Mus musculus

231 known processes

Nos1

nitric oxide synthase 1, neuronal

(Aliases: NOS-I,NO,2310005C01Rik,bNOS,nNOS,Nos-1)

Nos1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 1.000
regulation of synaptic plasticity GO:0048167 87 0.999
Rat
response to peptide hormone GO:0043434 127 0.998
Rat
rhythmic process GO:0048511 174 0.997
Mouse
regulation of neurotransmitter uptake GO:0051580 6 0.996
calcium ion transport GO:0006816 159 0.995
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.995
regulation of feeding behavior GO:0060259 3 0.992
regulation of neurotransmitter transport GO:0051588 35 0.991
regulation of muscle system process GO:0090257 80 0.991
Mouse
morphogenesis of a branching structure GO:0001763 203 0.990
regulation of neurotransmitter levels GO:0001505 87 0.989
negative regulation of cell proliferation GO:0008285 296 0.988
Mouse Rat
smooth muscle contraction GO:0006939 44 0.987
long term synaptic potentiation GO:0060291 25 0.985
Rat
circadian rhythm GO:0007623 114 0.985
Mouse
response to ammonium ion GO:0060359 21 0.985
Rat
alpha amino acid metabolic process GO:1901605 59 0.984
Mouse Rat
feeding behavior GO:0007631 62 0.982
regulation of receptor activity GO:0010469 41 0.982
neuron neuron synaptic transmission GO:0007270 69 0.982
muscle system process GO:0003012 141 0.978
response to organic cyclic compound GO:0014070 198 0.977
Rat
response to decreased oxygen levels GO:0036293 59 0.976
Human Mouse Rat
neurotransmitter transport GO:0006836 76 0.975
muscle contraction GO:0006936 101 0.972
neuropeptide signaling pathway GO:0007218 19 0.966
response to oxygen levels GO:0070482 62 0.966
Human Mouse Rat
monocarboxylic acid metabolic process GO:0032787 191 0.964
response to inactivity GO:0014854 4 0.962
response to cocaine GO:0042220 14 0.959
Rat
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.955
cellular amino acid metabolic process GO:0006520 103 0.952
Mouse Rat
cytosolic calcium ion homeostasis GO:0051480 70 0.951
Rat
muscle adaptation GO:0043500 39 0.948
Mouse
cellular ketone metabolic process GO:0042180 84 0.948
cellular calcium ion homeostasis GO:0006874 119 0.947
Rat
endomembrane system organization GO:0010256 147 0.947
regulation of kinase activity GO:0043549 249 0.944
regulation of circadian sleep wake cycle GO:0042749 3 0.940
axonogenesis GO:0007409 274 0.940
Zebrafish
heart contraction GO:0060047 93 0.939
regulation of the force of heart contraction GO:0002026 17 0.938
response to food GO:0032094 17 0.935
regulation of apoptotic signaling pathway GO:2001233 197 0.935
regulation of catecholamine secretion GO:0050433 12 0.934
regulation of fatty acid metabolic process GO:0019217 28 0.933
circadian sleep wake cycle GO:0042745 5 0.933
nitric oxide biosynthetic process GO:0006809 25 0.929
regulation of ion transport GO:0043269 215 0.927
cellular response to organonitrogen compound GO:0071417 145 0.926
Rat
positive regulation of map kinase activity GO:0043406 84 0.924
regulation of insulin receptor signaling pathway GO:0046626 21 0.923
ovulation GO:0030728 15 0.922
Mouse
divalent metal ion transport GO:0070838 172 0.920
cellular response to peptide GO:1901653 92 0.919
peptidyl cysteine modification GO:0018198 8 0.916
neuron death GO:0070997 154 0.916
Rat
organonitrogen compound biosynthetic process GO:1901566 192 0.909
regulation of protein serine threonine kinase activity GO:0071900 157 0.906
glucose homeostasis GO:0042593 128 0.905
response to extracellular stimulus GO:0009991 127 0.904
Rat
response to corticosteroid GO:0031960 20 0.903
positive regulation of mapk cascade GO:0043410 170 0.902
regulation of membrane potential GO:0042391 192 0.901
regulation of cellular amine metabolic process GO:0033238 20 0.899
sensory perception of pain GO:0019233 47 0.898
Rat
amine metabolic process GO:0009308 45 0.895
response to lipopolysaccharide GO:0032496 128 0.892
Mouse Rat
regulation of the force of heart contraction by chemical signal GO:0003057 5 0.889
