Mus musculus

0 known processes

Pef1

penta-EF hand domain containing 1

(Aliases: 2600002E23Rik,Peflin)

Pef1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macroautophagy GO:0016236 21 0.513
microtubule based process GO:0007017 236 0.244
establishment of melanosome localization GO:0032401 11 0.207
endomembrane system organization GO:0010256 147 0.198
organelle assembly GO:0070925 177 0.160
synaptic transmission GO:0007268 329 0.156
positive regulation of triglyceride lipase activity GO:0061365 3 0.145
glycerolipid metabolic process GO:0046486 122 0.121
cellular response to extracellular stimulus GO:0031668 81 0.120
membrane organization GO:0061024 245 0.116
vesicle localization GO:0051648 86 0.116
response to starvation GO:0042594 65 0.105
regulation of cellular component biogenesis GO:0044087 181 0.103
virion assembly GO:0019068 1 0.102
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.098
cellular amino acid metabolic process GO:0006520 103 0.095
melanosome localization GO:0032400 12 0.087
cellular response to starvation GO:0009267 57 0.086
autophagic vacuole assembly GO:0000045 13 0.085
organelle localization GO:0051640 179 0.083
cilium morphogenesis GO:0060271 102 0.082
protein modification by small protein conjugation GO:0032446 187 0.081
cellular ketone metabolic process GO:0042180 84 0.081
regulation of vacuole organization GO:0044088 4 0.080
protein localization to membrane GO:0072657 108 0.079
axoneme assembly GO:0035082 15 0.074
cellular response to nutrient levels GO:0031669 64 0.069
regulation of organelle organization GO:0033043 289 0.064
endocytosis GO:0006897 168 0.063
protein localization to plasma membrane GO:0072659 57 0.061
autophagy GO:0006914 45 0.060
regulation of secretion by cell GO:1903530 249 0.060
Mouse
positive regulation of secretion GO:0051047 130 0.060
Mouse
regulation of synaptic plasticity GO:0048167 87 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
regulation of hydrolase activity GO:0051336 246 0.057
Mouse
cellular amine metabolic process GO:0044106 44 0.057
protein ubiquitination GO:0016567 171 0.056
protein targeting to membrane GO:0006612 20 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.053
cytoplasmic transport GO:0016482 234 0.052
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.052
gtp metabolic process GO:0046039 144 0.052
guanosine containing compound metabolic process GO:1901068 144 0.051
central nervous system neuron differentiation GO:0021953 162 0.051
glycosyl compound catabolic process GO:1901658 206 0.051
t cell activation GO:0042110 289 0.050
macromolecule catabolic process GO:0009057 281 0.049
microtubule cytoskeleton organization GO:0000226 157 0.049
mapk cascade GO:0000165 281 0.049
regulation of cellular catabolic process GO:0031329 242 0.049
regulation of proteolysis GO:0030162 164 0.048
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.047
negative regulation of cellular component organization GO:0051129 194 0.046
ubiquitin dependent protein catabolic process GO:0006511 129 0.045
pigment granule localization GO:0051875 13 0.043
positive regulation of cell death GO:0010942 224 0.041
Mouse
maintenance of location GO:0051235 89 0.041
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.040
intracellular protein transport GO:0006886 204 0.040
Mouse
protein secretion GO:0009306 111 0.039
positive regulation of secretion by cell GO:1903532 114 0.038
Mouse
protein maturation GO:0051604 176 0.038
Mouse
regulation of establishment of protein localization GO:0070201 181 0.038
Mouse
neuron apoptotic process GO:0051402 142 0.038
regulation of cell projection organization GO:0031344 206 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
carbohydrate derivative catabolic process GO:1901136 231 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
carbohydrate homeostasis GO:0033500 128 0.036
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.035
cellular response to external stimulus GO:0071496 88 0.035
response to extracellular stimulus GO:0009991 127 0.035
positive regulation of protein modification process GO:0031401 299 0.034
response to growth factor GO:0070848 198 0.034
negative regulation of molecular function GO:0044092 258 0.033
Mouse
purine nucleotide metabolic process GO:0006163 302 0.033
regulation of protein maturation GO:1903317 96 0.033
nitrogen compound transport GO:0071705 271 0.032
Mouse
gtp catabolic process GO:0006184 143 0.032
positive regulation of neuron differentiation GO:0045666 141 0.032
peptide transport GO:0015833 133 0.031
Mouse
