Mus musculus

66 known processes

Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

(Aliases: Pak5,6430627N20,2900083L08Rik,MGC117585)

Pak7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.085
regulation of membrane potential GO:0042391 192 0.082
regulation of neuron differentiation GO:0045664 281 0.067
Fly
synapse organization GO:0050808 125 0.067
cellular amine metabolic process GO:0044106 44 0.064
synaptic transmission GO:0007268 329 0.062
retina development in camera type eye GO:0060041 119 0.061
locomotory behavior GO:0007626 195 0.059
cell adhesion GO:0007155 329 0.055
Fly
purine nucleotide metabolic process GO:0006163 302 0.053
regulation of secretion by cell GO:1903530 249 0.051
ribonucleotide metabolic process GO:0009259 291 0.049
metal ion homeostasis GO:0055065 189 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.046
regulation of secretion GO:0051046 274 0.046
central nervous system neuron differentiation GO:0021953 162 0.044
nucleotide metabolic process GO:0009117 332 0.042
cation homeostasis GO:0055080 212 0.041
inorganic cation transmembrane transport GO:0098662 207 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.037
positive regulation of nervous system development GO:0051962 221 0.036
Fly
endocytosis GO:0006897 168 0.036
dendrite development GO:0016358 115 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
amine metabolic process GO:0009308 45 0.035
ion transmembrane transport GO:0034220 361 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
purine containing compound metabolic process GO:0072521 311 0.034
multicellular organismal signaling GO:0035637 91 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
regulation of protein kinase activity GO:0045859 232 0.033
regulation of cellular component biogenesis GO:0044087 181 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
heterocycle catabolic process GO:0046700 280 0.033
organelle localization GO:0051640 179 0.033
positive regulation of protein modification process GO:0031401 299 0.032
regulation of protein serine threonine kinase activity GO:0071900 157 0.032
forebrain development GO:0030900 302 0.031
transmission of nerve impulse GO:0019226 76 0.031
establishment of organelle localization GO:0051656 122 0.031
positive regulation of cell development GO:0010720 237 0.031
Fly
regulation of vesicle mediated transport GO:0060627 139 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.031
cellular amino acid metabolic process GO:0006520 103 0.030
membrane organization GO:0061024 245 0.030
cellular homeostasis GO:0019725 240 0.029
single organism cell adhesion GO:0098602 156 0.029
Fly
regulation of map kinase activity GO:0043405 120 0.029
synaptic transmission glutamatergic GO:0035249 36 0.028
regulation of neuron projection development GO:0010975 169 0.028
rap protein signal transduction GO:0032486 3 0.028
endomembrane system organization GO:0010256 147 0.027
Fly
regulation of cell projection organization GO:0031344 206 0.027
exocytosis GO:0006887 121 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
camera type eye development GO:0043010 266 0.027
neural precursor cell proliferation GO:0061351 121 0.026
transmembrane transport GO:0055085 412 0.026
axonogenesis GO:0007409 274 0.026
positive regulation of protein phosphorylation GO:0001934 242 0.026
regulation of transferase activity GO:0051338 263 0.026
negative regulation of cell development GO:0010721 169 0.026
regulation of organelle organization GO:0033043 289 0.026
calcium ion homeostasis GO:0055074 127 0.025
actin cytoskeleton organization GO:0030036 220 0.025
cation transmembrane transport GO:0098655 266 0.025
protein localization to membrane GO:0072657 108 0.025
action potential GO:0001508 78 0.024
negative regulation of bone trabecula formation GO:1900155 1 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
positive regulation of map kinase activity GO:0043406 84 0.024
regulation of ion transport GO:0043269 215 0.024
anion transport GO:0006820 177 0.024
regulation of transmembrane transport GO:0034762 128 0.024
regulation of mapk cascade GO:0043408 248 0.023
nucleoside metabolic process GO:0009116 246 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
positive regulation of transferase activity GO:0051347 167 0.023
regulation of exocytosis GO:0017157 61 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
myeloid cell homeostasis GO:0002262 114 0.023
regulation of cell adhesion GO:0030155 154 0.023
Fly
synapse assembly GO:0007416 56 0.023
positive regulation of protein kinase activity GO:0045860 144 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
mapk cascade GO:0000165 281 0.022
skeletal system development GO:0001501 356 0.022
protein secretion GO:0009306 111 0.022
immune effector process GO:0002252 321 0.022
calcium ion transmembrane transport GO:0070588 85 0.022
regulation of hydrolase activity GO:0051336 246 0.022
cellular ketone metabolic process GO:0042180 84 0.022
ras protein signal transduction GO:0007265 77 0.021
homeostasis of number of cells GO:0048872 210 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
learning or memory GO:0007611 148 0.021
regulation of synaptic plasticity GO:0048167 87 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.021
cellularization GO:0007349 1 0.021
peptide hormone secretion GO:0030072 109 0.021
activation of mapk activity GO:0000187 59 0.021
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
nitrogen compound transport GO:0071705 271 0.021
regulation of cell motility GO:2000145 236 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
