Mus musculus

34 known processes

Pak3

p21 protein (Cdc42/Rac)-activated kinase 3

(Aliases: Stk4,PAK-3,Pak65alpha,Pak65beta,mPAK-3)

Pak3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.254
establishment of vesicle localization GO:0051650 81 0.155
regulation of cell projection organization GO:0031344 206 0.144
Rat
cellular amine metabolic process GO:0044106 44 0.141
striated muscle tissue development GO:0014706 293 0.135
regulation of cellular ketone metabolic process GO:0010565 66 0.129
microtubule based process GO:0007017 236 0.117
establishment of organelle localization GO:0051656 122 0.114
locomotory behavior GO:0007626 195 0.109
amine metabolic process GO:0009308 45 0.099
spermatid differentiation GO:0048515 115 0.093
negative regulation of nervous system development GO:0051961 156 0.093
nitrogen compound transport GO:0071705 271 0.091
learning or memory GO:0007611 148 0.089
regulation of neuron apoptotic process GO:0043523 122 0.088
Rat
regulation of cellular component size GO:0032535 121 0.086
Human
axonogenesis GO:0007409 274 0.084
apoptotic signaling pathway GO:0097190 306 0.081
positive regulation of protein modification process GO:0031401 299 0.081
Human Yeast
cell type specific apoptotic process GO:0097285 268 0.079
Rat
muscle tissue development GO:0060537 308 0.079
intracellular protein transport GO:0006886 204 0.078
Yeast
sensory perception GO:0007600 245 0.077
gland development GO:0048732 330 0.077
positive regulation of nervous system development GO:0051962 221 0.076
Rat
cellular ketone metabolic process GO:0042180 84 0.075
cellular amino acid metabolic process GO:0006520 103 0.074
organelle localization GO:0051640 179 0.074
microtubule based movement GO:0007018 84 0.074
regulation of organelle organization GO:0033043 289 0.073
Human Yeast
calcium ion homeostasis GO:0055074 127 0.073
regulation of cellular amino acid metabolic process GO:0006521 5 0.071
negative regulation of neuron death GO:1901215 98 0.070
positive regulation of cellular amine metabolic process GO:0033240 5 0.070
regulation of neuron projection development GO:0010975 169 0.070
Rat
sensory organ morphogenesis GO:0090596 242 0.067
peripheral nervous system neuron axonogenesis GO:0048936 3 0.067
positive regulation of apoptotic process GO:0043065 217 0.066
Yeast Rat
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.066
negative regulation of cellular component organization GO:0051129 194 0.065
neuron death GO:0070997 154 0.065
Rat
exocytosis GO:0006887 121 0.065
axon guidance GO:0007411 141 0.065
regulation of anatomical structure size GO:0090066 178 0.065
Human
skeletal system development GO:0001501 356 0.063
vesicle localization GO:0051648 86 0.063
microtubule cytoskeleton organization GO:0000226 157 0.063
rap protein signal transduction GO:0032486 3 0.062
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.062
learning GO:0007612 98 0.061
negative regulation of neuron projection development GO:0010977 50 0.060
cellular lipid metabolic process GO:0044255 323 0.060
camera type eye development GO:0043010 266 0.059
adult locomotory behavior GO:0008344 91 0.059
appendage development GO:0048736 166 0.058
cell adhesion GO:0007155 329 0.058
regulation of neuron death GO:1901214 134 0.057
Rat
stem cell differentiation GO:0048863 268 0.056
membrane organization GO:0061024 245 0.056
Mouse
regulation of kinase activity GO:0043549 249 0.054
Human Yeast
organelle assembly GO:0070925 177 0.054
Yeast
positive regulation of mapk cascade GO:0043410 170 0.053
Human Yeast
cellular chemical homeostasis GO:0055082 215 0.051
leukocyte differentiation GO:0002521 342 0.051
positive regulation of kinase activity GO:0033674 155 0.050
Human Yeast
ear morphogenesis GO:0042471 118 0.049
spermatid development GO:0007286 108 0.049
limbic system development GO:0021761 72 0.049
regulation of secretion by cell GO:1903530 249 0.049
positive regulation of neuron differentiation GO:0045666 141 0.048
Rat
positive regulation of cell development GO:0010720 237 0.048
Rat
g protein coupled receptor signaling pathway GO:0007186 243 0.047
Yeast
regulation of protein kinase activity GO:0045859 232 0.047
Human Yeast
maintenance of presynaptic active zone structure GO:0048790 1 0.047
