Mus musculus

353 known processes

Pdgfrb

platelet derived growth factor receptor, beta polypeptide

(Aliases: Pdgfr,AI528809,CD140b)

Pdgfrb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
sprouting angiogenesis GO:0002040 26 0.996
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.995
Human Mouse Rat
muscle tissue development GO:0060537 308 0.995
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.991
Mouse
formation of radial glial scaffolds GO:0021943 4 0.990
venous blood vessel morphogenesis GO:0048845 7 0.990
vascular endothelial growth factor signaling pathway GO:0038084 10 0.982
Human Mouse
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.981
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.978
positive regulation of axon extension GO:0045773 20 0.978
metanephric glomerular mesangium development GO:0072223 3 0.970
epithelial cell migration GO:0010631 63 0.970
Mouse Fly
tissue migration GO:0090130 68 0.970
Mouse Fly
regulation of removal of superoxide radicals GO:2000121 4 0.965
embryonic organ morphogenesis GO:0048562 276 0.963
Mouse
positive regulation of cell migration GO:0030335 109 0.958
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.953
negative regulation of cell migration GO:0030336 59 0.948
substrate dependent cell migration GO:0006929 18 0.948
cell migration involved in endocardial cushion formation GO:0003273 3 0.948
vegf activated neuropilin signaling pathway GO:0038190 2 0.947
kidney development GO:0001822 213 0.945
glomerulus development GO:0032835 40 0.941
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.935
cell adhesion GO:0007155 329 0.933
Mouse
mesangial cell differentiation GO:0072007 4 0.933
cardiac muscle fiber development GO:0048739 4 0.930
retina vasculature development in camera type eye GO:0061298 17 0.929
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.927
cell migration involved in sprouting angiogenesis GO:0002042 9 0.924
Mouse
blood vessel morphogenesis GO:0048514 285 0.923
urogenital system development GO:0001655 261 0.923
negative regulation of cell motility GO:2000146 61 0.920
response to growth factor GO:0070848 198 0.920
Human Mouse Rat
response to transforming growth factor beta GO:0071559 88 0.916
cardiocyte differentiation GO:0035051 87 0.915
endothelial cell migration GO:0043542 44 0.910
Mouse
camera type eye development GO:0043010 266 0.909
blood vessel endothelial cell migration GO:0043534 23 0.903
Mouse
kidney vasculature development GO:0061440 15 0.902
metanephric glomerular endothelium development GO:0072264 1 0.901
striated muscle tissue development GO:0014706 293 0.900
neuropilin signaling pathway GO:0038189 2 0.898
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.895
endothelial cell proliferation GO:0001935 27 0.893
digestive tract development GO:0048565 190 0.892
Mouse Fly
digestive tract morphogenesis GO:0048546 147 0.887
Mouse Fly
cell substrate adhesion GO:0031589 130 0.886
glomerular mesangial cell differentiation GO:0072008 3 0.877
regulation of cell substrate adhesion GO:0010810 73 0.874
glomerular mesangial cell development GO:0072144 3 0.870
branching involved in salivary gland morphogenesis GO:0060445 26 0.861
retinal blood vessel morphogenesis GO:0061304 3 0.859
regulation of system process GO:0044057 200 0.857
skeletal system morphogenesis GO:0048705 203 0.851
salivary gland development GO:0007431 37 0.849
Fly
renal system vasculature development GO:0061437 15 0.846
positive regulation of nervous system development GO:0051962 221 0.844
connective tissue development GO:0061448 179 0.837
regulation of cell migration GO:0030334 219 0.831
vascular process in circulatory system GO:0003018 62 0.829
lung development GO:0030324 164 0.824
Mouse
cardiac muscle tissue development GO:0048738 130 0.823
sensory organ morphogenesis GO:0090596 242 0.819
positive regulation of angiogenesis GO:0045766 46 0.816
Mouse
digestive system development GO:0055123 200 0.815
Mouse Fly
