Mus musculus

49 known processes

Nkx2-9

NK2 transcription factor related, locus 9 (Drosophila)

(Aliases: tinman,Nkx-2.9,Nkx2-8,Nkx2.9)

Nkx2-9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
forebrain development GO:0030900 302 0.797
Mouse
regionalization GO:0003002 337 0.781
Mouse
ion transmembrane transport GO:0034220 361 0.771
Mouse
cation transport GO:0006812 399 0.738
Mouse
telencephalon development GO:0021537 186 0.726
Mouse
epithelial tube morphogenesis GO:0060562 303 0.602
Mouse
negative regulation of cell proliferation GO:0008285 296 0.544
digestive tract development GO:0048565 190 0.505
Mouse Worm
pancreatic a cell fate commitment GO:0003326 2 0.480
Mouse
neuron projection guidance GO:0097485 141 0.473
Mouse
rhythmic process GO:0048511 174 0.472
Mouse
cation transmembrane transport GO:0098655 266 0.454
Mouse
epithelial cell development GO:0002064 159 0.451
Mouse
regulation of membrane potential GO:0042391 192 0.447
synaptic transmission GO:0007268 329 0.429
regulation of circadian rhythm GO:0042752 58 0.422
Mouse
embryonic organ morphogenesis GO:0048562 276 0.414
Mouse
regulation of ion transport GO:0043269 215 0.394
Mouse
regulation of system process GO:0044057 200 0.386
Mouse
cell fate commitment GO:0045165 210 0.384
Mouse
sensory organ morphogenesis GO:0090596 242 0.382
Mouse
regulation of neuron differentiation GO:0045664 281 0.379
Mouse
globus pallidus development GO:0021759 2 0.379
Mouse
skeletal system development GO:0001501 356 0.363
Mouse
gliogenesis GO:0042063 141 0.356
Mouse
camera type eye development GO:0043010 266 0.345
membrane depolarization GO:0051899 64 0.325
pancreatic pp cell fate commitment GO:0003329 2 0.322
Mouse
wnt signaling pathway GO:0016055 188 0.319
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.316
response to organonitrogen compound GO:0010243 246 0.313
germ cell development GO:0007281 185 0.312
developmental maturation GO:0021700 193 0.310
gland development GO:0048732 330 0.309
Mouse
pancreatic pp cell differentiation GO:0003312 2 0.308
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.306
endocrine system development GO:0035270 98 0.301
Mouse
spermatogenesis GO:0007283 284 0.301
somatotropin secreting cell differentiation GO:0060126 4 0.294
metencephalon development GO:0022037 89 0.291
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.289
diencephalon development GO:0021536 63 0.284
Mouse
regulation of cytokine production GO:0001817 266 0.283
amine metabolic process GO:0009308 45 0.282
stem cell development GO:0048864 219 0.278
regulation of cellular amino acid metabolic process GO:0006521 5 0.277
atrioventricular node cell development GO:0060928 2 0.277
Mouse
ventral spinal cord interneuron fate commitment GO:0060579 14 0.272
Mouse
negative regulation of defense response GO:0031348 77 0.263
transmembrane transport GO:0055085 412 0.248
Mouse
glial cell differentiation GO:0010001 131 0.245
Mouse
oligodendrocyte development GO:0014003 20 0.244
Mouse
negative regulation of nervous system development GO:0051961 156 0.235
Mouse
regulation of cell cycle GO:0051726 281 0.224
regulation of organ morphogenesis GO:2000027 144 0.218
spermatid development GO:0007286 108 0.217
cell fate determination involved in pattern specification GO:0060582 1 0.217
Mouse
auditory receptor cell fate determination GO:0042668 3 0.215
hindbrain development GO:0030902 128 0.212
glandular epithelial cell differentiation GO:0002067 38 0.210
Mouse
axon guidance GO:0007411 141 0.207
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.206
Mouse
forebrain neuron differentiation GO:0021879 52 0.204
Mouse
cerebral cortex cell migration GO:0021795 44 0.201
Mouse
axonogenesis GO:0007409 274 0.201
inorganic cation transmembrane transport GO:0098662 207 0.199
Mouse
cellular amino acid metabolic process GO:0006520 103 0.189
