Mus musculus

55 known processes

Oas1a

2'-5' oligoadenylate synthetase 1A

(Aliases: L3)

Oas1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 10 0.998
Human
interspecies interaction between organisms GO:0044419 83 0.707
negative regulation of multi organism process GO:0043901 68 0.701
viral process GO:0016032 41 0.633
viral genome replication GO:0019079 17 0.433
Human
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.415
negative regulation of viral process GO:0048525 23 0.399
immune effector process GO:0002252 321 0.288
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.279
viral life cycle GO:0019058 36 0.166
Human
rig i signaling pathway GO:0039529 4 0.162
positive regulation of interferon alpha production GO:0032727 4 0.135
regulation of multi organism process GO:0043900 111 0.126
rna catabolic process GO:0006401 29 0.121
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.100
Mouse
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.100
aromatic compound catabolic process GO:0019439 286 0.094
Mouse
macromolecule catabolic process GO:0009057 281 0.091
Mouse
defense response to other organism GO:0098542 197 0.091
Human
heterocycle catabolic process GO:0046700 280 0.087
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.086
Mouse
regulation of viral genome replication GO:0045069 13 0.080
Human
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.078
organophosphate biosynthetic process GO:0090407 122 0.072
movement in host environment GO:0052126 15 0.071
nucleoside phosphate metabolic process GO:0006753 338 0.069
response to organic cyclic compound GO:0014070 198 0.067
nucleobase containing small molecule metabolic process GO:0055086 352 0.066
activation of innate immune response GO:0002218 56 0.065
cd4 positive alpha beta t cell activation GO:0035710 45 0.062
negative regulation of protein metabolic process GO:0051248 282 0.062
leukocyte differentiation GO:0002521 342 0.061
alpha beta t cell differentiation GO:0046632 69 0.060
positive regulation of rig i signaling pathway GO:1900246 1 0.058
regulation of rig i signaling pathway GO:0039535 2 0.058
nucleoside phosphate biosynthetic process GO:1901293 79 0.055
nucleotide metabolic process GO:0009117 332 0.054
innate immune response GO:0045087 157 0.054
negative regulation of cell proliferation GO:0008285 296 0.054
regulation of cellular ketone metabolic process GO:0010565 66 0.054
chromatin organization GO:0006325 206 0.052
leukocyte mediated immunity GO:0002443 174 0.052
response to type i interferon GO:0034340 12 0.052
response to dsrna GO:0043331 30 0.050
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.049
purine ribonucleoside catabolic process GO:0046130 205 0.048
purine containing compound catabolic process GO:0072523 213 0.048
skin development GO:0043588 220 0.048
cellular response to dna damage stimulus GO:0006974 207 0.046
t cell differentiation GO:0030217 174 0.046
immune response regulating signaling pathway GO:0002764 125 0.045
ribonucleoside catabolic process GO:0042454 206 0.045
t cell activation GO:0042110 289 0.045
protein modification by small protein conjugation or removal GO:0070647 207 0.043
protein modification by small protein conjugation GO:0032446 187 0.043
cellular ketone metabolic process GO:0042180 84 0.042
pre mirna processing GO:0031054 3 0.042
glycosyl compound metabolic process GO:1901657 246 0.041
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.041
dna metabolic process GO:0006259 303 0.041
regulation of t helper 2 cell cytokine production GO:2000551 3 0.040
stem cell differentiation GO:0048863 268 0.039
purine containing compound metabolic process GO:0072521 311 0.039
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.038
regulation of organelle organization GO:0033043 289 0.038
regulation of cytokine production GO:0001817 266 0.038
regulation of innate immune response GO:0045088 91 0.038
negative regulation of immune system process GO:0002683 209 0.038
lymphocyte differentiation GO:0030098 242 0.037
skeletal system development GO:0001501 356 0.037
myeloid cell differentiation GO:0030099 233 0.037
cellular protein catabolic process GO:0044257 155 0.036
nucleoside triphosphate catabolic process GO:0009143 205 0.036
epidermis development GO:0008544 187 0.035
regulation of cell activation GO:0050865 289 0.035
cation transport GO:0006812 399 0.035
organonitrogen compound biosynthetic process GO:1901566 192 0.034
gene silencing by mirna GO:0035195 10 0.034
positive regulation of viral genome replication GO:0045070 2 0.034
cellular amino acid metabolic process GO:0006520 103 0.033
b cell activation GO:0042113 161 0.032
