Mus musculus

111 known processes

Nlrp6

NLR family, pyrin domain containing 6

(Aliases: Pypaf5,Navr/Avr,Nalp6,AI504961)

Nlrp6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anion transport GO:0006820 177 0.414
organic cyclic compound catabolic process GO:1901361 295 0.407
nucleoside phosphate metabolic process GO:0006753 338 0.328
organic acid transport GO:0015849 101 0.323
defense response to other organism GO:0098542 197 0.312
Mouse
cellular lipid metabolic process GO:0044255 323 0.264
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.239
regulation of defense response GO:0031347 233 0.236
organic hydroxy compound metabolic process GO:1901615 203 0.228
defense response to bacterium GO:0042742 119 0.227
Mouse
activation of immune response GO:0002253 138 0.220
regulation of body fluid levels GO:0050878 162 0.200
aromatic compound catabolic process GO:0019439 286 0.199
diterpenoid metabolic process GO:0016101 24 0.192
nitrogen compound transport GO:0071705 271 0.172
purine nucleotide metabolic process GO:0006163 302 0.165
ras protein signal transduction GO:0007265 77 0.162
nucleoside triphosphate metabolic process GO:0009141 230 0.159
immune effector process GO:0002252 321 0.159
Mouse
organic anion transport GO:0015711 137 0.156
small molecule biosynthetic process GO:0044283 132 0.148
nucleotide metabolic process GO:0009117 332 0.144
cellular nitrogen compound catabolic process GO:0044270 280 0.144
regulation of hydrolase activity GO:0051336 246 0.143
Mouse
inflammatory response GO:0006954 244 0.131
organonitrogen compound biosynthetic process GO:1901566 192 0.128
Mouse
purine containing compound metabolic process GO:0072521 311 0.126
regulation of cell migration GO:0030334 219 0.124
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.118
divalent inorganic cation transport GO:0072511 178 0.117
amine metabolic process GO:0009308 45 0.116
lipid biosynthetic process GO:0008610 179 0.115
response to organonitrogen compound GO:0010243 246 0.112
Mouse
wound healing GO:0042060 157 0.111
ribonucleotide metabolic process GO:0009259 291 0.109
nucleoside metabolic process GO:0009116 246 0.108
positive regulation of cell death GO:0010942 224 0.107
Mouse
positive regulation of programmed cell death GO:0043068 218 0.107
Mouse
cation transport GO:0006812 399 0.107
response to lipopolysaccharide GO:0032496 128 0.105
Mouse
rho protein signal transduction GO:0007266 32 0.103
alcohol metabolic process GO:0006066 116 0.102
skin development GO:0043588 220 0.101
monocarboxylic acid transport GO:0015718 44 0.100
negative regulation of cellular protein metabolic process GO:0032269 247 0.100
cytokine production GO:0001816 319 0.098
Mouse
heterocycle catabolic process GO:0046700 280 0.097
purine ribonucleotide metabolic process GO:0009150 290 0.097
purine ribonucleoside metabolic process GO:0046128 241 0.095
lipid localization GO:0010876 126 0.095
leukocyte differentiation GO:0002521 342 0.093
purine nucleoside triphosphate catabolic process GO:0009146 203 0.092
organonitrogen compound catabolic process GO:1901565 264 0.089
response to acid chemical GO:0001101 111 0.089
calcium ion transport GO:0006816 159 0.086
regulation of protein kinase activity GO:0045859 232 0.085
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.085
myeloid cell differentiation GO:0030099 233 0.084
cellular amino acid metabolic process GO:0006520 103 0.081
carboxylic acid transport GO:0046942 100 0.080
retinoid metabolic process GO:0001523 24 0.080
positive regulation of cytokine production GO:0001819 174 0.079
Mouse
regulation of ion transport GO:0043269 215 0.078
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.077
anion transmembrane transport GO:0098656 71 0.077
response to inorganic substance GO:0010035 96 0.076
carbohydrate metabolic process GO:0005975 230 0.075
nucleoside triphosphate catabolic process GO:0009143 205 0.075
positive regulation of apoptotic process GO:0043065 217 0.074
Mouse
activation of innate immune response GO:0002218 56 0.071
maintenance of location GO:0051235 89 0.071
glycosyl compound metabolic process GO:1901657 246 0.070
lipid transport GO:0006869 98 0.067
ribose phosphate metabolic process GO:0019693 291 0.066
oxidation reduction process GO:0055114 342 0.066
Mouse
innate immune response GO:0045087 157 0.066
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.066
