0055080 212 0.243
spemann organizer formation GO:0060061 2 0.242
inner ear morphogenesis GO:0042472 101 0.242
endoderm development GO:0007492 45 0.240
formation of primary germ layer GO:0001704 77 0.239
dendrite development GO:0016358 115 0.239
embryonic appendage morphogenesis GO:0035113 126 0.238
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.238
regulation of muscle tissue development GO:1901861 97 0.237
ventral spinal cord interneuron differentiation GO:0021514 16 0.237
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.236
epithelial cell fate commitment GO:0072148 13 0.234
regulation of organ formation GO:0003156 34 0.234
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.232
connective tissue development GO:0061448 179 0.231
positive regulation of cell migration GO:0030335 109 0.228
placenta development GO:0001890 140 0.226
positive regulation of epithelial cell proliferation GO:0050679 68 0.225
oxygen homeostasis GO:0032364 2 0.221
outflow tract morphogenesis GO:0003151 53 0.221
regulation of lymphocyte activation GO:0051249 240 0.221
erythrocyte differentiation GO:0030218 88 0.220
regulation of organ growth GO:0046620 61 0.220
amine metabolic process GO:0009308 45 0.220
mesenchyme morphogenesis GO:0072132 32 0.219
regulation of fat cell differentiation GO:0045598 81 0.219
ventral spinal cord development GO:0021517 48 0.218
positive regulation of keratinocyte proliferation GO:0010838 4 0.216
regulation of retina development in camera type eye GO:1902866 3 0.216
myotube differentiation GO:0014902 105 0.216
regulation of oligodendrocyte differentiation GO:0048713 23 0.216
mesoderm formation GO:0001707 62 0.214
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 5 0.213
dorsal spinal cord development GO:0021516 20 0.213
segmentation GO:0035282 93 0.210
apoptotic signaling pathway GO:0097190 306 0.208
cell differentiation involved in kidney development GO:0061005 33 0.208
muscle cell proliferation GO:0033002 52 0.206
regulation of cardiac muscle cell proliferation GO:0060043 23 0.206
developmental maturation GO:0021700 193 0.205
regulation of cell division GO:0051302 76 0.203
skeletal muscle organ development GO:0060538 163 0.202
synaptic transmission GO:0007268 329 0.202
regulation of ion transport GO:0043269 215 0.201
positive regulation of kidney development GO:0090184 28 0.201
nucleoside phosphate metabolic process GO:0006753 338 0.199
forelimb morphogenesis GO:0035136 40 0.199
regulation of embryonic development GO:0045995 71 0.198
oligodendrocyte differentiation GO:0048709 53 0.197
neural precursor cell proliferation GO:0061351 121 0.197
neuroblast differentiation GO:0014016 2 0.197
positive regulation of glial cell differentiation GO:0045687 21 0.197
hair follicle development GO:0001942 85 0.196
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.195
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.195
ventricular cardiac muscle tissue development GO:0003229 38 0.195
regulation of bmp signaling pathway GO:0030510 60 0.194
cardiac septum development GO:0003279 59 0.194
cardiac ventricle morphogenesis GO:0003208 50 0.194
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.193
positive regulation of stem cell proliferation GO:2000648 59 0.193
nerve development GO:0021675 67 0.190
regulation of lymphocyte proliferation GO:0050670 117 0.188
mitochondrion distribution GO:0048311 4 0.188
negative regulation of intracellular signal transduction GO:1902532 167 0.187
ureteric bud development GO:0001657 94 0.186
ectoderm formation GO:0001705 3 0.185
positive regulation of stem cell differentiation GO:2000738 23 0.183
hypophysis morphogenesis GO:0048850 3 0.183
trophectodermal cell differentiation GO:0001829 21 0.182
neurotransmitter transport GO:0006836 76 0.182
artery development GO:0060840 53 0.182
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.181
metanephric nephron morphogenesis GO:0072273 19 0.180
regulation of chromatin modification GO:1903308 57 0.180
