Mus musculus

0 known processes

Nsfl1c

NSFL1 (p97) cofactor (p47)

(Aliases: p47,MGC86097,Stxbp3a,MGC61403,Munc-18c)

Nsfl1c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to misfolded protein GO:0071218 5 0.592
organelle membrane fusion GO:0090174 1 0.588
cellular response to cadmium ion GO:0071276 3 0.539
translesion synthesis GO:0019985 1 0.444
inclusion body assembly GO:0070841 3 0.328
response to misfolded protein GO:0051788 5 0.266
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.238
cellular protein catabolic process GO:0044257 155 0.234
regulation of protein deubiquitination GO:0090085 1 0.211
modification dependent macromolecule catabolic process GO:0043632 133 0.204
peptidyl amino acid modification GO:0018193 336 0.203
cellular macromolecule catabolic process GO:0044265 206 0.167
macromolecule glycosylation GO:0043413 55 0.167
regulation of chromatin modification GO:1903308 57 0.151
metaphase plate congression GO:0051310 2 0.151
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.150
purine ribonucleotide metabolic process GO:0009150 290 0.147
ribonucleoside metabolic process GO:0009119 245 0.143
purine nucleotide metabolic process GO:0006163 302 0.143
covalent chromatin modification GO:0016569 163 0.139
protein glycosylation GO:0006486 55 0.135
membrane fusion GO:0061025 38 0.132
Rat
organelle disassembly GO:1903008 2 0.130
cellular response to dna damage stimulus GO:0006974 207 0.130
regulation of organelle organization GO:0033043 289 0.116
purine ribonucleoside catabolic process GO:0046130 205 0.110
chromatin modification GO:0016568 187 0.109
histone modification GO:0016570 159 0.104
protein catabolic process GO:0030163 221 0.096
Mouse
positive regulation of protein modification process GO:0031401 299 0.095
proteasomal protein catabolic process GO:0010498 98 0.095
purine containing compound metabolic process GO:0072521 311 0.093
regulation of cellular catabolic process GO:0031329 242 0.093
macromolecule catabolic process GO:0009057 281 0.092
Mouse
membrane organization GO:0061024 245 0.091
Rat
ribonucleotide metabolic process GO:0009259 291 0.091
nucleoside phosphate metabolic process GO:0006753 338 0.090
nucleoside metabolic process GO:0009116 246 0.087
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.087
ribose phosphate metabolic process GO:0019693 291 0.086
modification dependent protein catabolic process GO:0019941 133 0.083
ubiquitin dependent protein catabolic process GO:0006511 129 0.080
nucleotide catabolic process GO:0009166 217 0.079
chromatin organization GO:0006325 206 0.078
ribonucleoside triphosphate catabolic process GO:0009203 199 0.077
positive regulation of hydrolase activity GO:0051345 148 0.076
protein modification by small protein conjugation or removal GO:0070647 207 0.076
Mouse
protein ubiquitination GO:0016567 171 0.074
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.073
nucleoside triphosphate catabolic process GO:0009143 205 0.072
attachment of spindle microtubules to kinetochore GO:0008608 4 0.072
nucleoside triphosphate metabolic process GO:0009141 230 0.071
purine nucleoside triphosphate metabolic process GO:0009144 226 0.071
ribonucleoside triphosphate metabolic process GO:0009199 220 0.071
cellular nitrogen compound catabolic process GO:0044270 280 0.067
heterocycle catabolic process GO:0046700 280 0.067
dna biosynthetic process GO:0071897 22 0.067
glycoprotein biosynthetic process GO:0009101 89 0.066
protein modification by small protein removal GO:0070646 21 0.066
regulation of histone modification GO:0031056 56 0.066
cellular ketone metabolic process GO:0042180 84 0.065
positive regulation of histone modification GO:0031058 28 0.064
positive regulation of organelle organization GO:0010638 128 0.064
purine ribonucleoside metabolic process GO:0046128 241 0.062
nucleobase containing small molecule metabolic process GO:0055086 352 0.062
autophagy GO:0006914 45 0.062
positive regulation of cell death GO:0010942 224 0.062
regulation of hydrolase activity GO:0051336 246 0.062
purine nucleoside metabolic process GO:0042278 241 0.061
nucleotide metabolic process GO:0009117 332 0.060
organelle localization GO:0051640 179 0.060
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.059
cellular amino acid metabolic process GO:0006520 103 0.059
ribonucleoside monophosphate metabolic process GO:0009161 80 0.058
