Mus musculus

221 known processes

Pdgfra

platelet derived growth factor receptor, alpha polypeptide

(Aliases: CD140a,AI115593,Pdgfr-2)

Pdgfra biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
smooth muscle tissue development GO:0048745 22 1.000
Mouse
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 1.000
trachea formation GO:0060440 3 1.000
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 1.000
embryonic skeletal system development GO:0048706 120 1.000
kidney development GO:0001822 213 1.000
glomerulus morphogenesis GO:0072102 10 1.000
ovulation cycle GO:0042698 59 1.000
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 1.000
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.999
embryonic skeletal system morphogenesis GO:0048704 91 0.999
regulation of cartilage development GO:0061035 44 0.999
skeletal system development GO:0001501 356 0.999
trophectodermal cellular morphogenesis GO:0001831 3 0.999
stem cell development GO:0048864 219 0.999
mesenchyme development GO:0060485 152 0.999
axial mesodermal cell fate commitment GO:0048322 1 0.999
axon guidance GO:0007411 141 0.999
embryonic organ morphogenesis GO:0048562 276 0.999
renal system development GO:0072001 225 0.999
female sex differentiation GO:0046660 84 0.999
cell proliferation involved in metanephros development GO:0072203 9 0.999
Mouse
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.999
negative regulation of prostatic bud formation GO:0060686 4 0.998
skeletal system morphogenesis GO:0048705 203 0.998
bone development GO:0060348 120 0.998
ovarian follicle development GO:0001541 40 0.998
Mouse
stem cell differentiation GO:0048863 268 0.998
Human Mouse
cellular response to growth factor stimulus GO:0071363 197 0.997
renal system vasculature development GO:0061437 15 0.997
muscle cell development GO:0055001 133 0.997
chondrocyte differentiation GO:0002062 72 0.997
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.997
regulation of endothelial cell differentiation GO:0045601 10 0.997
Mouse
palate development GO:0060021 76 0.996
embryonic skeletal joint morphogenesis GO:0060272 11 0.996
appendage morphogenesis GO:0035107 149 0.995
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.995
tendon cell differentiation GO:0035990 4 0.995
glomerulus vasculature morphogenesis GO:0072103 6 0.994
ureteric bud development GO:0001657 94 0.994
pyramidal neuron migration GO:0021852 1 0.994
roof plate formation GO:0021509 1 0.994
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.994
stem cell maintenance GO:0019827 130 0.993
retina vasculature development in camera type eye GO:0061298 17 0.993
blood vessel morphogenesis GO:0048514 285 0.993
metanephric capsule specification GO:0072267 1 0.993
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.993
Mouse Fly
neuron projection guidance GO:0097485 141 0.993
lateral mesoderm morphogenesis GO:0048369 3 0.992
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.992
Mouse
ameboidal type cell migration GO:0001667 128 0.992
Mouse Fly
neural crest cell migration GO:0001755 32 0.992
camera type eye development GO:0043010 266 0.992
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.992
Mouse
estrogen metabolic process GO:0008210 8 0.992
urogenital system development GO:0001655 261 0.992
sensory organ morphogenesis GO:0090596 242 0.992
hindbrain tangential cell migration GO:0021934 2 0.992
bone morphogenesis GO:0060349 78 0.992
corticotropin hormone secreting cell differentiation GO:0060128 3 0.991
regulation of cell adhesion GO:0030155 154 0.991
face morphogenesis GO:0060325 29 0.991
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.991
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.990
mesenchymal cell differentiation GO:0048762 107 0.990
positive regulation of bmp signaling pathway GO:0030513 23 0.990
Mouse
luteinization GO:0001553 8 0.990
positive regulation of nervous system development GO:0051962 221 0.989
development of primary female sexual characteristics GO:0046545 73 0.988
