Mus musculus

0 known processes

Pex6

peroxisomal biogenesis factor 6

(Aliases: MGC6455,D130055I09Rik,mKIAA4177,KIAA4177,AI132582)

Pex6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 191 0.159
positive regulation of cholesterol homeostasis GO:2000189 2 0.126
regulation of cellular ketone metabolic process GO:0010565 66 0.116
regulation of fatty acid metabolic process GO:0019217 28 0.116
cellular lipid metabolic process GO:0044255 323 0.105
regulation of cholesterol homeostasis GO:2000188 9 0.099
cellular ketone metabolic process GO:0042180 84 0.091
heart morphogenesis GO:0003007 178 0.085
rhythmic process GO:0048511 174 0.083
histone modification GO:0016570 159 0.076
gland development GO:0048732 330 0.075
lipid localization GO:0010876 126 0.074
lipid homeostasis GO:0055088 63 0.074
nitrogen compound transport GO:0071705 271 0.073
cellular response to hormone stimulus GO:0032870 150 0.070
transmission of nerve impulse GO:0019226 76 0.070
skin development GO:0043588 220 0.069
ras protein signal transduction GO:0007265 77 0.068
positive regulation of translational initiation by iron GO:0045994 2 0.068
nucleobase containing small molecule metabolic process GO:0055086 352 0.067
Human Yeast
amide transport GO:0042886 138 0.065
negative regulation of nervous system development GO:0051961 156 0.060
fatty acid metabolic process GO:0006631 121 0.060
positive regulation of cholesterol biosynthetic process GO:0045542 3 0.059
glycerolipid metabolic process GO:0046486 122 0.058
peptide secretion GO:0002790 114 0.057
anion transport GO:0006820 177 0.056
covalent chromatin modification GO:0016569 163 0.055
urogenital system development GO:0001655 261 0.053
embryonic placenta development GO:0001892 98 0.052
negative regulation of phosphate metabolic process GO:0045936 184 0.052
lipid biosynthetic process GO:0008610 179 0.051
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.051
segmentation GO:0035282 93 0.051
regionalization GO:0003002 337 0.051
epidermis development GO:0008544 187 0.050
regulation of homeostatic process GO:0032844 182 0.049
peptide hormone secretion GO:0030072 109 0.048
appendage development GO:0048736 166 0.048
regulation of lipid metabolic process GO:0019216 118 0.047
cellular response to peptide hormone stimulus GO:0071375 92 0.047
cardiac chamber morphogenesis GO:0003206 93 0.047
organic acid transport GO:0015849 101 0.046
skeletal system development GO:0001501 356 0.046
protein modification by small protein conjugation or removal GO:0070647 207 0.046
coenzyme catabolic process GO:0009109 5 0.044
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.043
digestive system development GO:0055123 200 0.040
cellular response to acid chemical GO:0071229 68 0.040
single organismal cell cell adhesion GO:0016337 131 0.040
limb development GO:0060173 166 0.040
muscle system process GO:0003012 141 0.040
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.039
regulation of peptide transport GO:0090087 91 0.039
camera type eye development GO:0043010 266 0.039
gastrulation GO:0007369 116 0.038
organonitrogen compound catabolic process GO:1901565 264 0.038
Human Yeast
purine ribonucleotide catabolic process GO:0009154 208 0.038
Human Yeast
response to acid chemical GO:0001101 111 0.037
regulation of cellular amine metabolic process GO:0033238 20 0.037
digestive tract development GO:0048565 190 0.037
muscle cell differentiation GO:0042692 261 0.037
cytokine production GO:0001816 319 0.037
amine metabolic process GO:0009308 45 0.037
lytic vacuole organization GO:0080171 21 0.037
regulation of translational initiation by iron GO:0006447 2 0.036
regulation of hormone levels GO:0010817 211 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.036
positive regulation of protein modification process GO:0031401 299 0.036
chromatin modification GO:0016568 187 0.034
peptide transport GO:0015833 133 0.034
regulation of cholesterol metabolic process GO:0090181 14 0.034
positive regulation of lipoprotein lipase activity GO:0051006 3 0.034
positive regulation of cell development GO:0010720 237 0.033
response to peptide hormone GO:0043434 127 0.033
multicellular organism growth GO:0035264 161 0.033
regulation of secretion GO:0051046 274 0.033
response to peptide GO:1901652 136 0.032
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
cellular homeostasis GO:0019725 240 0.032
ribonucleotide metabolic process GO:0009259 291 0.032
Human Yeast
lateral inhibition GO:0046331 1 0.032
maintenance of location GO:0051235 89 0.032
cellular amino acid metabolic process GO:0006520 103 0.032
defense response to other organism GO:0098542 197 0.031
muscle tissue morphogenesis GO:0060415 53 0.031
response to retinoic acid GO:0032526 56 0.031
smoothened signaling pathway GO:0007224 105 0.031
regulation of cellular catabolic process GO:0031329 242 0.030
small gtpase mediated signal transduction GO:0007264 97 0.030
sensory perception GO:0007600 245 0.030
telencephalon development GO:0021537 186 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
cellular response to lipid GO:0071396 145 0.030
modification dependent macromolecule catabolic process GO:0043632 133 0.030
epithelial tube morphogenesis GO:0060562 303 0.029
carboxylic acid transport GO:0046942 100 0.029
cellular response to peptide GO:1901653 92 0.029