negative regulation of protein modification process GO:0031400 163 0.065
cellular ketone metabolic process GO:0042180 84 0.065
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.065
purine containing compound catabolic process GO:0072523 213 0.062
cellular response to lipopolysaccharide GO:0071222 77 0.061
negative regulation of intracellular signal transduction GO:1902532 167 0.061
steroid metabolic process GO:0008202 119 0.059
purine nucleoside metabolic process GO:0042278 241 0.059
interferon beta production GO:0032608 16 0.059
sulfur compound metabolic process GO:0006790 100 0.059
regulation of hormone levels GO:0010817 211 0.058
negative regulation of protein metabolic process GO:0051248 282 0.056
actin polymerization or depolymerization GO:0008154 54 0.056
spermatid development GO:0007286 108 0.056
ribonucleotide catabolic process GO:0009261 208 0.056
organophosphate catabolic process GO:0046434 232 0.056
cellular response to lipid GO:0071396 145 0.055
regulation of apoptotic signaling pathway GO:2001233 197 0.055
negative regulation of protein phosphorylation GO:0001933 126 0.054
apoptotic signaling pathway GO:0097190 306 0.054
purine ribonucleotide catabolic process GO:0009154 208 0.054
cellular response to inorganic substance GO:0071241 37 0.054
purine nucleoside triphosphate metabolic process GO:0009144 226 0.053
actin filament organization GO:0007015 113 0.052
nucleoside catabolic process GO:0009164 206 0.052
isoprenoid metabolic process GO:0006720 29 0.051
protein processing GO:0016485 163 0.051
Mouse
ribonucleoside metabolic process GO:0009119 245 0.051
regulation of actin cytoskeleton organization GO:0032956 84 0.051
multicellular organism growth GO:0035264 161 0.050
regulation of lymphocyte proliferation GO:0050670 117 0.050
ribonucleoside triphosphate metabolic process GO:0009199 220 0.050
learning or memory GO:0007611 148 0.050
monocarboxylic acid biosynthetic process GO:0072330 61 0.049
purine nucleoside catabolic process GO:0006152 205 0.049
regulation of cell activation GO:0050865 289 0.049
negative regulation of phosphate metabolic process GO:0045936 184 0.048
glycosyl compound catabolic process GO:1901658 206 0.048
cation transmembrane transport GO:0098655 266 0.048
positive regulation of defense response GO:0031349 124 0.048
leukocyte proliferation GO:0070661 172 0.048
diterpenoid biosynthetic process GO:0016102 7 0.047
cellular amine metabolic process GO:0044106 44 0.046
negative regulation of phosphorylation GO:0042326 166 0.046
positive regulation of cell motility GO:2000147 116 0.046
rac protein signal transduction GO:0016601 13 0.046
regulation of actin filament based process GO:0032970 99 0.046
cellular chemical homeostasis GO:0055082 215 0.045
negative regulation of immune system process GO:0002683 209 0.045
regulation of cell motility GO:2000145 236 0.045
Mouse
regulation of cytokine production GO:0001817 266 0.044
Mouse
terpenoid metabolic process GO:0006721 25 0.044
carboxylic acid biosynthetic process GO:0046394 86 0.043
regulation of interleukin 10 secretion GO:2001179 4 0.043
response to radiation GO:0009314 165 0.043
regulation of cytoskeleton organization GO:0051493 122 0.043
t cell activation GO:0042110 289 0.043
cellular homeostasis GO:0019725 240 0.043
angiogenesis GO:0001525 201 0.043
small gtpase mediated signal transduction GO:0007264 97 0.042
negative regulation of cellular amine metabolic process GO:0033239 1 0.042
intrinsic apoptotic signaling pathway GO:0097193 132 0.042
lymphocyte proliferation GO:0046651 164 0.042
regulation of secretion by cell GO:1903530 249 0.042
Mouse
sensory perception GO:0007600 245 0.041
organic hydroxy compound biosynthetic process GO:1901617 77 0.041
organic acid biosynthetic process GO:0016053 86 0.041
response to molecule of bacterial origin GO:0002237 143 0.041
Mouse
negative regulation of kinase activity GO:0033673 81 0.040
sodium ion transport GO:0006814 73 0.040
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.040
Mouse
regulation of t cell activation GO:0050863 170 0.040
positive regulation of apoptotic signaling pathway GO:2001235 95 0.040
regulation of leukocyte proliferation GO:0070663 121 0.040
response to drug GO:0042493 75 0.039
transmembrane transport GO:0055085 412 0.039
regulation of lymphocyte activation GO:0051249 240 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.039
