|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.666
|
Yeast |
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
3 |
0.406
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.321
|
Mouse |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.309
|
Yeast Mouse Worm Fly |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.291
|
Yeast Mouse Worm Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.270
|
Yeast Mouse Worm Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.238
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.225
|
Mouse |
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.210
|
Yeast |
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
4 |
0.203
|
Yeast |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.201
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.199
|
Yeast Mouse Worm Fly |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.197
|
Fly |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.185
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.179
|
|
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.155
|
Yeast |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.155
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.151
|
Mouse |
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.142
|
Yeast |
|
|
regulation of lyase activity
|
GO:0051339 |
13 |
0.138
|
Yeast |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.136
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.136
|
Yeast Mouse Worm Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.134
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.133
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.130
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.129
|
Yeast Mouse Worm Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.126
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.122
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.116
|
Yeast Mouse Worm Fly |
|
|
cell growth
|
GO:0016049 |
130 |
0.112
|
Yeast Fly |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.108
|
Yeast Mouse Worm Fly |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.104
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.101
|
Yeast |
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.100
|
Yeast |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.099
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.098
|
Yeast Mouse Worm Fly |
|
|
protein import
|
GO:0017038 |
101 |
0.097
|
Fly |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.097
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.096
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.094
|
Yeast Mouse Worm Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.089
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.089
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.088
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.087
|
Yeast Mouse Worm Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.086
|
Yeast Mouse Worm Fly |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.086
|
Fly |
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.085
|
Yeast |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.084
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.084
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.083
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.081
|
Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.080
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.079
|
Yeast Mouse Worm Fly |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.076
|
Yeast |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.076
|
Worm Fly |
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.075
|
Yeast |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.074
|
Yeast Mouse Worm Fly |
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.074
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.073
|
Yeast |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.073
|
Worm |
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.073
|
Worm |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.072
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.072
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.071
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.070
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.068
|
Yeast |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.068
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.068
|
Yeast Mouse Worm Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.066
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.066
|
Yeast Mouse Worm Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.065
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.065
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.065
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.064
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.064
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.064
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.064
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.063
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.063
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.062
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.062
|
Yeast Mouse Worm Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.061
|
Yeast Mouse Worm Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.061
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.060
|
Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.060
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.059
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.059
|
Yeast |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.059
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.058
|
Yeast Mouse Worm Fly |
|
|
wound healing
|
GO:0042060 |
157 |
0.058
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.057
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.057
|
Yeast Mouse Worm Fly |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.057
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.056
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.056
|
Yeast Mouse Worm Fly |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.056
|
Yeast |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.056
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
21 |
0.056
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.056
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.055
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.054
|
Fly |
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.054
|
|
|
|
positive regulation of rac protein signal transduction
|
GO:0035022 |
1 |
0.054
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.053
|
Yeast Mouse Worm Fly |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.053
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.053
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.053
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.053
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.051
|
Yeast Mouse Worm Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.051
|
Yeast Mouse Worm Fly |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.051
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.051
|
Yeast |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.050
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.050
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.050
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.049
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.049
|
Yeast Mouse Worm Fly |
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.048
|
Yeast |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.048
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.048
|
Fly |
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.047
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.047
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.047
|
Fly |
|
|
positive regulation of cyclase activity
|
GO:0031281 |
11 |
0.047
|
Yeast |
|
|
cell division
|
GO:0051301 |
120 |
0.047
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.047
|
Fly |
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.046
|
Yeast |
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.046
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.045
|
Mouse |
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.045
|
Fly |
|
|
regulation of cyclase activity
|
GO:0031279 |
13 |
0.044
|
Yeast |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.043
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.043
|
Mouse |
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.043
|
Yeast |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.043
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.042
|
Yeast Mouse Worm Fly |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.042
|
Fly |
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.041
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.041
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.041
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.041
|
Fly |
|
|
appendage development
|
GO:0048736 |
166 |
0.040
|
Fly |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.040
|
Yeast Mouse Worm Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.040
|
Yeast Mouse Worm Fly |
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.040
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.039
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.039
|
Fly |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.039
|
|
|
|
intermediate filament based process
|
GO:0045103 |
27 |
0.038
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.038
|
Yeast Mouse Worm Fly |
|
|
regulation of rap gtpase activity
|
GO:0032317 |
6 |
0.038
|
Worm |
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
3 |
0.038
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.037
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.037
|
Yeast |
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.037
|
Yeast |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.037
|