cellular response to organonitrogen compound GO:0071417 145 0.028
sterol homeostasis GO:0055092 45 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
Human Yeast
placenta development GO:0001890 140 0.028
cardiac ventricle development GO:0003231 83 0.028
positive regulation of translational initiation GO:0045948 4 0.028
purine containing compound catabolic process GO:0072523 213 0.028
Human Yeast
muscle tissue development GO:0060537 308 0.028
multi multicellular organism process GO:0044706 109 0.027
nucleotide metabolic process GO:0009117 332 0.027
Human Yeast
cytokine mediated signaling pathway GO:0019221 115 0.027
ensheathment of neurons GO:0007272 76 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
blood vessel morphogenesis GO:0048514 285 0.026
nucleoside bisphosphate metabolic process GO:0033865 9 0.026
response to monosaccharide GO:0034284 67 0.026
regulation of defense response GO:0031347 233 0.026
pallium development GO:0021543 120 0.025
oxidation reduction process GO:0055114 342 0.025
cholesterol homeostasis GO:0042632 44 0.025
epithelial cell proliferation GO:0050673 174 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
Human Yeast
ribose phosphate metabolic process GO:0019693 291 0.025
Human Yeast
response to organonitrogen compound GO:0010243 246 0.025
organic anion transport GO:0015711 137 0.025
negative regulation of molecular function GO:0044092 258 0.025
regulation of organelle organization GO:0033043 289 0.025
regulation of protein catabolic process GO:0042176 108 0.025
regulation of antimicrobial humoral response GO:0002759 3 0.025
respiratory tube development GO:0030323 167 0.024
chromatin organization GO:0006325 206 0.024
immune effector process GO:0002252 321 0.024
neuron migration GO:0001764 122 0.024
antimicrobial peptide production GO:0002775 2 0.024
endocytosis GO:0006897 168 0.024
vacuole organization GO:0007033 38 0.024
kidney development GO:0001822 213 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
response to light stimulus GO:0009416 135 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
embryonic organ morphogenesis GO:0048562 276 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
Human Yeast
protein ubiquitination GO:0016567 171 0.023
maternal process involved in female pregnancy GO:0060135 32 0.023
regulation of peptide secretion GO:0002791 77 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
cardiac chamber development GO:0003205 108 0.023
detection of temperature stimulus involved in sensory perception of pain GO:0050965 6 0.023
fatty acyl coa metabolic process GO:0035337 4 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
fertilization GO:0009566 127 0.023
regulation of cytokine production GO:0001817 266 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
neutral lipid metabolic process GO:0006638 57 0.022
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.022
organ growth GO:0035265 117 0.022
compound eye development GO:0048749 1 0.022
regulation of lipoprotein lipase activity GO:0051004 4 0.022
actin cytoskeleton organization GO:0030036 220 0.021
regulation of leukocyte differentiation GO:1902105 159 0.021
positive regulation of triglyceride lipase activity GO:0061365 3 0.021
phospholipid homeostasis GO:0055091 6 0.021
glucose homeostasis GO:0042593 128 0.021
transmembrane transport GO:0055085 412 0.021
Human Yeast
positive regulation of protein transport GO:0051222 93 0.021
striated muscle tissue development GO:0014706 293 0.021
membrane lipid metabolic process GO:0006643 53 0.021
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.021
regulation of cell motility GO:2000145 236 0.020
nucleoside catabolic process GO:0009164 206 0.020
Human Yeast
bone development GO:0060348 120 0.020
positive regulation of cellular protein catabolic process GO:1903364 34 0.020
cytokine biosynthetic process GO:0042089 68 0.020
cardiocyte differentiation GO:0035051 87 0.020
acyl coa metabolic process GO:0006637 19 0.020
learning or memory GO:0007611 148 0.020
neuronal action potential GO:0019228 54 0.020
placenta blood vessel development GO:0060674 31 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
epithelial tube formation GO:0072175 130 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.019
Human Yeast
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
forebrain development GO:0030900 302 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.019
cell differentiation involved in embryonic placenta development GO:0060706 26 0.019
insulin secretion GO:0030073 89 0.019
response to molecule of bacterial origin GO:0002237 143 0.018
positive regulation of cytokine production GO:0001819 174 0.018
forebrain regionalization GO:0021871 25 0.018
acylglycerol homeostasis GO:0055090 16 0.018
regulation of circadian rhythm GO:0042752 58 0.018
determination of heart left right asymmetry GO:0061371 48 0.018
heart growth GO:0060419 45 0.018
regulation of secretion by cell GO:1903530 249 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
regulation of ral protein signal transduction GO:0032485 4 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
membrane organization GO:0061024 245 0.018
negative regulation of synapse assembly GO:0051964 3 0.018
intracellular receptor signaling pathway GO:0030522 74 0.018