adaptive immune response GO:0002250 155 0.038
Mouse
ribonucleoside catabolic process GO:0042454 206 0.038
isoprenoid biosynthetic process GO:0008299 9 0.038
response to organic cyclic compound GO:0014070 198 0.038
Mouse
glycoprotein metabolic process GO:0009100 116 0.037
ossification GO:0001503 216 0.037
actin cytoskeleton organization GO:0030036 220 0.037
organic hydroxy compound transport GO:0015850 93 0.037
nucleotide catabolic process GO:0009166 217 0.037
regulation of multi organism process GO:0043900 111 0.037
Mouse
lipid homeostasis GO:0055088 63 0.036
regulation of actin filament length GO:0030832 45 0.036
fatty acid metabolic process GO:0006631 121 0.036
negative regulation of molecular function GO:0044092 258 0.036
Mouse
t cell proliferation GO:0042098 120 0.035
gland development GO:0048732 330 0.034
reactive oxygen species metabolic process GO:0072593 84 0.034
positive regulation of lymphocyte activation GO:0051251 140 0.034
protein polymerization GO:0051258 57 0.034
posttranscriptional regulation of gene expression GO:0010608 155 0.034
Mouse
response to oxidative stress GO:0006979 123 0.033
short chain fatty acid catabolic process GO:0019626 2 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.033
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.032
negative regulation of transferase activity GO:0051348 85 0.032
succinate transport GO:0015744 1 0.032
lipid catabolic process GO:0016042 69 0.032
mitochondrion organization GO:0007005 134 0.032
carbohydrate derivative catabolic process GO:1901136 231 0.031
cytoplasmic transport GO:0016482 234 0.031
response to metal ion GO:0010038 47 0.031
nucleoside monophosphate metabolic process GO:0009123 85 0.031
regulation of metal ion transport GO:0010959 106 0.031
regulation of t cell proliferation GO:0042129 92 0.030
cellular alcohol metabolic process GO:0044107 3 0.030
regulation of nucleotide catabolic process GO:0030811 122 0.030
spermatid differentiation GO:0048515 115 0.030
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
negative regulation of growth GO:0045926 99 0.030
Mouse
positive regulation of response to wounding GO:1903036 66 0.030
hormone metabolic process GO:0042445 86 0.030
macromolecule catabolic process GO:0009057 281 0.029
carnitine transport GO:0015879 3 0.029
organophosphate biosynthetic process GO:0090407 122 0.029
coagulation GO:0050817 78 0.029
cellular calcium ion homeostasis GO:0006874 119 0.029
cellular lipid catabolic process GO:0044242 52 0.029
regulation of actin polymerization or depolymerization GO:0008064 45 0.028
cellular amino acid catabolic process GO:0009063 25 0.028
regulation of response to wounding GO:1903034 189 0.028
endocytosis GO:0006897 168 0.028
Mouse
regulation of kinase activity GO:0043549 249 0.028
Mouse
regulation of response to biotic stimulus GO:0002831 38 0.028
Mouse
regulation of protein transport GO:0051223 163 0.028
Mouse
homeostasis of number of cells GO:0048872 210 0.028
regulation of inflammatory response GO:0050727 147 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
gtp metabolic process GO:0046039 144 0.027
defense response to virus GO:0051607 68 0.027
Mouse
regulation of cellular component size GO:0032535 121 0.027
vitamin d3 metabolic process GO:0070640 3 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.027
regulation of proteolysis GO:0030162 164 0.027
Mouse
alcohol biosynthetic process GO:0046165 43 0.027
axonogenesis GO:0007409 274 0.027
leukocyte migration GO:0050900 124 0.027
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.026
cholesterol transport GO:0030301 38 0.026
skeletal system development GO:0001501 356 0.026
lipid storage GO:0019915 36 0.026
fat soluble vitamin biosynthetic process GO:0042362 4 0.026
peptide transport GO:0015833 133 0.025
negative regulation of lymphocyte proliferation GO:0050672 45 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
cellular response to abiotic stimulus GO:0071214 56 0.025
cellular ion homeostasis GO:0006873 165 0.025
cellular response to peptidoglycan GO:0071224 4 0.024
Mouse
regulation of anatomical structure size GO:0090066 178 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
actin filament polymerization GO:0030041 44 0.024
toxin transport GO:1901998 38 0.024
forebrain development GO:0030900 302 0.024
protein maturation GO:0051604 176 0.024
Mouse
glucose homeostasis GO:0042593 128 0.024
