|
|
regulation of system process
|
GO:0044057 |
200 |
0.461
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.434
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.409
|
Zebrafish |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.323
|
|
|
|
somatostatin signaling pathway
|
GO:0038170 |
2 |
0.234
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.223
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.223
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.223
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.203
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.199
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.199
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.191
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.191
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.182
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.173
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.173
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.171
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.169
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.168
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.167
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.161
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.161
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.160
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.158
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.156
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.146
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.145
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.142
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.140
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.133
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.129
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.127
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.126
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.124
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.123
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.120
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.119
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.119
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.118
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.116
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.115
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.115
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.113
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.111
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.109
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.109
|
Zebrafish |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.107
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.107
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.104
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.104
|
|
|
|
regulation of saliva secretion
|
GO:0046877 |
2 |
0.104
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.104
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.103
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.101
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.100
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.100
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.099
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.098
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.097
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.097
|
|
|
|
anatomical structure arrangement
|
GO:0048532 |
20 |
0.093
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.091
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.090
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.089
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.089
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.088
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.086
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.083
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.082
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.082
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.081
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.081
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.081
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.080
|
|
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.080
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.079
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.079
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.078
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.078
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.078
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.077
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.077
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.076
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.076
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.075
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.073
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.073
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.073
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.072
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.071
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.071
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.071
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.071
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
37 |
0.068
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.068
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.067
|
|
|
|
somatostatin receptor signaling pathway
|
GO:0038169 |
2 |
0.067
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.067
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.066
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.066
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.066
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.066
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.066
|
|
|
|
histamine induced gastric acid secretion
|
GO:0001697 |
1 |
0.066
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.065
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.065
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.063
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.063
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.062
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.061
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.060
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.060
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.059
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.059
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.058
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.058
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.058
|
|
|
|
sensitization
|
GO:0046960 |
2 |
0.057
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.056
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.056
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.056
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.056
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.056
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.056
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.055
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.055
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.055
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.055
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.054
|
|
|
|
cellular response to temperature stimulus
|
GO:0071502 |
2 |
0.054
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.054
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.054
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.053
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.053
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.053
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.053
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.053
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.052
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.052
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.052
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.052
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.052
|
|
|
|
memory
|
GO:0007613 |
58 |
0.051
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.051
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.051
|
|
|
|
g protein coupled glutamate receptor signaling pathway
|
GO:0007216 |
3 |
0.051
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.051
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.050
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.050
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.050
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.050
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.050
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.050
|
|
|
|
horizontal cell localization
|
GO:0035852 |
1 |
0.050
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.049
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.049
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.049
|
|
|
|
mesendoderm development
|
GO:0048382 |
3 |
0.049
|
|
|
|
developmental induction
|
GO:0031128 |
34 |
0.048
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.048
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.048
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.048
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.048
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.048
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.048
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.047
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.047
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.047
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.047
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.046
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.046
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.046
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
36 |
0.045
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.045
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.045
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.044
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.044
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.044
|
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
3 |
0.044
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.044
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.044
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.044
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.044
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.044
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.044
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.043
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
18 |
0.043
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.043
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.043
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.043
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.043
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.043
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.043
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.043
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.042
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.042
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.042
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.042
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.042
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.042
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.042
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.042
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.042
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.042
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.042
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.041
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.041
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.041
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.041
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.041
|
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
1 |
0.041
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.041
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.041
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.041
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
53 |
0.040
|
|
|
|
somatotropin secreting cell development
|
GO:0060133 |
2 |
0.040
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.040
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.040
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.040
|
|
|
|
renal system process
|
GO:0003014 |
48 |
0.040
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.040
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.040
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.040
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.040
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.039
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
15 |
0.039
|
|
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.039
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.039
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.039
|
|
|
|
positive regulation of g0 to g1 transition
|
GO:0070318 |
2 |
0.039
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.039
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.039
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.039
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.038
|
|
|
|
thyroid stimulating hormone secreting cell differentiation
|
GO:0060129 |
4 |
0.038
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.038
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.038
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.037
|
|
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
8 |
0.037
|
|
|
|
potassium ion homeostasis
|
GO:0055075 |
4 |
0.037
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.036
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.036
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.036
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.036
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.036
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.036
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.036
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.036
|
