Mus musculus

0 known processes

Pf4

platelet factor 4

(Aliases: Scyb4,Cxcl4)

Pf4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood coagulation GO:0007596 76 0.548
Human
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.350
positive regulation of cytokine production GO:0001819 174 0.270
Human
regulation of cytokine production GO:0001817 266 0.246
Human Mouse
inflammatory response GO:0006954 244 0.235
Mouse
wound healing GO:0042060 157 0.184
Human
defense response to bacterium GO:0042742 119 0.179
Mouse
response to molecule of bacterial origin GO:0002237 143 0.171
Mouse
cell adhesion GO:0007155 329 0.162
defense response to other organism GO:0098542 197 0.156
Mouse
cellular homeostasis GO:0019725 240 0.153
cytokine secretion GO:0050663 72 0.150
cellular ketone metabolic process GO:0042180 84 0.144
regulation of body fluid levels GO:0050878 162 0.141
Human
single organism cell adhesion GO:0098602 156 0.141
g protein coupled receptor signaling pathway GO:0007186 243 0.137
cytokine production GO:0001816 319 0.134
Human Mouse
fatty acid metabolic process GO:0006631 121 0.131
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.130
ras protein signal transduction GO:0007265 77 0.127
t cell activation GO:0042110 289 0.119
regulation of secretion GO:0051046 274 0.117
regulation of response to wounding GO:1903034 189 0.113
immune effector process GO:0002252 321 0.113
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.111
granulocyte migration GO:0097530 43 0.111
Mouse
fat cell differentiation GO:0045444 160 0.111
regulation of tumor necrosis factor production GO:0032680 49 0.111
Human
leukocyte mediated immunity GO:0002443 174 0.107
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.107
membrane organization GO:0061024 245 0.104
regulation of cellular amine metabolic process GO:0033238 20 0.103
rho protein signal transduction GO:0007266 32 0.102
metal ion homeostasis GO:0055065 189 0.101
defense response to gram positive bacterium GO:0050830 50 0.100
negative regulation of immune system process GO:0002683 209 0.098
Human
leukocyte differentiation GO:0002521 342 0.090
Human
regulation of map kinase activity GO:0043405 120 0.090
cellular amino acid metabolic process GO:0006520 103 0.089
mapk cascade GO:0000165 281 0.089
blood circulation GO:0008015 195 0.088
regulation of lymphocyte activation GO:0051249 240 0.088
regulation of cell activation GO:0050865 289 0.088
amine metabolic process GO:0009308 45 0.086
regulation of cellular amino acid metabolic process GO:0006521 5 0.084
small gtpase mediated signal transduction GO:0007264 97 0.082
unsaturated fatty acid metabolic process GO:0033559 31 0.082
cellular metal ion homeostasis GO:0006875 151 0.081
positive regulation of apoptotic process GO:0043065 217 0.080
cellular ion homeostasis GO:0006873 165 0.079
positive regulation of secretion GO:0051047 130 0.079
lymphocyte mediated immunity GO:0002449 139 0.078
cellular lipid metabolic process GO:0044255 323 0.075
regulation of cellular response to stress GO:0080135 159 0.074
granulocyte chemotaxis GO:0071621 39 0.073
Mouse
nitrogen compound transport GO:0071705 271 0.071
response to inorganic substance GO:0010035 96 0.070
leukotriene production involved in inflammatory response GO:0002540 2 0.070
leukocyte chemotaxis GO:0030595 69 0.068
Human Mouse
keratinocyte migration GO:0051546 3 0.067
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.066
apoptotic signaling pathway GO:0097190 306 0.065
Human
cation homeostasis GO:0055080 212 0.064
mature dendritic cell differentiation GO:0097029 3 0.064
regulation of mapk cascade GO:0043408 248 0.063
positive regulation of tumor necrosis factor production GO:0032760 30 0.062
Human
regulation of leukocyte mediated immunity GO:0002703 104 0.062
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.061
chemotaxis GO:0006935 247 0.059
Human Mouse
negative regulation of phospholipase activity GO:0010519 4 0.058
regulation of thymocyte migration GO:2000410 2 0.058
tumor necrosis factor production GO:0032640 50 0.058
Human
cellular chemical homeostasis GO:0055082 215 0.057
response to organonitrogen compound GO:0010243 246 0.057
positive regulation of secretion by cell GO:1903532 114 0.056
positive regulation of leukocyte mediated immunity GO:0002705 70 0.055
Mouse
cellular amine metabolic process GO:0044106 44 0.055
neutrophil chemotaxis GO:0030593 36 0.055
Mouse
