Mus musculus

91 known processes

Pfkl

phosphofructokinase, liver, B-type

(Aliases: AA407869)

Pfkl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate catabolic process GO:0016052 32 0.981
glycolytic process GO:0006096 20 0.922
pyruvate metabolic process GO:0006090 28 0.785
monocarboxylic acid metabolic process GO:0032787 191 0.752
nucleobase containing small molecule metabolic process GO:0055086 352 0.710
carbohydrate metabolic process GO:0005975 230 0.687
nucleoside triphosphate metabolic process GO:0009141 230 0.550
hexose catabolic process GO:0019320 3 0.543
synaptic transmission GO:0007268 329 0.501
carbohydrate derivative biosynthetic process GO:1901137 183 0.421
myosin filament organization GO:0031033 3 0.340
purine containing compound metabolic process GO:0072521 311 0.319
nucleoside metabolic process GO:0009116 246 0.302
skin development GO:0043588 220 0.295
nucleotide metabolic process GO:0009117 332 0.290
nucleoside phosphate metabolic process GO:0006753 338 0.288
purine ribonucleotide metabolic process GO:0009150 290 0.262
muscle system process GO:0003012 141 0.242
hexose metabolic process GO:0019318 98 0.239
sperm motility GO:0030317 47 0.233
regulation of homeostatic process GO:0032844 182 0.231
purine nucleoside metabolic process GO:0042278 241 0.230
atp metabolic process GO:0046034 75 0.226
nucleoside monophosphate metabolic process GO:0009123 85 0.218
glucose homeostasis GO:0042593 128 0.216
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.209
membrane organization GO:0061024 245 0.205
purine nucleotide metabolic process GO:0006163 302 0.202
ribose phosphate metabolic process GO:0019693 291 0.201
organophosphate catabolic process GO:0046434 232 0.194
cellular homeostasis GO:0019725 240 0.194
cytoplasmic transport GO:0016482 234 0.191
nucleoside triphosphate catabolic process GO:0009143 205 0.185
ribonucleoside monophosphate metabolic process GO:0009161 80 0.182
oxidation reduction process GO:0055114 342 0.176
cellular amine metabolic process GO:0044106 44 0.175
intracellular protein transport GO:0006886 204 0.173
cellular amino acid metabolic process GO:0006520 103 0.168
negative regulation of cellular protein metabolic process GO:0032269 247 0.165
transmembrane transport GO:0055085 412 0.163
mitotic cell cycle GO:0000278 195 0.157
monosaccharide metabolic process GO:0005996 106 0.153
nucleoside phosphate biosynthetic process GO:1901293 79 0.146
generation of precursor metabolites and energy GO:0006091 103 0.146
purine ribonucleoside metabolic process GO:0046128 241 0.145
mitochondrion organization GO:0007005 134 0.145
ribonucleoside triphosphate metabolic process GO:0009199 220 0.143
protein localization to organelle GO:0033365 185 0.140
striated muscle myosin thick filament assembly GO:0071688 1 0.136
protein targeting GO:0006605 143 0.132
muscle cell development GO:0055001 133 0.131
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.131
cellular ketone metabolic process GO:0042180 84 0.129
purine nucleotide biosynthetic process GO:0006164 65 0.128
ion transmembrane transport GO:0034220 361 0.127
pentose phosphate shunt GO:0006098 2 0.125
protein processing GO:0016485 163 0.124
nadph regeneration GO:0006740 2 0.122
anatomical structure homeostasis GO:0060249 145 0.121
nitrogen compound transport GO:0071705 271 0.118
striated muscle contraction GO:0006941 45 0.117
cellular lipid metabolic process GO:0044255 323 0.116
maintenance of location GO:0051235 89 0.115
regulation of synaptic plasticity GO:0048167 87 0.114
carbohydrate homeostasis GO:0033500 128 0.112
Mouse
ribonucleotide metabolic process GO:0009259 291 0.112
response to organic cyclic compound GO:0014070 198 0.111
embryonic placenta development GO:0001892 98 0.111
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.107
myosin filament assembly GO:0031034 2 0.105
glucose catabolic process GO:0006007 3 0.102
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.101
homeostasis of number of cells GO:0048872 210 0.100
amine metabolic process GO:0009308 45 0.099
regulation of cellular amino acid metabolic process GO:0006521 5 0.099
cellular carbohydrate metabolic process GO:0044262 119 0.097
response to heat GO:0009408 27 0.097
purine nucleoside triphosphate metabolic process GO:0009144 226 0.096
