Mus musculus

172 known processes

Nrg1

neuregulin 1

(Aliases: GGFII,SMDF,ARIA,NDF,Hgl,GGF,6030402G23Rik,HRGalpha,HRG,D230005F13Rik)

Nrg1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lateral line nerve development GO:0048892 1 0.997
dendrite extension GO:0097484 3 0.996
axon target recognition GO:0007412 4 0.988
positive regulation of neuron maturation GO:0014042 2 0.978
axon guidance GO:0007411 141 0.928
neuron projection guidance GO:0097485 141 0.890
stem cell fate determination GO:0048867 2 0.884
positive regulation of cellular amine metabolic process GO:0033240 5 0.864
schwann cell development GO:0014044 22 0.853
regulation of cellular amino acid metabolic process GO:0006521 5 0.842
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.837
hindbrain tangential cell migration GO:0021934 2 0.831
nerve growth factor signaling pathway GO:0038180 3 0.827
axonogenesis GO:0007409 274 0.789
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.767
peripheral nervous system development GO:0007422 53 0.735
gamma aminobutyric acid signaling pathway GO:0007214 8 0.721
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.718
positive regulation of axon extension GO:0045773 20 0.702
cellular amine metabolic process GO:0044106 44 0.696
positive regulation of neuron projection regeneration GO:0070572 2 0.693
chemotaxis GO:0006935 247 0.673
neuron projection extension GO:1990138 64 0.664
positive regulation of neuron differentiation GO:0045666 141 0.649
autonomic nervous system development GO:0048483 43 0.645
positive regulation of protein phosphorylation GO:0001934 242 0.623
developmental growth involved in morphogenesis GO:0060560 138 0.612
kidney development GO:0001822 213 0.603
motor neuron axon guidance GO:0008045 26 0.598
schwann cell differentiation GO:0014037 26 0.594
rho protein signal transduction GO:0007266 32 0.579
forebrain development GO:0030900 302 0.557
kidney epithelium development GO:0072073 121 0.557
central nervous system morphogenesis GO:0021551 2 0.555
glial cell fate determination GO:0007403 3 0.548
lateral line system development GO:0048925 1 0.548
sequestering of metal ion GO:0051238 19 0.546
embryonic genitalia morphogenesis GO:0030538 4 0.545
negative regulation of synaptic transmission gabaergic GO:0032229 2 0.541
olfactory learning GO:0008355 2 0.540
stem cell fate commitment GO:0048865 5 0.529
cellular ketone metabolic process GO:0042180 84 0.523
regulation of membrane potential GO:0042391 192 0.520
Rat
organic acid transport GO:0015849 101 0.498
cellular response to growth factor stimulus GO:0071363 197 0.497
oocyte axis specification GO:0007309 2 0.489
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.484
regulation of axon extension GO:0030516 43 0.483
glial cell differentiation GO:0010001 131 0.473
cerebral cortex development GO:0021987 86 0.473
brain derived neurotrophic factor receptor signaling pathway GO:0031547 3 0.466
ear development GO:0043583 200 0.455
enteric nervous system development GO:0048484 11 0.449
positive regulation of nervous system development GO:0051962 221 0.446
oculomotor nerve morphogenesis GO:0021622 2 0.444
neurotrophin signaling pathway GO:0038179 12 0.444
peripheral nervous system neuron axonogenesis GO:0048936 3 0.439
metencephalon development GO:0022037 89 0.438
Zebrafish
regulation of neuron differentiation GO:0045664 281 0.429
regulation of synaptic transmission gabaergic GO:0032228 17 0.425
regulation of cell size GO:0008361 72 0.416
gliogenesis GO:0042063 141 0.415
negative regulation of cell proliferation GO:0008285 296 0.410
cellular response to nerve growth factor stimulus GO:1990090 3 0.401
ras protein signal transduction GO:0007265 77 0.400
dendrite development GO:0016358 115 0.392
nerve development GO:0021675 67 0.391
circadian rhythm GO:0007623 114 0.390
