Mus musculus

0 known processes

Nradd

neurotrophin receptor associated death domain

(Aliases: PLAIDD,2610311B09Rik,NRDD,BB104149)

Nradd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of lipoprotein lipase activity GO:0051004 4 0.550
carbohydrate transport GO:0008643 62 0.191
negative regulation of lipoprotein lipase activity GO:0051005 1 0.139
mapk cascade GO:0000165 281 0.137
regulation of protein kinase activity GO:0045859 232 0.131
regulation of mapk cascade GO:0043408 248 0.127
regulation of kinase activity GO:0043549 249 0.124
cellular amino acid metabolic process GO:0006520 103 0.119
negative regulation of inclusion body assembly GO:0090084 1 0.118
regulation of neuron death GO:1901214 134 0.114
negative regulation of kinase activity GO:0033673 81 0.107
response to organonitrogen compound GO:0010243 246 0.107
g protein coupled receptor signaling pathway GO:0007186 243 0.102
golgi to endosome transport GO:0006895 3 0.098
negative regulation of molecular function GO:0044092 258 0.096
negative regulation of phosphorus metabolic process GO:0010563 184 0.094
regulation of neuron differentiation GO:0045664 281 0.094
ras protein signal transduction GO:0007265 77 0.091
negative regulation of phosphorylation GO:0042326 166 0.091
negative regulation of cellular component organization GO:0051129 194 0.085
neuron death GO:0070997 154 0.083
regulation of cellular amino acid metabolic process GO:0006521 5 0.081
small gtpase mediated signal transduction GO:0007264 97 0.077
extrinsic apoptotic signaling pathway GO:0097191 126 0.076
negative regulation of nervous system development GO:0051961 156 0.074
negative regulation of phosphate metabolic process GO:0045936 184 0.073
negative regulation of cellular amide metabolic process GO:0034249 4 0.073
hexose transport GO:0008645 56 0.072
regulation of protein serine threonine kinase activity GO:0071900 157 0.071
positive regulation of apoptotic signaling pathway GO:2001235 95 0.071
regulation of cellular ketone metabolic process GO:0010565 66 0.071
protein maturation GO:0051604 176 0.070
response to peptide GO:1901652 136 0.068
monosaccharide transport GO:0015749 58 0.068
negative regulation of cellular protein metabolic process GO:0032269 247 0.067
negative regulation of intracellular signal transduction GO:1902532 167 0.067
negative regulation of lipase activity GO:0060192 7 0.067
negative regulation of hydrolase activity GO:0051346 71 0.066
positive regulation of mapk cascade GO:0043410 170 0.066
cellular amine metabolic process GO:0044106 44 0.066
membrane depolarization GO:0051899 64 0.066
response to peptide hormone GO:0043434 127 0.064
negative regulation of neuron death GO:1901215 98 0.062
protein processing GO:0016485 163 0.062
rho protein signal transduction GO:0007266 32 0.061
negative regulation of transferase activity GO:0051348 85 0.061
reactive oxygen species metabolic process GO:0072593 84 0.059
amine metabolic process GO:0009308 45 0.059
negative regulation of proteolysis GO:0045861 74 0.059
positive regulation of programmed cell death GO:0043068 218 0.058
muscle cell differentiation GO:0042692 261 0.058
nerve growth factor signaling pathway GO:0038180 3 0.056
vesicle organization GO:0016050 60 0.055
circadian regulation of gene expression GO:0032922 48 0.055
cytoplasmic transport GO:0016482 234 0.055
inclusion body assembly GO:0070841 3 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
negative regulation of protein phosphorylation GO:0001933 126 0.054
regulation of map kinase activity GO:0043405 120 0.053
regulation of inclusion body assembly GO:0090083 1 0.052
cellular ketone metabolic process GO:0042180 84 0.052
regulation of transferase activity GO:0051338 263 0.050
multicellular organismal signaling GO:0035637 91 0.050
regulation of peptidase activity GO:0052547 96 0.050
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.050
synaptic transmission GO:0007268 329 0.050
regulation of apoptotic signaling pathway GO:2001233 197 0.049
negative regulation of map kinase activity GO:0043407 34 0.049
response to insulin GO:0032868 100 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.047
cation transport GO:0006812 399 0.046
negative regulation of cell development GO:0010721 169 0.046
response to nerve growth factor GO:1990089 3 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.044
regulation of hydrolase activity GO:0051336 246 0.044
negative regulation of cell projection organization GO:0031345 56 0.043
regulation of reactive oxygen species metabolic process GO:2000377 40 0.041
positive regulation of apoptotic process GO:0043065 217 0.041
apoptotic signaling pathway GO:0097190 306 0.040
wnt signaling pathway GO:0016055 188 0.040
response to oxidative stress GO:0006979 123 0.039
protein localization to organelle GO:0033365 185 0.039
peptidyl amino acid modification GO:0018193 336 0.039
response to lipopolysaccharide GO:0032496 128 0.038
negative regulation of protein metabolic process GO:0051248 282 0.038
neuronal action potential GO:0019228 54 0.037
regulation of proteolysis GO:0030162 164 0.037
regulation of membrane potential GO:0042391 192 0.036
intracellular protein transport GO:0006886 204 0.036