ribose phosphate metabolic process GO:0019693 291 0.020
notochord cell development GO:0060035 1 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
establishment of vesicle localization GO:0051650 81 0.020
gtp metabolic process GO:0046039 144 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
cognition GO:0050890 149 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
apoptotic signaling pathway GO:0097190 306 0.020
aromatic compound catabolic process GO:0019439 286 0.020
adult behavior GO:0030534 135 0.020
immune response regulating signaling pathway GO:0002764 125 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
nucleoside catabolic process GO:0009164 206 0.020
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
multicellular organism growth GO:0035264 161 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
microtubule based process GO:0007017 236 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
morphogenesis of a branching structure GO:0001763 203 0.019
negative regulation of immune system process GO:0002683 209 0.019
stem cell differentiation GO:0048863 268 0.019
divalent metal ion transport GO:0070838 172 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.018
chemotaxis GO:0006935 247 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
neural tube development GO:0021915 160 0.018
dephosphorylation GO:0016311 129 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
regulation of protein transport GO:0051223 163 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
nucleotide catabolic process GO:0009166 217 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
regulation of leukocyte differentiation GO:1902105 159 0.017
regulation of cell migration GO:0030334 219 0.017
negative regulation of protein modification process GO:0031400 163 0.017
cellular chemical homeostasis GO:0055082 215 0.017
regulation of feeding behavior GO:0060259 3 0.017
maternal determination of anterior posterior axis embryo GO:0008358 2 0.017
negative regulation of molecular function GO:0044092 258 0.017
regulation of neuron death GO:1901214 134 0.017
cell growth GO:0016049 130 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
regulation of multi organism process GO:0043900 111 0.017
fatty acid metabolic process GO:0006631 121 0.017
t cell activation GO:0042110 289 0.017
adult locomotory behavior GO:0008344 91 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.016
regulation of cytokine production GO:0001817 266 0.016
neuron projection guidance GO:0097485 141 0.016
divalent inorganic cation transport GO:0072511 178 0.016
central nervous system neuron development GO:0021954 67 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
neuron migration GO:0001764 122 0.016
cellular response to lipid GO:0071396 145 0.016
regulation of kinase activity GO:0043549 249 0.016
neurotransmitter transport GO:0006836 76 0.016
neuronal action potential GO:0019228 54 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
regulation of glutamate receptor signaling pathway GO:1900449 16 0.016
cell type specific apoptotic process GO:0097285 268 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
synaptic vesicle localization GO:0097479 59 0.016
membrane depolarization GO:0051899 64 0.015
axon ensheathment GO:0008366 76 0.015
telencephalon development GO:0021537 186 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
organophosphate catabolic process GO:0046434 232 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
cytokine production GO:0001816 319 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
neuromuscular process GO:0050905 99 0.015
adult walking behavior GO:0007628 41 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
positive regulation of kinase activity GO:0033674 155 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
plasma membrane organization GO:0007009 90 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.015
retina morphogenesis in camera type eye GO:0060042 45 0.015
anatomical structure homeostasis GO:0060249 145 0.015
detection of external stimulus GO:0009581 61 0.015
positive regulation of secretion GO:0051047 130 0.015
memory GO:0007613 58 0.014
glucose homeostasis GO:0042593 128 0.014
regulation of proteolysis GO:0030162 164 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
glutamate receptor signaling pathway GO:0007215 35 0.014
cellular lipid metabolic process GO:0044255 323 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
feeding behavior GO:0007631 62 0.014
amino acid transport GO:0006865 61 0.014
protein maturation GO:0051604 176 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
Fly
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
sensory perception of light stimulus GO:0050953 54 0.014
purine containing compound catabolic process GO:0072523 213 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
glial cell differentiation GO:0010001 131 0.014
protein ubiquitination GO:0016567 171 0.014
response to organonitrogen compound GO:0010243 246 0.014
protein localization to synapse GO:0035418 11 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
cell fate commitment GO:0045165 210 0.014
Fly
response to lipopolysaccharide GO:0032496 128 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
leukocyte differentiation GO:0002521 342 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
peptide secretion GO:0002790 114 0.013
inter male aggressive behavior GO:0002121 3 0.013
protein localization to juxtaparanode region of axon GO:0071205 4 0.013
