Mus musculus

56 known processes

Oprm1

opioid receptor, mu 1

(Aliases: Oprm,MOP-R,mor,MOR-1,MOR-1O,muOR)

Oprm1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neuropeptide signaling pathway GO:0007218 19 0.997
Human Mouse
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.961
Rat
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.940
blood circulation GO:0008015 195 0.854
g protein coupled receptor signaling pathway GO:0007186 243 0.837
amine metabolic process GO:0009308 45 0.791
response to pain GO:0048265 26 0.786
multicellular organismal response to stress GO:0033555 62 0.783
circulatory system process GO:0003013 197 0.766
g protein coupled receptor internalization GO:0002031 3 0.761
locomotory behavior GO:0007626 195 0.704
regulation of dopamine secretion GO:0014059 9 0.680
dopamine receptor signaling pathway GO:0007212 16 0.666
cerebral cortex neuron differentiation GO:0021895 19 0.665
regulation of ion transport GO:0043269 215 0.658
Rat
monoamine transport GO:0015844 33 0.634
regulation of cellular amine metabolic process GO:0033238 20 0.629
regulation of secretion by cell GO:1903530 249 0.596
Human Mouse
digestion GO:0007586 40 0.583
Mouse
forebrain development GO:0030900 302 0.583
negative regulation of cyclic nucleotide metabolic process GO:0030800 5 0.581
Rat
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.541
cyclic purine nucleotide metabolic process GO:0052652 43 0.537
Rat
negative regulation of synaptic transmission glutamatergic GO:0051967 4 0.530
regulation of blood pressure GO:0008217 93 0.521
catecholamine secretion GO:0050432 15 0.521
heart contraction GO:0060047 93 0.517
dopamine metabolic process GO:0042417 23 0.508
regulation of camp metabolic process GO:0030814 30 0.504
Rat
cellular ion homeostasis GO:0006873 165 0.470
Human
cellular amine metabolic process GO:0044106 44 0.469
sensory perception of pain GO:0019233 47 0.466
opioid receptor signaling pathway GO:0038003 5 0.455
positive regulation of cellular amine metabolic process GO:0033240 5 0.452
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.448
negative regulation of camp metabolic process GO:0030815 5 0.439
Rat
cyclic nucleotide metabolic process GO:0009187 59 0.434
Rat
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 5 0.424
Rat
gastric acid secretion GO:0001696 6 0.416
sensory perception GO:0007600 245 0.406
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.392
negative regulation of action potential GO:0045759 1 0.388
purine ribonucleotide metabolic process GO:0009150 290 0.385
Rat
regulation of cellular amino acid metabolic process GO:0006521 5 0.385
neuron migration GO:0001764 122 0.367
regulation of system process GO:0044057 200 0.365
Mouse Rat
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.347
regulation of dopamine metabolic process GO:0042053 10 0.337
regulation of hormone levels GO:0010817 211 0.331
Mouse
regulation of membrane potential GO:0042391 192 0.322
Rat
positive regulation of apoptotic process GO:0043065 217 0.320
dopamine uptake GO:0090494 4 0.319
gland development GO:0048732 330 0.318
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 12 0.311
somatostatin signaling pathway GO:0038170 2 0.308
Mouse
forebrain cell migration GO:0021885 58 0.304
response to corticosteroid GO:0031960 20 0.302
negative regulation of secretion GO:0051048 61 0.300
Human
digestive tract development GO:0048565 190 0.298
axonogenesis GO:0007409 274 0.298
response to organic cyclic compound GO:0014070 198 0.286
Rat
heart process GO:0003015 94 0.282
synaptic transmission GO:0007268 329 0.272
Human Mouse Rat
regulation of neurological system process GO:0031644 22 0.271
Rat
serotonin receptor signaling pathway GO:0007210 8 0.268
catecholamine transport GO:0051937 21 0.267
morphogenesis of a branching structure GO:0001763 203 0.264
purine nucleotide metabolic process GO:0006163 302 0.262
Rat