stem cell development GO:0048864 219 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.046
single organism cell adhesion GO:0098602 156 0.046
regulation of exocytosis GO:0017157 61 0.046
adult behavior GO:0030534 135 0.046
compound eye development GO:0048749 1 0.046
negative regulation of cell development GO:0010721 169 0.045
male gamete generation GO:0048232 285 0.045
neuron apoptotic process GO:0051402 142 0.045
Rat
regulation of mapk cascade GO:0043408 248 0.045
Human Yeast
embryonic organ morphogenesis GO:0048562 276 0.044
ear development GO:0043583 200 0.043
angiogenesis GO:0001525 201 0.043
sensory perception of mechanical stimulus GO:0050954 107 0.043
regulation of neuron differentiation GO:0045664 281 0.043
Rat
actin cytoskeleton organization GO:0030036 220 0.042
Human
tube closure GO:0060606 91 0.042
neuron neuron synaptic transmission GO:0007270 69 0.042
cellular homeostasis GO:0019725 240 0.042
regulation of cell motility GO:2000145 236 0.042
regulation of hormone levels GO:0010817 211 0.041
microtubule polymerization or depolymerization GO:0031109 26 0.041
mitochondrion transport along microtubule GO:0047497 3 0.041
cell fate commitment GO:0045165 210 0.041
regulation of secretion GO:0051046 274 0.040
ion transmembrane transport GO:0034220 361 0.039
neural precursor cell proliferation GO:0061351 121 0.038
regulation of transferase activity GO:0051338 263 0.038
Human Yeast
macromolecule catabolic process GO:0009057 281 0.037
response to organonitrogen compound GO:0010243 246 0.037
regulation of intracellular transport GO:0032386 159 0.037
Yeast
metal ion homeostasis GO:0055065 189 0.036
protein localization to organelle GO:0033365 185 0.036
Yeast
fasciculation of sensory neuron axon GO:0097155 3 0.036
rac protein signal transduction GO:0016601 13 0.036
mechanoreceptor differentiation GO:0042490 67 0.035
regulation of synaptic plasticity GO:0048167 87 0.035
developmental growth involved in morphogenesis GO:0060560 138 0.035
olfactory learning GO:0008355 2 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
Human
anion transport GO:0006820 177 0.035
positive regulation of programmed cell death GO:0043068 218 0.035
Yeast Rat
mitotic cell cycle GO:0000278 195 0.035
Yeast
forebrain development GO:0030900 302 0.034
regulation of cell adhesion GO:0030155 154 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
Human Yeast
regulation of cell cycle GO:0051726 281 0.034
Yeast
positive regulation of cell death GO:0010942 224 0.034
Yeast Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.033
cognition GO:0050890 149 0.033
divalent inorganic cation homeostasis GO:0072507 138 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
negative regulation of neuron differentiation GO:0045665 101 0.032
regulation of vasculature development GO:1901342 88 0.032
regulation of microtubule based process GO:0032886 52 0.032
regulation of apoptotic signaling pathway GO:2001233 197 0.031
neuron projection guidance GO:0097485 141 0.031
insulin secretion GO:0030073 89 0.031
cytokine production GO:0001816 319 0.031
mrna metabolic process GO:0016071 84 0.031
mitotic cell cycle process GO:1903047 159 0.031
Yeast
pole plasm assembly GO:0007315 2 0.030
response to radiation GO:0009314 165 0.030
thymus development GO:0048538 41 0.030
negative regulation of neuron projection regeneration GO:0070571 3 0.030
amide transport GO:0042886 138 0.030
negative regulation of cell proliferation GO:0008285 296 0.030
response to growth factor GO:0070848 198 0.030
regulation of protein serine threonine kinase activity GO:0071900 157 0.029
Human Yeast
regulation of protein localization GO:0032880 231 0.029
Yeast
t cell activation GO:0042110 289 0.029
limb development GO:0060173 166 0.029
gonad development GO:0008406 141 0.029
Worm
peptidyl amino acid modification GO:0018193 336 0.029
Yeast
regulation of cytoskeleton organization GO:0051493 122 0.029
Human
neurotransmitter transport GO:0006836 76 0.029
translation GO:0006412 93 0.029
endomembrane system organization GO:0010256 147 0.029
calcium ion dependent exocytosis GO:0017156 35 0.029
response to light stimulus GO:0009416 135 0.029
protein targeting GO:0006605 143 0.029
Yeast
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.028