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.888
multicellular organismal response to stress GO:0033555 62 0.886
Human
response to drug GO:0042493 75 0.885
cellular divalent inorganic cation homeostasis GO:0072503 127 0.883
Rat
multi multicellular organism process GO:0044706 109 0.881
Rat
heart process GO:0003015 94 0.880
regulation of map kinase activity GO:0043405 120 0.876
regulation of circadian rhythm GO:0042752 58 0.876
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.876
circulatory system process GO:0003013 197 0.873
regulation of secretion GO:0051046 274 0.872
Rat
regulation of reproductive process GO:2000241 66 0.870
response to alkaloid GO:0043279 34 0.868
Rat
response to amphetamine GO:0001975 16 0.866
negative regulation of cellular protein metabolic process GO:0032269 247 0.866
Rat
regulation of glucose metabolic process GO:0010906 60 0.866
sensory perception GO:0007600 245 0.866
Rat
regulation of transferase activity GO:0051338 263 0.865
positive regulation of blood circulation GO:1903524 22 0.865
Human Rat
response to dexamethasone GO:0071548 8 0.864
divalent inorganic cation transport GO:0072511 178 0.863
glutamine family amino acid metabolic process GO:0009064 15 0.858
Mouse Rat
regulation of protein kinase activity GO:0045859 232 0.855
response to inorganic substance GO:0010035 96 0.854
Rat
response to alcohol GO:0097305 48 0.850
Rat
mapk cascade GO:0000165 281 0.850
regulation of secretion by cell GO:1903530 249 0.849
Rat
carboxylic acid catabolic process GO:0046395 51 0.849
Mouse Rat
g protein coupled receptor signaling pathway involved in heart process GO:0086103 4 0.847
glucose metabolic process GO:0006006 92 0.842
regulation of cell projection organization GO:0031344 206 0.842
negative regulation of serotonin uptake GO:0051612 2 0.842
negative regulation of potassium ion transport GO:0043267 7 0.841
regulation of ion transmembrane transport GO:0034765 119 0.840
Rat
membrane organization GO:0061024 245 0.839
response to steroid hormone GO:0048545 56 0.839
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.836
positive regulation of glial cell proliferation GO:0060252 4 0.834
adrenergic receptor signaling pathway involved in heart process GO:0086023 3 0.832
memory GO:0007613 58 0.831
cognition GO:0050890 149 0.830
hexose metabolic process GO:0019318 98 0.823
peptidyl cysteine s nitrosylation GO:0018119 4 0.820
positive regulation of fatty acid oxidation GO:0046321 4 0.819
peptidyl serine phosphorylation GO:0018105 74 0.819
Rat
positive regulation of protein modification process GO:0031401 299 0.816
regulation of multi organism process GO:0043900 111 0.815
blood circulation GO:0008015 195 0.815
regulation of calcium ion transport GO:0051924 69 0.812
regulation of nucleotide metabolic process GO:0006140 169 0.809
positive regulation of ion transport GO:0043270 65 0.809
Rat
hormone metabolic process GO:0042445 86 0.805
positive regulation of kinase activity GO:0033674 155 0.800
carbohydrate metabolic process GO:0005975 230 0.798
myotube differentiation GO:0014902 105 0.798
action potential GO:0001508 78 0.797
apoptotic signaling pathway GO:0097190 306 0.793
regulation of tube size GO:0035150 57 0.789
Human Mouse Rat
learning or memory GO:0007611 148 0.788
nitric oxide metabolic process GO:0046209 25 0.786
arginine catabolic process GO:0006527 2 0.786
Mouse Rat
regulation of inflammatory response GO:0050727 147 0.784
negative regulation of apoptotic signaling pathway GO:2001234 104 0.779
cellular amine metabolic process GO:0044106 44 0.778
negative regulation of phosphate metabolic process GO:0045936 184 0.771
Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.771
body fluid secretion GO:0007589 53 0.767
regulation of carbohydrate metabolic process GO:0006109 75 0.766
response to temperature stimulus GO:0009266 55 0.764
Human Rat
peptidyl serine modification GO:0018209 83 0.762