regulation of camp biosynthetic process GO:0030817 25 0.260
Rat
regulation of muscle system process GO:0090257 80 0.257
regulation of catecholamine secretion GO:0050433 12 0.253
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.246
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 2 0.246
regulation of catecholamine uptake involved in synaptic transmission GO:0051940 2 0.241
response to steroid hormone GO:0048545 56 0.239
cellular ketone metabolic process GO:0042180 84 0.226
regulation of action potential GO:0098900 4 0.225
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.224
dopamine uptake involved in synaptic transmission GO:0051583 4 0.218
negative regulation of cell proliferation GO:0008285 296 0.216
Mouse
central nervous system neuron differentiation GO:0021953 162 0.214
dopamine secretion GO:0014046 9 0.213
somatotropin secreting cell differentiation GO:0060126 4 0.210
ribose phosphate biosynthetic process GO:0046390 59 0.210
Rat
organonitrogen compound catabolic process GO:1901565 264 0.207
endocrine system development GO:0035270 98 0.203
positive regulation of catecholamine uptake involved in synaptic transmission GO:0051944 2 0.202
positive regulation of secretion GO:0051047 130 0.201
regulation of cellular ketone metabolic process GO:0010565 66 0.198
cation transport GO:0006812 399 0.195
Rat
acid secretion GO:0046717 33 0.192
negative regulation of purine nucleotide biosynthetic process GO:1900372 6 0.188
Rat
purine containing compound biosynthetic process GO:0072522 70 0.188
Rat
forebrain neuron differentiation GO:0021879 52 0.187
negative regulation of adenylate cyclase activity GO:0007194 1 0.186
Rat
cytokine production GO:0001816 319 0.182
immune effector process GO:0002252 321 0.181
regulation of peptide transport GO:0090087 91 0.178
Mouse
regulation of feeding behavior GO:0060259 3 0.178
membrane hyperpolarization GO:0060081 21 0.176
muscle system process GO:0003012 141 0.175
cell fate specification GO:0001708 72 0.170
embryonic organ morphogenesis GO:0048562 276 0.169
catecholamine uptake GO:0090493 4 0.168
cerebral cortex gabaergic interneuron development GO:0021894 6 0.168
response to extracellular stimulus GO:0009991 127 0.164
Rat
regulation of renal sodium excretion GO:0035813 3 0.162
morphogenesis of a branching epithelium GO:0061138 193 0.157
histamine induced gastric acid secretion GO:0001697 1 0.157
organic hydroxy compound transport GO:0015850 93 0.154
metal ion homeostasis GO:0055065 189 0.153
Human
mesenchymal cell differentiation GO:0048762 107 0.151
nucleotide metabolic process GO:0009117 332 0.151
Rat
negative regulation of lyase activity GO:0051350 1 0.150
Rat
digestive system development GO:0055123 200 0.150
peptide hormone secretion GO:0030072 109 0.148
Mouse
regulation of neuron differentiation GO:0045664 281 0.148
cation homeostasis GO:0055080 212 0.147
Human
nucleoside phosphate biosynthetic process GO:1901293 79 0.146
Rat
organonitrogen compound biosynthetic process GO:1901566 192 0.146
Rat
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.144
regulation of nucleotide biosynthetic process GO:0030808 34 0.141
Rat
multicellular organism growth GO:0035264 161 0.140
sodium ion transport GO:0006814 73 0.139
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.139
Rat
hormone secretion GO:0046879 128 0.138
Mouse
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.138
positive regulation of cell development GO:0010720 237 0.138
neural crest cell development GO:0014032 48 0.136
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.136
organic cyclic compound catabolic process GO:1901361 295 0.133
interneuron migration from the subpallium to the cortex GO:0021830 7 0.133
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.132
Rat
defense response to other organism GO:0098542 197 0.129
positive regulation of renal sodium excretion GO:0035815 2 0.128
second messenger mediated signaling GO:0019932 73 0.126