positive regulation of cell maturation GO:1903431 4 0.388
formation of organ boundary GO:0010160 1 0.387
pons development GO:0021548 13 0.385
mapk cascade GO:0000165 281 0.383
response to nerve growth factor GO:1990089 3 0.383
regulation of neuron projection development GO:0010975 169 0.376
regulation of rho gtpase activity GO:0032319 58 0.372
g protein coupled receptor signaling pathway GO:0007186 243 0.366
regulation of extent of cell growth GO:0061387 52 0.365
cerebral cortex cell migration GO:0021795 44 0.358
cranial nerve development GO:0021545 41 0.354
calcium ion transport into cytosol GO:0060402 48 0.353
medulla oblongata development GO:0021550 3 0.348
telencephalon cell migration GO:0022029 55 0.347
positive regulation of cell development GO:0010720 237 0.345
regulation of cellular amine metabolic process GO:0033238 20 0.342
retinal cell programmed cell death GO:0046666 8 0.338
regulation of cell growth GO:0001558 91 0.335
Human
fibroblast proliferation GO:0048144 35 0.327
cellular response to amino acid stimulus GO:0071230 29 0.323
cellular response to acid chemical GO:0071229 68 0.321
ensheathment of neurons GO:0007272 76 0.319
Rat
tongue development GO:0043586 18 0.316
innervation GO:0060384 22 0.315
negative regulation of neuron apoptotic process GO:0043524 92 0.315
small gtpase mediated signal transduction GO:0007264 97 0.314
myelination GO:0042552 74 0.313
Rat
oocyte construction GO:0007308 2 0.312
developmental cell growth GO:0048588 84 0.312
response to retinoic acid GO:0032526 56 0.310
establishment of neuroblast polarity GO:0045200 1 0.309
pallium development GO:0021543 120 0.304
rhombomere 5 development GO:0021571 4 0.299
neuron neuron synaptic transmission GO:0007270 69 0.299
response to growth factor GO:0070848 198 0.297
t cell proliferation GO:0042098 120 0.297
forebrain generation of neurons GO:0021872 63 0.291
olfactory lobe development GO:0021988 32 0.291
forebrain cell migration GO:0021885 58 0.289
axon regeneration GO:0031103 12 0.281
sensory system development GO:0048880 3 0.276
multicellular organismal response to stress GO:0033555 62 0.276
forebrain neuron differentiation GO:0021879 52 0.272
cation transport GO:0006812 399 0.272
positive regulation of protein modification process GO:0031401 299 0.271
cell fate commitment GO:0045165 210 0.270
olfactory bulb interneuron differentiation GO:0021889 12 0.270
telencephalon development GO:0021537 186 0.264
learning or memory GO:0007611 148 0.262
sensory organ morphogenesis GO:0090596 242 0.261
detection of external stimulus GO:0009581 61 0.256
stem cell maintenance GO:0019827 130 0.250
extrinsic apoptotic signaling pathway GO:0097191 126 0.248
Human
stem cell proliferation GO:0072089 117 0.247
positive regulation of gtp catabolic process GO:0033126 85 0.242
regulation of rho protein signal transduction GO:0035023 71 0.241
rhombomere morphogenesis GO:0021593 2 0.241
peptidyl amino acid modification GO:0018193 336 0.239
Human
olfactory bulb development GO:0021772 30 0.237
stem cell differentiation GO:0048863 268 0.237
Human Zebrafish
trochlear nerve development GO:0021558 3 0.236
neuron apoptotic process GO:0051402 142 0.236
regulation of neuron apoptotic process GO:0043523 122 0.232
peptidyl tyrosine modification GO:0018212 145 0.232
Human
apoptotic signaling pathway GO:0097190 306 0.227
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.226
carboxylic acid transport GO:0046942 100 0.223
negative regulation of anoikis GO:2000811 2 0.221
ventral spinal cord development GO:0021517 48 0.219
amino acid transport GO:0006865 61 0.215
cognition GO:0050890 149 0.215
t cell activation GO:0042110 289 0.214
anion transport GO:0006820 177 0.209
positive regulation of growth GO:0045927 104 0.209
Human
axon ensheathment GO:0008366 76 0.208