neuron neuron synaptic transmission GO:0007270 69 0.018
germ cell development GO:0007281 185 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
t cell activation GO:0042110 289 0.017
locomotory behavior GO:0007626 195 0.017
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
Human Yeast
protein glycosylation GO:0006486 55 0.017
positive regulation of proteolysis GO:0045862 85 0.017
response to nutrient levels GO:0031667 109 0.017
negative regulation of multi organism process GO:0043901 68 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
metencephalon development GO:0022037 89 0.017
fatty acid transmembrane transport GO:1902001 1 0.017
cation transport GO:0006812 399 0.017
ion transmembrane transport GO:0034220 361 0.017
regulation of membrane potential GO:0042391 192 0.017
peptidyl amino acid modification GO:0018193 336 0.017
protein oligomerization GO:0051259 67 0.017
triglyceride homeostasis GO:0070328 15 0.016
sterol metabolic process GO:0016125 58 0.016
cell adhesion GO:0007155 329 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
Human Yeast
methylation GO:0032259 134 0.016
negative regulation of defense response GO:0031348 77 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
Human Yeast
tube formation GO:0035148 140 0.016
acid secretion GO:0046717 33 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
Human Yeast
inflammatory response GO:0006954 244 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
Human Yeast
myelination GO:0042552 74 0.016
protein deubiquitination GO:0016579 19 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
regulation of peptide hormone secretion GO:0090276 75 0.016
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.015
response to radiation GO:0009314 165 0.015
cellular amine metabolic process GO:0044106 44 0.015
intracellular protein transport GO:0006886 204 0.015
Human Yeast
regulation of anatomical structure size GO:0090066 178 0.015
embryonic heart tube development GO:0035050 65 0.015
lipid transport GO:0006869 98 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
Human Yeast
regulation of reproductive process GO:2000241 66 0.015
palate development GO:0060021 76 0.015
negative regulation of cell development GO:0010721 169 0.015
regulation of protein complex assembly GO:0043254 83 0.015
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
positive regulation of fatty acid oxidation GO:0046321 4 0.015
protein catabolic process GO:0030163 221 0.015
neural tube development GO:0021915 160 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
translation GO:0006412 93 0.015
organelle fission GO:0048285 170 0.014
cellular protein catabolic process GO:0044257 155 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
small molecule catabolic process GO:0044282 71 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
regulation of defense response to bacterium GO:1900424 3 0.014
glycerolipid biosynthetic process GO:0045017 50 0.014
apoptotic signaling pathway GO:0097190 306 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
Human Yeast
positive regulation of cholesterol metabolic process GO:0090205 3 0.014
acylglycerol metabolic process GO:0006639 55 0.014
lysosome organization GO:0007040 21 0.014
detection of temperature stimulus involved in sensory perception GO:0050961 6 0.014
cardiac muscle contraction GO:0060048 32 0.014
hormone secretion GO:0046879 128 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
protein processing GO:0016485 163 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
regulation of neuron projection development GO:0010975 169 0.014
regulation of cell projection organization GO:0031344 206 0.014
multicellular organismal signaling GO:0035637 91 0.014
renal system development GO:0072001 225 0.013
regulation of t cell proliferation GO:0042129 92 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
regulation of system process GO:0044057 200 0.013
coenzyme metabolic process GO:0006732 52 0.013
circadian rhythm GO:0007623 114 0.013
metal ion homeostasis GO:0055065 189 0.013
regulation of smoothened signaling pathway GO:0008589 58 0.013
transcription from rna polymerase iii promoter GO:0006383 3 0.013
action potential GO:0001508 78 0.013
smad protein signal transduction GO:0060395 21 0.013
regulation of endocytosis GO:0030100 69 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
Human Yeast
heterocycle catabolic process GO:0046700 280 0.013
Human Yeast
positive regulation of t cell activation GO:0050870 101 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.013
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.013
response to temperature stimulus GO:0009266 55 0.013
single organism cell adhesion GO:0098602 156 0.013
response to extracellular stimulus GO:0009991 127 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
lymphocyte homeostasis GO:0002260 64 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
regulation of cell activation GO:0050865 289 0.013
hindbrain development GO:0030902 128 0.012
aromatic compound catabolic process GO:0019439 286 0.012
Human Yeast
insulin receptor signaling pathway GO:0008286 49 0.012
somitogenesis GO:0001756 69 0.012
negative regulation of cytokine production GO:0001818 84 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
