Mus musculus

120 known processes

Pax1

paired box gene 1

(Aliases: hunchback,undulated,wt,Pax-1,un,MGC175950,hbs)

Pax1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 276 0.995
Mouse
epithelial tube morphogenesis GO:0060562 303 0.979
Mouse
regionalization GO:0003002 337 0.970
blood vessel morphogenesis GO:0048514 285 0.964
skeletal system development GO:0001501 356 0.961
heart morphogenesis GO:0003007 178 0.945
gland development GO:0048732 330 0.933
sensory organ morphogenesis GO:0090596 242 0.919
Mouse
amine metabolic process GO:0009308 45 0.861
Mouse
glial cell differentiation GO:0010001 131 0.860
Mouse
muscle tissue development GO:0060537 308 0.850
Mouse
digestive tract development GO:0048565 190 0.800
Mouse
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.784
endodermal cell fate specification GO:0001714 4 0.781
epithelial cell proliferation GO:0050673 174 0.781
skeletal system morphogenesis GO:0048705 203 0.780
cerebral cortex development GO:0021987 86 0.778
regulation of cell motility GO:2000145 236 0.765
urogenital system development GO:0001655 261 0.759
Mouse
mesenchyme development GO:0060485 152 0.733
camera type eye development GO:0043010 266 0.728
Mouse
astrocyte differentiation GO:0048708 43 0.721
diencephalon development GO:0021536 63 0.719
angiogenesis GO:0001525 201 0.716
mesenchymal cell differentiation GO:0048762 107 0.705
Mouse
forebrain development GO:0030900 302 0.705
cartilage development GO:0051216 140 0.702
cardiac muscle tissue morphogenesis GO:0055008 44 0.695
cardiac chamber morphogenesis GO:0003206 93 0.694
gastrulation GO:0007369 116 0.690
Mouse
morphogenesis of a branching structure GO:0001763 203 0.688
Mouse
stem cell differentiation GO:0048863 268 0.687
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.681
regulation of cellular amino acid metabolic process GO:0006521 5 0.680
Mouse
peptidyl tyrosine modification GO:0018212 145 0.676
paraxial mesodermal cell differentiation GO:0048342 2 0.675
cardiac ventricle morphogenesis GO:0003208 50 0.675
apoptotic process involved in development GO:1902742 28 0.670
Mouse
telencephalon development GO:0021537 186 0.669
hypophysis morphogenesis GO:0048850 3 0.661
regulation of stem cell differentiation GO:2000736 50 0.658
Mouse
embryonic heart tube development GO:0035050 65 0.657
regulation of cellular amine metabolic process GO:0033238 20 0.648
Mouse
muscle system process GO:0003012 141 0.647
ear development GO:0043583 200 0.643
Mouse
blood circulation GO:0008015 195 0.642
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.638
cell fate commitment GO:0045165 210 0.631
Mouse
trachea cartilage morphogenesis GO:0060535 4 0.625
branching morphogenesis of an epithelial tube GO:0048754 159 0.621
Mouse
mesenchymal cell development GO:0014031 93 0.619
muscle tissue morphogenesis GO:0060415 53 0.616
rho protein signal transduction GO:0007266 32 0.616
gliogenesis GO:0042063 141 0.615
Mouse
axis elongation involved in somitogenesis GO:0090245 4 0.611
stem cell development GO:0048864 219 0.609
Mouse
sensory perception of sound GO:0007605 97 0.607
glial cell development GO:0021782 54 0.605
cardiac chamber development GO:0003205 108 0.605
astrocyte fate commitment GO:0060018 4 0.605
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.594
striated muscle tissue development GO:0014706 293 0.592
Mouse
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.586
renal system development GO:0072001 225 0.578
Mouse
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.576
ear morphogenesis GO:0042471 118 0.570
Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.569
muscle cell development GO:0055001 133 0.554
embryonic epithelial tube formation GO:0001838 130 0.548
Mouse
pyramidal neuron migration GO:0021852 1 0.543
outflow tract morphogenesis GO:0003151 53 0.541
pallium development GO:0021543 120 0.529
positive regulation of kinase activity GO:0033674 155 0.528
kidney development GO:0001822 213 0.522
Mouse
positive regulation of cell migration GO:0030335 109 0.522
t cell activation GO:0042110 289 0.522
t cell differentiation GO:0030217 174 0.520
somatotropin secreting cell differentiation GO:0060126 4 0.516
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.513
neural tube development GO:0021915 160 0.504
Mouse
mesonephric tubule development GO:0072164 94 0.502
Mouse
positive regulation of cell development GO:0010720 237 0.499
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.498
tissue homeostasis GO:0001894 115 0.498
