Mus musculus

0 known processes

Pdk3

pyruvate dehydrogenase kinase, isoenzyme 3

(Aliases: 2610001M10Rik,AI035637,MGC6383)

Pdk3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular catabolic process GO:0031329 242 0.104
nucleotide metabolic process GO:0009117 332 0.091
cellular nitrogen compound catabolic process GO:0044270 280 0.078
negative regulation of cellular protein metabolic process GO:0032269 247 0.077
nucleoside phosphate metabolic process GO:0006753 338 0.074
organic cyclic compound catabolic process GO:1901361 295 0.074
nucleobase containing small molecule metabolic process GO:0055086 352 0.072
ribose phosphate metabolic process GO:0019693 291 0.064
cellular amino acid metabolic process GO:0006520 103 0.059
negative regulation of protein metabolic process GO:0051248 282 0.059
regulation of purine nucleotide catabolic process GO:0033121 122 0.059
heterocycle catabolic process GO:0046700 280 0.058
carbohydrate metabolic process GO:0005975 230 0.056
Human
positive regulation of cellular catabolic process GO:0031331 148 0.054
aromatic compound catabolic process GO:0019439 286 0.053
oxidation reduction process GO:0055114 342 0.049
small gtpase mediated signal transduction GO:0007264 97 0.049
organonitrogen compound catabolic process GO:1901565 264 0.048
intracellular protein transport GO:0006886 204 0.047
purine nucleotide metabolic process GO:0006163 302 0.046
glycosyl compound metabolic process GO:1901657 246 0.046
ribonucleotide metabolic process GO:0009259 291 0.045
regulation of organelle organization GO:0033043 289 0.045
ion transmembrane transport GO:0034220 361 0.045
positive regulation of nucleotide catabolic process GO:0030813 88 0.042
glycosyl compound catabolic process GO:1901658 206 0.042
ribonucleoside metabolic process GO:0009119 245 0.041
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
nitrogen compound transport GO:0071705 271 0.041
nucleoside metabolic process GO:0009116 246 0.041
ribonucleoside catabolic process GO:0042454 206 0.040
purine containing compound catabolic process GO:0072523 213 0.040
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.040
nucleotide catabolic process GO:0009166 217 0.040
regulation of hydrolase activity GO:0051336 246 0.039
nucleoside catabolic process GO:0009164 206 0.039
purine containing compound metabolic process GO:0072521 311 0.039
cation transport GO:0006812 399 0.039
carbohydrate derivative catabolic process GO:1901136 231 0.038
organophosphate catabolic process GO:0046434 232 0.037
cellular ketone metabolic process GO:0042180 84 0.037
Human Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.037
negative regulation of molecular function GO:0044092 258 0.037
cellular macromolecule catabolic process GO:0044265 206 0.036
amine metabolic process GO:0009308 45 0.036
nadph regeneration GO:0006740 2 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
cellular amine metabolic process GO:0044106 44 0.035
purine ribonucleoside metabolic process GO:0046128 241 0.035
purine nucleoside catabolic process GO:0006152 205 0.034
purine ribonucleotide catabolic process GO:0009154 208 0.034
ras protein signal transduction GO:0007265 77 0.034
negative regulation of protein modification process GO:0031400 163 0.034
spermatogenesis GO:0007283 284 0.034
microtubule cytoskeleton organization GO:0000226 157 0.033
monocarboxylic acid metabolic process GO:0032787 191 0.033
Human Mouse
cytoplasmic transport GO:0016482 234 0.033
carbohydrate derivative biosynthetic process GO:1901137 183 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
peptide transport GO:0015833 133 0.032
purine nucleoside metabolic process GO:0042278 241 0.032
regulation of purine nucleotide metabolic process GO:1900542 169 0.032
apoptotic signaling pathway GO:0097190 306 0.032
transmembrane transport GO:0055085 412 0.031
response to oxidative stress GO:0006979 123 0.031
purine ribonucleoside catabolic process GO:0046130 205 0.031
negative regulation of phosphate metabolic process GO:0045936 184 0.030
protein targeting GO:0006605 143 0.030
homeostasis of number of cells GO:0048872 210 0.030
negative regulation of phosphorus metabolic process GO:0010563 184 0.030
mitotic cell cycle process GO:1903047 159 0.030
positive regulation of hydrolase activity GO:0051345 148 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.029