cellular response to cadmium ion GO:0071276 3 0.095
response to oxidative stress GO:0006979 123 0.094
metal ion homeostasis GO:0055065 189 0.094
purine nucleoside triphosphate catabolic process GO:0009146 203 0.091
regulation of cell projection organization GO:0031344 206 0.090
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.088
organic anion transport GO:0015711 137 0.088
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.088
purine nucleoside monophosphate biosynthetic process GO:0009127 9 0.087
regulation of cellular amine metabolic process GO:0033238 20 0.086
regulation of hormone levels GO:0010817 211 0.086
ribose phosphate biosynthetic process GO:0046390 59 0.084
aromatic compound catabolic process GO:0019439 286 0.084
cation transport GO:0006812 399 0.083
establishment of protein localization to organelle GO:0072594 118 0.083
anion transport GO:0006820 177 0.083
response to decreased oxygen levels GO:0036293 59 0.082
insulin secretion GO:0030073 89 0.082
regulation of peptide transport GO:0090087 91 0.081
heterocycle catabolic process GO:0046700 280 0.081
axonogenesis GO:0007409 274 0.080
fatty acid metabolic process GO:0006631 121 0.080
modification dependent protein catabolic process GO:0019941 133 0.078
purine ribonucleotide catabolic process GO:0009154 208 0.078
muscle cell differentiation GO:0042692 261 0.076
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.076
organonitrogen compound catabolic process GO:1901565 264 0.076
ribonucleoside metabolic process GO:0009119 245 0.076
purine nucleoside biosynthetic process GO:0042451 19 0.075
glucose metabolic process GO:0006006 92 0.073
ribonucleotide biosynthetic process GO:0009260 59 0.072
cellular response to extracellular stimulus GO:0031668 81 0.070
purine nucleoside monophosphate metabolic process GO:0009126 81 0.070
cellular response to external stimulus GO:0071496 88 0.069
g protein coupled receptor signaling pathway GO:0007186 243 0.069
divalent inorganic cation homeostasis GO:0072507 138 0.068
positive regulation of cellular amine metabolic process GO:0033240 5 0.067
organic acid transport GO:0015849 101 0.066
protein catabolic process GO:0030163 221 0.066
regulation of cell cycle GO:0051726 281 0.066
regulation of neuron differentiation GO:0045664 281 0.066
response to lipopolysaccharide GO:0032496 128 0.065
cellular ion homeostasis GO:0006873 165 0.065
regulation of protein localization GO:0032880 231 0.065
positive regulation of apoptotic process GO:0043065 217 0.064
purine ribonucleoside catabolic process GO:0046130 205 0.064
sensory perception GO:0007600 245 0.064
ras protein signal transduction GO:0007265 77 0.064
divalent metal ion transport GO:0070838 172 0.063
organelle assembly GO:0070925 177 0.063
regulation of translation GO:0006417 71 0.062
response to extracellular stimulus GO:0009991 127 0.061
single organism nuclear import GO:1902593 95 0.061
purine containing compound catabolic process GO:0072523 213 0.060
protein modification by small protein conjugation GO:0032446 187 0.059
response to oxygen levels GO:0070482 62 0.059
ribonucleoside catabolic process GO:0042454 206 0.059
myofibril assembly GO:0030239 34 0.059
cellular divalent inorganic cation homeostasis GO:0072503 127 0.059
hormone secretion GO:0046879 128 0.059
negative regulation of molecular function GO:0044092 258 0.058
response to nutrient levels GO:0031667 109 0.057
cognition GO:0050890 149 0.057
muscle contraction GO:0006936 101 0.056
purine nucleoside catabolic process GO:0006152 205 0.056
peptide transport GO:0015833 133 0.056
cell type specific apoptotic process GO:0097285 268 0.056
negative regulation of neuron death GO:1901215 98 0.056
nucleotide catabolic process GO:0009166 217 0.055
single organismal cell cell adhesion GO:0016337 131 0.055
regulation of secretion by cell GO:1903530 249 0.055
protein maturation GO:0051604 176 0.055
immune response regulating signaling pathway GO:0002764 125 0.054
blood vessel morphogenesis GO:0048514 285 0.054
oocyte axis specification GO:0007309 2 0.054
small gtpase mediated signal transduction GO:0007264 97 0.054
leukocyte differentiation GO:0002521 342 0.054
nucleoside phosphate catabolic process GO:1901292 222 0.053
histone modification GO:0016570 159 0.053
