Mus musculus

247 known processes

Pdgfb

platelet derived growth factor, B polypeptide

(Aliases: Sis,PDGF-B)

Pdgfb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epithelial tube morphogenesis GO:0060562 303 0.919
Mouse Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.855
ras protein signal transduction GO:0007265 77 0.833
regulation of muscle system process GO:0090257 80 0.792
regulation of map kinase activity GO:0043405 120 0.747
Human
single organism cell adhesion GO:0098602 156 0.741
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.740
positive regulation of cell migration GO:0030335 109 0.739
regulation of cell activation GO:0050865 289 0.732
Human
blood circulation GO:0008015 195 0.732
cell adhesion GO:0007155 329 0.725
Mouse
skeletal system development GO:0001501 356 0.715
small gtpase mediated signal transduction GO:0007264 97 0.706
mapk cascade GO:0000165 281 0.704
Human Mouse
t cell differentiation GO:0030217 174 0.703
skin development GO:0043588 220 0.692
Mouse
positive regulation of cell development GO:0010720 237 0.677
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.654
positive regulation of protein phosphorylation GO:0001934 242 0.648
Human Mouse
positive regulation of smooth muscle cell migration GO:0014911 4 0.639
cell substrate adhesion GO:0031589 130 0.632
Mouse
response to organonitrogen compound GO:0010243 246 0.627
positive regulation of neuron projection development GO:0010976 79 0.623
Mouse
inflammatory response GO:0006954 244 0.621
peptidyl tyrosine phosphorylation GO:0018108 143 0.612
t cell activation GO:0042110 289 0.603
regulation of cell migration GO:0030334 219 0.587
regulation of hydrolase activity GO:0051336 246 0.586
regulation of cellular amine metabolic process GO:0033238 20 0.584
morphogenesis of embryonic epithelium GO:0016331 159 0.581
Mouse
peptidyl amino acid modification GO:0018193 336 0.572
regulation of cell motility GO:2000145 236 0.567
trunk neural crest cell migration GO:0036484 4 0.550
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.548
positive regulation of protein modification process GO:0031401 299 0.541
Human Mouse
positive regulation of cell motility GO:2000147 116 0.531
regulation of rho protein signal transduction GO:0035023 71 0.511
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.511
regulation of cellular catabolic process GO:0031329 242 0.509
cellular amine metabolic process GO:0044106 44 0.504
rho protein signal transduction GO:0007266 32 0.499
nucleoside phosphate metabolic process GO:0006753 338 0.497
regulation of transferase activity GO:0051338 263 0.496
Human
guanosine containing compound catabolic process GO:1901069 144 0.493
purine containing compound metabolic process GO:0072521 311 0.490
heart contraction GO:0060047 93 0.488
Mouse
tube formation GO:0035148 140 0.485
aromatic compound catabolic process GO:0019439 286 0.484
regulation of rho gtpase activity GO:0032319 58 0.446
cellular ketone metabolic process GO:0042180 84 0.446
gland development GO:0048732 330 0.442
immune effector process GO:0002252 321 0.439
cellular lipid metabolic process GO:0044255 323 0.438
Human
phosphatidylinositol mediated signaling GO:0048015 41 0.417
organonitrogen compound catabolic process GO:1901565 264 0.416
multicellular organismal homeostasis GO:0048871 164 0.416
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.416
single organismal cell cell adhesion GO:0016337 131 0.412
Mouse
regulation of organelle organization GO:0033043 289 0.409
Human
smooth muscle cell migration GO:0014909 10 0.409
ameboidal type cell migration GO:0001667 128 0.406
Human Mouse Fly
circulatory system process GO:0003013 197 0.406
regulation of kinase activity GO:0043549 249 0.405
Human
branching involved in salivary gland morphogenesis GO:0060445 26 0.404
neural tube formation GO:0001841 108 0.404
ribose phosphate metabolic process GO:0019693 291 0.400
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.391
