Mus musculus

72 known processes

Pde3a

phosphodiesterase 3A, cGMP inhibited

(Aliases: C87899,A930022O17Rik)

Pde3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle cell differentiation GO:0042692 261 0.421
regulation of cellular amine metabolic process GO:0033238 20 0.398
blood vessel morphogenesis GO:0048514 285 0.312
cellular amine metabolic process GO:0044106 44 0.290
regionalization GO:0003002 337 0.260
amine metabolic process GO:0009308 45 0.253
regulation of cellular amino acid metabolic process GO:0006521 5 0.243
stem cell differentiation GO:0048863 268 0.228
asymmetric stem cell division GO:0098722 3 0.222
stem cell development GO:0048864 219 0.218
ras protein signal transduction GO:0007265 77 0.215
nucleobase containing small molecule metabolic process GO:0055086 352 0.210
Human Rat
regulation of neuron differentiation GO:0045664 281 0.202
angiogenesis GO:0001525 201 0.187
cellular amino acid metabolic process GO:0006520 103 0.162
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.160
cognition GO:0050890 149 0.158
cell adhesion GO:0007155 329 0.153
cellular ketone metabolic process GO:0042180 84 0.147
positive regulation of cellular amine metabolic process GO:0033240 5 0.145
carbohydrate derivative biosynthetic process GO:1901137 183 0.144
regulation of cellular ketone metabolic process GO:0010565 66 0.144
cellular response to growth factor stimulus GO:0071363 197 0.142
Human
regulation of cell projection organization GO:0031344 206 0.140
peptidyl amino acid modification GO:0018193 336 0.139
mapk cascade GO:0000165 281 0.135
cardiac muscle tissue development GO:0048738 130 0.135
positive regulation of cell development GO:0010720 237 0.131
positive regulation of protein modification process GO:0031401 299 0.124
small gtpase mediated signal transduction GO:0007264 97 0.122
asymmetric neuroblast division GO:0055059 1 0.120
regulation of cellular catabolic process GO:0031329 242 0.120
regulation of muscle system process GO:0090257 80 0.119
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.118
epithelial tube morphogenesis GO:0060562 303 0.116
regulation of hydrolase activity GO:0051336 246 0.115
forebrain development GO:0030900 302 0.112
leukocyte activation involved in immune response GO:0002366 126 0.112
synaptic transmission GO:0007268 329 0.110
negative regulation of protein metabolic process GO:0051248 282 0.110
generation of precursor metabolites and energy GO:0006091 103 0.109
regulation of reproductive process GO:2000241 66 0.107
developmental growth involved in morphogenesis GO:0060560 138 0.106
sympathetic neuron projection extension GO:0097490 4 0.106
extracellular matrix organization GO:0030198 147 0.105
negative regulation of phosphorylation GO:0042326 166 0.105
cell type specific apoptotic process GO:0097285 268 0.101
regulation of protein kinase activity GO:0045859 232 0.101
negative regulation of protein phosphorylation GO:0001933 126 0.099
negative regulation of nervous system development GO:0051961 156 0.099
morphogenesis of embryonic epithelium GO:0016331 159 0.098
wnt signaling pathway GO:0016055 188 0.095
negative regulation of protein modification process GO:0031400 163 0.094
mitochondrion organization GO:0007005 134 0.094
nucleoside phosphate metabolic process GO:0006753 338 0.092
Human Rat
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.092
macromolecule catabolic process GO:0009057 281 0.089
regulation of system process GO:0044057 200 0.088
positive regulation of neuron projection regeneration GO:0070572 2 0.087
learning or memory GO:0007611 148 0.085
canonical wnt signaling pathway GO:0060070 130 0.083
membrane organization GO:0061024 245 0.083
negative regulation of neuron death GO:1901215 98 0.082
gliogenesis GO:0042063 141 0.082
negative regulation of cellular amine metabolic process GO:0033239 1 0.081
neuron death GO:0070997 154 0.080
regulation of multi organism process GO:0043900 111 0.080
regulation of renin secretion into blood stream GO:1900133 4 0.077
regulation of neuron projection development GO:0010975 169 0.077
regulation of striated muscle cell differentiation GO:0051153 81 0.076
organophosphate catabolic process GO:0046434 232 0.076
Human Rat
establishment or maintenance of cell polarity GO:0007163 86 0.075
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.075
regulation of cellular component biogenesis GO:0044087 181 0.075
lymphocyte activation involved in immune response GO:0002285 93 0.075
negative regulation of neuron apoptotic process GO:0043524 92 0.075
striated muscle tissue development GO:0014706 293 0.075
