Mus musculus

40 known processes

Parp2

poly (ADP-ribose) polymerase family, member 2

(Aliases: PARP-2,Aspartl2,Adprtl2,Adprt2,C78626)

Parp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 107 0.610
dna metabolic process GO:0006259 303 0.235
mrna processing GO:0006397 63 0.231
rna processing GO:0006396 105 0.227
nucleic acid transport GO:0050657 18 0.200
rna 3 end processing GO:0031123 20 0.170
mitotic chromosome condensation GO:0007076 1 0.166
dna replication GO:0006260 52 0.140
mrna 3 end processing GO:0031124 16 0.132
double strand break repair via nonhomologous end joining GO:0006303 10 0.114
non recombinational repair GO:0000726 10 0.102
mrna transport GO:0051028 13 0.097
organic cyclic compound catabolic process GO:1901361 295 0.095
rna localization GO:0006403 23 0.081
nuclear division GO:0000280 158 0.075
regulation of cell cycle process GO:0010564 160 0.072
dna replication checkpoint GO:0000076 2 0.070
meiotic cell cycle GO:0051321 122 0.069
rna transport GO:0050658 18 0.065
translesion synthesis GO:0019985 1 0.064
mrna metabolic process GO:0016071 84 0.064
production of molecular mediator of immune response GO:0002440 103 0.062
organelle fission GO:0048285 170 0.059
intra s dna damage checkpoint GO:0031573 4 0.059
somatic diversification of immune receptors GO:0002200 53 0.059
nitrogen compound transport GO:0071705 271 0.058
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.058
mismatch repair GO:0006298 8 0.057
ncrna processing GO:0034470 26 0.057
establishment of rna localization GO:0051236 18 0.056
somatic cell dna recombination GO:0016444 51 0.056
dna conformation change GO:0071103 37 0.055
microtubule based process GO:0007017 236 0.053
regulation of mrna stability GO:0043488 23 0.051
mitotic cell cycle process GO:1903047 159 0.050
cellular nitrogen compound catabolic process GO:0044270 280 0.050
mrna splicing via spliceosome GO:0000398 43 0.050
nucleobase containing compound transport GO:0015931 27 0.050
somatic diversification of immunoglobulins GO:0016445 43 0.046
cellular amino acid metabolic process GO:0006520 103 0.046
telomere capping GO:0016233 4 0.046
body morphogenesis GO:0010171 45 0.044
peptidyl amino acid modification GO:0018193 336 0.041
mitotic cell cycle GO:0000278 195 0.041
nuclear export GO:0051168 34 0.040
spermatogenesis GO:0007283 284 0.039
posttranscriptional regulation of gene expression GO:0010608 155 0.036
base excision repair GO:0006284 9 0.035
interspecies interaction between organisms GO:0044419 83 0.034
meiotic nuclear division GO:0007126 115 0.034
cellular ketone metabolic process GO:0042180 84 0.033
gene silencing GO:0016458 38 0.031
dna catabolic process GO:0006308 19 0.031
negative regulation of dna replication GO:0008156 4 0.030
regulation of cell cycle phase transition GO:1901987 77 0.029
regulation of cell cycle GO:0051726 281 0.029
positive regulation of cell death GO:0010942 224 0.028
cellular response to dna damage stimulus GO:0006974 207 0.028
germ cell development GO:0007281 185 0.027
internal protein amino acid acetylation GO:0006475 42 0.027
cell cycle checkpoint GO:0000075 47 0.027
inner cell mass cell proliferation GO:0001833 15 0.026
regulation of organelle organization GO:0033043 289 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.025
aromatic compound catabolic process GO:0019439 286 0.025
dna recombination GO:0006310 92 0.025
rna splicing GO:0008380 54 0.025
rna splicing via transesterification reactions GO:0000375 43 0.025
cytoplasmic transport GO:0016482 234 0.025
regulation of antimicrobial humoral response GO:0002759 3 0.024
peripheral nervous system neuron axonogenesis GO:0048936 3 0.023
ncrna 3 end processing GO:0043628 2 0.023
mitotic nuclear division GO:0007067 48 0.023
regulation of interleukin 1 alpha production GO:0032650 4 0.022
telomere maintenance GO:0000723 19 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
regulation of cellular ketone metabolic process GO:0010565 66 0.022
antimicrobial peptide production GO:0002775 2 0.021
regulation of mrna splicing via spliceosome GO:0048024 32 0.020
adult locomotory behavior GO:0008344 91 0.020
meiosis i GO:0007127 60 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.020
compound eye development GO:0048749 1 0.020
regulation of rna stability GO:0043487 26 0.020
lymphocyte differentiation GO:0030098 242 0.019
protein maturation GO:0051604 176 0.019
regulation of mrna metabolic process GO:1903311 43 0.019
heterocycle catabolic process GO:0046700 280 0.019
male gamete generation GO:0048232 285 0.019
meiotic cell cycle process GO:1903046 77 0.019
protein autoprocessing GO:0016540 2 0.019
peptidyl serine modification GO:0018209 83 0.019