hemostasis GO:0007599 78 0.053
Human
response to lipopolysaccharide GO:0032496 128 0.053
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.053
positive regulation of immune effector process GO:0002699 107 0.053
Mouse
cell recognition GO:0008037 83 0.052
striated muscle tissue development GO:0014706 293 0.052
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.052
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.051
Human
lipid biosynthetic process GO:0008610 179 0.050
calcium ion homeostasis GO:0055074 127 0.050
cell chemotaxis GO:0060326 81 0.050
Human Mouse
mitochondrial calcium ion homeostasis GO:0051560 7 0.050
regulation of cytokine secretion GO:0050707 61 0.050
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.049
immune response activating signal transduction GO:0002757 116 0.049
positive regulation of monocyte chemotaxis GO:0090026 2 0.048
cytokine production involved in immune response GO:0002367 34 0.048
negative regulation of cellular protein metabolic process GO:0032269 247 0.048
leukocyte migration GO:0050900 124 0.048
Human Mouse
cell killing GO:0001906 67 0.048
Mouse
positive regulation of programmed cell death GO:0043068 218 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.047
fatty acid biosynthetic process GO:0006633 41 0.047
regulation of protein secretion GO:0050708 82 0.047
lymphocyte differentiation GO:0030098 242 0.046
adaptive immune response GO:0002250 155 0.046
regulation of establishment of protein localization GO:0070201 181 0.045
innate immune response GO:0045087 157 0.045
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.044
negative regulation of cell proliferation GO:0008285 296 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.044
Human
cellular response to biotic stimulus GO:0071216 92 0.044
regulation of acute inflammatory response to non antigenic stimulus GO:0002877 2 0.043
regulation of jun kinase activity GO:0043506 40 0.043
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.043
regulation of vesicle mediated transport GO:0060627 139 0.043
positive regulation of defense response GO:0031349 124 0.043
Mouse
myeloid leukocyte migration GO:0097529 57 0.042
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.042
oxidation reduction process GO:0055114 342 0.041
organelle localization GO:0051640 179 0.041
regulation of endocytosis GO:0030100 69 0.041
detection of yeast GO:0001879 2 0.041
t cell mediated immunity GO:0002456 50 0.041
regulation of transferase activity GO:0051338 263 0.040
leukotriene biosynthetic process GO:0019370 5 0.040
response to oxidative stress GO:0006979 123 0.040
neutrophil migration GO:1990266 37 0.040
Mouse
regulation of binding GO:0051098 111 0.040
cellular calcium ion homeostasis GO:0006874 119 0.040
production of molecular mediator of immune response GO:0002440 103 0.039
purine nucleoside metabolic process GO:0042278 241 0.039
peptidyl amino acid modification GO:0018193 336 0.039
organophosphate biosynthetic process GO:0090407 122 0.038
regulation of t cell activation GO:0050863 170 0.038
organic anion transport GO:0015711 137 0.038
negative regulation of defense response GO:0031348 77 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
Human
homeostasis of number of cells GO:0048872 210 0.038
Mouse
icosanoid biosynthetic process GO:0046456 15 0.038
regulated secretory pathway GO:0045055 32 0.038
second messenger mediated signaling GO:0019932 73 0.037
Human
morphogenesis of a branching structure GO:0001763 203 0.037
cell junction maintenance GO:0034331 4 0.037
carbohydrate derivative biosynthetic process GO:1901137 183 0.037
positive regulation of acute inflammatory response to non antigenic stimulus GO:0002879 2 0.037
alpha beta t cell activation GO:0046631 91 0.036
response to acid chemical GO:0001101 111 0.036
regulation of inflammatory response GO:0050727 147 0.036
maintenance of location GO:0051235 89 0.036
regulation of reactive oxygen species metabolic process GO:2000377 40 0.036
Mouse
circulatory system process GO:0003013 197 0.036
cellular response to acid chemical GO:0071229 68 0.036
leukotriene metabolic process GO:0006691 7 0.036
regulation of cellular component biogenesis GO:0044087 181 0.035
myeloid leukocyte differentiation GO:0002573 119 0.035
Human
cation transport GO:0006812 399 0.035
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.035
Human
single organismal cell cell adhesion GO:0016337 131 0.035