segmentation GO:0035282 93 0.074
urogenital system development GO:0001655 261 0.074
epithelial tube formation GO:0072175 130 0.074
regulation of anatomical structure size GO:0090066 178 0.073
myeloid cell differentiation GO:0030099 233 0.071
establishment of neuroblast polarity GO:0045200 1 0.071
heterocycle catabolic process GO:0046700 280 0.070
Human Rat
regulation of neuron apoptotic process GO:0043523 122 0.069
purine ribonucleotide catabolic process GO:0009154 208 0.069
Human Rat
regulation of cell migration GO:0030334 219 0.069
response to growth factor GO:0070848 198 0.069
Human
regulation of ion transmembrane transport GO:0034765 119 0.069
regulation of mapk cascade GO:0043408 248 0.069
cell growth GO:0016049 130 0.068
negative regulation of cellular protein metabolic process GO:0032269 247 0.066
negative regulation of cell projection organization GO:0031345 56 0.066
purine nucleotide metabolic process GO:0006163 302 0.065
Human Rat
organonitrogen compound catabolic process GO:1901565 264 0.065
Human Rat
embryonic epithelial tube formation GO:0001838 130 0.064
regulation of circadian rhythm GO:0042752 58 0.064
gland development GO:0048732 330 0.063
muscle tissue development GO:0060537 308 0.062
ribonucleotide metabolic process GO:0009259 291 0.062
Human Rat
ribonucleoside metabolic process GO:0009119 245 0.062
regulation of canonical wnt signaling pathway GO:0060828 82 0.062
negative regulation of endothelial cell migration GO:0010596 4 0.062
neuron apoptotic process GO:0051402 142 0.061
embryonic genitalia morphogenesis GO:0030538 4 0.059
cardiocyte differentiation GO:0035051 87 0.059
purine containing compound metabolic process GO:0072521 311 0.058
Human Rat
regulation of cellular component size GO:0032535 121 0.058
regulation of wnt signaling pathway GO:0030111 123 0.058
tissue migration GO:0090130 68 0.058
protein catabolic process GO:0030163 221 0.058
mesodermal cell migration GO:0008078 4 0.058
blood circulation GO:0008015 195 0.058
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.057
learning GO:0007612 98 0.057
jnk cascade GO:0007254 72 0.057
nucleotide metabolic process GO:0009117 332 0.056
Human Rat
negative regulation of neuron projection development GO:0010977 50 0.056
tube closure GO:0060606 91 0.056
regulation of ion transmembrane transporter activity GO:0032412 54 0.056
regulation of muscle tissue development GO:1901861 97 0.056
cell activation involved in immune response GO:0002263 126 0.056
ossification GO:0001503 216 0.056
organonitrogen compound biosynthetic process GO:1901566 192 0.055
negative regulation of cellular component organization GO:0051129 194 0.055
axonogenesis GO:0007409 274 0.055
regulation of gtp catabolic process GO:0033124 113 0.055
transmembrane transport GO:0055085 412 0.053
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.053
regulation of vesicle mediated transport GO:0060627 139 0.053
neural tube development GO:0021915 160 0.053
regulation of neuron death GO:1901214 134 0.053
ribose phosphate metabolic process GO:0019693 291 0.052
Human Rat
glial cell differentiation GO:0010001 131 0.052
regulation of synaptic plasticity GO:0048167 87 0.052
regulation of cellular response to stress GO:0080135 159 0.052
memory GO:0007613 58 0.052
muscle system process GO:0003012 141 0.051
regulation of nucleoside metabolic process GO:0009118 130 0.051
cardiac muscle cell differentiation GO:0055007 69 0.051
circadian rhythm GO:0007623 114 0.051
regulation of cell cycle GO:0051726 281 0.051
lymphocyte differentiation GO:0030098 242 0.051
regulation of protein serine threonine kinase activity GO:0071900 157 0.051
guanosine containing compound metabolic process GO:1901068 144 0.051
extracellular structure organization GO:0043062 148 0.051
purine ribonucleotide metabolic process GO:0009150 290 0.051
Human Rat
leukocyte differentiation GO:0002521 342 0.050
myotube differentiation GO:0014902 105 0.050
oxidation reduction process GO:0055114 342 0.050
inorganic cation transmembrane transport GO:0098662 207 0.050
mesenchymal cell development GO:0014031 93 0.050
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.050
microtubule cytoskeleton organization GO:0000226 157 0.050
positive regulation of mapk cascade GO:0043410 170 0.050
peptidyl tyrosine modification GO:0018212 145 0.050
cation transmembrane transport GO:0098655 266 0.049
compound eye development GO:0048749 1 0.049
regulation of kinase activity GO:0043549 249 0.049
carbohydrate derivative catabolic process GO:1901136 231 0.049
Human Rat