gonad development GO:0008406 141 0.019
nuclear transport GO:0051169 139 0.019
regulation of cell cycle g2 m phase transition GO:1902749 10 0.018
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.018
chromatin organization GO:0006325 206 0.018
synapsis GO:0007129 34 0.017
mrna polyadenylation GO:0006378 5 0.017
skin development GO:0043588 220 0.017
dna catabolic process endonucleolytic GO:0000737 15 0.017
regulation of rna splicing GO:0043484 37 0.017
regulation of cellular response to stress GO:0080135 159 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
response to lipopolysaccharide GO:0032496 128 0.016
maturation of 5 8s rrna GO:0000460 1 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
double strand break repair GO:0006302 48 0.016
Mouse
dna integrity checkpoint GO:0031570 28 0.016
methylation GO:0032259 134 0.016
immunoglobulin production GO:0002377 73 0.016
b cell activation GO:0042113 161 0.016
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.015
segmentation GO:0035282 93 0.015
regulation of multi organism process GO:0043900 111 0.015
neural retina development GO:0003407 41 0.015
dna dependent dna replication GO:0006261 24 0.015
gene silencing by rna GO:0031047 19 0.015
mrna export from nucleus GO:0006406 11 0.015
regulation of nuclear division GO:0051783 56 0.015
regulation of dna damage checkpoint GO:2000001 3 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.014
lipoprotein metabolic process GO:0042157 43 0.014
positive regulation of protein modification process GO:0031401 299 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
cellular protein complex assembly GO:0043623 116 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
response to radiation GO:0009314 165 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
nucleotide excision repair GO:0006289 13 0.014
immune effector process GO:0002252 321 0.014
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.014
dendrite development GO:0016358 115 0.013
antimicrobial peptide biosynthetic process GO:0002777 2 0.013
nuclear import GO:0051170 95 0.013
negative regulation of cell cycle process GO:0010948 69 0.013
apoptotic signaling pathway GO:0097190 306 0.013
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
anatomical structure homeostasis GO:0060249 145 0.013
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.013
macromolecule catabolic process GO:0009057 281 0.013
rna phosphodiester bond hydrolysis GO:0090501 19 0.013
positive regulation of programmed cell death GO:0043068 218 0.012
chromosome organization involved in meiosis GO:0070192 39 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
leukocyte differentiation GO:0002521 342 0.012
negative regulation of mrna processing GO:0050686 12 0.012
protein processing GO:0016485 163 0.012
histone mrna metabolic process GO:0008334 3 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
cation transmembrane transport GO:0098655 266 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
atp metabolic process GO:0046034 75 0.012
rhythmic process GO:0048511 174 0.012
amine metabolic process GO:0009308 45 0.012
regulation of cell activation GO:0050865 289 0.012
protein acylation GO:0043543 64 0.012
protein autophosphorylation GO:0046777 61 0.011
mitotic g1 dna damage checkpoint GO:0031571 4 0.011
covalent chromatin modification GO:0016569 163 0.011
peptidyl lysine modification GO:0018205 77 0.011
centrosome organization GO:0051297 26 0.011
multi multicellular organism process GO:0044706 109 0.011
atp catabolic process GO:0006200 55 0.011
regulation of membrane potential GO:0042391 192 0.011
3 utr mediated mrna stabilization GO:0070935 2 0.011
response to organic cyclic compound GO:0014070 198 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
digestive system development GO:0055123 200 0.011
blastocyst development GO:0001824 80 0.011
viral life cycle GO:0019058 36 0.011
positive regulation of immune effector process GO:0002699 107 0.011
posttranscriptional gene silencing by rna GO:0035194 10 0.011
humoral immune response GO:0006959 57 0.011
positive regulation of gene silencing by mirna GO:2000637 1 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
positive regulation of nervous system development GO:0051962 221 0.010
development of primary sexual characteristics GO:0045137 143 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
viral process GO:0016032 41 0.010
respiratory system development GO:0060541 190 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
negative regulation of keratinocyte differentiation GO:0045617 4 0.010
positive regulation of defense response to bacterium GO:1900426 1 0.010

Parp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.020