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.024
Mouse
response to decreased oxygen levels GO:0036293 59 0.024
urogenital system development GO:0001655 261 0.024
regulation of tumor necrosis factor production GO:0032680 49 0.024
Mouse
multicellular organismal homeostasis GO:0048871 164 0.024
peptidyl amino acid modification GO:0018193 336 0.023
Mouse
naphthalene metabolic process GO:0018931 1 0.023
cellular response to molecule of bacterial origin GO:0071219 83 0.023
Mouse
glucose transport GO:0015758 56 0.023
negative regulation of cytokine production GO:0001818 84 0.023
Mouse
interleukin 8 production GO:0032637 4 0.023
terpenoid biosynthetic process GO:0016114 7 0.023
defense response to gram negative bacterium GO:0050829 28 0.023
regulation of nucleotide metabolic process GO:0006140 169 0.023
inorganic anion transmembrane transport GO:0098661 29 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
immune response activating signal transduction GO:0002757 116 0.023
positive regulation of protein transport GO:0051222 93 0.022
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
positive regulation of interleukin 8 production GO:0032757 2 0.022
regulation of gtp catabolic process GO:0033124 113 0.022
inorganic anion transport GO:0015698 43 0.022
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
release of cytochrome c from mitochondria GO:0001836 23 0.022
positive regulation of innate immune response GO:0045089 80 0.022
regulation of wound healing GO:0061041 40 0.022
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.022
Mouse
carbohydrate homeostasis GO:0033500 128 0.022
second messenger mediated signaling GO:0019932 73 0.022
regulation of protein localization GO:0032880 231 0.021
Mouse
epithelial cell development GO:0002064 159 0.021
regulation of myeloid cell differentiation GO:0045637 96 0.021
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.021
male gamete generation GO:0048232 285 0.021
negative regulation of t cell activation GO:0050868 65 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
positive regulation of secretion by cell GO:1903532 114 0.021
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.021
antigen processing and presentation of peptide antigen GO:0048002 29 0.021
epithelial tube morphogenesis GO:0060562 303 0.021
alpha amino acid metabolic process GO:1901605 59 0.020
blood coagulation GO:0007596 76 0.020
norepinephrine transport GO:0015874 2 0.020
regulation of interleukin 6 production GO:0032675 55 0.020
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.020
inter male aggressive behavior GO:0002121 3 0.020
cellular response to oxidative stress GO:0034599 76 0.020
regulation of rho protein signal transduction GO:0035023 71 0.020
positive regulation of proteolysis GO:0045862 85 0.020
Mouse
multicellular organismal aging GO:0010259 24 0.020
small molecule catabolic process GO:0044282 71 0.020
vitamin a metabolic process GO:0006776 2 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
positive regulation of cytokine secretion GO:0050715 41 0.019
Mouse
response to light stimulus GO:0009416 135 0.019
negative regulation of lymphocyte activation GO:0051250 91 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.019
regulation of actin filament polymerization GO:0030833 38 0.019
sensory organ morphogenesis GO:0090596 242 0.019
hormone secretion GO:0046879 128 0.019
cell adhesion GO:0007155 329 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
aromatic amino acid family catabolic process GO:0009074 4 0.019
dendrite development GO:0016358 115 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
regulation of coagulation GO:0050818 31 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
response to extracellular stimulus GO:0009991 127 0.019
positive regulation of interleukin 8 secretion GO:2000484 1 0.019
regulation of intracellular protein transport GO:0033157 82 0.019
response to nutrient levels GO:0031667 109 0.019
positive regulation of secretion GO:0051047 130 0.019
Mouse
blood vessel morphogenesis GO:0048514 285 0.018
regulation of vasculature development GO:1901342 88 0.018
positive regulation of protein modification process GO:0031401 299 0.018
Mouse
regulation of organelle organization GO:0033043 289 0.018
ion transmembrane transport GO:0034220 361 0.018
negative regulation of cell cycle GO:0045786 123 0.018