developmental induction GO:0031128 34 0.180
protein secretion GO:0009306 111 0.179
midbrain hindbrain boundary maturation GO:0021732 1 0.178
ossification GO:0001503 216 0.177
regulation of neural retina development GO:0061074 3 0.177
regulation of cell projection organization GO:0031344 206 0.176
Mouse
mitral valve development GO:0003174 4 0.176
positive regulation of programmed cell death GO:0043068 218 0.175
cervix development GO:0060067 2 0.174
regulation of wnt signaling pathway GO:0030111 123 0.174
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.174
smoothened signaling pathway GO:0007224 105 0.174
striated muscle cell development GO:0055002 125 0.173
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.173
regulation of heart growth GO:0060420 31 0.171
regulation of circadian rhythm GO:0042752 58 0.171
hematopoietic progenitor cell differentiation GO:0002244 143 0.170
inorganic cation transmembrane transport GO:0098662 207 0.170
positive regulation of neuron differentiation GO:0045666 141 0.170
cell cell signaling involved in cell fate commitment GO:0045168 35 0.169
positive regulation of neural precursor cell proliferation GO:2000179 42 0.169
purine containing compound metabolic process GO:0072521 311 0.168
apoptotic process involved in development GO:1902742 28 0.167
regulation of nucleotide metabolic process GO:0006140 169 0.167
positive regulation of secretion by cell GO:1903532 114 0.166
positive regulation of apoptotic process GO:0043065 217 0.165
nephron tubule morphogenesis GO:0072078 68 0.164
regulation of apoptotic signaling pathway GO:2001233 197 0.163
gas homeostasis GO:0033483 3 0.163
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.163
auditory receptor cell differentiation GO:0042491 37 0.163
axis elongation involved in somitogenesis GO:0090245 4 0.162
somatotropin secreting cell development GO:0060133 2 0.162
myeloid cell differentiation GO:0030099 233 0.162
embryonic heart tube formation GO:0003144 1 0.162
negative regulation of molecular function GO:0044092 258 0.161
developmental growth involved in morphogenesis GO:0060560 138 0.160
Mouse
negative regulation of prostatic bud formation GO:0060686 4 0.160
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.159
regulation of neuron projection development GO:0010975 169 0.159
Mouse
nephron tubule development GO:0072080 84 0.158
response to transforming growth factor beta GO:0071559 88 0.158
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.157
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.156
b cell proliferation GO:0042100 53 0.156
transmembrane transport GO:0055085 412 0.156
cell maturation GO:0048469 127 0.156
neuron projection extension GO:1990138 64 0.155
Mouse
chromatin organization GO:0006325 206 0.155
establishment of organ orientation GO:0048561 1 0.154
striated muscle cell proliferation GO:0014855 39 0.153
carbohydrate derivative biosynthetic process GO:1901137 183 0.152
camera type eye development GO:0043010 266 0.152
positive regulation of cell death GO:0010942 224 0.151
myoblast differentiation GO:0045445 52 0.151
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.149
ureteric bud morphogenesis GO:0060675 62 0.149
negative regulation of synapse assembly GO:0051964 3 0.148
mesonephric epithelium development GO:0072163 94 0.146
hair cell differentiation GO:0035315 40 0.146
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.146
regulation of asymmetric cell division GO:0009786 4 0.145
glial cell differentiation GO:0010001 131 0.145
positive regulation of organelle organization GO:0010638 128 0.144
positive regulation of protein phosphorylation GO:0001934 242 0.143
spinal cord dorsal ventral patterning GO:0021513 23 0.143
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.143
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.143
dorsal ventral neural tube patterning GO:0021904 28 0.143
cardiac epithelial to mesenchymal transition GO:0060317 18 0.143
foregut regionalization GO:0060423 3 0.143