lung induction GO:0060492 3 0.497
regulation of kinase activity GO:0043549 249 0.491
cochlea morphogenesis GO:0090103 22 0.484
Mouse
cell fate determination GO:0001709 32 0.476
Mouse
skeletal muscle organ development GO:0060538 163 0.471
Mouse
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.469
cerebral cortex neuron differentiation GO:0021895 19 0.468
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.465
renal vesicle induction GO:0072034 3 0.451
midbrain hindbrain boundary maturation GO:0021732 1 0.448
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.447
digestive system development GO:0055123 200 0.447
Mouse
ureteric bud morphogenesis GO:0060675 62 0.445
Mouse
regulation of transferase activity GO:0051338 263 0.439
muscle cell differentiation GO:0042692 261 0.436
circulatory system process GO:0003013 197 0.434
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.432
Mouse
regulation of cell adhesion GO:0030155 154 0.431
axonogenesis GO:0007409 274 0.430
mesonephric duct formation GO:0072181 2 0.425
positive regulation of protein phosphorylation GO:0001934 242 0.420
central nervous system vasculogenesis GO:0022009 3 0.417
morphogenesis of embryonic epithelium GO:0016331 159 0.411
Mouse
cardiac atrium morphogenesis GO:0003209 23 0.408
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.407
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.406
pancreatic a cell fate commitment GO:0003326 2 0.405
cell adhesion GO:0007155 329 0.402
artery development GO:0060840 53 0.398
mesoderm morphogenesis GO:0048332 64 0.397
Mouse
subpallium neuron fate commitment GO:0060163 2 0.392
multicellular organismal homeostasis GO:0048871 164 0.392
rhythmic process GO:0048511 174 0.388
limbic system development GO:0021761 72 0.387
apoptotic process involved in morphogenesis GO:0060561 25 0.386
Mouse
inner ear morphogenesis GO:0042472 101 0.383
Mouse
regulation of response to wounding GO:1903034 189 0.380
glycoprotein metabolic process GO:0009100 116 0.377
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.376
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.372
aorta morphogenesis GO:0035909 22 0.370
segment specification GO:0007379 15 0.369
lymphocyte differentiation GO:0030098 242 0.368
cell type specific apoptotic process GO:0097285 268 0.363
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.362
regulation of glial cell differentiation GO:0045685 41 0.356
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.351
nephron tubule morphogenesis GO:0072078 68 0.351
Mouse
embryonic eye morphogenesis GO:0048048 29 0.350
Mouse
sensory perception GO:0007600 245 0.350
tissue remodeling GO:0048771 102 0.349
positive regulation of cell motility GO:2000147 116 0.348
anatomical structure homeostasis GO:0060249 145 0.347
developmental maturation GO:0021700 193 0.342
Mouse
cardiac epithelial to mesenchymal transition GO:0060317 18 0.339
actin cytoskeleton organization GO:0030036 220 0.338
positive regulation of protein kinase activity GO:0045860 144 0.337
cardiac atrium development GO:0003230 24 0.337
mesonephric epithelium development GO:0072163 94 0.336
Mouse
mesonephric duct morphogenesis GO:0072180 4 0.336
kidney epithelium development GO:0072073 121 0.325
Mouse
endodermal cell fate commitment GO:0001711 12 0.323
positive regulation of interleukin 8 secretion GO:2000484 1 0.317
regulation of ras protein signal transduction GO:0046578 114 0.317
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.317
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.315
regulation of epithelial cell proliferation GO:0050678 141 0.315
forebrain regionalization GO:0021871 25 0.314
cellular ketone metabolic process GO:0042180 84 0.312
Mouse
regulation of cardioblast differentiation GO:0051890 3 0.311
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.310
Mouse
chemotaxis GO:0006935 247 0.304
neuron migration GO:0001764 122 0.304
somitogenesis GO:0001756 69 0.304
endoderm formation GO:0001706 20 0.303
positive regulation of cell adhesion GO:0045785 80 0.302
neuron projection guidance GO:0097485 141 0.302
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.301
regulation of auditory receptor cell differentiation GO:0045607 4 0.300
skeletal muscle cell differentiation GO:0035914 66 0.299
Mouse
leukocyte migration GO:0050900 124 0.299
oligodendrocyte differentiation GO:0048709 53 0.299
positive regulation of lymphocyte activation GO:0051251 140 0.296
specification of organ identity GO:0010092 30 0.295
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.293
