Mus musculus

0 known processes

Pak2

p21 protein (Cdc42/Rac)-activated kinase 2

(Aliases: KIAA4182,A130002K10Rik,5330420P17Rik,mKIAA4182,PAK-2,D16Ertd269e,AI836325)

Pak2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.363
epithelial tube morphogenesis GO:0060562 303 0.247
mapk cascade GO:0000165 281 0.199
Yeast
regulation of cellular amine metabolic process GO:0033238 20 0.180
ras protein signal transduction GO:0007265 77 0.165
modification dependent macromolecule catabolic process GO:0043632 133 0.152
cellular amino acid metabolic process GO:0006520 103 0.147
cytoplasmic transport GO:0016482 234 0.143
Yeast
regulation of mapk cascade GO:0043408 248 0.142
Yeast
ubiquitin dependent protein catabolic process GO:0006511 129 0.133
amine metabolic process GO:0009308 45 0.128
negative regulation of synaptic vesicle transport GO:1902804 3 0.125
cation homeostasis GO:0055080 212 0.119
carbohydrate derivative biosynthetic process GO:1901137 183 0.119
myeloid cell differentiation GO:0030099 233 0.113
cellular macromolecule catabolic process GO:0044265 206 0.111
rho protein signal transduction GO:0007266 32 0.109
peptidyl amino acid modification GO:0018193 336 0.106
Human Yeast
epithelial cell development GO:0002064 159 0.103
modification dependent protein catabolic process GO:0019941 133 0.100
nucleoside phosphate metabolic process GO:0006753 338 0.100
regulation of transferase activity GO:0051338 263 0.097
Human Yeast
organonitrogen compound biosynthetic process GO:1901566 192 0.095
organelle localization GO:0051640 179 0.093
developmental maturation GO:0021700 193 0.089
small gtpase mediated signal transduction GO:0007264 97 0.089
regulation of cellular amino acid metabolic process GO:0006521 5 0.089
regulation of cell activation GO:0050865 289 0.089
regulation of cell migration GO:0030334 219 0.088
regulation of cell motility GO:2000145 236 0.088
cellular protein catabolic process GO:0044257 155 0.087
purine ribonucleoside catabolic process GO:0046130 205 0.086
regulation of exocytosis GO:0017157 61 0.084
nucleotide metabolic process GO:0009117 332 0.084
activation of adenylate cyclase activity GO:0007190 4 0.083
cell type specific apoptotic process GO:0097285 268 0.083
epithelial tube formation GO:0072175 130 0.083
protein catabolic process GO:0030163 221 0.082
leukocyte differentiation GO:0002521 342 0.082
protein modification by small protein conjugation GO:0032446 187 0.081
purine nucleoside metabolic process GO:0042278 241 0.081
membrane organization GO:0061024 245 0.081
Mouse
regulation of membrane potential GO:0042391 192 0.080
morphogenesis of a branching structure GO:0001763 203 0.078
germ cell development GO:0007281 185 0.078
positive regulation of nucleotide metabolic process GO:0045981 114 0.077
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.074
regulation of neuron death GO:1901214 134 0.074
homeostasis of number of cells GO:0048872 210 0.074
exocytosis GO:0006887 121 0.073
regulation of protein kinase activity GO:0045859 232 0.073
Human Yeast
macromolecule catabolic process GO:0009057 281 0.072
regulation of protein localization GO:0032880 231 0.072
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.072
dna modification GO:0006304 50 0.071
cellular lipid metabolic process GO:0044255 323 0.071
tube formation GO:0035148 140 0.071
regulation of cell cycle process GO:0010564 160 0.070
Yeast
neural tube formation GO:0001841 108 0.070
activation of immune response GO:0002253 138 0.070
cellular amine metabolic process GO:0044106 44 0.069
negative regulation of protein modification process GO:0031400 163 0.068
dendrite development GO:0016358 115 0.065
Mouse
rap protein signal transduction GO:0032486 3 0.065
negative regulation of phosphate metabolic process GO:0045936 184 0.064
purine ribonucleotide metabolic process GO:0009150 290 0.063
positive regulation of protein phosphorylation GO:0001934 242 0.063
Human Yeast
carbon catabolite activation of transcription GO:0045991 4 0.062
negative regulation of neuron death GO:1901215 98 0.062
purine nucleotide metabolic process GO:0006163 302 0.062
positive regulation of cell development GO:0010720 237 0.062
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.061
protein ubiquitination GO:0016567 171 0.061
ribonucleoside triphosphate metabolic process GO:0009199 220 0.061
regulation of response to wounding GO:1903034 189 0.060
wound healing GO:0042060 157 0.059
