Mus musculus

25 known processes

Pdlim3

PDZ and LIM domain 3

(Aliases: AI463105,ALP,Actn2lp)

Pdlim3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle cell development GO:0055001 133 0.641
Mouse Fly
muscle system process GO:0003012 141 0.622
cardiac muscle cell development GO:0055013 39 0.599
cellular component assembly involved in morphogenesis GO:0010927 139 0.565
Mouse Fly
muscle tissue development GO:0060537 308 0.527
striated muscle tissue development GO:0014706 293 0.512
striated muscle cell development GO:0055002 125 0.492
Mouse Fly
actin filament based movement GO:0030048 23 0.459
muscle contraction GO:0006936 101 0.450
muscle cell differentiation GO:0042692 261 0.445
Mouse Fly
regulation of system process GO:0044057 200 0.434
sarcomere organization GO:0045214 24 0.390
Mouse
organelle assembly GO:0070925 177 0.389
Mouse Fly
muscle fiber development GO:0048747 76 0.386
actin cytoskeleton organization GO:0030036 220 0.347
cardiac muscle tissue development GO:0048738 130 0.346
skeletal muscle organ development GO:0060538 163 0.312
cardiac muscle cell differentiation GO:0055007 69 0.301
regulation of muscle system process GO:0090257 80 0.271
skeletal myofibril assembly GO:0014866 4 0.237
circulatory system process GO:0003013 197 0.235
striated muscle myosin thick filament assembly GO:0071688 1 0.226
heart morphogenesis GO:0003007 178 0.224
actin filament organization GO:0007015 113 0.217
cell adhesion GO:0007155 329 0.197
Fly
myosin filament organization GO:0031033 3 0.190
skeletal muscle thin filament assembly GO:0030240 2 0.186
heart contraction GO:0060047 93 0.184
heart process GO:0003015 94 0.173
nucleobase containing small molecule metabolic process GO:0055086 352 0.168
neuromuscular process GO:0050905 99 0.160
cardiac cell development GO:0055006 41 0.158
blood circulation GO:0008015 195 0.158
cardiac chamber development GO:0003205 108 0.156
transmembrane transport GO:0055085 412 0.147
myosin filament assembly GO:0031034 2 0.139
regulation of protein transport GO:0051223 163 0.128
actomyosin structure organization GO:0031032 56 0.126
Mouse Fly
regulation of cell substrate adhesion GO:0010810 73 0.126
Fly
cardiocyte differentiation GO:0035051 87 0.122
regulation of intracellular transport GO:0032386 159 0.118
cytoplasmic transport GO:0016482 234 0.114
skeletal muscle fiber development GO:0048741 58 0.114
cation transport GO:0006812 399 0.105
regulation of hydrolase activity GO:0051336 246 0.101
cardiac muscle contraction GO:0060048 32 0.099
extracellular structure organization GO:0043062 148 0.098
striated muscle contraction GO:0006941 45 0.095
mesenchyme development GO:0060485 152 0.093
negative regulation of molecular function GO:0044092 258 0.093
regulation of cell growth GO:0001558 91 0.090
regulation of skeletal muscle contraction GO:0014819 3 0.089
negative regulation of phosphate metabolic process GO:0045936 184 0.087
regulation of cell migration GO:0030334 219 0.085
ion transmembrane transport GO:0034220 361 0.085
regulation of anatomical structure size GO:0090066 178 0.084
cellular response to growth factor stimulus GO:0071363 197 0.083
cell substrate adhesion GO:0031589 130 0.083
Fly
regulation of proteolysis GO:0030162 164 0.081
positive regulation of nervous system development GO:0051962 221 0.081
regulation of cell motility GO:2000145 236 0.080
response to oxygen levels GO:0070482 62 0.079
divalent inorganic cation transport GO:0072511 178 0.079
muscle adaptation GO:0043500 39 0.078
stem cell development GO:0048864 219 0.077
dna metabolic process GO:0006259 303 0.077
intracellular protein transport GO:0006886 204 0.076
negative regulation of phosphorus metabolic process GO:0010563 184 0.075
extracellular matrix organization GO:0030198 147 0.071
regulation of protein kinase activity GO:0045859 232 0.070
response to growth factor GO:0070848 198 0.067
cellular ion homeostasis GO:0006873 165 0.066
negative regulation of hydrolase activity GO:0051346 71 0.065
actin mediated cell contraction GO:0070252 15 0.065
single organism cell adhesion GO:0098602 156 0.065
negative regulation of potassium ion transmembrane transporter activity GO:1901017 3 0.064
cellular homeostasis GO:0019725 240 0.063
regulation of heart contraction GO:0008016 77 0.063
regulation of muscle contraction GO:0006937 49 0.061