calcium ion transport GO:0006816 159 0.053
protein oligomerization GO:0051259 67 0.053
Human Rat
lipid localization GO:0010876 126 0.053
learning or memory GO:0007611 148 0.052
positive regulation of mapk cascade GO:0043410 170 0.052
chemotaxis GO:0006935 247 0.052
oocyte construction GO:0007308 2 0.052
ribonucleoside triphosphate catabolic process GO:0009203 199 0.051
dephosphorylation GO:0016311 129 0.050
actomyosin structure organization GO:0031032 56 0.050
peptidyl amino acid modification GO:0018193 336 0.050
response to inorganic substance GO:0010035 96 0.050
regulation of metal ion transport GO:0010959 106 0.049
epidermis development GO:0008544 187 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.049
positive regulation of ion transport GO:0043270 65 0.049
regulation of cell motility GO:2000145 236 0.048
multicellular organism growth GO:0035264 161 0.048
purine ribonucleotide biosynthetic process GO:0009152 59 0.047
placenta development GO:0001890 140 0.047
photoreceptor cell differentiation GO:0046530 52 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.046
negative regulation of protein metabolic process GO:0051248 282 0.046
multi organism behavior GO:0051705 62 0.046
cellular response to growth factor stimulus GO:0071363 197 0.046
regulation of ion transport GO:0043269 215 0.046
positive regulation of organelle organization GO:0010638 128 0.046
mitotic cell cycle checkpoint GO:0007093 31 0.045
peptidyl proline hydroxylation GO:0019511 3 0.044
sequestering of calcium ion GO:0051208 18 0.044
purine nucleotide catabolic process GO:0006195 211 0.044
lung development GO:0030324 164 0.043
regionalization GO:0003002 337 0.043
positive regulation of protein phosphorylation GO:0001934 242 0.043
cellular response to nutrient levels GO:0031669 64 0.042
positive regulation of cell development GO:0010720 237 0.041
response to reactive oxygen species GO:0000302 56 0.041
multi multicellular organism process GO:0044706 109 0.041
cation homeostasis GO:0055080 212 0.041
response to starvation GO:0042594 65 0.041
organic hydroxy compound metabolic process GO:1901615 203 0.040
regulation of secretion GO:0051046 274 0.040
amide transport GO:0042886 138 0.040
neuron apoptotic process GO:0051402 142 0.040
positive regulation of growth GO:0045927 104 0.040
regulation of proteolysis GO:0030162 164 0.039
calcium ion homeostasis GO:0055074 127 0.039
nucleotide biosynthetic process GO:0009165 78 0.039
regulation of cellular catabolic process GO:0031329 242 0.039
response to temperature stimulus GO:0009266 55 0.039
cellular component assembly involved in morphogenesis GO:0010927 139 0.039
steroid metabolic process GO:0008202 119 0.039
striated muscle cell development GO:0055002 125 0.039
response to acid chemical GO:0001101 111 0.038
positive regulation of protein modification process GO:0031401 299 0.038
cellular aldehyde metabolic process GO:0006081 12 0.038
leukocyte proliferation GO:0070661 172 0.038
nuclear import GO:0051170 95 0.038
establishment of organelle localization GO:0051656 122 0.038
vesicle localization GO:0051648 86 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
divalent inorganic cation transport GO:0072511 178 0.037
sequestering of metal ion GO:0051238 19 0.037
protein localization to nucleus GO:0034504 121 0.037
alcohol metabolic process GO:0006066 116 0.036
neuronal action potential GO:0019228 54 0.036
sodium ion transport GO:0006814 73 0.036
response to monosaccharide GO:0034284 67 0.036
protein import into nucleus GO:0006606 95 0.036
epithelial cell proliferation GO:0050673 174 0.036
organophosphate biosynthetic process GO:0090407 122 0.036
central nervous system neuron differentiation GO:0021953 162 0.035
formation of primary germ layer GO:0001704 77 0.035
blood circulation GO:0008015 195 0.035
regulation of neuron death GO:1901214 134 0.035
reproductive behavior GO:0019098 32 0.035
regulation of establishment of protein localization GO:0070201 181 0.035
peptide hormone secretion GO:0030072 109 0.035
energy derivation by oxidation of organic compounds GO:0015980 77 0.035
pigmentation GO:0043473 71 0.035
compound eye development GO:0048749 1 0.034
regulation of nucleotide metabolic process GO:0006140 169 0.034
regulation of response to wounding GO:1903034 189 0.034
