Mus musculus

181 known processes

Pfn2

profilin 2

(Aliases: Pfn)

Pfn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of actin filament length GO:0030832 45 0.825
regulation of actin nucleation GO:0051125 4 0.756
regulation of actin filament polymerization GO:0030833 38 0.729
olfactory learning GO:0008355 2 0.669
positive regulation of actin filament polymerization GO:0030838 26 0.643
positive regulation of actin nucleation GO:0051127 3 0.626
actin polymerization or depolymerization GO:0008154 54 0.615
actin filament polymerization GO:0030041 44 0.533
protein polymerization GO:0051258 57 0.455
positive regulation of protein complex assembly GO:0031334 45 0.454
positive regulation of cellular component biogenesis GO:0044089 94 0.453
positive regulation of cytoskeleton organization GO:0051495 49 0.449
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.420
regulation of actin cytoskeleton organization GO:0032956 84 0.392
positive regulation of necrotic cell death GO:0010940 1 0.310
cell junction maintenance GO:0034331 4 0.280
synapse organization GO:0050808 125 0.274
positive regulation of organelle organization GO:0010638 128 0.251
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.237
actin cytoskeleton organization GO:0030036 220 0.218
neural tube development GO:0021915 160 0.213
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.207
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.202
rac protein signal transduction GO:0016601 13 0.198
purine nucleotide metabolic process GO:0006163 302 0.191
Human
establishment of vesicle localization GO:0051650 81 0.167
regulation of actin polymerization or depolymerization GO:0008064 45 0.161
endosome organization GO:0007032 9 0.161
purine ribonucleotide metabolic process GO:0009150 290 0.159
Human
lamellipodium organization GO:0097581 29 0.159
sperm individualization GO:0007291 1 0.155
cilium morphogenesis GO:0060271 102 0.152
regulation of cell projection organization GO:0031344 206 0.151
regulation of cellular component biogenesis GO:0044087 181 0.151
arp2 3 complex mediated actin nucleation GO:0034314 3 0.149
small gtpase mediated signal transduction GO:0007264 97 0.128
cellularization GO:0007349 1 0.124
regulation of organelle organization GO:0033043 289 0.123
cellular protein complex assembly GO:0043623 116 0.123
regulation of protein localization GO:0032880 231 0.117
positive regulation of cell projection organization GO:0031346 95 0.116
protein localization to organelle GO:0033365 185 0.113
intracellular protein transport GO:0006886 204 0.109
spermatid differentiation GO:0048515 115 0.107
neuron projection guidance GO:0097485 141 0.107
regulation of actin filament based process GO:0032970 99 0.104
ribonucleoside metabolic process GO:0009119 245 0.101
Human
spermatid development GO:0007286 108 0.100
purine containing compound metabolic process GO:0072521 311 0.099
Human
purine nucleotide catabolic process GO:0006195 211 0.096
Human
regulation of lamellipodium assembly GO:0010591 3 0.096
negative regulation of synapse assembly GO:0051964 3 0.096
regulation of cell activation GO:0050865 289 0.094
cellular response to dna damage stimulus GO:0006974 207 0.094
embryonic epithelial tube formation GO:0001838 130 0.094
Mouse
synaptic vesicle localization GO:0097479 59 0.091
spermatogenesis GO:0007283 284 0.091
carbohydrate derivative catabolic process GO:1901136 231 0.089
Human
regulation of kinase activity GO:0043549 249 0.088
primary neural tube formation GO:0014020 95 0.087
Mouse
ribonucleotide metabolic process GO:0009259 291 0.085
Human
conditioned taste aversion GO:0001661 4 0.084
ribonucleoside triphosphate metabolic process GO:0009199 220 0.080
Human
neuron migration GO:0001764 122 0.078
organelle assembly GO:0070925 177 0.078
regulation of establishment of protein localization GO:0070201 181 0.075
actin filament based movement GO:0030048 23 0.074
synaptic transmission GO:0007268 329 0.074
membrane organization GO:0061024 245 0.072
ribonucleotide catabolic process GO:0009261 208 0.071
Human