Rat
negative regulation of molecular function GO:0044092 258 0.755
organonitrogen compound catabolic process GO:1901565 264 0.750
Mouse Rat
organic acid catabolic process GO:0016054 51 0.749
Mouse Rat
response to glucocorticoid GO:0051384 20 0.749
negative regulation of behavior GO:0048521 14 0.748
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.748
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.747
organic hydroxy compound transport GO:0015850 93 0.743
response to monosaccharide GO:0034284 67 0.742
ammonia assimilation cycle GO:0019676 2 0.741
locomotory behavior GO:0007626 195 0.738
muscle cell cellular homeostasis GO:0046716 12 0.736
regulation of response to food GO:0032095 10 0.734
regulation of androgen receptor signaling pathway GO:0060765 3 0.731
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.728
synaptic transmission gabaergic GO:0051932 19 0.725
response to pain GO:0048265 26 0.724
development of primary sexual characteristics GO:0045137 143 0.723
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.723
Mouse
response to growth factor GO:0070848 198 0.723
g protein coupled receptor signaling pathway GO:0007186 243 0.722
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.722
regulation of gluconeogenesis GO:0006111 30 0.718
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.715
response to molecule of bacterial origin GO:0002237 143 0.714
Mouse Rat
glutamate receptor signaling pathway GO:0007215 35 0.711
neuron apoptotic process GO:0051402 142 0.708
regulation of blood vessel size GO:0050880 56 0.707
Human Mouse Rat
visual learning GO:0008542 44 0.707
regulation of ion transmembrane transporter activity GO:0032412 54 0.707
response to organonitrogen compound GO:0010243 246 0.702
Rat
camp metabolic process GO:0046058 40 0.701
response to activity GO:0014823 13 0.700
Rat
regulation of cellular catabolic process GO:0031329 242 0.700
mating GO:0007618 27 0.697
negative regulation of muscle contraction GO:0045932 12 0.691
eating behavior GO:0042755 15 0.690
cellular response to biotic stimulus GO:0071216 92 0.688
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.687
female gonad development GO:0008585 71 0.686
Mouse
branching involved in salivary gland morphogenesis GO:0060445 26 0.681
catecholamine metabolic process GO:0006584 30 0.680
hair cycle phase GO:0044851 16 0.680
regulation of hormone levels GO:0010817 211 0.677
Rat
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.671
protein kinase b signaling GO:0043491 74 0.669
regulation of nucleoside metabolic process GO:0009118 130 0.665
learning GO:0007612 98 0.660
lactation GO:0007595 25 0.660
cellular response to insulin stimulus GO:0032869 78 0.660
regulation of synapse structural plasticity GO:0051823 4 0.658
digestion GO:0007586 40 0.657
muscle cell differentiation GO:0042692 261 0.656
regulation of protein kinase b signaling GO:0051896 56 0.653
regulation of blood circulation GO:1903522 93 0.653
nitrogen compound transport GO:0071705 271 0.653
response to hypoxia GO:0001666 58 0.652
Human Mouse Rat
protein oligomerization GO:0051259 67 0.650
regulation of nitrogen cycle metabolic process GO:1903314 1 0.650
oxidation reduction process GO:0055114 342 0.649
cation transport GO:0006812 399 0.645
cell adhesion GO:0007155 329 0.645
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.640
regulation of serotonin uptake GO:0051611 2 0.640
regulation of defense response GO:0031347 233 0.639
negative regulation of muscle adaptation GO:0014745 2 0.639
Mouse
regulation of morphogenesis of a branching structure GO:0060688 53 0.635
regulation of peptidyl serine phosphorylation GO:0033135 39 0.632
Rat
regulation of transporter activity GO:0032409 57 0.629
positive regulation of transferase activity GO:0051347 167 0.627
monosaccharide metabolic process GO:0005996 106 0.626
regulation of lymphocyte proliferation GO:0050670 117 0.625
