Mus musculus

186 known processes

Onecut1

one cut domain, family member 1

(Aliases: OC-1,Hfh12,Hnf6b,HNF-6,Oc1,D9Ertd423e,Hnf6)

Onecut1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.987
Mouse
forebrain development GO:0030900 302 0.982
endocrine pancreas development GO:0031018 29 0.979
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.978
gland development GO:0048732 330 0.978
endocrine system development GO:0035270 98 0.973
cell fate commitment GO:0045165 210 0.967
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.966
pancreas development GO:0031016 57 0.963
auditory receptor cell fate determination GO:0042668 3 0.962
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.955
astrocyte fate commitment GO:0060018 4 0.951
hemangioblast cell differentiation GO:0060217 1 0.947
central nervous system neuron development GO:0021954 67 0.947
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.944
central nervous system neuron differentiation GO:0021953 162 0.943
dendrite development GO:0016358 115 0.942
Mouse
transdifferentiation GO:0060290 1 0.938
kidney development GO:0001822 213 0.938
Mouse
hexose metabolic process GO:0019318 98 0.929
regionalization GO:0003002 337 0.914
skin development GO:0043588 220 0.913
Mouse
cellular amino acid metabolic process GO:0006520 103 0.909
b cell differentiation GO:0030183 78 0.907
cellular amine metabolic process GO:0044106 44 0.903
cell fate determination GO:0001709 32 0.898
regulation of neuron differentiation GO:0045664 281 0.887
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.883
mitral valve morphogenesis GO:0003183 4 0.883
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.879
response to growth factor GO:0070848 198 0.878
epidermis development GO:0008544 187 0.877
Mouse
neuron fate specification GO:0048665 30 0.875
regulation of mast cell differentiation GO:0060375 3 0.875
learning or memory GO:0007611 148 0.869
Mouse
digestive system development GO:0055123 200 0.864
lymphocyte differentiation GO:0030098 242 0.863
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.862
liver development GO:0001889 66 0.861
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.861
forebrain neuron development GO:0021884 30 0.861
axonogenesis GO:0007409 274 0.854
epithelial cell development GO:0002064 159 0.854
organic hydroxy compound metabolic process GO:1901615 203 0.849
neural precursor cell proliferation GO:0061351 121 0.843
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.842
auditory receptor cell fate specification GO:0042667 1 0.840
hepaticobiliary system development GO:0061008 67 0.839
pancreatic a cell fate commitment GO:0003326 2 0.838
regulation of cellular ketone metabolic process GO:0010565 66 0.838
mechanoreceptor differentiation GO:0042490 67 0.836
Mouse
amine metabolic process GO:0009308 45 0.836
renal system development GO:0072001 225 0.830
Mouse
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.826
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.820
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.814
diencephalon development GO:0021536 63 0.804
regulation of kinase activity GO:0043549 249 0.798
cognition GO:0050890 149 0.791
Mouse
monosaccharide metabolic process GO:0005996 106 0.779
positive regulation of cell migration GO:0030335 109 0.779
embryonic epithelial tube formation GO:0001838 130 0.778
spinal cord development GO:0021510 81 0.777
regulation of cellular amine metabolic process GO:0033238 20 0.775
negative regulation of molecular function GO:0044092 258 0.766
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.760
neuron migration GO:0001764 122 0.757
pancreatic pp cell differentiation GO:0003312 2 0.756
blood vessel morphogenesis GO:0048514 285 0.756
regulation of cell motility GO:2000145 236 0.755
rhythmic process GO:0048511 174 0.745
ear development GO:0043583 200 0.743
Mouse
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.739
skeletal system morphogenesis GO:0048705 203 0.736
nephron tubule morphogenesis GO:0072078 68 0.736
forebrain morphogenesis GO:0048853 17 0.727
pancreatic pp cell fate commitment GO:0003329 2 0.727
regulation of cell migration GO:0030334 219 0.725
organelle assembly GO:0070925 177 0.720
negative regulation of cellular protein metabolic process GO:0032269 247 0.718
mesoderm morphogenesis GO:0048332 64 0.711
paraxial mesodermal cell differentiation GO:0048342 2 0.707