organic cyclic compound catabolic process GO:1901361 295 0.142
olfactory bulb interneuron differentiation GO:0021889 12 0.142
hemangioblast cell differentiation GO:0060217 1 0.141
lung morphogenesis GO:0060425 50 0.141
cardiac right atrium morphogenesis GO:0003213 3 0.140
forebrain cell migration GO:0021885 58 0.140
peptidyl tyrosine phosphorylation GO:0018108 143 0.140
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.140
embryonic limb morphogenesis GO:0030326 126 0.139
motor neuron axon guidance GO:0008045 26 0.139
peptidyl amino acid modification GO:0018193 336 0.139
actomyosin structure organization GO:0031032 56 0.139
cardiac chamber development GO:0003205 108 0.138
regulation of membrane potential GO:0042391 192 0.137
loop of henle development GO:0072070 10 0.137
catecholamine metabolic process GO:0006584 30 0.137
lymphocyte homeostasis GO:0002260 64 0.136
regulation of binding GO:0051098 111 0.136
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.136
central nervous system vasculogenesis GO:0022009 3 0.135
regulation of cardiac muscle tissue development GO:0055024 31 0.134
limb morphogenesis GO:0035108 149 0.134
heterocycle catabolic process GO:0046700 280 0.133
head morphogenesis GO:0060323 34 0.133
cardiac muscle cell proliferation GO:0060038 31 0.133
nephron epithelium development GO:0072009 92 0.133
carbohydrate homeostasis GO:0033500 128 0.133
sodium ion transmembrane transport GO:0035725 49 0.133
cardiac right ventricle formation GO:0003219 3 0.132
lung induction GO:0060492 3 0.132
action potential GO:0001508 78 0.131
chondrocyte differentiation GO:0002062 72 0.131
mesonephric tubule morphogenesis GO:0072171 63 0.131
embryonic skeletal system morphogenesis GO:0048704 91 0.130
regulation of mapk cascade GO:0043408 248 0.130
epithelial cell morphogenesis GO:0003382 41 0.130
regulation of kinase activity GO:0043549 249 0.129
germ cell development GO:0007281 185 0.129
paraxial mesoderm development GO:0048339 18 0.129
negative regulation of phosphate metabolic process GO:0045936 184 0.129
tissue remodeling GO:0048771 102 0.128
retina development in camera type eye GO:0060041 119 0.128
mitotic cell cycle process GO:1903047 159 0.128
regulation of anagen GO:0051884 1 0.127
kidney rudiment formation GO:0072003 3 0.127
establishment or maintenance of cell polarity GO:0007163 86 0.126
positive regulation of synaptic plasticity GO:0031915 4 0.126
hindbrain formation GO:0021576 1 0.126
fat cell differentiation GO:0045444 160 0.125
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.125
negative regulation of neuron projection development GO:0010977 50 0.125
telencephalon cell migration GO:0022029 55 0.124
cerebral cortex cell migration GO:0021795 44 0.124
inner ear receptor cell differentiation GO:0060113 61 0.124
positive regulation of secretion GO:0051047 130 0.124
metanephric nephron epithelium development GO:0072243 19 0.124
metanephric nephron development GO:0072210 34 0.124
digestive tract development GO:0048565 190 0.124
neuroepithelial cell differentiation GO:0060563 37 0.123
embryonic eye morphogenesis GO:0048048 29 0.123
regulation of hormone levels GO:0010817 211 0.123
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.123
renal inner medulla development GO:0072053 3 0.122
glycoprotein metabolic process GO:0009100 116 0.121
negative regulation of cell cycle GO:0045786 123 0.121
protein modification by small protein conjugation or removal GO:0070647 207 0.120
post anal tail morphogenesis GO:0036342 23 0.119
morphogenesis of a branching epithelium GO:0061138 193 0.119
b cell differentiation GO:0030183 78 0.119
negative regulation of neuron differentiation GO:0045665 101 0.118
inorganic ion transmembrane transport GO:0098660 234 0.117
purine ribonucleotide metabolic process GO:0009150 290 0.117
t cell differentiation in thymus GO:0033077 77 0.116
tongue development GO:0043586 18 0.116
palate development GO:0060021 76 0.116
spinal cord motor neuron differentiation GO:0021522 35 0.116
