Mus musculus

65 known processes

Pde6c

phosphodiesterase 6C, cGMP specific, cone, alpha prime

(Aliases: cpfl1)

Pde6c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to radiation GO:0009314 165 0.199
phototransduction GO:0007602 17 0.189
eye photoreceptor cell development GO:0042462 31 0.141
organic cyclic compound catabolic process GO:1901361 295 0.131
Mouse
heterocycle catabolic process GO:0046700 280 0.114
Mouse
acetylcholine transport GO:0015870 2 0.113
sensory perception of light stimulus GO:0050953 54 0.101
sensory organ morphogenesis GO:0090596 242 0.100
transmembrane transport GO:0055085 412 0.099
cellular amine metabolic process GO:0044106 44 0.090
ion transmembrane transport GO:0034220 361 0.087
detection of light stimulus GO:0009583 25 0.077
ribonucleotide catabolic process GO:0009261 208 0.077
Mouse
rhodopsin mediated signaling pathway GO:0016056 4 0.075
carbohydrate derivative catabolic process GO:1901136 231 0.073
Mouse
detection of stimulus GO:0051606 84 0.070
visual perception GO:0007601 52 0.070
regulation of feeding behavior GO:0060259 3 0.069
amine metabolic process GO:0009308 45 0.069
acetylcholine secretion neurotransmission GO:0014055 2 0.069
calcium ion transport GO:0006816 159 0.067
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.067
regulation of cell projection organization GO:0031344 206 0.067
purine containing compound catabolic process GO:0072523 213 0.066
Mouse
regulation of hydrolase activity GO:0051336 246 0.064
cation transport GO:0006812 399 0.063
regulation of protein kinase activity GO:0045859 232 0.061
Mouse
nitrogen compound transport GO:0071705 271 0.060
cellular nitrogen compound catabolic process GO:0044270 280 0.060
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.059
Mouse
aromatic compound catabolic process GO:0019439 286 0.059
Mouse
protein processing GO:0016485 163 0.058
regulation of ion transport GO:0043269 215 0.057
organophosphate catabolic process GO:0046434 232 0.057
Mouse
sensory perception GO:0007600 245 0.057
camera type eye development GO:0043010 266 0.056
positive regulation of protein modification process GO:0031401 299 0.053
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
ribonucleoside metabolic process GO:0009119 245 0.052
positive regulation of dopamine secretion GO:0033603 2 0.052
regulation of mapk cascade GO:0043408 248 0.052
Mouse
cognition GO:0050890 149 0.052
acetate ester transport GO:1901374 2 0.050
negative regulation of molecular function GO:0044092 258 0.049
protein maturation GO:0051604 176 0.049
photoreceptor cell development GO:0042461 40 0.049
regulation of protein maturation GO:1903317 96 0.046
positive regulation of protein phosphorylation GO:0001934 242 0.046
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.045
Mouse
detection of external stimulus GO:0009581 61 0.045
immune effector process GO:0002252 321 0.045
nucleoside metabolic process GO:0009116 246 0.044
regulation of defense response GO:0031347 233 0.043
Mouse
response to light stimulus GO:0009416 135 0.043
glycosyl compound metabolic process GO:1901657 246 0.042
nucleotide catabolic process GO:0009166 217 0.041
Mouse
regulation of kinase activity GO:0043549 249 0.040
Mouse
regulation of transferase activity GO:0051338 263 0.040
Mouse
negative regulation of endothelial cell migration GO:0010596 4 0.040
nucleoside triphosphate metabolic process GO:0009141 230 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.039
glycosyl compound catabolic process GO:1901658 206 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
sensory perception of mechanical stimulus GO:0050954 107 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
Mouse
cell type specific apoptotic process GO:0097285 268 0.038
regulation of action potential GO:0098900 4 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
cation transmembrane transport GO:0098655 266 0.037
ribonucleotide metabolic process GO:0009259 291 0.036
Mouse
regulation of circadian sleep wake cycle GO:0042749 3 0.036
purine containing compound metabolic process GO:0072521 311 0.036
Mouse
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.036
actin cytoskeleton organization GO:0030036 220 0.036
divalent inorganic cation transport GO:0072511 178 0.036
negative regulation of action potential GO:0045759 1 0.036
nucleoside triphosphate catabolic process GO:0009143 205 0.035
negative regulation of hydrolase activity GO:0051346 71 0.035
negative regulation of defense response GO:0031348 77 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.035
synaptic transmission involved in micturition GO:0060084 3 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.035
Mouse
purine nucleotide metabolic process GO:0006163 302 0.034
Mouse
microtubule based process GO:0007017 236 0.034
peptidyl amino acid modification GO:0018193 336 0.034
multi multicellular organism process GO:0044706 109 0.034
negative regulation of protein metabolic process GO:0051248 282 0.033
regulation of cell migration GO:0030334 219 0.033