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.707
regulation of transferase activity GO:0051338 263 0.703
peripheral nervous system neuron differentiation GO:0048934 9 0.702
Mouse
axon guidance GO:0007411 141 0.701
regulation of cell projection organization GO:0031344 206 0.700
Mouse
dendritic spine development GO:0060996 30 0.697
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.696
glucose metabolic process GO:0006006 92 0.694
visceral serous pericardium development GO:0061032 2 0.692
neuron projection guidance GO:0097485 141 0.685
cell growth GO:0016049 130 0.684
neural tube development GO:0021915 160 0.683
b cell activation GO:0042113 161 0.681
regulation of retina development in camera type eye GO:1902866 3 0.679
mitral valve development GO:0003174 4 0.675
regulation of cellular amino acid metabolic process GO:0006521 5 0.670
negative regulation of cell proliferation GO:0008285 296 0.660
positive regulation of nervous system development GO:0051962 221 0.660
Mouse
ovulation cycle GO:0042698 59 0.653
ureteric bud morphogenesis GO:0060675 62 0.653
camera type eye development GO:0043010 266 0.653
regulation of organ morphogenesis GO:2000027 144 0.644
motor neuron migration GO:0097475 4 0.643
glandular epithelial cell differentiation GO:0002067 38 0.642
embryonic heart tube formation GO:0003144 1 0.640
urogenital system development GO:0001655 261 0.638
Mouse
hair cell differentiation GO:0035315 40 0.635
Mouse
ear morphogenesis GO:0042471 118 0.632
negative regulation of protein metabolic process GO:0051248 282 0.630
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.624
Mouse
inner ear morphogenesis GO:0042472 101 0.620
learning GO:0007612 98 0.616
positive regulation of exit from mitosis GO:0031536 1 0.614
regulation of neuron projection development GO:0010975 169 0.610
Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.608
positive regulation of synaptic plasticity GO:0031915 4 0.606
cell substrate adhesion GO:0031589 130 0.606
forebrain neuron differentiation GO:0021879 52 0.605
sensory organ morphogenesis GO:0090596 242 0.601
limb morphogenesis GO:0035108 149 0.599
hormone metabolic process GO:0042445 86 0.599
stem cell development GO:0048864 219 0.598
mitochondrion distribution GO:0048311 4 0.598
synapse organization GO:0050808 125 0.596
Mouse
glucose homeostasis GO:0042593 128 0.595
neuroblast proliferation GO:0007405 49 0.594
positive regulation of neuron projection development GO:0010976 79 0.593
Mouse
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.592
limb development GO:0060173 166 0.590
glial cell differentiation GO:0010001 131 0.589
mesoderm formation GO:0001707 62 0.575
cellular ketone metabolic process GO:0042180 84 0.572
epithelial tube morphogenesis GO:0060562 303 0.568
regulation of stem cell maintenance GO:2000036 17 0.562
regulation of body fluid levels GO:0050878 162 0.559
positive regulation of neuron differentiation GO:0045666 141 0.557
Mouse
kidney morphogenesis GO:0060993 83 0.557
cardiac right ventricle formation GO:0003219 3 0.554
regulation of system process GO:0044057 200 0.554
cell proliferation involved in heart valve development GO:2000793 2 0.549
mesonephros development GO:0001823 97 0.538
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.537
tendon cell differentiation GO:0035990 4 0.537
kidney epithelium development GO:0072073 121 0.535
anatomical structure homeostasis GO:0060249 145 0.534
regulation of bmp signaling pathway GO:0030510 60 0.533
germ cell development GO:0007281 185 0.532
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.530
mitotic cell cycle GO:0000278 195 0.529
carbohydrate homeostasis GO:0033500 128 0.525
placenta development GO:0001890 140 0.525
tendon formation GO:0035992 4 0.521
spermatogenesis GO:0007283 284 0.517
neuron projection extension GO:1990138 64 0.516
bmp signaling pathway GO:0030509 93 0.514
forebrain generation of neurons GO:0021872 63 0.513
erythrocyte maturation GO:0043249 6 0.511
embryonic heart tube development GO:0035050 65 0.500
stem cell differentiation GO:0048863 268 0.498
positive regulation of neural precursor cell proliferation GO:2000179 42 0.496
endoderm development GO:0007492 45 0.493
formation of primary germ layer GO:0001704 77 0.488
stem cell maintenance GO:0019827 130 0.487
mesenchymal cell development GO:0014031 93 0.487
peripheral nervous system neuron development GO:0048935 9 0.486
Mouse
gastrulation GO:0007369 116 0.484