purine ribonucleotide catabolic process GO:0009154 208 0.031
positive regulation of immune effector process GO:0002699 107 0.031
purine containing compound biosynthetic process GO:0072522 70 0.030
regulation of cellular component biogenesis GO:0044087 181 0.030
cell activation involved in immune response GO:0002263 126 0.030
cellular amine metabolic process GO:0044106 44 0.030
protein acylation GO:0043543 64 0.029
nucleoside catabolic process GO:0009164 206 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
negative regulation of t cell activation GO:0050868 65 0.029
negative regulation of molecular function GO:0044092 258 0.029
cellular lipid metabolic process GO:0044255 323 0.029
positive regulation of interferon beta production GO:0032728 8 0.028
type i interferon signaling pathway GO:0060337 10 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
regulation of neuron differentiation GO:0045664 281 0.028
adaptive immune response GO:0002250 155 0.027
carbohydrate metabolic process GO:0005975 230 0.027
Human
viral gene expression GO:0019080 3 0.027
immunoglobulin mediated immune response GO:0016064 69 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
cellular response to interferon alpha GO:0035457 4 0.027
Human
negative regulation of regulatory t cell differentiation GO:0045590 2 0.027
protein methylation GO:0006479 81 0.027
limb development GO:0060173 166 0.026
stem cell development GO:0048864 219 0.026
regulation of interferon beta production GO:0032648 13 0.026
spleen development GO:0048536 39 0.026
innate immune response activating signal transduction GO:0002758 50 0.026
positive regulation of cellular component biogenesis GO:0044089 94 0.026
negative regulation of cytokine production GO:0001818 84 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
mapk cascade GO:0000165 281 0.025
methylation GO:0032259 134 0.025
nucleotide biosynthetic process GO:0009165 78 0.025
cell type specific apoptotic process GO:0097285 268 0.025
negative regulation of immune effector process GO:0002698 55 0.024
calcium ion transport GO:0006816 159 0.024
defense response to bacterium GO:0042742 119 0.024
modification dependent protein catabolic process GO:0019941 133 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
rna interference GO:0016246 2 0.023
transmembrane transport GO:0055085 412 0.023
regulation of homeostatic process GO:0032844 182 0.023
spermatogenesis GO:0007283 284 0.023
cellular response to organic cyclic compound GO:0071407 87 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.023
cytokine production GO:0001816 319 0.023
regulation of protein transport GO:0051223 163 0.023
regulation of schwann cell proliferation GO:0010624 2 0.023
toll like receptor 7 signaling pathway GO:0034154 4 0.022
regulation of membrane potential GO:0042391 192 0.022
pattern recognition receptor signaling pathway GO:0002221 47 0.022
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.022
negative regulation of interferon beta production GO:0032688 3 0.022
neuronal action potential GO:0019228 54 0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.022
multicellular organismal signaling GO:0035637 91 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
endocytosis GO:0006897 168 0.022
organophosphate catabolic process GO:0046434 232 0.022
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 2 0.022
t helper 2 cell cytokine production GO:0035745 4 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
regulation of intracellular transport GO:0032386 159 0.021
protein ubiquitination GO:0016567 171 0.021
leukocyte activation involved in immune response GO:0002366 126 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
immune response activating signal transduction GO:0002757 116 0.021
viral transcription GO:0019083 3 0.021
regulation of t cell differentiation GO:0045580 83 0.021
maintenance of location GO:0051235 89 0.021
regulation of mapk cascade GO:0043408 248 0.021
organelle assembly GO:0070925 177 0.021
negative regulation of defense response to virus by host GO:0050689 1 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
peptidyl amino acid modification GO:0018193 336 0.020
cellular homeostasis GO:0019725 240 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
protein alkylation GO:0008213 81 0.020
regulation of hydrolase activity GO:0051336 246 0.020
Human
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
microtubule based process GO:0007017 236 0.020
type i interferon production GO:0032606 29 0.020
defense response to virus GO:0051607 68 0.019
Human
lymphocyte proliferation GO:0046651 164 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.019
