Mus musculus

0 known processes

Nucks1

nuclear casein kinase and cyclin-dependent kinase substrate 1

(Aliases: C78391,2700010L10Rik,Nucks,8430423A01Rik,AI647518)

Nucks1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
heterochromatin organization GO:0070828 4 0.526
nuclear division GO:0000280 158 0.476
compound eye development GO:0048749 1 0.446
heterochromatin assembly GO:0031507 2 0.364
chromatin modification GO:0016568 187 0.242
regulation of cell cycle GO:0051726 281 0.176
meiotic cell cycle process GO:1903046 77 0.172
organelle fission GO:0048285 170 0.157
positive regulation of apoptotic process GO:0043065 217 0.143
histone modification GO:0016570 159 0.139
microtubule cytoskeleton organization GO:0000226 157 0.138
mitotic cell cycle process GO:1903047 159 0.136
negative regulation of cellular component organization GO:0051129 194 0.131
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.130
regulation of organelle organization GO:0033043 289 0.124
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.122
negative regulation of phagocytosis GO:0050765 4 0.115
regulation of apoptotic signaling pathway GO:2001233 197 0.112
histone h4 k20 trimethylation GO:0034773 2 0.106
chromatin organization GO:0006325 206 0.106
meiotic nuclear division GO:0007126 115 0.104
negative regulation of molecular function GO:0044092 258 0.102
microtubule based process GO:0007017 236 0.101
protein methylation GO:0006479 81 0.099
regulation of transcription by chromatin organization GO:0034401 0 0.091
regulation of chromatin modification GO:1903308 57 0.090
histone acetylation GO:0016573 41 0.086
cellular amino acid metabolic process GO:0006520 103 0.085
protein modification by small protein conjugation or removal GO:0070647 207 0.085
mitotic cell cycle GO:0000278 195 0.082
apoptotic signaling pathway GO:0097190 306 0.081
protein acylation GO:0043543 64 0.076
regulation of circadian rhythm GO:0042752 58 0.076
translation GO:0006412 93 0.076
positive regulation of glycogen catabolic process GO:0045819 2 0.074
palate development GO:0060021 76 0.073
intrinsic apoptotic signaling pathway GO:0097193 132 0.071
macromolecule methylation GO:0043414 120 0.068
chromatin silencing GO:0006342 15 0.067
circadian rhythm GO:0007623 114 0.065
chromosome organization involved in meiosis GO:0070192 39 0.061
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.059
sensory perception GO:0007600 245 0.059
intracellular mrna localization GO:0008298 4 0.058
organic acid biosynthetic process GO:0016053 86 0.057
dna hypermethylation GO:0044026 3 0.057
chromatin assembly or disassembly GO:0006333 16 0.054
negative regulation of cell cycle GO:0045786 123 0.054
cellular macromolecule catabolic process GO:0044265 206 0.053
extrinsic apoptotic signaling pathway GO:0097191 126 0.053
cytoplasmic transport GO:0016482 234 0.051
positive regulation of apoptotic signaling pathway GO:2001235 95 0.051
cellular amine metabolic process GO:0044106 44 0.051
spermatid differentiation GO:0048515 115 0.051
stem cell differentiation GO:0048863 268 0.050
peptidyl lysine modification GO:0018205 77 0.050
response to molecule of bacterial origin GO:0002237 143 0.050
methylation GO:0032259 134 0.050
regulation of mrna stability GO:0043488 23 0.048
positive regulation of programmed cell death GO:0043068 218 0.047
histone h3 k9 dimethylation GO:0036123 4 0.046
positive regulation of proteolysis GO:0045862 85 0.046
protein import into nucleus GO:0006606 95 0.045
stem cell development GO:0048864 219 0.045
cellular ketone metabolic process GO:0042180 84 0.044
ventricular system development GO:0021591 27 0.044
maternal placenta development GO:0001893 20 0.044
regulation of peptidase activity GO:0052547 96 0.044
lateral inhibition GO:0046331 1 0.044
positive regulation of cell death GO:0010942 224 0.044
amine metabolic process GO:0009308 45 0.043
regulation of cellular component biogenesis GO:0044087 181 0.043
histone lysine methylation GO:0034968 50 0.042
gene silencing GO:0016458 38 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
macromolecule catabolic process GO:0009057 281 0.041
regulation of cellular catabolic process GO:0031329 242 0.039
glial cell apoptotic process GO:0034349 3 0.038
rhythmic process GO:0048511 174 0.038
oxidation reduction process GO:0055114 342 0.037
ear development GO:0043583 200 0.037
regulation of rna splicing GO:0043484 37 0.037
cellular response to dna damage stimulus GO:0006974 207 0.037
negative regulation of gene expression epigenetic GO:0045814 15 0.037
regulation of histone methylation GO:0031060 30 0.036
regulation of protein transport GO:0051223 163 0.036
nucleus organization GO:0006997 45 0.036
inflammatory response GO:0006954 244 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
dna metabolic process GO:0006259 303 0.036
negative regulation of b cell activation GO:0050869 27 0.036
multi multicellular organism process GO:0044706 109 0.035
