Mus musculus

0 known processes

Nphs2

nephrosis 2 homolog, podocin (human)

(Aliases: SRN1,AI790225,PDCN)

Nphs2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pronephric nephron development GO:0039019 1 0.980
Zebrafish
renal system process GO:0003014 48 0.841
kidney development GO:0001822 213 0.776
Zebrafish
glomerular basement membrane development GO:0032836 8 0.743
transmembrane transport GO:0055085 412 0.680
Mouse
urogenital system development GO:0001655 261 0.651
Zebrafish
glomerulus development GO:0032835 40 0.644
Zebrafish
renal filtration cell differentiation GO:0061318 10 0.624
renal system development GO:0072001 225 0.581
Zebrafish
regulation of peptidase activity GO:0052547 96 0.569
glomerular epithelial cell development GO:0072310 6 0.557
inter male aggressive behavior GO:0002121 3 0.551
purine nucleoside triphosphate metabolic process GO:0009144 226 0.549
spermatogenesis GO:0007283 284 0.512
glycosyl compound metabolic process GO:1901657 246 0.484
regulation of anatomical structure size GO:0090066 178 0.483
ion transmembrane transport GO:0034220 361 0.481
Mouse
actin cytoskeleton organization GO:0030036 220 0.481
myotube differentiation GO:0014902 105 0.475
organic cyclic compound catabolic process GO:1901361 295 0.473
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.467
purine nucleoside catabolic process GO:0006152 205 0.441
cell adhesion GO:0007155 329 0.434
syncytium formation by plasma membrane fusion GO:0000768 42 0.426
cell cell adhesion GO:0098609 41 0.400
extracellular structure organization GO:0043062 148 0.396
ribonucleotide catabolic process GO:0009261 208 0.392
nucleoside metabolic process GO:0009116 246 0.387
nucleoside catabolic process GO:0009164 206 0.372
organic acid transport GO:0015849 101 0.365
purine ribonucleoside catabolic process GO:0046130 205 0.364
regulation of endocytic recycling GO:2001135 3 0.364
carnitine transmembrane transport GO:1902603 3 0.361
purine nucleotide catabolic process GO:0006195 211 0.359
regulation of ion transport GO:0043269 215 0.354
Mouse
glomerular visceral epithelial cell development GO:0072015 6 0.347
anion transport GO:0006820 177 0.344
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.332
glycosyl compound catabolic process GO:1901658 206 0.331
purine nucleoside metabolic process GO:0042278 241 0.322
cellular amino acid metabolic process GO:0006520 103 0.321
purine nucleoside triphosphate catabolic process GO:0009146 203 0.321
positive regulation of endopeptidase activity GO:0010950 43 0.306
release of cytochrome c from mitochondria GO:0001836 23 0.303
negative regulation of phosphorylation GO:0042326 166 0.302
extracellular matrix organization GO:0030198 147 0.301
male gamete generation GO:0048232 285 0.298
purine containing compound metabolic process GO:0072521 311 0.297
positive regulation of proteolysis GO:0045862 85 0.293
cation transport GO:0006812 399 0.291
Mouse
positive regulation of nervous system development GO:0051962 221 0.289
digestive tract development GO:0048565 190 0.282
amine metabolic process GO:0009308 45 0.281
glial cell apoptotic process GO:0034349 3 0.277
carnitine transport GO:0015879 3 0.276
response to peptide hormone GO:0043434 127 0.276
muscle cell differentiation GO:0042692 261 0.273
organonitrogen compound catabolic process GO:1901565 264 0.271
spermatid differentiation GO:0048515 115 0.270
ribose phosphate metabolic process GO:0019693 291 0.268
nucleoside phosphate metabolic process GO:0006753 338 0.265
monosaccharide metabolic process GO:0005996 106 0.256
nucleobase containing small molecule metabolic process GO:0055086 352 0.255
positive regulation of cholesterol storage GO:0010886 3 0.246
glomerular epithelium development GO:0072010 11 0.244
multicellular organismal signaling GO:0035637 91 0.239