ras protein signal transduction GO:0007265 77 0.061
regulation of cellular ketone metabolic process GO:0010565 66 0.060
regulation of striated muscle contraction GO:0006942 25 0.059
cell growth GO:0016049 130 0.058
gland development GO:0048732 330 0.058
regulation of muscle adaptation GO:0043502 31 0.058
blood vessel morphogenesis GO:0048514 285 0.058
regulation of neuron differentiation GO:0045664 281 0.057
mapk cascade GO:0000165 281 0.056
negative regulation of cellular component organization GO:0051129 194 0.055
muscle hypertrophy GO:0014896 24 0.055
stem cell differentiation GO:0048863 268 0.054
regulation of intracellular protein transport GO:0033157 82 0.054
response to transforming growth factor beta GO:0071559 88 0.054
nucleoside catabolic process GO:0009164 206 0.054
developmental growth involved in morphogenesis GO:0060560 138 0.054
glycosyl compound catabolic process GO:1901658 206 0.053
protein maturation GO:0051604 176 0.053
regulation of transmembrane transport GO:0034762 128 0.053
angiogenesis GO:0001525 201 0.052
cell fate commitment GO:0045165 210 0.052
anatomical structure homeostasis GO:0060249 145 0.051
inorganic cation transmembrane transport GO:0098662 207 0.051
cartilage development GO:0051216 140 0.051
regulation of establishment of protein localization GO:0070201 181 0.050
response to hypoxia GO:0001666 58 0.050
organic cyclic compound catabolic process GO:1901361 295 0.050
cardiac chamber morphogenesis GO:0003206 93 0.050
cellular calcium ion homeostasis GO:0006874 119 0.050
nucleoside phosphate catabolic process GO:1901292 222 0.049
wound healing GO:0042060 157 0.048
peptidyl amino acid modification GO:0018193 336 0.048
cardiac muscle fiber development GO:0048739 4 0.047
regulation of heart rate GO:0002027 36 0.047
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.047
positive regulation of cell development GO:0010720 237 0.047
regulation of cell cycle GO:0051726 281 0.047
maintenance of location GO:0051235 89 0.046
regulation of cysteine type endopeptidase activity GO:2000116 65 0.046
positive regulation of neuron differentiation GO:0045666 141 0.046
positive regulation of protein phosphorylation GO:0001934 242 0.046
inorganic ion transmembrane transport GO:0098660 234 0.046
regulation of endopeptidase activity GO:0052548 89 0.046
second messenger mediated signaling GO:0019932 73 0.046
regulation of feeding behavior GO:0060259 3 0.045
mitotic cell cycle GO:0000278 195 0.044
cellular ketone metabolic process GO:0042180 84 0.044
atp catabolic process GO:0006200 55 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.044
regulation of cytoplasmic transport GO:1903649 112 0.043
elastic fiber assembly GO:0048251 4 0.043
cellular metal ion homeostasis GO:0006875 151 0.042
nucleocytoplasmic transport GO:0006913 139 0.042
regulation of protein localization GO:0032880 231 0.042
epithelial cell development GO:0002064 159 0.042
smooth muscle contraction GO:0006939 44 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.042
macromolecule catabolic process GO:0009057 281 0.041
protein import into nucleus GO:0006606 95 0.041
i kappab kinase nf kappab signaling GO:0007249 85 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
negative regulation of cell proliferation GO:0008285 296 0.040
microtubule based process GO:0007017 236 0.040
regulation of organelle organization GO:0033043 289 0.040
regulation of map kinase activity GO:0043405 120 0.040
regulation of peptidase activity GO:0052547 96 0.039
cardiac muscle tissue morphogenesis GO:0055008 44 0.039
morphogenesis of a branching epithelium GO:0061138 193 0.039
heterocycle catabolic process GO:0046700 280 0.039
regulation of mapk cascade GO:0043408 248 0.039
axonogenesis GO:0007409 274 0.039
metal ion homeostasis GO:0055065 189 0.038
regulation of apoptotic signaling pathway GO:2001233 197 0.038
nucleoside metabolic process GO:0009116 246 0.038
negative regulation of protein processing GO:0010955 79 0.038
purine containing compound catabolic process GO:0072523 213 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
negative regulation of protein metabolic process GO:0051248 282 0.037
skeletal system development GO:0001501 356 0.037
regulation of nucleotide catabolic process GO:0030811 122 0.037