stem cell proliferation GO:0072089 117 0.059
ribonucleotide metabolic process GO:0009259 291 0.059
regulation of kinase activity GO:0043549 249 0.059
Human Yeast
regulation of neuron projection development GO:0010975 169 0.059
mitotic cell cycle process GO:1903047 159 0.059
Yeast
negative regulation of phosphorylation GO:0042326 166 0.058
negative regulation of molecular function GO:0044092 258 0.058
Human
blood vessel morphogenesis GO:0048514 285 0.058
ribose phosphate biosynthetic process GO:0046390 59 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.058
genetic imprinting GO:0071514 27 0.057
nucleoside metabolic process GO:0009116 246 0.057
ribonucleotide biosynthetic process GO:0009260 59 0.057
cellular response to growth factor stimulus GO:0071363 197 0.056
regulation of vesicle mediated transport GO:0060627 139 0.056
establishment of endothelial blood brain barrier GO:0014045 3 0.056
negative regulation of cell proliferation GO:0008285 296 0.055
organophosphate biosynthetic process GO:0090407 122 0.054
response to growth factor GO:0070848 198 0.054
cellular response to peptide hormone stimulus GO:0071375 92 0.054
response to light stimulus GO:0009416 135 0.053
apical constriction GO:0003383 4 0.053
positive regulation of apoptotic process GO:0043065 217 0.053
Human Yeast
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.053
ribose phosphate metabolic process GO:0019693 291 0.053
regulation of lymphocyte activation GO:0051249 240 0.053
positive regulation of neuron differentiation GO:0045666 141 0.052
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.052
intrinsic apoptotic signaling pathway GO:0097193 132 0.052
immune effector process GO:0002252 321 0.051
maintenance of location GO:0051235 89 0.051
negative regulation of protein metabolic process GO:0051248 282 0.051
Human
regulation of purine nucleotide metabolic process GO:1900542 169 0.050
carbon catabolite regulation of transcription GO:0045990 4 0.050
cellular ion homeostasis GO:0006873 165 0.050
calcium ion homeostasis GO:0055074 127 0.049
transmembrane transport GO:0055085 412 0.049
Yeast
asymmetric neuroblast division GO:0055059 1 0.049
muscle cell differentiation GO:0042692 261 0.049
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.049
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.049
regulation of leukocyte differentiation GO:1902105 159 0.049
cellular homeostasis GO:0019725 240 0.049
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.048
neuron death GO:0070997 154 0.048
embryonic epithelial tube formation GO:0001838 130 0.048
organonitrogen compound catabolic process GO:1901565 264 0.048
positive regulation of hydrolase activity GO:0051345 148 0.048
t cell activation GO:0042110 289 0.048
morphogenesis of a branching epithelium GO:0061138 193 0.047
cell junction organization GO:0034330 77 0.047
Worm
divalent inorganic cation homeostasis GO:0072507 138 0.047
regulation of cellular component biogenesis GO:0044087 181 0.047
nuclear transport GO:0051169 139 0.047
Yeast
gonad development GO:0008406 141 0.046
Worm
gland development GO:0048732 330 0.046
leukocyte mediated immunity GO:0002443 174 0.046
negative regulation of intracellular signal transduction GO:1902532 167 0.045
digestive system development GO:0055123 200 0.045
negative regulation of phosphorus metabolic process GO:0010563 184 0.045
positive regulation of transcription by galactose GO:0000411 1 0.045
negative regulation of cellular amine metabolic process GO:0033239 1 0.045
metal ion homeostasis GO:0055065 189 0.044
positive regulation of cell death GO:0010942 224 0.044
Human Yeast
positive regulation of protein modification process GO:0031401 299 0.044
Human Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.044
cell cell junction organization GO:0045216 72 0.044
gtp metabolic process GO:0046039 144 0.044
regulation of t cell activation GO:0050863 170 0.043
glycosyl compound catabolic process GO:1901658 206 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.043
regulation of neuron apoptotic process GO:0043523 122 0.043
regulation of cell cycle GO:0051726 281 0.043
Yeast
cation transport GO:0006812 399 0.042
protein targeting GO:0006605 143 0.042
Yeast
photoreceptor cell differentiation GO:0046530 52 0.042
carbohydrate derivative catabolic process GO:1901136 231 0.042
localization within membrane GO:0051668 4 0.041
regulation of cell projection organization GO:0031344 206 0.041