Human
cytokine mediated signaling pathway GO:0019221 115 0.390
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.386
stem cell differentiation GO:0048863 268 0.385
bone development GO:0060348 120 0.382
positive regulation of nervous system development GO:0051962 221 0.381
Mouse
anatomical structure homeostasis GO:0060249 145 0.380
Mouse
sympathetic neuron projection extension GO:0097490 4 0.379
purine ribonucleotide metabolic process GO:0009150 290 0.379
morphogenesis of a branching epithelium GO:0061138 193 0.373
purine nucleoside triphosphate catabolic process GO:0009146 203 0.372
regulation of purine nucleotide metabolic process GO:1900542 169 0.371
positive regulation of map kinase activity GO:0043406 84 0.370
Human
glycosyl compound metabolic process GO:1901657 246 0.360
regulation of gtp catabolic process GO:0033124 113 0.359
inositol lipid mediated signaling GO:0048017 41 0.356
regulation of protein serine threonine kinase activity GO:0071900 157 0.352
Human
negative regulation of protein phosphorylation GO:0001933 126 0.351
developmental growth involved in morphogenesis GO:0060560 138 0.349
Mouse
protein secretion GO:0009306 111 0.349
sympathetic neuron projection guidance GO:0097491 4 0.348
negative regulation of phosphorus metabolic process GO:0010563 184 0.346
Human
response to organic cyclic compound GO:0014070 198 0.343
regulation of transmembrane transport GO:0034762 128 0.341
Human
gtp catabolic process GO:0006184 143 0.338
regulation of nucleotide metabolic process GO:0006140 169 0.338
embryonic placenta development GO:0001892 98 0.337
female gonad development GO:0008585 71 0.331
Mouse
regionalization GO:0003002 337 0.324
leukocyte differentiation GO:0002521 342 0.322
epithelial cell migration GO:0010631 63 0.321
Human Mouse Fly
muscle system process GO:0003012 141 0.321
Mouse
nucleoside catabolic process GO:0009164 206 0.317
blood coagulation GO:0007596 76 0.313
Human
regulation of protein kinase activity GO:0045859 232 0.310
Human
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.309
negative regulation of immune system process GO:0002683 209 0.308
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.306
Human
regulation of nucleotide catabolic process GO:0030811 122 0.306
actin filament organization GO:0007015 113 0.304
purine nucleotide metabolic process GO:0006163 302 0.304
peptidyl tyrosine modification GO:0018212 145 0.303
gtp metabolic process GO:0046039 144 0.302
blood vessel morphogenesis GO:0048514 285 0.300
sensory organ morphogenesis GO:0090596 242 0.300
Mouse
leukocyte mediated immunity GO:0002443 174 0.297
cartilage development GO:0051216 140 0.295
branchiomotor neuron axon guidance GO:0021785 7 0.292
granulocyte chemotaxis GO:0071621 39 0.292
embryonic organ morphogenesis GO:0048562 276 0.290
cytokine production GO:0001816 319 0.289
regulation of muscle contraction GO:0006937 49 0.287
purine containing compound catabolic process GO:0072523 213 0.287
sphingolipid metabolic process GO:0006665 45 0.281
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.279
Human
negative regulation of cell migration GO:0030336 59 0.278
neural tube closure GO:0001843 90 0.276
regulation of response to wounding GO:1903034 189 0.273
Human
regulation of actin filament based process GO:0032970 99 0.273
homeostasis of number of cells GO:0048872 210 0.271
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.271
cytokine production involved in immune response GO:0002367 34 0.269
regulation of anatomical structure size GO:0090066 178 0.268
Mouse
regulation of ras gtpase activity GO:0032318 88 0.264
cell matrix adhesion GO:0007160 68 0.262
Mouse
embryonic epithelial tube formation GO:0001838 130 0.261
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.260
Human
eye photoreceptor cell differentiation GO:0001754 41 0.260
Mouse
epithelial tube formation GO:0072175 130 0.259
cardiac cell fate specification GO:0060912 2 0.259