muscle cell development GO:0055001 133 0.239
germ cell development GO:0007281 185 0.235
amino acid transmembrane transport GO:0003333 37 0.234
heterocycle catabolic process GO:0046700 280 0.232
nucleotide metabolic process GO:0009117 332 0.231
purine nucleotide metabolic process GO:0006163 302 0.231
atp metabolic process GO:0046034 75 0.231
nucleoside triphosphate metabolic process GO:0009141 230 0.231
skeletal muscle organ development GO:0060538 163 0.229
nephron development GO:0072006 109 0.229
Zebrafish
organic anion transport GO:0015711 137 0.228
neuron apoptotic process GO:0051402 142 0.227
response to growth factor GO:0070848 198 0.226
spermatid development GO:0007286 108 0.222
endocytosis GO:0006897 168 0.209
regulation of membrane potential GO:0042391 192 0.206
negative regulation of response to wounding GO:1903035 77 0.203
single organism cell adhesion GO:0098602 156 0.201
ribonucleotide metabolic process GO:0009259 291 0.197
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.194
epithelial tube morphogenesis GO:0060562 303 0.192
purine containing compound catabolic process GO:0072523 213 0.190
intracellular protein transport GO:0006886 204 0.188
neuronal action potential GO:0019228 54 0.187
epithelial cell differentiation involved in kidney development GO:0035850 23 0.186
nucleotide catabolic process GO:0009166 217 0.186
ribonucleoside triphosphate catabolic process GO:0009203 199 0.185
plasma lipoprotein particle clearance GO:0034381 13 0.184
regulation of actin cytoskeleton organization GO:0032956 84 0.184
purine ribonucleotide catabolic process GO:0009154 208 0.183
apoptotic signaling pathway GO:0097190 306 0.182
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.181
ribonucleoside monophosphate catabolic process GO:0009158 57 0.180
purine ribonucleotide metabolic process GO:0009150 290 0.179
regulation of proteolysis GO:0030162 164 0.179
cell junction organization GO:0034330 77 0.177
single organismal cell cell adhesion GO:0016337 131 0.176
defense response to other organism GO:0098542 197 0.176
positive regulation of hydrolase activity GO:0051345 148 0.175
nucleoside monophosphate metabolic process GO:0009123 85 0.174
nucleoside phosphate catabolic process GO:1901292 222 0.174
maternal process involved in female pregnancy GO:0060135 32 0.172
cellular nitrogen compound catabolic process GO:0044270 280 0.167
glomerular epithelial cell differentiation GO:0072311 10 0.166
carboxylic acid transport GO:0046942 100 0.165
response to organonitrogen compound GO:0010243 246 0.164
atp catabolic process GO:0006200 55 0.161
regulation of actin filament based process GO:0032970 99 0.159
oxidation reduction process GO:0055114 342 0.156
purine nucleoside monophosphate catabolic process GO:0009128 58 0.155
response to peptide GO:1901652 136 0.152
negative regulation of cell adhesion GO:0007162 45 0.148
establishment of protein localization to plasma membrane GO:0090002 34 0.148
regulation of hydrolase activity GO:0051336 246 0.148
regulation of cellular amine metabolic process GO:0033238 20 0.148
forebrain development GO:0030900 302 0.147
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.146
regulation of cell adhesion GO:0030155 154 0.146
locomotory behavior GO:0007626 195 0.145
regulation of cellular component size GO:0032535 121 0.143
positive regulation of glial cell proliferation GO:0060252 4 0.142
interleukin 10 secretion GO:0072608 4 0.142
purine ribonucleoside metabolic process GO:0046128 241 0.142
regulation of plasma lipoprotein particle levels GO:0097006 23 0.141
lipid homeostasis GO:0055088 63 0.140
aromatic compound catabolic process GO:0019439 286 0.140
transmission of nerve impulse GO:0019226 76 0.138
regulation of defense response GO:0031347 233 0.137