tissue remodeling GO:0048771 102 0.049
positive regulation of cell projection organization GO:0031346 95 0.049
negative regulation of phosphorus metabolic process GO:0010563 184 0.048
ion transmembrane transport GO:0034220 361 0.048
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.048
organic anion transport GO:0015711 137 0.048
positive regulation of muscle cell differentiation GO:0051149 39 0.048
regulation of transferase activity GO:0051338 263 0.047
purine containing compound catabolic process GO:0072523 213 0.047
Human Rat
negative regulation of neuron differentiation GO:0045665 101 0.047
regulation of purine nucleotide metabolic process GO:1900542 169 0.047
trunk neural crest cell migration GO:0036484 4 0.047
purine ribonucleoside metabolic process GO:0046128 241 0.046
skeletal system development GO:0001501 356 0.046
nuclear transport GO:0051169 139 0.046
branching morphogenesis of an epithelial tube GO:0048754 159 0.046
cytokine production GO:0001816 319 0.046
cellular response to organonitrogen compound GO:0071417 145 0.046
Human Mouse
mesenchyme development GO:0060485 152 0.046
positive regulation of protein phosphorylation GO:0001934 242 0.046
ribonucleoside triphosphate metabolic process GO:0009199 220 0.045
purine nucleoside metabolic process GO:0042278 241 0.045
renal system development GO:0072001 225 0.045
microtubule based process GO:0007017 236 0.045
rho protein signal transduction GO:0007266 32 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.044
fat cell differentiation GO:0045444 160 0.044
regulation of cell motility GO:2000145 236 0.044
kidney development GO:0001822 213 0.044
regulation of cytoskeleton organization GO:0051493 122 0.044
single organism cell adhesion GO:0098602 156 0.044
negative regulation of phosphate metabolic process GO:0045936 184 0.043
b cell activation GO:0042113 161 0.043
regulation of organelle organization GO:0033043 289 0.043
cell fate commitment GO:0045165 210 0.042
regulation of organ morphogenesis GO:2000027 144 0.042
positive regulation of nervous system development GO:0051962 221 0.041
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.041
regulation of protein maturation GO:1903317 96 0.041
dendrite development GO:0016358 115 0.041
tube formation GO:0035148 140 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
Human Rat
nucleoside catabolic process GO:0009164 206 0.041
positive regulation of cell migration GO:0030335 109 0.041
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.040
peptidyl serine phosphorylation GO:0018105 74 0.040
positive regulation of neuron differentiation GO:0045666 141 0.040
purine nucleoside triphosphate catabolic process GO:0009146 203 0.040
semicircular canal fusion GO:0060879 1 0.040
epithelial cell migration GO:0010631 63 0.040
regulation of nucleotide metabolic process GO:0006140 169 0.040
guanosine containing compound catabolic process GO:1901069 144 0.039
heart contraction GO:0060047 93 0.039
apoptotic signaling pathway GO:0097190 306 0.039
cellular homeostasis GO:0019725 240 0.038
response to organonitrogen compound GO:0010243 246 0.038
Human Mouse Rat
epithelial cell development GO:0002064 159 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.038
ear development GO:0043583 200 0.038
positive regulation of transferase activity GO:0051347 167 0.038
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.038
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.037
gtp metabolic process GO:0046039 144 0.037
regulation of blood circulation GO:1903522 93 0.037
sympathetic neuron projection guidance GO:0097491 4 0.037
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.037
immune effector process GO:0002252 321 0.037
positive regulation of cellular catabolic process GO:0031331 148 0.036
neural tube formation GO:0001841 108 0.036
cellular response to hormone stimulus GO:0032870 150 0.036
Mouse
labyrinthine layer development GO:0060711 49 0.036
regulation of nucleotide catabolic process GO:0030811 122 0.036
response to insulin GO:0032868 100 0.036
Mouse
mammary gland epithelium development GO:0061180 65 0.036
regulation of lymphocyte activation GO:0051249 240 0.036
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.035
synapse assembly GO:0007416 56 0.035
stem cell maintenance GO:0019827 130 0.035
negative regulation of wnt signaling pathway GO:0030178 73 0.035
nucleoside metabolic process GO:0009116 246 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.035
leukocyte migration GO:0050900 124 0.035
neuron projection guidance GO:0097485 141 0.035
actin cytoskeleton organization GO:0030036 220 0.035