circadian rhythm GO:0007623 114 0.188
Mouse
meiotic cell cycle GO:0051321 122 0.186
atrioventricular node cell fate commitment GO:0060929 1 0.186
Mouse
cellular amine metabolic process GO:0044106 44 0.185
regulation of apoptotic signaling pathway GO:2001233 197 0.185
regulation of transmembrane transport GO:0034762 128 0.181
Mouse
histone modification GO:0016570 159 0.180
sensory perception of pain GO:0019233 47 0.180
neuromuscular process GO:0050905 99 0.178
cerebral cortex development GO:0021987 86 0.176
Mouse
cell fate specification GO:0001708 72 0.175
Mouse
astrocyte differentiation GO:0048708 43 0.174
Mouse
telencephalon cell migration GO:0022029 55 0.171
Mouse
cardiac pacemaker cell fate commitment GO:0060927 1 0.170
Mouse
nuclear division GO:0000280 158 0.169
ear morphogenesis GO:0042471 118 0.169
Mouse
regulation of postsynaptic membrane potential GO:0060078 48 0.167
chromatin organization GO:0006325 206 0.166
neuron migration GO:0001764 122 0.161
Mouse
neural precursor cell proliferation GO:0061351 121 0.161
connective tissue development GO:0061448 179 0.157
Mouse
digestive system development GO:0055123 200 0.154
Mouse Worm
negative regulation of cellular amine metabolic process GO:0033239 1 0.152
ossification GO:0001503 216 0.149
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.149
Mouse
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.149
Mouse
meiotic nuclear division GO:0007126 115 0.148
astrocyte fate commitment GO:0060018 4 0.148
multicellular organismal signaling GO:0035637 91 0.147
placenta development GO:0001890 140 0.145
stem cell differentiation GO:0048863 268 0.144
Mouse
chemotaxis GO:0006935 247 0.144
Mouse
epithelial tube formation GO:0072175 130 0.143
forebrain cell migration GO:0021885 58 0.143
Mouse
epidermis development GO:0008544 187 0.139
chondrocyte differentiation GO:0002062 72 0.139
Mouse
ear development GO:0043583 200 0.138
Mouse
neuroblast differentiation GO:0014016 2 0.137
epithelial cell proliferation GO:0050673 174 0.134
cell maturation GO:0048469 127 0.134
cerebral cortex radially oriented cell migration GO:0021799 31 0.133
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.133
cranial nerve development GO:0021545 41 0.132
menarche GO:0042696 1 0.128
Mouse
inner ear morphogenesis GO:0042472 101 0.128
erythrocyte differentiation GO:0030218 88 0.128
calcium ion transport GO:0006816 159 0.127
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.127
morphogenesis of embryonic epithelium GO:0016331 159 0.126
endocrine pancreas development GO:0031018 29 0.125
Mouse
autonomic nervous system development GO:0048483 43 0.124
cerebellum development GO:0021549 77 0.124
neuronal action potential GO:0019228 54 0.123
odontogenesis GO:0042476 78 0.123
Mouse
pallium development GO:0021543 120 0.121
Mouse
organelle fission GO:0048285 170 0.121
cell type specific apoptotic process GO:0097285 268 0.120
Mouse
dendrite development GO:0016358 115 0.119
kidney development GO:0001822 213 0.117
morphogenesis of a branching structure GO:0001763 203 0.117
purkinje myocyte differentiation GO:0003168 1 0.117
Mouse
limbic system development GO:0021761 72 0.117
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.116
neural nucleus development GO:0048857 22 0.116
Mouse
sensory perception GO:0007600 245 0.115
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.115
atrioventricular node cell differentiation GO:0060922 2 0.114
Mouse
regulation of neural retina development GO:0061074 3 0.114
forebrain neuron development GO:0021884 30 0.112
positive regulation of cell cycle GO:0045787 92 0.111
positive regulation of neuron differentiation GO:0045666 141 0.109
Mouse
skeletal system morphogenesis GO:0048705 203 0.108
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.108
Mouse
cerebellar cortex development GO:0021695 48 0.108