detection of abiotic stimulus GO:0009582 60 0.033
norepinephrine transport GO:0015874 2 0.032
retina development in camera type eye GO:0060041 119 0.032
regulation of protein processing GO:0070613 96 0.032
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
regulation of proteolysis GO:0030162 164 0.031
regulation of cell activation GO:0050865 289 0.031
Mouse
cytokine production GO:0001816 319 0.031
response to organonitrogen compound GO:0010243 246 0.031
regulation of cytokine production GO:0001817 266 0.031
regulation of protein localization GO:0032880 231 0.031
purine nucleoside metabolic process GO:0042278 241 0.030
divalent metal ion transport GO:0070838 172 0.030
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
ribonucleoside catabolic process GO:0042454 206 0.030
generation of ovulation cycle rhythm GO:0060112 1 0.029
isoprenoid metabolic process GO:0006720 29 0.029
exocytosis GO:0006887 121 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
Mouse
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.028
positive regulation of catecholamine secretion GO:0033605 2 0.028
regulation of dopamine secretion GO:0014059 9 0.028
organelle assembly GO:0070925 177 0.028
spermatogenesis GO:0007283 284 0.028
regulation of transmembrane transport GO:0034762 128 0.028
lateral geniculate nucleus development GO:0021771 1 0.027
endothelial cell migration GO:0043542 44 0.027
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.027
nucleotide metabolic process GO:0009117 332 0.027
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
response to oxygen levels GO:0070482 62 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
eye photoreceptor cell differentiation GO:0001754 41 0.026
regulation of cell motility GO:2000145 236 0.026
regulation of interleukin 6 production GO:0032675 55 0.026
cellular amino acid metabolic process GO:0006520 103 0.025
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
response to inorganic substance GO:0010035 96 0.025
regulation of organelle organization GO:0033043 289 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.024
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.023
t cell activation GO:0042110 289 0.023
Mouse
gtp metabolic process GO:0046039 144 0.023
positive regulation of synaptic transmission dopaminergic GO:0032226 5 0.023
chemotaxis GO:0006935 247 0.023
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.023
activation of immune response GO:0002253 138 0.023
oxidation reduction process GO:0055114 342 0.023
regulation of neurotransmitter levels GO:0001505 87 0.022
phototransduction visible light GO:0007603 6 0.022
defense response to other organism GO:0098542 197 0.022
response to peptide GO:1901652 136 0.022
negative regulation of response to wounding GO:1903035 77 0.022
macromolecule catabolic process GO:0009057 281 0.022
leukocyte differentiation GO:0002521 342 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
regulation of membrane potential GO:0042391 192 0.021
axonogenesis GO:0007409 274 0.021
leukocyte proliferation GO:0070661 172 0.021
Mouse
skeletal system development GO:0001501 356 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
cellular lipid metabolic process GO:0044255 323 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.020
Mouse
negative regulation of proteolysis GO:0045861 74 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
cellular response to lipid GO:0071396 145 0.020
Mouse
peptidyl serine modification GO:0018209 83 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
endocytosis GO:0006897 168 0.020
regulation of cellular component size GO:0032535 121 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.019
actin filament organization GO:0007015 113 0.019
regulation of neuron apoptotic process GO:0043523 122 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
Mouse
regulation of interleukin 1 beta production GO:0032651 25 0.019
cellular ketone metabolic process GO:0042180 84 0.019
cellular protein complex assembly GO:0043623 116 0.019
sensory perception of sound GO:0007605 97 0.019
positive regulation of cytokine production GO:0001819 174 0.019
interleukin 6 production GO:0032635 58 0.018
actin polymerization or depolymerization GO:0008154 54 0.018
central nervous system projection neuron axonogenesis GO:0021952 21 0.018
cytoplasmic transport GO:0016482 234 0.018
positive regulation of transferase activity GO:0051347 167 0.018
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
mapk cascade GO:0000165 281 0.018
Mouse
learning or memory GO:0007611 148 0.018
cellular macromolecule catabolic process GO:0044265 206 0.017
diterpenoid metabolic process GO:0016101 24 0.017
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.017
b cell activation GO:0042113 161 0.017
catecholamine secretion GO:0050432 15 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
ear morphogenesis GO:0042471 118 0.017
organic anion transport GO:0015711 137 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
