Mus musculus

22 known processes

Ostm1

osteopetrosis associated transmembrane protein 1

(Aliases: gl,HSPC019,1200002H13Rik)

Ostm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.326
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.280
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.265
metal ion homeostasis GO:0055065 189 0.264
regulation of reactive oxygen species metabolic process GO:2000377 40 0.254
copper ion homeostasis GO:0055070 9 0.195
cation homeostasis GO:0055080 212 0.182
reactive oxygen species biosynthetic process GO:1903409 8 0.181
transition metal ion homeostasis GO:0055076 54 0.173
iron ion homeostasis GO:0055072 36 0.166
cellular metal ion homeostasis GO:0006875 151 0.158
cellular copper ion homeostasis GO:0006878 8 0.157
response to ph GO:0009268 14 0.121
cellular homeostasis GO:0019725 240 0.114
reactive oxygen species metabolic process GO:0072593 84 0.112
endocytosis GO:0006897 168 0.091
ion transmembrane transport GO:0034220 361 0.089
cation transport GO:0006812 399 0.078
cellular transition metal ion homeostasis GO:0046916 32 0.078
transmembrane transport GO:0055085 412 0.071
membrane organization GO:0061024 245 0.071
cytoplasmic transport GO:0016482 234 0.053
apoptotic signaling pathway GO:0097190 306 0.052
membrane invagination GO:0010324 17 0.049
cellular lipid metabolic process GO:0044255 323 0.044
cellular amino acid metabolic process GO:0006520 103 0.043
cellular ketone metabolic process GO:0042180 84 0.042
inorganic ion transmembrane transport GO:0098660 234 0.039
cellular iron ion homeostasis GO:0006879 16 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
amine metabolic process GO:0009308 45 0.036
vesicle organization GO:0016050 60 0.035
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.034
cellular amine metabolic process GO:0044106 44 0.034
regulation of intracellular transport GO:0032386 159 0.034
immune effector process GO:0002252 321 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.032
cation transmembrane transport GO:0098655 266 0.031
carbohydrate metabolic process GO:0005975 230 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
phagocytosis GO:0006909 66 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
protein maturation GO:0051604 176 0.028
striated muscle tissue development GO:0014706 293 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
macromolecule catabolic process GO:0009057 281 0.027
regulation of secretion GO:0051046 274 0.027
cellular chemical homeostasis GO:0055082 215 0.027
nitrogen compound transport GO:0071705 271 0.026
retrograde transport endosome to golgi GO:0042147 2 0.026
nucleotide metabolic process GO:0009117 332 0.026
glycoprotein metabolic process GO:0009100 116 0.025
organelle localization GO:0051640 179 0.025
lysosome organization GO:0007040 21 0.024
leukocyte mediated immunity GO:0002443 174 0.024
sensory perception GO:0007600 245 0.024
exocytosis GO:0006887 121 0.024
regulation of lymphocyte activation GO:0051249 240 0.024
maintenance of location GO:0051235 89 0.024
ras protein signal transduction GO:0007265 77 0.023
rho protein signal transduction GO:0007266 32 0.023
divalent inorganic cation transport GO:0072511 178 0.023
cell type specific apoptotic process GO:0097285 268 0.023
regulation of defense response GO:0031347 233 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
protein processing GO:0016485 163 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
calcium ion homeostasis GO:0055074 127 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
oxidation reduction process GO:0055114 342 0.021
protein catabolic process GO:0030163 221 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.020
regulation of cytokine production GO:0001817 266 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
regulation of cell activation GO:0050865 289 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
sphingolipid metabolic process GO:0006665 45 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
muscle tissue development GO:0060537 308 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
regulation of organelle organization GO:0033043 289 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
amino acid transmembrane transport GO:0003333 37 0.018
regulation of protein localization GO:0032880 231 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
cell killing GO:0001906 67 0.018
cellular ion homeostasis GO:0006873 165 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
regulation of secretion by cell GO:1903530 249 0.017
gland development GO:0048732 330 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
peptide metabolic process GO:0006518 46 0.017
cellular amide metabolic process GO:0043603 58 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
nucleoside metabolic process GO:0009116 246 0.017
skeletal system development GO:0001501 356 0.016
intracellular protein transport GO:0006886 204 0.016
lipid biosynthetic process GO:0008610 179 0.016
purine containing compound metabolic process GO:0072521 311 0.016
regulation of exocytosis GO:0017157 61 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
organelle assembly GO:0070925 177 0.016
divalent metal ion transport GO:0070838 172 0.016
anion transmembrane transport GO:0098656 71 0.016
cellular protein catabolic process GO:0044257 155 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
regulation of hormone levels GO:0010817 211 0.016
calcium ion transport GO:0006816 159 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
blood circulation GO:0008015 195 0.016
amide transport GO:0042886 138 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.015
positive regulation of cell development GO:0010720 237 0.015
heterocycle catabolic process GO:0046700 280 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
positive regulation of cell death GO:0010942 224 0.015
urogenital system development GO:0001655 261 0.015
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
regulation of angiotensin levels in blood GO:0002002 4 0.015
membrane lipid metabolic process GO:0006643 53 0.015
regulation of cell projection organization GO:0031344 206 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.015
innate immune response GO:0045087 157 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
defense response to other organism GO:0098542 197 0.014
positive regulation of cell activation GO:0050867 158 0.014
kidney development GO:0001822 213 0.014
cell activation involved in immune response GO:0002263 126 0.014
compound eye development GO:0048749 1 0.014
cytokine production GO:0001816 319 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
protein ubiquitination GO:0016567 171 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
regulation of ion transport GO:0043269 215 0.014
skeletal muscle organ development GO:0060538 163 0.014