response to inorganic substance GO:0010035 96 0.036
sensory organ morphogenesis GO:0090596 242 0.036
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.036
apoptotic signaling pathway GO:0097190 306 0.036
cell junction organization GO:0034330 77 0.036
establishment of protein localization to organelle GO:0072594 118 0.036
protein import GO:0017038 101 0.036
cation transmembrane transport GO:0098655 266 0.036
lipid localization GO:0010876 126 0.036
muscle tissue morphogenesis GO:0060415 53 0.036
multicellular organismal signaling GO:0035637 91 0.036
regulation of body fluid levels GO:0050878 162 0.035
appendage development GO:0048736 166 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.035
cardiac myofibril assembly GO:0055003 12 0.035
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.035
fatty acid metabolic process GO:0006631 121 0.035
negative regulation of growth GO:0045926 99 0.035
positive regulation of cell adhesion GO:0045785 80 0.035
camera type eye development GO:0043010 266 0.035
positive regulation of protein transport GO:0051222 93 0.035
neuromuscular process controlling balance GO:0050885 59 0.035
positive regulation of cell motility GO:2000147 116 0.034
calcium ion homeostasis GO:0055074 127 0.034
epithelial cell morphogenesis GO:0003382 41 0.034
myotube cell development GO:0014904 60 0.034
purine nucleoside triphosphate metabolic process GO:0009144 226 0.034
cytokine production GO:0001816 319 0.034
branching involved in salivary gland morphogenesis GO:0060445 26 0.034
morphogenesis of a polarized epithelium GO:0001738 37 0.034
nuclear transport GO:0051169 139 0.034
cellular amine metabolic process GO:0044106 44 0.034
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.034
regulation of mitotic cell cycle GO:0007346 126 0.034
regulation of nucleocytoplasmic transport GO:0046822 73 0.034
protein localization to nucleus GO:0034504 121 0.034
regulation of muscle tissue development GO:1901861 97 0.034
organonitrogen compound catabolic process GO:1901565 264 0.034
oocyte axis specification GO:0007309 2 0.033
single organism nuclear import GO:1902593 95 0.033
oxidation reduction process GO:0055114 342 0.033
cellular nitrogen compound catabolic process GO:0044270 280 0.033
embryonic limb morphogenesis GO:0030326 126 0.033
mitotic cell cycle process GO:1903047 159 0.033
sequestering of calcium ion GO:0051208 18 0.033
regulation of membrane potential GO:0042391 192 0.033
wnt signaling pathway GO:0016055 188 0.033
meiotic nuclear division GO:0007126 115 0.033
ribonucleoside monophosphate catabolic process GO:0009158 57 0.033
ribose phosphate metabolic process GO:0019693 291 0.033
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.033
calcium ion transport GO:0006816 159 0.032
regulation of cellular response to stress GO:0080135 159 0.032
cellular protein complex assembly GO:0043623 116 0.032
regulation of circadian sleep wake cycle GO:0042749 3 0.032
tube formation GO:0035148 140 0.032
organelle fission GO:0048285 170 0.032
aromatic compound catabolic process GO:0019439 286 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
regulation of actin cytoskeleton organization GO:0032956 84 0.031
regulation of protein targeting GO:1903533 61 0.031
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
striated muscle hypertrophy GO:0014897 24 0.031
cell type specific apoptotic process GO:0097285 268 0.031
microtubule cytoskeleton organization GO:0000226 157 0.031
establishment or maintenance of cell polarity GO:0007163 86 0.030
negative regulation of protein modification process GO:0031400 163 0.030
placenta development GO:0001890 140 0.030
divalent metal ion transport GO:0070838 172 0.030
regulation of protein import into nucleus GO:0042306 52 0.030
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.030
physiological cardiac muscle hypertrophy GO:0003301 3 0.030
regulation of ion transport GO:0043269 215 0.030
negative regulation of transferase activity GO:0051348 85 0.030
nuclear import GO:0051170 95 0.029
purine nucleoside monophosphate metabolic process GO:0009126 81 0.029
negative regulation of proteolysis GO:0045861 74 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
regulation of blood circulation GO:1903522 93 0.029
cellular lipid metabolic process GO:0044255 323 0.029
