|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.969
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.921
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.902
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.900
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.898
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
3 |
0.892
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.888
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.886
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.881
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.880
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.871
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.871
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.865
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.856
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.856
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.847
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.844
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.829
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.822
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.820
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.818
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.816
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.813
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.807
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.795
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.791
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.790
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.786
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.780
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.777
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.771
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.753
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.734
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.733
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.729
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.723
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.717
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.706
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.693
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.691
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.690
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.683
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.678
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.668
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.666
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.666
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.659
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.650
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.647
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.647
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.645
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.644
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.638
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.635
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.633
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.621
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.621
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.619
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.607
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.603
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.598
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.593
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.591
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.591
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.590
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.589
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.587
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.586
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.565
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.560
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.558
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.556
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.522
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.519
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.515
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.509
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.504
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.503
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.501
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.492
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.482
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.474
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.474
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.473
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.472
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.464
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.456
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.453
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.448
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.446
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.446
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.443
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.439
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.437
|
|
|
|
negative regulation of cytokine secretion
|
GO:0050710 |
15 |
0.436
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.435
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.433
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.431
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.411
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.406
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.401
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.400
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.400
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.397
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.389
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.384
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.368
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.364
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.361
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.361
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.358
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.356
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.355
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.349
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.349
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.347
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.344
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.338
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.337
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.335
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.330
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.327
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.323
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.320
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.319
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
7 |
0.315
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.314
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.312
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.312
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.311
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.311
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.311
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.310
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.309
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.304
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.301
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.300
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.296
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.295
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.294
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.292
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.291
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.283
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.279
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.276
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.276
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.275
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.275
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.274
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.267
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.265
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.265
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.261
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.259
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.256
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.256
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.253
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.252
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.252
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.249
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.244
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.244
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.238
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.236
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.235
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.235
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.234
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.233
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.230
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.226
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.222
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.219
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.218
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.218
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.214
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.212
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.212
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.211
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.210
|
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.209
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.209
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.208
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.206
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.204
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.202
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
20 |
0.201
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.200
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.199
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.199
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.198
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.198
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.197
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.197
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.196
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.196
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.195
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
10 |
0.194
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.190
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.189
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.185
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.182
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.181
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.180
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.179
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.179
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.177
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.176
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.176
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.172
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.171
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.171
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.171
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.170
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.168
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.167
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.165
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.164
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.163
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.161
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.161
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.160
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.160
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.159
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.159
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.158
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.158
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.156
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.156
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.156
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.155
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.154
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.154
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.153
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.153
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.152
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.152
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.152
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.152
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.148
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.147
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.145
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.145
|
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.144
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.143
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.143
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.143
|
|
|
|
positive regulation of dendritic cell dendrite assembly
|
GO:2000549 |
1 |
0.142
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.140
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.140
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.139
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.138
|
|
|
|
dendritic cell chemotaxis
|
GO:0002407 |
7 |
0.138
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.137
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.137
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.136
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.135
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.135
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.135
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.133
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.132
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.132
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.131
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.131
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.131
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.129
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.129
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.128
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.128
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.128
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.128
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.127
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.126
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.126
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.126
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.126
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.125
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.125
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.123
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.123
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.123
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.123
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.122
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.120
|
|
|
|
positive regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000563 |
1 |
0.119
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.119
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.118
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.118
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.116
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.115
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.115
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.115
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.114
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.112
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.112
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.112
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.111
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.111
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.110
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.109
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.109
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.109
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.108
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.108
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.107
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.106
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.105
|
|
|
|
t helper 1 cell cytokine production
|
GO:0035744 |
1 |
0.105
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.105
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.103
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.103
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
10 |
0.103
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.102
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.102
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.101
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.101
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.100
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.100
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.099
|
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.099
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.098
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.098
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.098
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.097
|
|
|
|
positive regulation of immunoglobulin production in mucosal tissue
|
GO:2000558 |
1 |
0.097
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.096
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.096
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.096
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.095
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.095
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.094
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.093
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.093
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.092
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.092
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
18 |
0.092
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.092
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.092
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.092
|
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.091
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.091
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.090
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.090
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.089
|
|
|
|
t cell chemotaxis
|
GO:0010818 |
6 |
0.089
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.089
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.089
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.089
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.089
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.089
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.088
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.088
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.088
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.088
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.088
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.088
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
2 |
0.088
|
|
|
|
cellular defense response
|
GO:0006968 |
6 |
0.088
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.087
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.087
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.086
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.086
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.086
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.086
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.085
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.085
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.085
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.085
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.084
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.084
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.083
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.083
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.083
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
10 |
0.082
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.082
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.081
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.081
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.081
|
|
|
|
regulation of natural killer cell chemotaxis
|
GO:2000501 |
1 |
0.080
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.080
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.080
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.080
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.079
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.079
|
|
|
|
gamma delta t cell lineage commitment
|
GO:0002365 |
1 |
0.078
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.078
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.078
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.077
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.077
|
|
|
|
negative regulation of myeloid cell apoptotic process
|
GO:0033033 |
11 |
0.077
|
|
|
|
sa node cell action potential
|
GO:0086015 |
4 |
0.077
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.076
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.075
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.075
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.074
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.074
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.074
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.074
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.074
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.073
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.073
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.073
|
|
|
|
positive regulation of t helper 1 type immune response
|
GO:0002827 |
12 |
0.072
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.072
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.072
|
|
|
|
interleukin 10 production
|
GO:0032613 |
23 |
0.071
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.071
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.071
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.071
|
|
|
|
positive regulation of t helper 2 cell cytokine production
|
GO:2000553 |
3 |
0.071
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.070
|
|
|
|
regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000561 |
2 |
0.070
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.069
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.069
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.069
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.069
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.069
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.068
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.068
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.068
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.068
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.067
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.067
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.067
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.066
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.065
|
|
|
|
acid secretion
|
GO:0046717 |
33 |
0.065
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.065
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.065
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.064
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.064
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.064
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.064
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.064
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.064
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.063
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.063
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.063
|
|
|
|
vasodilation
|
GO:0042311 |
28 |
0.063
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.062
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.062
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.062
|
|
|
|
neurohypophysis development
|
GO:0021985 |
2 |
0.062
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.062
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.062
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.061
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.061
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.060
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.059
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.059
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.059
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.059
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.059
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.059
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.059
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.059
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.058
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.058
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.058
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.058
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.058
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.057
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.057
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.057
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.057
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.057
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.056
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.056
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.056
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.056
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.056
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.056
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.056
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.056
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.056
|
|
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.056
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.055
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.055
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.055
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.055
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.055
|
|
|
|
positive regulation of t helper 1 cell cytokine production
|
GO:2000556 |
1 |
0.055
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.055
|
|
|
|
positive regulation of fever generation by positive regulation of prostaglandin secretion
|
GO:0071812 |
2 |
0.054
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.054
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.054
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.054
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.054
|
|
|
|
osteoclast proliferation
|
GO:0002158 |
4 |
0.053
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.053
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.053
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.053
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.053
|
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.052
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.052
|
|