appendage morphogenesis GO:0035107 149 0.108
regulation of epidermal cell differentiation GO:0045604 21 0.107
organic anion transport GO:0015711 137 0.106
positive regulation of transcription via serum response element binding GO:0010735 1 0.106
Mouse
neuron fate specification GO:0048665 30 0.105
Mouse
hypophysis morphogenesis GO:0048850 3 0.105
appendage development GO:0048736 166 0.104
regulation of retina development in camera type eye GO:1902866 3 0.103
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.103
neural tube closure GO:0001843 90 0.102
multicellular organismal response to stress GO:0033555 62 0.101
regulation of interleukin 1 beta production GO:0032651 25 0.101
respiratory tube development GO:0030323 167 0.098
forebrain generation of neurons GO:0021872 63 0.098
Mouse
divalent metal ion transport GO:0070838 172 0.098
Mouse
limb morphogenesis GO:0035108 149 0.097
pulmonary myocardium development GO:0003350 3 0.097
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.096
negative regulation of cell development GO:0010721 169 0.096
Mouse
sclerotome development GO:0061056 4 0.095
cardiac right ventricle formation GO:0003219 3 0.094
phenol containing compound metabolic process GO:0018958 60 0.094
neurotransmitter transport GO:0006836 76 0.093
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.093
regulation of gliogenesis GO:0014013 50 0.092
Mouse
nucleoside phosphate biosynthetic process GO:1901293 79 0.092
mesoderm formation GO:0001707 62 0.091
regulation of cardioblast differentiation GO:0051890 3 0.091
Mouse
nucleotide metabolic process GO:0009117 332 0.090
cellular ketone metabolic process GO:0042180 84 0.090
phenol containing compound biosynthetic process GO:0046189 21 0.090
hair cell differentiation GO:0035315 40 0.089
inflammatory response GO:0006954 244 0.089
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.089
response to radiation GO:0009314 165 0.089
inner ear receptor cell differentiation GO:0060113 61 0.088
regulation of blood circulation GO:1903522 93 0.088
Mouse
positive regulation of cell development GO:0010720 237 0.087
Mouse
neural tube formation GO:0001841 108 0.086
adenohypophysis development GO:0021984 14 0.086
glial cell fate commitment GO:0021781 14 0.086
Mouse
male gamete generation GO:0048232 285 0.086
acetylcholine transport GO:0015870 2 0.085
leukocyte differentiation GO:0002521 342 0.085
Mouse
transmission of nerve impulse GO:0019226 76 0.085
pancreas development GO:0031016 57 0.085
Mouse
regulation of secretion GO:0051046 274 0.084
mesoderm development GO:0007498 100 0.084
cytoplasmic transport GO:0016482 234 0.083
action potential GO:0001508 78 0.083
negative regulation of intracellular signal transduction GO:1902532 167 0.082
heart morphogenesis GO:0003007 178 0.082
Mouse
metanephros development GO:0001656 79 0.082
anion transport GO:0006820 177 0.081
formation of primary germ layer GO:0001704 77 0.081
embryonic epithelial tube formation GO:0001838 130 0.081
neural tube development GO:0021915 160 0.081
embryonic digit morphogenesis GO:0042733 56 0.080
organic hydroxy compound transport GO:0015850 93 0.079
nucleobase containing small molecule metabolic process GO:0055086 352 0.079
chromatin modification GO:0016568 187 0.079
metal ion homeostasis GO:0055065 189 0.079
regulation of camp metabolic process GO:0030814 30 0.079
auditory receptor cell fate specification GO:0042667 1 0.079
cytokine production GO:0001816 319 0.079
mesoderm morphogenesis GO:0048332 64 0.078
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.078
midbrain development GO:0030901 35 0.078
renal tubule morphogenesis GO:0061333 72 0.078
regulation of binding GO:0051098 111 0.078
ventral spinal cord interneuron fate determination GO:0060580 1 0.078
Mouse
segmentation GO:0035282 93 0.077
mechanoreceptor differentiation GO:0042490 67 0.077