Human
amide transport GO:0042886 138 0.126
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.125
Rat
regulation of secretion GO:0051046 274 0.125
Human Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.125
monovalent inorganic cation homeostasis GO:0055067 33 0.124
negative regulation of molecular function GO:0044092 258 0.123
Rat
ribose phosphate metabolic process GO:0019693 291 0.123
Rat
striated muscle tissue development GO:0014706 293 0.122
cognition GO:0050890 149 0.121
nitrogen compound transport GO:0071705 271 0.121
Mouse
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.120
Rat
regulation of neuron projection development GO:0010975 169 0.119
feeding behavior GO:0007631 62 0.119
b cell activation GO:0042113 161 0.117
peptidyl amino acid modification GO:0018193 336 0.116
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.114
Human
muscle cell differentiation GO:0042692 261 0.114
negative regulation of nervous system development GO:0051961 156 0.114
regulation of saliva secretion GO:0046877 2 0.113
Mouse
purine nucleotide biosynthetic process GO:0006164 65 0.113
Rat
regulation of hormone secretion GO:0046883 88 0.112
Mouse
cardiac ventricle development GO:0003231 83 0.111
monosaccharide metabolic process GO:0005996 106 0.110
regulation of lyase activity GO:0051339 13 0.109
Rat
telencephalon cell migration GO:0022029 55 0.108
regulation of synaptic transmission gabaergic GO:0032228 17 0.106
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.106
Rat
regulation of systemic arterial blood pressure GO:0003073 61 0.105
organic hydroxy compound metabolic process GO:1901615 203 0.105
cyclic nucleotide biosynthetic process GO:0009190 44 0.105
Rat
regulation of blood circulation GO:1903522 93 0.103
cellular homeostasis GO:0019725 240 0.102
Human
inflammatory response GO:0006954 244 0.101
Rat
regulation of dopamine uptake involved in synaptic transmission GO:0051584 2 0.100
negative regulation of secretion by cell GO:1903531 54 0.100
Human
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.100
endocrine process GO:0050886 39 0.099
regulation of cell cycle GO:0051726 281 0.099
catecholamine metabolic process GO:0006584 30 0.098
midgut development GO:0007494 4 0.096
positive regulation of programmed cell death GO:0043068 218 0.095
regulation of hydrolase activity GO:0051336 246 0.095
divalent inorganic cation homeostasis GO:0072507 138 0.095
Human
cardiac muscle contraction GO:0060048 32 0.094
phenol containing compound metabolic process GO:0018958 60 0.094
mesenchyme development GO:0060485 152 0.094
cellular nitrogen compound catabolic process GO:0044270 280 0.092
calcium ion homeostasis GO:0055074 127 0.092
Human
cellular chemical homeostasis GO:0055082 215 0.091
Human
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.090
guanosine containing compound catabolic process GO:1901069 144 0.089
regulation of protein localization GO:0032880 231 0.089
Human
negative regulation of neuron differentiation GO:0045665 101 0.089
regulation of catecholamine metabolic process GO:0042069 10 0.089
regulation of camp mediated signaling GO:0043949 7 0.088
Human
negative regulation of nucleotide biosynthetic process GO:0030809 6 0.088
Rat
substrate independent telencephalic tangential migration GO:0021826 8 0.086
stem cell development GO:0048864 219 0.086
positive regulation of growth GO:0045927 104 0.085
ribonucleotide metabolic process GO:0009259 291 0.084
Rat
dopamine transport GO:0015872 15 0.084
glucose metabolic process GO:0006006 92 0.083
response to glucocorticoid GO:0051384 20 0.082
positive regulation of secretion by cell GO:1903532 114 0.082
purine ribonucleotide biosynthetic process GO:0009152 59 0.081
Rat
negative regulation of blood pressure GO:0045776 22 0.080
response to molecule of bacterial origin GO:0002237 143 0.080
Rat
diencephalon development GO:0021536 63 0.079
endocytosis GO:0006897 168 0.079
