|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.997
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.994
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.993
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.992
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.989
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.980
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.975
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.972
|
Rat |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.969
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.969
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.964
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.959
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.949
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.944
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.936
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.936
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.936
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.935
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.930
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.926
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.923
|
Mouse Rat |
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.919
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.915
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.914
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.908
|
|
|
|
oxygen homeostasis
|
GO:0032364 |
2 |
0.908
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.895
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.894
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.892
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.889
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.884
|
Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.883
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.882
|
Rat |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.882
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.865
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.860
|
Rat |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.858
|
|
|
|
memory
|
GO:0007613 |
58 |
0.857
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.852
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.850
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.850
|
Mouse |
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.850
|
|
|
|
regulation of glucocorticoid secretion
|
GO:2000849 |
5 |
0.847
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.845
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.844
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.843
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.839
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.839
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
8 |
0.837
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.834
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.833
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.831
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.828
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.818
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.817
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.815
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.811
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.811
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.804
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.802
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.789
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.789
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.782
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.780
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.779
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.778
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.773
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.770
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.767
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.766
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.766
|
Mouse |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.764
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.763
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.762
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.755
|
Rat |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.748
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.746
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.746
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.745
|
Rat |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.741
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.731
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.731
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.729
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.727
|
Rat |
|
|
glycolytic process
|
GO:0006096 |
20 |
0.725
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.720
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.716
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.715
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.713
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.709
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.708
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.704
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.700
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.699
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.695
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.694
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.686
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.684
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.683
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.674
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.674
|
|
|
|
regulation of carbohydrate catabolic process
|
GO:0043470 |
12 |
0.673
|
|
|
|
positive regulation of dendrite development
|
GO:1900006 |
21 |
0.672
|
Rat |
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.672
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.672
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.669
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.661
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.661
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.660
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.659
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.657
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.656
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.655
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.650
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.645
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.644
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.643
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.641
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.640
|
Rat |
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.640
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.635
|
Mouse |
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
9 |
0.632
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.629
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.628
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.625
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.624
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.624
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.623
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.622
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.615
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.613
|
Rat |
|
|
associative learning
|
GO:0008306 |
61 |
0.612
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.611
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.609
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.605
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.602
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.601
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
20 |
0.594
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.593
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.593
|
|
|
|
neural fold elevation formation
|
GO:0021502 |
1 |
0.590
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.589
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.589
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.587
|
Zebrafish Rat |
|
|
heart trabecula formation
|
GO:0060347 |
14 |
0.585
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.582
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.582
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.581
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
18 |
0.580
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.580
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.580
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.579
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.578
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.577
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.571
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.566
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.565
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.564
|
Rat |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.563
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.563
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.562
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.562
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.559
|
|
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
4 |
0.557
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.555
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.554
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.551
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.551
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.546
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.545
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.545
|
|
|
|
b 1 b cell homeostasis
|
GO:0001922 |
4 |
0.542
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.538
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.538
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.537
|
Rat |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.533
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.529
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.525
|
Rat |
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.525
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.522
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.522
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.522
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.520
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.520
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.517
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.517
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.516
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.515
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.515
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.513
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.511
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.511
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.510
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.507
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.505
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.502
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.500
|
|
|
|
negative regulation of neurotransmitter transport
|
GO:0051589 |
7 |
0.499
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
39 |
0.497
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.495
|
|
|
|
positive regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0035774 |
13 |
0.495
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.495
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
33 |
0.491
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.490
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.490
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.489
|
|
|
|
cellular response to drug
|
GO:0035690 |
15 |
0.487
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.486
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.483
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.482
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.482
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.478
|
Rat |
|
|
negative regulation of tor signaling
|
GO:0032007 |
13 |
0.476
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.476
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.475
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.473
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.472
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.471
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.468
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.468
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.467
|
Rat |
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.466
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.466
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.464
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.458
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.452
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.446
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.445
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.444
|
Rat |
|
|
visual learning
|
GO:0008542 |
44 |
0.443
|
|
|
|
catecholamine metabolic process
|
GO:0006584 |
30 |
0.443
|
|
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
9 |
0.441
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.441
|
Rat |
|
|
wound healing
|
GO:0042060 |
157 |
0.437
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.436
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
32 |
0.434
|
|
|
|
epithelial cell differentiation involved in mammary gland alveolus development
|
GO:0061030 |
4 |
0.431
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.426
|
|
|
|
learning
|
GO:0007612 |
98 |
0.425
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.423
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.423
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.422
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.420
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.420
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.420
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.415
|
|
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
31 |
0.411
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.408
|
Rat |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.406
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.404