tendon formation GO:0035992 4 0.115
regulation of cellular catabolic process GO:0031329 242 0.115
ameboidal type cell migration GO:0001667 128 0.115
cellular potassium ion transport GO:0071804 43 0.115
protein ubiquitination GO:0016567 171 0.115
regulation of transmembrane transport GO:0034762 128 0.115
somatic stem cell maintenance GO:0035019 47 0.114
negative regulation of kinase activity GO:0033673 81 0.114
neuron apoptotic process GO:0051402 142 0.113
Mouse
hindbrain morphogenesis GO:0021575 46 0.113
regulation of lipid metabolic process GO:0019216 118 0.113
immunoglobulin production GO:0002377 73 0.113
renal system development GO:0072001 225 0.113
inner medullary collecting duct development GO:0072061 2 0.112
epithelial to mesenchymal transition GO:0001837 47 0.111
renal vesicle induction GO:0072034 3 0.111
cell fate commitment involved in pattern specification GO:0060581 14 0.111
leukocyte apoptotic process GO:0071887 71 0.110
cellular chemical homeostasis GO:0055082 215 0.110
regulation of cell migration GO:0030334 219 0.110
regulation of canonical wnt signaling pathway GO:0060828 82 0.110
mesenchymal cell proliferation GO:0010463 44 0.109
dopaminergic neuron differentiation GO:0071542 14 0.109
neural fold elevation formation GO:0021502 1 0.108
mesonephric duct formation GO:0072181 2 0.108
mapk cascade GO:0000165 281 0.108
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.107
regulation of cytokine production GO:0001817 266 0.107
male sex differentiation GO:0046661 109 0.106
regulation of map kinase activity GO:0043405 120 0.106
mammary gland morphogenesis GO:0060443 54 0.106
regulation of tube size GO:0035150 57 0.106
polarity specification of proximal distal axis GO:0010085 2 0.106
regulation of homeostatic process GO:0032844 182 0.106
nephron morphogenesis GO:0072028 69 0.105
mitochondrion organization GO:0007005 134 0.105
positive regulation of mapk cascade GO:0043410 170 0.104
positive regulation of lymphocyte activation GO:0051251 140 0.104
regulation of purine nucleotide metabolic process GO:1900542 169 0.104
positive regulation of neuroblast proliferation GO:0002052 19 0.104
mesonephros development GO:0001823 97 0.104
metanephric dct cell differentiation GO:0072240 3 0.104
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.104
purine nucleotide metabolic process GO:0006163 302 0.103
purine nucleoside catabolic process GO:0006152 205 0.102
cellular ion homeostasis GO:0006873 165 0.102
regulation of histone modification GO:0031056 56 0.102
nucleobase containing small molecule metabolic process GO:0055086 352 0.101
mesonephric tubule formation GO:0072172 11 0.101
forebrain regionalization GO:0021871 25 0.101
oviduct development GO:0060066 3 0.100
cell adhesion GO:0007155 329 0.100
regulation of cellular response to growth factor stimulus GO:0090287 82 0.100
gliogenesis GO:0042063 141 0.100
gastrulation with mouth forming second GO:0001702 29 0.099
renal tubule development GO:0061326 87 0.099
myeloid cell homeostasis GO:0002262 114 0.098
cardiac muscle tissue growth GO:0055017 37 0.098
muscle system process GO:0003012 141 0.098
regulation of leukocyte proliferation GO:0070663 121 0.098
regulation of leukocyte apoptotic process GO:2000106 56 0.097
ribonucleoside metabolic process GO:0009119 245 0.097
cellular homeostasis GO:0019725 240 0.096
cerebral cortex neuron differentiation GO:0021895 19 0.096
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.096
pancreas development GO:0031016 57 0.096
regulation of cell cycle process GO:0010564 160 0.096
regulation of carbohydrate metabolic process GO:0006109 75 0.096
heart growth GO:0060419 45 0.096
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.096
development of primary male sexual characteristics GO:0046546 88 0.095
cardiac cell fate determination GO:0060913 2 0.095
positive regulation of heart growth GO:0060421 18 0.095
metanephric epithelium development GO:0072207 21 0.095

Nkx1-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org