Human Mouse
macromolecule catabolic process GO:0009057 281 0.029
mitotic cytokinesis GO:0000281 4 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
organophosphate biosynthetic process GO:0090407 122 0.028
positive regulation of organelle organization GO:0010638 128 0.028
coenzyme metabolic process GO:0006732 52 0.027
Human Mouse
organelle fission GO:0048285 170 0.027
regulation of cell cycle process GO:0010564 160 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
inorganic ion transmembrane transport GO:0098660 234 0.026
cellular lipid metabolic process GO:0044255 323 0.026
Human Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
positive regulation of nucleoside metabolic process GO:0045979 91 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
regulation of hormone levels GO:0010817 211 0.025
sulfur compound metabolic process GO:0006790 100 0.025
Human Mouse
cytokinetic process GO:0032506 2 0.025
positive regulation of gtpase activity GO:0043547 85 0.024
protein catabolic process GO:0030163 221 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
cellular response to lipid GO:0071396 145 0.024
Human
regulation of gtp catabolic process GO:0033124 113 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
positive regulation of cell cycle GO:0045787 92 0.024
regulation of cytoskeleton organization GO:0051493 122 0.024
small molecule biosynthetic process GO:0044283 132 0.024
maintenance of location GO:0051235 89 0.023
cation transmembrane transport GO:0098655 266 0.023
cofactor metabolic process GO:0051186 80 0.023
Human Mouse
cellular response to dna damage stimulus GO:0006974 207 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
regulation of mitotic cell cycle GO:0007346 126 0.023
anion transport GO:0006820 177 0.023
protein complex disassembly GO:0043241 40 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
positive regulation of protein modification process GO:0031401 299 0.023
protein localization to organelle GO:0033365 185 0.023
membrane organization GO:0061024 245 0.023
wnt signaling pathway GO:0016055 188 0.023
meiotic cell cycle GO:0051321 122 0.022
lipid biosynthetic process GO:0008610 179 0.022
cellular protein catabolic process GO:0044257 155 0.022
mitotic cell cycle GO:0000278 195 0.022
retrograde transport endosome to golgi GO:0042147 2 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
cellular chemical homeostasis GO:0055082 215 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
nuclear import GO:0051170 95 0.021
pyridine nucleotide biosynthetic process GO:0019363 4 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
dna replication independent nucleosome assembly GO:0006336 1 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
microtubule based process GO:0007017 236 0.020
regulation of protein transport GO:0051223 163 0.020
peptidyl amino acid modification GO:0018193 336 0.020
Human
cell type specific apoptotic process GO:0097285 268 0.020
protein localization to nucleus GO:0034504 121 0.020
positive regulation of gtp catabolic process GO:0033126 85 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.019
regulation of intracellular protein transport GO:0033157 82 0.019
regulation of cell cycle GO:0051726 281 0.019
cellular homeostasis GO:0019725 240 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
nuclear division GO:0000280 158 0.019
muscle cell differentiation GO:0042692 261 0.019
regulation of kinase activity GO:0043549 249 0.019
oocyte construction GO:0007308 2 0.018
protein maturation GO:0051604 176 0.018
amide transport GO:0042886 138 0.018
establishment of protein localization to organelle GO:0072594 118 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
glucose metabolic process GO:0006006 92 0.018
Human
protein import GO:0017038 101 0.018
organelle assembly GO:0070925 177 0.018
regulation of transferase activity GO:0051338 263 0.018
peptide hormone secretion GO:0030072 109 0.018
regulation of protein localization GO:0032880 231 0.018
nuclear transport GO:0051169 139 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
guanosine containing compound metabolic process GO:1901068 144 0.017
camera type eye development GO:0043010 266 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
compound eye development GO:0048749 1 0.017