negative regulation of protein modification process GO:0031400 163 0.036
cellular response to oxidative stress GO:0034599 76 0.036
myotube differentiation GO:0014902 105 0.036
ion transmembrane transport GO:0034220 361 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.036
positive regulation of transferase activity GO:0051347 167 0.035
response to growth factor GO:0070848 198 0.035
regulation of cellular component size GO:0032535 121 0.035
negative regulation of protein processing GO:0010955 79 0.035
glucose transport GO:0015758 56 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
urogenital system development GO:0001655 261 0.034
cell adhesion GO:0007155 329 0.034
neurotrophin signaling pathway GO:0038179 12 0.034
positive regulation of protein modification process GO:0031401 299 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.032
action potential GO:0001508 78 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.032
regulation of cellular catabolic process GO:0031329 242 0.031
cellular response to organonitrogen compound GO:0071417 145 0.031
cell type specific apoptotic process GO:0097285 268 0.031
cellular response to hormone stimulus GO:0032870 150 0.031
carbohydrate homeostasis GO:0033500 128 0.031
nucleoside phosphate catabolic process GO:1901292 222 0.030
canonical wnt signaling pathway GO:0060070 130 0.030
muscle tissue development GO:0060537 308 0.030
regulation of protein processing GO:0070613 96 0.030
cation transmembrane transport GO:0098655 266 0.030
endocytosis GO:0006897 168 0.029
positive regulation of cell death GO:0010942 224 0.029
Rat
regulation of cellular response to growth factor stimulus GO:0090287 82 0.029
positive regulation of nervous system development GO:0051962 221 0.029
skeletal muscle organ development GO:0060538 163 0.028
regulation of protein maturation GO:1903317 96 0.028
asymmetric neuroblast division GO:0055059 1 0.028
negative regulation of mapk cascade GO:0043409 65 0.028
chemotaxis GO:0006935 247 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
regulation of cell projection organization GO:0031344 206 0.027
regulation of neuron projection development GO:0010975 169 0.027
transmembrane transport GO:0055085 412 0.027
purine containing compound metabolic process GO:0072521 311 0.027
oxidation reduction process GO:0055114 342 0.027
regulation of organelle organization GO:0033043 289 0.027
regulation of endopeptidase activity GO:0052548 89 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process GO:1902962 2 0.026
glucose import GO:0046323 32 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.026
sensory organ morphogenesis GO:0090596 242 0.026
transmission of nerve impulse GO:0019226 76 0.026
lysosomal transport GO:0007041 10 0.025
negative regulation of protein maturation GO:1903318 79 0.025
regulation of membrane depolarization GO:0003254 11 0.025
regulation of interleukin 8 production GO:0032677 3 0.025
regulation of cell activation GO:0050865 289 0.025
regulation of response to wounding GO:1903034 189 0.025
aromatic compound catabolic process GO:0019439 286 0.025
negative regulation of endopeptidase activity GO:0010951 44 0.025
camera type eye development GO:0043010 266 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.024
cellular response to insulin stimulus GO:0032869 78 0.024
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.024
membrane organization GO:0061024 245 0.024
cellular amide metabolic process GO:0043603 58 0.024
neuropeptide signaling pathway GO:0007218 19 0.024
regulation of wnt signaling pathway GO:0030111 123 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
cellular response to lipid GO:0071396 145 0.023
regulation of myelination GO:0031641 20 0.023
negative regulation of wnt signaling pathway GO:0030178 73 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
positive regulation of neuron differentiation GO:0045666 141 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
negative regulation of neuron projection development GO:0010977 50 0.022
regulation of canonical wnt signaling pathway GO:0060828 82 0.022
glycoprotein metabolic process GO:0009100 116 0.022
regulation of system process GO:0044057 200 0.021
organic anion transport GO:0015711 137 0.021
negative regulation of neuron differentiation GO:0045665 101 0.021
cytokine production GO:0001816 319 0.021
regulation of neuron apoptotic process GO:0043523 122 0.021
metal ion homeostasis GO:0055065 189 0.021
striated muscle tissue development GO:0014706 293 0.021
glucose homeostasis GO:0042593 128 0.021
skeletal system morphogenesis GO:0048705 203 0.020
regulation of mitochondrial depolarization GO:0051900 5 0.020
extracellular structure organization GO:0043062 148 0.020
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.020
leukocyte differentiation GO:0002521 342 0.020
immune effector process GO:0002252 321 0.020
wound healing GO:0042060 157 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
divalent inorganic cation transport GO:0072511 178 0.020
interleukin 8 production GO:0032637 4 0.020
regulation of mitochondrial membrane potential GO:0051881 17 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
ribonucleotide catabolic process GO:0009261 208 0.019
