Mus musculus

59 known processes

Oca2

oculocutaneous albinism II

(Aliases: p,D7Nic1,D7Icr28RN,D7H15S12)

Oca2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigmentation GO:0043473 71 0.998
pigment granule localization GO:0051875 13 0.983
pigment biosynthetic process GO:0046148 26 0.969
melanocyte differentiation GO:0030318 25 0.961
melanosome organization GO:0032438 8 0.949
melanin biosynthetic process GO:0042438 10 0.935
secondary metabolite biosynthetic process GO:0044550 11 0.925
ketone body metabolic process GO:1902224 3 0.915
pigment cell differentiation GO:0050931 27 0.792
developmental pigmentation GO:0048066 40 0.788
secondary metabolic process GO:0019748 18 0.750
cellular pigmentation GO:0033059 20 0.719
establishment of melanosome localization GO:0032401 11 0.704
melanosome localization GO:0032400 12 0.610
phenol containing compound biosynthetic process GO:0046189 21 0.549
melanosome transport GO:0032402 11 0.460
short chain fatty acid metabolic process GO:0046459 6 0.435
pigment granule organization GO:0048753 9 0.399
tyrosine metabolic process GO:0006570 4 0.344
neuronal action potential GO:0019228 54 0.332
vesicle localization GO:0051648 86 0.251
organic hydroxy compound biosynthetic process GO:1901617 77 0.248
aromatic amino acid family metabolic process GO:0009072 9 0.228
organelle localization GO:0051640 179 0.206
pigment granule transport GO:0051904 12 0.205
pigment metabolic process GO:0042440 32 0.197
melanin metabolic process GO:0006582 12 0.196
alpha amino acid metabolic process GO:1901605 59 0.183
visual perception GO:0007601 52 0.179
regulation of response to wounding GO:1903034 189 0.171
organic hydroxy compound metabolic process GO:1901615 203 0.165
cellular amino acid metabolic process GO:0006520 103 0.157
cellular ion homeostasis GO:0006873 165 0.150
sensory perception of light stimulus GO:0050953 54 0.149
cellular amine metabolic process GO:0044106 44 0.142
amine metabolic process GO:0009308 45 0.140
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.137
transmission of nerve impulse GO:0019226 76 0.136
positive regulation of nervous system development GO:0051962 221 0.134
regulation of cellular ketone metabolic process GO:0010565 66 0.130
vesicle organization GO:0016050 60 0.129
cognition GO:0050890 149 0.129
cation homeostasis GO:0055080 212 0.129
cell proliferation in forebrain GO:0021846 30 0.125
establishment of vesicle localization GO:0051650 81 0.123
cell junction assembly GO:0034329 52 0.121
neuropeptide signaling pathway GO:0007218 19 0.120
phospholipid metabolic process GO:0006644 87 0.118
multicellular organismal homeostasis GO:0048871 164 0.114
cellular lipid metabolic process GO:0044255 323 0.111
oviduct development GO:0060066 3 0.106
hair cycle GO:0042633 90 0.095
protein targeting GO:0006605 143 0.095
regulation of membrane potential GO:0042391 192 0.092
g protein coupled receptor signaling pathway GO:0007186 243 0.087
retina development in camera type eye GO:0060041 119 0.082
cellular ketone metabolic process GO:0042180 84 0.082
epithelial cell development GO:0002064 159 0.081
anion transport GO:0006820 177 0.080
phenol containing compound metabolic process GO:0018958 60 0.078
myelination GO:0042552 74 0.076
cation transmembrane transport GO:0098655 266 0.075
regulation of secretion by cell GO:1903530 249 0.074
midgut development GO:0007494 4 0.072
cell chemotaxis GO:0060326 81 0.072
sensory perception GO:0007600 245 0.070
transmembrane transport GO:0055085 412 0.069
inorganic ion transmembrane transport GO:0098660 234 0.068
regulation of cellular amine metabolic process GO:0033238 20 0.068
ribonucleotide metabolic process GO:0009259 291 0.062
inorganic cation transmembrane transport GO:0098662 207 0.062
forebrain ventricular zone progenitor cell division GO:0021869 6 0.061
memory GO:0007613 58 0.057
regulation of neural precursor cell proliferation GO:2000177 70 0.056
regulation of ph GO:0006885 26 0.055
lipid biosynthetic process GO:0008610 179 0.054
membrane organization GO:0061024 245 0.054
positive regulation of lymphocyte activation GO:0051251 140 0.051
positive regulation of growth GO:0045927 104 0.051
multicellular organismal signaling GO:0035637 91 0.050
organonitrogen compound biosynthetic process GO:1901566 192 0.050