t cell differentiation GO:0030217 174 0.034
regulation of anatomical structure size GO:0090066 178 0.034
small molecule biosynthetic process GO:0044283 132 0.034
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.034
regulation of cell adhesion GO:0030155 154 0.034
regulation of natural killer cell chemotaxis GO:2000501 1 0.034
regulation of leukocyte differentiation GO:1902105 159 0.034
Human
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.033
regulation of defense response GO:0031347 233 0.033
Mouse
positive regulation of eosinophil migration GO:2000418 2 0.033
activation of mapk activity GO:0000187 59 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
Human
activation of jun kinase activity GO:0007257 15 0.033
regulation of secretion by cell GO:1903530 249 0.033
myeloid cell differentiation GO:0030099 233 0.033
Human
acute inflammatory response GO:0002526 41 0.033
negative regulation of adaptive immune response GO:0002820 25 0.033
muscle tissue development GO:0060537 308 0.033
Mouse
regulation of hormone levels GO:0010817 211 0.033
exocytosis GO:0006887 121 0.033
anion transport GO:0006820 177 0.032
divalent inorganic cation homeostasis GO:0072507 138 0.032
gland development GO:0048732 330 0.032
positive regulation of protein modification process GO:0031401 299 0.032
regulation of kinase activity GO:0043549 249 0.032
regulation of cell motility GO:2000145 236 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
regulation of actin filament based process GO:0032970 99 0.032
activation of immune response GO:0002253 138 0.032
fc epsilon receptor signaling pathway GO:0038095 3 0.031
reactive oxygen species metabolic process GO:0072593 84 0.031
Mouse
negative regulation of inflammatory response GO:0050728 61 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
fatty acid derivative biosynthetic process GO:1901570 15 0.030
unsaturated fatty acid biosynthetic process GO:0006636 15 0.030
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.030
negative regulation of cellular component organization GO:0051129 194 0.030
Mouse
negative regulation of protein modification process GO:0031400 163 0.030
microtubule based process GO:0007017 236 0.030
positive regulation of phagocytosis GO:0050766 26 0.030
muscle cell development GO:0055001 133 0.030
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.030
cytosolic calcium ion homeostasis GO:0051480 70 0.029
positive regulation of cellular component biogenesis GO:0044089 94 0.029
regulation of protein transport GO:0051223 163 0.029
biomineral tissue development GO:0031214 64 0.029
epithelial tube morphogenesis GO:0060562 303 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.029
mitotic cell cycle GO:0000278 195 0.029
negative regulation of phagocytosis GO:0050765 4 0.029
eosinophil migration GO:0072677 3 0.029
regulation of organelle organization GO:0033043 289 0.028
cytoplasmic transport GO:0016482 234 0.028
muscle system process GO:0003012 141 0.028
defense response to gram negative bacterium GO:0050829 28 0.028
Mouse
transition metal ion homeostasis GO:0055076 54 0.028
carboxylic acid biosynthetic process GO:0046394 86 0.027
regulation of cytokine production involved in immune response GO:0002718 26 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.027
Human
ameboidal type cell migration GO:0001667 128 0.027
negative regulation of immune effector process GO:0002698 55 0.027
coagulation GO:0050817 78 0.026
Human
cellular response to hormone stimulus GO:0032870 150 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
regulation of homeostatic process GO:0032844 182 0.026
regulation of cell migration GO:0030334 219 0.026
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.026
protein oligomerization GO:0051259 67 0.026
phagocytosis recognition GO:0006910 12 0.026
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.026
muscle fiber development GO:0048747 76 0.025
Mouse
regulation of monocyte chemotaxis GO:0090025 3 0.025
reactive oxygen species biosynthetic process GO:1903409 8 0.025
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
leukocyte activation involved in immune response GO:0002366 126 0.025
organic hydroxy compound transport GO:0015850 93 0.025
regulation of lymphocyte mediated immunity GO:0002706 84 0.025
response to metal ion GO:0010038 47 0.025
regulation of cell cycle GO:0051726 281 0.025