extracellular structure organization GO:0043062 148 0.807
Mouse
embryonic placenta development GO:0001892 98 0.802
positive regulation of cell adhesion GO:0045785 80 0.799
metanephric mesangial cell differentiation GO:0072209 1 0.799
skeletal system development GO:0001501 356 0.797
skeletal muscle organ development GO:0060538 163 0.794
heart trabecula formation GO:0060347 14 0.789
regulation of anatomical structure size GO:0090066 178 0.789
negative regulation of rho protein signal transduction GO:0035024 7 0.787
regulation of reactive oxygen species metabolic process GO:2000377 40 0.785
cellular response to vascular endothelial growth factor stimulus GO:0035924 11 0.782
Human Mouse
ameboidal type cell migration GO:0001667 128 0.778
Mouse Fly
neuron projection extension GO:1990138 64 0.777
endocardium development GO:0003157 10 0.771
Mouse
cartilage development GO:0051216 140 0.768
positive regulation of chemotaxis GO:0050921 38 0.768
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.754
face development GO:0060324 38 0.730
Mouse
salivary gland morphogenesis GO:0007435 33 0.727
Fly
cell migration involved in coronary angiogenesis GO:0060981 1 0.724
epithelial cell differentiation involved in kidney development GO:0035850 23 0.721
glomerulus vasculature development GO:0072012 14 0.715
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.715
cell matrix adhesion GO:0007160 68 0.709
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.706
epithelium migration GO:0090132 63 0.705
Mouse Fly
nephron development GO:0072006 109 0.703
artery development GO:0060840 53 0.702
heart morphogenesis GO:0003007 178 0.699
positive regulation of retinal ganglion cell axon guidance GO:1902336 2 0.684
amine metabolic process GO:0009308 45 0.683
positive regulation of glomerular filtration GO:0003104 1 0.683
anatomical structure homeostasis GO:0060249 145 0.681
regulation of smooth muscle cell migration GO:0014910 6 0.678
positive regulation of endothelial cell proliferation GO:0001938 17 0.678
coronary vasculature development GO:0060976 12 0.676
removal of superoxide radicals GO:0019430 12 0.673
rhythmic process GO:0048511 174 0.670
Mouse
melanocyte migration GO:0097324 2 0.663
Mouse
mitotic cell cycle process GO:1903047 159 0.658
chemotaxis GO:0006935 247 0.656
g protein coupled receptor signaling pathway GO:0007186 243 0.654
respiratory tube development GO:0030323 167 0.652
Mouse
axon guidance GO:0007411 141 0.650
metanephric glomerular epithelium development GO:0072244 3 0.650
regulation of cell adhesion GO:0030155 154 0.648
glomerular mesangial cell proliferation GO:0072110 3 0.645
single organism cell adhesion GO:0098602 156 0.632
Mouse
renal system development GO:0072001 225 0.631
post embryonic organ development GO:0048569 17 0.627
Fly
substrate dependent cell migration cell extension GO:0006930 4 0.619
positive regulation of mitotic cell cycle embryonic GO:0045977 2 0.615
actin cytoskeleton organization GO:0030036 220 0.610
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.609
extracellular matrix organization GO:0030198 147 0.608
Mouse
molting cycle GO:0042303 90 0.600
muscle contraction GO:0006936 101 0.596
regulation of cell motility GO:2000145 236 0.594
positive regulation of cell development GO:0010720 237 0.593
positive regulation of cell motility GO:2000147 116 0.587
protein o linked glycosylation GO:0006493 16 0.586
kidney morphogenesis GO:0060993 83 0.585
Rat
elastic fiber assembly GO:0048251 4 0.582
myeloid leukocyte migration GO:0097529 57 0.578
regulation of endothelial cell proliferation GO:0001936 23 0.577
ion transmembrane transport GO:0034220 361 0.575
regulation of bmp signaling pathway GO:0030510 60 0.574
Mouse
peptidyl amino acid modification GO:0018193 336 0.574
gland development GO:0048732 330 0.563
regulation of chemotaxis GO:0050920 53 0.561
regulation of epithelial cell proliferation GO:0050678 141 0.560
Mouse
coronary vasculature morphogenesis GO:0060977 9 0.557