regulation of cellular component size GO:0032535 121 0.013
Fly
regulation of neuronal synaptic plasticity GO:0048168 30 0.013
central nervous system projection neuron axonogenesis GO:0021952 21 0.013
peptidyl amino acid modification GO:0018193 336 0.013
Fly
learning GO:0007612 98 0.013
muscle tissue development GO:0060537 308 0.013
defecation GO:0030421 1 0.013
regulation of response to wounding GO:1903034 189 0.013
lateral line system development GO:0048925 1 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
lateral inhibition GO:0046331 1 0.013
Fly
negative regulation of organelle organization GO:0010639 90 0.013
vesicle localization GO:0051648 86 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
Fly
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
cell substrate adhesion GO:0031589 130 0.013
gland development GO:0048732 330 0.013
cell activation involved in immune response GO:0002263 126 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
insulin secretion GO:0030073 89 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
protein catabolic process GO:0030163 221 0.012
organic anion transport GO:0015711 137 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
regulation of protein localization GO:0032880 231 0.012
intracellular protein transport GO:0006886 204 0.012
lymphocyte differentiation GO:0030098 242 0.012
spermatogenesis GO:0007283 284 0.012
rna processing GO:0006396 105 0.012
regulation of cell size GO:0008361 72 0.012
Fly
stem cell development GO:0048864 219 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
rho protein signal transduction GO:0007266 32 0.012
sensory organ morphogenesis GO:0090596 242 0.012
Fly
neural tube closure GO:0001843 90 0.012
sensory perception of pain GO:0019233 47 0.012
oocyte construction GO:0007308 2 0.012
central nervous system neuron axonogenesis GO:0021955 28 0.012
myeloid cell differentiation GO:0030099 233 0.012
dorsal ventral axon guidance GO:0033563 3 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
erythrocyte differentiation GO:0030218 88 0.012
cell recognition GO:0008037 83 0.012
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of system process GO:0044057 200 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
regulation of glial cell differentiation GO:0045685 41 0.012
immune response activating signal transduction GO:0002757 116 0.012
axoneme assembly GO:0035082 15 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
detection of stimulus involved in sensory perception GO:0050906 44 0.012
cation transport GO:0006812 399 0.011
negative regulation of secretion by cell GO:1903531 54 0.011
compound eye development GO:0048749 1 0.011
Fly
positive regulation of secretion by cell GO:1903532 114 0.011
regulation of protein catabolic process GO:0042176 108 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
regulation of homeostatic process GO:0032844 182 0.011
oxidation reduction process GO:0055114 342 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
protein processing GO:0016485 163 0.011
axon guidance GO:0007411 141 0.011
eye photoreceptor cell differentiation GO:0001754 41 0.011
Fly
carboxylic acid transport GO:0046942 100 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
skin development GO:0043588 220 0.011
synaptic vesicle transport GO:0048489 57 0.011
neuromuscular process controlling balance GO:0050885 59 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
negative regulation of neuron projection regeneration GO:0070571 3 0.011
cellular ion homeostasis GO:0006873 165 0.011
gliogenesis GO:0042063 141 0.011
neural retina development GO:0003407 41 0.011
ensheathment of neurons GO:0007272 76 0.011
striated muscle tissue development GO:0014706 293 0.011
sensory perception GO:0007600 245 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
maintenance of location GO:0051235 89 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
Fly
organelle fission GO:0048285 170 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
eye photoreceptor cell development GO:0042462 31 0.011
Fly
photoreceptor cell maintenance GO:0045494 19 0.011
calcium ion transport GO:0006816 159 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
fat cell differentiation GO:0045444 160 0.011
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
cellular response to abiotic stimulus GO:0071214 56 0.010
regulation of body fluid levels GO:0050878 162 0.010
regionalization GO:0003002 337 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
negative regulation of nervous system development GO:0051961 156 0.010
regulation of gliogenesis GO:0014013 50 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
developmental maturation GO:0021700 193 0.010
amide transport GO:0042886 138 0.010
terminal button organization GO:0072553 3 0.010
cell maturation GO:0048469 127 0.010
regulation of cellular response to stress GO:0080135 159 0.010
leukocyte mediated immunity GO:0002443 174 0.010
norepinephrine transport GO:0015874 2 0.010
organic acid transport GO:0015849 101 0.010
regulation of postsynaptic membrane potential GO:0060078 48 0.010
peptide transport GO:0015833 133 0.010
positive regulation of organelle organization GO:0010638 128 0.010

Pak7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.049
nervous system disease DOID:863 0 0.049
disease of anatomical entity DOID:7 0 0.049
eye and adnexa disease DOID:1492 0 0.049
eye disease DOID:5614 0 0.031
organ system cancer DOID:0050686 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.025
retinal degeneration DOID:8466 0 0.024
retinal disease DOID:5679 0 0.024