fused antrum stage GO:0048165 1 0.988
heart trabecula formation GO:0060347 14 0.988
cell proliferation involved in kidney development GO:0072111 14 0.988
Mouse
chondrocyte development GO:0002063 24 0.987
regulation of bmp signaling pathway GO:0030510 60 0.987
Mouse
female gonad development GO:0008585 71 0.987
axonogenesis GO:0007409 274 0.987
negative regulation of cartilage development GO:0061037 17 0.986
epithelial tube morphogenesis GO:0060562 303 0.986
Mouse Fly
prostate gland morphogenesis GO:0060512 32 0.986
embryonic skeletal joint development GO:0072498 13 0.986
response to growth factor GO:0070848 198 0.986
mesenchymal cell proliferation GO:0010463 44 0.986
Mouse
regulation of astrocyte differentiation GO:0048710 20 0.985
branching involved in ureteric bud morphogenesis GO:0001658 56 0.984
positive regulation of axon extension GO:0045773 20 0.983
negative regulation of cell development GO:0010721 169 0.981
respiratory tube development GO:0030323 167 0.980
digestive tract development GO:0048565 190 0.980
positive regulation of endothelial cell differentiation GO:0045603 7 0.980
floor plate morphogenesis GO:0033505 3 0.979
mesonephric tubule development GO:0072164 94 0.979
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.979
positive regulation of endothelial cell proliferation GO:0001938 17 0.978
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.978
locus ceruleus development GO:0021703 1 0.978
tendon formation GO:0035992 4 0.978
neuroepithelial cell differentiation GO:0060563 37 0.978
Mouse
endochondral bone morphogenesis GO:0060350 50 0.977
maternal placenta development GO:0001893 20 0.977
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.977
Mouse
regionalization GO:0003002 337 0.977
muscle tissue development GO:0060537 308 0.977
cell fate commitment GO:0045165 210 0.975
Mouse
ear development GO:0043583 200 0.975
Rat
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.975
odontogenesis GO:0042476 78 0.975
negative regulation of cell fate specification GO:0009996 4 0.974
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.974
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.973
lateral mesoderm formation GO:0048370 3 0.973
regulation of mesenchymal cell proliferation GO:0010464 37 0.972
Mouse
digestive system development GO:0055123 200 0.972
stem cell proliferation GO:0072089 117 0.971
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.971
rhythmic process GO:0048511 174 0.969
negative regulation of endodermal cell differentiation GO:1903225 1 0.967
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.967
kidney morphogenesis GO:0060993 83 0.967
salivary gland morphogenesis GO:0007435 33 0.966
Fly
negative regulation of cell proliferation GO:0008285 296 0.966
Mouse
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.965
mesonephros development GO:0001823 97 0.965
regulation of endodermal cell fate specification GO:0042663 2 0.965
limb development GO:0060173 166 0.965
ventricular zone neuroblast division GO:0021847 3 0.964
lung development GO:0030324 164 0.964
regulation of organ morphogenesis GO:2000027 144 0.963
nephron tubule morphogenesis GO:0072078 68 0.962
negative regulation of gastrulation GO:2000542 3 0.962
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.961
cell adhesion GO:0007155 329 0.960
Human Mouse
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.960
positive regulation of tendon cell differentiation GO:2001051 1 0.960
branching involved in salivary gland morphogenesis GO:0060445 26 0.959
neural tube closure GO:0001843 90 0.959
proteoglycan metabolic process GO:0006029 38 0.959
axial mesoderm formation GO:0048320 3 0.959
regulation of protein serine threonine kinase activity GO:0071900 157 0.958
Mouse
epithelial cell proliferation GO:0050673 174 0.957
Mouse
kidney vasculature morphogenesis GO:0061439 7 0.957
negative regulation of chondrocyte differentiation GO:0032331 13 0.957