negative regulation of interleukin 1 beta production GO:0032691 5 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
regulation of cell adhesion GO:0030155 154 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
cellular response to light stimulus GO:0071482 19 0.017
response to organic cyclic compound GO:0014070 198 0.017
learning GO:0007612 98 0.017
interleukin 1 production GO:0032612 31 0.017
organic acid transport GO:0015849 101 0.017
regulation of amine transport GO:0051952 21 0.017
norepinephrine secretion GO:0048243 2 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
regulation of catecholamine uptake involved in synaptic transmission GO:0051940 2 0.016
cellular response to abiotic stimulus GO:0071214 56 0.016
Mouse
protein ubiquitination GO:0016567 171 0.016
negative regulation of immune system process GO:0002683 209 0.016
Mouse
negative regulation of cellular component organization GO:0051129 194 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
extracellular matrix organization GO:0030198 147 0.016
response to iron ion GO:0010039 4 0.016
forebrain development GO:0030900 302 0.016
cellular homeostasis GO:0019725 240 0.016
neurotransmitter secretion GO:0007269 62 0.016
ras protein signal transduction GO:0007265 77 0.016
nucleoside catabolic process GO:0009164 206 0.016
response to decreased oxygen levels GO:0036293 59 0.016
cellular chemical homeostasis GO:0055082 215 0.016
sulfur compound metabolic process GO:0006790 100 0.016
regulation of norepinephrine secretion GO:0014061 2 0.015
regulation of rhodopsin gene expression GO:0007468 3 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
homeostasis of number of cells GO:0048872 210 0.015
angiogenesis GO:0001525 201 0.015
positive regulation of kinase activity GO:0033674 155 0.015
Mouse
organ growth GO:0035265 117 0.015
apoptotic signaling pathway GO:0097190 306 0.015
neurotransmitter transport GO:0006836 76 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
negative regulation of protein processing GO:0010955 79 0.015
regulation of protein transport GO:0051223 163 0.015
neuron death GO:0070997 154 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
Mouse
circadian sleep wake cycle rem sleep GO:0042747 1 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
negative regulation of peptidase activity GO:0010466 46 0.015
regulation of response to wounding GO:1903034 189 0.015
Mouse
tumor necrosis factor production GO:0032640 50 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
Mouse
inflammatory response GO:0006954 244 0.015
Mouse
calcium ion transmembrane transport GO:0070588 85 0.015
stem cell proliferation GO:0072089 117 0.015
positive regulation of nervous system development GO:0051962 221 0.015
dephosphorylation GO:0016311 129 0.015
negative regulation of protein maturation GO:1903318 79 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
Mouse
inner ear morphogenesis GO:0042472 101 0.014
glucose homeostasis GO:0042593 128 0.014
lymphocyte differentiation GO:0030098 242 0.014
regulation of vasculature development GO:1901342 88 0.014
tissue remodeling GO:0048771 102 0.014
central nervous system neuron axonogenesis GO:0021955 28 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
regulation of peptidase activity GO:0052547 96 0.014
establishment of glial blood brain barrier GO:0060857 2 0.014
regulation of neurotransmitter transport GO:0051588 35 0.014
diencephalon development GO:0021536 63 0.014
positive regulation of angiogenesis GO:0045766 46 0.014
wound healing GO:0042060 157 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
multi organism behavior GO:0051705 62 0.014
tube closure GO:0060606 91 0.014
terpenoid metabolic process GO:0006721 25 0.014
primary neural tube formation GO:0014020 95 0.014
maintenance of location GO:0051235 89 0.014
regulation of tumor necrosis factor production GO:0032680 49 0.014
neural tube closure GO:0001843 90 0.014
extracellular structure organization GO:0043062 148 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
regulation of protein kinase b signaling GO:0051896 56 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.013
intracellular protein transport GO:0006886 204 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
regulation of neuron differentiation GO:0045664 281 0.013
gland development GO:0048732 330 0.013
regulation of neuron projection development GO:0010975 169 0.013
cell adhesion GO:0007155 329 0.013
positive regulation of immune effector process GO:0002699 107 0.013
regulation of metal ion transport GO:0010959 106 0.013
stem cell differentiation GO:0048863 268 0.013
blood vessel morphogenesis GO:0048514 285 0.013
gtp catabolic process GO:0006184 143 0.013
negative regulation of multi organism process GO:0043901 68 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
regulation of interleukin 1 production GO:0032652 26 0.013
regulation of inflammatory response GO:0050727 147 0.013
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.013
cerebellum morphogenesis GO:0021587 42 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