Yeast Mouse Worm Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.037
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.037
|
|
|
|
terminal button organization
|
GO:0072553 |
3 |
0.037
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.037
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
10 |
0.036
|
Yeast |
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.036
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.036
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.036
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.036
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.036
|
Fly |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.035
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.035
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.035
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.034
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.034
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.034
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.034
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.034
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.034
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.034
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.034
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.034
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.033
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.033
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.033
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.033
|
|
|
|
positive regulation of monooxygenase activity
|
GO:0032770 |
2 |
0.033
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.033
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.033
|
Yeast |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.033
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.032
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.032
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.032
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.032
|
Yeast Mouse Worm Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.032
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.032
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.032
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.032
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.032
|
Yeast |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.032
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.031
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.031
|
Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.031
|
Yeast Mouse Worm Fly |
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.031
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.031
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.031
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.030
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.030
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.030
|
|
|
|
translation
|
GO:0006412 |
93 |
0.030
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.030
|
|
|
|
regulation of substrate adhesion dependent cell spreading
|
GO:1900024 |
12 |
0.030
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.029
|
Yeast Fly |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.029
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.029
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.029
|
Mouse |
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.029
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.029
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.028
|
Yeast Mouse Worm Fly |
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
32 |
0.028
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.028
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.028
|
Fly |
|
|
sensory perception
|
GO:0007600 |
245 |
0.028
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.028
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.028
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.028
|
Fly |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.028
|
Yeast Mouse Worm Fly |
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.027
|
Yeast |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.027
|
Mouse |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.027
|
Fly |
|
|
positive regulation of dendrite development
|
GO:1900006 |
21 |
0.027
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.027
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.027
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.027
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.027
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.027
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.027
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.027
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
143 |
0.027
|
Fly |
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.027
|
Yeast |
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.027
|
Fly |
|
|
organelle localization
|
GO:0051640 |
179 |
0.027
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.026
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.026
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.026
|
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.026
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.026
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.026
|
|
|
|
gonad morphogenesis
|
GO:0035262 |
1 |
0.026
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.026
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.025
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.025
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.025
|
Yeast Fly |
|
|
barbed end actin filament capping
|
GO:0051016 |
6 |
0.025
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.025
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.025
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.025
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.025
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.024
|
Yeast |
|
|
regulation of translation
|
GO:0006417 |
71 |
0.024
|
|
|
|
secretory granule organization
|
GO:0033363 |
20 |
0.024
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.024
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.024
|
|
|
|
learning
|
GO:0007612 |
98 |
0.024
|
Mouse |
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.024
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.024
|
|
|
|
phospholipid biosynthetic process
|
GO:0008654 |
36 |
0.024
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.024
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.023
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.023
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.023
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.023
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.023
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.023
|
Yeast |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.023
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.023
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.023
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.023
|
Yeast Mouse Worm Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.023
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.022
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.022
|
Mouse |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.022
|
Yeast |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.022
|
Mouse Worm |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.022
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.022
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.022
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.022
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.022
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.022
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.022
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.022
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.022
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.022
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.022
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.021
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.021
|
Yeast |
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.021
|
Yeast |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.021
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.021
|
Worm |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.021
|
Yeast Mouse Worm Fly |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.021
|
Yeast |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.021
|
|
|
|
formation of organ boundary
|
GO:0010160 |
1 |
0.021
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.021
|
Yeast Worm |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.021
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.021
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.021
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.021
|
Yeast Worm |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.021
|
|
|
|
negative regulation of fibroblast apoptotic process
|
GO:2000270 |
6 |
0.020
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.020
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.020
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.020
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.020
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
245 |
0.020
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.020
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.020
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.020
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.020
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.019
|
Worm |
|
|
negative regulation of synaptic vesicle exocytosis
|
GO:2000301 |
3 |
0.019
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.019
|
Worm |
|
|
protein localization to chromosome centromeric region
|
GO:0071459 |
1 |
0.019
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.019
|
Fly |
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.019