Rat
positive regulation of ras gtpase activity GO:0032320 65 0.207
negative regulation of nervous system development GO:0051961 156 0.205
mechanoreceptor differentiation GO:0042490 67 0.196
regulation of cell activation GO:0050865 289 0.195
erbb signaling pathway GO:0038127 32 0.192
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.192
asymmetric neuroblast division GO:0055059 1 0.191
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.188
cell growth GO:0016049 130 0.187
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.186
negative regulation of apoptotic signaling pathway GO:2001234 104 0.186
Human
neuron death GO:0070997 154 0.185
gonad development GO:0008406 141 0.185
nephron epithelium morphogenesis GO:0072088 68 0.185
regulation of homeostatic process GO:0032844 182 0.180
development of primary sexual characteristics GO:0045137 143 0.177
regulation of stat protein import into nucleus GO:2000364 2 0.177
neuron recognition GO:0008038 25 0.176
negative regulation of cell activation GO:0050866 111 0.176
regulation of ion homeostasis GO:2000021 64 0.174
stem cell development GO:0048864 219 0.172
Zebrafish
response to acid chemical GO:0001101 111 0.171
cellular lipid metabolic process GO:0044255 323 0.171
camera type eye development GO:0043010 266 0.170
guanosine containing compound catabolic process GO:1901069 144 0.170
bmp signaling pathway GO:0030509 93 0.170
positive regulation of neuron projection development GO:0010976 79 0.168
lymphocyte differentiation GO:0030098 242 0.168
interspecies interaction between organisms GO:0044419 83 0.166
regulation of cell projection organization GO:0031344 206 0.164
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.164
ureteric bud development GO:0001657 94 0.163
positive regulation of cell projection organization GO:0031346 95 0.162
organic anion transport GO:0015711 137 0.162
glutamate secretion GO:0014047 8 0.161
cell type specific apoptotic process GO:0097285 268 0.160
Human
peptidyl serine phosphorylation GO:0018105 74 0.160
dicarboxylic acid transport GO:0006835 29 0.158
t cell differentiation in thymus GO:0033077 77 0.157
positive regulation of protein kinase activity GO:0045860 144 0.157
sequestering of calcium ion GO:0051208 18 0.155
rhythmic process GO:0048511 174 0.154
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.154
locus ceruleus development GO:0021703 1 0.153
neuron maturation GO:0042551 29 0.151
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.150
Human
circulatory system process GO:0003013 197 0.149
Rat
regulation of fibroblast proliferation GO:0048145 34 0.149
intracellular receptor signaling pathway GO:0030522 74 0.147
prenylation GO:0097354 3 0.146
oligodendrocyte differentiation GO:0048709 53 0.145
Zebrafish
nucleoside catabolic process GO:0009164 206 0.145
cellular nitrogen compound catabolic process GO:0044270 280 0.145
regulation of nucleoside metabolic process GO:0009118 130 0.144
positive regulation of mapk cascade GO:0043410 170 0.143
parasympathetic nervous system development GO:0048486 19 0.142
negative regulation of homeostatic process GO:0032845 71 0.142
negative regulation of immature t cell proliferation GO:0033087 3 0.141
regulation of gtp catabolic process GO:0033124 113 0.141
embryonic organ morphogenesis GO:0048562 276 0.139
glial cell development GO:0021782 54 0.139
neuromuscular synaptic transmission GO:0007274 16 0.139
oculomotor nerve development GO:0021557 4 0.137
regulation of ras gtpase activity GO:0032318 88 0.137
glial cell fate commitment GO:0021781 14 0.137
regulation of kinase activity GO:0043549 249 0.137
action potential GO:0001508 78 0.135
Rat
oocyte development GO:0048599 33 0.134
regulation of leukocyte differentiation GO:1902105 159 0.133
regionalization GO:0003002 337 0.133
