Mus musculus

78 known processes

Pcsk5

proprotein convertase subtilisin/kexin type 5

(Aliases: PC5A,PC5/6A,PC6,SPC6,PC5)

Pcsk5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage morphogenesis GO:0035107 149 0.995
limb development GO:0060173 166 0.986
branching morphogenesis of an epithelial tube GO:0048754 159 0.983
kidney development GO:0001822 213 0.980
regionalization GO:0003002 337 0.974
appendage development GO:0048736 166 0.974
skeletal system development GO:0001501 356 0.960
trachea cartilage morphogenesis GO:0060535 4 0.945
forebrain development GO:0030900 302 0.908
urogenital system development GO:0001655 261 0.879
spleen development GO:0048536 39 0.873
renal system development GO:0072001 225 0.868
embryonic appendage morphogenesis GO:0035113 126 0.863
convergent extension GO:0060026 14 0.841
embryonic skeletal system development GO:0048706 120 0.831
gland development GO:0048732 330 0.827
telencephalon development GO:0021537 186 0.813
cell migration involved in gastrulation GO:0042074 13 0.805
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.795
axis elongation involved in somitogenesis GO:0090245 4 0.792
neural tube development GO:0021915 160 0.774
digestive tract development GO:0048565 190 0.773
cytokine production GO:0001816 319 0.772
regulation of alpha beta t cell differentiation GO:0046637 35 0.768
epithelial tube morphogenesis GO:0060562 303 0.767
gastrulation GO:0007369 116 0.766
myeloid cell differentiation GO:0030099 233 0.756
blood vessel morphogenesis GO:0048514 285 0.756
gonad development GO:0008406 141 0.741
steroid metabolic process GO:0008202 119 0.739
morphogenesis of a branching epithelium GO:0061138 193 0.735
leukocyte proliferation GO:0070661 172 0.735
morphogenesis of an epithelial sheet GO:0002011 27 0.726
lung development GO:0030324 164 0.721
morphogenesis of a branching structure GO:0001763 203 0.707
mesonephric duct morphogenesis GO:0072180 4 0.691
developmental growth involved in morphogenesis GO:0060560 138 0.679
digestive tract morphogenesis GO:0048546 147 0.678
positive regulation of protein kinase activity GO:0045860 144 0.678
bone development GO:0060348 120 0.648
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.647
embryonic limb morphogenesis GO:0030326 126 0.641
embryonic organ morphogenesis GO:0048562 276 0.638
bone morphogenesis GO:0060349 78 0.636
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.635
asymmetric stem cell division GO:0098722 3 0.632
left lung development GO:0060459 4 0.619
development of primary sexual characteristics GO:0045137 143 0.616
salivary gland development GO:0007431 37 0.607
kidney epithelium development GO:0072073 121 0.606
heart morphogenesis GO:0003007 178 0.602
regulation of lymphocyte activation GO:0051249 240 0.596
mesonephros development GO:0001823 97 0.594
axonogenesis GO:0007409 274 0.590
cellular metal ion homeostasis GO:0006875 151 0.582
hindlimb morphogenesis GO:0035137 42 0.580
nephric duct formation GO:0072179 4 0.577
determination of left right symmetry GO:0007368 80 0.565
Mouse
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.562
response to organonitrogen compound GO:0010243 246 0.560
endothelium development GO:0003158 45 0.558
regulation of cell adhesion GO:0030155 154 0.555
chemotaxis GO:0006935 247 0.554
positive regulation of t cell differentiation GO:0045582 52 0.552
uterus development GO:0060065 16 0.544
mapk cascade GO:0000165 281 0.542
regulation of cell motility GO:2000145 236 0.540
leukocyte differentiation GO:0002521 342 0.532
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.530
endocrine system development GO:0035270 98 0.528
nephron tubule morphogenesis GO:0072078 68 0.526
regulation of chondrocyte differentiation GO:0032330 33 0.520
renal vesicle induction GO:0072034 3 0.516
lymphocyte differentiation GO:0030098 242 0.514
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.510
embryonic epithelial tube formation GO:0001838 130 0.510
calcium ion homeostasis GO:0055074 127 0.507
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.504
ear morphogenesis GO:0042471 118 0.504
negative regulation of prostatic bud formation GO:0060686 4 0.503
skeletal system morphogenesis GO:0048705 203 0.503
muscle system process GO:0003012 141 0.499
sensory perception GO:0007600 245 0.498
paraxial mesodermal cell fate commitment GO:0048343 2 0.496
small gtpase mediated signal transduction GO:0007264 97 0.495
establishment of planar polarity GO:0001736 28 0.490