negative regulation of cell adhesion GO:0007162 45 0.555
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.554
chondrocyte differentiation GO:0002062 72 0.553
cardiac cell development GO:0055006 41 0.551
macromolecule glycosylation GO:0043413 55 0.547
positive regulation of lymphangiogenesis GO:1901492 3 0.546
gastrulation GO:0007369 116 0.542
muscle cell development GO:0055001 133 0.541
bone morphogenesis GO:0060349 78 0.540
regulation of cellular ketone metabolic process GO:0010565 66 0.539
venous blood vessel development GO:0060841 13 0.538
ear development GO:0043583 200 0.534
Rat
paracrine signaling GO:0038001 1 0.530
regulation of retinal ganglion cell axon guidance GO:0090259 2 0.527
renal system process GO:0003014 48 0.527
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.527
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.524
glycolipid metabolic process GO:0006664 25 0.524
Mouse
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.518
regulation of glomerular filtration GO:0003093 3 0.515
respiratory system development GO:0060541 190 0.513
Mouse
mitotic cell cycle GO:0000278 195 0.512
learning or memory GO:0007611 148 0.510
regulation of cellular response to growth factor stimulus GO:0090287 82 0.507
regulation of endothelial cell migration GO:0010594 22 0.507
positive regulation of smooth muscle cell migration GO:0014911 4 0.505
ovarian follicle development GO:0001541 40 0.502
Mouse
ovulation cycle GO:0042698 59 0.500
Mouse
regulation of cell projection organization GO:0031344 206 0.497
epithelial tube morphogenesis GO:0060562 303 0.495
Mouse Fly
bmp signaling pathway GO:0030509 93 0.493
Mouse
regulation of stem cell proliferation GO:0072091 78 0.491
Mouse
striated muscle contraction GO:0006941 45 0.491
hair follicle development GO:0001942 85 0.490
extrinsic apoptotic signaling pathway GO:0097191 126 0.489
negative regulation of apoptotic signaling pathway GO:2001234 104 0.489
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.488
divalent inorganic cation transport GO:0072511 178 0.487
cellular response to erythropoietin GO:0036018 1 0.483
Mouse
muscle system process GO:0003012 141 0.482
regulation of cell shape GO:0008360 39 0.475
Mouse Fly
appendage morphogenesis GO:0035107 149 0.474
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.473
Mouse
embryonic hemopoiesis GO:0035162 23 0.467
Mouse Fly
positive regulation of neuron projection development GO:0010976 79 0.462
negative regulation of endothelial cell migration GO:0010596 4 0.459
positive regulation of endothelial cell migration GO:0010595 12 0.457
cell chemotaxis GO:0060326 81 0.457
erk1 and erk2 cascade GO:0070371 77 0.454
retina development in camera type eye GO:0060041 119 0.450
axonogenesis GO:0007409 274 0.450
negative regulation of cell proliferation GO:0008285 296 0.445
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.443
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.441
regulation of neuron projection development GO:0010975 169 0.440
regulation of actin filament based process GO:0032970 99 0.433
glomerular mesangium development GO:0072109 5 0.433
tissue homeostasis GO:0001894 115 0.432
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.432
Mouse
multicellular organismal homeostasis GO:0048871 164 0.430
positive regulation of protein modification process GO:0031401 299 0.429
face morphogenesis GO:0060325 29 0.427
Mouse
stem cell differentiation GO:0048863 268 0.423
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.423
regulation of endothelial cell differentiation GO:0045601 10 0.423
Mouse
regulation of axon extension GO:0030516 43 0.423
metanephric glomerulus vasculature development GO:0072239 7 0.420
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.420
hair cycle GO:0042633 90 0.411
regulation of branching involved in salivary gland morphogenesis by epithelial mesenchymal signaling GO:0060683 1 0.410
mesenchyme development GO:0060485 152 0.407
Rat
