Mus musculus

147 known processes

Nkx2-3

NK2 transcription factor related, locus 3 (Drosophila)

(Aliases: Nkx-2.3,Nkx2.3,tinman)

Nkx2-3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
striated muscle tissue development GO:0014706 293 0.862
Mouse
organ growth GO:0035265 117 0.859
Mouse
oligodendrocyte differentiation GO:0048709 53 0.832
Mouse
muscle tissue development GO:0060537 308 0.826
Mouse
spleen development GO:0048536 39 0.825
regionalization GO:0003002 337 0.809
Mouse
heart morphogenesis GO:0003007 178 0.800
Mouse
muscle cell development GO:0055001 133 0.791
Mouse
digestive system development GO:0055123 200 0.766
cardiocyte differentiation GO:0035051 87 0.748
Mouse
digestive tract development GO:0048565 190 0.740
regulation of gliogenesis GO:0014013 50 0.723
Mouse
gliogenesis GO:0042063 141 0.716
Mouse
positive regulation of cell development GO:0010720 237 0.683
Mouse
calcium ion transport GO:0006816 159 0.682
Mouse
negative regulation of cell fate specification GO:0009996 4 0.665
epithelial tube morphogenesis GO:0060562 303 0.661
Mouse
glial cell differentiation GO:0010001 131 0.651
Mouse
antimicrobial peptide production GO:0002775 2 0.649
regulation of glial cell differentiation GO:0045685 41 0.646
Mouse
telencephalon development GO:0021537 186 0.643
Mouse
positive regulation of cytokine production GO:0001819 174 0.639
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.629
Mouse
kidney development GO:0001822 213 0.629
organic hydroxy compound metabolic process GO:1901615 203 0.625
positive regulation of neuron differentiation GO:0045666 141 0.592
Mouse
neuromuscular process GO:0050905 99 0.590
axonogenesis GO:0007409 274 0.587
Mouse
cerebral cortex development GO:0021987 86 0.585
Mouse
action potential GO:0001508 78 0.584
neuroepithelial cell differentiation GO:0060563 37 0.565
regulation of apoptotic signaling pathway GO:2001233 197 0.562
synaptic transmission GO:0007268 329 0.561
developmental induction GO:0031128 34 0.560
Mouse
skeletal system development GO:0001501 356 0.558
Mouse
astrocyte fate commitment GO:0060018 4 0.555
cardiac muscle tissue development GO:0048738 130 0.554
Mouse
locomotory behavior GO:0007626 195 0.549
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.547
neuronal action potential GO:0019228 54 0.538
positive regulation of nervous system development GO:0051962 221 0.537
Mouse
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.536
cardiac chamber morphogenesis GO:0003206 93 0.521
Mouse
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.516
Mouse
forebrain cell migration GO:0021885 58 0.511
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.494
regulation of secretion GO:0051046 274 0.492
determination of left right symmetry GO:0007368 80 0.485
Mouse
multicellular organismal signaling GO:0035637 91 0.481
mapk cascade GO:0000165 281 0.466
telencephalon cell migration GO:0022029 55 0.464
Mouse
transmission of nerve impulse GO:0019226 76 0.461
skeletal system morphogenesis GO:0048705 203 0.455
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.450
Mouse
regulation of hormone secretion GO:0046883 88 0.446
nitrogen compound transport GO:0071705 271 0.439
muscle cell differentiation GO:0042692 261 0.435
Mouse
carboxylic acid transport GO:0046942 100 0.430
response to organonitrogen compound GO:0010243 246 0.425
camera type eye development GO:0043010 266 0.423
extrinsic apoptotic signaling pathway GO:0097191 126 0.422
stem cell development GO:0048864 219 0.420
mesoderm development GO:0007498 100 0.420
lung cell differentiation GO:0060479 30 0.418
Mouse
axon guidance GO:0007411 141 0.410
Mouse
antimicrobial peptide biosynthetic process GO:0002777 2 0.410
positive regulation of transcription via serum response element binding GO:0010735 1 0.408
Mouse
lung development GO:0030324 164 0.393
Mouse
acid secretion GO:0046717 33 0.389
regulation of antimicrobial humoral response GO:0002759 3 0.386