cellular response to insulin stimulus GO:0032869 78 0.137
action potential GO:0001508 78 0.136
positive regulation of endocytic recycling GO:2001137 2 0.134
carbohydrate derivative catabolic process GO:1901136 231 0.133
regulation of actin filament length GO:0030832 45 0.132
positive regulation of myotube differentiation GO:0010831 24 0.131
cellular protein complex assembly GO:0043623 116 0.131
digestive tract morphogenesis GO:0048546 147 0.131
dna metabolic process GO:0006259 303 0.130
urate transport GO:0015747 1 0.129
ossification GO:0001503 216 0.128
response to nutrient levels GO:0031667 109 0.128
regulation of cell activation GO:0050865 289 0.128
cell cell junction organization GO:0045216 72 0.128
ribonucleoside metabolic process GO:0009119 245 0.127
ribonucleoside triphosphate metabolic process GO:0009199 220 0.125
protein maturation GO:0051604 176 0.124
epithelial cell development GO:0002064 159 0.124
carbohydrate transport GO:0008643 62 0.122
positive regulation of neuron differentiation GO:0045666 141 0.120
syncytium formation GO:0006949 43 0.118
positive regulation of cell projection organization GO:0031346 95 0.117
cellular amine metabolic process GO:0044106 44 0.117
ribonucleoside catabolic process GO:0042454 206 0.115
actin filament polymerization GO:0030041 44 0.115
positive regulation of cell development GO:0010720 237 0.115
glomerulus morphogenesis GO:0072102 10 0.114
axon ensheathment GO:0008366 76 0.114
amino acid transport GO:0006865 61 0.113
positive regulation of protein modification process GO:0031401 299 0.113
regulation of actin filament polymerization GO:0030833 38 0.112
protein polymerization GO:0051258 57 0.112
actin filament organization GO:0007015 113 0.109
mesoderm development GO:0007498 100 0.107
mesonephric tubule development GO:0072164 94 0.107
formation of radial glial scaffolds GO:0021943 4 0.106
sterol homeostasis GO:0055092 45 0.106
anion transmembrane transport GO:0098656 71 0.104
regulation of cellular amino acid metabolic process GO:0006521 5 0.103
embryonic epithelial tube formation GO:0001838 130 0.103
regulation of cellular component biogenesis GO:0044087 181 0.103
motor neuron migration GO:0097475 4 0.103
regulation of protein complex assembly GO:0043254 83 0.102
regulation of cytoskeleton organization GO:0051493 122 0.102
peptidyl amino acid modification GO:0018193 336 0.102
cellular response to organonitrogen compound GO:0071417 145 0.102
post embryonic organ development GO:0048569 17 0.101
defense response to virus GO:0051607 68 0.101
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.101
carboxylic acid biosynthetic process GO:0046394 86 0.100
nitrogen compound transport GO:0071705 271 0.100
digestion GO:0007586 40 0.099
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.099
carbohydrate metabolic process GO:0005975 230 0.098
negative regulation of cell proliferation GO:0008285 296 0.098
negative regulation of protein phosphorylation GO:0001933 126 0.098
response to insulin GO:0032868 100 0.098
meiotic nuclear division GO:0007126 115 0.096
positive regulation of cellular amine metabolic process GO:0033240 5 0.095
cellular ketone metabolic process GO:0042180 84 0.094
immune effector process GO:0002252 321 0.094
mitochondrion organization GO:0007005 134 0.093
muscle tissue development GO:0060537 308 0.093
cellular response to gamma radiation GO:0071480 4 0.092
regulation of lymphocyte proliferation GO:0050670 117 0.091
negative regulation of protein metabolic process GO:0051248 282 0.090
organophosphate catabolic process GO:0046434 232 0.090
regulation of organelle organization GO:0033043 289 0.089
positive regulation of actin filament polymerization GO:0030838 26 0.088
neurotransmitter transport GO:0006836 76 0.088
ureteric bud development GO:0001657 94 0.088
