Mus musculus

54 known processes

Pask

PAS domain containing serine/threonine kinase

(Aliases: mKIAA0135)

Pask biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.511
cellular response to dna damage stimulus GO:0006974 207 0.349
dna repair GO:0006281 107 0.318
meiotic cell cycle GO:0051321 122 0.219
meiotic nuclear division GO:0007126 115 0.210
organelle fission GO:0048285 170 0.205
meiotic cell cycle process GO:1903046 77 0.188
dna recombination GO:0006310 92 0.147
regulation of organelle organization GO:0033043 289 0.146
nuclear division GO:0000280 158 0.144
male meiosis GO:0007140 37 0.144
regulation of cell cycle process GO:0010564 160 0.127
mitotic cell cycle process GO:1903047 159 0.125
mitotic cell cycle GO:0000278 195 0.124
double strand break repair GO:0006302 48 0.105
regulation of mitotic cell cycle phase transition GO:1901990 73 0.101
cellular macromolecule catabolic process GO:0044265 206 0.094
macromolecule catabolic process GO:0009057 281 0.089
spermatogenesis GO:0007283 284 0.086
regulation of cellular amine metabolic process GO:0033238 20 0.074
dna endoreduplication GO:0042023 4 0.074
regulation of proteolysis GO:0030162 164 0.073
meiosis i GO:0007127 60 0.069
regulation of mitotic cell cycle GO:0007346 126 0.064
negative regulation of mitotic cell cycle GO:0045930 58 0.062
regulation of cell cycle GO:0051726 281 0.062
heterocycle catabolic process GO:0046700 280 0.062
male gamete generation GO:0048232 285 0.062
negative regulation of cell cycle phase transition GO:1901988 48 0.060
protein catabolic process GO:0030163 221 0.058
microtubule based process GO:0007017 236 0.055
dna replication GO:0006260 52 0.054
negative regulation of cell proliferation GO:0008285 296 0.053
microtubule cytoskeleton organization GO:0000226 157 0.051
cellular amine metabolic process GO:0044106 44 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
cell cycle checkpoint GO:0000075 47 0.044
cellular amino acid metabolic process GO:0006520 103 0.044
dna biosynthetic process GO:0071897 22 0.043
endomembrane system organization GO:0010256 147 0.042
protein processing GO:0016485 163 0.041
g1 s transition of mitotic cell cycle GO:0000082 57 0.041
negative regulation of cellular component organization GO:0051129 194 0.041
cellular protein catabolic process GO:0044257 155 0.041
modification dependent protein catabolic process GO:0019941 133 0.040
germ cell development GO:0007281 185 0.039
cell cycle g1 s phase transition GO:0044843 57 0.038
chromatin organization GO:0006325 206 0.038
apoptotic signaling pathway GO:0097190 306 0.037
mitotic cell cycle checkpoint GO:0007093 31 0.036
regulation of cell cycle g2 m phase transition GO:1902749 10 0.035
response to cell cycle checkpoint signaling GO:0072396 1 0.035
gene silencing GO:0016458 38 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.034
regulation of cellular response to stress GO:0080135 159 0.034
dna damage checkpoint GO:0000077 26 0.034
dna integrity checkpoint GO:0031570 28 0.034
membrane organization GO:0061024 245 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
negative regulation of organelle organization GO:0010639 90 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.033
amine metabolic process GO:0009308 45 0.032
spermatid development GO:0007286 108 0.032
cell division GO:0051301 120 0.031
inorganic ion transmembrane transport GO:0098660 234 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
regulation of cell cycle phase transition GO:1901987 77 0.030
protein modification by small protein conjugation GO:0032446 187 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
organic cyclic compound catabolic process GO:1901361 295 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
chromosome segregation GO:0007059 48 0.028
protein maturation GO:0051604 176 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.027
organophosphate catabolic process GO:0046434 232 0.027
negative regulation of molecular function GO:0044092 258 0.027
negative regulation of cell cycle GO:0045786 123 0.026
homeostasis of number of cells GO:0048872 210 0.026
positive regulation of mitotic cell cycle GO:0045931 41 0.026
inorganic cation transmembrane transport GO:0098662 207 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.025
regulation of transferase activity GO:0051338 263 0.024
regulation of protein catabolic process GO:0042176 108 0.024
aromatic compound catabolic process GO:0019439 286 0.024
reactive oxygen species metabolic process GO:0072593 84 0.024
organelle assembly GO:0070925 177 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
cellular protein complex assembly GO:0043623 116 0.023
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.023
cellular ketone metabolic process GO:0042180 84 0.023
negative regulation of cell cycle process GO:0010948 69 0.023
metaphase plate congression GO:0051310 2 0.023
positive regulation of cell cycle phase transition GO:1901989 17 0.023
cellular component assembly involved in morphogenesis GO:0010927 139 0.023
cilium morphogenesis GO:0060271 102 0.023
oxidation reduction process GO:0055114 342 0.022
Human
calcium ion transport GO:0006816 159 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.022
positive regulation of cell death GO:0010942 224 0.022
locomotory behavior GO:0007626 195 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
positive regulation of transferase activity GO:0051347 167 0.021
cellularization GO:0007349 1 0.021
transmembrane transport GO:0055085 412 0.020
g2 m transition of mitotic cell cycle GO:0000086 20 0.020