negative regulation of gastrulation GO:2000542 3 0.384
limb development GO:0060173 166 0.384
respiratory tube development GO:0030323 167 0.383
Mouse
positive regulation of gliogenesis GO:0014015 27 0.382
Mouse
renal system development GO:0072001 225 0.382
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.380
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.379
extracellular matrix organization GO:0030198 147 0.376
developmental programmed cell death GO:0010623 41 0.374
Mouse
establishment of protein localization to organelle GO:0072594 118 0.372
cerebral cortex cell migration GO:0021795 44 0.369
Mouse
renal vesicle induction GO:0072034 3 0.366
transmembrane transport GO:0055085 412 0.365
Mouse
lymph node development GO:0048535 18 0.365
regulation of protein kinase activity GO:0045859 232 0.358
intestinal epithelial cell differentiation GO:0060575 14 0.356
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.355
cation transport GO:0006812 399 0.355
Mouse
myelination GO:0042552 74 0.354
pancreatic a cell fate commitment GO:0003326 2 0.353
Mouse
pancreatic pp cell differentiation GO:0003312 2 0.351
Mouse
regulation of membrane potential GO:0042391 192 0.350
cardiac ventricle development GO:0003231 83 0.350
Mouse
purkinje myocyte differentiation GO:0003168 1 0.349
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.344
regulation of organ growth GO:0046620 61 0.341
Mouse
intracellular protein transport GO:0006886 204 0.334
amide transport GO:0042886 138 0.333
regulation of b cell proliferation GO:0030888 39 0.328
circadian rhythm GO:0007623 114 0.326
Mouse
appendage morphogenesis GO:0035107 149 0.324
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.323
Mouse
ensheathment of neurons GO:0007272 76 0.323
forebrain development GO:0030900 302 0.322
Mouse
response to organic cyclic compound GO:0014070 198 0.322
response to acid chemical GO:0001101 111 0.321
cell fate commitment GO:0045165 210 0.319
Mouse
digestive tract morphogenesis GO:0048546 147 0.317
leukocyte differentiation GO:0002521 342 0.317
positive regulation of interferon gamma production GO:0032729 39 0.316
sensory organ morphogenesis GO:0090596 242 0.316
Mouse
muscle system process GO:0003012 141 0.316
Mouse
multicellular organismal response to stress GO:0033555 62 0.315
stem cell differentiation GO:0048863 268 0.313
Mouse
appendage development GO:0048736 166 0.312
male sex determination GO:0030238 14 0.308
regulation of ion transmembrane transport GO:0034765 119 0.302
Mouse
embryonic organ morphogenesis GO:0048562 276 0.302
Mouse
skeletal muscle organ development GO:0060538 163 0.302
regulation of organ morphogenesis GO:2000027 144 0.296
cardiac chamber development GO:0003205 108 0.295
Mouse
atrioventricular node cell differentiation GO:0060922 2 0.295
Mouse
cardiac muscle cell differentiation GO:0055007 69 0.291
Mouse
angiogenesis GO:0001525 201 0.290
regulation of intracellular protein transport GO:0033157 82 0.289
pancreatic pp cell fate commitment GO:0003329 2 0.288
Mouse
embryonic placenta development GO:0001892 98 0.286
embryonic epithelial tube formation GO:0001838 130 0.286
hair follicle development GO:0001942 85 0.285
central nervous system neuron differentiation GO:0021953 162 0.284
Mouse
embryonic limb morphogenesis GO:0030326 126 0.282
lung epithelium development GO:0060428 37 0.281
Mouse
apoptotic process involved in morphogenesis GO:0060561 25 0.278
Mouse
metal ion homeostasis GO:0055065 189 0.277
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.276
Mouse
spinal cord motor neuron differentiation GO:0021522 35 0.275
Mouse
septum primum development GO:0003284 4 0.272
single organism nuclear import GO:1902593 95 0.272
humoral immune response GO:0006959 57 0.272
sensory perception GO:0007600 245 0.272
cellular component assembly involved in morphogenesis GO:0010927 139 0.270
Mouse
cellular lipid metabolic process GO:0044255 323 0.269