positive regulation of keratinocyte proliferation GO:0010838 4 0.482
positive regulation of epithelial cell proliferation GO:0050679 68 0.480
regulation of response to wounding GO:1903034 189 0.480
extracellular matrix organization GO:0030198 147 0.479
regulation of stem cell differentiation GO:2000736 50 0.473
spinal cord motor neuron migration GO:0097476 4 0.472
asymmetric stem cell division GO:0098722 3 0.469
auditory receptor cell differentiation GO:0042491 37 0.468
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.466
cell differentiation in spinal cord GO:0021515 53 0.465
stem cell proliferation GO:0072089 117 0.464
regulation of dendritic spine morphogenesis GO:0061001 17 0.463
Mouse
associative learning GO:0008306 61 0.462
peptide secretion GO:0002790 114 0.460
astrocyte differentiation GO:0048708 43 0.459
respiratory tube development GO:0030323 167 0.459
Mouse
nephron tubule development GO:0072080 84 0.458
limbic system development GO:0021761 72 0.457
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.456
positive regulation of kinase activity GO:0033674 155 0.449
smoothened signaling pathway GO:0007224 105 0.449
dendritic spine morphogenesis GO:0060997 22 0.448
Mouse
dentate gyrus development GO:0021542 14 0.447
positive regulation of cellular amine metabolic process GO:0033240 5 0.442
regulation of protein kinase activity GO:0045859 232 0.442
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.442
cellular chemical homeostasis GO:0055082 215 0.440
cellular response to growth factor stimulus GO:0071363 197 0.439
apoptotic signaling pathway GO:0097190 306 0.439
epithelium migration GO:0090132 63 0.438
respiratory system development GO:0060541 190 0.436
Mouse
metanephric loop of henle development GO:0072236 4 0.436
positive regulation of semaphorin plexin signaling pathway GO:2001262 1 0.431
metanephric nephron development GO:0072210 34 0.430
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.429
regulation of cellular response to growth factor stimulus GO:0090287 82 0.427
aortic valve morphogenesis GO:0003180 4 0.427
mitotic cell cycle process GO:1903047 159 0.427
trophoblast giant cell differentiation GO:0060707 15 0.424
neural crest cell development GO:0014032 48 0.424
amacrine cell differentiation GO:0035881 5 0.424
positive regulation of cell development GO:0010720 237 0.423
Mouse
primary neural tube formation GO:0014020 95 0.421
establishment or maintenance of cell polarity GO:0007163 86 0.416
locomotory behavior GO:0007626 195 0.416
regulation of cell adhesion GO:0030155 154 0.413
female gamete generation GO:0007292 74 0.411
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.408
cell maturation GO:0048469 127 0.404
leukocyte differentiation GO:0002521 342 0.404
peripheral nervous system development GO:0007422 53 0.402
Mouse
transmembrane transport GO:0055085 412 0.401
ameboidal type cell migration GO:0001667 128 0.401
cellular response to hormone stimulus GO:0032870 150 0.398
regulation of cell growth GO:0001558 91 0.398
myeloid leukocyte differentiation GO:0002573 119 0.397
spleen development GO:0048536 39 0.397
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.393
circulatory system process GO:0003013 197 0.392
embryonic organ morphogenesis GO:0048562 276 0.392
intracellular distribution of mitochondria GO:0048312 1 0.391
striated muscle tissue development GO:0014706 293 0.390
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.390
cell adhesion GO:0007155 329 0.389
digestive tract morphogenesis GO:0048546 147 0.388
intestinal epithelial structure maintenance GO:0060729 4 0.386
response to oxygen levels GO:0070482 62 0.386
response to organonitrogen compound GO:0010243 246 0.382
lipid biosynthetic process GO:0008610 179 0.381
extracellular structure organization GO:0043062 148 0.379
skeletal muscle cell differentiation GO:0035914 66 0.378
phenol containing compound biosynthetic process GO:0046189 21 0.375
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.374
ureteric bud development GO:0001657 94 0.373
chemotaxis GO:0006935 247 0.372
cellular homeostasis GO:0019725 240 0.361
inner ear receptor cell differentiation GO:0060113 61 0.361
Mouse
positive regulation of stem cell differentiation GO:2000738 23 0.360
retina morphogenesis in camera type eye GO:0060042 45 0.356
positive regulation of cell cycle GO:0045787 92 0.356
peptidyl amino acid modification GO:0018193 336 0.353