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.019
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.019
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.019
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.019
|
Worm |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.018
|
Yeast Mouse Worm Fly |
|
|
urogenital system development
|
GO:0001655 |
261 |
0.018
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.018
|
|
|
|
negative regulation of actin filament depolymerization
|
GO:0030835 |
9 |
0.018
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.018
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.018
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.018
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.018
|
Yeast Fly |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.018
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.018
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.018
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.018
|
|
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
40 |
0.018
|
|
|
|
actin filament depolymerization
|
GO:0030042 |
15 |
0.018
|
|
|
|
positive regulation of nitric oxide synthase activity
|
GO:0051000 |
2 |
0.018
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.018
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.018
|
Yeast |
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.018
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.018
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.017
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.017
|
Fly |
|
|
negative regulation of synaptic vesicle transport
|
GO:1902804 |
3 |
0.017
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.017
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.017
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.017
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.017
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.017
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.017
|
Yeast |
|
|
germ cell development
|
GO:0007281 |
185 |
0.017
|
Worm Fly |
|
|
spindle localization
|
GO:0051653 |
22 |
0.017
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
3 |
0.017
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.017
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.016
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.016
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.016
|
Fly |
|
|
gastrulation
|
GO:0007369 |
116 |
0.016
|
Fly |
|
|
t cell activation
|
GO:0042110 |
289 |
0.016
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.016
|
|
|
|
positive regulation of lyase activity
|
GO:0051349 |
11 |
0.016
|
Yeast |
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
3 |
0.016
|
Worm |
|
|
dna methylation
|
GO:0006306 |
43 |
0.016
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.016
|
Worm Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.016
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.016
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.016
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.016
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.016
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.016
|
|
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.016
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.016
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.016
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.016
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.016
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.016
|
Fly |
|
|
heart contraction
|
GO:0060047 |
93 |
0.016
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.016
|
Mouse |
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.015
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.015
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.015
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.015
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.015
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.015
|
Worm |
|
|
synapse organization
|
GO:0050808 |
125 |
0.015
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.015
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.015
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.015
|
Fly |
|
|
establishment of endothelial blood brain barrier
|
GO:0014045 |
3 |
0.015
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.015
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.015
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.015
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.015
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.015
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.015
|
Yeast |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.015
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.015
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.015
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.015
|
Yeast Mouse Worm Fly |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.015
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.015
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.015
|
Worm |
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
3 |
0.015
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.014
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.014
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.014
|
Yeast Worm |
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.014
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.014
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.014
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.014
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.014
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.014
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.014
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.014
|
Mouse |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.014
|
|
|
|
ventricular cardiac muscle tissue morphogenesis
|
GO:0055010 |
32 |
0.014
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.014
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.014
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.014
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.014
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.014
|
Yeast |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.014
|
Worm |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.014
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.014
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.014
|
|
|
|
positive regulation of synapse assembly
|
GO:0051965 |
18 |
0.014
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.014
|
Mouse |
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.013
|
|
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.013
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.013
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.013
|
Mouse |
|
|
rna splicing
|
GO:0008380 |
54 |
0.013
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.013
|
|
|
|
regulation of rac protein signal transduction
|
GO:0035020 |
19 |
0.013
|
Mouse |
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.013
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.013
|
|
|
|
acrosome assembly
|
GO:0001675 |
11 |
0.013
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.013
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.013
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
1 |
0.013
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.013
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.013
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.013
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.013
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.013
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.013
|
Yeast |
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.013
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.013
|
Yeast Fly |
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.013
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.013
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.013
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.013
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.013
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.013
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.013
|
Mouse |
|
|
protein processing
|
GO:0016485 |
163 |
0.013
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.013
|
Yeast |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.013
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.013
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.013
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.013
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
51 |
0.013
|
|
|
|
cell fate determination involved in pattern specification
|
GO:0060582 |
1 |
0.013
|
|
|
|
response to mineralocorticoid
|
GO:0051385 |
1 |
0.013
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.013
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.012
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.012
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.012
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.012
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.012
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.012
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.012
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.012
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.012
|
Fly |
|
|
renal system development
|
GO:0072001 |
225 |
0.012
|
Fly |
|
|
protein maturation
|
GO:0051604 |
176 |
0.012
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.012
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.012
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.012
|
Fly |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.012
|
|
|
|
positive regulation of filopodium assembly
|
GO:0051491 |
10 |
0.012
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.012
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.012
|
|