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.025
regulation of ion transport GO:0043269 215 0.025
heterocycle catabolic process GO:0046700 280 0.024
lipid transport GO:0006869 98 0.024
positive regulation of hydrolase activity GO:0051345 148 0.024
regulation of blood coagulation GO:0030193 28 0.024
positive regulation of cell death GO:0010942 224 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
icosanoid metabolic process GO:0006690 33 0.024
regulation of synaptic plasticity GO:0048167 87 0.024
regulation of lymphocyte differentiation GO:0045619 107 0.024
positive regulation of leukocyte differentiation GO:1902107 86 0.024
Human
granulocyte macrophage colony stimulating factor biosynthetic process GO:0042253 2 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
peripheral nervous system axon regeneration GO:0014012 2 0.024
protein maturation GO:0051604 176 0.023
regulation of jnk cascade GO:0046328 62 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
macromolecule catabolic process GO:0009057 281 0.023
compound eye development GO:0048749 1 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.022
cdc42 protein signal transduction GO:0032488 0 0.022
thrombin receptor signaling pathway GO:0070493 2 0.022
divalent metal ion transport GO:0070838 172 0.022
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.022
negative regulation of molecular function GO:0044092 258 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
transmembrane transport GO:0055085 412 0.022
positive regulation of map kinase activity GO:0043406 84 0.022
vascular process in circulatory system GO:0003018 62 0.022
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.022
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.022
regulation of leukocyte proliferation GO:0070663 121 0.022
i kappab kinase nf kappab signaling GO:0007249 85 0.022
response to transforming growth factor beta GO:0071559 88 0.022
negative regulation of cell migration GO:0030336 59 0.022
positive regulation of intracellular transport GO:0032388 70 0.022
alpha beta t cell differentiation GO:0046632 69 0.022
lymphocyte proliferation GO:0046651 164 0.022
calcium ion transport GO:0006816 159 0.021
regulation of protein localization GO:0032880 231 0.021
anatomical structure homeostasis GO:0060249 145 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
cellular response to oxidative stress GO:0034599 76 0.021
organelle assembly GO:0070925 177 0.021
t helper 2 cell cytokine production GO:0035745 4 0.021
negative regulation of cytokine production GO:0001818 84 0.021
positive regulation of inflammatory response GO:0050729 47 0.021
regulation of tube size GO:0035150 57 0.021
negative regulation of lymphocyte proliferation GO:0050672 45 0.021
positive regulation of thymocyte migration GO:2000412 2 0.021
phagocytosis GO:0006909 66 0.021
regulation of t helper 2 cell cytokine production GO:2000551 3 0.021
peptidyl tyrosine modification GO:0018212 145 0.021
positive regulation of transferase activity GO:0051347 167 0.021
cell matrix adhesion GO:0007160 68 0.021
ossification GO:0001503 216 0.021
positive regulation of cytokine secretion GO:0050715 41 0.021
positive regulation of nervous system development GO:0051962 221 0.021
positive regulation of cell projection organization GO:0031346 95 0.020
neutrophil mediated immunity GO:0002446 19 0.020
Mouse
regulation of protein binding GO:0043393 60 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
dna metabolic process GO:0006259 303 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
Human
regulation of myeloid leukocyte differentiation GO:0002761 58 0.020
Human
regulation of phospholipase c activity GO:1900274 3 0.020
protein processing GO:0016485 163 0.020
positive regulation of response to wounding GO:1903036 66 0.020
leukocyte homeostasis GO:0001776 79 0.020
Mouse
cell type specific apoptotic process GO:0097285 268 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
negative regulation of cell activation GO:0050866 111 0.020
positive regulation of jun kinase activity GO:0043507 30 0.019
stress activated mapk cascade GO:0051403 80 0.019
dendritic cell dendrite assembly GO:0097026 2 0.019
cytosolic calcium ion transport GO:0060401 48 0.019
cellular response to lipid GO:0071396 145 0.019
antimicrobial peptide biosynthetic process GO:0002777 2 0.019
synaptic transmission GO:0007268 329 0.019