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.085
deoxyribonucleotide biosynthetic process GO:0009263 6 0.085
mesodermal cell migration GO:0008078 4 0.085
negative regulation of hydrolase activity GO:0051346 71 0.084
mesangial cell differentiation GO:0072007 4 0.084
renal filtration GO:0097205 7 0.083
regulation of neuron differentiation GO:0045664 281 0.083
regulation of lymphocyte differentiation GO:0045619 107 0.083
response to vitamin d GO:0033280 3 0.083
visual perception GO:0007601 52 0.082
nephron epithelium development GO:0072009 92 0.082
regulation of myeloid dendritic cell activation GO:0030885 5 0.082
monosaccharide transport GO:0015749 58 0.082
stress activated mapk cascade GO:0051403 80 0.082
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.081
negative regulation of phosphorus metabolic process GO:0010563 184 0.081
g protein coupled receptor signaling pathway GO:0007186 243 0.079
regulation of protein localization GO:0032880 231 0.079
blood circulation GO:0008015 195 0.078
regulation of cell projection organization GO:0031344 206 0.078
positive regulation of bmp signaling pathway GO:0030513 23 0.077
hair cycle GO:0042633 90 0.077
regulation of interleukin 10 secretion GO:2001179 4 0.077
response to extracellular stimulus GO:0009991 127 0.077
negative regulation of cellular protein metabolic process GO:0032269 247 0.077
synaptic transmission GO:0007268 329 0.077
regulation of actin polymerization or depolymerization GO:0008064 45 0.077
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.076
regulation of endopeptidase activity GO:0052548 89 0.076
positive regulation of neuron projection development GO:0010976 79 0.076
response to amino acid GO:0043200 37 0.076
positive regulation of lymphocyte proliferation GO:0050671 70 0.075
positive regulation of intracellular transport GO:0032388 70 0.073
cellular response to amino acid stimulus GO:0071230 29 0.073
adherens junction organization GO:0034332 28 0.073
tube formation GO:0035148 140 0.072
morphogenesis of embryonic epithelium GO:0016331 159 0.070
glucose transport GO:0015758 56 0.070
cellular lipid metabolic process GO:0044255 323 0.070
negative regulation of phosphate metabolic process GO:0045936 184 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.070
lymphocyte proliferation GO:0046651 164 0.070
leukocyte mediated immunity GO:0002443 174 0.069
sensory organ morphogenesis GO:0090596 242 0.069
response to corticosterone GO:0051412 1 0.069
regulation of intracellular transport GO:0032386 159 0.069
cell differentiation involved in kidney development GO:0061005 33 0.068
organic hydroxy compound transport GO:0015850 93 0.068
regulation of cysteine type endopeptidase activity GO:2000116 65 0.068
regulation of striated muscle cell differentiation GO:0051153 81 0.068
cell type specific apoptotic process GO:0097285 268 0.067
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.067
glomerular filtration GO:0003094 7 0.067
neuron migration GO:0001764 122 0.067
positive regulation of peptidase activity GO:0010952 49 0.067
regulation of bmp signaling pathway GO:0030510 60 0.067
positive regulation of programmed cell death GO:0043068 218 0.066
striated muscle tissue development GO:0014706 293 0.066
maintenance of apical basal cell polarity GO:0035090 3 0.066
protein targeting GO:0006605 143 0.065
meiotic cell cycle GO:0051321 122 0.065
guanosine containing compound catabolic process GO:1901069 144 0.065
chemotaxis GO:0006935 247 0.065
negative regulation of molecular function GO:0044092 258 0.064
glucose metabolic process GO:0006006 92 0.064
regulation of wound healing GO:0061041 40 0.064
regulation of secretion GO:0051046 274 0.064
appendage morphogenesis GO:0035107 149 0.063
regulation of protein maturation GO:1903317 96 0.062