catecholamine metabolic process GO:0006584 30 0.049
nitrogen compound transport GO:0071705 271 0.049
nucleoside metabolic process GO:0009116 246 0.047
response to organonitrogen compound GO:0010243 246 0.046
establishment of pigment granule localization GO:0051905 12 0.045
forebrain generation of neurons GO:0021872 63 0.045
response to molecule of bacterial origin GO:0002237 143 0.045
canonical wnt signaling pathway GO:0060070 130 0.045
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.045
positive regulation of neural precursor cell proliferation GO:2000179 42 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
regulation of saliva secretion GO:0046877 2 0.044
establishment of organelle localization GO:0051656 122 0.044
ion transmembrane transport GO:0034220 361 0.044
protein secretion GO:0009306 111 0.043
peptidyl tyrosine modification GO:0018212 145 0.042
negative regulation of response to wounding GO:1903035 77 0.042
secretory granule organization GO:0033363 20 0.042
gabaergic neuron differentiation GO:0097154 11 0.041
stem cell proliferation GO:0072089 117 0.041
neuroepithelial cell differentiation GO:0060563 37 0.040
bone remodeling GO:0046849 53 0.040
spermatogenesis GO:0007283 284 0.039
maintenance of location GO:0051235 89 0.038
synaptic transmission GO:0007268 329 0.038
hormone secretion GO:0046879 128 0.037
peptide transport GO:0015833 133 0.037
regulation of hormone levels GO:0010817 211 0.037
anatomical structure homeostasis GO:0060249 145 0.037
camera type eye development GO:0043010 266 0.036
exocytosis GO:0006887 121 0.036
paramesonephric duct development GO:0061205 3 0.035
positive regulation of cell activation GO:0050867 158 0.035
camp biosynthetic process GO:0006171 31 0.035
tube formation GO:0035148 140 0.035
neural precursor cell proliferation GO:0061351 121 0.034
sensory perception of chemical stimulus GO:0007606 51 0.034
protein localization to organelle GO:0033365 185 0.034
positive regulation of urine volume GO:0035810 6 0.034
skin development GO:0043588 220 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
negative regulation of sterol transport GO:0032372 4 0.034
ensheathment of neurons GO:0007272 76 0.034
monocarboxylic acid metabolic process GO:0032787 191 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
sensory perception of pain GO:0019233 47 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
acute inflammatory response GO:0002526 41 0.033
regulation of renal sodium excretion GO:0035813 3 0.033
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.032
adult walking behavior GO:0007628 41 0.032
positive regulation of cell development GO:0010720 237 0.032
nucleotide metabolic process GO:0009117 332 0.032
establishment or maintenance of cell polarity GO:0007163 86 0.032
cardiac cell fate determination GO:0060913 2 0.031
cellular divalent inorganic cation homeostasis GO:0072503 127 0.031
potassium ion transport GO:0006813 52 0.031
fertilization GO:0009566 127 0.031
cellular protein complex assembly GO:0043623 116 0.030
cation transport GO:0006812 399 0.030
positive regulation of catecholamine secretion GO:0033605 2 0.030
inorganic anion transport GO:0015698 43 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
regulation of ion transmembrane transport GO:0034765 119 0.029
regulation of body fluid levels GO:0050878 162 0.029
regulation of bone resorption GO:0045124 24 0.029
regulation of transmembrane transport GO:0034762 128 0.029
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.029
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.029
b cell activation GO:0042113 161 0.029
hair follicle development GO:0001942 85 0.029
nuclear division GO:0000280 158 0.029
substrate independent telencephalic tangential migration GO:0021826 8 0.029
genetic imprinting GO:0071514 27 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
sensory organ morphogenesis GO:0090596 242 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
intermediate filament cytoskeleton organization GO:0045104 26 0.028
purine containing compound catabolic process GO:0072523 213 0.028
synapse organization GO:0050808 125 0.028
neuronal stem cell division GO:0036445 10 0.028
forebrain neuroblast division GO:0021873 9 0.028