nephron tubule development GO:0072080 84 0.957
heart field specification GO:0003128 6 0.955
glomerulus vasculature development GO:0072012 14 0.955
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.953
branching involved in prostate gland morphogenesis GO:0060442 15 0.953
regulation of mapk cascade GO:0043408 248 0.953
Human Mouse Fly
cardiac muscle cell development GO:0055013 39 0.952
negative regulation of neuron differentiation GO:0045665 101 0.952
developmental maturation GO:0021700 193 0.951
Mouse
angiogenesis GO:0001525 201 0.951
positive regulation of cell development GO:0010720 237 0.951
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.951
neuron migration GO:0001764 122 0.950
response to transforming growth factor beta GO:0071559 88 0.950
mesonephric tubule morphogenesis GO:0072171 63 0.949
ventricular cardiac muscle cell development GO:0055015 11 0.949
response to cholesterol GO:0070723 4 0.949
ventricular cardiac muscle cell differentiation GO:0055012 17 0.949
positive regulation of mapk cascade GO:0043410 170 0.948
Human Mouse Fly
mesendoderm development GO:0048382 3 0.948
regulation of map kinase activity GO:0043405 120 0.944
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.943
bmp signaling pathway GO:0030509 93 0.940
Mouse
axial mesodermal cell fate specification GO:0048327 1 0.940
nephron development GO:0072006 109 0.940
replacement ossification GO:0036075 26 0.937
hindlimb morphogenesis GO:0035137 42 0.937
cell proliferation in midbrain GO:0033278 2 0.937
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.937
glomerular mesangial cell development GO:0072144 3 0.933
morphogenesis of a branching epithelium GO:0061138 193 0.932
Mouse
fat cell differentiation GO:0045444 160 0.932
regulation of mesodermal cell fate specification GO:0042661 5 0.932
glomerular mesangium development GO:0072109 5 0.931
Mouse
placenta development GO:0001890 140 0.930
inner ear receptor cell differentiation GO:0060113 61 0.930
aorta morphogenesis GO:0035909 22 0.930
Mouse
regulation of morphogenesis of a branching structure GO:0060688 53 0.928
mesenchymal cell proliferation involved in ureteric bud development GO:0072138 3 0.927
endocardium development GO:0003157 10 0.927
Mouse
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.927
spermatogenesis GO:0007283 284 0.927
Mouse
hormone metabolic process GO:0042445 86 0.926
growth plate cartilage chondrocyte development GO:0003431 3 0.926
pathway restricted smad protein phosphorylation GO:0060389 10 0.926
kidney vasculature development GO:0061440 15 0.926
nephron epithelium morphogenesis GO:0072088 68 0.924
exocrine system development GO:0035272 45 0.924
Fly
regulation of endodermal cell differentiation GO:1903224 2 0.921
neural crest cell development GO:0014032 48 0.920
response to sterol GO:0036314 4 0.919
mesenchymal cell development GO:0014031 93 0.919
regulation of neuron differentiation GO:0045664 281 0.919
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.919
Human Mouse
negative regulation of nervous system development GO:0051961 156 0.918
cardiac endothelial cell differentiation GO:0003348 4 0.917
retinal ganglion cell axon guidance GO:0031290 18 0.916
cartilage condensation GO:0001502 18 0.916
growth plate cartilage development GO:0003417 14 0.916
single organismal cell cell adhesion GO:0016337 131 0.915
Human Mouse
nephrogenic mesenchyme development GO:0072076 3 0.914
cell chemotaxis GO:0060326 81 0.914
hair follicle development GO:0001942 85 0.914
kidney epithelium development GO:0072073 121 0.914
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.913
oogenesis stage GO:0022605 3 0.912
positive regulation of epithelial cell proliferation GO:0050679 68 0.911
Mouse
positive regulation of glial cell differentiation GO:0045687 21 0.911
left lung development GO:0060459 4 0.911
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.910
formation of radial glial scaffolds GO:0021943 4 0.910
face development GO:0060324 38 0.909