inflammatory response GO:0006954 244 0.014
regulation of hydrolase activity GO:0051336 246 0.014
negative regulation of molecular function GO:0044092 258 0.014
endomembrane system organization GO:0010256 147 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
myeloid cell differentiation GO:0030099 233 0.014
glycerolipid metabolic process GO:0046486 122 0.014
phospholipid metabolic process GO:0006644 87 0.014
circulatory system process GO:0003013 197 0.014
aromatic compound catabolic process GO:0019439 286 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
microtubule based process GO:0007017 236 0.014
sequestering of metal ion GO:0051238 19 0.014
regulation of cytoplasmic transport GO:1903649 112 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
rap protein signal transduction GO:0032486 3 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
nucleotide catabolic process GO:0009166 217 0.013
regulation of natural killer cell activation GO:0032814 22 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
organelle fission GO:0048285 170 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
natural killer cell activation involved in immune response GO:0002323 10 0.013
pigmentation GO:0043473 71 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
protein targeting GO:0006605 143 0.013
natural killer cell mediated cytotoxicity GO:0042267 29 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
organophosphate catabolic process GO:0046434 232 0.013
regulation of proteolysis GO:0030162 164 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
regulation of neuron differentiation GO:0045664 281 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
positive regulation of secretion GO:0051047 130 0.013
phagocytosis engulfment GO:0006911 16 0.013
response to organonitrogen compound GO:0010243 246 0.012
alcohol metabolic process GO:0006066 116 0.012
regulation of transmembrane transport GO:0034762 128 0.012
dephosphorylation GO:0016311 129 0.012
lipid localization GO:0010876 126 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
response to peptide hormone GO:0043434 127 0.012
alanine transport GO:0032328 4 0.012
peptidyl amino acid modification GO:0018193 336 0.012
regulation of cell cycle GO:0051726 281 0.012
sequestering of calcium ion GO:0051208 18 0.012
organic acid transport GO:0015849 101 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
regulation of mapk cascade GO:0043408 248 0.012
carbohydrate homeostasis GO:0033500 128 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
response to peptide GO:1901652 136 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
regulation of transferase activity GO:0051338 263 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
tissue remodeling GO:0048771 102 0.012
mapk cascade GO:0000165 281 0.012
amino acid transport GO:0006865 61 0.012
synapse organization GO:0050808 125 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
hormone secretion GO:0046879 128 0.011
small molecule biosynthetic process GO:0044283 132 0.011
sensory perception of sound GO:0007605 97 0.011
transmission of nerve impulse GO:0019226 76 0.011
germ cell development GO:0007281 185 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
lipid homeostasis GO:0055088 63 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of cell killing GO:0031341 40 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
ossification GO:0001503 216 0.011
regulation of angiotensin metabolic process GO:0060177 4 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
sphingolipid biosynthetic process GO:0030148 26 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
spermatid development GO:0007286 108 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of membrane potential GO:0042391 192 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
peptide transport GO:0015833 133 0.011
response to lipopolysaccharide GO:0032496 128 0.011
anatomical structure homeostasis GO:0060249 145 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of response to wounding GO:1903034 189 0.011
male gamete generation GO:0048232 285 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
regulation of blood pressure GO:0008217 93 0.011
t cell activation GO:0042110 289 0.011
macromolecule glycosylation GO:0043413 55 0.011
action potential GO:0001508 78 0.011
regulation of cellular response to stress GO:0080135 159 0.011
regulation of innate immune response GO:0045088 91 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
epidermis development GO:0008544 187 0.011
regulation of peptidase activity GO:0052547 96 0.011
glycosylation GO:0070085 62 0.010
lysosomal transport GO:0007041 10 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
dna metabolic process GO:0006259 303 0.010
b cell activation GO:0042113 161 0.010
peptide hormone secretion GO:0030072 109 0.010
glucose homeostasis GO:0042593 128 0.010
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
negative regulation of neuron death GO:1901215 98 0.010
cell adhesion GO:0007155 329 0.010
leukocyte differentiation GO:0002521 342 0.010
homeostasis of number of cells GO:0048872 210 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
response to oxygen levels GO:0070482 62 0.010
peptide secretion GO:0002790 114 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
response to organic cyclic compound GO:0014070 198 0.010
multicellular organismal signaling GO:0035637 91 0.010
neuron death GO:0070997 154 0.010
wound healing GO:0042060 157 0.010
regulation of microtubule based process GO:0032886 52 0.010
sensory organ morphogenesis GO:0090596 242 0.010
carboxylic acid transport GO:0046942 100 0.010
fat cell differentiation GO:0045444 160 0.010
tissue homeostasis GO:0001894 115 0.010
cellular response to lipid GO:0071396 145 0.010
natural killer cell mediated immunity GO:0002228 29 0.010
mitochondrion organization GO:0007005 134 0.010
renal system development GO:0072001 225 0.010
cell maturation GO:0048469 127 0.010
response to nutrient levels GO:0031667 109 0.010

Ostm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone remodeling disease DOID:0080005 0 0.642
Human
bone disease DOID:0080001 0 0.642
Human
osteopetrosis DOID:13533 0 0.642
Human
disease of anatomical entity DOID:7 0 0.642
Human
musculoskeletal system disease DOID:17 0 0.642
Human
connective tissue disease DOID:65 0 0.642
Human
osteosclerosis DOID:4254 0 0.642
Human
disease of metabolism DOID:0014667 0 0.067
nervous system disease DOID:863 0 0.031
lysosomal storage disease DOID:3211 0 0.016
inherited metabolic disorder DOID:655 0 0.016
central nervous system disease DOID:331 0 0.014
lipid storage disease DOID:9455 0 0.014
sphingolipidosis DOID:1927 0 0.013
brain disease DOID:936 0 0.013
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
immune system disease DOID:2914 0 0.010