regulation of morphogenesis of a branching structure GO:0060688 53 0.268
epithelial cell proliferation GO:0050673 174 0.267
Mouse
positive regulation of cell activation GO:0050867 158 0.266
protein import GO:0017038 101 0.263
cell fate determination involved in pattern specification GO:0060582 1 0.263
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.262
Mouse
negative regulation of immune system process GO:0002683 209 0.262
cation homeostasis GO:0055080 212 0.261
t cell differentiation in thymus GO:0033077 77 0.259
lung morphogenesis GO:0060425 50 0.259
regulation of mapk cascade GO:0043408 248 0.258
positive regulation of leukocyte proliferation GO:0070665 73 0.257
organonitrogen compound biosynthetic process GO:1901566 192 0.256
anion transport GO:0006820 177 0.256
nephron epithelium morphogenesis GO:0072088 68 0.255
ventral spinal cord interneuron fate commitment GO:0060579 14 0.254
Mouse
blood vessel morphogenesis GO:0048514 285 0.254
Mouse
ventral spinal cord development GO:0021517 48 0.254
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.251
limb morphogenesis GO:0035108 149 0.250
morphogenesis of a branching structure GO:0001763 203 0.248
ureteric bud morphogenesis GO:0060675 62 0.248
mesodermal cell differentiation GO:0048333 22 0.248
cardiac septum development GO:0003279 59 0.247
gland development GO:0048732 330 0.245
cardiac pacemaker cell fate commitment GO:0060927 1 0.245
Mouse
urogenital system development GO:0001655 261 0.243
respiratory system development GO:0060541 190 0.243
Mouse
endocrine system development GO:0035270 98 0.243
Mouse
protein localization to nucleus GO:0034504 121 0.239
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.236
cytokine production GO:0001816 319 0.236
rhythmic process GO:0048511 174 0.236
Mouse
salivary gland development GO:0007431 37 0.235
organic anion transport GO:0015711 137 0.235
liver development GO:0001889 66 0.235
regulation of secretion by cell GO:1903530 249 0.235
molting cycle GO:0042303 90 0.235
intestinal epithelial structure maintenance GO:0060729 4 0.234
positive regulation of mapk cascade GO:0043410 170 0.234
glycoprotein metabolic process GO:0009100 116 0.233
positive regulation of interleukin 12 production GO:0032735 21 0.230
hormone secretion GO:0046879 128 0.230
glial cell fate commitment GO:0021781 14 0.230
Mouse
divalent metal ion transport GO:0070838 172 0.229
Mouse
heart growth GO:0060419 45 0.227
Mouse
cardiac septum morphogenesis GO:0060411 46 0.226
cellular metal ion homeostasis GO:0006875 151 0.224
neural crest cell development GO:0014032 48 0.223
divalent inorganic cation homeostasis GO:0072507 138 0.223
apoptotic signaling pathway GO:0097190 306 0.222
epidermis development GO:0008544 187 0.221
paraxial mesodermal cell differentiation GO:0048342 2 0.221
regulation of gastrulation GO:0010470 16 0.221
neuron projection extension GO:1990138 64 0.220
interleukin 1 beta production GO:0032611 30 0.219
renal tubule development GO:0061326 87 0.217
cellular ketone metabolic process GO:0042180 84 0.214
regulation of neuron differentiation GO:0045664 281 0.213
Mouse
germ cell development GO:0007281 185 0.212
cell type specific apoptotic process GO:0097285 268 0.211
Mouse
response to growth factor GO:0070848 198 0.211
regulation of protein targeting GO:1903533 61 0.211
positive regulation of apoptotic process GO:0043065 217 0.210
regulation of ion transport GO:0043269 215 0.210
Mouse
regulation of protein transport GO:0051223 163 0.210
cerebral cortex neuron differentiation GO:0021895 19 0.209
Mouse
regulation of cytokine production GO:0001817 266 0.207
positive regulation of programmed cell death GO:0043068 218 0.206
positive regulation of angiogenesis GO:0045766 46 0.206
sensory perception of sound GO:0007605 97 0.205
nuclear transport GO:0051169 139 0.204
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.204
Mouse
mesenchyme development GO:0060485 152 0.204