labyrinthine layer development GO:0060711 49 0.034
telencephalon development GO:0021537 186 0.033
protein import GO:0017038 101 0.033
protein localization to membrane GO:0072657 108 0.033
response to epidermal growth factor GO:0070849 4 0.033
purine ribonucleoside biosynthetic process GO:0046129 19 0.033
nucleoside catabolic process GO:0009164 206 0.033
cellular metal ion homeostasis GO:0006875 151 0.033
multicellular organismal reproductive behavior GO:0033057 23 0.033
positive regulation of cell death GO:0010942 224 0.032
response to peptide GO:1901652 136 0.032
glycosyl compound catabolic process GO:1901658 206 0.032
organic hydroxy compound biosynthetic process GO:1901617 77 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
response to molecule of bacterial origin GO:0002237 143 0.032
leukocyte homeostasis GO:0001776 79 0.032
cytosolic calcium ion homeostasis GO:0051480 70 0.032
mapk cascade GO:0000165 281 0.032
apoptotic signaling pathway GO:0097190 306 0.032
multicellular organismal signaling GO:0035637 91 0.032
regulation of cytoplasmic transport GO:1903649 112 0.031
nuclear transport GO:0051169 139 0.031
camera type eye development GO:0043010 266 0.031
mesoderm development GO:0007498 100 0.031
response to organonitrogen compound GO:0010243 246 0.031
skeletal system development GO:0001501 356 0.031
carbohydrate biosynthetic process GO:0016051 74 0.031
peptidyl tyrosine modification GO:0018212 145 0.031
mesoderm formation GO:0001707 62 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.030
regulation of hydrolase activity GO:0051336 246 0.030
lipid homeostasis GO:0055088 63 0.030
atp catabolic process GO:0006200 55 0.030
regulation of lipid metabolic process GO:0019216 118 0.030
positive regulation of response to wounding GO:1903036 66 0.030
rhythmic process GO:0048511 174 0.030
response to radiation GO:0009314 165 0.030
tissue migration GO:0090130 68 0.029
neuromuscular process GO:0050905 99 0.029
carboxylic acid biosynthetic process GO:0046394 86 0.029
polysaccharide metabolic process GO:0005976 39 0.029
cellular response to cytokine stimulus GO:0071345 189 0.029
wound healing GO:0042060 157 0.029
establishment of vesicle localization GO:0051650 81 0.029
response to light stimulus GO:0009416 135 0.029
cellular chemical homeostasis GO:0055082 215 0.029
response to hypoxia GO:0001666 58 0.029
cellular protein complex assembly GO:0043623 116 0.029
positive regulation of intracellular transport GO:0032388 70 0.029
myotube differentiation GO:0014902 105 0.028
regulation of system process GO:0044057 200 0.028
heart contraction GO:0060047 93 0.028
synaptic vesicle localization GO:0097479 59 0.028
tissue homeostasis GO:0001894 115 0.028
actin filament polymerization GO:0030041 44 0.028
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.028
hexose transport GO:0008645 56 0.028
negative regulation of synapse assembly GO:0051964 3 0.028
regulation of intracellular transport GO:0032386 159 0.028
somitogenesis GO:0001756 69 0.028
cellular modified amino acid metabolic process GO:0006575 63 0.027
positive regulation of neuron projection development GO:0010976 79 0.027
cellular response to acid chemical GO:0071229 68 0.027
neuron neuron synaptic transmission GO:0007270 69 0.027
cell maturation GO:0048469 127 0.027
gland development GO:0048732 330 0.027
cellular carbohydrate catabolic process GO:0044275 15 0.027
rho protein signal transduction GO:0007266 32 0.027
positive regulation of secretion GO:0051047 130 0.026
Mouse
single organism cell adhesion GO:0098602 156 0.026
regulation of erk1 and erk2 cascade GO:0070372 71 0.026
multicellular organismal aging GO:0010259 24 0.026
response to steroid hormone GO:0048545 56 0.026
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.026
eye photoreceptor cell differentiation GO:0001754 41 0.026
peptidyl tyrosine phosphorylation GO:0018108 143 0.026
reactive nitrogen species metabolic process GO:2001057 0 0.026
translation GO:0006412 93 0.026
circulatory system process GO:0003013 197 0.026
glycoprotein biosynthetic process GO:0009101 89 0.026
placenta blood vessel development GO:0060674 31 0.025
glycerolipid metabolic process GO:0046486 122 0.025
negative regulation of neuron apoptotic process GO:0043524 92 0.025