regulation of cytoplasmic transport GO:1903649 112 0.133
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.131
regulation of wnt signaling pathway GO:0030111 123 0.131
cytoplasmic transport GO:0016482 234 0.130
establishment or maintenance of neuroblast polarity GO:0045196 1 0.130
protein autophosphorylation GO:0046777 61 0.129
eye photoreceptor cell differentiation GO:0001754 41 0.129
formation of anatomical boundary GO:0048859 6 0.129
regulation of erk1 and erk2 cascade GO:0070372 71 0.127
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.126
muscle cell proliferation GO:0033002 52 0.126
Human
regulation of ras protein signal transduction GO:0046578 114 0.125
striated muscle tissue development GO:0014706 293 0.124
trigeminal nerve development GO:0021559 10 0.123
regulation of stem cell proliferation GO:0072091 78 0.123
cardiac muscle cell proliferation GO:0060038 31 0.122
Human
regulation of establishment of protein localization GO:0070201 181 0.122
negative regulation of neuron differentiation GO:0045665 101 0.121
regulation of anoikis GO:2000209 2 0.121
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 6 0.121
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.121
acid secretion GO:0046717 33 0.120
neuromuscular process GO:0050905 99 0.120
regulation of neuron maturation GO:0014041 5 0.120
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.118
Human
leukocyte differentiation GO:0002521 342 0.118
mesoderm formation GO:0001707 62 0.118
transmission of nerve impulse GO:0019226 76 0.117
Rat
rhombomere 3 morphogenesis GO:0021658 2 0.117
response to steroid hormone GO:0048545 56 0.117
sympathetic nervous system development GO:0048485 22 0.116
central nervous system neuron differentiation GO:0021953 162 0.116
Zebrafish
segmentation GO:0035282 93 0.116
appendage morphogenesis GO:0035107 149 0.115
regulation of intracellular transport GO:0032386 159 0.115
central nervous system neuron development GO:0021954 67 0.115
oocyte differentiation GO:0009994 35 0.115
digestive system development GO:0055123 200 0.114
rac protein signal transduction GO:0016601 13 0.114
negative regulation of neuron death GO:1901215 98 0.114
ion transmembrane transport GO:0034220 361 0.113
cellular response to organonitrogen compound GO:0071417 145 0.113
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.113
respiratory system development GO:0060541 190 0.112
peptidyl serine modification GO:0018209 83 0.112
leukocyte proliferation GO:0070661 172 0.112
response to amino acid GO:0043200 37 0.112
jak stat cascade GO:0007259 42 0.112
cardiac muscle tissue regeneration GO:0061026 1 0.111
renal system development GO:0072001 225 0.111
neuron migration GO:0001764 122 0.110
central nervous system segmentation GO:0035283 3 0.109
response to drug GO:0042493 75 0.109
negative regulation of phosphorylation GO:0042326 166 0.107
regulation of cellular component size GO:0032535 121 0.105
glucose import GO:0046323 32 0.105
cellular response to lipid GO:0071396 145 0.104
positive regulation of rho gtpase activity GO:0032321 41 0.104
sensory organ boundary specification GO:0008052 1 0.104
negative regulation of neuroblast proliferation GO:0007406 7 0.104
connective tissue development GO:0061448 179 0.104
purine nucleoside triphosphate metabolic process GO:0009144 226 0.104
maintenance of location GO:0051235 89 0.103
regulation of purine nucleotide catabolic process GO:0033121 122 0.102
g1 s transition of mitotic cell cycle GO:0000082 57 0.102
negative regulation of lymphocyte proliferation GO:0050672 45 0.102
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.101
Human
positive regulation of fibroblast proliferation GO:0048146 20 0.101
regulation of cell motility GO:2000145 236 0.101
myelination in peripheral nervous system GO:0022011 19 0.101