activation of mapk activity GO:0000187 59 0.625
negative regulation of phosphorylation GO:0042326 166 0.617
Rat
amine transport GO:0015837 21 0.616
negative regulation of protein metabolic process GO:0051248 282 0.613
Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.612
regulation of neuron projection development GO:0010975 169 0.612
vascular process in circulatory system GO:0003018 62 0.611
Human Mouse Rat
regulation of fatty acid oxidation GO:0046320 10 0.611
calcium ion transmembrane transport GO:0070588 85 0.610
muscle cell development GO:0055001 133 0.607
cellular response to peptide hormone stimulus GO:0071375 92 0.606
positive regulation of apoptotic signaling pathway GO:2001235 95 0.606
cgmp mediated signaling GO:0019934 3 0.602
inorganic cation transmembrane transport GO:0098662 207 0.601
Rat
second messenger mediated signaling GO:0019932 73 0.587
Zebrafish Rat
cellular response to lipid GO:0071396 145 0.586
Mouse
reproductive behavior GO:0019098 32 0.584
regulation of carbohydrate biosynthetic process GO:0043255 40 0.582
kidney epithelium development GO:0072073 121 0.579
anion transport GO:0006820 177 0.576
lipid catabolic process GO:0016042 69 0.576
glucose import GO:0046323 32 0.572
skeletal muscle fiber development GO:0048741 58 0.571
muscle tissue development GO:0060537 308 0.568
protein catabolic process GO:0030163 221 0.567
Mouse
regulation of ovulation GO:0060278 3 0.565
associative learning GO:0008306 61 0.564
regulation of mapk cascade GO:0043408 248 0.559
carbohydrate derivative biosynthetic process GO:1901137 183 0.559
negative regulation of secretion GO:0051048 61 0.555
Rat
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.551
sleep GO:0030431 7 0.548
calcium ion homeostasis GO:0055074 127 0.546
Rat
regulation of cellular amino acid metabolic process GO:0006521 5 0.546
negative regulation of synaptic transmission glutamatergic GO:0051967 4 0.545
cyclic nucleotide metabolic process GO:0009187 59 0.544
striated muscle contraction GO:0006941 45 0.544
neuron migration GO:0001764 122 0.540
regulation of nitric oxide synthase activity GO:0050999 6 0.539
nucleotide biosynthetic process GO:0009165 78 0.535
negative regulation of feeding behavior GO:2000252 1 0.534
intestinal cholesterol absorption GO:0030299 5 0.533
acylglycerol homeostasis GO:0055090 16 0.533
regulation of purine nucleotide metabolic process GO:1900542 169 0.532
synaptic transmission glutamatergic GO:0035249 36 0.531
regulation of leukocyte proliferation GO:0070663 121 0.531
dopamine secretion GO:0014046 9 0.530
ovulation from ovarian follicle GO:0001542 9 0.530
Mouse
cellular response to acid chemical GO:0071229 68 0.520
regulation of camp metabolic process GO:0030814 30 0.520
extrinsic apoptotic signaling pathway GO:0097191 126 0.519
response to light stimulus GO:0009416 135 0.517
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger GO:0007199 1 0.517
catecholamine secretion GO:0050432 15 0.515
positive regulation of dendrite development GO:1900006 21 0.514
regulation of nitric oxide biosynthetic process GO:0045428 18 0.513
multi organism reproductive behavior GO:0044705 29 0.513
ribonucleotide biosynthetic process GO:0009260 59 0.512
striated muscle cell development GO:0055002 125 0.512
negative regulation of intracellular signal transduction GO:1902532 167 0.512
cellular response to growth factor stimulus GO:0071363 197 0.512
regulation of organelle organization GO:0033043 289 0.511
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.510
arginine metabolic process GO:0006525 2 0.510
Mouse Rat
peptidyl amino acid modification GO:0018193 336 0.509
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.508
response to morphine GO:0043278 9 0.507
nucleoside phosphate biosynthetic process GO:1901293 79 0.507
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.506
placenta development GO:0001890 140 0.503
glycosyl compound metabolic process GO:1901657 246 0.503