regulation of defense response GO:0031347 233 0.079
positive regulation of nucleotide catabolic process GO:0030813 88 0.079
camp metabolic process GO:0046058 40 0.079
Rat
cellular divalent inorganic cation homeostasis GO:0072503 127 0.078
Human
muscle hypertrophy GO:0014896 24 0.077
positive regulation of protein modification process GO:0031401 299 0.077
positive regulation of inflammatory response GO:0050729 47 0.076
forebrain neuron development GO:0021884 30 0.075
forebrain generation of neurons GO:0021872 63 0.074
blood vessel morphogenesis GO:0048514 285 0.074
negative regulation of camp biosynthetic process GO:0030818 5 0.074
Rat
circadian rhythm GO:0007623 114 0.074
positive regulation of nucleotide metabolic process GO:0045981 114 0.073
negative regulation of protein metabolic process GO:0051248 282 0.072
multi multicellular organism process GO:0044706 109 0.071
regulation of cell projection organization GO:0031344 206 0.071
male gamete generation GO:0048232 285 0.071
mapk cascade GO:0000165 281 0.070
Rat
gabaergic neuron differentiation GO:0097154 11 0.070
organic hydroxy compound biosynthetic process GO:1901617 77 0.070
regulation of mapk cascade GO:0043408 248 0.070
Rat
multi organism behavior GO:0051705 62 0.069
peptide secretion GO:0002790 114 0.069
Mouse
regulation of peptide hormone secretion GO:0090276 75 0.069
Mouse
heart trabecula morphogenesis GO:0061384 26 0.068
positive regulation of growth hormone secretion GO:0060124 3 0.068
epithelial tube morphogenesis GO:0060562 303 0.068
negative regulation of cell development GO:0010721 169 0.068
regulation of cellular catabolic process GO:0031329 242 0.068
cytosolic calcium ion homeostasis GO:0051480 70 0.067
Human
ameboidal type cell migration GO:0001667 128 0.067
response to growth factor GO:0070848 198 0.066
Rat
response to alcohol GO:0097305 48 0.066
Human Rat
positive regulation of nervous system development GO:0051962 221 0.065
organophosphate biosynthetic process GO:0090407 122 0.065
Rat
spermatogenesis GO:0007283 284 0.065
vasodilation GO:0042311 28 0.064
mesoderm development GO:0007498 100 0.063
nucleobase containing small molecule metabolic process GO:0055086 352 0.063
Rat
positive regulation of gtpase activity GO:0043547 85 0.063
purine containing compound metabolic process GO:0072521 311 0.062
Rat
regulation of cell activation GO:0050865 289 0.062
regulation of anatomical structure size GO:0090066 178 0.062
regulation of glial cell differentiation GO:0045685 41 0.062
cardiac chamber development GO:0003205 108 0.062
negative regulation of hydrolase activity GO:0051346 71 0.062
negative regulation of phosphate metabolic process GO:0045936 184 0.060
Rat
cellular calcium ion homeostasis GO:0006874 119 0.060
Human
peptide transport GO:0015833 133 0.059
Mouse
regulation of cell migration GO:0030334 219 0.059
Mouse
social behavior GO:0035176 21 0.059
guanosine containing compound metabolic process GO:1901068 144 0.058
heterocycle catabolic process GO:0046700 280 0.058
muscle tissue development GO:0060537 308 0.058
macromolecule catabolic process GO:0009057 281 0.057
response to organonitrogen compound GO:0010243 246 0.057
Rat
ribonucleotide biosynthetic process GO:0009260 59 0.056
Rat
central nervous system neuron development GO:0021954 67 0.056
response to nutrient levels GO:0031667 109 0.056
Rat
cell fate commitment GO:0045165 210 0.055
amine transport GO:0015837 21 0.055
regulation of protein processing GO:0070613 96 0.055
metanephric ascending thin limb development GO:0072218 2 0.055
leukocyte mediated immunity GO:0002443 174 0.055
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.055
heat generation GO:0031649 13 0.054
positive regulation of gtp catabolic process GO:0033126 85 0.054
oxidation reduction process GO:0055114 342 0.054
negative regulation of cell activation GO:0050866 111 0.053
cardiac muscle tissue morphogenesis GO:0055008 44 0.053