regulation of lipid transport GO:0032368 36 0.018
calcitriol biosynthetic process from calciol GO:0036378 3 0.018
regulation of peptidase activity GO:0052547 96 0.018
Mouse
response to peptide hormone GO:0043434 127 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
sterol transport GO:0015918 38 0.018
pigment metabolic process GO:0042440 32 0.018
positive regulation of cell migration GO:0030335 109 0.018
apoptotic mitochondrial changes GO:0008637 48 0.018
cellular component disassembly involved in execution phase of apoptosis GO:0006921 9 0.018
cellular response to biotic stimulus GO:0071216 92 0.018
Mouse
negative regulation of keratinocyte differentiation GO:0045617 4 0.017
cell fate commitment GO:0045165 210 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
apoptotic nuclear changes GO:0030262 9 0.017
positive regulation of homeostatic process GO:0032846 64 0.017
hemostasis GO:0007599 78 0.017
oxidative demethylation GO:0070989 1 0.017
response to uv GO:0009411 44 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.017
Mouse
germ cell development GO:0007281 185 0.017
erythrocyte differentiation GO:0030218 88 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.017
Mouse
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.016
respiratory tube development GO:0030323 167 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
positive regulation of ion transport GO:0043270 65 0.016
growth of symbiont involved in interaction with host GO:0044116 23 0.016
Mouse
glial cell differentiation GO:0010001 131 0.016
amide transport GO:0042886 138 0.016
positive regulation of interleukin 10 production GO:0032733 12 0.016
Mouse
establishment of protein localization to organelle GO:0072594 118 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
negative regulation of sterol transport GO:0032372 4 0.016
regulation of secretion GO:0051046 274 0.016
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.016
intracellular protein transport GO:0006886 204 0.016
single organism nuclear import GO:1902593 95 0.016
cellular amide metabolic process GO:0043603 58 0.016
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.016
regulation of hemostasis GO:1900046 28 0.016
zymogen activation GO:0031638 41 0.016
Mouse
limb morphogenesis GO:0035108 149 0.016
anatomical structure homeostasis GO:0060249 145 0.016
epidermis development GO:0008544 187 0.016
stress activated protein kinase signaling cascade GO:0031098 81 0.016
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.016
transepithelial chloride transport GO:0030321 4 0.016
regulation of ras protein signal transduction GO:0046578 114 0.015
digestive system development GO:0055123 200 0.015
pinocytosis GO:0006907 6 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
renal system development GO:0072001 225 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
Mouse
regulation of mapk cascade GO:0043408 248 0.015
regulation of plasminogen activation GO:0010755 4 0.015
regulation of hormone secretion GO:0046883 88 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
camera type eye development GO:0043010 266 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
Mouse
cofactor metabolic process GO:0051186 80 0.015
pyruvate transport GO:0006848 2 0.015
fat cell differentiation GO:0045444 160 0.015
tissue homeostasis GO:0001894 115 0.015
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.015
Mouse
body fluid secretion GO:0007589 53 0.015
monosaccharide metabolic process GO:0005996 106 0.015
positive regulation of immune effector process GO:0002699 107 0.015
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
Mouse
dna metabolic process GO:0006259 303 0.014
positive regulation of phagocytosis GO:0050766 26 0.014
Mouse
response to alcohol GO:0097305 48 0.014
phagocytosis GO:0006909 66 0.014
Mouse
positive regulation of wound healing GO:0090303 17 0.014
gtp catabolic process GO:0006184 143 0.014
neuromuscular process GO:0050905 99 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
hemangioblast cell differentiation GO:0060217 1 0.014
cellularization GO:0007349 1 0.014
interleukin 10 secretion GO:0072608 4 0.014
vitamin d biosynthetic process GO:0042368 3 0.014
regionalization GO:0003002 337 0.014
hexose transport GO:0008645 56 0.014
membrane lipid metabolic process GO:0006643 53 0.014
nucleoside phosphate biosynthetic process GO:1901293 79 0.014