neural crest cell development GO:0014032 48 0.293
regulation of cell migration GO:0030334 219 0.291
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.289
Mouse
embryonic skeletal system development GO:0048706 120 0.288
regulation of cellular response to stress GO:0080135 159 0.288
thymus development GO:0048538 41 0.286
primary prostatic bud elongation GO:0060516 2 0.286
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.286
ovulation cycle GO:0042698 59 0.282
negative regulation of nervous system development GO:0051961 156 0.279
epithelial tube formation GO:0072175 130 0.279
Mouse
positive regulation of nervous system development GO:0051962 221 0.278
Mouse
cellular amine metabolic process GO:0044106 44 0.277
Mouse
metanephric nephron tubule formation GO:0072289 4 0.276
Mouse
cell fate specification GO:0001708 72 0.276
Mouse
negative regulation of cell motility GO:2000146 61 0.276
ameboidal type cell migration GO:0001667 128 0.274
renal inner medulla development GO:0072053 3 0.273
establishment of organ orientation GO:0048561 1 0.268
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.268
cardiocyte differentiation GO:0035051 87 0.268
forebrain neuron differentiation GO:0021879 52 0.264
regulation of organ morphogenesis GO:2000027 144 0.264
Mouse
myeloid cell differentiation GO:0030099 233 0.263
embryonic skeletal system morphogenesis GO:0048704 91 0.261
positive regulation of mapk cascade GO:0043410 170 0.261
neural crest cell differentiation GO:0014033 54 0.260
blood vessel endothelial cell migration GO:0043534 23 0.260
muscle contraction GO:0006936 101 0.259
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.259
central nervous system morphogenesis GO:0021551 2 0.258
head morphogenesis GO:0060323 34 0.251
Mouse
regulation of vasculature development GO:1901342 88 0.250
ribonucleoside triphosphate catabolic process GO:0009203 199 0.249
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.249
tissue regeneration GO:0042246 22 0.248
regulation of cytokine production GO:0001817 266 0.248
cardiac muscle tissue development GO:0048738 130 0.246
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.246
regulation of membrane potential GO:0042391 192 0.246
positive regulation of protein modification process GO:0031401 299 0.246
peripheral nervous system development GO:0007422 53 0.244
regulation of cellular ketone metabolic process GO:0010565 66 0.244
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.242
mesonephros development GO:0001823 97 0.240
Mouse
auditory receptor cell fate specification GO:0042667 1 0.240
epithelial cell morphogenesis GO:0003382 41 0.239
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.239
determination of left right symmetry GO:0007368 80 0.238
spinal cord development GO:0021510 81 0.238
nucleoside metabolic process GO:0009116 246 0.237
determination of heart left right asymmetry GO:0061371 48 0.236
regulation of homeostatic process GO:0032844 182 0.235
endoderm development GO:0007492 45 0.234
Mouse
negative regulation of cell fate specification GO:0009996 4 0.233
ossification GO:0001503 216 0.231
spemann organizer formation GO:0060061 2 0.230
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.229
central nervous system neuron differentiation GO:0021953 162 0.229
lung development GO:0030324 164 0.227
telencephalon regionalization GO:0021978 14 0.226
regulation of striated muscle cell differentiation GO:0051153 81 0.225
cell differentiation involved in embryonic placenta development GO:0060706 26 0.225
regulation of neuron differentiation GO:0045664 281 0.224
regulation of retina development in camera type eye GO:1902866 3 0.223
regulation of gliogenesis GO:0014013 50 0.222
regulation of lymphocyte activation GO:0051249 240 0.220
myotube differentiation GO:0014902 105 0.219
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.215
negative regulation of cell development GO:0010721 169 0.214
Mouse
neural tube formation GO:0001841 108 0.214
Mouse
forebrain generation of neurons GO:0021872 63 0.211
organic hydroxy compound transport GO:0015850 93 0.211
cation transport GO:0006812 399 0.210
regulation of anagen GO:0051884 1 0.210
negative regulation of cell proliferation GO:0008285 296 0.209
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.208
somite development GO:0061053 81 0.208
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.207
odontogenesis GO:0042476 78 0.207
Mouse
segmentation GO:0035282 93 0.207
sensory perception of mechanical stimulus GO:0050954 107 0.207