regulation of retinal cell programmed cell death GO:0046668 5 0.101
noradrenergic neuron differentiation GO:0003357 6 0.101
lymphocyte proliferation GO:0046651 164 0.100
smoothened signaling pathway GO:0007224 105 0.100
cytokine production GO:0001816 319 0.100
germ cell development GO:0007281 185 0.099
noradrenergic neuron development GO:0003358 3 0.099
ureteric bud morphogenesis GO:0060675 62 0.099
cell differentiation in hindbrain GO:0021533 24 0.098
Zebrafish
adult behavior GO:0030534 135 0.098
skeletal system morphogenesis GO:0048705 203 0.097
muscle cell differentiation GO:0042692 261 0.097
positive regulation of glucose import GO:0046326 14 0.097
regulation of glucose transport GO:0010827 32 0.097
tyrosine phosphorylation of stat protein GO:0007260 23 0.096
nitrogen compound transport GO:0071705 271 0.094
regulation of cell migration GO:0030334 219 0.094
ameboidal type cell migration GO:0001667 128 0.094
Zebrafish
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.094
regulation of t cell differentiation in thymus GO:0033081 24 0.093
neuron projection regeneration GO:0031102 14 0.093
compound eye development GO:0048749 1 0.093
erk1 and erk2 cascade GO:0070371 77 0.093
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.093
cartilage development GO:0051216 140 0.093
positive regulation of stat protein import into nucleus GO:2000366 2 0.092
taste bud development GO:0061193 2 0.092
cell maturation GO:0048469 127 0.091
mesenchyme development GO:0060485 152 0.091
Zebrafish
axonal fasciculation GO:0007413 15 0.091
single organismal cell cell adhesion GO:0016337 131 0.090
appendage development GO:0048736 166 0.088
negative regulation of secretion GO:0051048 61 0.088
Human
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.088
negative regulation of cell cycle GO:0045786 123 0.088
purine containing compound metabolic process GO:0072521 311 0.088
neurotransmitter transport GO:0006836 76 0.087
digestive tract morphogenesis GO:0048546 147 0.087
inner ear morphogenesis GO:0042472 101 0.087
regulation of t cell proliferation GO:0042129 92 0.086
negative regulation of wnt signaling pathway GO:0030178 73 0.086
regulation of mapk cascade GO:0043408 248 0.086
rhombomere 3 development GO:0021569 4 0.086
neuroblast differentiation GO:0014016 2 0.085
sensory perception GO:0007600 245 0.085
amine metabolic process GO:0009308 45 0.085
negative regulation of leukocyte differentiation GO:1902106 51 0.085
negative regulation of t cell proliferation GO:0042130 38 0.085
skeletal muscle cell differentiation GO:0035914 66 0.084
developmental maturation GO:0021700 193 0.084
positive regulation of bmp signaling pathway GO:0030513 23 0.084
hindbrain development GO:0030902 128 0.083
Zebrafish
sertoli cell development GO:0060009 15 0.083
wnt signaling pathway GO:0016055 188 0.083
transmembrane transport GO:0055085 412 0.082
cellular metal ion homeostasis GO:0006875 151 0.082
detection of stimulus GO:0051606 84 0.082
neuroblast proliferation GO:0007405 49 0.082
spinal cord motor neuron differentiation GO:0021522 35 0.081
learning GO:0007612 98 0.081
single organism cell adhesion GO:0098602 156 0.081
cranial nerve formation GO:0021603 4 0.080
central nervous system neuron axonogenesis GO:0021955 28 0.079
regulation of t cell differentiation GO:0045580 83 0.079
genitalia development GO:0048806 37 0.079
motor neuron migration GO:0097475 4 0.079
cell migration in hindbrain GO:0021535 16 0.079
positive regulation of hydrolase activity GO:0051345 148 0.078
signal transduction in absence of ligand GO:0038034 55 0.078
Human
sertoli cell differentiation GO:0060008 18 0.077
brain segmentation GO:0035284 3 0.077
cytosolic calcium ion transport GO:0060401 48 0.077
cellular ion homeostasis GO:0006873 165 0.076
regulation of map kinase activity GO:0043405 120 0.076