protein localization to membrane GO:0072657 108 0.028
embryonic camera type eye development GO:0031076 36 0.028
cellular divalent inorganic cation homeostasis GO:0072503 127 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
single organismal cell cell adhesion GO:0016337 131 0.028
embryonic organ morphogenesis GO:0048562 276 0.028
regulation of cell size GO:0008361 72 0.028
regulation of blood pressure GO:0008217 93 0.027
regulation of kinase activity GO:0043549 249 0.027
bone development GO:0060348 120 0.027
nuclear division GO:0000280 158 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
regulation of protein serine threonine kinase activity GO:0071900 157 0.027
neuron migration GO:0001764 122 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.027
long chain fatty acid import GO:0044539 2 0.027
negative regulation of immune system process GO:0002683 209 0.027
developmental cell growth GO:0048588 84 0.027
regulation of protein maturation GO:1903317 96 0.027
embryonic appendage morphogenesis GO:0035113 126 0.026
regulation of neuron projection development GO:0010975 169 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
response to organic cyclic compound GO:0014070 198 0.026
canonical wnt signaling pathway GO:0060070 130 0.026
carbohydrate transport GO:0008643 62 0.026
cellular chemical homeostasis GO:0055082 215 0.026
digestive system development GO:0055123 200 0.026
ribonucleoside catabolic process GO:0042454 206 0.026
response to acid chemical GO:0001101 111 0.026
sequestering of metal ion GO:0051238 19 0.026
homeostasis of number of cells GO:0048872 210 0.026
respiratory system development GO:0060541 190 0.025
amine metabolic process GO:0009308 45 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
telencephalon development GO:0021537 186 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
regulation of cell projection organization GO:0031344 206 0.025
regulation of protein processing GO:0070613 96 0.025
oligopeptide transmembrane transport GO:0035672 4 0.025
positive regulation of intracellular transport GO:0032388 70 0.024
organelle localization GO:0051640 179 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
regulation of cellular response to growth factor stimulus GO:0090287 82 0.024
cardiac muscle hypertrophy GO:0003300 23 0.024
limb morphogenesis GO:0035108 149 0.024
myotube differentiation GO:0014902 105 0.024
cilium morphogenesis GO:0060271 102 0.024
salivary gland development GO:0007431 37 0.024
carbohydrate metabolic process GO:0005975 230 0.024
reactive oxygen species metabolic process GO:0072593 84 0.024
tubulin complex biogenesis GO:0072668 2 0.024
positive regulation of growth GO:0045927 104 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
positive regulation of cell substrate adhesion GO:0010811 47 0.023
regulation of cell adhesion GO:0030155 154 0.023
Fly
protein modification by small protein conjugation or removal GO:0070647 207 0.023
calcium ion transmembrane transport GO:0070588 85 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
cardiac ventricle morphogenesis GO:0003208 50 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
renal system development GO:0072001 225 0.022
reactive oxygen species biosynthetic process GO:1903409 8 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.022
cellular response to organic cyclic compound GO:0071407 87 0.022
regulation of endocytosis GO:0030100 69 0.022
cardiac ventricle development GO:0003231 83 0.022
digestive tract development GO:0048565 190 0.022
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.022
ribonucleoside monophosphate metabolic process GO:0009161 80 0.022
regulation of secretion GO:0051046 274 0.022
nucleoside monophosphate metabolic process GO:0009123 85 0.022
positive regulation of cytokine production GO:0001819 174 0.022
potassium ion transport GO:0006813 52 0.022
organophosphate catabolic process GO:0046434 232 0.022
regulation of transporter activity GO:0032409 57 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
cellular amino acid metabolic process GO:0006520 103 0.021
positive regulation of cell cycle GO:0045787 92 0.021
protein localization to plasma membrane GO:0072659 57 0.021
negative regulation of kinase activity GO:0033673 81 0.021
negative regulation of homeostatic process GO:0032845 71 0.021