regulation of neural precursor cell proliferation GO:2000177 70 0.206
purine containing compound catabolic process GO:0072523 213 0.206
cellular amino acid metabolic process GO:0006520 103 0.206
Mouse
positive regulation of map kinase activity GO:0043406 84 0.204
regulation of cell activation GO:0050865 289 0.202
neural tube closure GO:0001843 90 0.202
Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.201
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.200
inner medullary collecting duct development GO:0072061 2 0.199
pancreatic pp cell differentiation GO:0003312 2 0.199
ventral spinal cord development GO:0021517 48 0.199
mammary gland morphogenesis GO:0060443 54 0.198
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.197
gonad development GO:0008406 141 0.197
olfactory bulb development GO:0021772 30 0.197
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 5 0.197
Mouse
pituitary gland development GO:0021983 38 0.197
negative regulation of gastrulation GO:2000542 3 0.196
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.196
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.196
positive regulation of cell activation GO:0050867 158 0.195
negative regulation of neuron projection development GO:0010977 50 0.194
embryonic placenta development GO:0001892 98 0.194
ribonucleoside metabolic process GO:0009119 245 0.193
negative regulation of neuron differentiation GO:0045665 101 0.192
response to acid chemical GO:0001101 111 0.191
Mouse
regulation of hormone levels GO:0010817 211 0.191
Mouse
digestive tract morphogenesis GO:0048546 147 0.191
Mouse
homeostasis of number of cells GO:0048872 210 0.191
endocrine system development GO:0035270 98 0.190
regulation of myotube differentiation GO:0010830 62 0.190
stem cell maintenance GO:0019827 130 0.190
Mouse
regulation of neuron projection development GO:0010975 169 0.189
regulation of protein kinase activity GO:0045859 232 0.189
small gtpase mediated signal transduction GO:0007264 97 0.184
positive regulation of transcription by glucose GO:0046016 3 0.184
regulation of blood vessel endothelial cell migration GO:0043535 12 0.183
nucleotide catabolic process GO:0009166 217 0.183
somite rostral caudal axis specification GO:0032525 13 0.183
nephron morphogenesis GO:0072028 69 0.182
Mouse
mitral valve development GO:0003174 4 0.182
regulation of hydrolase activity GO:0051336 246 0.181
hormone metabolic process GO:0042445 86 0.180
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.180
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.180
purine nucleoside catabolic process GO:0006152 205 0.180
heart formation GO:0060914 16 0.179
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.179
metanephric loop of henle development GO:0072236 4 0.178
telencephalon cell migration GO:0022029 55 0.178
morphogenesis of a branching epithelium GO:0061138 193 0.177
Mouse
skin development GO:0043588 220 0.177
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.176
negative regulation of mesodermal cell fate specification GO:0042662 3 0.175
production of molecular mediator of immune response GO:0002440 103 0.175
cardiac ventricle development GO:0003231 83 0.174
response to pain GO:0048265 26 0.174
palate development GO:0060021 76 0.172
auditory receptor cell fate determination GO:0042668 3 0.172
mammary gland duct morphogenesis GO:0060603 38 0.169
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.168
lung field specification GO:0060424 3 0.168
epithelial to mesenchymal transition GO:0001837 47 0.167
cerebellum formation GO:0021588 1 0.167
response to organonitrogen compound GO:0010243 246 0.166
odontogenesis of dentin containing tooth GO:0042475 66 0.166
chondrocyte differentiation GO:0002062 72 0.165
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.165
lymphocyte proliferation GO:0046651 164 0.164
glycosyl compound catabolic process GO:1901658 206 0.163
nucleoside catabolic process GO:0009164 206 0.162
connective tissue development GO:0061448 179 0.162
olfactory bulb interneuron differentiation GO:0021889 12 0.161
gtp catabolic process GO:0006184 143 0.160
insulin secretion GO:0030073 89 0.160
regulation of protein transport GO:0051223 163 0.159
metanephric dct cell differentiation GO:0072240 3 0.158
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 35 0.158
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.157
Mouse
inflammatory response GO:0006954 244 0.157
monocarboxylic acid metabolic process GO:0032787 191 0.156