positive regulation of adrenergic receptor signaling pathway GO:0071879 3 0.502
regulation of system process GO:0044057 200 0.501
purine ribonucleotide metabolic process GO:0009150 290 0.499
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.498
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.495
response to corticosterone GO:0051412 1 0.493
regulation of synaptic transmission gabaergic GO:0032228 17 0.491
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.485
response to nutrient levels GO:0031667 109 0.484
Rat
response to tumor necrosis factor GO:0034612 26 0.482
multicellular organism growth GO:0035264 161 0.479
habituation GO:0046959 3 0.478
establishment of blood nerve barrier GO:0008065 3 0.478
monocarboxylic acid catabolic process GO:0072329 27 0.474
response to ketone GO:1901654 15 0.469
positive regulation of nervous system development GO:0051962 221 0.465
maternal process involved in female pregnancy GO:0060135 32 0.464
ion transmembrane transport GO:0034220 361 0.463
Rat
response to oxidative stress GO:0006979 123 0.460
Rat
positive regulation of programmed cell death GO:0043068 218 0.459
urogenital system development GO:0001655 261 0.459
negative regulation of ion transport GO:0043271 28 0.457
acetylcholine transport GO:0015870 2 0.457
cyclic purine nucleotide metabolic process GO:0052652 43 0.457
hormone secretion GO:0046879 128 0.455
Rat
regulation of cell adhesion GO:0030155 154 0.455
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.451
regulation of heart contraction GO:0008016 77 0.450
neurotransmitter secretion GO:0007269 62 0.450
carbohydrate homeostasis GO:0033500 128 0.449
regulation of monooxygenase activity GO:0032768 7 0.448
positive regulation of cell migration GO:0030335 109 0.447
embryonic placenta development GO:0001892 98 0.447
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.446
purine containing compound biosynthetic process GO:0072522 70 0.446
circadian regulation of gene expression GO:0032922 48 0.444
neurotransmitter uptake GO:0001504 14 0.443
smooth muscle cell migration GO:0014909 10 0.442
negative regulation of secretion by cell GO:1903531 54 0.441
Rat
regulation of smooth muscle contraction GO:0006940 22 0.440
cellular response to inorganic substance GO:0071241 37 0.439
sensory perception of chemical stimulus GO:0007606 51 0.435
cellular response to extracellular stimulus GO:0031668 81 0.434
organic acid transport GO:0015849 101 0.433
regulation of hydrolase activity GO:0051336 246 0.433
organelle localization GO:0051640 179 0.431
circadian behavior GO:0048512 13 0.429
morphogenesis of a branching epithelium GO:0061138 193 0.428
regulation of metal ion transport GO:0010959 106 0.427
purine nucleoside metabolic process GO:0042278 241 0.427
carboxylic acid transport GO:0046942 100 0.427
reactive oxygen species metabolic process GO:0072593 84 0.426
Mouse
small molecule catabolic process GO:0044282 71 0.423
Mouse Rat
ureteric bud development GO:0001657 94 0.422
peptide transport GO:0015833 133 0.421
Rat
response to peptide GO:1901652 136 0.417
Rat
regulation of hormone secretion GO:0046883 88 0.417
Rat
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.413
positive regulation of smooth muscle cell migration GO:0014911 4 0.412
renal system process GO:0003014 48 0.411
ribose phosphate biosynthetic process GO:0046390 59 0.404
fatty acid metabolic process GO:0006631 121 0.403
regulation of coagulation GO:0050818 31 0.403
myelination in peripheral nervous system GO:0022011 19 0.401
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.401
regulation of response to wounding GO:1903034 189 0.400
regulation of synaptic transmission glutamatergic GO:0051966 19 0.398
regulation of dopamine uptake involved in synaptic transmission GO:0051584 2 0.397
positive regulation of growth GO:0045927 104 0.395
intestinal absorption GO:0050892 13 0.392
regulation of neuron differentiation GO:0045664 281 0.391