regulation of intracellular transport GO:0032386 159 0.012
interferon beta biosynthetic process GO:0045350 4 0.012
striated muscle cell proliferation GO:0014855 39 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
Human Yeast
negative regulation of growth GO:0045926 99 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
Human Yeast
response to organic cyclic compound GO:0014070 198 0.012
defense response to bacterium GO:0042742 119 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
regulation of proteolysis GO:0030162 164 0.012
stem cell differentiation GO:0048863 268 0.012
cellular response to retinoic acid GO:0071300 25 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
respiratory system development GO:0060541 190 0.012
macromolecule catabolic process GO:0009057 281 0.012
negative regulation of endothelial cell migration GO:0010596 4 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
Human Yeast
regulation of nucleotide metabolic process GO:0006140 169 0.012
leukocyte homeostasis GO:0001776 79 0.012
negative regulation of proteolysis GO:0045861 74 0.012
anatomical structure homeostasis GO:0060249 145 0.012
cytokine metabolic process GO:0042107 71 0.012
cerebellum development GO:0021549 77 0.012
cellular ion homeostasis GO:0006873 165 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
Human Yeast
negative regulation of neuron differentiation GO:0045665 101 0.012
anion transmembrane transport GO:0098656 71 0.012
prostate glandular acinus development GO:0060525 12 0.011
organophosphate catabolic process GO:0046434 232 0.011
Human Yeast
neural tube formation GO:0001841 108 0.011
trophoblast giant cell differentiation GO:0060707 15 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
hormone metabolic process GO:0042445 86 0.011
dendrite development GO:0016358 115 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
Human Yeast
regulation of t cell activation GO:0050863 170 0.011
regulation of response to wounding GO:1903034 189 0.011
skeletal muscle organ development GO:0060538 163 0.011
negative regulation of interferon beta production GO:0032688 3 0.011
positive regulation of reverse cholesterol transport GO:1903064 1 0.011
stem cell development GO:0048864 219 0.011
positive regulation of mitotic cell cycle embryonic GO:0045977 2 0.011
steroid metabolic process GO:0008202 119 0.011
regulation of protein localization GO:0032880 231 0.011
response to insulin GO:0032868 100 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
cation homeostasis GO:0055080 212 0.011
positive regulation of endocytosis GO:0045807 42 0.011
muscle cell proliferation GO:0033002 52 0.011
bile acid secretion GO:0032782 2 0.011
axon ensheathment GO:0008366 76 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
cerebral cortex development GO:0021987 86 0.011
homeostasis of number of cells GO:0048872 210 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
ventricular cardiac muscle cell differentiation GO:0055012 17 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
Human Yeast
nucleoside phosphate catabolic process GO:1901292 222 0.011
Human Yeast
glycosylation GO:0070085 62 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
regulation of cytokine biosynthetic process GO:0042035 59 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
cardiac ventricle morphogenesis GO:0003208 50 0.011
cellular response to salt stress GO:0071472 1 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
monocarboxylic acid transport GO:0015718 44 0.011
regulation of cellular component size GO:0032535 121 0.011
positive regulation of secretion by cell GO:1903532 114 0.010
ketone body metabolic process GO:1902224 3 0.010
regulation of cell adhesion GO:0030155 154 0.010
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.010
positive regulation of ion transport GO:0043270 65 0.010
regulation of cell cycle GO:0051726 281 0.010
synaptonemal complex assembly GO:0007130 13 0.010
protein import GO:0017038 101 0.010
Human Yeast
venous blood vessel development GO:0060841 13 0.010
sensory perception of pain GO:0019233 47 0.010
glandular epithelial cell differentiation GO:0002067 38 0.010
hindbrain morphogenesis GO:0021575 46 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
somite development GO:0061053 81 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
small molecule biosynthetic process GO:0044283 132 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
prostate gland development GO:0030850 48 0.010
ventricular cardiac muscle tissue development GO:0003229 38 0.010
cardiac muscle cell proliferation GO:0060038 31 0.010
regulation of antimicrobial peptide production GO:0002784 1 0.010
fatty acid transport GO:0015908 28 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.010
glycoprotein metabolic process GO:0009100 116 0.010
cardiac muscle tissue growth GO:0055017 37 0.010
positive regulation of cytokine biosynthetic process GO:0042108 40 0.010
protein lipidation GO:0006497 28 0.010
sensory perception of temperature stimulus GO:0050951 9 0.010
tissue homeostasis GO:0001894 115 0.010

Pex6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.056
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.023
disease of anatomical entity DOID:7 0 0.023
brain disease DOID:936 0 0.010