|
|
activation of cdc42 gtpase activity
|
GO:0032864 |
2 |
1.000
|
|
|
|
neurofilament cytoskeleton organization
|
GO:0060052 |
10 |
1.000
|
|
|
|
mitotic centrosome separation
|
GO:0007100 |
4 |
1.000
|
Worm |
|
|
microtubule nucleation
|
GO:0007020 |
2 |
1.000
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.999
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.995
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
31 |
0.990
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.989
|
|
|
|
organelle transport along microtubule
|
GO:0072384 |
14 |
0.989
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
28 |
0.987
|
Human |
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.983
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
28 |
0.981
|
Human Worm Fly |
|
|
microtubule polymerization
|
GO:0046785 |
12 |
0.977
|
|
|
|
blastocyst growth
|
GO:0001832 |
23 |
0.974
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.962
|
|
|
|
inner cell mass cell proliferation
|
GO:0001833 |
15 |
0.958
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.949
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.948
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.944
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.943
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.941
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.938
|
|
|
|
retrograde axon cargo transport
|
GO:0008090 |
5 |
0.937
|
|
|
|
centrosome organization
|
GO:0051297 |
26 |
0.924
|
Worm Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.922
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.919
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.916
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.916
|
Rat |
|
|
intermediate filament based process
|
GO:0045103 |
27 |
0.914
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.904
|
|
|
|
centrosome duplication
|
GO:0051298 |
16 |
0.887
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.884
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.883
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.882
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.878
|
|
|
|
centrosome separation
|
GO:0051299 |
4 |
0.866
|
Worm Fly |
|
|
organelle localization
|
GO:0051640 |
179 |
0.859
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.858
|
Human |
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.847
|
Rat |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.843
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.841
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.837
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.829
|
Human Rat |
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.828
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.825
|
|
|
|
male meiosis
|
GO:0007140 |
37 |
0.825
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.821
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.815
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.802
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.800
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.800
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.799
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.797
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.795
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.784
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.756
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.756
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.749
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.748
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.745
|
Worm |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.736
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.733
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.732
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.731
|
Rat Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.728
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.721
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.717
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.717
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.713
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.712
|
|
|
|
centrosome cycle
|
GO:0007098 |
23 |
0.705
|
Worm Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.696
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.693
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.691
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.689
|
Worm |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.673
|
Worm |
|
|
blastocyst development
|
GO:0001824 |
80 |
0.673
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.672
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.669
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.656
|
|
|
|
activation of rho gtpase activity
|
GO:0032862 |
7 |
0.654
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.649
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.647
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.647
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.633
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.632
|
Rat Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.623
|
Human Rat Worm Fly |
|
|
nuclear division
|
GO:0000280 |
158 |
0.623
|
Worm |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.607
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.606
|
|
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
5 |
0.595
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.591
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.581
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.573
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.572
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
49 |
0.553
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.549
|
Human Worm |
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.549
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.548
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.532
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.529
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.525
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.509
|
|
|
|
activation of ras gtpase activity
|
GO:0032856 |
11 |
0.507
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.504
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.492
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.490
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.482
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.475
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.458
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.456
|
Human Worm |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.446
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.444
|
Worm |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.431
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.401
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.385
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.380
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.376
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.375
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.363
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.342
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.314
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.295
|
Rat |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.268
|
Rat Fly |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.265
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.248
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
12 |
0.245
|
Human Worm |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.244
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.239
|
Human Worm Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.235
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.231
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.228
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.224
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.213
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.210
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.209
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.201
|
|
|
|
centrosome localization
|
GO:0051642 |
13 |
0.197
|
Rat Fly |
|
|
establishment of spindle orientation
|
GO:0051294 |
15 |
0.188
|
Human Worm |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.177
|
Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.177
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.164
|
|
|
|
spindle organization
|
GO:0007051 |
28 |
0.157
|
Worm Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.156
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.149
|
Rat Fly |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.147
|
Human Rat Fly |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.139
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.138
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.137
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.133
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.128
|
|
|
|
metaphase plate congression
|
GO:0051310 |
2 |
0.120
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.114
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.107
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.103
|
Fly |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.101
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.098
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.097
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.095
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.093
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.087
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.085
|
Human Worm |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.082
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.082
|
Rat |
|
|
meiotic chromosome segregation
|
GO:0045132 |
19 |
0.082
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
10 |
0.082
|
Worm |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.081
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.080
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.079
|
Fly |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.076
|
Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.073
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.073
|
Rat |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.073
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.070
|
Rat |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.069
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.067
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.067
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.065
|
Worm |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.065
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.064
|
Rat |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.063
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.060
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.060
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.060
|
Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.060
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.058
|
Rat |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.057
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.056
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.056
|
Rat Fly |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.055
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.055
|
Fly |
|
|
nucleus localization
|
GO:0051647 |
20 |
0.054
|
Zebrafish Rat Worm Fly |
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.054
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.054
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.054
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.053
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.053
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.053
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.052
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
14 |
0.052
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.051
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.051
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.050
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.049
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.049
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.048
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.048
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.046
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.046
|
Fly |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.045
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.044
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.044
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.043
|
Fly |
|
|
male meiosis chromosome segregation
|
GO:0007060 |
3 |
0.043
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.042
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.042
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.041
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.041
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.041
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.040
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.040
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.040
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.039
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.039
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.038
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.038
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.038
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.037
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.037
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.036
|
|
|
|
positive regulation of nfat protein import into nucleus
|
GO:0051533 |
1 |
0.036
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.036
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.036
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.035
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.035
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.035
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.035
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.035
|
Rat Fly |
|
|
translation
|
GO:0006412 |
93 |
0.035
|
Fly |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.034
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.034
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.034
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.033
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.032