positive regulation of neuron projection development GO:0010976 79 0.021
muscle cell fate specification GO:0042694 1 0.021
regulation of metal ion transport GO:0010959 106 0.021
cellular response to amino acid stimulus GO:0071230 29 0.021
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.021
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.021
regulation of cell cycle process GO:0010564 160 0.021
sensory system development GO:0048880 3 0.021
regulation of ion transmembrane transporter activity GO:0032412 54 0.020
lung development GO:0030324 164 0.020
ossification GO:0001503 216 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
negative regulation of nervous system development GO:0051961 156 0.020
receptor mediated endocytosis GO:0006898 51 0.020
cytosolic calcium ion homeostasis GO:0051480 70 0.020
cerebellum vasculature morphogenesis GO:0061301 1 0.020
salivary gland morphogenesis GO:0007435 33 0.020
compound eye development GO:0048749 1 0.020
hormone secretion GO:0046879 128 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
endomembrane system organization GO:0010256 147 0.020
positive regulation of peptidase activity GO:0010952 49 0.020
nucleotide catabolic process GO:0009166 217 0.020
protein targeting GO:0006605 143 0.020
acetate ester transport GO:1901374 2 0.020
oocyte construction GO:0007308 2 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
protein processing GO:0016485 163 0.019
heart trabecula formation GO:0060347 14 0.019
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.019
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.019
morphogenesis of embryonic epithelium GO:0016331 159 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.019
meiotic cell cycle process GO:1903046 77 0.019
negative regulation of ion transport GO:0043271 28 0.019
regulation of cellular component size GO:0032535 121 0.019
inter male aggressive behavior GO:0002121 3 0.019
regulation of muscle hypertrophy GO:0014743 13 0.019
forebrain cell migration GO:0021885 58 0.019
negative regulation of cell cycle GO:0045786 123 0.019
cell fate specification GO:0001708 72 0.019
purine containing compound metabolic process GO:0072521 311 0.019
mesenchymal cell differentiation GO:0048762 107 0.019
negative regulation of endopeptidase activity GO:0010951 44 0.019
neuron projection extension GO:1990138 64 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
regulation of cardiac muscle contraction GO:0055117 21 0.019
positive regulation of cytoplasmic transport GO:1903651 40 0.019
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.019
cell division GO:0051301 120 0.018
negative regulation of phagocytosis GO:0050765 4 0.018
mesenchymal cell development GO:0014031 93 0.018
regulation of transferase activity GO:0051338 263 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
regulation of bmp signaling pathway GO:0030510 60 0.018
endocytosis GO:0006897 168 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
meiotic cell cycle GO:0051321 122 0.018
positive regulation of secretion by cell GO:1903532 114 0.018
nucleotide metabolic process GO:0009117 332 0.018
myoblast differentiation GO:0045445 52 0.018
negative regulation of cell growth GO:0030308 44 0.018
forebrain development GO:0030900 302 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
cytokinetic process GO:0032506 2 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
regulation of cardiac muscle tissue growth GO:0055021 26 0.018
positive regulation of cell projection organization GO:0031346 95 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
dephosphorylation GO:0016311 129 0.018
bmp signaling pathway GO:0030509 93 0.018
respiratory tube development GO:0030323 167 0.018
signal transduction by p53 class mediator GO:0072331 51 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
telencephalon cell migration GO:0022029 55 0.018
peripheral nervous system axon regeneration GO:0014012 2 0.018
fibril organization GO:0097435 2 0.018
cerebellum development GO:0021549 77 0.018
gene silencing GO:0016458 38 0.017
tissue homeostasis GO:0001894 115 0.017
regionalization GO:0003002 337 0.017
negative regulation of phospholipase activity GO:0010519 4 0.017
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 7 0.017