positive regulation of cell death GO:0010942 224 0.053
cellular response to organic cyclic compound GO:0071407 87 0.053
Rat
purine nucleoside triphosphate metabolic process GO:0009144 226 0.053
sensory system development GO:0048880 3 0.052
cellular response to hormone stimulus GO:0032870 150 0.052
Mouse
mesenchymal cell development GO:0014031 93 0.051
regulation of homeostatic process GO:0032844 182 0.051
regulation of heart rate GO:0002027 36 0.051
actin cytoskeleton organization GO:0030036 220 0.050
regulation of sodium ion transport GO:0002028 29 0.050
regulation of striated muscle contraction GO:0006942 25 0.050
inorganic ion transmembrane transport GO:0098660 234 0.050
Rat
striated muscle contraction GO:0006941 45 0.050
leukocyte differentiation GO:0002521 342 0.050
cellular amino acid metabolic process GO:0006520 103 0.050
negative regulation of protein secretion GO:0050709 20 0.049
Human
regulation of b cell activation GO:0050864 81 0.049
regulation of cardiac muscle contraction GO:0055117 21 0.049
monocarboxylic acid metabolic process GO:0032787 191 0.048
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 5 0.048
regulation of lipid metabolic process GO:0019216 118 0.048
regulation of protein transport GO:0051223 163 0.048
Human
gliogenesis GO:0042063 141 0.047
striated muscle hypertrophy GO:0014897 24 0.047
trophectodermal cell differentiation GO:0001829 21 0.047
olfactory bulb development GO:0021772 30 0.047
carbohydrate metabolic process GO:0005975 230 0.047
positive regulation of protein phosphorylation GO:0001934 242 0.047
heart growth GO:0060419 45 0.046
visual learning GO:0008542 44 0.046
positive regulation of hydrolase activity GO:0051345 148 0.046
metanephric loop of henle development GO:0072236 4 0.046
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.046
regulation of blood vessel size GO:0050880 56 0.045
regulation of synaptic transmission glutamatergic GO:0051966 19 0.045
metanephric thick ascending limb development GO:0072233 2 0.045
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.045
Rat
regulation of amine transport GO:0051952 21 0.045
pituitary gland development GO:0021983 38 0.045
regulation of protein complex assembly GO:0043254 83 0.045
leukocyte activation involved in immune response GO:0002366 126 0.044
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.044
regulation of multi organism process GO:0043900 111 0.044
growth involved in heart morphogenesis GO:0003241 4 0.044
norepinephrine transport GO:0015874 2 0.044
myeloid leukocyte mediated immunity GO:0002444 42 0.044
axon guidance GO:0007411 141 0.043
regulation of nucleotide metabolic process GO:0006140 169 0.043
Rat
positive regulation of nucleoside metabolic process GO:0045979 91 0.043
cell type specific apoptotic process GO:0097285 268 0.043
telencephalon development GO:0021537 186 0.043
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.043
synaptic transmission gabaergic GO:0051932 19 0.042
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.042
positive regulation of b cell activation GO:0050871 49 0.042
developmental growth involved in morphogenesis GO:0060560 138 0.042
regulation of nucleoside metabolic process GO:0009118 130 0.042
response to amine GO:0014075 16 0.042
corticotropin releasing hormone secretion GO:0043396 2 0.041
cardiac chamber morphogenesis GO:0003206 93 0.041
hormone metabolic process GO:0042445 86 0.041
gastrin induced gastric acid secretion GO:0001698 1 0.041
response to inorganic substance GO:0010035 96 0.041
cyclic nucleotide mediated signaling GO:0019935 18 0.041
Human
bone mineralization GO:0030282 54 0.040
stem cell differentiation GO:0048863 268 0.040
cell activation involved in immune response GO:0002263 126 0.040
cell division GO:0051301 120 0.040
regulation of purine nucleotide metabolic process GO:1900542 169 0.040
Rat
axial mesoderm formation GO:0048320 3 0.040
activation of adenylate cyclase activity GO:0007190 4 0.039