response to inorganic substance GO:0010035 96 0.017
regulation of microtubule based process GO:0032886 52 0.017
asymmetric stem cell division GO:0098722 3 0.017
negative regulation of cell cycle process GO:0010948 69 0.017
striated muscle tissue development GO:0014706 293 0.017
germ cell development GO:0007281 185 0.017
glucose catabolic process GO:0006007 3 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
carbohydrate homeostasis GO:0033500 128 0.017
mrna metabolic process GO:0016071 84 0.017
male gamete generation GO:0048232 285 0.016
regulation of cell projection organization GO:0031344 206 0.016
regulation of mapk cascade GO:0043408 248 0.016
protein import into nucleus GO:0006606 95 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
mapk cascade GO:0000165 281 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
cell adhesion GO:0007155 329 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
meiosis i GO:0007127 60 0.016
sensory perception GO:0007600 245 0.016
development of primary sexual characteristics GO:0045137 143 0.016
negative regulation of organelle organization GO:0010639 90 0.016
hormone secretion GO:0046879 128 0.015
dephosphorylation GO:0016311 129 0.015
regulation of secretion by cell GO:1903530 249 0.015
glucose homeostasis GO:0042593 128 0.015
nicotinamide nucleotide biosynthetic process GO:0019359 4 0.015
regulation of secretion GO:0051046 274 0.015
positive regulation of cell cycle process GO:0090068 61 0.015
sensory organ morphogenesis GO:0090596 242 0.015
endocytosis GO:0006897 168 0.015
monosaccharide metabolic process GO:0005996 106 0.015
Human
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of cellular response to stress GO:0080135 159 0.015
response to organonitrogen compound GO:0010243 246 0.015
protein ubiquitination GO:0016567 171 0.015
lymphocyte differentiation GO:0030098 242 0.015
regulation of intracellular transport GO:0032386 159 0.015
substantia nigra development GO:0021762 2 0.015
positive regulation of cell death GO:0010942 224 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
protein processing GO:0016485 163 0.014
regulation of anatomical structure size GO:0090066 178 0.014
membrane lipid biosynthetic process GO:0046467 32 0.014
hexose catabolic process GO:0019320 3 0.014
rho protein signal transduction GO:0007266 32 0.014
insulin secretion GO:0030073 89 0.014
neuron death GO:0070997 154 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
cilium assembly GO:0042384 81 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
lymphocyte proliferation GO:0046651 164 0.014
peptide secretion GO:0002790 114 0.014
regulation of system process GO:0044057 200 0.014
asymmetric neuroblast division GO:0055059 1 0.014
gtp metabolic process GO:0046039 144 0.014
skeletal muscle organ development GO:0060538 163 0.014
gland development GO:0048732 330 0.014
canonical wnt signaling pathway GO:0060070 130 0.013
pentose phosphate shunt GO:0006098 2 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
regulation of centriole replication GO:0046599 1 0.013
response to oxygen levels GO:0070482 62 0.013
Human
rac protein signal transduction GO:0016601 13 0.013
regulation of homeostatic process GO:0032844 182 0.013
cellular response to oxidative stress GO:0034599 76 0.013
actin cytoskeleton organization GO:0030036 220 0.013
blood circulation GO:0008015 195 0.013
ameboidal type cell migration GO:0001667 128 0.013
cellular ion homeostasis GO:0006873 165 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
skin development GO:0043588 220 0.013
muscle tissue development GO:0060537 308 0.013
positive regulation of mitotic cell cycle GO:0045931 41 0.013
cellular protein complex assembly GO:0043623 116 0.013
regulation of neuron death GO:1901214 134 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
skeletal system development GO:0001501 356 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
response to radiation GO:0009314 165 0.013
apoptotic mitochondrial changes GO:0008637 48 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
myeloid cell differentiation GO:0030099 233 0.013
organic acid transport GO:0015849 101 0.012
extracellular structure organization GO:0043062 148 0.012
regulation of protein catabolic process GO:0042176 108 0.012
epidermis development GO:0008544 187 0.012