positive regulation of apoptotic process GO:0043065 217 0.155
axon guidance GO:0007411 141 0.154
regulation of cellular catabolic process GO:0031329 242 0.154
regulation of system process GO:0044057 200 0.154
response to inorganic substance GO:0010035 96 0.153
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.153
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.153
wnt signaling pathway GO:0016055 188 0.153
forebrain morphogenesis GO:0048853 17 0.153
detection of stimulus GO:0051606 84 0.152
central nervous system neuron development GO:0021954 67 0.152
organ growth GO:0035265 117 0.151
positive regulation of striated muscle cell differentiation GO:0051155 35 0.148
morphogenesis of an epithelial sheet GO:0002011 27 0.148
regulation of neuron death GO:1901214 134 0.147
response to retinoic acid GO:0032526 56 0.146
Mouse
pharyngeal system development GO:0060037 17 0.146
formation of primary germ layer GO:0001704 77 0.146
Mouse
forebrain cell migration GO:0021885 58 0.146
positive regulation of transcription via serum response element binding GO:0010735 1 0.145
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.145
bone resorption GO:0045453 38 0.145
retinal ganglion cell axon guidance GO:0031290 18 0.144
cochlea development GO:0090102 35 0.143
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.142
Mouse
positive regulation of muscle cell differentiation GO:0051149 39 0.141
regulation of embryonic development GO:0045995 71 0.141
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.141
positive regulation of cell death GO:0010942 224 0.141
appendage morphogenesis GO:0035107 149 0.140
face morphogenesis GO:0060325 29 0.140
Mouse
embryonic heart tube formation GO:0003144 1 0.140
uterus morphogenesis GO:0061038 2 0.139
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.138
cellular response to external stimulus GO:0071496 88 0.138
Mouse
glycosyl compound metabolic process GO:1901657 246 0.138
branching involved in ureteric bud morphogenesis GO:0001658 56 0.138
Mouse
dorsal ventral neural tube patterning GO:0021904 28 0.138
heart trabecula morphogenesis GO:0061384 26 0.137
regulation of mesenchymal cell apoptotic process GO:2001053 14 0.137
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.137
Mouse
mitotic cell cycle GO:0000278 195 0.137
peptidyl amino acid modification GO:0018193 336 0.136
organic acid biosynthetic process GO:0016053 86 0.136
heart induction GO:0003129 2 0.135
regulation of epithelial cell migration GO:0010632 35 0.135
development of primary female sexual characteristics GO:0046545 73 0.135
cell fate commitment involved in pattern specification GO:0060581 14 0.134
adult behavior GO:0030534 135 0.134
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.132
specification of organ position GO:0010159 3 0.131
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.131
mesoderm development GO:0007498 100 0.131
Mouse
epithelial cell fate commitment GO:0072148 13 0.130
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.130
organophosphate catabolic process GO:0046434 232 0.129
regulation of map kinase activity GO:0043405 120 0.129
regulation of cellular component biogenesis GO:0044087 181 0.129
lung cell differentiation GO:0060479 30 0.128
negative regulation of cellular protein metabolic process GO:0032269 247 0.127
Mouse
placenta development GO:0001890 140 0.127
prostate gland morphogenetic growth GO:0060737 4 0.124
cell fate specification involved in pattern specification GO:0060573 11 0.123
vascular process in circulatory system GO:0003018 62 0.123
regulation of apoptotic signaling pathway GO:2001233 197 0.121
cardiac septum morphogenesis GO:0060411 46 0.121
establishment of anatomical structure orientation GO:0048560 1 0.120
somatic stem cell maintenance GO:0035019 47 0.119
Mouse
peristalsis GO:0030432 8 0.119
forebrain anterior posterior pattern specification GO:0021797 5 0.119
regulation of mitotic cell cycle GO:0007346 126 0.118
cytokine production GO:0001816 319 0.118
regulation of purine nucleotide catabolic process GO:0033121 122 0.118
female gonad development GO:0008585 71 0.118
ventricular cardiac muscle tissue development GO:0003229 38 0.118
epithelial cell migration GO:0010631 63 0.117
covalent chromatin modification GO:0016569 163 0.116
Mouse
cellular response to acid chemical GO:0071229 68 0.116
Mouse
endocardial cushion development GO:0003197 26 0.116
primary neural tube formation GO:0014020 95 0.115
Mouse
regulation of heart morphogenesis GO:2000826 22 0.115