Mouse
regulation of cell motility GO:2000145 236 0.204
protein import into nucleus GO:0006606 95 0.204
regulation of cardioblast differentiation GO:0051890 3 0.204
Mouse
cellular amino acid metabolic process GO:0006520 103 0.204
b cell differentiation GO:0030183 78 0.203
ventricular cardiac myofibril assembly GO:0055005 3 0.203
Mouse
fat cell differentiation GO:0045444 160 0.202
negative regulation of defense response GO:0031348 77 0.202
axon ensheathment GO:0008366 76 0.202
positive regulation of apoptotic signaling pathway GO:2001235 95 0.200
epithelial cell development GO:0002064 159 0.200
Mouse
hippocampus development GO:0021766 52 0.200
Mouse
regulation of oligodendrocyte differentiation GO:0048713 23 0.198
Mouse
renal tubule morphogenesis GO:0061333 72 0.198
stem cell fate specification GO:0048866 3 0.196
regulation of map kinase activity GO:0043405 120 0.196
syncytium formation by plasma membrane fusion GO:0000768 42 0.194
embryonic appendage morphogenesis GO:0035113 126 0.193
positive regulation of lymphocyte proliferation GO:0050671 70 0.193
regulation of antimicrobial peptide production GO:0002784 1 0.193
determination of heart left right asymmetry GO:0061371 48 0.193
Mouse
hexose metabolic process GO:0019318 98 0.192
regulation of cellular ketone metabolic process GO:0010565 66 0.190
ventricular septum development GO:0003281 42 0.190
ear development GO:0043583 200 0.190
Mouse
immune response activating signal transduction GO:0002757 116 0.190
regulation of lymphocyte proliferation GO:0050670 117 0.189
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.189
ureteric bud development GO:0001657 94 0.188
mesonephros development GO:0001823 97 0.188
developmental growth involved in morphogenesis GO:0060560 138 0.187
mesonephric tubule development GO:0072164 94 0.186
regulation of cardiac cell fate specification GO:2000043 1 0.186
cardiac cell fate specification GO:0060912 2 0.186
gastrulation GO:0007369 116 0.186
negative regulation of exocytosis GO:0045920 12 0.184
compound eye development GO:0048749 1 0.183
metanephros development GO:0001656 79 0.183
protein kinase b signaling GO:0043491 74 0.181
multicellular organismal homeostasis GO:0048871 164 0.181
male sex differentiation GO:0046661 109 0.180
Mouse
pancreas development GO:0031016 57 0.180
Mouse
regulation of protein import into nucleus GO:0042306 52 0.180
peptide transport GO:0015833 133 0.179
ameboidal type cell migration GO:0001667 128 0.179
cell fate specification GO:0001708 72 0.178
Mouse
nephron tubule formation GO:0072079 20 0.177
protein targeting GO:0006605 143 0.176
cell differentiation in spinal cord GO:0021515 53 0.176
Mouse
cytoplasmic transport GO:0016482 234 0.175
nephron tubule morphogenesis GO:0072078 68 0.175
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.174
regulation of neural precursor cell proliferation GO:2000177 70 0.173
embryonic digestive tract development GO:0048566 27 0.172
monocarboxylic acid transport GO:0015718 44 0.171
embryonic skeletal system morphogenesis GO:0048704 91 0.171
skin development GO:0043588 220 0.171
temperature homeostasis GO:0001659 26 0.170
immune effector process GO:0002252 321 0.170
negative regulation of mesodermal cell fate specification GO:0042662 3 0.170
negative regulation of secretion GO:0051048 61 0.169
cell cell signaling involved in cell fate commitment GO:0045168 35 0.168
Mouse
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.167
neuron migration GO:0001764 122 0.167
Mouse
endodermal cell fate specification GO:0001714 4 0.167
negative regulation of cell development GO:0010721 169 0.166
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.165
regulation of neuron apoptotic process GO:0043523 122 0.165
ion transmembrane transport GO:0034220 361 0.164
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.164
posttranscriptional regulation of gene expression GO:0010608 155 0.163