skeletal system morphogenesis GO:0048705 203 0.258
regulation of nucleoside metabolic process GO:0009118 130 0.258
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.258
negative regulation of nervous system development GO:0051961 156 0.258
cell junction assembly GO:0034329 52 0.257
striated muscle contraction GO:0006941 45 0.257
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.254
g protein coupled receptor signaling pathway GO:0007186 243 0.252
regulation of proteolysis GO:0030162 164 0.252
positive regulation of mapk cascade GO:0043410 170 0.252
Human Mouse
vasodilation GO:0042311 28 0.251
purine nucleotide catabolic process GO:0006195 211 0.251
neutrophil migration GO:1990266 37 0.248
positive regulation of hydrolase activity GO:0051345 148 0.248
lung development GO:0030324 164 0.247
Mouse
respiratory tube development GO:0030323 167 0.246
Mouse
regulation of establishment of protein localization GO:0070201 181 0.244
development of primary male sexual characteristics GO:0046546 88 0.244
regulation of cellular component biogenesis GO:0044087 181 0.243
regulation of endothelial cell differentiation GO:0045601 10 0.241
Mouse
lymphocyte differentiation GO:0030098 242 0.238
connective tissue development GO:0061448 179 0.238
negative regulation of intracellular signal transduction GO:1902532 167 0.238
cyclic nucleotide metabolic process GO:0009187 59 0.238
neural tube development GO:0021915 160 0.237
muscle contraction GO:0006936 101 0.236
Mouse
embryonic heart tube development GO:0035050 65 0.235
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.234
epithelial cell development GO:0002064 159 0.234
carbohydrate derivative biosynthetic process GO:1901137 183 0.232
Human Mouse
heart morphogenesis GO:0003007 178 0.232
Mouse
ribonucleotide metabolic process GO:0009259 291 0.231
cardiac septum development GO:0003279 59 0.230
positive regulation of cell adhesion GO:0045785 80 0.229
Mouse
regulation of vasculogenesis GO:2001212 9 0.229
macromolecule catabolic process GO:0009057 281 0.228
cellular amino acid metabolic process GO:0006520 103 0.227
regulation of cellular amino acid metabolic process GO:0006521 5 0.227
ribonucleoside triphosphate catabolic process GO:0009203 199 0.224
ossification GO:0001503 216 0.223
nucleoside metabolic process GO:0009116 246 0.223
vascular process in circulatory system GO:0003018 62 0.222
Mouse
cell fate commitment GO:0045165 210 0.221
nucleotide catabolic process GO:0009166 217 0.221
ribonucleoside metabolic process GO:0009119 245 0.220
actin cytoskeleton organization GO:0030036 220 0.219
ribonucleotide catabolic process GO:0009261 208 0.219
myeloid cell differentiation GO:0030099 233 0.217
Mouse
cation homeostasis GO:0055080 212 0.217
regulation of blood vessel remodeling GO:0060312 3 0.216
glycerolipid metabolic process GO:0046486 122 0.215
Human
negative regulation of cell activation GO:0050866 111 0.215
Human
cerebellar granule cell precursor tangential migration GO:0021935 1 0.213
regulation of ossification GO:0030278 112 0.212
ribonucleoside catabolic process GO:0042454 206 0.212
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.212
leukocyte migration GO:0050900 124 0.210
Human
regulation of mapk cascade GO:0043408 248 0.209
Human Mouse
regulation of osteoblast proliferation GO:0033688 15 0.209
dendritic spine maintenance GO:0097062 4 0.208
negative regulation of cell motility GO:2000146 61 0.208
development of primary sexual characteristics GO:0045137 143 0.208
Mouse
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.206
cellular chemical homeostasis GO:0055082 215 0.206
muscle cell differentiation GO:0042692 261 0.206
Mouse
dendritic cell differentiation GO:0097028 26 0.205
regulation of cardiac cell fate specification GO:2000043 1 0.205
positive regulation of lymphocyte activation GO:0051251 140 0.204
regulation of protein localization GO:0032880 231 0.203
ribonucleoside triphosphate metabolic process GO:0009199 220 0.203