negative regulation of nervous system development GO:0051961 156 0.031
spermatogenesis GO:0007283 284 0.031
response to organic cyclic compound GO:0014070 198 0.031
pigmentation GO:0043473 71 0.030
establishment of pigment granule localization GO:0051905 12 0.030
cell type specific apoptotic process GO:0097285 268 0.030
negative regulation of protein metabolic process GO:0051248 282 0.029
small gtpase mediated signal transduction GO:0007264 97 0.029
guanosine containing compound catabolic process GO:1901069 144 0.029
regulation of mapk cascade GO:0043408 248 0.029
organophosphate catabolic process GO:0046434 232 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
regulation of lipoprotein lipase activity GO:0051004 4 0.028
regulation of cell cycle GO:0051726 281 0.028
response to organonitrogen compound GO:0010243 246 0.027
cellular response to cytokine stimulus GO:0071345 189 0.027
establishment of organelle localization GO:0051656 122 0.027
plasma membrane organization GO:0007009 90 0.027
cerebral cortex cell migration GO:0021795 44 0.027
regulation of gtp catabolic process GO:0033124 113 0.027
adult behavior GO:0030534 135 0.027
cellular ion homeostasis GO:0006873 165 0.027
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.027
negative regulation of protein processing GO:0010955 79 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
sensory system development GO:0048880 3 0.027
regulation of autophagic vacuole assembly GO:2000785 4 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
regulation of endocytosis GO:0030100 69 0.026
ras protein signal transduction GO:0007265 77 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
cell adhesion GO:0007155 329 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
actin cytoskeleton organization GO:0030036 220 0.026
negative regulation of proteolysis GO:0045861 74 0.026
regulation of macroautophagy GO:0016241 12 0.025
golgi vesicle transport GO:0048193 30 0.025
heterocycle catabolic process GO:0046700 280 0.025
organic acid transport GO:0015849 101 0.025
negative regulation of cell cycle GO:0045786 123 0.025
negative regulation of neuron death GO:1901215 98 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
Mouse
response to nutrient levels GO:0031667 109 0.025
rho protein signal transduction GO:0007266 32 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
tissue homeostasis GO:0001894 115 0.025
cellular carbohydrate metabolic process GO:0044262 119 0.025
cation transport GO:0006812 399 0.025
Mouse
aromatic compound catabolic process GO:0019439 286 0.024
amine metabolic process GO:0009308 45 0.024
regulation of cell motility GO:2000145 236 0.024
regulation of nucleotide metabolic process GO:0006140 169 0.024
regulation of kinase activity GO:0043549 249 0.024
positive regulation of homeostatic process GO:0032846 64 0.024
Mouse
nucleotide catabolic process GO:0009166 217 0.023
establishment of protein localization to membrane GO:0090150 54 0.023
regulation of protein localization GO:0032880 231 0.023
Mouse
cellular lipid metabolic process GO:0044255 323 0.023
regulation of pancreatic juice secretion GO:0090186 4 0.022
amide transport GO:0042886 138 0.022
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.022
Mouse
negative regulation of synapse assembly GO:0051964 3 0.022
neuron death GO:0070997 154 0.022
apoptotic signaling pathway GO:0097190 306 0.022
camera type eye development GO:0043010 266 0.021
transmembrane transport GO:0055085 412 0.021
regulation of cellular response to stress GO:0080135 159 0.021
leukocyte proliferation GO:0070661 172 0.021
anion transport GO:0006820 177 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
regulation of lymphocyte activation GO:0051249 240 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
peripheral nervous system development GO:0007422 53 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
purine containing compound metabolic process GO:0072521 311 0.020
regulation of protein transport GO:0051223 163 0.020
Mouse
multicellular organism growth GO:0035264 161 0.020
leukocyte differentiation GO:0002521 342 0.020
regulation of neuron differentiation GO:0045664 281 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
regulation of ras protein signal transduction GO:0046578 114 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
peptidyl glutamic acid modification GO:0018200 13 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
regulation of hormone levels GO:0010817 211 0.019
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.019