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.908
regulation of epithelial cell proliferation GO:0050678 141 0.907
Mouse
regulation of stem cell differentiation GO:2000736 50 0.906
Human
primary neural tube formation GO:0014020 95 0.905
embryonic viscerocranium morphogenesis GO:0048703 8 0.905
negative regulation of axon extension GO:0030517 19 0.902
mechanoreceptor differentiation GO:0042490 67 0.902
negative regulation of endothelial cell differentiation GO:0045602 2 0.901
axonogenesis involved in innervation GO:0060385 5 0.900
gland development GO:0048732 330 0.899
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.898
negative regulation of cardiac muscle tissue development GO:0055026 8 0.897
positive regulation of transcription by glucose GO:0046016 3 0.896
regulation of glial cell differentiation GO:0045685 41 0.896
cell proliferation in hindbrain GO:0021534 10 0.894
extrinsic apoptotic signaling pathway GO:0097191 126 0.893
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.893
head morphogenesis GO:0060323 34 0.893
regulation of chondrocyte differentiation GO:0032330 33 0.893
cell fate specification GO:0001708 72 0.892
negative regulation of stem cell maintenance GO:1902455 4 0.892
heart morphogenesis GO:0003007 178 0.891
regulation of axon extension GO:0030516 43 0.890
notch signaling pathway GO:0007219 71 0.890
cell migration involved in gastrulation GO:0042074 13 0.889
lateral mesodermal cell differentiation GO:0048371 3 0.888
erk1 and erk2 cascade GO:0070371 77 0.887
Human Mouse
negative regulation of kidney development GO:0090185 15 0.886
lung morphogenesis GO:0060425 50 0.885
ossification GO:0001503 216 0.884
cloacal septation GO:0060197 2 0.884
regulation of odontogenesis GO:0042481 18 0.882
auditory receptor cell fate determination GO:0042668 3 0.882
regulation of biomineral tissue development GO:0070167 33 0.881
mammary gland morphogenesis GO:0060443 54 0.880
response to dietary excess GO:0002021 18 0.880
morphogenesis of embryonic epithelium GO:0016331 159 0.879
prostate gland development GO:0030850 48 0.879
neural tube formation GO:0001841 108 0.878
mesonephric epithelium development GO:0072163 94 0.877
regulation of gastrulation GO:0010470 16 0.877
bmp signaling pathway involved in heart development GO:0061312 2 0.877
smoothened signaling pathway GO:0007224 105 0.875
mesangial cell differentiation GO:0072007 4 0.874
regulation of hormone levels GO:0010817 211 0.874
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.874
establishment of neuroblast polarity GO:0045200 1 0.874
regulation of cell cycle GO:0051726 281 0.873
Mouse
forebrain cell migration GO:0021885 58 0.872
metanephros development GO:0001656 79 0.872
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.872
morphogenesis of a branching structure GO:0001763 203 0.871
Mouse
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.871
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.870
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.869
Mouse
regulation of homeostatic process GO:0032844 182 0.867
germ line stem cell division GO:0042078 2 0.866
negative regulation of epithelial cell proliferation GO:0050680 64 0.866
metanephric mesenchyme morphogenesis GO:0072133 4 0.865
metanephric glomerular mesangium development GO:0072223 3 0.865
Mouse
noradrenergic neuron differentiation GO:0003357 6 0.864
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.864
Mouse
astrocyte fate commitment GO:0060018 4 0.862
regulation of vasculature development GO:1901342 88 0.862
Mouse
regulation of myoblast differentiation GO:0045661 29 0.862
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.861
axon extension involved in axon guidance GO:0048846 14 0.859
development of primary sexual characteristics GO:0045137 143 0.858
lateral mesodermal cell fate commitment GO:0048372 2 0.857
embryonic placenta development GO:0001892 98 0.857
prostate gland epithelium morphogenesis GO:0060740 31 0.857
nephron morphogenesis GO:0072028 69 0.855