negative regulation of myeloid cell differentiation GO:0045638 38 0.488
inflammatory response GO:0006954 244 0.487
brain morphogenesis GO:0048854 32 0.486
endoderm development GO:0007492 45 0.480
cell fate specification involved in pattern specification GO:0060573 11 0.476
interleukin 8 secretion GO:0072606 3 0.474
amine metabolic process GO:0009308 45 0.464
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.463
neuron projection guidance GO:0097485 141 0.457
primary neural tube formation GO:0014020 95 0.456
limb morphogenesis GO:0035108 149 0.452
cell adhesion GO:0007155 329 0.448
mesonephric tubule morphogenesis GO:0072171 63 0.447
regulation of cytokine production GO:0001817 266 0.447
inner medullary collecting duct development GO:0072061 2 0.446
respiratory system development GO:0060541 190 0.444
regulation of cellular ketone metabolic process GO:0010565 66 0.438
positive regulation of protein phosphorylation GO:0001934 242 0.431
morphogenesis of embryonic epithelium GO:0016331 159 0.426
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.421
mesenchyme development GO:0060485 152 0.419
alpha beta t cell differentiation GO:0046632 69 0.417
positive regulation of kinase activity GO:0033674 155 0.415
mesonephric tubule development GO:0072164 94 0.414
regulation of non canonical wnt signaling pathway GO:2000050 12 0.408
somatic stem cell division GO:0048103 19 0.401
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.400
spinal cord development GO:0021510 81 0.399
t cell activation GO:0042110 289 0.398
regulation of angiogenesis GO:0045765 81 0.396
regulation of fat cell differentiation GO:0045598 81 0.395
paraxial mesodermal cell differentiation GO:0048342 2 0.394
cellular chemical homeostasis GO:0055082 215 0.394
positive regulation of cell cell adhesion mediated by cadherin GO:2000049 2 0.393
positive regulation of cartilage development GO:0061036 18 0.392
chondrocyte differentiation GO:0002062 72 0.391
regulation of fibroblast growth factor production GO:0090270 4 0.390
camera type eye development GO:0043010 266 0.390
mesonephric duct formation GO:0072181 2 0.389
regulation of kinase activity GO:0043549 249 0.383
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.380
regulation of testosterone biosynthetic process GO:2000224 2 0.377
determination of heart left right asymmetry GO:0061371 48 0.375
respiratory tube development GO:0030323 167 0.374
t cell differentiation GO:0030217 174 0.374
sensory organ morphogenesis GO:0090596 242 0.371
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.371
mammary gland duct morphogenesis GO:0060603 38 0.370
regulation of cardiac muscle tissue development GO:0055024 31 0.369
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.366
cochlea morphogenesis GO:0090103 22 0.365
floor plate morphogenesis GO:0033505 3 0.365
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.363
regulation of cardiac muscle tissue growth GO:0055021 26 0.361
angiogenesis GO:0001525 201 0.360
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.360
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.360
positive regulation of leukocyte differentiation GO:1902107 86 0.358
male sex differentiation GO:0046661 109 0.358
muscle tissue morphogenesis GO:0060415 53 0.356
single organism cell adhesion GO:0098602 156 0.355
positive regulation of protein modification process GO:0031401 299 0.355
response to fibroblast growth factor GO:0071774 47 0.354
axon guidance GO:0007411 141 0.354
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.352
forelimb morphogenesis GO:0035136 40 0.350
mammary gland epithelium development GO:0061180 65 0.348
cardiocyte differentiation GO:0035051 87 0.348
central nervous system morphogenesis GO:0021551 2 0.339
maintenance of cell number GO:0098727 3 0.339
negative regulation of immune system process GO:0002683 209 0.332
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.332
metal ion homeostasis GO:0055065 189 0.331
negative regulation of cell motility GO:2000146 61 0.327
lung induction GO:0060492 3 0.326
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.322
cellular response to growth factor stimulus GO:0071363 197 0.322
muscle cell differentiation GO:0042692 261 0.321
male gamete generation GO:0048232 285 0.317
Mouse
cellular response to parathyroid hormone stimulus GO:0071374 2 0.310
atrial cardiac muscle tissue development GO:0003228 5 0.309
positive regulation of lymphocyte activation GO:0051251 140 0.308
alcohol metabolic process GO:0006066 116 0.308