protein modification by small protein conjugation or removal GO:0070647 207 0.041
regulation of organelle organization GO:0033043 289 0.041
Yeast
lymphocyte homeostasis GO:0002260 64 0.040
protein localization to nucleus GO:0034504 121 0.040
Yeast
immune response regulating signaling pathway GO:0002764 125 0.040
response to organonitrogen compound GO:0010243 246 0.040
guanosine containing compound catabolic process GO:1901069 144 0.040
regulation of interleukin 8 production GO:0032677 3 0.040
protein autophosphorylation GO:0046777 61 0.039
Human
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.039
photoreceptor cell morphogenesis GO:0008594 3 0.039
neural precursor cell proliferation GO:0061351 121 0.039
chromatin modification GO:0016568 187 0.039
Yeast
establishment of protein localization to organelle GO:0072594 118 0.039
Yeast
organic cyclic compound catabolic process GO:1901361 295 0.039
ribonucleotide catabolic process GO:0009261 208 0.039
purine nucleoside triphosphate catabolic process GO:0009146 203 0.038
regulation of nucleotide metabolic process GO:0006140 169 0.038
cell fate commitment GO:0045165 210 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
neuronal action potential GO:0019228 54 0.038
g protein coupled receptor signaling pathway GO:0007186 243 0.038
Yeast
neuron apoptotic process GO:0051402 142 0.037
sensory perception of umami taste GO:0050917 4 0.037
t cell differentiation in thymus GO:0033077 77 0.037
regulation of cytokine production GO:0001817 266 0.037
compound eye development GO:0048749 1 0.037
inorganic cation transmembrane transport GO:0098662 207 0.037
regulation of secretion by cell GO:1903530 249 0.037
immune response activating signal transduction GO:0002757 116 0.037
morphogenesis of embryonic epithelium GO:0016331 159 0.037
inflammatory response GO:0006954 244 0.036
establishment of organelle localization GO:0051656 122 0.036
purine nucleotide biosynthetic process GO:0006164 65 0.036
action potential GO:0001508 78 0.036
sequestering of calcium ion GO:0051208 18 0.036
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
positive regulation of nervous system development GO:0051962 221 0.035
positive regulation of programmed cell death GO:0043068 218 0.035
Human Yeast
camp biosynthetic process GO:0006171 31 0.035
cellular protein complex assembly GO:0043623 116 0.035
inorganic ion transmembrane transport GO:0098660 234 0.035
regulation of neuron differentiation GO:0045664 281 0.035
positive regulation of cytokine production GO:0001819 174 0.035
posttranscriptional regulation of gene expression GO:0010608 155 0.035
regulation of secretion GO:0051046 274 0.035
endocytosis GO:0006897 168 0.035
ribonucleoside metabolic process GO:0009119 245 0.034
i kappab kinase nf kappab signaling GO:0007249 85 0.034
positive regulation of cell projection organization GO:0031346 95 0.034
aromatic compound catabolic process GO:0019439 286 0.034
positive regulation of kinase activity GO:0033674 155 0.034
Human Yeast
stem cell development GO:0048864 219 0.033
mitotic cell cycle GO:0000278 195 0.033
Yeast
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.033
negative regulation of neuron apoptotic process GO:0043524 92 0.033
apoptotic signaling pathway GO:0097190 306 0.033
Human
actin filament based movement GO:0030048 23 0.033
myeloid leukocyte differentiation GO:0002573 119 0.033
oocyte construction GO:0007308 2 0.033
organelle fission GO:0048285 170 0.033
Yeast
carbohydrate metabolic process GO:0005975 230 0.033
negative regulation of homeostatic process GO:0032845 71 0.032
cellular response to hormone stimulus GO:0032870 150 0.032
regulation of insulin receptor signaling pathway GO:0046626 21 0.032
tube closure GO:0060606 91 0.032
endomembrane system organization GO:0010256 147 0.032
regulation of intracellular transport GO:0032386 159 0.032
Yeast
methylation GO:0032259 134 0.032
establishment or maintenance of cell polarity GO:0007163 86 0.032
Yeast
cation transmembrane transport GO:0098655 266 0.031
t cell apoptotic process GO:0070231 39 0.031
lipid biosynthetic process GO:0008610 179 0.031
t cell differentiation GO:0030217 174 0.031
response to radiation GO:0009314 165 0.031
neural tube development GO:0021915 160 0.031
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.031
nucleoside catabolic process GO:0009164 206 0.030
cell division GO:0051301 120 0.030
Yeast
oocyte axis specification GO:0007309 2 0.030