mrna stabilization GO:0048255 9 0.035
peptidyl amino acid modification GO:0018193 336 0.035
oocyte axis specification GO:0007309 2 0.034
skin development GO:0043588 220 0.034
regulation of translation GO:0006417 71 0.033
response to lipopolysaccharide GO:0032496 128 0.033
cellular polysaccharide catabolic process GO:0044247 5 0.033
mesenchyme development GO:0060485 152 0.033
regulation of response to wounding GO:1903034 189 0.033
positive regulation of endopeptidase activity GO:0010950 43 0.032
negative regulation of protein modification process GO:0031400 163 0.032
membrane depolarization GO:0051899 64 0.031
mrna localization resulting in posttranscriptional regulation of gene expression GO:0010609 2 0.031
positive regulation of organelle organization GO:0010638 128 0.031
respiratory system development GO:0060541 190 0.031
b cell activation GO:0042113 161 0.030
negative regulation of immune system process GO:0002683 209 0.030
negative regulation of cell activation GO:0050866 111 0.030
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.030
protein alkylation GO:0008213 81 0.030
regulation of chromosome organization GO:0033044 83 0.030
covalent chromatin modification GO:0016569 163 0.030
protein maturation GO:0051604 176 0.030
response to glucocorticoid GO:0051384 20 0.029
multicellular organism growth GO:0035264 161 0.029
regulation of membrane potential GO:0042391 192 0.029
regulation of proteolysis GO:0030162 164 0.029
male gamete generation GO:0048232 285 0.028
cellular response to oxidative stress GO:0034599 76 0.028
organelle assembly GO:0070925 177 0.028
nucleocytoplasmic transport GO:0006913 139 0.028
meiotic cell cycle GO:0051321 122 0.027
regulation of transferase activity GO:0051338 263 0.027
response to radiation GO:0009314 165 0.027
negative regulation of apoptotic cell clearance GO:2000426 1 0.027
rna interference GO:0016246 2 0.027
carboxylic acid biosynthetic process GO:0046394 86 0.026
regulation of cell activation GO:0050865 289 0.026
protein processing GO:0016485 163 0.026
maintenance of protein localization in organelle GO:0072595 2 0.026
regulation of b cell activation GO:0050864 81 0.025
regulation of rna stability GO:0043487 26 0.025
chromosome segregation GO:0007059 48 0.025
positive regulation of histone methylation GO:0031062 16 0.025
cellular response to organic cyclic compound GO:0071407 87 0.024
dna templated transcription termination GO:0006353 4 0.024
regulation of chromatin organization GO:1902275 57 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
positive regulation of mrna metabolic process GO:1903313 17 0.024
cellular response to lipid GO:0071396 145 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
epithelial tube morphogenesis GO:0060562 303 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
protein localization to nucleus GO:0034504 121 0.023
dna packaging GO:0006323 30 0.022
germ cell proliferation GO:0036093 7 0.022
rna splicing via transesterification reactions GO:0000375 43 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
mitotic nuclear division GO:0007067 48 0.021
protein modification by small protein removal GO:0070646 21 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
spermatogenesis GO:0007283 284 0.021
rna processing GO:0006396 105 0.021
nuclear import GO:0051170 95 0.021
positive regulation of histone h3 k9 methylation GO:0051574 4 0.021
sensory perception of mechanical stimulus GO:0050954 107 0.021
positive regulation of cellular component biogenesis GO:0044089 94 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.021
ras protein signal transduction GO:0007265 77 0.020
rna stabilization GO:0043489 9 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
rna dependent dna replication GO:0006278 3 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
small molecule biosynthetic process GO:0044283 132 0.020
metaphase plate congression GO:0051310 2 0.020
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.020
negative regulation of rna splicing GO:0033119 12 0.019
response to uv GO:0009411 44 0.019
dna repair GO:0006281 107 0.019
maternal process involved in female pregnancy GO:0060135 32 0.019
sensory perception of sound GO:0007605 97 0.019
regulation of kinase activity GO:0043549 249 0.018
negative regulation of b cell differentiation GO:0045578 4 0.018
response to organic cyclic compound GO:0014070 198 0.018
mesenchymal cell differentiation GO:0048762 107 0.018
glycogen catabolic process GO:0005980 5 0.018
monocarboxylic acid biosynthetic process GO:0072330 61 0.017
spermatid development GO:0007286 108 0.017
histone methylation GO:0016571 71 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
oogenesis GO:0048477 56 0.017
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.017
regulation of nuclear division GO:0051783 56 0.017
negative regulation of organelle organization GO:0010639 90 0.017