catecholamine transport GO:0051937 21 0.013
regulation of system process GO:0044057 200 0.012
Mouse
nuclear transport GO:0051169 139 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
Mouse
response to oxidative stress GO:0006979 123 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
regulation of multi organism process GO:0043900 111 0.012
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.012
heart process GO:0003015 94 0.012
Mouse
neural retina development GO:0003407 41 0.012
cellular response to oxidative stress GO:0034599 76 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
regulation of homeostatic process GO:0032844 182 0.012
organelle localization GO:0051640 179 0.012
positive regulation of actin nucleation GO:0051127 3 0.012
membrane depolarization GO:0051899 64 0.012
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.012
regulation of cellular ketone metabolic process GO:0010565 66 0.012
vitamin a metabolic process GO:0006776 2 0.012
blood circulation GO:0008015 195 0.012
Mouse
negative regulation of cell activation GO:0050866 111 0.012
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.012
retinal cone cell development GO:0046549 8 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
heart contraction GO:0060047 93 0.012
Mouse
lateral inhibition GO:0046331 1 0.012
cellularization GO:0007349 1 0.012
motor neuron migration GO:0097475 4 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
regulation of actin nucleation GO:0051125 4 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
blood coagulation GO:0007596 76 0.012
rap protein signal transduction GO:0032486 3 0.012
regulation of neurotransmitter secretion GO:0046928 29 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.012
trabecular meshwork development GO:0002930 2 0.012
peptide transport GO:0015833 133 0.012
neuron apoptotic process GO:0051402 142 0.012
ameboidal type cell migration GO:0001667 128 0.012
retinoid metabolic process GO:0001523 24 0.012
regulation of secretion by cell GO:1903530 249 0.012
protein localization to organelle GO:0033365 185 0.012
cofactor metabolic process GO:0051186 80 0.011
interleukin 1 beta production GO:0032611 30 0.011
cell growth GO:0016049 130 0.011
protein catabolic process GO:0030163 221 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
leukocyte apoptotic process GO:0071887 71 0.011
negative regulation of endopeptidase activity GO:0010951 44 0.011
muscle cell differentiation GO:0042692 261 0.011
response to food GO:0032094 17 0.011
skeletal system morphogenesis GO:0048705 203 0.011
response to lipopolysaccharide GO:0032496 128 0.011
Mouse
regulation of microvillus assembly GO:0032534 3 0.011
regulation of body fluid levels GO:0050878 162 0.011
endomembrane system organization GO:0010256 147 0.011
mesodermal cell migration GO:0008078 4 0.011
positive regulation of ion transport GO:0043270 65 0.011
olfactory learning GO:0008355 2 0.011
atp metabolic process GO:0046034 75 0.011
eosinophil migration GO:0072677 3 0.011
glycoprotein metabolic process GO:0009100 116 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
amine transport GO:0015837 21 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
cell activation involved in immune response GO:0002263 126 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
Mouse
negative regulation of transferase activity GO:0051348 85 0.011
small molecule biosynthetic process GO:0044283 132 0.011
hindbrain morphogenesis GO:0021575 46 0.010
striated muscle cell development GO:0055002 125 0.010
positive regulation of endocytosis GO:0045807 42 0.010
photoreceptor cell morphogenesis GO:0008594 3 0.010
gastrulation GO:0007369 116 0.010
positive regulation of nucleotide catabolic process GO:0030813 88 0.010
negative regulation of interleukin 6 production GO:0032715 17 0.010
regulation of b cell activation GO:0050864 81 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
protein localization to nucleus GO:0034504 121 0.010
dopamine secretion GO:0014046 9 0.010
regulation of binding GO:0051098 111 0.010
negative regulation of kinase activity GO:0033673 81 0.010
response to transforming growth factor beta GO:0071559 88 0.010
spinal cord motor neuron migration GO:0097476 4 0.010
negative regulation of cell development GO:0010721 169 0.010
coagulation GO:0050817 78 0.010
regulation of map kinase activity GO:0043405 120 0.010
Mouse
regulation of cell cycle GO:0051726 281 0.010
ossification GO:0001503 216 0.010
cellular aldehyde metabolic process GO:0006081 12 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010

Pde6c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.302
nervous system disease DOID:863 0 0.302
sensory system disease DOID:0050155 0 0.302
eye and adnexa disease DOID:1492 0 0.302
eye disease DOID:5614 0 0.224
retinal disease DOID:5679 0 0.158
retinal degeneration DOID:8466 0 0.148
retinitis pigmentosa DOID:10584 0 0.121
disease of metabolism DOID:0014667 0 0.014
cone rod dystrophy DOID:0050572 0 0.012