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.403
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.403
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.401
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.400
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.400
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.399
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.398
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.396
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.394
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.393
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.393
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.393
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.392
|
Rat |
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.391
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.391
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.390
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.390
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.390
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.389
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.386
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.385
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.384
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.384
|
|
|
|
regulation of corticosteroid hormone secretion
|
GO:2000846 |
5 |
0.379
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.379
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.379
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.378
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.378
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.376
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.376
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.376
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.372
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.372
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.371
|
Zebrafish |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.370
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.369
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.367
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.367
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.366
|
Zebrafish |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.366
|
|
|
|
connective tissue replacement involved in inflammatory response wound healing
|
GO:0002248 |
3 |
0.366
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.364
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.363
|
|
|
|
cellular carbohydrate catabolic process
|
GO:0044275 |
15 |
0.362
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.360
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.358
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.358
|
Rat |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.358
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.356
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.355
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.355
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.354
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.354
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
49 |
0.354
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.352
|
|
|
|
glucocorticoid secretion
|
GO:0035933 |
6 |
0.351
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.350
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.349
|
Rat |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
13 |
0.349
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.348
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.348
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.347
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
31 |
0.346
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.346
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.346
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.344
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.344
|
Rat |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.341
|
Rat |
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.341
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.340
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.338
|
|
|
|
regulation of t cell apoptotic process
|
GO:0070232 |
28 |
0.338
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.336
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.335
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.335
|
Rat |
|
|
sensory perception
|
GO:0007600 |
245 |
0.334
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.334
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.333
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.332
|
|
|
|
hypoxia inducible factor 1alpha signaling pathway
|
GO:0097411 |
2 |
0.332
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.331
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.331
|
Rat |
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
26 |
0.329
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.329
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.329
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.327
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.325
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.324
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
14 |
0.323
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.322
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
17 |
0.320
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.318
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.318
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.317
|
|
|
|
gas homeostasis
|
GO:0033483 |
3 |
0.316
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.315
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.312
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.311
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.310
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.309
|
|
|
|
regulation of fear response
|
GO:1903365 |
2 |
0.309
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.308
|
|
|
|
organic hydroxy compound catabolic process
|
GO:1901616 |
25 |
0.308
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.306
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.306
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.306
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.305
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.302
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.302
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.300
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.297
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to oxidative stress
|
GO:0043619 |
2 |
0.297
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.295
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.295
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.295
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.294
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.293
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.291
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.290
|
|
|
|
cardiac muscle tissue growth
|
GO:0055017 |
37 |
0.290
|
Rat |
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.289
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.288
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.288
|
Mouse |
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
19 |
0.287
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.284
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.283
|
|
|
|
wound healing involved in inflammatory response
|
GO:0002246 |
4 |
0.282
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.281
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
28 |
0.281
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.280
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.280
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.280
|
Rat |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.280
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.279
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.277
|
Rat |
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.277
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.276
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.276
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.275
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.274
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.273
|
|
|
|
purine ribonucleoside biosynthetic process
|
GO:0046129 |
19 |
0.273
|
|
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
4 |
0.273
|
|
|
|
corticosterone secretion
|
GO:0035934 |
3 |
0.270
|
|
|
|
circadian behavior
|
GO:0048512 |
13 |
0.270
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.267
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
28 |
0.265
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.264
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.262
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.262
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.262
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.261
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.261
|
|
|
|
negative regulation of thymocyte apoptotic process
|
GO:0070244 |
8 |
0.261
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.259
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.257
|
Rat |
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.257
|
|
|
|
regulation of behavioral fear response
|
GO:2000822 |
2 |
0.252
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.250
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.249
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.249
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.249
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.249
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.248
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.248
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
43 |
0.247
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.246
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.246
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.245
|
Mouse |
|
|
germinal center formation
|
GO:0002467 |
16 |
0.245
|
|
|
|
positive regulation of epidermal growth factor activated receptor activity
|
GO:0045741 |
2 |
0.245
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.245
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.245
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.245
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.244
|
|
|
|
response to corticosteroid
|
GO:0031960 |
20 |
0.244
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
23 |
0.243
|
|
|
|
regulation of mast cell apoptotic process
|
GO:0033025 |
5 |
0.243
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.243
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.242
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.242
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.241
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.241
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.240
|
|
|
|
vitamin transmembrane transport
|
GO:0035461 |
4 |
0.240
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.239
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.239
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.237
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.237
|
Rat |
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.236
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.236
|
Rat |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.235
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.234
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.234
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.233
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.233
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.232
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.232
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.231
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.231
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.231
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.231
|
|
|
|
endocrine process
|
GO:0050886 |
39 |
0.230
|
|
|
|
muscle cell cellular homeostasis
|
GO:0046716 |
12 |
0.229
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.229
|
Rat |
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.228
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.228
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.227
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.227
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.226
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.226
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.225
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.224
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
10 |
0.223
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.223
|
|
|
|
regulation of corticosterone secretion
|
GO:2000852 |
2 |
0.223
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.222
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.222
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.221
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.220
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.219
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.218
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.218
|
|
|
|
positive regulation of sodium ion transport
|
GO:0010765 |
13 |
0.217
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.217
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.216
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
3 |
0.216
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.214
|
|
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.213
|
|
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.213
|
|
|
|
negative regulation of peptide hormone secretion
|
GO:0090278 |
16 |
0.212
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.211
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.209
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.208
|
|
|
|
prolactin signaling pathway
|
GO:0038161 |
5 |
0.208
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.208
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.208
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.208
|
Zebrafish Mouse |
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.208
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
44 |
0.207
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.207
|
|
|
|
regulation of serotonin uptake
|
GO:0051611 |
2 |
0.207
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.206
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.205
|
|