response to decreased oxygen levels GO:0036293 59 0.203
cell junction organization GO:0034330 77 0.203
mesoderm development GO:0007498 100 0.202
Mouse
regulation of lipid metabolic process GO:0019216 118 0.202
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.201
purine ribonucleotide catabolic process GO:0009154 208 0.200
negative regulation of ras protein signal transduction GO:0046580 18 0.200
response to growth factor GO:0070848 198 0.199
male gonad development GO:0008584 88 0.198
negative regulation of secretion GO:0051048 61 0.197
cell migration involved in endocardial cushion formation GO:0003273 3 0.195
ventricular cardiac muscle cell action potential GO:0086005 4 0.195
liver development GO:0001889 66 0.195
microglia development GO:0014005 2 0.194
hair cycle GO:0042633 90 0.193
Mouse
metanephric glomerular mesangium development GO:0072223 3 0.193
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.192
positive regulation of neuron differentiation GO:0045666 141 0.191
Mouse
digestive tract development GO:0048565 190 0.191
Mouse Fly
regulation of cell adhesion GO:0030155 154 0.190
Mouse
regulation of protein transport GO:0051223 163 0.190
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.190
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.189
regulation of cell division GO:0051302 76 0.188
Human
purine nucleoside catabolic process GO:0006152 205 0.188
germ cell development GO:0007281 185 0.186
Fly
lymphocyte proliferation GO:0046651 164 0.185
regulation of cellular response to growth factor stimulus GO:0090287 82 0.185
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.185
Human Mouse
angiogenesis GO:0001525 201 0.185
Mouse
positive regulation of proteolysis GO:0045862 85 0.184
cellular response to organonitrogen compound GO:0071417 145 0.183
cognition GO:0050890 149 0.182
tissue migration GO:0090130 68 0.180
Human Mouse Fly
morphogenesis of an epithelial sheet GO:0002011 27 0.180
bone remodeling GO:0046849 53 0.179
regulation of angiogenesis GO:0045765 81 0.178
Mouse
male sex differentiation GO:0046661 109 0.178
nucleoside triphosphate catabolic process GO:0009143 205 0.177
ventral trunk neural crest cell migration GO:0036486 4 0.177
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.177
leukocyte activation involved in immune response GO:0002366 126 0.176
organic cyclic compound catabolic process GO:1901361 295 0.175
regulation of axon extension GO:0030516 43 0.174
Mouse
ear development GO:0043583 200 0.174
forebrain development GO:0030900 302 0.173
bone resorption GO:0045453 38 0.173
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.172
Human
purine nucleoside metabolic process GO:0042278 241 0.171
myeloid leukocyte migration GO:0097529 57 0.171
Human
positive regulation of protein kinase activity GO:0045860 144 0.168
Human
purine ribonucleoside metabolic process GO:0046128 241 0.167
sensory perception GO:0007600 245 0.167
metal ion homeostasis GO:0055065 189 0.166
tube closure GO:0060606 91 0.165
organ growth GO:0035265 117 0.164
ion transmembrane transport GO:0034220 361 0.164
Human
digestive tract morphogenesis GO:0048546 147 0.162
Fly
positive regulation of neuroblast proliferation GO:0002052 19 0.161
Mouse
heterocycle catabolic process GO:0046700 280 0.161
erythropoietin mediated signaling pathway GO:0038162 1 0.158
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.158
regulation of heart contraction GO:0008016 77 0.158
regulation of blood circulation GO:1903522 93 0.157
stem cell proliferation GO:0072089 117 0.157
Mouse
regulation of embryonic development GO:0045995 71 0.157
primary neural tube formation GO:0014020 95 0.156
retina vasculature development in camera type eye GO:0061298 17 0.156
wnt signaling pathway GO:0016055 188 0.156
carbohydrate derivative catabolic process GO:1901136 231 0.155
positive regulation of chemotaxis GO:0050921 38 0.155
Human Mouse
positive regulation of organelle organization GO:0010638 128 0.153
Human