alpha beta t cell activation GO:0046631 91 0.019
negative regulation of cell development GO:0010721 169 0.019
negative regulation of t cell differentiation GO:0045581 23 0.019
gene silencing GO:0016458 38 0.019
regulation of leukocyte proliferation GO:0070663 121 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
histone modification GO:0016570 159 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
divalent metal ion transport GO:0070838 172 0.019
positive regulation of nervous system development GO:0051962 221 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
regulation of transferase activity GO:0051338 263 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.019
purine nucleotide biosynthetic process GO:0006164 65 0.018
negative regulation of cell activation GO:0050866 111 0.018
gonad development GO:0008406 141 0.018
cell adhesion GO:0007155 329 0.018
myeloid leukocyte differentiation GO:0002573 119 0.018
meiotic cell cycle process GO:1903046 77 0.018
forebrain development GO:0030900 302 0.018
leukocyte proliferation GO:0070661 172 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
regulation of protein localization GO:0032880 231 0.018
cellular response to lipid GO:0071396 145 0.018
limb morphogenesis GO:0035108 149 0.018
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.018
mitotic cell cycle GO:0000278 195 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
ion transmembrane transport GO:0034220 361 0.018
muscle tissue development GO:0060537 308 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
homeostasis of number of cells GO:0048872 210 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
hair cycle GO:0042633 90 0.017
negative regulation of lymphocyte activation GO:0051250 91 0.017
intracellular protein transport GO:0006886 204 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
cytokine metabolic process GO:0042107 71 0.016
positive regulation of response to cytokine stimulus GO:0060760 11 0.016
action potential GO:0001508 78 0.016
nucleoside metabolic process GO:0009116 246 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
cellular chemical homeostasis GO:0055082 215 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
membrane fusion GO:0061025 38 0.016
production of small rna involved in gene silencing by rna GO:0070918 6 0.016
regulation of t cell activation GO:0050863 170 0.016
toll like receptor signaling pathway GO:0002224 38 0.016
multicellular organism growth GO:0035264 161 0.016
regulation of defense response to virus by host GO:0050691 8 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
macromolecule methylation GO:0043414 120 0.016
glycoprotein metabolic process GO:0009100 116 0.016
peptidyl lysine methylation GO:0018022 29 0.016
gland development GO:0048732 330 0.015
sensory perception GO:0007600 245 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
cell division GO:0051301 120 0.015
schwann cell proliferation GO:0014010 2 0.015
positive regulation of cell activation GO:0050867 158 0.015
cellular protein complex assembly GO:0043623 116 0.015
olfactory bulb interneuron differentiation GO:0021889 12 0.015
alpha beta t cell activation involved in immune response GO:0002287 31 0.015
transmission of nerve impulse GO:0019226 76 0.015
cytoplasmic transport GO:0016482 234 0.015
chromatin modification GO:0016568 187 0.015
negative regulation of nervous system development GO:0051961 156 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
male gamete generation GO:0048232 285 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.015
regulation of cell motility GO:2000145 236 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
cellular response to type i interferon GO:0071357 10 0.015
development of primary sexual characteristics GO:0045137 143 0.015
inorganic ion transmembrane transport GO:0098660 234 0.014
regulation of toll like receptor signaling pathway GO:0034121 20 0.014
positive regulation of leukocyte differentiation GO:1902107 86 0.014
isg15 protein conjugation GO:0032020 4 0.014
muscle cell differentiation GO:0042692 261 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
regulation of anatomical structure size GO:0090066 178 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
regulation of cell migration GO:0030334 219 0.014
wound healing GO:0042060 157 0.014
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.014
protein glycosylation GO:0006486 55 0.014
myelination in peripheral nervous system GO:0022011 19 0.014
hair follicle morphogenesis GO:0031069 29 0.014
spinal cord development GO:0021510 81 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.013