ribonucleoside catabolic process GO:0042454 206 0.057
purine nucleoside triphosphate catabolic process GO:0009146 203 0.056
organophosphate catabolic process GO:0046434 232 0.056
aromatic compound catabolic process GO:0019439 286 0.055
positive regulation of apoptotic process GO:0043065 217 0.054
glycosyl compound metabolic process GO:1901657 246 0.053
organic cyclic compound catabolic process GO:1901361 295 0.053
glycoprotein metabolic process GO:0009100 116 0.052
protein modification by small protein conjugation GO:0032446 187 0.052
Mouse
regulation of chromosome organization GO:0033044 83 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
spermatogenesis GO:0007283 284 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.049
regulation of protein localization GO:0032880 231 0.049
peptidyl asparagine modification GO:0018196 1 0.048
positive regulation of programmed cell death GO:0043068 218 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.048
nucleoside phosphate catabolic process GO:1901292 222 0.048
amine metabolic process GO:0009308 45 0.048
purine nucleotide catabolic process GO:0006195 211 0.047
cytoplasmic transport GO:0016482 234 0.047
rna catabolic process GO:0006401 29 0.046
protein n linked glycosylation GO:0006487 12 0.046
ribonucleotide catabolic process GO:0009261 208 0.045
positive regulation of cellular catabolic process GO:0031331 148 0.045
intracellular mrna localization GO:0008298 4 0.045
carbohydrate derivative catabolic process GO:1901136 231 0.045
atp metabolic process GO:0046034 75 0.044
nucleoside monophosphate metabolic process GO:0009123 85 0.044
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.044
glycosyl compound catabolic process GO:1901658 206 0.043
organonitrogen compound catabolic process GO:1901565 264 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.043
cellular response to topologically incorrect protein GO:0035967 25 0.043
purine ribonucleotide catabolic process GO:0009154 208 0.043
regulation of proteolysis GO:0030162 164 0.043
cellular amine metabolic process GO:0044106 44 0.043
purine containing compound catabolic process GO:0072523 213 0.042
glycosylation GO:0070085 62 0.042
cellular response to nutrient levels GO:0031669 64 0.042
mitotic nuclear division GO:0007067 48 0.041
positive regulation of cellular protein catabolic process GO:1903364 34 0.041
negative regulation of protein metabolic process GO:0051248 282 0.040
nucleoside catabolic process GO:0009164 206 0.040
protein localization to nucleus GO:0034504 121 0.039
gonad development GO:0008406 141 0.039
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.039
multicellular organism growth GO:0035264 161 0.039
protein maturation GO:0051604 176 0.039
nucleoside monophosphate catabolic process GO:0009125 59 0.039
positive regulation of chromatin modification GO:1903310 28 0.039
ribonucleoside monophosphate catabolic process GO:0009158 57 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
positive regulation of endopeptidase activity GO:0010950 43 0.038
protein localization to organelle GO:0033365 185 0.038
maintenance of location GO:0051235 89 0.038
male gamete generation GO:0048232 285 0.037
purine nucleoside monophosphate metabolic process GO:0009126 81 0.037
microtubule based process GO:0007017 236 0.036
meiotic nuclear division GO:0007126 115 0.036
regulation of protein catabolic process GO:0042176 108 0.035
Mouse
aggresome assembly GO:0070842 2 0.035
cellular response to inorganic substance GO:0071241 37 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.035
protein oligomerization GO:0051259 67 0.034
intracellular protein transport GO:0006886 204 0.034
atp catabolic process GO:0006200 55 0.034
cellular protein complex assembly GO:0043623 116 0.033
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.033
establishment of organelle localization GO:0051656 122 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
oocyte anterior posterior axis specification GO:0007314 2 0.033
regulation of cysteine type endopeptidase activity GO:2000116 65 0.032
purine nucleoside catabolic process GO:0006152 205 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
positive regulation of protein complex assembly GO:0031334 45 0.032
regulation of protein complex assembly GO:0043254 83 0.032
nuclear division GO:0000280 158 0.032
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.032