positive regulation of myelination GO:0031643 5 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
regulation of gtp catabolic process GO:0033124 113 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
response to fibroblast growth factor GO:0071774 47 0.019
positive regulation of growth GO:0045927 104 0.019
peptide metabolic process GO:0006518 46 0.019
neuron apoptotic process GO:0051402 142 0.019
sensory perception GO:0007600 245 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
regulation of epidermis development GO:0045682 33 0.018
protein retention in golgi apparatus GO:0045053 1 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
small molecule biosynthetic process GO:0044283 132 0.018
post golgi vesicle mediated transport GO:0006892 13 0.018
male gamete generation GO:0048232 285 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
regulation of neurological system process GO:0031644 22 0.018
lipid biosynthetic process GO:0008610 179 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
negative regulation of peptidase activity GO:0010466 46 0.018
regulation of homeostatic process GO:0032844 182 0.018
positive regulation of cell development GO:0010720 237 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
forebrain development GO:0030900 302 0.018
anion transport GO:0006820 177 0.018
regulation of synaptic transmission glutamatergic GO:0051966 19 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
purine containing compound catabolic process GO:0072523 213 0.017
spermatogenesis GO:0007283 284 0.017
regulation of lipase activity GO:0060191 15 0.017
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.017
regulation of cellular response to stress GO:0080135 159 0.017
macromolecule catabolic process GO:0009057 281 0.017
divalent metal ion transport GO:0070838 172 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
carbohydrate metabolic process GO:0005975 230 0.017
interleukin 8 secretion GO:0072606 3 0.017
response to inorganic substance GO:0010035 96 0.017
cellular chemical homeostasis GO:0055082 215 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
morphogenesis of a polarized epithelium GO:0001738 37 0.017
nucleotide metabolic process GO:0009117 332 0.017
sensory system development GO:0048880 3 0.016
regulation of interleukin 8 secretion GO:2000482 2 0.016
asymmetric stem cell division GO:0098722 3 0.016
establishment of planar polarity GO:0001736 28 0.016
epidermis development GO:0008544 187 0.016
organophosphate catabolic process GO:0046434 232 0.016
response to temperature stimulus GO:0009266 55 0.016
epithelial cell proliferation GO:0050673 174 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
innate immune response GO:0045087 157 0.016
ameboidal type cell migration GO:0001667 128 0.016
regulation of ion transport GO:0043269 215 0.016
ensheathment of neurons GO:0007272 76 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
learning or memory GO:0007611 148 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
positive regulation of neuron projection development GO:0010976 79 0.015
dna repair GO:0006281 107 0.015
regulation of t cell activation GO:0050863 170 0.015
alpha amino acid metabolic process GO:1901605 59 0.015
sulfur compound metabolic process GO:0006790 100 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
ear morphogenesis GO:0042471 118 0.015
detection of abiotic stimulus GO:0009582 60 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
muscle fiber development GO:0048747 76 0.015
regulation of asymmetric cell division GO:0009786 4 0.015
protein kinase b signaling GO:0043491 74 0.015
regulation of protein kinase b signaling GO:0051896 56 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
developmental maturation GO:0021700 193 0.014
cellular homeostasis GO:0019725 240 0.014
odontogenesis GO:0042476 78 0.014
regulation of cell motility GO:2000145 236 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
organic acid transport GO:0015849 101 0.014
maintenance of location GO:0051235 89 0.014
lymphocyte proliferation GO:0046651 164 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
regionalization GO:0003002 337 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
regulation of hormone levels GO:0010817 211 0.014
negative regulation of beta amyloid formation GO:1902430 4 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
cellular response to peptide GO:1901653 92 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
skeletal system development GO:0001501 356 0.014
kidney development GO:0001822 213 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
positive regulation of kinase activity GO:0033674 155 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.014
circadian rhythm GO:0007623 114 0.014
oocyte axis specification GO:0007309 2 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
b cell activation GO:0042113 161 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
cell substrate adhesion GO:0031589 130 0.013
neurotrophin trk receptor signaling pathway GO:0048011 8 0.013
lymphocyte differentiation GO:0030098 242 0.013
response to oxygen levels GO:0070482 62 0.013