ureteric bud development GO:0001657 94 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
positive regulation of neuron projection development GO:0010976 79 0.034
glycosyl compound metabolic process GO:1901657 246 0.034
hypothalamus gonadotrophin releasing hormone neuron differentiation GO:0021886 4 0.034
regulation of circadian sleep wake cycle GO:0042749 3 0.034
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.034
regulation of response to wounding GO:1903034 189 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
Human Rat
ribonucleoside catabolic process GO:0042454 206 0.033
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.033
cellular calcium ion homeostasis GO:0006874 119 0.033
calcium ion transmembrane transport GO:0070588 85 0.033
developmental cell growth GO:0048588 84 0.032
associative learning GO:0008306 61 0.032
positive regulation of protein kinase activity GO:0045860 144 0.032
t cell differentiation GO:0030217 174 0.032
ribonucleotide catabolic process GO:0009261 208 0.032
Human Rat
nucleoside triphosphate catabolic process GO:0009143 205 0.032
positive regulation of cell motility GO:2000147 116 0.032
multi multicellular organism process GO:0044706 109 0.032
regulation of ossification GO:0030278 112 0.032
establishment or maintenance of neuroblast polarity GO:0045196 1 0.032
negative regulation of bone trabecula formation GO:1900155 1 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
adaptive immune response GO:0002250 155 0.032
single organismal cell cell adhesion GO:0016337 131 0.032
organelle localization GO:0051640 179 0.032
anatomical structure maturation GO:0071695 49 0.031
lipid biosynthetic process GO:0008610 179 0.031
regulation of purine nucleotide catabolic process GO:0033121 122 0.031
regulation of inflammatory response GO:0050727 147 0.031
negative regulation of multi organism process GO:0043901 68 0.031
peripheral nervous system development GO:0007422 53 0.031
carbohydrate metabolic process GO:0005975 230 0.030
regulation of cytokine production GO:0001817 266 0.030
response to peptide GO:1901652 136 0.030
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
immune response regulating signaling pathway GO:0002764 125 0.030
regulation of protein processing GO:0070613 96 0.030
innate immune response GO:0045087 157 0.030
cell maturation GO:0048469 127 0.030
protein maturation GO:0051604 176 0.030
engulfment of apoptotic cell GO:0043652 3 0.030
regulation of ras gtpase activity GO:0032318 88 0.029
placenta development GO:0001890 140 0.029
morphogenesis of a branching structure GO:0001763 203 0.029
positive regulation of calcium ion transmembrane transporter activity GO:1901021 8 0.029
carbohydrate homeostasis GO:0033500 128 0.029
Mouse
regulation of actin filament based process GO:0032970 99 0.029
regulation of transporter activity GO:0032409 57 0.029
bone development GO:0060348 120 0.029
glycoprotein biosynthetic process GO:0009101 89 0.029
nucleotide catabolic process GO:0009166 217 0.029
Human Rat
heart morphogenesis GO:0003007 178 0.028
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.028
peptidyl tyrosine phosphorylation GO:0018108 143 0.028
inflammatory response GO:0006954 244 0.028
skin development GO:0043588 220 0.028
facioacoustic ganglion development GO:1903375 3 0.028
regulation of calcium ion transmembrane transport GO:1903169 20 0.028
negative regulation of cell development GO:0010721 169 0.028
negative regulation of growth GO:0045926 99 0.028
neuron projection regeneration GO:0031102 14 0.027
regulation of white fat cell proliferation GO:0070350 2 0.027
regulation of organ growth GO:0046620 61 0.027
negative regulation of cytoskeleton organization GO:0051494 36 0.027
regulation of cardiac muscle tissue development GO:0055024 31 0.027
purine nucleoside catabolic process GO:0006152 205 0.027
cellular macromolecule catabolic process GO:0044265 206 0.027
liver development GO:0001889 66 0.027
regulation of heart rate GO:0002027 36 0.027
locomotory behavior GO:0007626 195 0.027
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.027
submandibular salivary gland formation GO:0060661 1 0.027
lung development GO:0030324 164 0.027
regulation of cell adhesion GO:0030155 154 0.027
nucleocytoplasmic transport GO:0006913 139 0.027
telencephalon cell migration GO:0022029 55 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
Human Rat
lipid localization GO:0010876 126 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
cellular metal ion homeostasis GO:0006875 151 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.026