regulation of interferon gamma production GO:0032649 57 0.163
neuromuscular process controlling balance GO:0050885 59 0.163
myeloid cell differentiation GO:0030099 233 0.162
establishment or maintenance of cell polarity GO:0007163 86 0.161
regulation of protein serine threonine kinase activity GO:0071900 157 0.161
endomembrane system organization GO:0010256 147 0.160
gabaergic neuron differentiation GO:0097154 11 0.159
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.159
Mouse
regulation of chondrocyte differentiation GO:0032330 33 0.159
Mouse
regulation of vasculature development GO:1901342 88 0.158
menarche GO:0042696 1 0.157
Mouse
ventricular septum morphogenesis GO:0060412 27 0.157
sensory perception of pain GO:0019233 47 0.157
regulation of defense response GO:0031347 233 0.155
regulation of peptide secretion GO:0002791 77 0.155
limbic system development GO:0021761 72 0.154
Mouse
positive regulation of translational initiation GO:0045948 4 0.153
glial cell development GO:0021782 54 0.152
Mouse
tube formation GO:0035148 140 0.152
placenta development GO:0001890 140 0.152
pituitary gland development GO:0021983 38 0.152
Mouse
hair cycle GO:0042633 90 0.151
lipid biosynthetic process GO:0008610 179 0.150
columnar cuboidal epithelial cell development GO:0002066 29 0.149
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.149
myeloid leukocyte differentiation GO:0002573 119 0.149
astrocyte differentiation GO:0048708 43 0.149
Mouse
globus pallidus development GO:0021759 2 0.148
Mouse
cardiac cell fate determination GO:0060913 2 0.148
peripheral nervous system development GO:0007422 53 0.146
carbohydrate derivative biosynthetic process GO:1901137 183 0.146
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.146
positive regulation of stem cell proliferation GO:2000648 59 0.146
regulation of peptide transport GO:0090087 91 0.145
cellular homeostasis GO:0019725 240 0.144
positive regulation of map kinase activity GO:0043406 84 0.144
regulation of cell activation GO:0050865 289 0.144
membrane depolarization GO:0051899 64 0.143
organic acid transport GO:0015849 101 0.143
regulation of branching involved in salivary gland morphogenesis GO:0060693 11 0.142
regulation of response to wounding GO:1903034 189 0.142
cellular amine metabolic process GO:0044106 44 0.142
organ induction GO:0001759 21 0.140
sa node cell action potential GO:0086015 4 0.139
cellular response to external stimulus GO:0071496 88 0.136
striated muscle cell development GO:0055002 125 0.136
Mouse
positive regulation of glial cell differentiation GO:0045687 21 0.136
Mouse
embryonic digestive tract morphogenesis GO:0048557 17 0.136
regulation of cell cycle GO:0051726 281 0.135
epithelial tube formation GO:0072175 130 0.134
regulation of peptide hormone secretion GO:0090276 75 0.133
ras protein signal transduction GO:0007265 77 0.133
renal vesicle development GO:0072087 17 0.133
central nervous system vasculogenesis GO:0022009 3 0.133
peptide hormone secretion GO:0030072 109 0.133
dendrite development GO:0016358 115 0.132
development of primary male sexual characteristics GO:0046546 88 0.131
Mouse
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.131
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.130
cytokine biosynthetic process GO:0042089 68 0.130
regulation of intracellular transport GO:0032386 159 0.130
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.130
closure of optic fissure GO:0061386 2 0.130
regulation of anatomical structure size GO:0090066 178 0.129
embryonic heart tube development GO:0035050 65 0.129
Mouse
positive regulation of b cell proliferation GO:0030890 24 0.129
auditory receptor cell fate determination GO:0042668 3 0.129
regulation of neuron projection development GO:0010975 169 0.129
oviduct development GO:0060066 3 0.127
neural tube development GO:0021915 160 0.127
nucleocytoplasmic transport GO:0006913 139 0.126
artery development GO:0060840 53 0.124