ossification GO:0001503 216 0.406
endocardial cell differentiation GO:0060956 4 0.404
developmental growth involved in morphogenesis GO:0060560 138 0.400
regulation of cell projection assembly GO:0060491 38 0.398
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.395
regulation of ras protein signal transduction GO:0046578 114 0.395
odontogenesis GO:0042476 78 0.393
Mouse
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.391
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.391
cellular response to superoxide GO:0071451 14 0.391
blood circulation GO:0008015 195 0.391
liver development GO:0001889 66 0.389
positive regulation of mapk cascade GO:0043410 170 0.387
lymph vessel morphogenesis GO:0036303 11 0.387
Mouse
circulatory system process GO:0003013 197 0.386
epidermis development GO:0008544 187 0.385
cell migration involved in heart development GO:0060973 8 0.383
angiogenesis GO:0001525 201 0.381
response to radiation GO:0009314 165 0.378
Mouse
endothelial cell differentiation GO:0045446 41 0.378
Mouse
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.375
cell junction organization GO:0034330 77 0.372
negative regulation of ras protein signal transduction GO:0046580 18 0.371
muscle cell differentiation GO:0042692 261 0.371
mesenchymal cell differentiation GO:0048762 107 0.370
positive regulation of cell substrate adhesion GO:0010811 47 0.370
vascular smooth muscle cell differentiation GO:0035886 11 0.369
filopodium assembly GO:0046847 19 0.368
nephron tubule morphogenesis GO:0072078 68 0.368
growth plate cartilage development GO:0003417 14 0.368
metanephric nephron development GO:0072210 34 0.368
protein autophosphorylation GO:0046777 61 0.367
formation of primary germ layer GO:0001704 77 0.364
blood coagulation GO:0007596 76 0.362
regulation of organelle organization GO:0033043 289 0.358
cardiac vascular smooth muscle cell development GO:0060948 3 0.357
bone resorption GO:0045453 38 0.349
positive regulation of cell projection organization GO:0031346 95 0.345
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.344
mesangial cell development GO:0072143 4 0.343
neuron migration GO:0001764 122 0.341
regulation of protein autophosphorylation GO:0031952 8 0.341
positive regulation of neuron differentiation GO:0045666 141 0.340
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.340
leukocyte migration GO:0050900 124 0.339
hematopoietic progenitor cell differentiation GO:0002244 143 0.338
Mouse
leukocyte chemotaxis GO:0030595 69 0.335
muscle cell proliferation GO:0033002 52 0.334
melanocyte adhesion GO:0097326 1 0.332
Mouse
organelle fission GO:0048285 170 0.331
response to erythropoietin GO:0036017 1 0.330
Mouse
morphogenesis of an epithelial sheet GO:0002011 27 0.330
organophosphate biosynthetic process GO:0090407 122 0.328
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.326
Mouse
glomerulus morphogenesis GO:0072102 10 0.322
glomerulus vasculature morphogenesis GO:0072103 6 0.322
apoptotic signaling pathway GO:0097190 306 0.320
superoxide metabolic process GO:0006801 27 0.320
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.319
lung alveolus development GO:0048286 45 0.319
Mouse
placenta blood vessel development GO:0060674 31 0.316
positive regulation of bone remodeling GO:0046852 13 0.316
regulation of phospholipid biosynthetic process GO:0071071 3 0.311
positive regulation of axon guidance GO:1902669 5 0.310
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.308
regulation of bone remodeling GO:0046850 28 0.305
sensory perception GO:0007600 245 0.303
Mouse
negative regulation of nervous system development GO:0051961 156 0.303
liposaccharide metabolic process GO:1903509 27 0.302
Mouse
ras protein signal transduction GO:0007265 77 0.301
sensory perception of chemical stimulus GO:0007606 51 0.299
cardiac chamber morphogenesis GO:0003206 93 0.299
phosphatidylinositol mediated signaling GO:0048015 41 0.295
carbohydrate derivative biosynthetic process GO:1901137 183 0.293