negative regulation of myeloid cell differentiation GO:0045638 38 0.076
organic hydroxy compound metabolic process GO:1901615 203 0.076
cation homeostasis GO:0055080 212 0.075
nerve development GO:0021675 67 0.075
urogenital system development GO:0001655 261 0.075
muscle tissue development GO:0060537 308 0.075
Mouse
regulation of organ formation GO:0003156 34 0.075
nephron development GO:0072006 109 0.074
t cell proliferation GO:0042098 120 0.074
pancreatic a cell differentiation GO:0003310 7 0.074
Mouse
cognition GO:0050890 149 0.074
regulation of defense response GO:0031347 233 0.073
limb development GO:0060173 166 0.073
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.073
regulation of secretion by cell GO:1903530 249 0.073
regulation of cell migration GO:0030334 219 0.072
positive regulation of nervous system development GO:0051962 221 0.071
Mouse
positive regulation of glial cell differentiation GO:0045687 21 0.071
Mouse
actomyosin structure organization GO:0031032 56 0.071
Mouse
regulation of histone modification GO:0031056 56 0.071
hair follicle morphogenesis GO:0031069 29 0.071
spermatid differentiation GO:0048515 115 0.071
positive regulation of stem cell differentiation GO:2000738 23 0.071
Mouse
pituitary gland development GO:0021983 38 0.071
Mouse
regulation of glial cell differentiation GO:0045685 41 0.071
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.070
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.070
regulation of cellular component biogenesis GO:0044087 181 0.069
Mouse
positive regulation of organelle organization GO:0010638 128 0.069
mesenchyme development GO:0060485 152 0.069
Mouse
carbohydrate metabolic process GO:0005975 230 0.069
cardiac chamber development GO:0003205 108 0.068
Mouse
enteroendocrine cell differentiation GO:0035883 16 0.068
Mouse
reproductive behavior GO:0019098 32 0.068
cellular ion homeostasis GO:0006873 165 0.067
peptidyl lysine modification GO:0018205 77 0.066
deltoid tuberosity development GO:0035993 3 0.066
brain morphogenesis GO:0048854 32 0.066
primary neural tube formation GO:0014020 95 0.065
determination of left right symmetry GO:0007368 80 0.065
Mouse
camp biosynthetic process GO:0006171 31 0.065
paraxial mesodermal cell differentiation GO:0048342 2 0.064
multi organism behavior GO:0051705 62 0.064
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.063
Mouse
nitrogen compound transport GO:0071705 271 0.063
catecholamine metabolic process GO:0006584 30 0.063
cardiac chamber morphogenesis GO:0003206 93 0.063
Mouse
hypothalamus cell differentiation GO:0021979 8 0.062
multicellular organism growth GO:0035264 161 0.062
regulation of organelle organization GO:0033043 289 0.061
alpha amino acid metabolic process GO:1901605 59 0.060
cell recognition GO:0008037 83 0.060
glucose homeostasis GO:0042593 128 0.060
response to decreased oxygen levels GO:0036293 59 0.060
stem cell maintenance GO:0019827 130 0.060
positive regulation of secretion GO:0051047 130 0.060
central nervous system neuron development GO:0021954 67 0.059
visceral serous pericardium development GO:0061032 2 0.059
plasma cell differentiation GO:0002317 3 0.059
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 0.059
cell division GO:0051301 120 0.059
cellular calcium ion homeostasis GO:0006874 119 0.059
negative regulation of molecular function GO:0044092 258 0.058
learning GO:0007612 98 0.058
positive regulation of protein phosphorylation GO:0001934 242 0.057
glial cell fate specification GO:0021780 5 0.057
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.057
homeostasis of number of cells GO:0048872 210 0.057
Mouse
divalent inorganic cation transport GO:0072511 178 0.057
Mouse
heart process GO:0003015 94 0.057
Mouse
cardiocyte differentiation GO:0035051 87 0.057
Mouse
gastrulation GO:0007369 116 0.056