oocyte axis specification GO:0007309 2 0.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.028
respiratory tube development GO:0030323 167 0.028
lymphocyte differentiation GO:0030098 242 0.028
regulation of feeding behavior GO:0060259 3 0.028
cation homeostasis GO:0055080 212 0.028
appendage morphogenesis GO:0035107 149 0.028
regulation of translation GO:0006417 71 0.027
negative regulation of molecular function GO:0044092 258 0.027
establishment of mitochondrion localization GO:0051654 4 0.027
epidermis development GO:0008544 187 0.027
hormone secretion GO:0046879 128 0.027
cell division GO:0051301 120 0.027
Yeast
regulation of vesicle mediated transport GO:0060627 139 0.027
nucleotide metabolic process GO:0009117 332 0.027
regulation of membrane potential GO:0042391 192 0.027
establishment of protein localization to organelle GO:0072594 118 0.026
Yeast
regulation of neuronal synaptic plasticity GO:0048168 30 0.026
protein processing GO:0016485 163 0.026
negative regulation of organelle organization GO:0010639 90 0.026
microtubule sliding GO:0051012 1 0.026
synaptic vesicle localization GO:0097479 59 0.026
chemotaxis GO:0006935 247 0.025
cytoskeleton dependent intracellular transport GO:0030705 50 0.025
urogenital system development GO:0001655 261 0.025
positive regulation of apoptotic signaling pathway GO:2001235 95 0.025
skeletal muscle organ development GO:0060538 163 0.025
cellular protein complex assembly GO:0043623 116 0.025
Human
rna splicing GO:0008380 54 0.025
morphogenesis of embryonic epithelium GO:0016331 159 0.025
protein polymerization GO:0051258 57 0.025
Human
gliogenesis GO:0042063 141 0.025
multicellular organismal signaling GO:0035637 91 0.025
negative regulation of ovulation GO:0060280 1 0.025
protein complex disassembly GO:0043241 40 0.025
rna splicing via transesterification reactions GO:0000375 43 0.025
male sex differentiation GO:0046661 109 0.025
action potential GO:0001508 78 0.025
regulation of stem cell differentiation GO:2000736 50 0.024
positive regulation of neuron projection development GO:0010976 79 0.024
Rat
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.024
response to monosaccharide GO:0034284 67 0.024
mitochondrion organization GO:0007005 134 0.024
bone development GO:0060348 120 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
limb morphogenesis GO:0035108 149 0.024
cellular response to external stimulus GO:0071496 88 0.024
establishment or maintenance of cell polarity GO:0007163 86 0.024
Yeast
myeloid cell differentiation GO:0030099 233 0.024
cartilage development GO:0051216 140 0.024
homeostasis of number of cells GO:0048872 210 0.024
innate immune response GO:0045087 157 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
rhythmic process GO:0048511 174 0.024
male gonad development GO:0008584 88 0.024
ameboidal type cell migration GO:0001667 128 0.024
epithelial tube morphogenesis GO:0060562 303 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
development of primary male sexual characteristics GO:0046546 88 0.023
positive regulation of protein kinase activity GO:0045860 144 0.023
Human Yeast
cellular metal ion homeostasis GO:0006875 151 0.023
peptide hormone secretion GO:0030072 109 0.023
regulation of wnt signaling pathway GO:0030111 123 0.023
neural tube development GO:0021915 160 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
regulation of neurotransmitter levels GO:0001505 87 0.023
fertilization GO:0009566 127 0.023
spermatogenesis GO:0007283 284 0.023
regulation of hydrolase activity GO:0051336 246 0.023
b cell activation GO:0042113 161 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
central nervous system neuron differentiation GO:0021953 162 0.023
morphogenesis of a branching structure GO:0001763 203 0.023
oocyte construction GO:0007308 2 0.022
negative regulation of neuron apoptotic process GO:0043524 92 0.022
sensory perception of sound GO:0007605 97 0.022
digestive tract morphogenesis GO:0048546 147 0.022
palate development GO:0060021 76 0.022
ras protein signal transduction GO:0007265 77 0.022
dendrite development GO:0016358 115 0.022
regulation of peptide hormone secretion GO:0090276 75 0.022
cardiac muscle tissue development GO:0048738 130 0.022