developmental maturation GO:0021700 193 0.013
t helper 17 cell lineage commitment GO:0072540 4 0.013
glycosylation GO:0070085 62 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
regulation of proteolysis GO:0030162 164 0.013
myeloid cell homeostasis GO:0002262 114 0.013
mda 5 signaling pathway GO:0039530 1 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
regulation of kinase activity GO:0043549 249 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
germ cell development GO:0007281 185 0.013
stem cell maintenance GO:0019827 130 0.013
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 10 0.013
connective tissue development GO:0061448 179 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
response to peptide GO:1901652 136 0.013
molting cycle GO:0042303 90 0.013
positive regulation of cytokine production GO:0001819 174 0.013
nucleotide catabolic process GO:0009166 217 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
cation homeostasis GO:0055080 212 0.013
female gamete generation GO:0007292 74 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
covalent chromatin modification GO:0016569 163 0.013
response to organonitrogen compound GO:0010243 246 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
divalent inorganic cation transport GO:0072511 178 0.013
female sex differentiation GO:0046660 84 0.012
interferon beta production GO:0032608 16 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
t cell differentiation involved in immune response GO:0002292 30 0.012
regulation of defense response GO:0031347 233 0.012
cardiac muscle tissue development GO:0048738 130 0.012
pallium development GO:0021543 120 0.012
carbohydrate homeostasis GO:0033500 128 0.012
Human
protein maturation GO:0051604 176 0.012
dna repair GO:0006281 107 0.012
regulation of cytokine biosynthetic process GO:0042035 59 0.012
lung development GO:0030324 164 0.012
protein processing GO:0016485 163 0.012
locomotory behavior GO:0007626 195 0.012
mesenchymal cell development GO:0014031 93 0.012
regulation of cell cycle GO:0051726 281 0.012
response to peptide hormone GO:0043434 127 0.012
amine metabolic process GO:0009308 45 0.012
regulation of system process GO:0044057 200 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
negative regulation of kinase activity GO:0033673 81 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
positive regulation of cell development GO:0010720 237 0.012
atp metabolic process GO:0046034 75 0.012
t helper cell differentiation GO:0042093 28 0.012
regulation of production of molecular mediator of immune response GO:0002700 65 0.012
nucleocytoplasmic transport GO:0006913 139 0.011
macromolecule glycosylation GO:0043413 55 0.011
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.011
digestive system development GO:0055123 200 0.011
ear development GO:0043583 200 0.011
negative regulation of leukocyte differentiation GO:1902106 51 0.011
regulation of binding GO:0051098 111 0.011
regulation of protein kinase activity GO:0045859 232 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
negative regulation of rig i signaling pathway GO:0039536 2 0.011
appendage development GO:0048736 166 0.011
cellular ion homeostasis GO:0006873 165 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
mrna stabilization GO:0048255 9 0.011
mesenchyme development GO:0060485 152 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
protein import GO:0017038 101 0.011
interferon beta biosynthetic process GO:0045350 4 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
regulation of mrna stability GO:0043488 23 0.011
neural crest cell differentiation GO:0014033 54 0.011
posttranscriptional gene silencing by rna GO:0035194 10 0.011
lipoprotein metabolic process GO:0042157 43 0.011
protein catabolic process GO:0030163 221 0.011
regulation of viral transcription GO:0046782 3 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
negative regulation of transferase activity GO:0051348 85 0.011
pyrimidine containing compound catabolic process GO:0072529 3 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
negative regulation of organelle organization GO:0010639 90 0.010
hair follicle development GO:0001942 85 0.010
regulation of secretion GO:0051046 274 0.010
purine nucleoside monophosphate catabolic process GO:0009128 58 0.010
respiratory tube development GO:0030323 167 0.010
lipoprotein biosynthetic process GO:0042158 33 0.010
erythrocyte differentiation GO:0030218 88 0.010
regulation of cellular component size GO:0032535 121 0.010

Oas1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org