Rat
regulation of cellular amino acid metabolic process GO:0006521 5 0.293
vasodilation GO:0042311 28 0.293
sphingolipid metabolic process GO:0006665 45 0.291
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.291
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.289
bone development GO:0060348 120 0.288
labyrinthine layer development GO:0060711 49 0.288
negative regulation of cell development GO:0010721 169 0.288
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.284
regulation of phospholipase a2 activity GO:0032429 3 0.284
positive regulation of protein autophosphorylation GO:0031954 4 0.284
embryonic heart tube morphogenesis GO:0003143 51 0.284
stem cell development GO:0048864 219 0.280
morphogenesis of a branching epithelium GO:0061138 193 0.280
Mouse
regulation of cellular response to stress GO:0080135 159 0.279
positive regulation of organelle organization GO:0010638 128 0.279
regulation of branching involved in salivary gland morphogenesis GO:0060693 11 0.277
regulation of cellular component size GO:0032535 121 0.274
positive regulation of membrane potential GO:0045838 15 0.273
developmental cell growth GO:0048588 84 0.272
regulation of tissue remodeling GO:0034103 38 0.271
Mouse
ear morphogenesis GO:0042471 118 0.269
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.267
wound healing GO:0042060 157 0.266
Mouse Rat
morphogenesis of embryonic epithelium GO:0016331 159 0.265
positive regulation of creb transcription factor activity GO:0032793 4 0.263
myeloid leukocyte differentiation GO:0002573 119 0.263
Mouse
nephron morphogenesis GO:0072028 69 0.263
Rat
regulation of muscle tissue development GO:1901861 97 0.262
skin development GO:0043588 220 0.262
regulation of response to reactive oxygen species GO:1901031 9 0.261
smooth muscle cell chemotaxis GO:0071670 2 0.261
regulation of epithelial cell migration GO:0010632 35 0.259
regulation of transmembrane transport GO:0034762 128 0.259
cardiac muscle tissue morphogenesis GO:0055008 44 0.255
morphogenesis of a branching structure GO:0001763 203 0.253
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.252
regulation of blood pressure GO:0008217 93 0.250
tripeptide transport GO:0042939 1 0.250
cellular ketone metabolic process GO:0042180 84 0.250
hemostasis GO:0007599 78 0.248
heart trabecula morphogenesis GO:0061384 26 0.245
stem cell maintenance GO:0019827 130 0.244
regulation of lymphangiogenesis GO:1901490 3 0.244
negative regulation of chondrocyte differentiation GO:0032331 13 0.244
phospholipid metabolic process GO:0006644 87 0.243
Human Mouse
small gtpase mediated signal transduction GO:0007264 97 0.243
membrane lipid metabolic process GO:0006643 53 0.242
Mouse
placenta development GO:0001890 140 0.242
inositol lipid mediated signaling GO:0048017 41 0.242
cell proliferation involved in metanephros development GO:0072203 9 0.241
positive regulation of epithelial cell proliferation GO:0050679 68 0.239
Mouse
dna biosynthetic process GO:0071897 22 0.239
eye photoreceptor cell development GO:0042462 31 0.239
glomerular epithelium development GO:0072010 11 0.238
tissue remodeling GO:0048771 102 0.238
Mouse
positive regulation of map kinase activity GO:0043406 84 0.237
positive regulation of hydrolase activity GO:0051345 148 0.237
Human
cardiac right ventricle formation GO:0003219 3 0.236
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.236
coronary vein morphogenesis GO:0003169 2 0.235
response to superoxide GO:0000303 16 0.235
positive regulation of proteolysis GO:0045862 85 0.235
lamellipodium organization GO:0097581 29 0.233
Mouse
cell differentiation involved in kidney development GO:0061005 33 0.232
positive regulation of growth GO:0045927 104 0.231
developmental maturation GO:0021700 193 0.230
Mouse
vascular smooth muscle cell development GO:0097084 7 0.229
cardiac endothelial cell differentiation GO:0003348 4 0.227
response to oxygen radical GO:0000305 16 0.227