endothelial cell apoptotic process GO:0072577 9 0.062
cardiocyte differentiation GO:0035051 87 0.062
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.062
organic hydroxy compound metabolic process GO:1901615 203 0.062
monocarboxylic acid metabolic process GO:0032787 191 0.062
embryonic placenta development GO:0001892 98 0.062
neural tube development GO:0021915 160 0.061
angiogenesis GO:0001525 201 0.061
positive regulation of secretion GO:0051047 130 0.061
carnitine metabolic process GO:0009437 7 0.061
regulation of neuron death GO:1901214 134 0.061
nuclear division GO:0000280 158 0.060
positive regulation of leukocyte proliferation GO:0070665 73 0.059
protein processing GO:0016485 163 0.059
low density lipoprotein particle clearance GO:0034383 8 0.059
carbohydrate homeostasis GO:0033500 128 0.059
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.058
purine nucleoside monophosphate metabolic process GO:0009126 81 0.058
leukocyte proliferation GO:0070661 172 0.058
defense response to protozoan GO:0042832 25 0.057
camera type eye development GO:0043010 266 0.057
sperm individualization GO:0007291 1 0.057
response to molecule of bacterial origin GO:0002237 143 0.057
neurotransmitter uptake GO:0001504 14 0.057
connective tissue development GO:0061448 179 0.056
neural tube formation GO:0001841 108 0.056
humoral immune response GO:0006959 57 0.056
monocarboxylic acid transport GO:0015718 44 0.055
trigeminal sensory nucleus development GO:0021730 2 0.055
odontogenesis GO:0042476 78 0.054
negative regulation of neuron apoptotic process GO:0043524 92 0.054
protein localization to membrane GO:0072657 108 0.054
glomerular visceral epithelial cell differentiation GO:0072112 10 0.054
regulation of apoptotic signaling pathway GO:2001233 197 0.054
positive regulation of cell death GO:0010942 224 0.054
apoptotic mitochondrial changes GO:0008637 48 0.054
positive regulation of lipid storage GO:0010884 10 0.053
regulation of leukocyte mediated immunity GO:0002703 104 0.052
multicellular organismal homeostasis GO:0048871 164 0.052
lipid localization GO:0010876 126 0.052
blood vessel morphogenesis GO:0048514 285 0.052
nucleoside triphosphate catabolic process GO:0009143 205 0.052
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.052
regulation of protein targeting GO:1903533 61 0.051
cation homeostasis GO:0055080 212 0.051
ensheathment of neurons GO:0007272 76 0.051
leukocyte activation involved in immune response GO:0002366 126 0.050
regulation of neuron projection development GO:0010975 169 0.050
regulation of kinase activity GO:0043549 249 0.050
activation of cysteine type endopeptidase activity GO:0097202 27 0.049
regulation of nucleotide metabolic process GO:0006140 169 0.049
regulation of protein processing GO:0070613 96 0.049
cellular response to acid chemical GO:0071229 68 0.049
positive regulation of protein phosphorylation GO:0001934 242 0.049
cell activation involved in immune response GO:0002263 126 0.049
learning or memory GO:0007611 148 0.048
response to fructose GO:0009750 2 0.048
adrenal cortex development GO:0035801 2 0.047
organelle fission GO:0048285 170 0.047
cellular metal ion homeostasis GO:0006875 151 0.047
nerve development GO:0021675 67 0.047
negative regulation of osteoblast proliferation GO:0033689 4 0.047
oviduct development GO:0060066 3 0.046
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.046
cell cell junction assembly GO:0007043 27 0.046
female gamete generation GO:0007292 74 0.045
digestive system development GO:0055123 200 0.045
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.045
inorganic cation transmembrane transport GO:0098662 207 0.045
Mouse
negative regulation of growth GO:0045926 99 0.044
response to oxidative stress GO:0006979 123 0.044
sensory perception GO:0007600 245 0.043