leukocyte activation involved in immune response GO:0002366 126 0.030
regulation of lyase activity GO:0051339 13 0.030
sequestering of metal ion GO:0051238 19 0.030
guanosine containing compound metabolic process GO:1901068 144 0.030
nucleotide biosynthetic process GO:0009165 78 0.030
nucleoside phosphate biosynthetic process GO:1901293 79 0.030
dephosphorylation GO:0016311 129 0.030
sensory organ morphogenesis GO:0090596 242 0.030
cellular response to peptide GO:1901653 92 0.029
photoreceptor cell development GO:0042461 40 0.029
cellular divalent inorganic cation homeostasis GO:0072503 127 0.029
regulation of protein transport GO:0051223 163 0.029
Yeast
nucleotide catabolic process GO:0009166 217 0.029
regulation of protein stability GO:0031647 52 0.029
lymphocyte mediated immunity GO:0002449 139 0.029
jnk cascade GO:0007254 72 0.029
nucleocytoplasmic transport GO:0006913 139 0.029
Yeast
lipid localization GO:0010876 126 0.029
Yeast
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.029
notch signaling pathway GO:0007219 71 0.029
cytokine production GO:0001816 319 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
positive regulation of lymphocyte activation GO:0051251 140 0.028
negative regulation of protein phosphorylation GO:0001933 126 0.028
protein localization to organelle GO:0033365 185 0.028
Yeast
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.028
striated muscle tissue development GO:0014706 293 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
heterocycle catabolic process GO:0046700 280 0.028
ion transmembrane transport GO:0034220 361 0.028
chemotaxis GO:0006935 247 0.027
chromatin organization GO:0006325 206 0.027
Yeast
regulation of transcription by galactose GO:0000409 1 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
nuclear division GO:0000280 158 0.027
Yeast
positive regulation of apoptotic signaling pathway GO:2001235 95 0.027
Human
regulation of homeostatic process GO:0032844 182 0.027
branching morphogenesis of an epithelial tube GO:0048754 159 0.026
leukocyte homeostasis GO:0001776 79 0.026
synaptic transmission GO:0007268 329 0.026
positive regulation of interleukin 8 production GO:0032757 2 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
nucleoside triphosphate catabolic process GO:0009143 205 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
microtubule based process GO:0007017 236 0.026
b cell homeostasis GO:0001782 34 0.026
rna processing GO:0006396 105 0.026
purine ribonucleotide biosynthetic process GO:0009152 59 0.026
skeletal system morphogenesis GO:0048705 203 0.026
dna alkylation GO:0006305 43 0.026
regulation of cell division GO:0051302 76 0.026
Yeast
purine containing compound metabolic process GO:0072521 311 0.025
negative regulation of cell migration GO:0030336 59 0.025
organelle assembly GO:0070925 177 0.025
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
muscle cell development GO:0055001 133 0.025
tor signaling GO:0031929 21 0.025
regulation of defense response GO:0031347 233 0.025
protein maturation GO:0051604 176 0.025
Human
positive regulation of nucleoside metabolic process GO:0045979 91 0.025
histone modification GO:0016570 159 0.025
Yeast
gliogenesis GO:0042063 141 0.025
respiratory system development GO:0060541 190 0.025
organophosphate catabolic process GO:0046434 232 0.025
purine containing compound catabolic process GO:0072523 213 0.025
axonogenesis GO:0007409 274 0.025
Mouse
multicellular organism growth GO:0035264 161 0.025
negative regulation of mapk cascade GO:0043409 65 0.024
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.024
multicellular organismal signaling GO:0035637 91 0.024
erythrocyte differentiation GO:0030218 88 0.024
lung development GO:0030324 164 0.024
central nervous system neuron differentiation GO:0021953 162 0.024
regulation of ras gtpase activity GO:0032318 88 0.024
cellular chemical homeostasis GO:0055082 215 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.024
protein import into nucleus GO:0006606 95 0.024
Yeast
lymphocyte differentiation GO:0030098 242 0.024
muscle tissue development GO:0060537 308 0.024
regulation of tor signaling GO:0032006 17 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
gastrulation GO:0007369 116 0.024
adaptive immune response GO:0002250 155 0.024
proteasomal protein catabolic process GO:0010498 98 0.024
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.024