activation of adenylate cyclase activity GO:0007190 4 0.027
intracellular protein transport GO:0006886 204 0.027
wound healing GO:0042060 157 0.027
cell recognition GO:0008037 83 0.027
purine nucleotide biosynthetic process GO:0006164 65 0.027
chemotaxis GO:0006935 247 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
positive regulation of transmembrane transport GO:0034764 29 0.026
male gamete generation GO:0048232 285 0.026
cerebral cortex gabaergic interneuron development GO:0021894 6 0.026
single organism nuclear import GO:1902593 95 0.026
regulation of intracellular transport GO:0032386 159 0.026
spermatid development GO:0007286 108 0.026
locomotory behavior GO:0007626 195 0.025
negative regulation of lymphocyte activation GO:0051250 91 0.025
negative regulation of inflammatory response GO:0050728 61 0.025
insulin secretion GO:0030073 89 0.025
somatostatin receptor signaling pathway GO:0038169 2 0.025
peptide secretion GO:0002790 114 0.025
leukocyte differentiation GO:0002521 342 0.025
nucleoside phosphate biosynthetic process GO:1901293 79 0.025
protein import into nucleus GO:0006606 95 0.025
cytoplasmic transport GO:0016482 234 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
negative regulation of nucleotide biosynthetic process GO:0030809 6 0.024
negative regulation of cytokine production GO:0001818 84 0.024
purine containing compound metabolic process GO:0072521 311 0.024
cellular potassium ion transport GO:0071804 43 0.024
kidney development GO:0001822 213 0.024
peptidyl amino acid modification GO:0018193 336 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
adult behavior GO:0030534 135 0.023
cell adhesion GO:0007155 329 0.023
cell cell recognition GO:0009988 44 0.023
amide transport GO:0042886 138 0.023
heart morphogenesis GO:0003007 178 0.023
regulation of neuroblast proliferation GO:1902692 27 0.023
lipid localization GO:0010876 126 0.022
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.022
gastrin induced gastric acid secretion GO:0001698 1 0.022
negative regulation of camp metabolic process GO:0030815 5 0.022
somatic stem cell division GO:0048103 19 0.021
axonogenesis GO:0007409 274 0.021
inflammatory response GO:0006954 244 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
divalent metal ion transport GO:0070838 172 0.021
cell proliferation in hindbrain GO:0021534 10 0.021
regulation of anatomical structure size GO:0090066 178 0.021
sodium ion transport GO:0006814 73 0.021
wnt signaling pathway GO:0016055 188 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
response to peptide GO:1901652 136 0.021
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 4 0.021
response to radiation GO:0009314 165 0.021
microtubule based process GO:0007017 236 0.020
calcium ion transport GO:0006816 159 0.020
protein kinase a signaling GO:0010737 7 0.020
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.020
carboxylic acid biosynthetic process GO:0046394 86 0.020
peptide hormone secretion GO:0030072 109 0.020
digestive system development GO:0055123 200 0.020
organic acid biosynthetic process GO:0016053 86 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
cerebellar granule cell precursor proliferation GO:0021930 10 0.020
regulation of neuronal synaptic plasticity GO:0048168 30 0.020
regulation of circadian sleep wake cycle GO:0042749 3 0.020
cell cell junction organization GO:0045216 72 0.020
water homeostasis GO:0030104 27 0.020
intermediate filament based process GO:0045103 27 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
thymus development GO:0048538 41 0.019
adult locomotory behavior GO:0008344 91 0.019
learning or memory GO:0007611 148 0.019
mitotic cell cycle process GO:1903047 159 0.018
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.018
regulation of exocytosis GO:0017157 61 0.018
endocrine process GO:0050886 39 0.018
neurotransmitter transport GO:0006836 76 0.018
cell fate commitment GO:0045165 210 0.018
regulation of ion transport GO:0043269 215 0.018
organelle fission GO:0048285 170 0.018
regulation of calcium ion transport GO:0051924 69 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
establishment of glial blood brain barrier GO:0060857 2 0.018
interferon gamma production GO:0032609 67 0.018
calcium ion homeostasis GO:0055074 127 0.018