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.043
regulation of myotube differentiation GO:0010830 62 0.043
cellular response to peptide GO:1901653 92 0.043
muscle fiber development GO:0048747 76 0.043
kidney epithelium development GO:0072073 121 0.042
sodium ion transport GO:0006814 73 0.042
Mouse
regulation of production of molecular mediator of immune response GO:0002700 65 0.042
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.042
positive regulation of receptor internalization GO:0002092 4 0.042
lateral motor column neuron migration GO:0097477 3 0.042
cation transmembrane transport GO:0098655 266 0.042
Mouse
positive regulation of cell migration GO:0030335 109 0.041
smooth muscle contraction GO:0006939 44 0.041
inorganic anion transport GO:0015698 43 0.041
adherens junction assembly GO:0034333 22 0.041
myelination GO:0042552 74 0.041
peptidyl tyrosine modification GO:0018212 145 0.041
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.040
glucose import GO:0046323 32 0.040
negative regulation of cellular amine metabolic process GO:0033239 1 0.040
modified amino acid transport GO:0072337 5 0.040
cellular response to hormone stimulus GO:0032870 150 0.040
ras protein signal transduction GO:0007265 77 0.039
rhombomere 3 morphogenesis GO:0021658 2 0.039
gliogenesis GO:0042063 141 0.039
autophagy GO:0006914 45 0.039
skin development GO:0043588 220 0.039
hormone metabolic process GO:0042445 86 0.039
histamine uptake GO:0051615 1 0.038
regulation of peptide transport GO:0090087 91 0.038
cell substrate adhesion GO:0031589 130 0.038
myeloid leukocyte mediated immunity GO:0002444 42 0.038
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.038
positive regulation of growth GO:0045927 104 0.038
cell junction assembly GO:0034329 52 0.038
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.037
mrna 3 end processing GO:0031124 16 0.037
defense response to bacterium GO:0042742 119 0.037
sodium ion transmembrane transport GO:0035725 49 0.037
Mouse
innate immune response GO:0045087 157 0.037
positive regulation of endothelial cell chemotaxis GO:2001028 1 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.037
regulation of extent of cell growth GO:0061387 52 0.037
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.037
protein localization to plasma membrane GO:0072659 57 0.037
adrenal cortex formation GO:0035802 2 0.037
regulation of cell migration GO:0030334 219 0.036
inorganic anion transmembrane transport GO:0098661 29 0.036
regulation of cell size GO:0008361 72 0.036
negative regulation of protein modification process GO:0031400 163 0.036
bmp signaling pathway GO:0030509 93 0.036
regulation of neuron apoptotic process GO:0043523 122 0.036
negative regulation of endopeptidase activity GO:0010951 44 0.036
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.036
negative regulation of vasculature development GO:1901343 26 0.036
leukocyte migration GO:0050900 124 0.036
cellular response to dna damage stimulus GO:0006974 207 0.036
monoamine transport GO:0015844 33 0.035
dopamine uptake involved in synaptic transmission GO:0051583 4 0.035
protein modification by small protein conjugation or removal GO:0070647 207 0.035
myeloid cell differentiation GO:0030099 233 0.035
regulation of establishment of protein localization GO:0070201 181 0.035
axonogenesis GO:0007409 274 0.034
establishment of protein localization to membrane GO:0090150 54 0.034
positive regulation of organelle organization GO:0010638 128 0.034
establishment of monopolar cell polarity GO:0061162 8 0.034
mesenchyme development GO:0060485 152 0.034
stress activated protein kinase signaling cascade GO:0031098 81 0.034
stem cell differentiation GO:0048863 268 0.034
nucleoside monophosphate catabolic process GO:0009125 59 0.034