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.226
leukocyte cell cell adhesion GO:0007159 14 0.224
positive regulation of behavior GO:0048520 40 0.223
cardiac right atrium morphogenesis GO:0003213 3 0.222
positive regulation of lipid metabolic process GO:0045834 40 0.221
Human
extracellular matrix assembly GO:0085029 12 0.220
pro t cell differentiation GO:0002572 3 0.219
Mouse
renal system process involved in regulation of blood volume GO:0001977 4 0.219
granulocyte chemotaxis GO:0071621 39 0.218
cardiac chamber development GO:0003205 108 0.218
regulation of blood coagulation GO:0030193 28 0.216
renal tubule development GO:0061326 87 0.216
Fly
regionalization GO:0003002 337 0.216
striated muscle cell development GO:0055002 125 0.213
cell differentiation involved in metanephros development GO:0072202 12 0.213
epithelial cell development GO:0002064 159 0.212
Fly
positive regulation of dna biosynthetic process GO:2000573 4 0.208
nephron tubule development GO:0072080 84 0.206
renal system vasculature morphogenesis GO:0061438 7 0.205
positive regulation of bmp signaling pathway GO:0030513 23 0.204
Mouse
cardiac septum morphogenesis GO:0060411 46 0.203
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.202
cellular response to stem cell factor stimulus GO:0036216 3 0.202
Mouse
gliogenesis GO:0042063 141 0.202
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.202
glomerular endothelium development GO:0072011 2 0.200
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.200
cardiac muscle cell proliferation GO:0060038 31 0.200
body morphogenesis GO:0010171 45 0.199
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.199
regulation of cell cycle process GO:0010564 160 0.197
positive regulation of neural precursor cell proliferation GO:2000179 42 0.197
positive regulation of cellular amine metabolic process GO:0033240 5 0.196
inner ear morphogenesis GO:0042472 101 0.191
glycosylation GO:0070085 62 0.190
regulation of neuron differentiation GO:0045664 281 0.189
cell growth GO:0016049 130 0.189
regulation of endothelial cell chemotaxis GO:2001026 1 0.189
retinal ganglion cell axon guidance GO:0031290 18 0.189
calcium ion transport GO:0006816 159 0.189
telencephalon cell migration GO:0022029 55 0.188
platelet activation GO:0030168 40 0.188
protein import into nucleus GO:0006606 95 0.186
multi multicellular organism process GO:0044706 109 0.185
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.185
organ growth GO:0035265 117 0.184
regulation of map kinase activity GO:0043405 120 0.184
dna metabolic process GO:0006259 303 0.183
muscle cell migration GO:0014812 19 0.183
negative regulation of intracellular signal transduction GO:1902532 167 0.182
endothelium development GO:0003158 45 0.181
Mouse
photoreceptor cell differentiation GO:0046530 52 0.180
neuron projection guidance GO:0097485 141 0.180
developmental programmed cell death GO:0010623 41 0.180
Mouse
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.178
macromolecule catabolic process GO:0009057 281 0.178
endocardial cushion formation GO:0003272 13 0.178
cellular amine metabolic process GO:0044106 44 0.178
positive regulation of cell death GO:0010942 224 0.175
positive regulation of presynaptic membrane organization GO:1901631 1 0.175
response to fibroblast growth factor GO:0071774 47 0.174
regulation of lipid kinase activity GO:0043550 14 0.174
Human
cellular lipid metabolic process GO:0044255 323 0.173
Human Mouse
commissural neuron axon guidance GO:0071679 8 0.172
response to thyroid hormone GO:0097066 2 0.171
Mouse
chemical homeostasis within a tissue GO:0048875 9 0.169
Mouse
ureteric bud development GO:0001657 94 0.169
regulation of organ morphogenesis GO:2000027 144 0.168
myofibril assembly GO:0030239 34 0.167
regulation of stem cell differentiation GO:2000736 50 0.166
regulation of blood vessel endothelial cell migration GO:0043535 12 0.166
regulation of cardiac cell fate specification GO:2000043 1 0.166