vesicle organization GO:0016050 60 0.022
rna processing GO:0006396 105 0.022
peptide transport GO:0015833 133 0.022
aromatic compound catabolic process GO:0019439 286 0.022
synaptic transmission glycinergic GO:0060012 2 0.022
cell recognition GO:0008037 83 0.022
stress activated protein kinase signaling cascade GO:0031098 81 0.022
digestive tract development GO:0048565 190 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.021
regulation of cell migration GO:0030334 219 0.021
microtubule based transport GO:0010970 50 0.021
embryonic skeletal system development GO:0048706 120 0.021
synaptic vesicle priming GO:0016082 8 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
cellular response to starvation GO:0009267 57 0.021
associative learning GO:0008306 61 0.021
cell junction organization GO:0034330 77 0.021
Worm
transmembrane transport GO:0055085 412 0.021
Yeast
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
morphogenesis of a branching epithelium GO:0061138 193 0.020
regulation of cytokine production GO:0001817 266 0.020
mitotic cytokinesis GO:0000281 4 0.020
Yeast
regulation of response to drug GO:2001023 2 0.020
nucleoside metabolic process GO:0009116 246 0.020
establishment of glial blood brain barrier GO:0060857 2 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
nuclear transport GO:0051169 139 0.020
Yeast
neuron migration GO:0001764 122 0.020
development of primary sexual characteristics GO:0045137 143 0.020
Worm
positive regulation of cell motility GO:2000147 116 0.020
axonal fasciculation GO:0007413 15 0.020
germ cell development GO:0007281 185 0.020
negative regulation of protein metabolic process GO:0051248 282 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
regulation of response to wounding GO:1903034 189 0.019
response to peptide hormone GO:0043434 127 0.019
regulation of ovulation GO:0060278 3 0.019
embryonic limb morphogenesis GO:0030326 126 0.019
male anatomical structure morphogenesis GO:0090598 4 0.019
inner ear morphogenesis GO:0042472 101 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
positive regulation of cell adhesion GO:0045785 80 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
cellular ion homeostasis GO:0006873 165 0.019
oligodendrocyte differentiation GO:0048709 53 0.019
rhodopsin mediated signaling pathway GO:0016056 4 0.019
retrograde transport endosome to golgi GO:0042147 2 0.019
establishment of synaptic vesicle localization GO:0097480 57 0.019
carbohydrate homeostasis GO:0033500 128 0.019
regulation of multi organism process GO:0043900 111 0.019
regeneration GO:0031099 38 0.019
regulation of rna splicing GO:0043484 37 0.019
notochord cell development GO:0060035 1 0.019
branching morphogenesis of an epithelial tube GO:0048754 159 0.019
regulation of body fluid levels GO:0050878 162 0.019
single organism nuclear import GO:1902593 95 0.019
Yeast
regulation of cellular catabolic process GO:0031329 242 0.019
multicellular organism growth GO:0035264 161 0.019
organelle fission GO:0048285 170 0.019
Yeast
second messenger mediated signaling GO:0019932 73 0.019
skin development GO:0043588 220 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
female sex differentiation GO:0046660 84 0.019
neuronal action potential GO:0019228 54 0.019
regulation of mrna processing GO:0050684 41 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
Yeast
epithelial cell development GO:0002064 159 0.018
regulation of nucleocytoplasmic transport GO:0046822 73 0.018
Yeast
regulation of cell growth GO:0001558 91 0.018
cell growth GO:0016049 130 0.018
Yeast
synaptic transmission cholinergic GO:0007271 7 0.018
neuron projection extension GO:1990138 64 0.018
glial cell differentiation GO:0010001 131 0.018
phospholipid metabolic process GO:0006644 87 0.018
developmental maturation GO:0021700 193 0.018
lipid biosynthetic process GO:0008610 179 0.018
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.018
jnk cascade GO:0007254 72 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
protein maturation GO:0051604 176 0.018
blood vessel morphogenesis GO:0048514 285 0.018
negative regulation of synapse assembly GO:0051964 3 0.018
cellularization GO:0007349 1 0.018
heterocycle catabolic process GO:0046700 280 0.018