cell growth GO:0016049 130 0.307
endothelial cell differentiation GO:0045446 41 0.301
regulation of leukocyte differentiation GO:1902105 159 0.300
midbrain hindbrain boundary maturation GO:0021732 1 0.300
canonical wnt signaling pathway GO:0060070 130 0.300
left lung morphogenesis GO:0060460 3 0.299
regulation of establishment of planar polarity GO:0090175 28 0.299
bronchiole development GO:0060435 3 0.298
cation homeostasis GO:0055080 212 0.297
spemann organizer formation GO:0060061 2 0.297
cardiac muscle tissue development GO:0048738 130 0.295
regulation of mapk cascade GO:0043408 248 0.295
divalent inorganic cation homeostasis GO:0072507 138 0.294
regulation of canonical wnt signaling pathway GO:0060828 82 0.292
cellular response to lipid GO:0071396 145 0.292
response to organic cyclic compound GO:0014070 198 0.292
ureteric bud development GO:0001657 94 0.291
positive regulation of lymphocyte differentiation GO:0045621 61 0.291
hypophysis morphogenesis GO:0048850 3 0.290
forebrain neuron development GO:0021884 30 0.290
neuron projection extension GO:1990138 64 0.289
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.288
regulation of leukocyte proliferation GO:0070663 121 0.287
palate development GO:0060021 76 0.286
regulation of tube size GO:0035150 57 0.285
t cell proliferation GO:0042098 120 0.284
positive regulation of transferase activity GO:0051347 167 0.283
cartilage development GO:0051216 140 0.282
epithelial cell proliferation GO:0050673 174 0.281
renal tubule morphogenesis GO:0061333 72 0.279
diencephalon development GO:0021536 63 0.279
cellular ketone metabolic process GO:0042180 84 0.278
positive regulation of nervous system development GO:0051962 221 0.278
regulation of neurotransmitter levels GO:0001505 87 0.277
regulation of cartilage development GO:0061035 44 0.273
response to acid chemical GO:0001101 111 0.270
cardiac muscle cell differentiation GO:0055007 69 0.269
regulation of inflammatory response GO:0050727 147 0.269
fat cell differentiation GO:0045444 160 0.269
lung morphogenesis GO:0060425 50 0.268
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.267
formation of primary germ layer GO:0001704 77 0.267
establishment of organ orientation GO:0048561 1 0.267
organonitrogen compound catabolic process GO:1901565 264 0.265
positive regulation of chondrocyte differentiation GO:0032332 13 0.265
regulation of heart growth GO:0060420 31 0.265
regulation of transferase activity GO:0051338 263 0.263
embryonic skeletal system morphogenesis GO:0048704 91 0.262
cardiac muscle cell development GO:0055013 39 0.262
muscular septum morphogenesis GO:0003150 4 0.261
cervix development GO:0060067 2 0.261
cell cell signaling involved in mammary gland development GO:0060764 2 0.259
positive regulation of interleukin 8 secretion GO:2000484 1 0.259
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.255
actin filament bundle assembly GO:0051017 40 0.253
mesonephric epithelium development GO:0072163 94 0.249
regulation of cellular amino acid metabolic process GO:0006521 5 0.247
branching involved in salivary gland morphogenesis GO:0060445 26 0.246
positive regulation of cell migration GO:0030335 109 0.245
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.238
testosterone biosynthetic process GO:0061370 2 0.237
regulation of morphogenesis of a branching structure GO:0060688 53 0.236
striated muscle tissue development GO:0014706 293 0.234
regulation of organ morphogenesis GO:2000027 144 0.234
metanephric loop of henle development GO:0072236 4 0.233
nucleotide metabolic process GO:0009117 332 0.232
cellular divalent inorganic cation homeostasis GO:0072503 127 0.232
positive regulation of cell death GO:0010942 224 0.230
hematopoietic progenitor cell differentiation GO:0002244 143 0.229
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.229
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.229
limbic system development GO:0021761 72 0.226
cardiac septum morphogenesis GO:0060411 46 0.225
secondary metabolic process GO:0019748 18 0.223
non canonical wnt signaling pathway GO:0035567 33 0.221
kidney rudiment formation GO:0072003 3 0.221
oxygen homeostasis GO:0032364 2 0.221
leukocyte migration GO:0050900 124 0.220
branching involved in ureteric bud morphogenesis GO:0001658 56 0.219
organic hydroxy compound biosynthetic process GO:1901617 77 0.219
regulation of secretion by cell GO:1903530 249 0.218
positive regulation of mapk cascade GO:0043410 170 0.218
ear development GO:0043583 200 0.217