cation transmembrane transport GO:0098655 266 0.031
transmembrane transport GO:0055085 412 0.031
organelle fusion GO:0048284 28 0.031
dna repair GO:0006281 107 0.030
protein deubiquitination GO:0016579 19 0.030
development of primary sexual characteristics GO:0045137 143 0.030
positive regulation of protein ubiquitination GO:0031398 27 0.030
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 14 0.030
apoptotic signaling pathway GO:0097190 306 0.029
mrna metabolic process GO:0016071 84 0.029
response to extracellular stimulus GO:0009991 127 0.029
positive regulation of chromosome organization GO:2001252 33 0.028
positive regulation of cellular component biogenesis GO:0044089 94 0.028
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.027
regulation of protein ubiquitination GO:0031396 52 0.027
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.027
regulation of cell cycle GO:0051726 281 0.027
mitotic sister chromatid segregation GO:0000070 14 0.027
cellular response to extracellular stimulus GO:0031668 81 0.027
cation transport GO:0006812 399 0.026
sister chromatid segregation GO:0000819 20 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
positive regulation of protein catabolic process GO:0045732 60 0.026
cellular response to starvation GO:0009267 57 0.026
positive regulation of growth GO:0045927 104 0.026
mitotic cell cycle GO:0000278 195 0.026
protein complex disassembly GO:0043241 40 0.026
positive regulation of protein phosphorylation GO:0001934 242 0.026
regulation of transferase activity GO:0051338 263 0.026
purine nucleoside monophosphate catabolic process GO:0009128 58 0.025
ion transmembrane transport GO:0034220 361 0.025
protein homooligomerization GO:0051260 43 0.025
regulation of endopeptidase activity GO:0052548 89 0.025
positive regulation of proteolysis GO:0045862 85 0.025
regulation of chromatin organization GO:1902275 57 0.024
double strand break repair GO:0006302 48 0.024
mitotic cell cycle process GO:1903047 159 0.023
response to inorganic substance GO:0010035 96 0.023
response to endoplasmic reticulum stress GO:0034976 53 0.023
cellular response to metal ion GO:0071248 31 0.023
postreplication repair GO:0006301 5 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
regulation of cellular protein catabolic process GO:1903362 61 0.022
cellular response to lipid GO:0071396 145 0.021
oocyte axis specification GO:0007309 2 0.021
mrna processing GO:0006397 63 0.021
methylation GO:0032259 134 0.021
dna metabolic process GO:0006259 303 0.020
protein n linked glycosylation via asparagine GO:0018279 1 0.020
response to organic cyclic compound GO:0014070 198 0.020
maternal determination of anterior posterior axis embryo GO:0008358 2 0.020
response to cadmium ion GO:0046686 8 0.020
organelle fission GO:0048285 170 0.020
response to organonitrogen compound GO:0010243 246 0.020
golgi vesicle transport GO:0048193 30 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
germ cell development GO:0007281 185 0.020
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.019
activation of cysteine type endopeptidase activity GO:0097202 27 0.019
positive regulation of peptidase activity GO:0010952 49 0.019
zymogen activation GO:0031638 41 0.019
oocyte construction GO:0007308 2 0.019
response to light stimulus GO:0009416 135 0.019
cell division GO:0051301 120 0.019
wnt signaling pathway GO:0016055 188 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
regulation of protein kinase activity GO:0045859 232 0.018
cell adhesion GO:0007155 329 0.018
response to metal ion GO:0010038 47 0.018
protein polyubiquitination GO:0000209 33 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.017
macromolecular complex disassembly GO:0032984 43 0.017
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.017
response to nutrient levels GO:0031667 109 0.017
regulation of anatomical structure size GO:0090066 178 0.017
er to golgi vesicle mediated transport GO:0006888 11 0.016
blastocyst development GO:0001824 80 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.016
regulation of proteasomal protein catabolic process GO:0061136 46 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
synaptic transmission GO:0007268 329 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
negative regulation of molecular function GO:0044092 258 0.016
cellular response to external stimulus GO:0071496 88 0.016