tube closure GO:0060606 91 0.056
intestinal epithelial structure maintenance GO:0060729 4 0.056
skeletal muscle cell differentiation GO:0035914 66 0.056
negative regulation of protein modification process GO:0031400 163 0.056
hindbrain morphogenesis GO:0021575 46 0.056
nucleotide biosynthetic process GO:0009165 78 0.056
regulation of ion transmembrane transporter activity GO:0032412 54 0.056
Mouse
organ growth GO:0035265 117 0.056
Mouse
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.055
Mouse
regulation of mast cell differentiation GO:0060375 3 0.055
carbohydrate homeostasis GO:0033500 128 0.055
lymphocyte proliferation GO:0046651 164 0.055
regulation of cell motility GO:2000145 236 0.055
response to organic cyclic compound GO:0014070 198 0.054
regulation of synaptic plasticity GO:0048167 87 0.054
auditory receptor cell differentiation GO:0042491 37 0.054
peptidyl amino acid modification GO:0018193 336 0.054
negative regulation of protein phosphorylation GO:0001933 126 0.053
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.053
embryonic appendage morphogenesis GO:0035113 126 0.053
hemangioblast cell differentiation GO:0060217 1 0.053
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.053
cell proliferation involved in heart valve development GO:2000793 2 0.053
organonitrogen compound biosynthetic process GO:1901566 192 0.052
canonical wnt signaling pathway GO:0060070 130 0.052
Mouse
protein localization to organelle GO:0033365 185 0.052
respiratory gaseous exchange GO:0007585 43 0.052
regulation of cell cycle process GO:0010564 160 0.051
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.051
negative regulation of inflammatory response GO:0050728 61 0.051
cellular chemical homeostasis GO:0055082 215 0.051
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.051
oxidation reduction process GO:0055114 342 0.051
ribonucleotide metabolic process GO:0009259 291 0.050
negative regulation of phosphorylation GO:0042326 166 0.050
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.050
respiratory system development GO:0060541 190 0.050
regulation of meiotic cell cycle GO:0051445 34 0.050
synapse organization GO:0050808 125 0.050
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.050
cardiac ventricle development GO:0003231 83 0.050
Mouse
hair follicle development GO:0001942 85 0.050
striated muscle tissue development GO:0014706 293 0.049
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.049
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.049
myeloid cell differentiation GO:0030099 233 0.049
Mouse
negative regulation of immune system process GO:0002683 209 0.049
spinal cord patterning GO:0021511 25 0.049
Mouse
nephron morphogenesis GO:0072028 69 0.049
regulation of neuron projection development GO:0010975 169 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.049
mitotic cell cycle GO:0000278 195 0.049
regulation of dna binding GO:0051101 39 0.049
mesenchymal cell development GO:0014031 93 0.048
regulation of epidermis development GO:0045682 33 0.048
neuromuscular process controlling balance GO:0050885 59 0.048
positive regulation of growth GO:0045927 104 0.047
cardiac muscle tissue development GO:0048738 130 0.047
Mouse
microtubule based process GO:0007017 236 0.047
leukocyte proliferation GO:0070661 172 0.047
mesonephric epithelium development GO:0072163 94 0.047
monoamine transport GO:0015844 33 0.046
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.046
semaphorin plexin signaling pathway GO:0071526 21 0.046
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.046
Mouse
oligodendrocyte cell fate specification GO:0021778 5 0.046
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.046
Mouse
regulation of stem cell differentiation GO:2000736 50 0.046
Mouse
apoptotic process involved in morphogenesis GO:0060561 25 0.046