neural tube closure GO:0001843 90 0.024
cognition GO:0050890 149 0.024
response to transforming growth factor beta GO:0071559 88 0.023
rac protein signal transduction GO:0016601 13 0.023
respiratory tube development GO:0030323 167 0.023
response to oxidative stress GO:0006979 123 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
Yeast
cyclic purine nucleotide metabolic process GO:0052652 43 0.023
regulation of map kinase activity GO:0043405 120 0.023
negative regulation of kinase activity GO:0033673 81 0.023
positive regulation of cell activation GO:0050867 158 0.023
positive regulation of glial cell proliferation GO:0060252 4 0.023
regulation of ion transport GO:0043269 215 0.023
regulation of hydrolase activity GO:0051336 246 0.022
Human
protein polyubiquitination GO:0000209 33 0.022
ameboidal type cell migration GO:0001667 128 0.022
cytokine mediated signaling pathway GO:0019221 115 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
interleukin 8 production GO:0032637 4 0.022
cellular response to molecule of bacterial origin GO:0071219 83 0.022
stem cell differentiation GO:0048863 268 0.022
regulation of inflammatory response GO:0050727 147 0.022
response to extracellular stimulus GO:0009991 127 0.022
regulation of ossification GO:0030278 112 0.022
regulation of lymphocyte apoptotic process GO:0070228 41 0.022
protein import GO:0017038 101 0.022
Yeast
blood circulation GO:0008015 195 0.022
epithelial cell morphogenesis GO:0003382 41 0.022
skin development GO:0043588 220 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
leukocyte proliferation GO:0070661 172 0.021
peptidyl tyrosine phosphorylation GO:0018108 143 0.021
Human
osteoclast differentiation GO:0030316 62 0.021
locomotory behavior GO:0007626 195 0.021
glycoprotein metabolic process GO:0009100 116 0.021
regulation of nucleotide biosynthetic process GO:0030808 34 0.021
epidermis development GO:0008544 187 0.021
positive regulation of neuron projection development GO:0010976 79 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.021
regulation of mitotic cell cycle GO:0007346 126 0.021
Yeast
regulation of nucleoside metabolic process GO:0009118 130 0.021
regulation of system process GO:0044057 200 0.021
purine containing compound biosynthetic process GO:0072522 70 0.021
forebrain development GO:0030900 302 0.020
gtp catabolic process GO:0006184 143 0.020
cellular ketone metabolic process GO:0042180 84 0.020
regulation of lymphocyte differentiation GO:0045619 107 0.020
dna methylation GO:0006306 43 0.020
circulatory system process GO:0003013 197 0.020
protein localization to membrane GO:0072657 108 0.020
Mouse
cell activation involved in immune response GO:0002263 126 0.020
cellular response to extracellular stimulus GO:0031668 81 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
Human
heart process GO:0003015 94 0.020
rhythmic process GO:0048511 174 0.020
t cell receptor signaling pathway GO:0050852 46 0.020
lymphocyte proliferation GO:0046651 164 0.020
visual learning GO:0008542 44 0.020
positive regulation of gtpase activity GO:0043547 85 0.020
regulation of cellular response to growth factor stimulus GO:0090287 82 0.020
cellular response to lipid GO:0071396 145 0.020
learning or memory GO:0007611 148 0.020
regulation of myeloid cell differentiation GO:0045637 96 0.020
establishment of glial blood brain barrier GO:0060857 2 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
cytosolic calcium ion homeostasis GO:0051480 70 0.020
cyclic nucleotide metabolic process GO:0009187 59 0.020
cellular amide metabolic process GO:0043603 58 0.020
primary neural tube formation GO:0014020 95 0.020
negative regulation of immune system process GO:0002683 209 0.020
embryonic organ morphogenesis GO:0048562 276 0.020
intracellular protein transport GO:0006886 204 0.020
Yeast
sensory perception GO:0007600 245 0.019
cytokinesis GO:0000910 17 0.019
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
terminal button organization GO:0072553 3 0.019
connective tissue development GO:0061448 179 0.019
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.019
development of primary sexual characteristics GO:0045137 143 0.019
Worm
t cell proliferation GO:0042098 120 0.019
alpha beta t cell activation GO:0046631 91 0.019
coagulation GO:0050817 78 0.019
cellular response to external stimulus GO:0071496 88 0.019
b cell activation GO:0042113 161 0.019