cerebral cortex tangential migration GO:0021800 7 0.853
endoderm development GO:0007492 45 0.847
blastocyst development GO:0001824 80 0.844
regulation of branching involved in prostate gland morphogenesis GO:0060687 7 0.842
positive regulation of chemotaxis GO:0050921 38 0.841
Mouse
chondrocyte hypertrophy GO:0003415 4 0.839
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.839
regulation of cardiac muscle tissue development GO:0055024 31 0.839
endodermal cell fate specification GO:0001714 4 0.838
carbon catabolite activation of transcription GO:0045991 4 0.836
single organism cell adhesion GO:0098602 156 0.834
Human Mouse
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.834
regulation of glomerular mesangial cell proliferation GO:0072124 1 0.832
regulation of tolerance induction to self antigen GO:0002649 1 0.828
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.828
regulation of pathway restricted smad protein phosphorylation GO:0060393 6 0.827
cardiac muscle tissue development GO:0048738 130 0.825
cardiac muscle tissue growth GO:0055017 37 0.825
globus pallidus development GO:0021759 2 0.825
neural crest cell differentiation GO:0014033 54 0.824
biomineral tissue development GO:0031214 64 0.823
otic placode formation GO:0043049 1 0.821
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.820
signal transduction in absence of ligand GO:0038034 55 0.819
carbon catabolite repression of transcription GO:0045013 1 0.818
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.818
metanephric glomerulus development GO:0072224 13 0.817
somitogenesis GO:0001756 69 0.816
gastrulation GO:0007369 116 0.816
medulla oblongata development GO:0021550 3 0.815
forebrain morphogenesis GO:0048853 17 0.812
metanephric comma shaped body morphogenesis GO:0072278 1 0.810
connective tissue development GO:0061448 179 0.810
Mouse
embryonic nail plate morphogenesis GO:0035880 3 0.808
mesodermal cell fate commitment GO:0001710 17 0.808
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.808
Mouse
limb morphogenesis GO:0035108 149 0.805
neural tube patterning GO:0021532 43 0.803
neuron projection extension GO:1990138 64 0.802
cellular response to cholesterol GO:0071397 2 0.802
glomerular mesangial cell differentiation GO:0072008 3 0.802
tube formation GO:0035148 140 0.801
bone mineralization GO:0030282 54 0.801
regulation of cell migration GO:0030334 219 0.800
Human Mouse
tissue remodeling GO:0048771 102 0.800
Mouse
germ cell development GO:0007281 185 0.798
Mouse Fly
muscle cell proliferation GO:0033002 52 0.798
Mouse
axial mesodermal cell differentiation GO:0048321 1 0.795
brain morphogenesis GO:0048854 32 0.794
growth plate cartilage chondrocyte growth GO:0003430 2 0.793
osteoblast development GO:0002076 17 0.793
regulation of aldosterone metabolic process GO:0032344 1 0.792
cerebellar granule cell precursor proliferation GO:0021930 10 0.791
negative regulation of immature t cell proliferation GO:0033087 3 0.790
regulation of kidney development GO:0090183 40 0.789
Mouse
regulation of cell size GO:0008361 72 0.789
inner cell mass cellular morphogenesis GO:0001828 1 0.789
renal system vasculature morphogenesis GO:0061438 7 0.789
regulation of reactive oxygen species metabolic process GO:2000377 40 0.788
Mouse
kidney mesenchyme development GO:0072074 14 0.788
negative regulation of astrocyte differentiation GO:0048712 10 0.785
regulation of kinase activity GO:0043549 249 0.785
Human Mouse
primitive streak formation GO:0090009 10 0.784
mesenchyme morphogenesis GO:0072132 32 0.784
positive regulation of growth GO:0045927 104 0.782
inflammatory response GO:0006954 244 0.779
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.776
embryonic heart tube morphogenesis GO:0003143 51 0.773
steroid metabolic process GO:0008202 119 0.770
positive regulation of neuron apoptotic process GO:0043525 25 0.769
hair cycle GO:0042633 90 0.769
endodermal cell fate commitment GO:0001711 12 0.769