Human Rat
interleukin 13 secretion GO:0072611 2 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.026
ameboidal type cell migration GO:0001667 128 0.026
negative regulation of cell motility GO:2000146 61 0.026
cerebral cortex development GO:0021987 86 0.026
endothelial cell proliferation GO:0001935 27 0.026
actin filament organization GO:0007015 113 0.026
cation homeostasis GO:0055080 212 0.026
circulatory system process GO:0003013 197 0.026
Human
regulation of osteoblast differentiation GO:0045667 67 0.026
transmission of nerve impulse GO:0019226 76 0.026
white fat cell proliferation GO:0070343 2 0.026
positive regulation of muscle tissue development GO:1901863 32 0.026
sulfur compound biosynthetic process GO:0044272 37 0.026
cell substrate adhesion GO:0031589 130 0.026
multicellular organismal signaling GO:0035637 91 0.025
alcohol metabolic process GO:0006066 116 0.025
negative regulation of hydrolase activity GO:0051346 71 0.025
synapse organization GO:0050808 125 0.025
mesenchymal cell differentiation GO:0048762 107 0.025
maintenance of location GO:0051235 89 0.025
cellular response to lipid GO:0071396 145 0.025
appendage development GO:0048736 166 0.025
directional locomotion GO:0033058 3 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
inorganic ion transmembrane transport GO:0098660 234 0.025
cellular protein catabolic process GO:0044257 155 0.025
protein polymerization GO:0051258 57 0.025
negative regulation of molecular function GO:0044092 258 0.025
regulation of protein catabolic process GO:0042176 108 0.025
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.025
cellular carbohydrate metabolic process GO:0044262 119 0.025
positive regulation of reproductive process GO:2000243 19 0.025
central nervous system neuron differentiation GO:0021953 162 0.025
glucose homeostasis GO:0042593 128 0.024
Mouse
rhythmic process GO:0048511 174 0.024
mesenchymal epithelial cell signaling involved in lung development GO:0060496 1 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
astrocyte differentiation GO:0048708 43 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
skeletal muscle cell differentiation GO:0035914 66 0.024
regulation of cation channel activity GO:2001257 22 0.024
telencephalon development GO:0021537 186 0.024
positive regulation of secretion by cell GO:1903532 114 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
energy derivation by oxidation of organic compounds GO:0015980 77 0.024
organ growth GO:0035265 117 0.024
bronchiole morphogenesis GO:0060436 1 0.024
positive regulation of gtpase activity GO:0043547 85 0.023
activation of mapk activity GO:0000187 59 0.023
heart process GO:0003015 94 0.023
positive regulation of apoptotic signaling pathway GO:2001235 95 0.023
respiratory tube development GO:0030323 167 0.023
digestive system development GO:0055123 200 0.023
neuron migration GO:0001764 122 0.023
ventral trunk neural crest cell migration GO:0036486 4 0.023
striated muscle cell development GO:0055002 125 0.023
neuron projection extension GO:1990138 64 0.023
regulation of epithelial cell migration GO:0010632 35 0.023
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.023
respiratory system development GO:0060541 190 0.023
regulation of mitotic cell cycle GO:0007346 126 0.023
positive regulation of response to wounding GO:1903036 66 0.023
positive regulation of nucleoside metabolic process GO:0045979 91 0.023
leukocyte homeostasis GO:0001776 79 0.022
blood vessel endothelial cell migration GO:0043534 23 0.022
endothelial cell migration GO:0043542 44 0.022
neural crest cell migration involved in sympathetic nervous system development GO:1903045 1 0.022
peptidyl serine modification GO:0018209 83 0.022
regulation of membrane potential GO:0042391 192 0.022
b cell activation involved in immune response GO:0002312 50 0.022
response to radiation GO:0009314 165 0.022
regulation of body fluid levels GO:0050878 162 0.022
negative regulation of synapse assembly GO:0051964 3 0.022
oocyte axis specification GO:0007309 2 0.022
regulation of protein kinase b signaling GO:0051896 56 0.022
positive regulation of gtp catabolic process GO:0033126 85 0.022
protein localization to membrane GO:0072657 108 0.022
gtp catabolic process GO:0006184 143 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
oocyte construction GO:0007308 2 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
positive regulation of ion transmembrane transport GO:0034767 24 0.022
positive regulation of nucleotide catabolic process GO:0030813 88 0.022