hepaticobiliary system development GO:0061008 67 0.390
Zebrafish
photoreceptor cell differentiation GO:0046530 52 0.390
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.389
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.386
directional locomotion GO:0033058 3 0.385
cellular metal ion homeostasis GO:0006875 151 0.384
Rat
ensheathment of neurons GO:0007272 76 0.383
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.383
insulin receptor signaling pathway GO:0008286 49 0.383
cellular carbohydrate metabolic process GO:0044262 119 0.381
cellular protein catabolic process GO:0044257 155 0.379
plasma membrane repair GO:0001778 7 0.379
regulation of glycogen metabolic process GO:0070873 13 0.379
response to reactive oxygen species GO:0000302 56 0.379
Rat
dendritic spine morphogenesis GO:0060997 22 0.376
regulation of neuron death GO:1901214 134 0.376
Rat
cation transmembrane transport GO:0098655 266 0.372
Rat
positive regulation of protein kinase activity GO:0045860 144 0.372
negative regulation of neurotransmitter transport GO:0051589 7 0.369
heterocycle catabolic process GO:0046700 280 0.367
positive regulation of cellular amine metabolic process GO:0033240 5 0.366
divalent inorganic cation homeostasis GO:0072507 138 0.366
Rat
exocrine system development GO:0035272 45 0.365
regulation of steroid biosynthetic process GO:0050810 26 0.364
negative regulation of protein processing GO:0010955 79 0.364
regulation of cell activation GO:0050865 289 0.364
potassium ion transport GO:0006813 52 0.363
ovulation cycle GO:0042698 59 0.361
Mouse
regulation of cell motility GO:2000145 236 0.361
response to amino acid GO:0043200 37 0.361
lipid modification GO:0030258 65 0.360
negative regulation of hydrolase activity GO:0051346 71 0.358
regulation of blood pressure GO:0008217 93 0.357
Rat
serotonin transport GO:0006837 11 0.356
negative regulation of blood pressure GO:0045776 22 0.356
Rat
coagulation GO:0050817 78 0.355
nucleoside monophosphate metabolic process GO:0009123 85 0.353
nucleotide metabolic process GO:0009117 332 0.349
cell proliferation in hindbrain GO:0021534 10 0.348
purine containing compound metabolic process GO:0072521 311 0.347
nucleoside triphosphate metabolic process GO:0009141 230 0.347
negative regulation of mapk cascade GO:0043409 65 0.344
nucleoside phosphate metabolic process GO:0006753 338 0.343
regulation of neuronal synaptic plasticity GO:0048168 30 0.343
female gamete generation GO:0007292 74 0.342
Mouse
regulation of renal output by angiotensin GO:0002019 2 0.342
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.340
cellular chemical homeostasis GO:0055082 215 0.340
Rat
cellular response to organic cyclic compound GO:0071407 87 0.340
Rat
cellular response to hormone stimulus GO:0032870 150 0.339
establishment of protein localization to membrane GO:0090150 54 0.338
positive regulation of neuron differentiation GO:0045666 141 0.337
response to testosterone GO:0033574 3 0.336
leukocyte mediated immunity GO:0002443 174 0.334
neuron projection extension GO:1990138 64 0.334
fatty acid catabolic process GO:0009062 25 0.333
positive regulation of leukocyte proliferation GO:0070665 73 0.332
response to hyperoxia GO:0055093 2 0.330
cardiocyte differentiation GO:0035051 87 0.330
response to insulin GO:0032868 100 0.329
negative regulation of endopeptidase activity GO:0010951 44 0.327
positive regulation of vasoconstriction GO:0045907 4 0.326
cardiac muscle tissue development GO:0048738 130 0.324
negative regulation of protein kinase b signaling GO:0051898 18 0.321
response to amine GO:0014075 16 0.320
fatty acid beta oxidation GO:0006635 16 0.319
ribose phosphate metabolic process GO:0019693 291 0.319
gonad development GO:0008406 141 0.317
Mouse
acylglycerol metabolic process GO:0006639 55 0.315
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.314
regulation of cation channel activity GO:2001257 22 0.314
