Mus musculus

0 known processes

Nuf2

NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)

(Aliases: C85691,2410003C07Rik,Cdca1,NUF2R,AU044112)

Nuf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ubiquitin dependent protein catabolic process GO:0006511 129 0.442
organelle fission GO:0048285 170 0.336
regulation of microtubule cytoskeleton organization GO:0070507 37 0.250
nuclear division GO:0000280 158 0.233
regulation of microtubule based process GO:0032886 52 0.231
cellular protein catabolic process GO:0044257 155 0.224
meiotic nuclear division GO:0007126 115 0.222
synaptonemal complex organization GO:0070193 15 0.184
female meiotic division GO:0007143 21 0.182
chromosome organization involved in meiosis GO:0070192 39 0.177
cellular macromolecule catabolic process GO:0044265 206 0.175
microtubule based process GO:0007017 236 0.174
mitotic cell cycle process GO:1903047 159 0.171
meiotic cell cycle GO:0051321 122 0.160
male meiosis GO:0007140 37 0.156
regulation of spindle organization GO:0090224 2 0.148
regulation of cellular catabolic process GO:0031329 242 0.147
proteasomal protein catabolic process GO:0010498 98 0.140
regulation of cell cycle GO:0051726 281 0.139
mitotic cell cycle GO:0000278 195 0.138
regulation of cellular protein catabolic process GO:1903362 61 0.133
dna metabolic process GO:0006259 303 0.131
regulation of cell cycle process GO:0010564 160 0.130
response to radiation GO:0009314 165 0.130
microtubule cytoskeleton organization GO:0000226 157 0.123
meiosis ii GO:0007135 7 0.119
regulation of chromosome segregation GO:0051983 21 0.118
meiotic cell cycle process GO:1903046 77 0.115
asymmetric stem cell division GO:0098722 3 0.113
protein catabolic process GO:0030163 221 0.112
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.111
microtubule depolymerization GO:0007019 15 0.109
positive regulation of chromosome segregation GO:0051984 4 0.101
modification dependent protein catabolic process GO:0019941 133 0.098
regulation of organelle organization GO:0033043 289 0.096
cellular response to dna damage stimulus GO:0006974 207 0.095
regulation of cellular response to stress GO:0080135 159 0.094
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.092
cytokinetic process GO:0032506 2 0.090
regulation of cytoskeleton organization GO:0051493 122 0.090
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.086
positive regulation of cellular catabolic process GO:0031331 148 0.082
regulation of cellular amino acid metabolic process GO:0006521 5 0.080
spindle assembly involved in mitosis GO:0090307 4 0.079
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.079
regulation of proteasomal protein catabolic process GO:0061136 46 0.077
regulation of protein maturation GO:1903317 96 0.075
sister chromatid segregation GO:0000819 20 0.075
negative regulation of protein metabolic process GO:0051248 282 0.074
mitotic cytokinesis GO:0000281 4 0.073
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.070
macromolecule catabolic process GO:0009057 281 0.070
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.070
microtubule polymerization or depolymerization GO:0031109 26 0.067
regulation of microtubule depolymerization GO:0031114 13 0.067
attachment of spindle microtubules to kinetochore GO:0008608 4 0.067
covalent chromatin modification GO:0016569 163 0.065
negative regulation of cellular protein metabolic process GO:0032269 247 0.065
synapsis GO:0007129 34 0.065
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.065
dna endoreduplication GO:0042023 4 0.062
protein modification by small protein conjugation or removal GO:0070647 207 0.062
modification dependent macromolecule catabolic process GO:0043632 133 0.061
regulation of protein depolymerization GO:1901879 26 0.056
chromatin organization GO:0006325 206 0.055
asymmetric neuroblast division GO:0055059 1 0.055
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.054
chromosome segregation GO:0007059 48 0.054
negative regulation of cellular component organization GO:0051129 194 0.053
histone serine phosphorylation GO:0035404 5 0.052
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.052
positive regulation of protein phosphorylation GO:0001934 242 0.052
regulation of mitotic cell cycle GO:0007346 126 0.051
synaptonemal complex assembly GO:0007130 13 0.051
negative regulation of cell cycle phase transition GO:1901988 48 0.051
aromatic compound catabolic process GO:0019439 286 0.050
regulation of protein complex disassembly GO:0043244 28 0.050
germ cell development GO:0007281 185 0.050
peptidyl serine phosphorylation GO:0018105 74 0.049
negative regulation of phosphorus metabolic process GO:0010563 184 0.049
cellular amine metabolic process GO:0044106 44 0.046
chromosome separation GO:0051304 14 0.045
chromatin modification GO:0016568 187 0.045
negative regulation of organelle organization GO:0010639 90 0.045