pro b cell differentiation GO:0002328 10 0.153
biomineral tissue development GO:0031214 64 0.153
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.152
regulation of purine nucleotide catabolic process GO:0033121 122 0.152
cell type specific apoptotic process GO:0097285 268 0.152
Mouse
regulation of lymphocyte activation GO:0051249 240 0.151
cell migration involved in coronary angiogenesis GO:0060981 1 0.151
glycosyl compound catabolic process GO:1901658 206 0.151
membrane lipid metabolic process GO:0006643 53 0.150
nucleobase containing small molecule metabolic process GO:0055086 352 0.150
regulation of lipase activity GO:0060191 15 0.148
regulation of t cell activation GO:0050863 170 0.147
exocrine system development GO:0035272 45 0.147
telencephalon cell migration GO:0022029 55 0.146
transmembrane transport GO:0055085 412 0.145
Human
respiratory system development GO:0060541 190 0.145
Mouse
regulation of system process GO:0044057 200 0.145
amine metabolic process GO:0009308 45 0.145
leukocyte chemotaxis GO:0030595 69 0.145
Human
granulocyte migration GO:0097530 43 0.144
regulation of cytokine production GO:0001817 266 0.143
dna metabolic process GO:0006259 303 0.143
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.143
nucleoside triphosphate metabolic process GO:0009141 230 0.143
purine ribonucleoside catabolic process GO:0046130 205 0.142
innate immune response GO:0045087 157 0.142
second messenger mediated signaling GO:0019932 73 0.142
nucleotide metabolic process GO:0009117 332 0.141
cellular nitrogen compound catabolic process GO:0044270 280 0.140
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.139
male gamete generation GO:0048232 285 0.139
activation of immune response GO:0002253 138 0.139
pallium development GO:0021543 120 0.139
cellular divalent inorganic cation homeostasis GO:0072503 127 0.138
negative regulation of cell proliferation GO:0008285 296 0.138
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.136
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.136
positive regulation of phospholipase activity GO:0010518 3 0.136
gonad development GO:0008406 141 0.136
Mouse
platelet activation GO:0030168 40 0.136
Human
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.134
Human
apoptotic signaling pathway GO:0097190 306 0.134
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.133
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.133
regulation of secretion GO:0051046 274 0.132
muscle cell development GO:0055001 133 0.132
Mouse
calcium ion transport GO:0006816 159 0.131
Human
kidney vasculature development GO:0061440 15 0.130
axon guidance GO:0007411 141 0.129
Mouse
erk1 and erk2 cascade GO:0070371 77 0.128
Human Mouse
developmental pigmentation GO:0048066 40 0.128
protein localization to organelle GO:0033365 185 0.128
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.127
fat cell differentiation GO:0045444 160 0.127
lymphoid progenitor cell differentiation GO:0002320 17 0.126
regulation of leukocyte differentiation GO:1902105 159 0.125
mesendoderm development GO:0048382 3 0.125
negative regulation of neuron differentiation GO:0045665 101 0.125
regulation of smooth muscle cell migration GO:0014910 6 0.124
regulation of stem cell proliferation GO:0072091 78 0.124
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.123
mitotic cell cycle GO:0000278 195 0.123
positive regulation of cytokine production GO:0001819 174 0.122
positive regulation of transferase activity GO:0051347 167 0.121
Human
cerebral cortex cell migration GO:0021795 44 0.121
positive regulation of cell activation GO:0050867 158 0.121
guanosine containing compound metabolic process GO:1901068 144 0.120
cellular response to peptide GO:1901653 92 0.120
cellular response to acid chemical GO:0071229 68 0.120
rhythmic process GO:0048511 174 0.119
Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.119
neural precursor cell proliferation GO:0061351 121 0.119