cytokine mediated signaling pathway GO:0019221 115 0.018
peptide secretion GO:0002790 114 0.017
body morphogenesis GO:0010171 45 0.017
Worm
mrna processing GO:0006397 63 0.017
negative regulation of cell projection organization GO:0031345 56 0.017
female gonad development GO:0008585 71 0.017
dna metabolic process GO:0006259 303 0.017
Rat
sa node cell action potential GO:0086015 4 0.017
b cell differentiation GO:0030183 78 0.017
organic anion transport GO:0015711 137 0.017
multicellular organismal response to stress GO:0033555 62 0.017
mrna splicing via spliceosome GO:0000398 43 0.017
regulation of microtubule cytoskeleton organization GO:0070507 37 0.017
neuromuscular process GO:0050905 99 0.017
inner ear receptor cell differentiation GO:0060113 61 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
regulation of protein complex assembly GO:0043254 83 0.017
Human
single fertilization GO:0007338 82 0.017
canonical wnt signaling pathway GO:0060070 130 0.017
erythrocyte differentiation GO:0030218 88 0.017
maternal determination of anterior posterior axis embryo GO:0008358 2 0.016
cytoplasmic transport GO:0016482 234 0.016
Yeast
stem cell maintenance GO:0019827 130 0.016
digestive system development GO:0055123 200 0.016
regulation of angiogenesis GO:0045765 81 0.016
regulation of gliogenesis GO:0014013 50 0.016
chloride transmembrane transport GO:1902476 24 0.016
rho protein signal transduction GO:0007266 32 0.016
fat cell differentiation GO:0045444 160 0.016
positive regulation of creb transcription factor activity GO:0032793 4 0.016
mapk cascade GO:0000165 281 0.016
Human Yeast
stress activated mapk cascade GO:0051403 80 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
Yeast
mesenchyme development GO:0060485 152 0.016
response to acid chemical GO:0001101 111 0.016
immune effector process GO:0002252 321 0.016
asymmetric neuroblast division GO:0055059 1 0.016
positive regulation of cell migration GO:0030335 109 0.016
regulation of smoothened signaling pathway GO:0008589 58 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
asymmetric stem cell division GO:0098722 3 0.016
glycerolipid metabolic process GO:0046486 122 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
positive regulation of organelle organization GO:0010638 128 0.016
wnt signaling pathway GO:0016055 188 0.016
regulation of dendritic spine morphogenesis GO:0061001 17 0.016
Rat
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.016
retina development in camera type eye GO:0060041 119 0.016
negative regulation of cytoskeleton organization GO:0051494 36 0.016
organ growth GO:0035265 117 0.016
neuron maturation GO:0042551 29 0.016
protein localization to nucleus GO:0034504 121 0.016
Yeast
positive regulation of map kinase activity GO:0043406 84 0.016
Human
positive regulation of secretion by cell GO:1903532 114 0.016
synaptic vesicle transport GO:0048489 57 0.016
regulation of defense response GO:0031347 233 0.016
skeletal system morphogenesis GO:0048705 203 0.015
negative regulation of phospholipase activity GO:0010519 4 0.015
protein catabolic process GO:0030163 221 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
regulation of mrna metabolic process GO:1903311 43 0.015
regulation of protein catabolic process GO:0042176 108 0.015
extracellular structure organization GO:0043062 148 0.015
anatomical structure homeostasis GO:0060249 145 0.015
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.015
regulation of stress activated mapk cascade GO:0032872 69 0.015
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
microtubule nucleation GO:0007020 2 0.015
regulation of cell size GO:0008361 72 0.015
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
respiratory system development GO:0060541 190 0.015
intracellular mrna localization GO:0008298 4 0.015
endocytosis GO:0006897 168 0.015
primary neural tube formation GO:0014020 95 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
actin polymerization or depolymerization GO:0008154 54 0.015
Human
circadian regulation of gene expression GO:0032922 48 0.015
mitochondrion distribution GO:0048311 4 0.015
regulation of proteolysis GO:0030162 164 0.015
acetate ester transport GO:1901374 2 0.015