cell substrate adhesion GO:0031589 130 0.216
anagen GO:0042640 13 0.215
regulation of cellular amine metabolic process GO:0033238 20 0.215
nephron epithelium morphogenesis GO:0072088 68 0.215
ras protein signal transduction GO:0007265 77 0.214
regulation of anagen GO:0051884 1 0.214
somitogenesis GO:0001756 69 0.212
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.212
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.211
regulation of purine nucleotide metabolic process GO:1900542 169 0.211
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.211
endodermal cell fate specification GO:0001714 4 0.208
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.206
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.206
central nervous system neuron differentiation GO:0021953 162 0.206
cellular calcium ion homeostasis GO:0006874 119 0.205
regulation of protein serine threonine kinase activity GO:0071900 157 0.204
regulation of wnt signaling pathway GO:0030111 123 0.204
positive regulation of heart growth GO:0060421 18 0.203
cardiac muscle tissue growth GO:0055017 37 0.203
regulation of ras protein signal transduction GO:0046578 114 0.203
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.201
head morphogenesis GO:0060323 34 0.198
regulation of epithelial cell proliferation GO:0050678 141 0.197
prostate gland morphogenesis GO:0060512 32 0.196
positive regulation of cellular amine metabolic process GO:0033240 5 0.195
lipid biosynthetic process GO:0008610 179 0.194
positive regulation of cell development GO:0010720 237 0.194
mesoderm formation GO:0001707 62 0.192
spinal cord association neuron differentiation GO:0021527 14 0.192
inner ear morphogenesis GO:0042472 101 0.192
tube closure GO:0060606 91 0.191
digestive system development GO:0055123 200 0.190
positive regulation of programmed cell death GO:0043068 218 0.187
regulation of hormone levels GO:0010817 211 0.186
neural tube closure GO:0001843 90 0.185
purine nucleoside metabolic process GO:0042278 241 0.185
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.184
steroid biosynthetic process GO:0006694 47 0.184
cell proliferation in hindbrain GO:0021534 10 0.184
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.184
regulation of bmp signaling pathway GO:0030510 60 0.183
positive regulation of interleukin 6 production GO:0032755 37 0.183
blood coagulation GO:0007596 76 0.182
cardiac right atrium morphogenesis GO:0003213 3 0.181
small molecule biosynthetic process GO:0044283 132 0.181
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.180
regulation of neuron projection development GO:0010975 169 0.179
cellular amine metabolic process GO:0044106 44 0.178
cellular homeostasis GO:0019725 240 0.176
regulation of t cell differentiation GO:0045580 83 0.176
regulation of ossification GO:0030278 112 0.176
forebrain morphogenesis GO:0048853 17 0.175
organic hydroxy compound metabolic process GO:1901615 203 0.174
cartilage morphogenesis GO:0060536 11 0.174
paramesonephric duct development GO:0061205 3 0.174
regulation of myeloid cell differentiation GO:0045637 96 0.172
regulation of steroid biosynthetic process GO:0050810 26 0.172
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.171
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.170
hindbrain formation GO:0021576 1 0.168
establishment of tissue polarity GO:0007164 28 0.168
multi multicellular organism process GO:0044706 109 0.168
exocrine system development GO:0035272 45 0.168
spinal cord motor neuron cell fate specification GO:0021520 13 0.167
regulation of actin filament bundle assembly GO:0032231 18 0.166
regulation of protein localization GO:0032880 231 0.165
heart growth GO:0060419 45 0.165
regulation of smooth muscle contraction GO:0006940 22 0.164
response to growth factor GO:0070848 198 0.163
heart formation GO:0060914 16 0.163
mesonephric tubule formation GO:0072172 11 0.163
renal inner medulla development GO:0072053 3 0.162
regulation of homeostatic process GO:0032844 182 0.162
epithelial cell development GO:0002064 159 0.162
hindbrain development GO:0030902 128 0.162
regulation of b cell activation GO:0050864 81 0.161
lung associated mesenchyme development GO:0060484 10 0.161
extracellular structure organization GO:0043062 148 0.161
positive regulation of cardiac muscle tissue development GO:0055025 19 0.161
regulation of cell activation GO:0050865 289 0.160
regulation of protein kinase activity GO:0045859 232 0.159
regulation of apoptotic signaling pathway GO:2001233 197 0.158