skeletal muscle fiber development GO:0048741 58 0.124
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.124
stem cell proliferation GO:0072089 117 0.123
response to radiation GO:0009314 165 0.123
branching involved in ureteric bud morphogenesis GO:0001658 56 0.123
mesoderm formation GO:0001707 62 0.122
formation of primary germ layer GO:0001704 77 0.122
mesodermal cell fate commitment GO:0001710 17 0.122
branching morphogenesis of an epithelial tube GO:0048754 159 0.121
pigmentation GO:0043473 71 0.121
mesonephric epithelium development GO:0072163 94 0.120
mesonephric duct morphogenesis GO:0072180 4 0.120
nephron tubule development GO:0072080 84 0.119
amine metabolic process GO:0009308 45 0.119
regulation of cellular response to growth factor stimulus GO:0090287 82 0.119
neural precursor cell proliferation GO:0061351 121 0.118
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.118
divalent inorganic cation transport GO:0072511 178 0.118
Mouse
regulation of white fat cell proliferation GO:0070350 2 0.118
hepaticobiliary system development GO:0061008 67 0.118
peptide biosynthetic process GO:0043043 11 0.117
positive regulation of mitotic cell cycle GO:0045931 41 0.116
regulation of transmembrane transport GO:0034762 128 0.116
Mouse
inner medullary collecting duct development GO:0072061 2 0.116
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.116
regulation of mesodermal cell fate specification GO:0042661 5 0.115
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.115
Mouse
nuclear import GO:0051170 95 0.115
regulation of cell migration GO:0030334 219 0.114
cellular chemical homeostasis GO:0055082 215 0.114
regulation of establishment of protein localization GO:0070201 181 0.114
cell growth GO:0016049 130 0.114
protein localization to organelle GO:0033365 185 0.114
somatic stem cell maintenance GO:0035019 47 0.113
regulation of interleukin 6 production GO:0032675 55 0.113
neural tube patterning GO:0021532 43 0.113
corticotropin hormone secreting cell differentiation GO:0060128 3 0.113
regulation of bone mineralization GO:0030500 31 0.113
negative regulation of cartilage development GO:0061037 17 0.113
Mouse
regulation of protein localization GO:0032880 231 0.112
smoothened signaling pathway GO:0007224 105 0.112
Mouse
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.112
negative regulation of glial cell proliferation GO:0060253 4 0.112
retina development in camera type eye GO:0060041 119 0.111
stem cell maintenance GO:0019827 130 0.111
myotube differentiation GO:0014902 105 0.111
cellular calcium ion homeostasis GO:0006874 119 0.111
regulation of transferase activity GO:0051338 263 0.111
regulation of interleukin 1 production GO:0032652 26 0.111
epithelial cell morphogenesis GO:0003382 41 0.111
regulation of nucleocytoplasmic transport GO:0046822 73 0.110
multi organism behavior GO:0051705 62 0.110
paramesonephric duct development GO:0061205 3 0.110
lipid localization GO:0010876 126 0.109
heart formation GO:0060914 16 0.109
atrioventricular node cell development GO:0060928 2 0.109
Mouse
endodermal cell fate determination GO:0007493 2 0.108
amino acid transport GO:0006865 61 0.108
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.108
positive regulation of lymphocyte activation GO:0051251 140 0.107
developmental maturation GO:0021700 193 0.107
regulation of body fluid levels GO:0050878 162 0.107
specification of organ identity GO:0010092 30 0.107
response to extracellular stimulus GO:0009991 127 0.107
cellular divalent inorganic cation homeostasis GO:0072503 127 0.106
ear morphogenesis GO:0042471 118 0.106
Mouse
ascending aorta morphogenesis GO:0035910 3 0.106
glandular epithelial cell differentiation GO:0002067 38 0.106
Mouse
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.106
leukocyte activation involved in immune response GO:0002366 126 0.106
positive regulation of cytokine biosynthetic process GO:0042108 40 0.106