glycerolipid biosynthetic process GO:0045017 50 0.019
protein catabolic process GO:0030163 221 0.019
purine containing compound catabolic process GO:0072523 213 0.019
regulation of homeostatic process GO:0032844 182 0.019
Mouse
cell chemotaxis GO:0060326 81 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
positive regulation of protein secretion GO:0050714 52 0.018
acetylcholine transport GO:0015870 2 0.018
regulation of secretion GO:0051046 274 0.018
Mouse
vesicle fusion GO:0006906 16 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
regulation of cell activation GO:0050865 289 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
nucleoside metabolic process GO:0009116 246 0.017
spermatid differentiation GO:0048515 115 0.017
nucleoside catabolic process GO:0009164 206 0.017
protein processing GO:0016485 163 0.017
Mouse
actin filament organization GO:0007015 113 0.017
positive regulation of insulin secretion GO:0032024 26 0.017
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.017
metal ion homeostasis GO:0055065 189 0.017
Mouse
regulation of hormone secretion GO:0046883 88 0.017
Mouse
regulation of protein processing GO:0070613 96 0.017
regulation of neuron death GO:1901214 134 0.017
pigment granule transport GO:0051904 12 0.017
protein targeting GO:0006605 143 0.017
Mouse
lymphocyte differentiation GO:0030098 242 0.017
germ cell development GO:0007281 185 0.017
vesicle organization GO:0016050 60 0.016
cellular homeostasis GO:0019725 240 0.016
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
regulation of peptide hormone secretion GO:0090276 75 0.016
Mouse
negative regulation of organelle organization GO:0010639 90 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
acetate ester transport GO:1901374 2 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
Mouse
nucleotide metabolic process GO:0009117 332 0.016
positive regulation of protein transport GO:0051222 93 0.016
defense response to other organism GO:0098542 197 0.016
gliogenesis GO:0042063 141 0.016
lateral line system development GO:0048925 1 0.016
skin development GO:0043588 220 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
very long chain fatty acid metabolic process GO:0000038 8 0.016
melanosome transport GO:0032402 11 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
calcium ion transport GO:0006816 159 0.015
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.015
positive regulation of lipoprotein lipase activity GO:0051006 3 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
regulation of protein kinase activity GO:0045859 232 0.015
asymmetric neuroblast division GO:0055059 1 0.015
negative regulation of protein modification process GO:0031400 163 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
synapse organization GO:0050808 125 0.015
regulation of anatomical structure size GO:0090066 178 0.015
response to epidermal growth factor GO:0070849 4 0.015
acid secretion GO:0046717 33 0.015
mitotic cell cycle GO:0000278 195 0.015
synapse assembly GO:0007416 56 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
Mouse
oxidation reduction process GO:0055114 342 0.014
regulation of cell shape GO:0008360 39 0.014
negative regulation of macrophage activation GO:0043031 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
male gamete generation GO:0048232 285 0.014
regulation of ion transport GO:0043269 215 0.014
Mouse
myeloid cell differentiation GO:0030099 233 0.014
histone modification GO:0016570 159 0.014
cellular glucan metabolic process GO:0006073 32 0.014
homeostasis of number of cells GO:0048872 210 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
lipid modification GO:0030258 65 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
negative regulation of secretion GO:0051048 61 0.014
lipid localization GO:0010876 126 0.014
golgi to endosome transport GO:0006895 3 0.014
cellular pigmentation GO:0033059 20 0.014
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
negative regulation of protein maturation GO:1903318 79 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
forebrain cell migration GO:0021885 58 0.013
response to inorganic substance GO:0010035 96 0.013
Human Mouse
glucan metabolic process GO:0044042 32 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
neural precursor cell proliferation GO:0061351 121 0.013
neutral lipid metabolic process GO:0006638 57 0.013
carboxylic acid transport GO:0046942 100 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
regulation of protein secretion GO:0050708 82 0.013
dicarboxylic acid transport GO:0006835 29 0.013