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.158
cardiac muscle cell proliferation GO:0060038 31 0.157
axis elongation GO:0003401 30 0.157
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.157
positive regulation of fat cell differentiation GO:0045600 32 0.154
stem cell development GO:0048864 219 0.154
locomotory behavior GO:0007626 195 0.154
nephron development GO:0072006 109 0.154
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.153
regulation of t cell activation GO:0050863 170 0.153
positive regulation of ras gtpase activity GO:0032320 65 0.152
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.152
neuron migration GO:0001764 122 0.152
cardiac chamber morphogenesis GO:0003206 93 0.151
purine containing compound metabolic process GO:0072521 311 0.150
midgut development GO:0007494 4 0.150
polarity specification of proximal distal axis GO:0010085 2 0.150
cellular ion homeostasis GO:0006873 165 0.150
negative regulation of bmp signaling pathway GO:0030514 35 0.150
regulation of interleukin 6 production GO:0032675 55 0.149
regulation of cell size GO:0008361 72 0.149
axon extension involved in axon guidance GO:0048846 14 0.149
nucleoside triphosphate metabolic process GO:0009141 230 0.149
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.148
neuronal stem cell division GO:0036445 10 0.148
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.148
male gonad development GO:0008584 88 0.147
labyrinthine layer blood vessel development GO:0060716 21 0.147
actin cytoskeleton organization GO:0030036 220 0.146
primary prostatic bud elongation GO:0060516 2 0.146
regulation of stress activated mapk cascade GO:0032872 69 0.146
regulation of organ growth GO:0046620 61 0.145
ureteric bud morphogenesis GO:0060675 62 0.145
bmp signaling pathway GO:0030509 93 0.143
rho protein signal transduction GO:0007266 32 0.143
wnt signaling pathway involved in kidney development GO:0061289 2 0.143
establishment of anatomical structure orientation GO:0048560 1 0.142
hippocampus development GO:0021766 52 0.142
lymphocyte proliferation GO:0046651 164 0.142
androgen biosynthetic process GO:0006702 4 0.142
protein catabolic process GO:0030163 221 0.141
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.141
cardiac muscle tissue morphogenesis GO:0055008 44 0.141
regulation of establishment of protein localization GO:0070201 181 0.140
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.139
odontogenesis of dentin containing tooth GO:0042475 66 0.139
intracellular protein transport GO:0006886 204 0.139
female gonad development GO:0008585 71 0.138
renal tubule development GO:0061326 87 0.138
positive regulation of neuron projection development GO:0010976 79 0.137
glycosyl compound metabolic process GO:1901657 246 0.137
intestinal epithelial cell maturation GO:0060574 2 0.137
central nervous system projection neuron axonogenesis GO:0021952 21 0.136
wnt signaling pathway GO:0016055 188 0.136
cell division GO:0051301 120 0.136
establishment of endothelial blood brain barrier GO:0014045 3 0.136
regulation of cell growth GO:0001558 91 0.135
fasciculation of sensory neuron axon GO:0097155 3 0.135
g protein coupled receptor signaling pathway GO:0007186 243 0.135
regulation of organelle organization GO:0033043 289 0.134
negative regulation of response to wounding GO:1903035 77 0.133
stem cell division GO:0017145 30 0.132
embryonic heart tube development GO:0035050 65 0.132
skeletal muscle organ development GO:0060538 163 0.132
cation transport GO:0006812 399 0.131
olfactory bulb development GO:0021772 30 0.131
gastrulation with mouth forming second GO:0001702 29 0.131
cellular response to inorganic substance GO:0071241 37 0.131
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.130
positive regulation of protein secretion GO:0050714 52 0.130
cell matrix adhesion GO:0007160 68 0.129
organic cyclic compound catabolic process GO:1901361 295 0.129
embryonic hindlimb morphogenesis GO:0035116 32 0.129
positive regulation of t cell apoptotic process GO:0070234 8 0.128
purine ribonucleoside metabolic process GO:0046128 241 0.128
development of primary female sexual characteristics GO:0046545 73 0.128
regulation of ketone biosynthetic process GO:0010566 2 0.128
development of primary male sexual characteristics GO:0046546 88 0.128
divalent metal ion transport GO:0070838 172 0.127
establishment of protein localization to organelle GO:0072594 118 0.126
positive regulation of cell adhesion GO:0045785 80 0.126