positive regulation of cell migration GO:0030335 109 0.768
Human Mouse
vascular wound healing GO:0061042 3 0.767
organ growth GO:0035265 117 0.765
oocyte axis specification GO:0007309 2 0.763
embryonic appendage morphogenesis GO:0035113 126 0.762
positive regulation of stem cell proliferation GO:2000648 59 0.761
Mouse
heart trabecula morphogenesis GO:0061384 26 0.760
regulation of cell projection organization GO:0031344 206 0.759
metanephric nephron tubule formation GO:0072289 4 0.757
positive regulation of dna templated transcription elongation GO:0032786 2 0.757
positive regulation of neuroblast proliferation GO:0002052 19 0.756
tendon development GO:0035989 6 0.755
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.755
c21 steroid hormone biosynthetic process GO:0006700 3 0.755
regulation of cellular amine metabolic process GO:0033238 20 0.754
ureteric bud morphogenesis GO:0060675 62 0.753
extracellular matrix organization GO:0030198 147 0.753
metanephric capsule formation GO:0072266 1 0.753
embryonic heart tube formation GO:0003144 1 0.752
branching morphogenesis of an epithelial tube GO:0048754 159 0.752
Mouse
epithelial tube formation GO:0072175 130 0.751
cerebellum development GO:0021549 77 0.751
cartilage development GO:0051216 140 0.749
negative regulation of endodermal cell fate specification GO:0042664 1 0.748
endocrine system development GO:0035270 98 0.748
embryonic hemopoiesis GO:0035162 23 0.747
Mouse Fly
cellular response to erythropoietin GO:0036018 1 0.746
Mouse
negative regulation of kinase activity GO:0033673 81 0.744
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.741
prostatic bud formation GO:0060513 10 0.740
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.739
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.734
cell cell signaling involved in cell fate commitment GO:0045168 35 0.734
inner ear morphogenesis GO:0042472 101 0.733
spermatid development GO:0007286 108 0.731
Mouse
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.731
forebrain development GO:0030900 302 0.729
endocardial cell differentiation GO:0060956 4 0.726
cellular response to organic cyclic compound GO:0071407 87 0.722
negative regulation of striated muscle cell differentiation GO:0051154 14 0.722
embryonic limb morphogenesis GO:0030326 126 0.719
smooth muscle cell chemotaxis GO:0071670 2 0.718
Mouse
mineralocorticoid biosynthetic process GO:0006705 1 0.717
ear morphogenesis GO:0042471 118 0.710
positive regulation of apoptotic process GO:0043065 217 0.709
olfactory bulb interneuron development GO:0021891 7 0.706
negative regulation of cell adhesion GO:0007162 45 0.703
epithelial cell migration GO:0010631 63 0.702
Mouse Fly
cranial suture morphogenesis GO:0060363 8 0.702
diencephalon development GO:0021536 63 0.699
positive regulation of odontogenesis GO:0042482 4 0.698
regulation of angiogenesis GO:0045765 81 0.697
Mouse
respiratory system development GO:0060541 190 0.697
melanocyte migration GO:0097324 2 0.693
Mouse
positive regulation of p38mapk cascade GO:1900745 1 0.691
regulation of vascular wound healing GO:0061043 2 0.691
positive regulation of angiogenesis GO:0045766 46 0.686
Mouse
negative regulation of glomerular mesangial cell proliferation GO:0072125 1 0.684
lung induction GO:0060492 3 0.684
response to oxygen levels GO:0070482 62 0.683
Mouse Rat
orbitofrontal cortex development GO:0021769 2 0.683
positive regulation of protein phosphorylation GO:0001934 242 0.683
Mouse
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.683
regulation of bone mineralization GO:0030500 31 0.680
branching involved in labyrinthine layer morphogenesis GO:0060670 9 0.680
inhibition of neuroepithelial cell differentiation GO:0002085 2 0.676
regulation of cellular response to growth factor stimulus GO:0090287 82 0.676
kidney mesenchyme morphogenesis GO:0072131 4 0.675
leydig cell differentiation GO:0033327 10 0.675
molting cycle GO:0042303 90 0.674
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.673