nephron epithelium morphogenesis GO:0072088 68 0.352
regulation of glucose metabolic process GO:0010906 60 0.352
deltoid tuberosity development GO:0035993 3 0.349
positive regulation of protein kinase activity GO:0045860 144 0.347
catecholamine metabolic process GO:0006584 30 0.346
regulation of protein serine threonine kinase activity GO:0071900 157 0.346
peptide hormone secretion GO:0030072 109 0.345
metanephric nephron morphogenesis GO:0072273 19 0.345
regulation of exit from mitosis GO:0007096 1 0.343
bone development GO:0060348 120 0.343
epithelial to mesenchymal transition GO:0001837 47 0.343
morphogenesis of a branching epithelium GO:0061138 193 0.340
cilium assembly GO:0042384 81 0.339
cell fate specification involved in pattern specification GO:0060573 11 0.338
pallium development GO:0021543 120 0.338
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.337
regulation of secretion GO:0051046 274 0.336
embryonic limb morphogenesis GO:0030326 126 0.336
neural tube closure GO:0001843 90 0.336
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.335
response to decreased oxygen levels GO:0036293 59 0.331
positive regulation of protein phosphorylation GO:0001934 242 0.331
positive regulation of mitotic cell cycle GO:0045931 41 0.331
protein processing GO:0016485 163 0.329
regulation of transcription involved in cell fate commitment GO:0060850 15 0.325
multicellular organismal macromolecule metabolic process GO:0044259 19 0.324
epithelial cell morphogenesis GO:0003382 41 0.323
tube closure GO:0060606 91 0.319
epithelial cell proliferation GO:0050673 174 0.319
wound healing GO:0042060 157 0.314
monocarboxylic acid metabolic process GO:0032787 191 0.313
sclerotome development GO:0061056 4 0.311
negative regulation of cellular amine metabolic process GO:0033239 1 0.311
cerebral cortex development GO:0021987 86 0.311
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.310
olfactory bulb development GO:0021772 30 0.308
appendage morphogenesis GO:0035107 149 0.306
glial cell fate commitment GO:0021781 14 0.305
lung development GO:0030324 164 0.302
Mouse
positive regulation of growth GO:0045927 104 0.299
primitive streak formation GO:0090009 10 0.298
angiogenesis GO:0001525 201 0.297
tissue migration GO:0090130 68 0.297
morphogenesis of embryonic epithelium GO:0016331 159 0.294
mesodermal cell differentiation GO:0048333 22 0.293
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.293
telencephalon development GO:0021537 186 0.292
divalent inorganic cation transport GO:0072511 178 0.291
branching involved in ureteric bud morphogenesis GO:0001658 56 0.291
cell differentiation in hindbrain GO:0021533 24 0.288
negative regulation of dna binding GO:0043392 20 0.286
female sex differentiation GO:0046660 84 0.285
circadian rhythm GO:0007623 114 0.285
cellular glucose homeostasis GO:0001678 52 0.284
protein maturation GO:0051604 176 0.284
embryonic placenta development GO:0001892 98 0.283
regulation of protein processing GO:0070613 96 0.283
spinal cord association neuron differentiation GO:0021527 14 0.282
regulation of organ growth GO:0046620 61 0.282
carbohydrate metabolic process GO:0005975 230 0.281
cardiac cell fate determination GO:0060913 2 0.280
development of primary female sexual characteristics GO:0046545 73 0.279
hypophysis morphogenesis GO:0048850 3 0.277
cell fate specification GO:0001708 72 0.276
regulation of secretion by cell GO:1903530 249 0.275
regulation of anatomical structure size GO:0090066 178 0.273
regulation of organelle organization GO:0033043 289 0.273
small molecule biosynthetic process GO:0044283 132 0.272
positive regulation of bmp signaling pathway GO:0030513 23 0.272
mesenchyme morphogenesis GO:0072132 32 0.271
cellular response to glucose stimulus GO:0071333 45 0.270
ventral spinal cord interneuron fate commitment GO:0060579 14 0.269
central nervous system projection neuron axonogenesis GO:0021952 21 0.269
cellular response to calcium ion GO:0071277 14 0.268
regulation of cell division GO:0051302 76 0.268
nephron development GO:0072006 109 0.268
mesonephric tubule development GO:0072164 94 0.268
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.268
enteroendocrine cell differentiation GO:0035883 16 0.267
ectoderm formation GO:0001705 3 0.267
regulation of epithelial to mesenchymal transition GO:0010717 22 0.266
regulation of stem cell proliferation GO:0072091 78 0.266