myeloid cell differentiation GO:0030099 233 0.015
stem cell differentiation GO:0048863 268 0.015
endoplasmic reticulum unfolded protein response GO:0030968 19 0.015
ras protein signal transduction GO:0007265 77 0.015
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.015
muscle tissue development GO:0060537 308 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.015
response to unfolded protein GO:0006986 21 0.015
regulation of cell motility GO:2000145 236 0.015
regulation of protein maturation GO:1903317 96 0.015
mitotic spindle organization GO:0007052 10 0.014
response to radiation GO:0009314 165 0.014
divalent inorganic cation transport GO:0072511 178 0.014
microtubule anchoring GO:0034453 9 0.014
membrane invagination GO:0010324 17 0.014
protein k63 linked deubiquitination GO:0070536 1 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
regulation of cellular response to stress GO:0080135 159 0.014
developmental maturation GO:0021700 193 0.014
macromolecule methylation GO:0043414 120 0.014
rna splicing GO:0008380 54 0.014
response to starvation GO:0042594 65 0.014
negative regulation of protein modification process GO:0031400 163 0.014
maintenance of location in cell GO:0051651 24 0.014
response to topologically incorrect protein GO:0035966 25 0.014
rna splicing via transesterification reactions GO:0000375 43 0.014
positive regulation of transferase activity GO:0051347 167 0.014
striated muscle tissue development GO:0014706 293 0.013
pole plasm assembly GO:0007315 2 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
rhythmic process GO:0048511 174 0.013
regulation of kinase activity GO:0043549 249 0.013
regulation of cellular component size GO:0032535 121 0.013
cytokine production GO:0001816 319 0.013
positive regulation of dna templated transcription elongation GO:0032786 2 0.013
histone ubiquitination GO:0016574 10 0.012
rho protein signal transduction GO:0007266 32 0.012
histone methylation GO:0016571 71 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
regulation of cell migration GO:0030334 219 0.012
fertilization GO:0009566 127 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
cellular homeostasis GO:0019725 240 0.012
regulation of cell activation GO:0050865 289 0.012
sensory perception GO:0007600 245 0.012
muscle cell differentiation GO:0042692 261 0.012
chromosome segregation GO:0007059 48 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
regulation of cell division GO:0051302 76 0.011
response to acid chemical GO:0001101 111 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.011
response to growth factor GO:0070848 198 0.011
mapk cascade GO:0000165 281 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
neuron apoptotic process GO:0051402 142 0.011
rna processing GO:0006396 105 0.011
rna interference GO:0016246 2 0.011
mrna splicing via spliceosome GO:0000398 43 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
actin cytoskeleton organization GO:0030036 220 0.011
regionalization GO:0003002 337 0.011
immune effector process GO:0002252 321 0.011
neuron death GO:0070997 154 0.011
protein processing GO:0016485 163 0.011
protein alkylation GO:0008213 81 0.011
leukocyte differentiation GO:0002521 342 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.011
blood vessel morphogenesis GO:0048514 285 0.011
endomembrane system organization GO:0010256 147 0.011
Rat
protein methylation GO:0006479 81 0.011
cell substrate adhesion GO:0031589 130 0.010
ossification GO:0001503 216 0.010
regulation of cell cycle process GO:0010564 160 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
protein polymerization GO:0051258 57 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
regulation of secretion GO:0051046 274 0.010
regulation of protein transport GO:0051223 163 0.010
dephosphorylation GO:0016311 129 0.010
retrograde protein transport er to cytosol GO:0030970 1 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
regulation of mapk cascade GO:0043408 248 0.010
nitrogen compound transport GO:0071705 271 0.010
inflammatory response GO:0006954 244 0.010

Nsfl1c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.141
disease of anatomical entity DOID:7 0 0.141
central nervous system disease DOID:331 0 0.141
neurodegenerative disease DOID:1289 0 0.095
motor neuron disease DOID:231 0 0.095
amyotrophic lateral sclerosis DOID:332 0 0.095