fertilization GO:0009566 127 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
hexose metabolic process GO:0019318 98 0.012
Human
engulfment of apoptotic cell GO:0043652 3 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
cytokine production GO:0001816 319 0.012
erythrocyte differentiation GO:0030218 88 0.012
regulation of cell activation GO:0050865 289 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
digestive system development GO:0055123 200 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
regulation of protein maturation GO:1903317 96 0.012
fatty acid metabolic process GO:0006631 121 0.012
Human Mouse
microtubule based movement GO:0007018 84 0.012
neural precursor cell proliferation GO:0061351 121 0.012
alcohol metabolic process GO:0006066 116 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
intra golgi vesicle mediated transport GO:0006891 1 0.012
protein depolymerization GO:0051261 34 0.012
regulation of membrane potential GO:0042391 192 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
protein secretion GO:0009306 111 0.011
extracellular matrix organization GO:0030198 147 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
meiotic cell cycle process GO:1903046 77 0.011
response to organic cyclic compound GO:0014070 198 0.011
chemotaxis GO:0006935 247 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
t cell activation GO:0042110 289 0.011
positive regulation of secretion GO:0051047 130 0.011
neuron apoptotic process GO:0051402 142 0.011
myeloid cell homeostasis GO:0002262 114 0.011
negative regulation of cell development GO:0010721 169 0.011
gonad development GO:0008406 141 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
endomembrane system organization GO:0010256 147 0.011
regulation of microtubule cytoskeleton organization GO:0070507 37 0.011
developmental maturation GO:0021700 193 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
chromatin organization GO:0006325 206 0.011
regulation of actin filament based process GO:0032970 99 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.011
divalent metal ion transport GO:0070838 172 0.011
circulatory system process GO:0003013 197 0.011
sequestering of calcium ion GO:0051208 18 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
synapsis GO:0007129 34 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
regulation of protein kinase activity GO:0045859 232 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
positive regulation of kinase activity GO:0033674 155 0.011
cellular protein complex disassembly GO:0043624 36 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
response to acid chemical GO:0001101 111 0.011
Human
regulation of multi organism process GO:0043900 111 0.011
positive regulation of protein transport GO:0051222 93 0.011
spindle assembly involved in mitosis GO:0090307 4 0.010
transmission of nerve impulse GO:0019226 76 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
centromere complex assembly GO:0034508 3 0.010
positive regulation of cell development GO:0010720 237 0.010
regulation of mitotic cell cycle phase transition GO:1901990 73 0.010
response to light stimulus GO:0009416 135 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
Human
oxidoreduction coenzyme metabolic process GO:0006733 16 0.010
divalent inorganic cation transport GO:0072511 178 0.010
chromosome organization involved in meiosis GO:0070192 39 0.010
negative regulation of wnt signaling pathway GO:0030178 73 0.010
regulation of ossification GO:0030278 112 0.010
muscle system process GO:0003012 141 0.010
regulation of cytokine production GO:0001817 266 0.010
nicotinamide nucleotide metabolic process GO:0046496 12 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
positive regulation of secretion by cell GO:1903532 114 0.010
regulation of cell division GO:0051302 76 0.010
sequestering of metal ion GO:0051238 19 0.010
organism emergence from protective structure GO:0071684 4 0.010
leukocyte proliferation GO:0070661 172 0.010
positive regulation of nervous system development GO:0051962 221 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
fat cell differentiation GO:0045444 160 0.010

Pdk3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011
sensory system disease DOID:0050155 0 0.011
immune system disease DOID:2914 0 0.010