skeletal system development GO:0001501 356 0.265
cerebellar cortex development GO:0021695 48 0.265
regulation of cell cycle process GO:0010564 160 0.264
regulation of apoptotic signaling pathway GO:2001233 197 0.263
morphogenesis of a polarized epithelium GO:0001738 37 0.262
positive regulation of apoptotic process GO:0043065 217 0.262
nephron epithelium development GO:0072009 92 0.261
neuron fate determination GO:0048664 9 0.261
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.260
cardiocyte differentiation GO:0035051 87 0.260
regulation of osteoblast differentiation GO:0045667 67 0.258
regulation of auditory receptor cell differentiation GO:0045607 4 0.256
regulation of cell cycle GO:0051726 281 0.256
organic hydroxy compound biosynthetic process GO:1901617 77 0.255
mesonephric tubule morphogenesis GO:0072171 63 0.254
regulation of homeostatic process GO:0032844 182 0.254
multicellular organism growth GO:0035264 161 0.253
neural tube formation GO:0001841 108 0.253
peptidyl tyrosine modification GO:0018212 145 0.252
nuclear division GO:0000280 158 0.248
regulation of heart contraction GO:0008016 77 0.247
regulation of cytokine production GO:0001817 266 0.245
regulation of myeloid cell differentiation GO:0045637 96 0.245
placenta blood vessel development GO:0060674 31 0.244
cell cycle arrest GO:0007050 37 0.243
regulation of steroid metabolic process GO:0019218 39 0.240
asymmetric neuroblast division GO:0055059 1 0.240
embryonic skeletal system morphogenesis GO:0048704 91 0.239
dopaminergic neuron differentiation GO:0071542 14 0.239
mapk cascade GO:0000165 281 0.238
mesenchymal to epithelial transition GO:0060231 12 0.238
positive regulation of cell projection organization GO:0031346 95 0.238
Mouse
determination of left right symmetry GO:0007368 80 0.237
connective tissue development GO:0061448 179 0.236
pancreatic a cell differentiation GO:0003310 7 0.236
cardiac epithelial to mesenchymal transition GO:0060317 18 0.234
sympathetic nervous system development GO:0048485 22 0.234
epithelial tube formation GO:0072175 130 0.234
lateral motor column neuron migration GO:0097477 3 0.233
skeletal muscle organ development GO:0060538 163 0.232
developmental maturation GO:0021700 193 0.232
response to peptide GO:1901652 136 0.231
endocardial cushion to mesenchymal transition GO:0090500 5 0.231
opsonization GO:0008228 3 0.230
synaptic transmission involved in micturition GO:0060084 3 0.229
memory GO:0007613 58 0.228
Mouse
regulation of hormone levels GO:0010817 211 0.226
neuronal stem cell division GO:0036445 10 0.226
collagen biosynthetic process GO:0032964 7 0.225
cellular response to carbohydrate stimulus GO:0071322 50 0.225
endocardial cushion morphogenesis GO:0003203 18 0.224
negative regulation of cell growth GO:0030308 44 0.223
cellular response to monosaccharide stimulus GO:0071326 47 0.222
apoptotic process involved in morphogenesis GO:0060561 25 0.222
collagen metabolic process GO:0032963 17 0.221
forelimb morphogenesis GO:0035136 40 0.221
axonal fasciculation GO:0007413 15 0.218
organic acid biosynthetic process GO:0016053 86 0.218
neuroblast division GO:0055057 10 0.217
regulation of cell substrate adhesion GO:0010810 73 0.217
negative regulation of synapse maturation GO:2000297 2 0.216
sensory system development GO:0048880 3 0.214
vascular process in circulatory system GO:0003018 62 0.213
epithelial cell fate commitment GO:0072148 13 0.213
sensory perception GO:0007600 245 0.213
multicellular organismal homeostasis GO:0048871 164 0.212
collagen fibril organization GO:0030199 32 0.209
maintenance of location GO:0051235 89 0.208
neuroendocrine cell differentiation GO:0061101 7 0.208
regulation of type b pancreatic cell apoptotic process GO:2000674 5 0.207
regulation of wound healing GO:0061041 40 0.206
morphogenesis of a branching structure GO:0001763 203 0.205
tube formation GO:0035148 140 0.204
nitrogen compound transport GO:0071705 271 0.204
organelle localization GO:0051640 179 0.204
heart morphogenesis GO:0003007 178 0.202
bone morphogenesis GO:0060349 78 0.201
regulation of carbohydrate metabolic process GO:0006109 75 0.201
cartilage development GO:0051216 140 0.200
negative regulation of nervous system development GO:0051961 156 0.199
carboxylic acid biosynthetic process GO:0046394 86 0.199
mammary gland duct morphogenesis GO:0060603 38 0.197
negative regulation of apoptotic signaling pathway GO:2001234 104 0.197