connective tissue development GO:0061448 179 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
peptidyl serine modification GO:0018209 83 0.013
cation homeostasis GO:0055080 212 0.013
rhythmic process GO:0048511 174 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
nerve development GO:0021675 67 0.013
synaptic transmission glutamatergic GO:0035249 36 0.013
chromatin modification GO:0016568 187 0.013
t cell activation GO:0042110 289 0.013
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.013
exocytosis GO:0006887 121 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
protein ubiquitination GO:0016567 171 0.013
response to radiation GO:0009314 165 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
compound eye development GO:0048749 1 0.013
protein localization to membrane GO:0072657 108 0.012
skeletal muscle cell differentiation GO:0035914 66 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
positive regulation of cell activation GO:0050867 158 0.012
hair cycle GO:0042633 90 0.012
dna metabolic process GO:0006259 303 0.012
cell maturation GO:0048469 127 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
protein catabolic process GO:0030163 221 0.012
cellular ion homeostasis GO:0006873 165 0.012
fertilization GO:0009566 127 0.012
regulation of blood pressure GO:0008217 93 0.012
cellular lipid metabolic process GO:0044255 323 0.012
positive regulation of interleukin 8 production GO:0032757 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
heterocycle catabolic process GO:0046700 280 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
mitochondrial depolarization GO:0051882 6 0.012
cognition GO:0050890 149 0.012
stem cell development GO:0048864 219 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
detection of external stimulus GO:0009581 61 0.012
amino acid transport GO:0006865 61 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
extracellular matrix organization GO:0030198 147 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
gliogenesis GO:0042063 141 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
chromatin organization GO:0006325 206 0.012
fat cell differentiation GO:0045444 160 0.012
gland development GO:0048732 330 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
protein polymerization GO:0051258 57 0.012
regulation of hair cycle GO:0042634 11 0.012
nucleoside metabolic process GO:0009116 246 0.012
negative regulation of cell activation GO:0050866 111 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
homeostasis of number of cells GO:0048872 210 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
regulation of ovulation GO:0060278 3 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
cellular response to nerve growth factor stimulus GO:1990090 3 0.011
establishment of tissue polarity GO:0007164 28 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
histone modification GO:0016570 159 0.011
nucleotide catabolic process GO:0009166 217 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
meiotic nuclear division GO:0007126 115 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of organelle organization GO:0010638 128 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
skin development GO:0043588 220 0.011
molting cycle GO:0042303 90 0.011
mesonephros development GO:0001823 97 0.011
regulation of cell size GO:0008361 72 0.011
regulation of secretion GO:0051046 274 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of glucose import in response to insulin stimulus GO:2001273 8 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
regulation of fibroblast proliferation GO:0048145 34 0.010
response to organic cyclic compound GO:0014070 198 0.010
positive regulation of neuron death GO:1901216 28 0.010
microtubule based process GO:0007017 236 0.010
positive regulation of proteolysis GO:0045862 85 0.010
nephron development GO:0072006 109 0.010
positive regulation of fibroblast proliferation GO:0048146 20 0.010
golgi vesicle transport GO:0048193 30 0.010
cardiac chamber development GO:0003205 108 0.010
actin cytoskeleton organization GO:0030036 220 0.010
actin filament organization GO:0007015 113 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
rac protein signal transduction GO:0016601 13 0.010
cell division GO:0051301 120 0.010
b cell differentiation GO:0030183 78 0.010
pharynx development GO:0060465 1 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.010
muscle contraction GO:0006936 101 0.010
regulation of glucose import GO:0046324 26 0.010
sensory perception of pain GO:0019233 47 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
interleukin 6 production GO:0032635 58 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
response to light stimulus GO:0009416 135 0.010
myosin filament organization GO:0031033 3 0.010
single fertilization GO:0007338 82 0.010
gastrulation GO:0007369 116 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
intestinal epithelial structure maintenance GO:0060729 4 0.010

Nradd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
disease of cellular proliferation DOID:14566 0 0.015
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
bone development disease DOID:0080006 0 0.012
neuropathy DOID:870 0 0.011