spermatogenesis GO:0007283 284 0.014
positive regulation of actin filament polymerization GO:0030838 26 0.014
digestive tract development GO:0048565 190 0.014
regulation of interleukin 8 secretion GO:2000482 2 0.014
negative regulation of leukocyte proliferation GO:0070664 46 0.014
sperm individualization GO:0007291 1 0.014
regulation of interleukin 1 alpha production GO:0032650 4 0.014
interspecies interaction between organisms GO:0044419 83 0.014
Mouse
alpha amino acid catabolic process GO:1901606 18 0.014
cytosolic calcium ion homeostasis GO:0051480 70 0.014
cognition GO:0050890 149 0.014
phenol containing compound metabolic process GO:0018958 60 0.014
b cell activation GO:0042113 161 0.013
lung development GO:0030324 164 0.013
feeding behavior GO:0007631 62 0.013
autophagy GO:0006914 45 0.013
negative regulation of inflammatory response GO:0050728 61 0.013
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.013
Mouse
regulation of peptide transport GO:0090087 91 0.013
protein oligomerization GO:0051259 67 0.013
organic acid catabolic process GO:0016054 51 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
kynurenine metabolic process GO:0070189 4 0.013
glycerolipid metabolic process GO:0046486 122 0.013
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
regulation of protein targeting GO:1903533 61 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
kidney development GO:0001822 213 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
response to water GO:0009415 1 0.013
locomotory behavior GO:0007626 195 0.013
atp catabolic process GO:0006200 55 0.013
positive regulation of interleukin 1 alpha production GO:0032730 4 0.013
icosanoid metabolic process GO:0006690 33 0.013
cellular response to prostaglandin stimulus GO:0071379 2 0.013
regulation of phagocytosis GO:0050764 33 0.013
Mouse
hexose transmembrane transport GO:0035428 7 0.013
renal system process GO:0003014 48 0.013
peptidyl lysine modification GO:0018205 77 0.013
bone development GO:0060348 120 0.012
adult behavior GO:0030534 135 0.012
response to lithium ion GO:0010226 10 0.012
skeletal system morphogenesis GO:0048705 203 0.012
circulatory system process GO:0003013 197 0.012
sequestering of calcium ion GO:0051208 18 0.012
regulation of interleukin 10 production GO:0032653 21 0.012
Mouse
cellular response to cadmium ion GO:0071276 3 0.012
regulation of fibrinolysis GO:0051917 1 0.012
cellular phosphate ion homeostasis GO:0030643 2 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
amino acid transmembrane transport GO:0003333 37 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
naphthalene containing compound metabolic process GO:0090420 1 0.012
protein catabolic process GO:0030163 221 0.012
telencephalon development GO:0021537 186 0.012
regulation of circadian rhythm GO:0042752 58 0.012
response to growth factor GO:0070848 198 0.012
vitamin metabolic process GO:0006766 23 0.012
calcium ion homeostasis GO:0055074 127 0.012
glucuronate metabolic process GO:0019585 2 0.012
protein glycosylation GO:0006486 55 0.012
cellular protein complex assembly GO:0043623 116 0.012
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
notch signaling pathway GO:0007219 71 0.012
Mouse
protein ubiquitination GO:0016567 171 0.012
Mouse
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.012
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.012
carbohydrate transport GO:0008643 62 0.012
fatty acid biosynthetic process GO:0006633 41 0.012
regulation of interferon beta production GO:0032648 13 0.012
protein acylation GO:0043543 64 0.012
regulation of defense response to bacterium GO:1900424 3 0.012
Mouse
response to hypoxia GO:0001666 58 0.012
positive regulation of cell development GO:0010720 237 0.012

Nlrp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.025
disease of anatomical entity DOID:7 0 0.025
eye and adnexa disease DOID:1492 0 0.025
nervous system disease DOID:863 0 0.025
eye disease DOID:5614 0 0.025
immune system disease DOID:2914 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
disease of metabolism DOID:0014667 0 0.022
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.016
acquired metabolic disease DOID:0060158 0 0.013
lipid metabolism disorder DOID:3146 0 0.012
inherited metabolic disorder DOID:655 0 0.012
steroid inherited metabolic disorder DOID:1701 0 0.012
physical disorder DOID:0080015 0 0.012