mitotic spindle organization GO:0007052 10 0.043
positive regulation of protein modification process GO:0031401 299 0.043
cellular ketone metabolic process GO:0042180 84 0.042
mitotic nuclear division GO:0007067 48 0.042
cellular protein complex disassembly GO:0043624 36 0.042
microtubule based movement GO:0007018 84 0.042
regulation of chromosome organization GO:0033044 83 0.041
negative regulation of cellular catabolic process GO:0031330 47 0.041
regulation of protein kinase activity GO:0045859 232 0.041
regulation of cell division GO:0051302 76 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.040
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.040
peptidyl amino acid modification GO:0018193 336 0.039
regulation of mitotic sister chromatid segregation GO:0033047 12 0.039
negative regulation of proteolysis GO:0045861 74 0.038
mitotic sister chromatid segregation GO:0000070 14 0.038
response to inorganic substance GO:0010035 96 0.038
cell division GO:0051301 120 0.037
cellular amino acid metabolic process GO:0006520 103 0.037
amine metabolic process GO:0009308 45 0.037
regulation of cellular amine metabolic process GO:0033238 20 0.036
negative regulation of cellular protein catabolic process GO:1903363 22 0.036
positive regulation of protein kinase activity GO:0045860 144 0.035
regulation of mitotic spindle organization GO:0060236 2 0.035
meiotic chromosome segregation GO:0045132 19 0.035
protein maturation GO:0051604 176 0.035
negative regulation of protein depolymerization GO:1901880 21 0.035
astral microtubule organization GO:0030953 3 0.034
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.034
regulation of protein processing GO:0070613 96 0.034
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.034
protein modification by small protein conjugation GO:0032446 187 0.033
male gamete generation GO:0048232 285 0.033
regulation of mitotic cell cycle phase transition GO:1901990 73 0.031
negative regulation of phosphate metabolic process GO:0045936 184 0.031
negative regulation of cell cycle GO:0045786 123 0.031
negative regulation of protein maturation GO:1903318 79 0.031
cleavage furrow formation GO:0036089 2 0.031
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.031
maintenance of location GO:0051235 89 0.031
regulation of transferase activity GO:0051338 263 0.030
regulation of protein catabolic process GO:0042176 108 0.030
oxidation reduction process GO:0055114 342 0.030
positive regulation of cell cycle GO:0045787 92 0.030
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.030
regulation of centriole replication GO:0046599 1 0.029
protein depolymerization GO:0051261 34 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
regulation of proteolysis GO:0030162 164 0.027
negative regulation of protein complex disassembly GO:0043242 22 0.027
negative regulation of protein processing GO:0010955 79 0.027
peptidyl serine modification GO:0018209 83 0.026
ribonucleoside catabolic process GO:0042454 206 0.026
neural precursor cell proliferation GO:0061351 121 0.026
response to organic cyclic compound GO:0014070 198 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.025
dephosphorylation GO:0016311 129 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
response to organonitrogen compound GO:0010243 246 0.025
nucleotide metabolic process GO:0009117 332 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.024
muscle cell differentiation GO:0042692 261 0.024
protein complex disassembly GO:0043241 40 0.024
negative regulation of protein modification process GO:0031400 163 0.024
negative regulation of nuclear division GO:0051784 19 0.024
ras protein signal transduction GO:0007265 77 0.024
mesodermal cell migration GO:0008078 4 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
regulation of protein localization GO:0032880 231 0.023
microtubule anchoring GO:0034453 9 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
cell fate commitment GO:0045165 210 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
negative regulation of protein catabolic process GO:0042177 36 0.023
regulation of cell projection organization GO:0031344 206 0.023
protein processing GO:0016485 163 0.022
negative regulation of molecular function GO:0044092 258 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
spermatogenesis GO:0007283 284 0.022
histone modification GO:0016570 159 0.022
development of primary sexual characteristics GO:0045137 143 0.022
protein localization to organelle GO:0033365 185 0.022
protein heterotetramerization GO:0051290 4 0.022
rho protein signal transduction GO:0007266 32 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
centrosome separation GO:0051299 4 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
negative regulation of cell cycle process GO:0010948 69 0.022
response to light stimulus GO:0009416 135 0.021