Mouse
atrial cardiac muscle cell development GO:0055014 2 0.046
Mouse
tube formation GO:0035148 140 0.046
kidney morphogenesis GO:0060993 83 0.045
aortic valve morphogenesis GO:0003180 4 0.045
peptide secretion GO:0002790 114 0.045
purine containing compound metabolic process GO:0072521 311 0.044
peripheral nervous system development GO:0007422 53 0.044
transdifferentiation GO:0060290 1 0.044
positive regulation of programmed cell death GO:0043068 218 0.044
nephron tubule development GO:0072080 84 0.044
sensory system development GO:0048880 3 0.044
nuclear transport GO:0051169 139 0.044
ectoderm formation GO:0001705 3 0.044
mesonephric tubule development GO:0072164 94 0.043
monocarboxylic acid metabolic process GO:0032787 191 0.043
apoptotic signaling pathway GO:0097190 306 0.043
negative regulation of cellular component organization GO:0051129 194 0.043
covalent chromatin modification GO:0016569 163 0.043
central nervous system neuron differentiation GO:0021953 162 0.042
Zebrafish Mouse
lens development in camera type eye GO:0002088 62 0.042
lens morphogenesis in camera type eye GO:0002089 24 0.042
neural retina development GO:0003407 41 0.042
positive regulation of mapk cascade GO:0043410 170 0.042
positive regulation of camp mediated signaling GO:0043950 3 0.042
bone development GO:0060348 120 0.042
motor neuron axon guidance GO:0008045 26 0.042
norepinephrine transport GO:0015874 2 0.041
cyclic purine nucleotide metabolic process GO:0052652 43 0.041
body fluid secretion GO:0007589 53 0.041
face development GO:0060324 38 0.041
positive regulation of epithelial cell proliferation GO:0050679 68 0.041
type b pancreatic cell fate commitment GO:0003327 1 0.041
Mouse
protein localization to nucleus GO:0034504 121 0.040
digestive tract morphogenesis GO:0048546 147 0.040
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.040
Mouse
embryonic limb morphogenesis GO:0030326 126 0.040
purine nucleotide biosynthetic process GO:0006164 65 0.040
embryonic heart tube formation GO:0003144 1 0.040
epithelial cell morphogenesis GO:0003382 41 0.040
mesodermal cell differentiation GO:0048333 22 0.040
optic nerve development GO:0021554 8 0.040
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.040
positive regulation of apoptotic process GO:0043065 217 0.040
cytokine mediated signaling pathway GO:0019221 115 0.040
mesonephros development GO:0001823 97 0.040
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.040
Mouse
extracellular matrix organization GO:0030198 147 0.039
bmp signaling pathway GO:0030509 93 0.039
Mouse
alpha beta t cell activation GO:0046631 91 0.039
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.039
circadian sleep wake cycle rem sleep GO:0042747 1 0.039
extracellular structure organization GO:0043062 148 0.039
clara cell differentiation GO:0060486 4 0.039
Mouse
lateral inhibition GO:0046331 1 0.039
cardiac septum development GO:0003279 59 0.039
somatotropin secreting cell development GO:0060133 2 0.039
hypothalamus development GO:0021854 16 0.039
Mouse
negative regulation of secretion GO:0051048 61 0.039
meiotic cell cycle process GO:1903046 77 0.039
spinal cord dorsal ventral patterning GO:0021513 23 0.039
Mouse
membrane organization GO:0061024 245 0.038
ventral spinal cord interneuron differentiation GO:0021514 16 0.038
Zebrafish Mouse
cell fate commitment involved in pattern specification GO:0060581 14 0.038
Mouse
purine ribonucleotide biosynthetic process GO:0009152 59 0.038
oligodendrocyte cell fate commitment GO:0021779 5 0.038
Mouse
regulation of ossification GO:0030278 112 0.038
positive regulation of interleukin 1 alpha production GO:0032730 4 0.038
regulation of cell projection organization GO:0031344 206 0.038
learning or memory GO:0007611 148 0.038
cell proliferation in external granule layer GO:0021924 10 0.038