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.039
biomineral tissue development GO:0031214 64 0.039
protein secretion GO:0009306 111 0.039
Human
regulation of circadian rhythm GO:0042752 58 0.038
ribonucleoside metabolic process GO:0009119 245 0.038
regulation of epithelial cell proliferation GO:0050678 141 0.038
transmembrane transport GO:0055085 412 0.037
Rat
regulation of tube size GO:0035150 57 0.037
regulation of kinase activity GO:0043549 249 0.037
endocardial cushion formation GO:0003272 13 0.037
renal system process GO:0003014 48 0.037
protein processing GO:0016485 163 0.037
regulation of postsynaptic membrane potential GO:0060078 48 0.036
Rat
temperature homeostasis GO:0001659 26 0.036
response to radiation GO:0009314 165 0.036
response to oxygen levels GO:0070482 62 0.036
cellular metal ion homeostasis GO:0006875 151 0.036
Human
primary neural tube formation GO:0014020 95 0.036
peptidyl tyrosine phosphorylation GO:0018108 143 0.036
neural crest cell differentiation GO:0014033 54 0.036
regulation of ion homeostasis GO:2000021 64 0.036
skeletal muscle organ development GO:0060538 163 0.036
lymphocyte differentiation GO:0030098 242 0.036
regulation of cell division GO:0051302 76 0.035
glycosyl compound metabolic process GO:1901657 246 0.035
nucleotide catabolic process GO:0009166 217 0.035
paramesonephric duct development GO:0061205 3 0.035
regulation of organelle organization GO:0033043 289 0.035
regulation of peptide secretion GO:0002791 77 0.035
Mouse
pallium development GO:0021543 120 0.035
behavioral response to ethanol GO:0048149 8 0.035
Human
mesoderm morphogenesis GO:0048332 64 0.034
regulation of muscle contraction GO:0006937 49 0.034
blastocyst development GO:0001824 80 0.034
response to histamine GO:0034776 1 0.034
muscle tissue morphogenesis GO:0060415 53 0.034
regulation of cardiac muscle tissue growth GO:0055021 26 0.033
neural tube formation GO:0001841 108 0.033
neural tube development GO:0021915 160 0.033
branching involved in salivary gland morphogenesis GO:0060445 26 0.033
regulation of adenylate cyclase activity GO:0045761 10 0.033
Rat
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.033
insulin secretion GO:0030073 89 0.033
Mouse
action potential GO:0001508 78 0.032
rhodopsin mediated signaling pathway GO:0016056 4 0.032
negative regulation of growth GO:0045926 99 0.032
response to inactivity GO:0014854 4 0.032
b cell proliferation GO:0042100 53 0.032
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.032
regulation of purine nucleotide catabolic process GO:0033121 122 0.032
axial mesodermal cell fate commitment GO:0048322 1 0.032
hindbrain development GO:0030902 128 0.031
endocrine pancreas development GO:0031018 29 0.031
cardiac muscle tissue growth GO:0055017 37 0.031
cytokine secretion GO:0050663 72 0.031
chromatin organization GO:0006325 206 0.031
cell proliferation in external granule layer GO:0021924 10 0.031
small molecule biosynthetic process GO:0044283 132 0.030
adrenergic receptor signaling pathway GO:0071875 13 0.030
phenol containing compound biosynthetic process GO:0046189 21 0.030
peptidyl tyrosine modification GO:0018212 145 0.030
adenohypophysis development GO:0021984 14 0.030
conditioned taste aversion GO:0001661 4 0.030
carbohydrate homeostasis GO:0033500 128 0.030
Mouse
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.030
nuclear division GO:0000280 158 0.030
horizontal cell localization GO:0035852 1 0.030
negative regulation of ion transport GO:0043271 28 0.030
regulation of biomineral tissue development GO:0070167 33 0.030
angiogenesis GO:0001525 201 0.030
regulation of morphogenesis of a branching structure GO:0060688 53 0.030
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.029
neural crest cell migration GO:0001755 32 0.029
regulation of smoothened signaling pathway GO:0008589 58 0.029
cellular response to organonitrogen compound GO:0071417 145 0.029