regulation of muscle adaptation GO:0043502 31 0.313
Mouse
epithelial tube morphogenesis GO:0060562 303 0.312
regulation of monocyte extravasation GO:2000437 2 0.312
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.312
small gtpase mediated signal transduction GO:0007264 97 0.311
energy reserve metabolic process GO:0006112 39 0.311
temperature homeostasis GO:0001659 26 0.309
positive regulation of carbohydrate metabolic process GO:0045913 30 0.307
energy derivation by oxidation of organic compounds GO:0015980 77 0.306
cellular homeostasis GO:0019725 240 0.306
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.304
negative regulation of proteolysis GO:0045861 74 0.304
regulation of intracellular transport GO:0032386 159 0.302
nucleocytoplasmic transport GO:0006913 139 0.302
camera type eye development GO:0043010 266 0.301
chemotaxis GO:0006935 247 0.299
regulation of cytoplasmic transport GO:1903649 112 0.298
positive regulation of cell death GO:0010942 224 0.298
Rat
cholesterol esterification GO:0034435 3 0.293
cellular glucose homeostasis GO:0001678 52 0.292
negative regulation of phosphorus metabolic process GO:0010563 184 0.290
Rat
mammary gland branching involved in pregnancy GO:0060745 6 0.287
protein localization to membrane GO:0072657 108 0.287
cellular response to glucocorticoid stimulus GO:0071385 13 0.285
response to heat GO:0009408 27 0.285
Human Rat
response to starvation GO:0042594 65 0.284
regulation of cell migration GO:0030334 219 0.284
acetate ester transport GO:1901374 2 0.283
regulation of neuron apoptotic process GO:0043523 122 0.283
negative regulation of response to wounding GO:1903035 77 0.282
mammary gland lobule development GO:0061377 22 0.281
anatomical structure homeostasis GO:0060249 145 0.281
nucleoside metabolic process GO:0009116 246 0.280
protein nitrosylation GO:0017014 4 0.280
immune effector process GO:0002252 321 0.279
telencephalon development GO:0021537 186 0.278
purine nucleotide biosynthetic process GO:0006164 65 0.278
forebrain development GO:0030900 302 0.277
ribonucleotide metabolic process GO:0009259 291 0.277
mitochondrion organization GO:0007005 134 0.276
ras protein signal transduction GO:0007265 77 0.273
regulation of corticosterone secretion GO:2000852 2 0.270
skeletal muscle organ development GO:0060538 163 0.265
brown fat cell differentiation GO:0050873 36 0.263
intracellular receptor signaling pathway GO:0030522 74 0.261
cellular response to dexamethasone stimulus GO:0071549 8 0.261
striated muscle tissue development GO:0014706 293 0.259
heart trabecula formation GO:0060347 14 0.259
positive regulation of dendritic spine development GO:0060999 12 0.259
glutamate metabolic process GO:0006536 9 0.259
lipid oxidation GO:0034440 29 0.257
cardiac muscle cell development GO:0055013 39 0.257
regulation of catecholamine uptake involved in synaptic transmission GO:0051940 2 0.257
glutamine family amino acid catabolic process GO:0009065 5 0.255
Mouse Rat
positive regulation of protein phosphorylation GO:0001934 242 0.255
steroid metabolic process GO:0008202 119 0.254
male gamete generation GO:0048232 285 0.252
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.251
gliogenesis GO:0042063 141 0.251
hindbrain development GO:0030902 128 0.249
response to vitamin d GO:0033280 3 0.249
regulation of appetite GO:0032098 12 0.249
organic anion transport GO:0015711 137 0.248
cell growth GO:0016049 130 0.248
Zebrafish
cell migration involved in metanephros development GO:0035788 2 0.247

Nos1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.638
nervous system disease DOID:863 0 0.638
central nervous system disease DOID:331 0 0.514
disease of metabolism DOID:0014667 0 0.394
diabetes mellitus DOID:9351 0 0.307
type 2 diabetes mellitus DOID:9352 0 0.307
carbohydrate metabolism disease DOID:0050013 0 0.307
glucose metabolism disease DOID:4194 0 0.307
acquired metabolic disease DOID:0060158 0 0.307