female meiosis chromosome segregation GO:0016321 1 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
dna replication independent nucleosome assembly GO:0006336 1 0.021
apoptotic signaling pathway GO:0097190 306 0.021
response to ionizing radiation GO:0010212 42 0.021
oogenesis GO:0048477 56 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
regulation of mapk cascade GO:0043408 248 0.020
cellular response to lipid GO:0071396 145 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
histone threonine phosphorylation GO:0035405 1 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
cellular lipid metabolic process GO:0044255 323 0.020
positive regulation of cell cycle phase transition GO:1901989 17 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
purine containing compound metabolic process GO:0072521 311 0.020
positive regulation of cell division GO:0051781 31 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
meiotic cytokinesis GO:0033206 5 0.020
positive regulation of organelle organization GO:0010638 128 0.020
double strand break repair GO:0006302 48 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
histone phosphorylation GO:0016572 9 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
regulation of double strand break repair via homologous recombination GO:0010569 2 0.019
dna replication GO:0006260 52 0.019
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 2 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
muscle tissue development GO:0060537 308 0.019
organelle assembly GO:0070925 177 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
negative regulation of cytoskeleton organization GO:0051494 36 0.018
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 9 0.018
response to oxidative stress GO:0006979 123 0.018
positive regulation of intracellular transport GO:0032388 70 0.018
mapk cascade GO:0000165 281 0.018
cell cycle g1 s phase transition GO:0044843 57 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
regulation of cellular component biogenesis GO:0044087 181 0.017
purine containing compound catabolic process GO:0072523 213 0.017
heterocycle catabolic process GO:0046700 280 0.017
intracellular mrna localization GO:0008298 4 0.017
cell adhesion GO:0007155 329 0.017
blood vessel morphogenesis GO:0048514 285 0.017
cellular response to radiation GO:0071478 28 0.017
actin cytoskeleton organization GO:0030036 220 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
positive regulation of nuclear division GO:0051785 27 0.017
regulation of kinase activity GO:0043549 249 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
positive regulation of cell cycle process GO:0090068 61 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
membrane organization GO:0061024 245 0.017
histone monoubiquitination GO:0010390 3 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
regulation of sister chromatid segregation GO:0033045 13 0.017
hexose metabolic process GO:0019318 98 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
mitotic spindle checkpoint GO:0071174 9 0.016
regulation of exit from mitosis GO:0007096 1 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
positive regulation of kinase activity GO:0033674 155 0.016
cell type specific apoptotic process GO:0097285 268 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
regulation of intracellular transport GO:0032386 159 0.016
negative regulation of sister chromatid segregation GO:0033046 7 0.016
regulation of system process GO:0044057 200 0.016
carbohydrate homeostasis GO:0033500 128 0.016
positive regulation of nervous system development GO:0051962 221 0.016
regulation of nuclear division GO:0051783 56 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
regulation of mitosis GO:0007088 29 0.016
centromeric sister chromatid cohesion GO:0070601 3 0.016
negative regulation of microtubule depolymerization GO:0007026 13 0.015
positive regulation of cell development GO:0010720 237 0.015
positive regulation of chromosome organization GO:2001252 33 0.015
lateral inhibition GO:0046331 1 0.015
cell maturation GO:0048469 127 0.015
gonad development GO:0008406 141 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
regulation of secretion GO:0051046 274 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
regulation of neuron projection development GO:0010975 169 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
cell cycle g2 m phase transition GO:0044839 20 0.015
glucose homeostasis GO:0042593 128 0.014
cytokinesis GO:0000910 17 0.014
homeostasis of number of cells GO:0048872 210 0.014
striated muscle tissue development GO:0014706 293 0.014
peptidyl threonine phosphorylation GO:0018107 31 0.014
lipid biosynthetic process GO:0008610 179 0.014
rna processing GO:0006396 105 0.014
regulation of neuron differentiation GO:0045664 281 0.014
muscle cell development GO:0055001 133 0.014
protein ubiquitination GO:0016567 171 0.014