regulation of proteolysis GO:0030162 164 0.195
regulation of ion transport GO:0043269 215 0.195
androgen biosynthetic process GO:0006702 4 0.194
embryonic appendage morphogenesis GO:0035113 126 0.194
spinal cord patterning GO:0021511 25 0.193
regulation of digestive system process GO:0044058 13 0.193
regulation of neural precursor cell proliferation GO:2000177 70 0.193
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.192
regulation of map kinase activity GO:0043405 120 0.192
cardiac muscle tissue morphogenesis GO:0055008 44 0.191
central nervous system morphogenesis GO:0021551 2 0.191
neurohypophysis development GO:0021985 2 0.190
chromatin organization GO:0006325 206 0.190
regulation of epithelial cell proliferation GO:0050678 141 0.189
insulin secretion GO:0030073 89 0.189
regulation of peptide transport GO:0090087 91 0.189
myeloid cell differentiation GO:0030099 233 0.187
regulation of wnt signaling pathway GO:0030111 123 0.187
regulation of morphogenesis of a branching structure GO:0060688 53 0.187
endochondral bone morphogenesis GO:0060350 50 0.186
norepinephrine biosynthetic process GO:0042421 5 0.186
regulation of membrane potential GO:0042391 192 0.185
Mouse
chondrocyte differentiation GO:0002062 72 0.183
mitotic nuclear division GO:0007067 48 0.182
negative regulation of cell development GO:0010721 169 0.182
muscle cell differentiation GO:0042692 261 0.180
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.180
cell proliferation in forebrain GO:0021846 30 0.180
positive regulation of protein modification process GO:0031401 299 0.180
regulation of protein localization GO:0032880 231 0.179
cranial nerve development GO:0021545 41 0.179
central nervous system neuron axonogenesis GO:0021955 28 0.179
male gamete generation GO:0048232 285 0.178
neuron recognition GO:0008038 25 0.178
cellular carbohydrate metabolic process GO:0044262 119 0.178
myoblast differentiation GO:0045445 52 0.178
negative regulation of jak stat cascade GO:0046426 7 0.175
cerebellum formation GO:0021588 1 0.175
peripheral nervous system neuron axonogenesis GO:0048936 3 0.174
synapse assembly GO:0007416 56 0.172
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.172
digestion GO:0007586 40 0.172
phenol containing compound metabolic process GO:0018958 60 0.171
metanephric nephron tubule development GO:0072234 16 0.171
lipid localization GO:0010876 126 0.170
paraxial mesoderm development GO:0048339 18 0.169
regulation of angiogenesis GO:0045765 81 0.169
negative regulation of osteoblast differentiation GO:0045668 30 0.166
ossification GO:0001503 216 0.166
regulation of leukocyte differentiation GO:1902105 159 0.165
muscle tissue morphogenesis GO:0060415 53 0.165
hair follicle development GO:0001942 85 0.164
heart contraction GO:0060047 93 0.164
lens morphogenesis in camera type eye GO:0002089 24 0.164
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.164
gliogenesis GO:0042063 141 0.163
negative regulation of intracellular signal transduction GO:1902532 167 0.163
histone modification GO:0016570 159 0.162
detection of stimulus GO:0051606 84 0.162
digestive tract development GO:0048565 190 0.162
renal tubule development GO:0061326 87 0.161
mammary gland morphogenesis GO:0060443 54 0.161
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.161
regulation of canonical wnt signaling pathway GO:0060828 82 0.160
female gonad development GO:0008585 71 0.160
blood circulation GO:0008015 195 0.159
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.159
horizontal cell localization GO:0035852 1 0.158
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.158
cellular response to lipid GO:0071396 145 0.158
positive regulation of transferase activity GO:0051347 167 0.158
dorsal spinal cord development GO:0021516 20 0.158
t cell activation GO:0042110 289 0.157
mesenchymal cell differentiation GO:0048762 107 0.157
regulation of circadian rhythm GO:0042752 58 0.157
establishment of epithelial cell apical basal polarity GO:0045198 5 0.157
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.156
steroid metabolic process GO:0008202 119 0.155

Onecut1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
diabetes mellitus DOID:9351 0 0.451
type 2 diabetes mellitus DOID:9352 0 0.451
disease of metabolism DOID:0014667 0 0.451
carbohydrate metabolism disease DOID:0050013 0 0.451
glucose metabolism disease DOID:4194 0 0.451
acquired metabolic disease DOID:0060158 0 0.451