ossification GO:0001503 216 0.105
cellular ion homeostasis GO:0006873 165 0.105
proepicardium development GO:0003342 2 0.105
Mouse
cell adhesion GO:0007155 329 0.105
mesonephric tubule formation GO:0072172 11 0.104
forebrain neuron differentiation GO:0021879 52 0.104
Mouse
branching involved in salivary gland morphogenesis GO:0060445 26 0.103
cartilage development GO:0051216 140 0.103
Mouse
positive regulation of secretion GO:0051047 130 0.101
i kappab kinase nf kappab signaling GO:0007249 85 0.100
mesoderm morphogenesis GO:0048332 64 0.100
forebrain morphogenesis GO:0048853 17 0.100
exocrine system development GO:0035272 45 0.100
single organism cell adhesion GO:0098602 156 0.100
interleukin 12 production GO:0032615 32 0.099
auditory receptor cell fate specification GO:0042667 1 0.099
spemann organizer formation GO:0060061 2 0.098
positive regulation of neuroblast proliferation GO:0002052 19 0.098
cell division GO:0051301 120 0.098
embryonic skeletal system development GO:0048706 120 0.098
Mouse
neural crest cell migration GO:0001755 32 0.098
nephron morphogenesis GO:0072028 69 0.097
cell fate commitment involved in pattern specification GO:0060581 14 0.097
Mouse
tumor necrosis factor production GO:0032640 50 0.097
interleukin 1 production GO:0032612 31 0.096
endocardial cell differentiation GO:0060956 4 0.096
regulation of humoral immune response GO:0002920 22 0.096
positive regulation of immune effector process GO:0002699 107 0.096
regulation of cell growth GO:0001558 91 0.096
cation transmembrane transport GO:0098655 266 0.095
Mouse
glucose metabolic process GO:0006006 92 0.095
t cell activation GO:0042110 289 0.095
digestion GO:0007586 40 0.095
nephric duct formation GO:0072179 4 0.094
regulation of interleukin 1 beta production GO:0032651 25 0.093
positive regulation of antimicrobial peptide production GO:0002225 1 0.093
positive regulation of interleukin 6 production GO:0032755 37 0.093
mesenchymal cell development GO:0014031 93 0.093
cell activation involved in immune response GO:0002263 126 0.092
response to decreased oxygen levels GO:0036293 59 0.092
signal transduction in absence of ligand GO:0038034 55 0.092
negative regulation of secretion by cell GO:1903531 54 0.092
regulation of cartilage development GO:0061035 44 0.091
Mouse
t cell proliferation GO:0042098 120 0.091
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.091
Mouse
negative regulation of catenin import into nucleus GO:0035414 2 0.090
cardiac atrium development GO:0003230 24 0.090
muscle fiber development GO:0048747 76 0.090
negative regulation of nervous system development GO:0051961 156 0.090
Mouse
salivary gland morphogenesis GO:0007435 33 0.089
regulation of cardiac muscle cell proliferation GO:0060043 23 0.089
Mouse
carbohydrate homeostasis GO:0033500 128 0.089
polarity specification of proximal distal axis GO:0010085 2 0.089
positive regulation of response to wounding GO:1903036 66 0.088
endocrine pancreas development GO:0031018 29 0.088
Mouse
chemotaxis GO:0006935 247 0.088
Mouse
negative regulation of wnt signaling pathway GO:0030178 73 0.088
Mouse
pallium development GO:0021543 120 0.087
Mouse
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.087
response to peptide GO:1901652 136 0.087
regulation of embryonic development GO:0045995 71 0.087
paraxial mesodermal cell fate commitment GO:0048343 2 0.087
actin cytoskeleton organization GO:0030036 220 0.087
Mouse
negative regulation of gliogenesis GO:0014014 23 0.086
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.086
embryonic heart tube morphogenesis GO:0003143 51 0.085
Mouse
calcium ion homeostasis GO:0055074 127 0.085
atrial cardiac muscle cell differentiation GO:0055011 2 0.085
Mouse
regulation of acute inflammatory response GO:0002673 27 0.085
lung alveolus development GO:0048286 45 0.085
Mouse

Nkx2-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org