cation homeostasis GO:0055080 212 0.017
connective tissue development GO:0061448 179 0.017
positive regulation of protein modification process GO:0031401 299 0.017
cognition GO:0050890 149 0.017
epithelial cell proliferation GO:0050673 174 0.017
negative regulation of cell adhesion GO:0007162 45 0.017
regulation of angiogenesis GO:0045765 81 0.017
sodium ion transmembrane transport GO:0035725 49 0.017
protein localization to organelle GO:0033365 185 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
neural tube development GO:0021915 160 0.017
skeletal muscle myosin thick filament assembly GO:0030241 1 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
response to radiation GO:0009314 165 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
potassium ion transmembrane transport GO:0071805 43 0.016
retinal blood vessel morphogenesis GO:0061304 3 0.016
nucleoside monophosphate catabolic process GO:0009125 59 0.016
ear development GO:0043583 200 0.016
embryonic eye morphogenesis GO:0048048 29 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
regulation of reproductive process GO:2000241 66 0.016
exocrine system development GO:0035272 45 0.016
actin myosin filament sliding GO:0033275 1 0.016
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.016
actin polymerization or depolymerization GO:0008154 54 0.016
mitotic cytokinesis GO:0000281 4 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
regulation of myoblast differentiation GO:0045661 29 0.016
mitochondrion organization GO:0007005 134 0.016
positive regulation of kinase activity GO:0033674 155 0.016
cell growth involved in cardiac muscle cell development GO:0061049 3 0.016
regulation of ossification GO:0030278 112 0.016
protein kinase b signaling GO:0043491 74 0.016
response to extracellular stimulus GO:0009991 127 0.016
rna processing GO:0006396 105 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
organic anion transport GO:0015711 137 0.016
fat cell differentiation GO:0045444 160 0.016
neuron death GO:0070997 154 0.015
negative regulation of hepatocyte differentiation GO:0070367 1 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
regulation of actin filament based process GO:0032970 99 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
regulation of calcium ion transport GO:0051924 69 0.015
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.015
erk1 and erk2 cascade GO:0070371 77 0.015
negative regulation of protein maturation GO:1903318 79 0.015
regulation of hormone levels GO:0010817 211 0.015
myofibril assembly GO:0030239 34 0.015
Mouse Fly
positive regulation of cell growth GO:0030307 33 0.015
purine nucleoside monophosphate catabolic process GO:0009128 58 0.015
adult behavior GO:0030534 135 0.015
regulation of androgen receptor signaling pathway GO:0060765 3 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.015
response to uv GO:0009411 44 0.015
multicellular organismal metabolic process GO:0044236 28 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.015
blood coagulation GO:0007596 76 0.015
regulation of ion homeostasis GO:2000021 64 0.015
syncytium formation by plasma membrane fusion GO:0000768 42 0.015
positive regulation of potassium ion transport GO:0043268 3 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
atp metabolic process GO:0046034 75 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
cardiac septum morphogenesis GO:0060411 46 0.014
regulation of skeletal muscle fiber development GO:0048742 36 0.014
striated muscle adaptation GO:0014888 26 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014

Pdlim3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.994
disease of anatomical entity DOID:7 0 0.994
musculoskeletal system disease DOID:17 0 0.994
muscle tissue disease DOID:66 0 0.988
myopathy DOID:423 0 0.942
cardiovascular system disease DOID:1287 0 0.488
heart disease DOID:114 0 0.334
cardiomyopathy DOID:0050700 0 0.334
intrinsic cardiomyopathy DOID:0060036 0 0.288
muscular dystrophy DOID:9884 0 0.154
dilated cardiomyopathy DOID:12930 0 0.064
nervous system disease DOID:863 0 0.039
distal arthrogryposis DOID:0050646 0 0.038
vascular disease DOID:178 0 0.031
hypertrophic cardiomyopathy DOID:11984 0 0.026
artery disease DOID:0050828 0 0.022
central nervous system disease DOID:331 0 0.018