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.118
Mouse
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.118
epithelial cell proliferation GO:0050673 174 0.118
skeletal muscle organ development GO:0060538 163 0.118
salivary gland development GO:0007431 37 0.117
stem cell maintenance GO:0019827 130 0.116
photoreceptor cell differentiation GO:0046530 52 0.116
Mouse
tissue homeostasis GO:0001894 115 0.116
Mouse
glomerulus development GO:0032835 40 0.116
positive regulation of nucleotide metabolic process GO:0045981 114 0.116
cellular response to lipid GO:0071396 145 0.116
substrate adhesion dependent cell spreading GO:0034446 30 0.115
myeloid leukocyte activation GO:0002274 83 0.115
regulation of kidney development GO:0090183 40 0.115
Human Mouse
regulation of protein catabolic process GO:0042176 108 0.115
negative regulation of axon guidance GO:1902668 8 0.114
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.114
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.113
Mouse
bone morphogenesis GO:0060349 78 0.113
myeloid leukocyte differentiation GO:0002573 119 0.113
positive regulation of kinase activity GO:0033674 155 0.113
Human
phospholipid metabolic process GO:0006644 87 0.112
Human
endocardial cell differentiation GO:0060956 4 0.112
positive regulation of t cell activation GO:0050870 101 0.112
neuron migration GO:0001764 122 0.112
superoxide metabolic process GO:0006801 27 0.111
negative regulation of proteolysis GO:0045861 74 0.111
positive regulation of leukocyte proliferation GO:0070665 73 0.111
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.111
placenta blood vessel development GO:0060674 31 0.111
negative regulation of response to wounding GO:1903035 77 0.111
Human
kit signaling pathway GO:0038109 3 0.110
positive regulation of neural precursor cell proliferation GO:2000179 42 0.110
Mouse
tissue remodeling GO:0048771 102 0.110
regulation of secretion by cell GO:1903530 249 0.110
extracellular structure organization GO:0043062 148 0.110
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.109
glycoprotein biosynthetic process GO:0009101 89 0.109
Mouse
positive regulation of secretion by cell GO:1903532 114 0.109
response to erythropoietin GO:0036017 1 0.108
b cell activation GO:0042113 161 0.108
dendritic cell cytokine production GO:0002371 3 0.108
protein catabolic process GO:0030163 221 0.108
positive regulation of dna biosynthetic process GO:2000573 4 0.108
Human
positive regulation of cell cycle GO:0045787 92 0.107
cell division GO:0051301 120 0.107
Human
negative regulation of cell development GO:0010721 169 0.107
cytokine secretion GO:0050663 72 0.106
response to peptide GO:1901652 136 0.106
negative regulation of protein modification process GO:0031400 163 0.106
positive regulation of cell cycle process GO:0090068 61 0.105
Human
muscle tissue development GO:0060537 308 0.105
Mouse
response to peptide hormone GO:0043434 127 0.105
stem cell development GO:0048864 219 0.105
regulation of blood vessel size GO:0050880 56 0.104
camera type eye development GO:0043010 266 0.104
Mouse
facioacoustic ganglion development GO:1903375 3 0.104
cellular response to cytokine stimulus GO:0071345 189 0.103
cell fate specification GO:0001708 72 0.103
phosphatidylinositol metabolic process GO:0046488 45 0.102
Human
regulation of vesicle mediated transport GO:0060627 139 0.102
g protein coupled receptor internalization GO:0002031 3 0.102
canonical wnt signaling pathway GO:0060070 130 0.101
regulation of vasculature development GO:1901342 88 0.100
Human Mouse
regulation of defense response GO:0031347 233 0.100
regulation of removal of superoxide radicals GO:2000121 4 0.100
neutrophil chemotaxis GO:0030593 36 0.100
positive regulation of ossification GO:0045778 47 0.100
regulation of cytoskeleton organization GO:0051493 122 0.099
response to molecule of bacterial origin GO:0002237 143 0.099
reactive oxygen species metabolic process GO:0072593 84 0.098
Human