cytoplasmic transport GO:0016482 234 0.022
intracellular protein transport GO:0006886 204 0.021
lipid transport GO:0006869 98 0.021
positive regulation of organ growth GO:0046622 29 0.021
branch elongation involved in salivary gland morphogenesis GO:0060667 2 0.021
cerebellar granule cell precursor proliferation GO:0021930 10 0.021
activation of immune response GO:0002253 138 0.021
glycoprotein metabolic process GO:0009100 116 0.021
neuromuscular process GO:0050905 99 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
negative regulation of axon extension GO:0030517 19 0.021
receptor mediated endocytosis GO:0006898 51 0.021
smoothened signaling pathway GO:0007224 105 0.021
carbohydrate transport GO:0008643 62 0.021
positive regulation of white fat cell proliferation GO:0070352 1 0.021
aromatic compound catabolic process GO:0019439 286 0.021
Human Rat
organophosphate biosynthetic process GO:0090407 122 0.021
polysaccharide metabolic process GO:0005976 39 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
positive regulation of hydrolase activity GO:0051345 148 0.021
positive regulation of oocyte development GO:0060282 4 0.021
endomembrane system organization GO:0010256 147 0.021
positive regulation of cytokine production GO:0001819 174 0.020
epithelium migration GO:0090132 63 0.020
regulation of angiogenesis GO:0045765 81 0.020
negative regulation of cell growth GO:0030308 44 0.020
mitotic cell cycle GO:0000278 195 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
response to transforming growth factor beta GO:0071559 88 0.020
Human
mammary gland bud formation GO:0060615 2 0.020
muscle contraction GO:0006936 101 0.020
negative regulation of immune system process GO:0002683 209 0.019
male gamete generation GO:0048232 285 0.019
regulation of cell growth GO:0001558 91 0.019
protein localization to nucleus GO:0034504 121 0.019
regulation of cellular response to growth factor stimulus GO:0090287 82 0.019
protein localization to organelle GO:0033365 185 0.019
myeloid leukocyte differentiation GO:0002573 119 0.019
small molecule biosynthetic process GO:0044283 132 0.019
cell cell signaling involved in lung development GO:0060495 1 0.019
forebrain cell migration GO:0021885 58 0.019
positive regulation of secretion GO:0051047 130 0.019
regulation of epithelial cell proliferation GO:0050678 141 0.019
positive regulation of vasoconstriction GO:0045907 4 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.019
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.019
positive regulation of thymocyte migration GO:2000412 2 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
response to decreased oxygen levels GO:0036293 59 0.019
anatomical structure homeostasis GO:0060249 145 0.019
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.019
t cell activation involved in immune response GO:0002286 43 0.019
sensory organ morphogenesis GO:0090596 242 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
developmental maturation GO:0021700 193 0.019
cellular response to peptide hormone stimulus GO:0071375 92 0.019
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.019
skeletal muscle organ development GO:0060538 163 0.019
cellular protein complex assembly GO:0043623 116 0.019
epithelial to mesenchymal transition GO:0001837 47 0.019
regulation of voltage gated calcium channel activity GO:1901385 4 0.018
protein import GO:0017038 101 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
cd4 positive alpha beta t cell activation GO:0035710 45 0.018
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.018
central nervous system neuron development GO:0021954 67 0.018
alpha beta t cell differentiation GO:0046632 69 0.018
regulation of heart growth GO:0060420 31 0.018
long term synaptic potentiation GO:0060291 25 0.018
negative regulation of kinase activity GO:0033673 81 0.018
positive regulation of kinase activity GO:0033674 155 0.018
alpha beta t cell activation GO:0046631 91 0.018
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.018
sequestering of calcium ion GO:0051208 18 0.018
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.018
positive regulation of cell cycle GO:0045787 92 0.018
mammary gland duct morphogenesis GO:0060603 38 0.017
stress activated mapk cascade GO:0051403 80 0.017
negative regulation of organelle organization GO:0010639 90 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
axon guidance GO:0007411 141 0.017

Pde3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.041
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017