cellular calcium ion homeostasis GO:0006874 119 0.025
regulation of ion transmembrane transport GO:0034765 119 0.025
proteasomal protein catabolic process GO:0010498 98 0.025
male gamete generation GO:0048232 285 0.025
regulation of body fluid levels GO:0050878 162 0.025
regulation of neuron apoptotic process GO:0043523 122 0.025
regulation of t cell activation GO:0050863 170 0.025
oocyte anterior posterior axis specification GO:0007314 2 0.025
epithelial cell migration GO:0010631 63 0.025
endomembrane system organization GO:0010256 147 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
regulation of neuron projection development GO:0010975 169 0.025
lactate biosynthetic process GO:0019249 4 0.024
smoothened signaling pathway GO:0007224 105 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
locomotory behavior GO:0007626 195 0.024
t cell activation GO:0042110 289 0.024
apoptotic mitochondrial changes GO:0008637 48 0.024
regulation of calcium ion transport GO:0051924 69 0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.024
germ cell development GO:0007281 185 0.024
learning GO:0007612 98 0.024
muscle cell cellular homeostasis GO:0046716 12 0.024
synapse assembly GO:0007416 56 0.024
fertilization GO:0009566 127 0.024
macroautophagy GO:0016236 21 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
skeletal system morphogenesis GO:0048705 203 0.023
regulation of organelle organization GO:0033043 289 0.023
protein localization to plasma membrane GO:0072659 57 0.023
regulation of cell shape GO:0008360 39 0.023
associative learning GO:0008306 61 0.023
regulation of glucose metabolic process GO:0010906 60 0.023
positive regulation of cell motility GO:2000147 116 0.023
sensory organ morphogenesis GO:0090596 242 0.023
fat cell differentiation GO:0045444 160 0.023
positive regulation of interleukin 13 secretion GO:2000667 1 0.023
sulfur compound metabolic process GO:0006790 100 0.023
macromolecule catabolic process GO:0009057 281 0.023
nucleoside monophosphate catabolic process GO:0009125 59 0.023
blood coagulation GO:0007596 76 0.023
vesicle organization GO:0016050 60 0.023
regulation of t cell proliferation GO:0042129 92 0.023
digestive tract morphogenesis GO:0048546 147 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
regulation of cysteine type endopeptidase activity GO:2000116 65 0.023
circadian rhythm GO:0007623 114 0.023
lymphocyte proliferation GO:0046651 164 0.023
developmental maturation GO:0021700 193 0.023
cellular response to hormone stimulus GO:0032870 150 0.023
regulation of leukocyte proliferation GO:0070663 121 0.023
cholesterol metabolic process GO:0008203 56 0.023
nucleocytoplasmic transport GO:0006913 139 0.022
endocytosis GO:0006897 168 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.022
synaptic vesicle transport GO:0048489 57 0.022
positive regulation of interleukin 5 secretion GO:2000664 1 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
negative regulation of response to wounding GO:1903035 77 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
Mouse
positive regulation of kinase activity GO:0033674 155 0.022
meiotic cell cycle GO:0051321 122 0.022
conditioned taste aversion GO:0001661 4 0.022
respiratory system development GO:0060541 190 0.022
nucleoside biosynthetic process GO:0009163 21 0.022
synapse organization GO:0050808 125 0.022
positive regulation of nervous system development GO:0051962 221 0.022
mitotic cell cycle process GO:1903047 159 0.022
positive regulation of peptide hormone secretion GO:0090277 31 0.021
Mouse
carboxylic acid transport GO:0046942 100 0.021
glucan metabolic process GO:0044042 32 0.021
actin polymerization or depolymerization GO:0008154 54 0.021
epithelium migration GO:0090132 63 0.021
cellular response to lipid GO:0071396 145 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
protein complex disassembly GO:0043241 40 0.021
regulation of transposition GO:0010528 2 0.021
eye photoreceptor cell development GO:0042462 31 0.021
regulation of peptidase activity GO:0052547 96 0.021
habituation GO:0046959 3 0.021
ribonucleoside biosynthetic process GO:0042455 21 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
mesoderm morphogenesis GO:0048332 64 0.021
transmission of nerve impulse GO:0019226 76 0.021