positive regulation of organelle organization GO:0010638 128 0.013
organic anion transport GO:0015711 137 0.013
ameboidal type cell migration GO:0001667 128 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
Mouse
regulation of lipid metabolic process GO:0019216 118 0.013
response to radiation GO:0009314 165 0.013
establishment of vesicle localization GO:0051650 81 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
regulation of t cell activation GO:0050863 170 0.013
divalent inorganic cation transport GO:0072511 178 0.013
Mouse
positive regulation of cell cycle GO:0045787 92 0.012
negative regulation of cell projection organization GO:0031345 56 0.012
protein localization to cell leading edge GO:1902463 1 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
organelle fission GO:0048285 170 0.012
glial cell development GO:0021782 54 0.012
glial cell differentiation GO:0010001 131 0.012
positive regulation of cell development GO:0010720 237 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
protein localization to organelle GO:0033365 185 0.012
Mouse
asymmetric stem cell division GO:0098722 3 0.012
cell fate commitment GO:0045165 210 0.012
cytokine production GO:0001816 319 0.012
compound eye development GO:0048749 1 0.012
lipid biosynthetic process GO:0008610 179 0.012
regulation of cell migration GO:0030334 219 0.012
peptide hormone secretion GO:0030072 109 0.012
Mouse
regulation of protein stability GO:0031647 52 0.012
single organism cell adhesion GO:0098602 156 0.012
sensory organ morphogenesis GO:0090596 242 0.012
cellular protein catabolic process GO:0044257 155 0.012
positive regulation of leukocyte proliferation GO:0070665 73 0.012
cytosolic calcium ion homeostasis GO:0051480 70 0.012
Mouse
ribose phosphate metabolic process GO:0019693 291 0.012
carbohydrate metabolic process GO:0005975 230 0.012
fatty acid metabolic process GO:0006631 121 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
arp2 3 complex mediated actin nucleation GO:0034314 3 0.012
spermatid development GO:0007286 108 0.012
negative regulation of growth GO:0045926 99 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
cranial nerve formation GO:0021603 4 0.011
neuron migration GO:0001764 122 0.011
inflammatory response GO:0006954 244 0.011
energy reserve metabolic process GO:0006112 39 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
regulation of actin nucleation GO:0051125 4 0.011
ion transmembrane transport GO:0034220 361 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
positive regulation of lamellipodium organization GO:1902745 3 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
Mouse
regulation of cellular component size GO:0032535 121 0.011
schwann cell differentiation GO:0014037 26 0.011
negative regulation of cell development GO:0010721 169 0.011
cellular polysaccharide metabolic process GO:0044264 38 0.011
positive regulation of cell activation GO:0050867 158 0.011
regulation of cytokine production GO:0001817 266 0.011
phosphatidic acid biosynthetic process GO:0006654 2 0.011
skeletal system development GO:0001501 356 0.011
exocytosis GO:0006887 121 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
axonogenesis GO:0007409 274 0.011
regulation of membrane potential GO:0042391 192 0.010
establishment of protein localization to plasma membrane GO:0090002 34 0.010
peptidyl threonine phosphorylation GO:0018107 31 0.010
telencephalon cell migration GO:0022029 55 0.010
angiogenesis GO:0001525 201 0.010
succinate transport GO:0015744 1 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
regulation of map kinase activity GO:0043405 120 0.010
axon cargo transport GO:0008088 33 0.010
protein autophosphorylation GO:0046777 61 0.010
regulation of peptide secretion GO:0002791 77 0.010
Mouse
ribonucleotide catabolic process GO:0009261 208 0.010
negative regulation of secretion by cell GO:1903531 54 0.010
mitochondrion organization GO:0007005 134 0.010
peptidyl threonine modification GO:0018210 31 0.010
glucose homeostasis GO:0042593 128 0.010
Mouse
regulation of cell size GO:0008361 72 0.010
regulation of actin filament based process GO:0032970 99 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
cellular response to lipid GO:0071396 145 0.010
hormone secretion GO:0046879 128 0.010
Mouse
multi multicellular organism process GO:0044706 109 0.010

Pef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.034
disease of anatomical entity DOID:7 0 0.034
hematopoietic system disease DOID:74 0 0.034
disease of metabolism DOID:0014667 0 0.016