striated muscle cell development GO:0055002 125 0.019
Mouse
cell activation involved in immune response GO:0002263 126 0.019
regulation of production of molecular mediator of immune response GO:0002700 65 0.019
regulation of lymphocyte proliferation GO:0050670 117 0.019
positive regulation of vasoconstriction GO:0045907 4 0.019
male gamete generation GO:0048232 285 0.019
integrin mediated signaling pathway GO:0007229 27 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
Human
ion transmembrane transport GO:0034220 361 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
thymocyte migration GO:0072679 2 0.018
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.018
neuron death GO:0070997 154 0.018
stress activated protein kinase signaling cascade GO:0031098 81 0.018
protein secretion GO:0009306 111 0.018
interleukin 12 secretion GO:0072610 3 0.018
cellular response to lipopolysaccharide GO:0071222 77 0.018
negative regulation of lipoprotein lipase activity GO:0051005 1 0.018
detection of other organism GO:0098543 8 0.018
skeletal muscle organ development GO:0060538 163 0.018
Mouse
tube lumen cavitation GO:0060605 5 0.018
purine containing compound metabolic process GO:0072521 311 0.018
Human
tube formation GO:0035148 140 0.018
b cell mediated immunity GO:0019724 71 0.018
iron ion homeostasis GO:0055072 36 0.018
camera type eye development GO:0043010 266 0.018
divalent inorganic cation transport GO:0072511 178 0.018
nephron development GO:0072006 109 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
Human
protein modification by small protein conjugation or removal GO:0070647 207 0.018
organic acid biosynthetic process GO:0016053 86 0.018
astrocyte cell migration GO:0043615 3 0.018
cell substrate adhesion GO:0031589 130 0.018
immunoglobulin mediated immune response GO:0016064 69 0.018
positive regulation of synaptic plasticity GO:0031915 4 0.017
sequestering of metal ion GO:0051238 19 0.017
regulation of t cell mediated immunity GO:0002709 34 0.017
spermatogenesis GO:0007283 284 0.017
regulation of innate immune response GO:0045088 91 0.017
regulation of hydrolase activity GO:0051336 246 0.017
plasma membrane organization GO:0007009 90 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
regulation of interleukin 8 production GO:0032677 3 0.017
cellular response to inorganic substance GO:0071241 37 0.017
regulation of multi organism process GO:0043900 111 0.017
Mouse
regulation of fat cell differentiation GO:0045598 81 0.017
regionalization GO:0003002 337 0.017
positive regulation of epithelial cell proliferation GO:0050679 68 0.017
jnk cascade GO:0007254 72 0.017
smooth muscle contraction GO:0006939 44 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
extracellular structure organization GO:0043062 148 0.017
endomembrane system organization GO:0010256 147 0.017
multi multicellular organism process GO:0044706 109 0.017
regulation of b cell chemotaxis GO:2000537 2 0.017
cardiac muscle tissue development GO:0048738 130 0.017
positive regulation of chemokine production GO:0032722 22 0.017
regulation of erk1 and erk2 cascade GO:0070372 71 0.016
placenta development GO:0001890 140 0.016
regulation of alpha beta t cell differentiation GO:0046637 35 0.016
regulation of protein catabolic process GO:0042176 108 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
artery development GO:0060840 53 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
adiponectin secretion GO:0070162 2 0.016
regulation of removal of superoxide radicals GO:2000121 4 0.016
lymphocyte activation involved in immune response GO:0002285 93 0.016
regulation of ossification GO:0030278 112 0.016
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.016
regulation of t cell differentiation GO:0045580 83 0.016
aromatic compound catabolic process GO:0019439 286 0.016
carbohydrate homeostasis GO:0033500 128 0.016
glycoprotein metabolic process GO:0009100 116 0.016
regulation of blood pressure GO:0008217 93 0.016
telencephalon development GO:0021537 186 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
digestive tract development GO:0048565 190 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.016
regulation of mast cell activation GO:0033003 21 0.016
kidney development GO:0001822 213 0.016
serotonin secretion involved in inflammatory response GO:0002442 4 0.016
skeletal system morphogenesis GO:0048705 203 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