memory GO:0007613 58 0.021
pyridine nucleotide metabolic process GO:0019362 12 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
regulation of cell cycle phase transition GO:1901987 77 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
cyclic nucleotide metabolic process GO:0009187 59 0.020
monocarboxylic acid transport GO:0015718 44 0.020
negative regulation of apoptotic signaling pathway GO:2001234 104 0.020
negative regulation of cell projection organization GO:0031345 56 0.020
cerebellar purkinje cell layer development GO:0021680 26 0.020
t helper 2 cell activation GO:0035712 2 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.020
hormone metabolic process GO:0042445 86 0.020
substantia nigra development GO:0021762 2 0.020
regulation of hormone secretion GO:0046883 88 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
glycoprotein metabolic process GO:0009100 116 0.020
response to alkaloid GO:0043279 34 0.020
chromatin modification GO:0016568 187 0.020
regulation of cell migration GO:0030334 219 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.020
glucose transport GO:0015758 56 0.019
negative regulation of homeostatic process GO:0032845 71 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
alpha amino acid metabolic process GO:1901605 59 0.019
actin cytoskeleton organization GO:0030036 220 0.019
oxidoreduction coenzyme metabolic process GO:0006733 16 0.019
negative regulation of transposition GO:0010529 2 0.019
respiratory tube development GO:0030323 167 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
regulation of cell cycle process GO:0010564 160 0.019
segmentation GO:0035282 93 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.019
cytokine production GO:0001816 319 0.019
regulation of protein kinase activity GO:0045859 232 0.019
spermatogenesis GO:0007283 284 0.019
gonad development GO:0008406 141 0.019
negative regulation of nervous system development GO:0051961 156 0.018
immune response activating signal transduction GO:0002757 116 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.018
release of sequestered calcium ion into cytosol GO:0051209 42 0.018
carbohydrate transport GO:0008643 62 0.018
energy reserve metabolic process GO:0006112 39 0.018
regulation of ral protein signal transduction GO:0032485 4 0.018
activation of adenylate cyclase activity GO:0007190 4 0.018
anion transmembrane transport GO:0098656 71 0.018
neuron migration GO:0001764 122 0.018
negative regulation of protein maturation GO:1903318 79 0.018
retina development in camera type eye GO:0060041 119 0.018
cell junction maintenance GO:0034331 4 0.018
gtp catabolic process GO:0006184 143 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
negative regulation of protein modification process GO:0031400 163 0.018
regulation of ion homeostasis GO:2000021 64 0.018
cellular response to parathyroid hormone stimulus GO:0071374 2 0.018
cellular response to lipopolysaccharide GO:0071222 77 0.018
organic acid catabolic process GO:0016054 51 0.018
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
cytosolic calcium ion transport GO:0060401 48 0.017
regulation of neuronal synaptic plasticity GO:0048168 30 0.017
ameboidal type cell migration GO:0001667 128 0.017
t cell proliferation GO:0042098 120 0.017
fatty acid transmembrane transport GO:1902001 1 0.017
regulation of ral gtpase activity GO:0032315 4 0.017
digestive tract development GO:0048565 190 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
cell growth GO:0016049 130 0.017
leukocyte migration GO:0050900 124 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
development of primary sexual characteristics GO:0045137 143 0.017
regulation of lymphocyte proliferation GO:0050670 117 0.017
regulation of cell activation GO:0050865 289 0.017
cellular protein complex disassembly GO:0043624 36 0.017
molting cycle GO:0042303 90 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
sensory system development GO:0048880 3 0.017
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.017

Pfkl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.225
disease of anatomical entity DOID:7 0 0.167
nervous system disease DOID:863 0 0.167
central nervous system disease DOID:331 0 0.079
immune system disease DOID:2914 0 0.037