regulation of glial cell differentiation GO:0045685 41 0.075
striated muscle cell proliferation GO:0014855 39 0.075
Human
female gonad development GO:0008585 71 0.075
regulation of apoptotic signaling pathway GO:2001233 197 0.075
Human
palate development GO:0060021 76 0.075
ribonucleoside catabolic process GO:0042454 206 0.074
rhombomere formation GO:0021594 1 0.074
embryonic placenta development GO:0001892 98 0.074
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.073
regulation of glucose import GO:0046324 26 0.073
calcium ion transport GO:0006816 159 0.073
protein prenylation GO:0018342 3 0.073
regulation of postsynaptic membrane potential GO:0060078 48 0.073
positive regulation of programmed cell death GO:0043068 218 0.073
associative learning GO:0008306 61 0.073
positive regulation of glucose transport GO:0010828 16 0.072
mesonephric epithelium development GO:0072163 94 0.072
positive regulation of nucleoside metabolic process GO:0045979 91 0.072
divalent inorganic cation homeostasis GO:0072507 138 0.071
jnk cascade GO:0007254 72 0.071
immature t cell proliferation GO:0033079 8 0.070
regulation of protein serine threonine kinase activity GO:0071900 157 0.070
hindbrain morphogenesis GO:0021575 46 0.069
Zebrafish
cellular response to retinoic acid GO:0071300 25 0.069
positive regulation of cellular catabolic process GO:0031331 148 0.068
negative regulation of lymphocyte activation GO:0051250 91 0.068
synaptic transmission GO:0007268 329 0.068
positive regulation of cell migration GO:0030335 109 0.068
hepaticobiliary system development GO:0061008 67 0.068
divalent metal ion transport GO:0070838 172 0.068
regulation of smoothened signaling pathway GO:0008589 58 0.067
mesenchymal cell development GO:0014031 93 0.067
Zebrafish
organophosphate catabolic process GO:0046434 232 0.067
regulation of cell maturation GO:1903429 13 0.067
neurotransmitter secretion GO:0007269 62 0.067
divalent inorganic cation transport GO:0072511 178 0.067
response to organic cyclic compound GO:0014070 198 0.067
regulation of gliogenesis GO:0014013 50 0.067
purine nucleoside catabolic process GO:0006152 205 0.067
cell adhesion GO:0007155 329 0.066
Human
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.065
regulation of cellular catabolic process GO:0031329 242 0.065
guanosine containing compound metabolic process GO:1901068 144 0.065
response to alcohol GO:0097305 48 0.065
multicellular organismal signaling GO:0035637 91 0.065
Rat
b cell activation GO:0042113 161 0.065
mammary gland lobule development GO:0061377 22 0.065
cytosolic calcium ion homeostasis GO:0051480 70 0.064
positive regulation of heart growth GO:0060421 18 0.064
Human
mesonephric tubule development GO:0072164 94 0.064
positive regulation of cell growth GO:0030307 33 0.064
Human
positive regulation of cell death GO:0010942 224 0.063
hematopoietic progenitor cell differentiation GO:0002244 143 0.063
negative regulation of leukocyte proliferation GO:0070664 46 0.062
spinal cord motor neuron migration GO:0097476 4 0.062
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.062
Human
tissue remodeling GO:0048771 102 0.062
negative regulation of cell cycle process GO:0010948 69 0.062
limb development GO:0060173 166 0.062
pituitary gland development GO:0021983 38 0.062
purine nucleotide catabolic process GO:0006195 211 0.062
negative regulation of mitotic cell cycle GO:0045930 58 0.061
detection of chemical stimulus GO:0009593 16 0.061
regulation of canonical wnt signaling pathway GO:0060828 82 0.061
transcription from rna polymerase i promoter GO:0006360 13 0.061
regulation of organ morphogenesis GO:2000027 144 0.061
membrane organization GO:0061024 245 0.061
anatomical structure homeostasis GO:0060249 145 0.061
peripheral nervous system neuron development GO:0048935 9 0.060