calcium mediated signaling GO:0019722 46 0.019
cardiac muscle contraction GO:0060048 32 0.019
positive regulation of cell motility GO:2000147 116 0.019
response to lipopolysaccharide GO:0032496 128 0.019
positive regulation of ras gtpase activity GO:0032320 65 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
Human
synaptic vesicle localization GO:0097479 59 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
Yeast
myosin filament organization GO:0031033 3 0.018
regulation of leukocyte apoptotic process GO:2000106 56 0.018
regulation of t cell differentiation GO:0045580 83 0.018
regulation of innate immune response GO:0045088 91 0.018
divalent metal ion transport GO:0070838 172 0.018
membrane lipid biosynthetic process GO:0046467 32 0.018
sphingolipid biosynthetic process GO:0030148 26 0.018
single organism cell adhesion GO:0098602 156 0.018
leukocyte apoptotic process GO:0071887 71 0.018
positive regulation of t cell activation GO:0050870 101 0.018
covalent chromatin modification GO:0016569 163 0.018
Yeast
innate immune response GO:0045087 157 0.018
angiogenesis GO:0001525 201 0.018
oxidation reduction process GO:0055114 342 0.018
small molecule biosynthetic process GO:0044283 132 0.018
negative regulation of map kinase activity GO:0043407 34 0.018
regulation of hormone levels GO:0010817 211 0.017
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.017
negative regulation of ossification GO:0030279 49 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
regulation of developmental pigmentation GO:0048070 14 0.017
regulation of heart contraction GO:0008016 77 0.017
transmission of nerve impulse GO:0019226 76 0.017
regulation of actin filament polymerization GO:0030833 38 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
positive regulation of protein export from nucleus GO:0046827 4 0.017
ossification GO:0001503 216 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
regulation of osteoblast differentiation GO:0045667 67 0.017
cellular response to oxidative stress GO:0034599 76 0.017
regulation of proteolysis GO:0030162 164 0.017
Human
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.017
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.017
cell adhesion GO:0007155 329 0.016
defense response to other organism GO:0098542 197 0.016
myeloid cell homeostasis GO:0002262 114 0.016
camera type eye development GO:0043010 266 0.016
sphingolipid metabolic process GO:0006665 45 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.016
response to nutrient levels GO:0031667 109 0.016
positive regulation of osteoclast differentiation GO:0045672 15 0.016
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
cell junction assembly GO:0034329 52 0.016
Worm
response to peptide GO:1901652 136 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
membrane lipid metabolic process GO:0006643 53 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
second messenger mediated signaling GO:0019932 73 0.016
calcium ion transport into cytosol GO:0060402 48 0.016
regulation of t cell proliferation GO:0042129 92 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
Human Yeast
cellular response to nutrient levels GO:0031669 64 0.016
calcium ion transport GO:0006816 159 0.016
regulation of body fluid levels GO:0050878 162 0.016
appendage development GO:0048736 166 0.016
positive regulation of organelle organization GO:0010638 128 0.016
regulation of vasculature development GO:1901342 88 0.016
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.016
sensory perception of sound GO:0007605 97 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
antigen receptor mediated signaling pathway GO:0050851 64 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
cell proliferation involved in heart valve development GO:2000793 2 0.016
negative regulation of organelle organization GO:0010639 90 0.015
digestive tract development GO:0048565 190 0.015
alcohol metabolic process GO:0006066 116 0.015
circadian rhythm GO:0007623 114 0.015
macromolecule methylation GO:0043414 120 0.015
response to alkaloid GO:0043279 34 0.015

Pak2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.137
disease of cellular proliferation DOID:14566 0 0.137
organ system cancer DOID:0050686 0 0.046
colon cancer DOID:219 0 0.033
colorectal cancer DOID:9256 0 0.033
gastrointestinal system cancer DOID:3119 0 0.033
intestinal cancer DOID:10155 0 0.033
large intestine cancer DOID:5672 0 0.033