glycerolipid metabolic process GO:0046486 122 0.164
Human Mouse
regulation of protein kinase b signaling GO:0051896 56 0.164
metanephric glomerulus development GO:0072224 13 0.164
cerebral cortex cell migration GO:0021795 44 0.162
regulation of fibroblast proliferation GO:0048145 34 0.161
determination of heart left right asymmetry GO:0061371 48 0.160
cardiac muscle cell differentiation GO:0055007 69 0.160
bile acid secretion GO:0032782 2 0.159
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.158
ceramide metabolic process GO:0006672 31 0.157
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.154
Mouse
glomerular epithelial cell differentiation GO:0072311 10 0.154
regulation of transferase activity GO:0051338 263 0.154
transmembrane transport GO:0055085 412 0.153
protein catabolic process GO:0030163 221 0.150
cardiac ventricle development GO:0003231 83 0.150
embryonic skeletal system development GO:0048706 120 0.149
Mouse
myeloid cell differentiation GO:0030099 233 0.149
Mouse
regulation of hormone levels GO:0010817 211 0.149
Mouse
endochondral bone morphogenesis GO:0060350 50 0.149
regulation of protein targeting GO:1903533 61 0.148
positive regulation of nuclear division GO:0051785 27 0.148
regulation of wound healing GO:0061041 40 0.146
regulation of extent of cell growth GO:0061387 52 0.146
glomerular capillary formation GO:0072104 6 0.145
mechanoreceptor differentiation GO:0042490 67 0.144
somitogenesis GO:0001756 69 0.144
cartilage condensation GO:0001502 18 0.143
peptidyl tyrosine autophosphorylation GO:0038083 5 0.142
Mouse
regulation of biomineral tissue development GO:0070167 33 0.142
embryonic heart tube development GO:0035050 65 0.141
erythropoietin mediated signaling pathway GO:0038162 1 0.141
Mouse
ventricular septum morphogenesis GO:0060412 27 0.140
lateral inhibition GO:0046331 1 0.137
carbohydrate metabolic process GO:0005975 230 0.136
mesonephros development GO:0001823 97 0.136
negative regulation of sodium proton antiporter activity GO:0032416 1 0.136
kidney vasculature morphogenesis GO:0061439 7 0.134
plasma membrane organization GO:0007009 90 0.133
kidney interstitial fibroblast differentiation GO:0072071 5 0.133
positive regulation of neuroblast proliferation GO:0002052 19 0.133
nucleotide biosynthetic process GO:0009165 78 0.132
protein glycosylation GO:0006486 55 0.132
epithelial mesenchymal cell signaling GO:0060684 7 0.131
response to amino acid GO:0043200 37 0.130
Mouse
second messenger mediated signaling GO:0019932 73 0.130
regulation of blood vessel remodeling GO:0060312 3 0.129
Mouse
positive regulation of epithelial cell migration GO:0010634 19 0.128
regulation of phospholipase c activity GO:1900274 3 0.128
Human
aorta development GO:0035904 23 0.128
axon extension involved in axon guidance GO:0048846 14 0.128
nucleotide metabolic process GO:0009117 332 0.127
synapse organization GO:0050808 125 0.127
development of primary female sexual characteristics GO:0046545 73 0.127
Mouse
kidney epithelium development GO:0072073 121 0.127
regulation of cellular amine metabolic process GO:0033238 20 0.126
membrane organization GO:0061024 245 0.126
positive regulation of protein kinase b signaling GO:0051897 32 0.125
cell substrate junction assembly GO:0007044 24 0.125
regulation of hemostasis GO:1900046 28 0.125
renal interstitial fibroblast development GO:0072141 5 0.124
negative regulation of molecular function GO:0044092 258 0.124
hormone secretion GO:0046879 128 0.123
endoderm development GO:0007492 45 0.123
positive regulation of transferase activity GO:0051347 167 0.122
hindbrain radial glia guided cell migration GO:0021932 12 0.121
regulation of cytoskeleton organization GO:0051493 122 0.120

Pdgfrb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
hepatobiliary disease DOID:3118 0 0.153
disease of anatomical entity DOID:7 0 0.153
gastrointestinal system disease DOID:77 0 0.153
liver disease DOID:409 0 0.153
immune system disease DOID:2914 0 0.144