action potential GO:0001508 78 0.018
response to light stimulus GO:0009416 135 0.018
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
somatostatin signaling pathway GO:0038170 2 0.017
detection of stimulus GO:0051606 84 0.017
second messenger mediated signaling GO:0019932 73 0.017
positive regulation of neuroblast proliferation GO:0002052 19 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
regulation of macrophage colony stimulating factor production GO:1901256 1 0.017
cell cell junction assembly GO:0007043 27 0.017
response to amino acid GO:0043200 37 0.017
calcium ion dependent exocytosis GO:0017156 35 0.017
monovalent inorganic cation homeostasis GO:0055067 33 0.017
odontogenesis GO:0042476 78 0.016
response to inorganic substance GO:0010035 96 0.016
carboxylic acid transport GO:0046942 100 0.016
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.016
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
negative regulation of neuron projection regeneration GO:0070571 3 0.016
negative regulation of homeostatic process GO:0032845 71 0.016
ventricular zone neuroblast division GO:0021847 3 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
regulation of secretion GO:0051046 274 0.016
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
monosaccharide transport GO:0015749 58 0.016
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.016
cell proliferation in external granule layer GO:0021924 10 0.015
calcium mediated signaling GO:0019722 46 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.015
interneuron migration from the subpallium to the cortex GO:0021830 7 0.015
positive regulation of protein kinase c signaling GO:0090037 1 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
photoreceptor cell development GO:0042461 40 0.015
single fertilization GO:0007338 82 0.015
urogenital system development GO:0001655 261 0.015
positive regulation of protein kinase b signaling GO:0051897 32 0.015
protein import GO:0017038 101 0.015
regulation of tissue remodeling GO:0034103 38 0.015
rhodopsin mediated signaling pathway GO:0016056 4 0.015
positive regulation of organelle organization GO:0010638 128 0.015
protein kinase b signaling GO:0043491 74 0.015
sequestering of metal ion GO:0051238 19 0.015
fat cell differentiation GO:0045444 160 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
cellularization GO:0007349 1 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.014
cyclic purine nucleotide metabolic process GO:0052652 43 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.014
cyclic nucleotide metabolic process GO:0009187 59 0.014
protein localization to nucleus GO:0034504 121 0.014
camp metabolic process GO:0046058 40 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
nuclear transport GO:0051169 139 0.014
extracellular matrix organization GO:0030198 147 0.014
positive regulation of cytoskeleton organization GO:0051495 49 0.014
cellular response to starvation GO:0009267 57 0.014
eye pigmentation GO:0048069 3 0.014
cellular homeostasis GO:0019725 240 0.014
skeletal system development GO:0001501 356 0.014
cell division GO:0051301 120 0.014
transition metal ion transport GO:0000041 38 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
female sex differentiation GO:0046660 84 0.014
detection of light stimulus GO:0009583 25 0.014
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.014
leukocyte chemotaxis GO:0030595 69 0.013
keratinocyte differentiation GO:0030216 48 0.013
regulation of penile erection GO:0060405 1 0.013
regulation of camp biosynthetic process GO:0030817 25 0.013
trachea cartilage morphogenesis GO:0060535 4 0.013
positive regulation of camp mediated signaling GO:0043950 3 0.013
tissue homeostasis GO:0001894 115 0.013
gliogenesis GO:0042063 141 0.013
potassium ion homeostasis GO:0055075 4 0.013
immune effector process GO:0002252 321 0.013
regulation of organelle organization GO:0033043 289 0.013
regulation of blood pressure GO:0008217 93 0.013
olfactory learning GO:0008355 2 0.013
cardiac muscle tissue development GO:0048738 130 0.013
phototransduction visible light GO:0007603 6 0.013
regulation of cell cycle process GO:0010564 160 0.013
neuron maturation GO:0042551 29 0.013