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.114
cardiac right atrium morphogenesis GO:0003213 3 0.114
bone mineralization GO:0030282 54 0.114
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.113
paraxial mesoderm development GO:0048339 18 0.113
purine nucleoside triphosphate metabolic process GO:0009144 226 0.112
adaptive immune response GO:0002250 155 0.112
metanephric collecting duct development GO:0072205 7 0.112
Mouse
single organismal cell cell adhesion GO:0016337 131 0.110
mesoderm formation GO:0001707 62 0.110
Mouse
regulation of bone mineralization GO:0030500 31 0.109
embryonic viscerocranium morphogenesis GO:0048703 8 0.109
bmp signaling pathway GO:0030509 93 0.108
positive regulation of mitotic cell cycle GO:0045931 41 0.108
embryonic camera type eye development GO:0031076 36 0.108
Mouse
positive regulation of jnk cascade GO:0046330 46 0.108
cardiac muscle cell differentiation GO:0055007 69 0.107
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.107
locomotory behavior GO:0007626 195 0.107
regulation of body fluid levels GO:0050878 162 0.107
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.107
establishment of endothelial blood brain barrier GO:0014045 3 0.106
loop of henle development GO:0072070 10 0.106
notch signaling pathway GO:0007219 71 0.104
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.104
regulation of endothelial cell migration GO:0010594 22 0.104
developmental growth involved in morphogenesis GO:0060560 138 0.104
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.104
Mouse
adult locomotory behavior GO:0008344 91 0.103
monoamine transport GO:0015844 33 0.102
positive regulation of leukocyte proliferation GO:0070665 73 0.102
nephron development GO:0072006 109 0.102
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.102
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.102
endodermal cell fate determination GO:0007493 2 0.101
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.101
interleukin 1 beta secretion GO:0050702 16 0.100
striated muscle cell development GO:0055002 125 0.100
positive regulation of transferase activity GO:0051347 167 0.100
extracellular matrix organization GO:0030198 147 0.099
apoptotic signaling pathway GO:0097190 306 0.099
negative regulation of response to wounding GO:1903035 77 0.098
positive regulation of glial cell differentiation GO:0045687 21 0.098
purine nucleoside metabolic process GO:0042278 241 0.098
nitrogen compound transport GO:0071705 271 0.098
negative regulation of astrocyte differentiation GO:0048712 10 0.098
myoblast differentiation GO:0045445 52 0.097
regulation of interleukin 1 beta production GO:0032651 25 0.097
positive regulation of dna templated transcription initiation GO:2000144 5 0.097
negative chemotaxis GO:0050919 14 0.097
negative regulation of prostatic bud formation GO:0060686 4 0.097
ventral spinal cord interneuron fate commitment GO:0060579 14 0.096
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.096
ureter morphogenesis GO:0072197 4 0.096
Mouse
positive regulation of secretion by cell GO:1903532 114 0.096
cell adhesion mediated by integrin GO:0033627 18 0.096
neural tube patterning GO:0021532 43 0.096
regulation of neural retina development GO:0061074 3 0.095
positive regulation of glial cell proliferation GO:0060252 4 0.095
forebrain neuron fate commitment GO:0021877 13 0.095
female sex differentiation GO:0046660 84 0.095
myotube cell development GO:0014904 60 0.095
ventricular cardiac myofibril assembly GO:0055005 3 0.095
lung epithelium development GO:0060428 37 0.094
nucleobase containing small molecule metabolic process GO:0055086 352 0.094
appendage development GO:0048736 166 0.094
regulation of synaptic plasticity GO:0048167 87 0.094
astrocyte development GO:0014002 12 0.093
protein maturation GO:0051604 176 0.093
fibroblast growth factor production GO:0090269 4 0.093
synapse assembly GO:0007416 56 0.093
cation transmembrane transport GO:0098655 266 0.093
glycoprotein biosynthetic process GO:0009101 89 0.092
mesodermal cell differentiation GO:0048333 22 0.092
Mouse
divalent inorganic cation transport GO:0072511 178 0.092
foregut regionalization GO:0060423 3 0.091
cellular response to extracellular stimulus GO:0031668 81 0.091

Pax1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.759
disease of anatomical entity DOID:7 0 0.759
musculoskeletal system disease DOID:17 0 0.759
connective tissue disease DOID:65 0 0.759
bone development disease DOID:0080006 0 0.613
dysostosis DOID:1934 0 0.542