positive regulation of immune effector process GO:0002699 107 0.034
positive regulation of striated muscle cell differentiation GO:0051155 35 0.034
placenta development GO:0001890 140 0.033
positive regulation of protein transport GO:0051222 93 0.033
neutrophil mediated immunity GO:0002446 19 0.033
carbohydrate derivative biosynthetic process GO:1901137 183 0.033
retina morphogenesis in camera type eye GO:0060042 45 0.033
establishment of protein localization to organelle GO:0072594 118 0.033
filopodium assembly GO:0046847 19 0.033
cellular response to oxygen levels GO:0071453 20 0.033
nuclear transport GO:0051169 139 0.032
somitogenesis GO:0001756 69 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
energy reserve metabolic process GO:0006112 39 0.032
rhombomere 5 development GO:0021571 4 0.032
cellular chemical homeostasis GO:0055082 215 0.032
formation of primary germ layer GO:0001704 77 0.032
negative regulation of protein processing GO:0010955 79 0.032
positive regulation of cytokine production GO:0001819 174 0.032
glial cell differentiation GO:0010001 131 0.032
cellular ion homeostasis GO:0006873 165 0.032
regulation of body fluid levels GO:0050878 162 0.032
fat cell differentiation GO:0045444 160 0.032
regulation of cell motility GO:2000145 236 0.032
cellular response to starvation GO:0009267 57 0.031
positive regulation of necrotic cell death GO:0010940 1 0.031
tissue homeostasis GO:0001894 115 0.031
inflammatory response GO:0006954 244 0.031
regulation of vesicle mediated transport GO:0060627 139 0.031
cellular response to nutrient levels GO:0031669 64 0.031
cell growth GO:0016049 130 0.031
hindbrain development GO:0030902 128 0.031
cellular response to cytokine stimulus GO:0071345 189 0.031
ribonucleoside monophosphate metabolic process GO:0009161 80 0.031
regulation of system process GO:0044057 200 0.031
somite development GO:0061053 81 0.031
embryonic appendage morphogenesis GO:0035113 126 0.030
regulation of inflammatory response GO:0050727 147 0.030
medulla oblongata development GO:0021550 3 0.030
gamma aminobutyric acid metabolic process GO:0009448 3 0.030
leukocyte differentiation GO:0002521 342 0.030
cell junction maintenance GO:0034331 4 0.030
central nervous system neuron development GO:0021954 67 0.030
plasma membrane organization GO:0007009 90 0.030
response to epidermal growth factor GO:0070849 4 0.030
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.029
gastrulation GO:0007369 116 0.029
response to radiation GO:0009314 165 0.029
negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 4 0.029
t cell proliferation GO:0042098 120 0.029
cell recognition GO:0008037 83 0.029
multicellular organism growth GO:0035264 161 0.029
regulation of axon extension GO:0030516 43 0.029
response to oxygen levels GO:0070482 62 0.029
protein targeting to plasma membrane GO:0072661 7 0.029
diaphragm development GO:0060539 5 0.029
norepinephrine transport GO:0015874 2 0.029
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.028
l amino acid transport GO:0015807 32 0.028

Nphs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.896
urinary system disease DOID:18 0 0.896
kidney disease DOID:557 0 0.796
nephritis DOID:10952 0 0.233
glomerulonephritis DOID:2921 0 0.233
focal segmental glomerulosclerosis DOID:1312 0 0.233
glomerulosclerosis DOID:0050851 0 0.233
disease of cellular proliferation DOID:14566 0 0.071
cancer DOID:162 0 0.049
kidney cancer DOID:263 0 0.040
urinary system cancer DOID:3996 0 0.040
organ system cancer DOID:0050686 0 0.040
renal cell carcinoma DOID:4450 0 0.040
renal carcinoma DOID:4451 0 0.040
bone development disease DOID:0080006 0 0.029
bone disease DOID:0080001 0 0.029
musculoskeletal system disease DOID:17 0 0.029
connective tissue disease DOID:65 0 0.029