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.032
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.031
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.031
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.031
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.031
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.031
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.031
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.030
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.030
|
Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.030
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.030
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.030
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.030
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.030
|
Worm |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.030
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.029
|
|
|
|
sensory perception of touch
|
GO:0050975 |
2 |
0.029
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.029
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.029
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.029
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.028
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.028
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.028
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.027
|
Rat Fly |
|
|
response to radiation
|
GO:0009314 |
165 |
0.027
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.027
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.027
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.027
|
Zebrafish Fly |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.027
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.027
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.027
|
|
|
|
localization within membrane
|
GO:0051668 |
4 |
0.027
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.027
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.027
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.026
|
Worm |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.026
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.026
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.026
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.025
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.025
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.025
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.025
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.025
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.025
|
Rat |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.024
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.024
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.024
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.024
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.024
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.023
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.023
|
Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.023
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.023
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.023
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.023
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.023
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.023
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
7 |
0.022
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.022
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.022
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.022
|
Fly |
|
|
exocytosis
|
GO:0006887 |
121 |
0.022
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.022
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.021
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.021
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.021
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.021
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.021
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.021
|
Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.021
|
Rat |
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.021
|
|
|
|
establishment of meiotic spindle orientation
|
GO:0051296 |
1 |
0.021
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.020
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.020
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.020
|
Fly |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.020
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.020
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.020
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.020
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.020
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.019
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.019
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.019
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.019
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.019
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.019
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.019
|
Fly |
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.019
|
Worm |
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.019
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.019
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.019
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.019
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.019
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.018
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.018
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.018
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.018
|
|
|
|
positive regulation of macroautophagy
|
GO:0016239 |
3 |
0.018
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.018
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.018
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.018
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.018
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.018
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.018
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.018
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.018
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.018
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.018
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.017
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.017
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.017
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.017
|
|
|
|
golgi localization
|
GO:0051645 |
4 |
0.017
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.017
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.017
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.017
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.017
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.016
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.016
|
|
|
|
protein transport into membrane raft
|
GO:0032596 |
4 |
0.016
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.016
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.016
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.016
|
Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.016
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.016
|
Fly |
|
|
vacuole organization
|
GO:0007033 |
38 |
0.016
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.016
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.016
|
Worm |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.016
|
Rat |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.016
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.016
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.016
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.016
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.016
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.015
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.015
|
|
|
|
positive regulation of potassium ion transport
|
GO:0043268 |
3 |
0.015
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.015
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.015
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.015
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.015
|
|
|
|
cytokinetic process
|
GO:0032506 |
2 |
0.015
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.015
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.015
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.015
|
Worm |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.015
|
|
|
|
endoplasmic reticulum tubular network organization
|
GO:0071786 |
1 |
0.015
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.015
|
|
|
|
learning
|
GO:0007612 |
98 |
0.015
|
|
|
|
substantia nigra development
|
GO:0021762 |
2 |
0.015
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.014
|
|
|
|
positive regulation of microtubule polymerization or depolymerization
|
GO:0031112 |
3 |
0.014
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.014
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.014
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.014
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.014
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.014
|
Rat |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.014
|
Rat |
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.014
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.014
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.014
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.014
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.014
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.014
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.014
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.014
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.014
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.013
|
|
|
|
inter male aggressive behavior
|
GO:0002121 |
3 |
0.013
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.013
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.013
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.013
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.013
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.013
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.013
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.013
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.013
|
|
|
|
regulation of vacuole organization
|
GO:0044088 |
4 |
0.013
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.013
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.013
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.013
|
Worm |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.013
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.013
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.013
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.013
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.013
|
Rat |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.013
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.013
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.012
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.012
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.012
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.012
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.012
|
|
|
|
skeletal myofibril assembly
|
GO:0014866 |
4 |
0.012
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.012
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.012
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.012
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.012
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.012
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.012
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.012
|
Rat |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.012
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.012
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.012
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.012
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.012
|
|
|
|
regulation of synapse structural plasticity
|
GO:0051823 |
4 |
0.012
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.012
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.012
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.012
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.012
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.012
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.012
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.012
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.012
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.012
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.012
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.012
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.012
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.012
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.012
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.012
|
Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.012
|
Fly |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.012
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.011
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.011
|
|
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.011
|
Rat |
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.011
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.011
|
|
|
|
establishment of mitochondrion localization
|
GO:0051654 |
4 |
0.011
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.011
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.011
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.011
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.011
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.011
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.011
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.011
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.011
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.011
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.011
|
|
|
|
protein localization to chromosome centromeric region
|
GO:0071459 |
1 |
0.011
|
Fly |
|
|
cell killing
|
GO:0001906 |
67 |
0.011
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.011
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.011
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
34 |
0.011
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.011
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.011
|
|