cell fate commitment GO:0045165 210 0.017
intracellular protein transport GO:0006886 204 0.017
response to steroid hormone GO:0048545 56 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
protein targeting GO:0006605 143 0.016
protein ubiquitination GO:0016567 171 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
regulation of cell cycle process GO:0010564 160 0.016
cell type specific apoptotic process GO:0097285 268 0.016
response to extracellular stimulus GO:0009991 127 0.016
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
regulation of meiotic cell cycle GO:0051445 34 0.016
negative regulation of lymphocyte activation GO:0051250 91 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.016
skeletal system development GO:0001501 356 0.015
response to light stimulus GO:0009416 135 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.015
oocyte construction GO:0007308 2 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
dephosphorylation GO:0016311 129 0.015
meiotic chromosome condensation GO:0010032 3 0.015
regulation of cell division GO:0051302 76 0.015
regulation of double strand break repair via nonhomologous end joining GO:2001032 2 0.015
protein import GO:0017038 101 0.015
development of primary sexual characteristics GO:0045137 143 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
lung development GO:0030324 164 0.014
protein dna complex subunit organization GO:0071824 28 0.014
epidermis development GO:0008544 187 0.014
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
meiotic chromosome segregation GO:0045132 19 0.014
cajal body organization GO:0030576 1 0.014
angiogenesis GO:0001525 201 0.014
stem cell maintenance GO:0019827 130 0.014
internal peptidyl lysine acetylation GO:0018393 42 0.014
rna transport GO:0050658 18 0.013
positive regulation of protein modification process GO:0031401 299 0.013
zymogen activation GO:0031638 41 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of necrotic cell death GO:0010939 13 0.013
cellular response to steroid hormone stimulus GO:0071383 33 0.013
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
fatty acid biosynthetic process GO:0006633 41 0.013
mesenchymal cell development GO:0014031 93 0.013
positive regulation of protein transport GO:0051222 93 0.013
regulation of hydrolase activity GO:0051336 246 0.013
response to oxidative stress GO:0006979 123 0.013
regulation of defense response GO:0031347 233 0.013
nitrogen compound transport GO:0071705 271 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
wnt signaling pathway GO:0016055 188 0.013
spindle assembly involved in female meiosis GO:0007056 3 0.013
positive regulation of binding GO:0051099 49 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
chromatin assembly GO:0031497 13 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.012
female meiotic division GO:0007143 21 0.012
polysaccharide catabolic process GO:0000272 5 0.012
positive regulation of mrna splicing via spliceosome GO:0048026 11 0.012
cellular protein complex assembly GO:0043623 116 0.012
spindle organization GO:0007051 28 0.012
fatty acid derivative metabolic process GO:1901568 33 0.012
lipid biosynthetic process GO:0008610 179 0.012
epithelial to mesenchymal transition GO:0001837 47 0.012
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.012
spindle assembly involved in meiosis GO:0090306 4 0.012
cellular response to alcohol GO:0097306 23 0.011
histone exchange GO:0043486 8 0.011
activation of cysteine type endopeptidase activity GO:0097202 27 0.011
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
regulation of mitosis GO:0007088 29 0.011
dna catabolic process endonucleolytic GO:0000737 15 0.011
regulation of mrna metabolic process GO:1903311 43 0.011
respiratory tube development GO:0030323 167 0.011
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
male gonad development GO:0008584 88 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
regulation of histone modification GO:0031056 56 0.011
maintenance of protein location in nucleus GO:0051457 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
fatty acid metabolic process GO:0006631 121 0.011
homeostasis of number of cells GO:0048872 210 0.011
germ cell development GO:0007281 185 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
regulation of protein localization GO:0032880 231 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
myosin filament organization GO:0031033 3 0.010
positive regulation of peptidase activity GO:0010952 49 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
positive regulation of growth GO:0045927 104 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
nucleoside metabolic process GO:0009116 246 0.010

Nucks1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.075
nervous system disease DOID:863 0 0.075
central nervous system disease DOID:331 0 0.029
neurodegenerative disease DOID:1289 0 0.019