mapk cascade GO:0000165 281 0.020
regulation of cellular component size GO:0032535 121 0.020
positive regulation of organelle organization GO:0010638 128 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
reciprocal meiotic recombination GO:0007131 16 0.020
heterochromatin organization GO:0070828 4 0.020
regulation of cell cycle g1 s phase transition GO:1902806 35 0.019
regulation of chromosome organization GO:0033044 83 0.019
rho protein signal transduction GO:0007266 32 0.019
forebrain development GO:0030900 302 0.019
reciprocal dna recombination GO:0035825 16 0.019
response to radiation GO:0009314 165 0.019
response to organonitrogen compound GO:0010243 246 0.019
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.019
oogenesis GO:0048477 56 0.018
lateral inhibition GO:0046331 1 0.018
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.018
divalent inorganic cation transport GO:0072511 178 0.018
male meiosis i GO:0007141 16 0.018
lipid biosynthetic process GO:0008610 179 0.018
double strand break repair via homologous recombination GO:0000724 21 0.017
purine containing compound catabolic process GO:0072523 213 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
neuroblast fate commitment GO:0014017 1 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
regulation of cytokine production GO:0001817 266 0.017
sister chromatid segregation GO:0000819 20 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
maintenance of location GO:0051235 89 0.017
protein ubiquitination GO:0016567 171 0.017
regulation of transcription by chromatin organization GO:0034401 0 0.017
ras protein signal transduction GO:0007265 77 0.017
regulation of anatomical structure size GO:0090066 178 0.017
cell fate commitment GO:0045165 210 0.017
asymmetric stem cell division GO:0098722 3 0.017
sister chromatid cohesion GO:0007062 12 0.017
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.016
cellular lipid metabolic process GO:0044255 323 0.016
protein polymerization GO:0051258 57 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
peptidyl amino acid modification GO:0018193 336 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
cation transmembrane transport GO:0098655 266 0.016
attachment of spindle microtubules to kinetochore GO:0008608 4 0.016
negative regulation of protein processing GO:0010955 79 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
regulation of protein kinase activity GO:0045859 232 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
blood vessel morphogenesis GO:0048514 285 0.016
regulation of homeostatic process GO:0032844 182 0.016
leukocyte differentiation GO:0002521 342 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
intracellular protein transport GO:0006886 204 0.015
macromolecule methylation GO:0043414 120 0.015
gland development GO:0048732 330 0.015
purine containing compound metabolic process GO:0072521 311 0.015
divalent metal ion transport GO:0070838 172 0.015
chromatin modification GO:0016568 187 0.015
cation transport GO:0006812 399 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
positive regulation of cell cycle process GO:0090068 61 0.015
angiogenesis GO:0001525 201 0.015
cytokinetic process GO:0032506 2 0.015
mitotic nuclear division GO:0007067 48 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
cytoplasmic transport GO:0016482 234 0.015
organelle localization GO:0051640 179 0.015
negative regulation of protein modification process GO:0031400 163 0.015
t cell activation GO:0042110 289 0.014
anatomical structure homeostasis GO:0060249 145 0.014
actin cytoskeleton organization GO:0030036 220 0.014
establishment of organelle localization GO:0051656 122 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
rna interference GO:0016246 2 0.014
spermatid differentiation GO:0048515 115 0.014
hepaticobiliary system development GO:0061008 67 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
actin filament organization GO:0007015 113 0.014
negative regulation of proteolysis GO:0045861 74 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
synapsis GO:0007129 34 0.014
nuclear dna replication GO:0033260 3 0.014
immune effector process GO:0002252 321 0.014
positive regulation of nervous system development GO:0051962 221 0.014
cell cycle g2 m phase transition GO:0044839 20 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
cell type specific apoptotic process GO:0097285 268 0.014
response to organic cyclic compound GO:0014070 198 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
centrosome separation GO:0051299 4 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
nuclear transport GO:0051169 139 0.013
histone modification GO:0016570 159 0.013
b cell activation GO:0042113 161 0.013
development of primary sexual characteristics GO:0045137 143 0.013
sensory organ morphogenesis GO:0090596 242 0.013
fatty acid metabolic process GO:0006631 121 0.013
chromosome separation GO:0051304 14 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
dna dependent dna replication GO:0006261 24 0.013
response to light stimulus GO:0009416 135 0.013
localization within membrane GO:0051668 4 0.013
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
dephosphorylation GO:0016311 129 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
fertilization GO:0009566 127 0.013
small molecule biosynthetic process GO:0044283 132 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
regulation of mapk cascade GO:0043408 248 0.013
regulation of cell projection organization GO:0031344 206 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.013