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.673
male sex differentiation GO:0046661 109 0.672
extracellular structure organization GO:0043062 148 0.671
positive regulation of dendrite development GO:1900006 21 0.671
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.671
regulation of transferase activity GO:0051338 263 0.671
Human Mouse
cellular response to thyroid hormone stimulus GO:0097067 1 0.670
Mouse
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.669
cell migration involved in coronary angiogenesis GO:0060981 1 0.668
Mouse
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.668
hematopoietic progenitor cell differentiation GO:0002244 143 0.668
endoderm formation GO:0001706 20 0.667
male gonad development GO:0008584 88 0.666
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.665
morphogenesis of an epithelial fold GO:0060571 28 0.665
regulation of mitotic cell cycle GO:0007346 126 0.664
Mouse
response to extracellular stimulus GO:0009991 127 0.662
determination of heart left right asymmetry GO:0061371 48 0.661
glomerular capillary formation GO:0072104 6 0.658
positive regulation of cellular amine metabolic process GO:0033240 5 0.657
lateral mesodermal cell fate specification GO:0048377 2 0.656
embryonic placenta morphogenesis GO:0060669 25 0.655
cardiac muscle tissue morphogenesis GO:0055008 44 0.654
positive regulation of osteoblast proliferation GO:0033690 9 0.653
striated muscle cell development GO:0055002 125 0.653
positive regulation of vascular wound healing GO:0035470 1 0.652
mesoderm structural organization GO:0048338 1 0.650
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.649
telencephalon cell migration GO:0022029 55 0.648
regulation of heart morphogenesis GO:2000826 22 0.647
cardiogenic plate morphogenesis GO:0003142 1 0.646
epithelial mesenchymal cell signaling GO:0060684 7 0.645
cardiac chamber development GO:0003205 108 0.644
digestive tract morphogenesis GO:0048546 147 0.639
noradrenergic neuron development GO:0003358 3 0.638
regulation of cardioblast differentiation GO:0051890 3 0.637
endothelial cell differentiation GO:0045446 41 0.637
Mouse
mitotic cell cycle GO:0000278 195 0.636
Mouse Fly
neural fold formation GO:0001842 7 0.635
negative regulation of glial cell proliferation GO:0060253 4 0.634
regulation of neuroblast proliferation GO:1902692 27 0.634
muscle cell differentiation GO:0042692 261 0.632
bronchus morphogenesis GO:0060434 2 0.631
bmp signaling pathway involved in mesodermal cell fate specification GO:0060803 1 0.631
regulation of smooth muscle cell differentiation GO:0051150 9 0.631
positive regulation of cardioblast differentiation GO:0051891 3 0.629
positive regulation of protein modification process GO:0031401 299 0.628
Mouse
regulation of cell motility GO:2000145 236 0.626
Human Mouse
renal tubule development GO:0061326 87 0.626
Fly
positive regulation of neuron projection development GO:0010976 79 0.625
positive regulation of kidney development GO:0090184 28 0.623
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.619
glial cell differentiation GO:0010001 131 0.618
positive regulation of phospholipase activity GO:0010518 3 0.616
Human
liver development GO:0001889 66 0.616
positive regulation of chondrocyte differentiation GO:0032332 13 0.615
regulation of anatomical structure size GO:0090066 178 0.615
axis elongation GO:0003401 30 0.614
cerebral cortex cell migration GO:0021795 44 0.612
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.611
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.609
regulation of gliogenesis GO:0014013 50 0.608
neural tube development GO:0021915 160 0.608
mesoderm development GO:0007498 100 0.608
cell maturation GO:0048469 127 0.607
Mouse
cell division GO:0051301 120 0.606
Mouse
chemotaxis GO:0006935 247 0.605
ascending aorta morphogenesis GO:0035910 3 0.602
response to organic cyclic compound GO:0014070 198 0.602
Rat

Pdgfra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org