dna ligation GO:0006266 3 0.014
nucleoside metabolic process GO:0009116 246 0.014
striated muscle cell development GO:0055002 125 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
nucleoside catabolic process GO:0009164 206 0.014
regulation of canonical wnt signaling pathway GO:0060828 82 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
regulation of rho gtpase activity GO:0032319 58 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
axonogenesis GO:0007409 274 0.014
cellular homeostasis GO:0019725 240 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
female gamete generation GO:0007292 74 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
translesion synthesis GO:0019985 1 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
response to reactive oxygen species GO:0000302 56 0.013
regulation of cell activation GO:0050865 289 0.013
regulation of hydrolase activity GO:0051336 246 0.013
negative regulation of chromosome organization GO:2001251 30 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
mitotic spindle assembly checkpoint GO:0007094 7 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
neural tube development GO:0021915 160 0.013
myeloid cell homeostasis GO:0002262 114 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.012
carbohydrate metabolic process GO:0005975 230 0.012
developmental maturation GO:0021700 193 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
meiosis i GO:0007127 60 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
neural tube formation GO:0001841 108 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
regulation of cytokinesis GO:0032465 5 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
negative regulation of cell division GO:0051782 24 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
positive regulation of transferase activity GO:0051347 167 0.012
wnt signaling pathway GO:0016055 188 0.012
regulation of hormone levels GO:0010817 211 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
maintenance of protein location in cell GO:0032507 20 0.012
macromolecular complex disassembly GO:0032984 43 0.012
positive regulation of protein import into nucleus GO:0042307 26 0.012
regulation of response to wounding GO:1903034 189 0.011
regulation of secretion by cell GO:1903530 249 0.011
g1 s transition of mitotic cell cycle GO:0000082 57 0.011
organophosphate catabolic process GO:0046434 232 0.011
nucleotide catabolic process GO:0009166 217 0.011
nitrogen compound transport GO:0071705 271 0.011
rac protein signal transduction GO:0016601 13 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of protein transport GO:0051223 163 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
organelle localization GO:0051640 179 0.011
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.011
myeloid cell differentiation GO:0030099 233 0.011
protein autophosphorylation GO:0046777 61 0.011
endomembrane system organization GO:0010256 147 0.011
rhythmic process GO:0048511 174 0.011
spindle assembly involved in female meiosis GO:0007056 3 0.011
angiogenesis GO:0001525 201 0.011
positive regulation of cytoplasmic transport GO:1903651 40 0.011
anatomical structure homeostasis GO:0060249 145 0.011
neuron migration GO:0001764 122 0.011
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 1 0.011
peptide hormone secretion GO:0030072 109 0.011
ossification GO:0001503 216 0.011
peptide transport GO:0015833 133 0.011
response to acid chemical GO:0001101 111 0.011
regulation of cell motility GO:2000145 236 0.011
protein localization to chromosome centromeric region GO:0071459 1 0.011
response to nutrient levels GO:0031667 109 0.011
blastocyst development GO:0001824 80 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.010
cellularization GO:0007349 1 0.010
neuroblast division GO:0055057 10 0.010
response to inactivity GO:0014854 4 0.010
regulation of neural precursor cell proliferation GO:2000177 70 0.010
positive regulation of mitotic cell cycle GO:0045931 41 0.010
sister chromatid cohesion GO:0007062 12 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
cellular protein complex assembly GO:0043623 116 0.010
circulatory system process GO:0003013 197 0.010
regulation of peptide transport GO:0090087 91 0.010
mitotic centrosome separation GO:0007100 4 0.010
myosin filament assembly GO:0031034 2 0.010
regulation of chromatin silencing GO:0031935 2 0.010
positive regulation of gtp catabolic process GO:0033126 85 0.010
forebrain development GO:0030900 302 0.010
neuroblast proliferation GO:0007405 49 0.010

Nuf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.094
cancer DOID:162 0 0.053
organ system cancer DOID:0050686 0 0.034
thoracic cancer DOID:5093 0 0.034
breast cancer DOID:1612 0 0.034
hematopoietic system disease DOID:74 0 0.022
immune system disease DOID:2914 0 0.022
disease of anatomical entity DOID:7 0 0.022