regulation of protein processing GO:0070613 96 0.013
stem cell proliferation GO:0072089 117 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of protein localization GO:0032880 231 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
female gamete generation GO:0007292 74 0.012
negative regulation of nuclear division GO:0051784 19 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.012
meiotic chromosome segregation GO:0045132 19 0.012
regulation of neuron differentiation GO:0045664 281 0.012
organic acid biosynthetic process GO:0016053 86 0.012
negative regulation of transferase activity GO:0051348 85 0.012
compound eye development GO:0048749 1 0.012
nucleus organization GO:0006997 45 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
ion transmembrane transport GO:0034220 361 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.012
postreplication repair GO:0006301 5 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
dna catabolic process GO:0006308 19 0.012
stem cell differentiation GO:0048863 268 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
regulation of meiotic cell cycle GO:0051445 34 0.012
negative regulation of immune system process GO:0002683 209 0.012
protein depolymerization GO:0051261 34 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
skeletal system morphogenesis GO:0048705 203 0.012
leukocyte migration GO:0050900 124 0.012
myeloid cell differentiation GO:0030099 233 0.012
histone lysine methylation GO:0034968 50 0.012
lymphocyte differentiation GO:0030098 242 0.012
stem cell development GO:0048864 219 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
mitotic chromosome condensation GO:0007076 1 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
negative regulation of cytoskeleton organization GO:0051494 36 0.011
regulation of hydrolase activity GO:0051336 246 0.011
methylation GO:0032259 134 0.011
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
development of primary female sexual characteristics GO:0046545 73 0.011
regulation of chromatin silencing GO:0031935 2 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
regulation of exit from mitosis GO:0007096 1 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
dna catabolic process endonucleolytic GO:0000737 15 0.011
camera type eye development GO:0043010 266 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
germ line stem cell division GO:0042078 2 0.011
cell adhesion GO:0007155 329 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
myeloid cell homeostasis GO:0002262 114 0.011
regulation of hormone levels GO:0010817 211 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
regulation of mitosis GO:0007088 29 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.011
gonad development GO:0008406 141 0.011
adult locomotory behavior GO:0008344 91 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
striated muscle tissue development GO:0014706 293 0.011
oocyte construction GO:0007308 2 0.011
regulation of asymmetric cell division GO:0009786 4 0.011
somatic diversification of immune receptors GO:0002200 53 0.011
negative regulation of cell development GO:0010721 169 0.011
regulation of g2 m transition of mitotic cell cycle GO:0010389 10 0.011
cell maturation GO:0048469 127 0.011
nucleotide metabolic process GO:0009117 332 0.011
regulation of nuclear division GO:0051783 56 0.011
male genitalia morphogenesis GO:0048808 4 0.011
positive regulation of histone methylation GO:0031062 16 0.011
cellular ion homeostasis GO:0006873 165 0.011
cilium assembly GO:0042384 81 0.011
oocyte differentiation GO:0009994 35 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.010
regulation of membrane potential GO:0042391 192 0.010
regulation of cell division GO:0051302 76 0.010
mitotic cytokinesis GO:0000281 4 0.010
recombinational repair GO:0000725 21 0.010
endocytosis GO:0006897 168 0.010
regulation of chromosome segregation GO:0051983 21 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
intracellular mrna localization GO:0008298 4 0.010
signal transduction by p53 class mediator GO:0072331 51 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
positive regulation of protein modification process GO:0031401 299 0.010
positive regulation of cellular protein catabolic process GO:1903364 34 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
nucleoside metabolic process GO:0009116 246 0.010
positive regulation of proteolysis GO:0045862 85 0.010
synaptic transmission GO:0007268 329 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
exocytosis GO:0006887 121 0.010
erythrocyte differentiation GO:0030218 88 0.010
meiotic dna repair synthesis GO:0000711 4 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
skeletal system development GO:0001501 356 0.010
lymphocyte proliferation GO:0046651 164 0.010
stress activated protein kinase signaling cascade GO:0031098 81 0.010
developmental maturation GO:0021700 193 0.010

Pask disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
congenital hypoplastic anemia DOID:1342 0 0.089
immune system disease DOID:2914 0 0.089
aplastic anemia DOID:12449 0 0.089
disease of anatomical entity DOID:7 0 0.089
bone marrow disease DOID:4961 0 0.089
anemia DOID:2355 0 0.089
hematopoietic system disease DOID:74 0 0.089
disease of cellular proliferation DOID:14566 0 0.042
cancer DOID:162 0 0.042
organ system cancer DOID:0050686 0 0.039
gastrointestinal system cancer DOID:3119 0 0.027
large intestine cancer DOID:5672 0 0.017
intestinal cancer DOID:10155 0 0.017
nervous system disease DOID:863 0 0.013
fanconi s anemia DOID:13636 0 0.011