response to extracellular stimulus GO:0009991 127 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
neurotransmitter secretion GO:0007269 62 0.015
negative regulation of cell cycle GO:0045786 123 0.014
hippocampus development GO:0021766 52 0.014
macromolecular complex disassembly GO:0032984 43 0.014
hindbrain development GO:0030902 128 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
negative regulation of protein depolymerization GO:1901880 21 0.014
regulation of axon diameter GO:0031133 6 0.014
telencephalon development GO:0021537 186 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
regulation of cellular response to stress GO:0080135 159 0.014
mesenchymal cell differentiation GO:0048762 107 0.014
regulation of map kinase activity GO:0043405 120 0.014
Human
heart morphogenesis GO:0003007 178 0.014
embryonic appendage morphogenesis GO:0035113 126 0.014
regulation of peptidase activity GO:0052547 96 0.014
epithelial cell proliferation GO:0050673 174 0.014
male courtship behavior GO:0008049 2 0.014
regulation of ion transport GO:0043269 215 0.014
peripheral nervous system axon regeneration GO:0014012 2 0.014
actin filament organization GO:0007015 113 0.014
Human
cellular response to organonitrogen compound GO:0071417 145 0.014
transcription from rna polymerase iii promoter GO:0006383 3 0.014
positive regulation of schwann cell proliferation GO:0010625 1 0.014
cardiac cell fate specification GO:0060912 2 0.014
epithelium migration GO:0090132 63 0.014
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.014
regulation of circadian rhythm GO:0042752 58 0.014
positive regulation of necrotic cell death GO:0010940 1 0.014
regulation of peptide transport GO:0090087 91 0.014
regulation of protein depolymerization GO:1901879 26 0.013
response to histamine GO:0034776 1 0.013
cell cell signaling involved in lung development GO:0060495 1 0.013
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.013
multi organism behavior GO:0051705 62 0.013
maintenance of location GO:0051235 89 0.013
defecation GO:0030421 1 0.013
synapse organization GO:0050808 125 0.013
Mouse
circadian rhythm GO:0007623 114 0.013
cellular response to carbohydrate stimulus GO:0071322 50 0.013
oxidation reduction process GO:0055114 342 0.013
transmission of nerve impulse GO:0019226 76 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
Human Yeast
inner ear receptor cell development GO:0060119 39 0.013
leukocyte migration GO:0050900 124 0.013
chromatin organization GO:0006325 206 0.013
Yeast
regulation of leukocyte differentiation GO:1902105 159 0.013
intracellular receptor signaling pathway GO:0030522 74 0.013
bmp signaling pathway GO:0030509 93 0.013
positive regulation of translation GO:0045727 19 0.013
regulation of system process GO:0044057 200 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
Yeast
cellular response to extracellular stimulus GO:0031668 81 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
glucose homeostasis GO:0042593 128 0.013
regionalization GO:0003002 337 0.013
regulation of jnk cascade GO:0046328 62 0.013
regulation of peptide secretion GO:0002791 77 0.013
wound healing GO:0042060 157 0.013
actin filament polymerization GO:0030041 44 0.013
Human
nerve development GO:0021675 67 0.013
cell junction assembly GO:0034329 52 0.013
Worm
synaptic transmission glutamatergic GO:0035249 36 0.013
photoreceptor cell maintenance GO:0045494 19 0.013
nuclear division GO:0000280 158 0.013
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
epithelial cell migration GO:0010631 63 0.013
lipid modification GO:0030258 65 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
regulation of cell substrate adhesion GO:0010810 73 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.012
regulation of cell cycle process GO:0010564 160 0.012
Yeast
developmental cell growth GO:0048588 84 0.012
positive regulation of growth GO:0045927 104 0.012
response to steroid hormone GO:0048545 56 0.012
regulation of voltage gated calcium channel activity GO:1901385 4 0.012
sensory perception of light stimulus GO:0050953 54 0.012
membrane tubulation GO:0097320 4 0.012

Pak3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
neuropathy DOID:870 0 0.017
musculoskeletal system disease DOID:17 0 0.015