regulation of engulfment of apoptotic cell GO:1901074 2 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
t helper cell differentiation GO:0042093 28 0.016
negative regulation of lymphocyte activation GO:0051250 91 0.016
dendritic cell differentiation GO:0097028 26 0.016
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.016
organic acid transport GO:0015849 101 0.015
detection of biotic stimulus GO:0009595 10 0.015
lipid localization GO:0010876 126 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
Human
blood vessel morphogenesis GO:0048514 285 0.015
Human
regulation of mitotic cell cycle GO:0007346 126 0.015
bone mineralization GO:0030282 54 0.015
regulation of blood vessel size GO:0050880 56 0.015
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
negative regulation of map kinase activity GO:0043407 34 0.015
positive regulation of protein transport GO:0051222 93 0.015
regulation of system process GO:0044057 200 0.015
actin filament organization GO:0007015 113 0.015
release of sequestered calcium ion into cytosol GO:0051209 42 0.015
cellular response to interleukin 4 GO:0071353 21 0.015
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.015
fatty acid derivative metabolic process GO:1901568 33 0.015
sensory perception GO:0007600 245 0.015
regulation of nuclear division GO:0051783 56 0.015
nucleoside metabolic process GO:0009116 246 0.015
regulation of cellular component size GO:0032535 121 0.015
leukocyte apoptotic process GO:0071887 71 0.015
regulation of ion homeostasis GO:2000021 64 0.015
epithelial cell proliferation GO:0050673 174 0.015
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.015
nucleoside catabolic process GO:0009164 206 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
negative regulation of cell cycle GO:0045786 123 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.015
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.015
Mouse
negative regulation of phosphorylation GO:0042326 166 0.015
myeloid cell homeostasis GO:0002262 114 0.015
neuron apoptotic process GO:0051402 142 0.015
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.015
protein catabolic process GO:0030163 221 0.015
regulation of rho protein signal transduction GO:0035023 71 0.014
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.014
regulation of neural retina development GO:0061074 3 0.014
development of primary sexual characteristics GO:0045137 143 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
glomerular mesangial cell proliferation GO:0072110 3 0.014
positive regulation of organelle organization GO:0010638 128 0.014
positive regulation of cell development GO:0010720 237 0.014
disruption by host of symbiont cells GO:0051852 11 0.014
Mouse
sequestering of calcium ion GO:0051208 18 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
regulation of b cell mediated immunity GO:0002712 37 0.014
positive regulation of lymphocyte differentiation GO:0045621 61 0.014
cytokine metabolic process GO:0042107 71 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
b cell chemotaxis GO:0035754 3 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
organophosphate catabolic process GO:0046434 232 0.014
negative regulation of leukocyte proliferation GO:0070664 46 0.014
positive regulation of protein secretion GO:0050714 52 0.014
sensory organ morphogenesis GO:0090596 242 0.014
gonad development GO:0008406 141 0.014
endocytosis GO:0006897 168 0.014
regulation of cell projection assembly GO:0060491 38 0.014
regulation of immunoglobulin mediated immune response GO:0002889 37 0.014
cellular response to peptide GO:1901653 92 0.014
regulation of exit from mitosis GO:0007096 1 0.014
leukocyte mediated cytotoxicity GO:0001909 62 0.014
Mouse
homotypic cell cell adhesion GO:0034109 28 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
hormone metabolic process GO:0042445 86 0.014

Pf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
blood coagulation disease DOID:1247 0 0.261
inherited blood coagulation disease DOID:2214 0 0.261
hematopoietic system disease DOID:74 0 0.261
disease of anatomical entity DOID:7 0 0.261
immune system disease DOID:2914 0 0.261
musculoskeletal system disease DOID:17 0 0.067
connective tissue disease DOID:65 0 0.067
disease by infectious agent DOID:0050117 0 0.015
inherited metabolic disorder DOID:655 0 0.015
disease of metabolism DOID:0014667 0 0.015