regulation of cell migration GO:0030334 219 0.125
regulation of reproductive process GO:2000241 66 0.124
striated muscle cell proliferation GO:0014855 39 0.124
leukocyte chemotaxis GO:0030595 69 0.124
negative regulation of hormone biosynthetic process GO:0032353 4 0.123
endoderm formation GO:0001706 20 0.123
organic hydroxy compound transport GO:0015850 93 0.123
lateral line system development GO:0048925 1 0.123
segmentation GO:0035282 93 0.122
Mouse
homotypic cell cell adhesion GO:0034109 28 0.122
bone marrow development GO:0048539 3 0.122
regulation of cytokine secretion GO:0050707 61 0.122
macromolecule catabolic process GO:0009057 281 0.122
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.122
stem cell differentiation GO:0048863 268 0.121
cardiac cell development GO:0055006 41 0.121
regulation of muscle system process GO:0090257 80 0.120
positive regulation of organ growth GO:0046622 29 0.120
organ induction GO:0001759 21 0.120
muscle tissue development GO:0060537 308 0.120
metanephros morphogenesis GO:0003338 24 0.120
regulation of purine nucleotide catabolic process GO:0033121 122 0.119
forebrain generation of neurons GO:0021872 63 0.119
regulation of hydrolase activity GO:0051336 246 0.118
wound healing GO:0042060 157 0.117
regulation of lipid metabolic process GO:0019216 118 0.117
specification of organ identity GO:0010092 30 0.117
regulation of neuron differentiation GO:0045664 281 0.116
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.116
central nervous system neuron development GO:0021954 67 0.116
leukocyte activation involved in immune response GO:0002366 126 0.116
positive regulation of b cell proliferation GO:0030890 24 0.116
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.115
regulation of nucleotide metabolic process GO:0006140 169 0.115
gas homeostasis GO:0033483 3 0.115
cardiac septum development GO:0003279 59 0.114
specification of organ position GO:0010159 3 0.114
axial mesodermal cell fate commitment GO:0048322 1 0.114
visceral motor neuron differentiation GO:0021524 3 0.113
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.113
regulation of system process GO:0044057 200 0.112
regulation of muscle tissue development GO:1901861 97 0.111
negative regulation of alcohol biosynthetic process GO:1902931 4 0.111
regulation of chemotaxis GO:0050920 53 0.110
skin morphogenesis GO:0043589 38 0.110
epithelial to mesenchymal transition GO:0001837 47 0.110
oviduct development GO:0060066 3 0.110
positive regulation of behavior GO:0048520 40 0.110
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.109
salivary gland morphogenesis GO:0007435 33 0.108
negative regulation of cell proliferation GO:0008285 296 0.107
molting cycle GO:0042303 90 0.107
mesenchyme morphogenesis GO:0072132 32 0.106
nucleoside metabolic process GO:0009116 246 0.105
prostatic bud formation GO:0060513 10 0.105
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.105
negative regulation of wnt signaling pathway GO:0030178 73 0.104
circulatory system process GO:0003013 197 0.104
positive regulation of b cell activation GO:0050871 49 0.104
mammary gland morphogenesis GO:0060443 54 0.104
pigmentation GO:0043473 71 0.103
regulation of cytoskeleton organization GO:0051493 122 0.103
central nervous system vasculogenesis GO:0022009 3 0.103
negative regulation of reproductive process GO:2000242 31 0.103
uterus morphogenesis GO:0061038 2 0.103
epiboly GO:0090504 8 0.102
purine ribonucleotide catabolic process GO:0009154 208 0.102
cell differentiation in hindbrain GO:0021533 24 0.102
endochondral bone morphogenesis GO:0060350 50 0.102
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.101
ribonucleotide catabolic process GO:0009261 208 0.101
response to parathyroid hormone GO:0071107 3 0.100
motor neuron axon guidance GO:0008045 26 0.100
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.100
positive regulation of protein kinase c signaling GO:0090037 1 0.100
interferon gamma production GO:0032609 67 0.100
regulation of defense response GO:0031347 233 0.099
ribonucleoside metabolic process GO:0009119 245 0.099
regulation of protein transport GO:0051223 163 0.099
b cell activation GO:0042113 161 0.099
regulation of alpha beta t cell activation GO:0046634 53 0.098
regulation of stem cell differentiation GO:2000736 50 0.098
renal outer medulla development GO:0072054 2 0.098
trabecula morphogenesis GO:0061383 40 0.098

Pcsk5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org