Rat
lateral line system development GO:0048925 1 0.029
maternal process involved in female pregnancy GO:0060135 32 0.029
lymphocyte proliferation GO:0046651 164 0.029
receptor mediated endocytosis GO:0006898 51 0.028
negative regulation of nucleotide metabolic process GO:0045980 16 0.028
Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.028
developmental cell growth GO:0048588 84 0.028
muscle contraction GO:0006936 101 0.028
negative regulation of cell motility GO:2000146 61 0.028
Mouse
cellular lipid metabolic process GO:0044255 323 0.028
hexose transport GO:0008645 56 0.027
phospholipase c activating dopamine receptor signaling pathway GO:0060158 5 0.027
positive regulation of antimicrobial humoral response GO:0002760 2 0.027
regulation of asymmetric cell division GO:0009786 4 0.027
epithelial tube formation GO:0072175 130 0.027
adult locomotory behavior GO:0008344 91 0.027
Mouse
limbic system development GO:0021761 72 0.027
bmp signaling pathway GO:0030509 93 0.027
paraxial mesodermal cell fate commitment GO:0048343 2 0.027
regulation of interleukin 6 production GO:0032675 55 0.027
response to cocaine GO:0042220 14 0.027
Rat
response to nicotine GO:0035094 6 0.027
aromatic compound catabolic process GO:0019439 286 0.027
oviduct development GO:0060066 3 0.027
intracellular receptor signaling pathway GO:0030522 74 0.027
embryonic epithelial tube formation GO:0001838 130 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.026
renal sodium excretion GO:0035812 3 0.026
regulation of heart contraction GO:0008016 77 0.026
response to ethanol GO:0045471 18 0.026
Human Rat
regulation of cell cycle process GO:0010564 160 0.026
regulation of cyclase activity GO:0031279 13 0.026
Rat
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.026
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
proprioception GO:0019230 4 0.026
nucleoside metabolic process GO:0009116 246 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
regulation of cytokine production GO:0001817 266 0.025
myotube differentiation GO:0014902 105 0.025
receptor internalization GO:0031623 16 0.025
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.025
pancreas development GO:0031016 57 0.025
axial mesodermal cell fate specification GO:0048327 1 0.025
nucleoside catabolic process GO:0009164 206 0.025
regulation of wnt signaling pathway GO:0030111 123 0.024
nucleotide biosynthetic process GO:0009165 78 0.024
Rat
sensory perception of taste GO:0050909 18 0.024
monosaccharide transport GO:0015749 58 0.024
response to dietary excess GO:0002021 18 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
intracellular protein transport GO:0006886 204 0.024
organ growth GO:0035265 117 0.024
forelimb morphogenesis GO:0035136 40 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
sensory perception of mechanical stimulus GO:0050954 107 0.024
adult walking behavior GO:0007628 41 0.024
negative regulation of multi organism process GO:0043901 68 0.024
neuron projection guidance GO:0097485 141 0.024
neural tube closure GO:0001843 90 0.024
positive regulation of cardiac muscle contraction GO:0060452 2 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
intraspecies interaction between organisms GO:0051703 21 0.023
response to isoquinoline alkaloid GO:0014072 9 0.023
Rat
polarity specification of proximal distal axis GO:0010085 2 0.023
vascular process in circulatory system GO:0003018 62 0.023
epithelial cell proliferation GO:0050673 174 0.023
t cell proliferation GO:0042098 120 0.023
response to reactive oxygen species GO:0000302 56 0.023

Oprm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
organ system cancer DOID:0050686 0 0.038
bone development disease DOID:0080006 0 0.027
connective tissue disease DOID:65 0 0.027
disease of anatomical entity DOID:7 0 0.027
bone disease DOID:0080001 0 0.027
musculoskeletal system disease DOID:17 0 0.027