fatty acid metabolic process GO:0006631 121 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
regulation of metal ion transport GO:0010959 106 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
carbohydrate homeostasis GO:0033500 128 0.012
male sex differentiation GO:0046661 109 0.012
response to drug GO:0042493 75 0.012
cell junction organization GO:0034330 77 0.012
regulation of blood circulation GO:1903522 93 0.012
response to extracellular stimulus GO:0009991 127 0.012
regulation of keratinocyte differentiation GO:0045616 11 0.012
oligopeptide transmembrane transport GO:0035672 4 0.012
pons maturation GO:0021586 3 0.012
phototransduction GO:0007602 17 0.012
positive regulation of ion transmembrane transport GO:0034767 24 0.012
neuroblast proliferation GO:0007405 49 0.012
chloride transport GO:0006821 32 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
acid secretion GO:0046717 33 0.012
binding of sperm to zona pellucida GO:0007339 34 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
positive regulation of kidney development GO:0090184 28 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
floor plate morphogenesis GO:0033505 3 0.012
regulation of hormone secretion GO:0046883 88 0.012
positive regulation of interferon gamma production GO:0032729 39 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
negative regulation of neuron differentiation GO:0045665 101 0.011
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.011
zymogen activation GO:0031638 41 0.011
negative regulation of cholesterol transport GO:0032375 4 0.011
positive regulation of protein kinase a signaling GO:0010739 2 0.011
rac protein signal transduction GO:0016601 13 0.011
regulation of t cell differentiation GO:0045580 83 0.011
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.011
positive regulation of exocytosis GO:0045921 20 0.011
lysosome organization GO:0007040 21 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
lymphocyte proliferation GO:0046651 164 0.011
meiotic nuclear division GO:0007126 115 0.011
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.011
regulation of cell projection organization GO:0031344 206 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
extracellular structure organization GO:0043062 148 0.011
negative regulation of nucleotide metabolic process GO:0045980 16 0.011
metanephric loop of henle development GO:0072236 4 0.011
axon ensheathment GO:0008366 76 0.011
regulation of homeostatic process GO:0032844 182 0.011
regulation of cell growth GO:0001558 91 0.011
response to nutrient levels GO:0031667 109 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.011
nuclear import GO:0051170 95 0.011
peripheral nervous system neuron axonogenesis GO:0048936 3 0.011
germ cell development GO:0007281 185 0.011
renal sodium excretion GO:0035812 3 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
heterocycle catabolic process GO:0046700 280 0.011
negative regulation of kinase activity GO:0033673 81 0.011
metanephric nephron development GO:0072210 34 0.011
regulation of inflammatory response GO:0050727 147 0.011
ribose phosphate metabolic process GO:0019693 291 0.010
regulation of cholesterol efflux GO:0010874 13 0.010
neuromuscular process controlling balance GO:0050885 59 0.010
histamine induced gastric acid secretion GO:0001697 1 0.010
regulation of developmental pigmentation GO:0048070 14 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
rhythmic process GO:0048511 174 0.010
optic nerve structural organization GO:0021633 2 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
defecation GO:0030421 1 0.010
adult feeding behavior GO:0008343 9 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
cardiocyte differentiation GO:0035051 87 0.010
cellular chemical homeostasis GO:0055082 215 0.010
stem cell division GO:0017145 30 0.010
maintenance of apical basal cell polarity GO:0035090 3 0.010
cellular response to abiotic stimulus GO:0071214 56 0.010

Oca2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 0 0.022
disease of anatomical entity DOID:7 0 0.017
mouth disease DOID:403 0 0.017
gastrointestinal system disease DOID:77 0 0.017
eye and adnexa disease DOID:1492 0 0.015
nervous system disease DOID:863 0 0.015
sensory system disease DOID:0050155 0 0.015
eye disease DOID:5614 0 0.015