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.035
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.035
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.035
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.035
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.035
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.034
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.034
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.034
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.034
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.034
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.034
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.034
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.034
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.034
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.034
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.033
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.033
|
|
|
|
pigment biosynthetic process
|
GO:0046148 |
26 |
0.033
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.033
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.033
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.033
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.033
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.033
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.033
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.033
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.033
|
|
|
|
pons development
|
GO:0021548 |
13 |
0.033
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.032
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.032
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.032
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.032
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.032
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.032
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.032
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.032
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.032
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.032
|
Zebrafish |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.032
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.031
|
|
|
|
gastrin induced gastric acid secretion
|
GO:0001698 |
1 |
0.031
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.031
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.031
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.031
|
|
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.031
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.031
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.031
|
|
|
|
morphogenesis of an epithelial fold
|
GO:0060571 |
28 |
0.031
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.031
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.031
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.031
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.031
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.031
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.031
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.031
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.031
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.030
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.030
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry
|
GO:1900094 |
2 |
0.030
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.030
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.030
|
|
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.030
|
|
|
|
vestibular nucleus development
|
GO:0021750 |
2 |
0.030
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.030
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.029
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.029
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.029
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.029
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
22 |
0.029
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.029
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.029
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.029
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.029
|
|
|
|
learning
|
GO:0007612 |
98 |
0.029
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.029
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.029
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.029
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.029
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.028
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.028
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.028
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.028
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.028
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.028
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.028
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.028
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.028
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.028
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.028
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.028
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.028
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.028
|
|
|
|
stem cell fate specification
|
GO:0048866 |
3 |
0.028
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.028
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.027
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.027
|
|
|
|
glycolytic process
|
GO:0006096 |
20 |
0.027
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.027
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.027
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.027
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.027
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
49 |
0.027
|
|
|
|
substantia nigra development
|
GO:0021762 |
2 |
0.027
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.027
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.027
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.027
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.026
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.026
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.026
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.026
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.026
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.026
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.026
|
|
|
|
satellite cell activation involved in skeletal muscle regeneration
|
GO:0014901 |
3 |
0.026
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.026
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.026
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.026
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.026
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.026
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.026
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.025
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.025
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.025
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.025
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.025
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.025
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.025
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.025
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.025
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.025
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
35 |
0.025
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.025
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.025
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.025
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.025
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.025
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.024
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.024
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.024
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.024
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.024
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.024
|
Mouse |
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.024
|
|
|
|
regulation of satellite cell activation involved in skeletal muscle regeneration
|
GO:0014717 |
3 |
0.024
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.024
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.024
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.023
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
22 |
0.023
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.023
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.023
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.023
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.023
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.023
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.023
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.023
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.023
|
|
|
|
positive regulation of voltage gated calcium channel activity
|
GO:1901387 |
2 |
0.023
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.023
|
|
|
|
dopamine receptor signaling pathway
|
GO:0007212 |
16 |
0.023
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.023
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
13 |
0.022
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.022
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.022
|
|
|
|
gas homeostasis
|
GO:0033483 |
3 |
0.022
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.022
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.022
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.022
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.022
|
|
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.022
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.022
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.022
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.022
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.022
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.022
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.022
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.022
|
|
|
|
schwann cell proliferation
|
GO:0014010 |
2 |
0.022
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.021
|
|
|
|
regulation of g protein activated inward rectifier potassium channel activity
|
GO:1900128 |
1 |
0.021
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.021
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.021
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.021
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.021
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.021
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.021
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.021
|
Zebrafish |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.021
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.021
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.021
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.021
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.021
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.021
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
17 |
0.021
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.021
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.021
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.021
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.021
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.021
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.021
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.021
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.021
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
3 |
0.020
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.020
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.020
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.020
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
2 |
0.020
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.020
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.020
|
|
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
3 |
0.020
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.020
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.020
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.020
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.020
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.020
|
|
|
|
embryonic genitalia morphogenesis
|
GO:0030538 |
4 |
0.020
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.020
|
|
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
2 |
0.020
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.020
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
4 |
0.020
|
|
|
|
phasic smooth muscle contraction
|
GO:0014821 |
8 |
0.020
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
29 |
0.020
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.020
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.020
|
|
|
|
mitral valve development
|
GO:0003174 |
4 |
0.020
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.020
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.019
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.019
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.019
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.019
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.019
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.019
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
54 |
0.019
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.019
|
|
|
|
acid secretion
|
GO:0046717 |
33 |
0.019
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.019
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.019
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.019
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.019
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.019
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.019
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.019
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.019
|
|
|
|
fast calcium ion dependent exocytosis of neurotransmitter
|
GO:0098746 |
1 |
0.019
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.019
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.019
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.019
|
|