positive regulation of hormone secretion GO:0046887 38 0.060
positive regulation of ras protein signal transduction GO:0046579 13 0.060
purine ribonucleotide catabolic process GO:0009154 208 0.060
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.060
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.060
visceral motor neuron differentiation GO:0021524 3 0.060
limbic system development GO:0021761 72 0.060
male sex differentiation GO:0046661 109 0.060
positive regulation of map kinase activity GO:0043406 84 0.059
digestive tract development GO:0048565 190 0.059
nucleoside metabolic process GO:0009116 246 0.059
regulation of neuron death GO:1901214 134 0.059
negative regulation of t cell activation GO:0050868 65 0.059
fear response GO:0042596 33 0.059
regulation of t cell activation GO:0050863 170 0.059
stress activated protein kinase signaling cascade GO:0031098 81 0.059
embryonic limb morphogenesis GO:0030326 126 0.059
sensory perception of pain GO:0019233 47 0.059
regulation of anatomical structure size GO:0090066 178 0.058
establishment or maintenance of cell polarity GO:0007163 86 0.058
positive regulation of insulin secretion GO:0032024 26 0.058
regulation of interleukin 1 alpha production GO:0032650 4 0.058
regulation of respiratory system process GO:0044065 13 0.058
regulation of nucleotide catabolic process GO:0030811 122 0.058
spinal cord development GO:0021510 81 0.058
activation of immune response GO:0002253 138 0.057
release of sequestered calcium ion into cytosol GO:0051209 42 0.056
nucleoside phosphate metabolic process GO:0006753 338 0.056
cellular response to insulin stimulus GO:0032869 78 0.055
regulation of purine nucleotide metabolic process GO:1900542 169 0.055
cellular divalent inorganic cation homeostasis GO:0072503 127 0.055
urogenital system development GO:0001655 261 0.055
male gamete generation GO:0048232 285 0.055
metanephros development GO:0001656 79 0.054
nucleoside triphosphate catabolic process GO:0009143 205 0.054
long term memory GO:0007616 15 0.054
gtp catabolic process GO:0006184 143 0.054
ribonucleoside metabolic process GO:0009119 245 0.054
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.054
oogenesis GO:0048477 56 0.054
diencephalon development GO:0021536 63 0.053
neuron fate specification GO:0048665 30 0.053
regulation of secretion GO:0051046 274 0.053
Human
negative regulation of immune system process GO:0002683 209 0.053
regulation of response to wounding GO:1903034 189 0.052
cardiac muscle tissue growth GO:0055017 37 0.052
Human
regulation of protein kinase b signaling GO:0051896 56 0.052
purine nucleotide metabolic process GO:0006163 302 0.052
cell recognition GO:0008037 83 0.052
transcription from rna polymerase iii promoter GO:0006383 3 0.052
carbohydrate metabolic process GO:0005975 230 0.052
regulation of lymphocyte differentiation GO:0045619 107 0.051
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.051
lateral motor column neuron migration GO:0097477 3 0.051
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 8 0.051
protein catabolic process GO:0030163 221 0.051
regulation of mitotic cell cycle phase transition GO:1901990 73 0.051
retinal rod cell development GO:0046548 10 0.050

Nrg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.337
disease of cellular proliferation DOID:14566 0 0.337
organ system cancer DOID:0050686 0 0.337
disease of anatomical entity DOID:7 0 0.291
nervous system disease DOID:863 0 0.291
sensory system disease DOID:0050155 0 0.122
eye and adnexa disease DOID:1492 0 0.122
immune system cancer DOID:0060083 0 0.116
hematologic cancer DOID:2531 0 0.116
neuropathy DOID:870 0 0.074
retinal disease DOID:5679 0 0.066
retinal degeneration DOID:8466 0 0.066
eye disease DOID:5614 0 0.066
neuromuscular disease DOID:440 0 0.055