development of primary sexual characteristics GO:0045137 143 0.037
Mouse
neurohypophysis development GO:0021985 2 0.037
response to light stimulus GO:0009416 135 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
skin development GO:0043588 220 0.037
regulation of chromatin organization GO:1902275 57 0.037
extrinsic apoptotic signaling pathway GO:0097191 126 0.037
tendon cell differentiation GO:0035990 4 0.036
embryonic skeletal system morphogenesis GO:0048704 91 0.036
locomotory behavior GO:0007626 195 0.036
Mouse
cell differentiation involved in kidney development GO:0061005 33 0.036
proepicardium development GO:0003342 2 0.036
Mouse
regulation of neuron death GO:1901214 134 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.036
tendon formation GO:0035992 4 0.035
ensheathment of neurons GO:0007272 76 0.035
exploration behavior GO:0035640 21 0.035
muscle cell differentiation GO:0042692 261 0.035
Mouse
intracellular protein transport GO:0006886 204 0.035
cellular carbohydrate metabolic process GO:0044262 119 0.035
negative regulation of secretion by cell GO:1903531 54 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
response to peptide GO:1901652 136 0.035
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.035
lateral geniculate nucleus development GO:0021771 1 0.035
heart formation GO:0060914 16 0.034
ureteric bud development GO:0001657 94 0.034
sodium ion transport GO:0006814 73 0.034
Mouse
epithelial cell fate commitment GO:0072148 13 0.034
Mouse
cerebellar cortex formation GO:0021697 22 0.034
organelle localization GO:0051640 179 0.034
spinal cord development GO:0021510 81 0.034
Zebrafish Mouse
regulation of ion transmembrane transport GO:0034765 119 0.034
Mouse
cellular homeostasis GO:0019725 240 0.034
generation of ovulation cycle rhythm GO:0060112 1 0.034
regulation of homeostatic process GO:0032844 182 0.034
hematopoietic stem cell differentiation GO:0060218 8 0.034
intracellular distribution of mitochondria GO:0048312 1 0.034
regulation of reproductive process GO:2000241 66 0.034
regulation of mitotic cell cycle GO:0007346 126 0.033
regulation of leukocyte proliferation GO:0070663 121 0.033
dopamine catabolic process GO:0042420 4 0.033
lung development GO:0030324 164 0.033
regulation of transporter activity GO:0032409 57 0.033
Mouse
mitochondrion organization GO:0007005 134 0.033
regulation of alpha beta t cell activation GO:0046634 53 0.033
lymphocyte differentiation GO:0030098 242 0.033
Mouse
regulation of protein localization GO:0032880 231 0.033
ras protein signal transduction GO:0007265 77 0.032
organic hydroxy compound biosynthetic process GO:1901617 77 0.032
positive regulation of synaptic plasticity GO:0031915 4 0.032
positive regulation of cell motility GO:2000147 116 0.032
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.032
kidney epithelium development GO:0072073 121 0.032
positive regulation of kidney development GO:0090184 28 0.032
regulation of chromatin modification GO:1903308 57 0.032
lung cell differentiation GO:0060479 30 0.032
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.032
positive regulation of homeostatic process GO:0032846 64 0.032
negative regulation of cell cycle GO:0045786 123 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
cellular response to abiotic stimulus GO:0071214 56 0.031
somite development GO:0061053 81 0.031
regulation of heart morphogenesis GO:2000826 22 0.031
hindlimb morphogenesis GO:0035137 42 0.031
regulation of auditory receptor cell differentiation GO:0045607 4 0.031
regulation of nuclear division GO:0051783 56 0.031
regulation of isoprenoid metabolic process GO:0019747 1 0.031

Nkx2-9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.043
bone disease DOID:0080001 0 0.038
musculoskeletal system disease DOID:17 0 0.038
connective tissue disease DOID:65 0 0.038