response to lipopolysaccharide GO:0032496 128 0.098
fused antrum stage GO:0048165 1 0.098
appendage development GO:0048736 166 0.098
negative regulation of embryonic development GO:0045992 22 0.098
developmental cell growth GO:0048588 84 0.098
Mouse
cell chemotaxis GO:0060326 81 0.097
Human
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.097
regulation of cell cycle GO:0051726 281 0.097
ear morphogenesis GO:0042471 118 0.097
odontogenesis of dentin containing tooth GO:0042475 66 0.096
regulation of tube size GO:0035150 57 0.096
cellular response to stem cell factor stimulus GO:0036216 3 0.095
lipid transport GO:0006869 98 0.095
filopodium assembly GO:0046847 19 0.095
negative regulation of cellular component organization GO:0051129 194 0.095
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.095
alpha beta t cell activation GO:0046631 91 0.094
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.094
axonogenesis GO:0007409 274 0.094
Mouse
regulation of phospholipase c activity GO:1900274 3 0.094
negative regulation of phosphorylation GO:0042326 166 0.094
response to radiation GO:0009314 165 0.093
Fly
chemotaxis GO:0006935 247 0.093
Human Mouse
chondrocyte differentiation GO:0002062 72 0.093
negative regulation of rho protein signal transduction GO:0035024 7 0.092
wound healing GO:0042060 157 0.092
Human
development of primary female sexual characteristics GO:0046545 73 0.092
Mouse
regulation of b cell activation GO:0050864 81 0.092
steroid metabolic process GO:0008202 119 0.092
renal system process GO:0003014 48 0.091
labyrinthine layer development GO:0060711 49 0.091
regulation of hormone levels GO:0010817 211 0.091
protein maturation GO:0051604 176 0.091
positive regulation of rho gtpase activity GO:0032321 41 0.091
microtubule based process GO:0007017 236 0.091
cellular metal ion homeostasis GO:0006875 151 0.090
muscle cell migration GO:0014812 19 0.090
cellular response to growth factor stimulus GO:0071363 197 0.089
developmental maturation GO:0021700 193 0.089
Mouse
organelle fission GO:0048285 170 0.089
Human
myeloid cell homeostasis GO:0002262 114 0.088
Mouse
urogenital system development GO:0001655 261 0.088
regulation of cellular response to stress GO:0080135 159 0.087
erbb signaling pathway GO:0038127 32 0.087
negative regulation of growth GO:0045926 99 0.086
regulation of cell shape GO:0008360 39 0.086
hepaticobiliary system development GO:0061008 67 0.086
regulation of nuclear division GO:0051783 56 0.085
Human
divalent inorganic cation transport GO:0072511 178 0.085
Human
regulation of leukocyte proliferation GO:0070663 121 0.085
ovarian follicle development GO:0001541 40 0.084
Mouse
positive regulation of protein transport GO:0051222 93 0.084
organic acid transport GO:0015849 101 0.084
limbic system development GO:0021761 72 0.084
face development GO:0060324 38 0.084
regulation of cytokine secretion GO:0050707 61 0.084
telencephalon development GO:0021537 186 0.084
regulation of hippo signaling GO:0035330 1 0.084
regulation of cell projection organization GO:0031344 206 0.083
Mouse
calcium ion homeostasis GO:0055074 127 0.083
negative regulation of cell fate specification GO:0009996 4 0.083
neuroepithelial cell differentiation GO:0060563 37 0.083
protein import into nucleus GO:0006606 95 0.082
spermatid differentiation GO:0048515 115 0.082
epidermal growth factor receptor signaling pathway GO:0007173 28 0.081
positive regulation of growth GO:0045927 104 0.081
Mouse
leukocyte proliferation GO:0070661 172 0.081
striated muscle cell development GO:0055002 125 0.081
Mouse
pigmentation GO:0043473 71 0.081
digestive system development GO:0055123 200 0.080
Mouse Fly
positive regulation of ion transport GO:0043270 65 0.080
Human
negative regulation of cell adhesion GO:0007162 45 0.080
Mouse
antigen receptor mediated signaling pathway GO:0050851 64 0.080

Pdgfb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.137
nervous system disease DOID:863 0 0.137