ribose phosphate metabolic process GO:0019693 291 0.071
Human
endomembrane system organization GO:0010256 147 0.071
adherens junction maintenance GO:0034334 1 0.070
nucleoside metabolic process GO:0009116 246 0.067
Human
myotube differentiation GO:0014902 105 0.066
microtubule severing GO:0051013 5 0.066
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.066
glycosyl compound metabolic process GO:1901657 246 0.065
Human
nucleoside catabolic process GO:0009164 206 0.065
Human
notch signaling pathway GO:0007219 71 0.064
aromatic compound catabolic process GO:0019439 286 0.064
Human
mitochondrion organization GO:0007005 134 0.063
ribonucleoside triphosphate catabolic process GO:0009203 199 0.061
Human
chemotaxis GO:0006935 247 0.061
protein catabolic process GO:0030163 221 0.060
neural tube closure GO:0001843 90 0.060
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.060
regulation of protein transport GO:0051223 163 0.059
regionalization GO:0003002 337 0.059
neural tube formation GO:0001841 108 0.059
Mouse
regulation of cell motility GO:2000145 236 0.058
negative regulation of protein metabolic process GO:0051248 282 0.058
morphogenesis of embryonic epithelium GO:0016331 159 0.056
Mouse
smoothened signaling pathway GO:0007224 105 0.056
ubiquitin dependent protein catabolic process GO:0006511 129 0.056
compound eye development GO:0048749 1 0.056
pole plasm assembly GO:0007315 2 0.056
male gamete generation GO:0048232 285 0.056
regulation of vesicle mediated transport GO:0060627 139 0.055
positive regulation of nervous system development GO:0051962 221 0.055
protein lipidation GO:0006497 28 0.053
glycosyl compound catabolic process GO:1901658 206 0.053
Human
regulation of anatomical structure size GO:0090066 178 0.053
regulation of membrane potential GO:0042391 192 0.052
purine ribonucleoside metabolic process GO:0046128 241 0.051
Human
negative regulation of cellular component organization GO:0051129 194 0.051
cellular protein catabolic process GO:0044257 155 0.051
synaptic vesicle membrane organization GO:0048499 1 0.050
nucleotide catabolic process GO:0009166 217 0.050
Human
transmembrane transport GO:0055085 412 0.049
gtp metabolic process GO:0046039 144 0.049
establishment of protein localization to organelle GO:0072594 118 0.049
protein modification by small protein conjugation GO:0032446 187 0.048
guanosine containing compound metabolic process GO:1901068 144 0.048
clathrin mediated endocytosis GO:0072583 7 0.048
cellular component assembly involved in morphogenesis GO:0010927 139 0.048
myelination GO:0042552 74 0.047
development of primary sexual characteristics GO:0045137 143 0.047
t cell proliferation GO:0042098 120 0.047
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.046
myeloid cell differentiation GO:0030099 233 0.046
proteasomal protein catabolic process GO:0010498 98 0.045
cell division GO:0051301 120 0.045
vesicle localization GO:0051648 86 0.044
gland development GO:0048732 330 0.044
organic cyclic compound catabolic process GO:1901361 295 0.043
Human
behavioral response to nutrient GO:0051780 1 0.043
dorsal ventral axon guidance GO:0033563 3 0.043
purine containing compound catabolic process GO:0072523 213 0.043
Human
protein targeting GO:0006605 143 0.042
toxin transport GO:1901998 38 0.042
renal system development GO:0072001 225 0.042
neurotransmitter transport GO:0006836 76 0.041
purine nucleoside catabolic process GO:0006152 205 0.041
Human
negative regulation of inclusion body assembly GO:0090084 1 0.041
negative regulation of protein transport GO:0051224 46 0.041
organonitrogen compound catabolic process GO:1901565 264 0.041
Human
negative regulation of cytokine production GO:0001818 84 0.040
golgi to endosome transport GO:0006895 3 0.040
lipid biosynthetic process GO:0008610 179 0.040
cellular macromolecule catabolic process GO:0044265 206 0.040
purine nucleoside metabolic process GO:0042278 241 0.040
Human
ras protein signal transduction GO:0007265 77 0.040
tube closure GO:0060606 91 0.039
Mouse
cytoplasmic transport GO:0016482 234 0.039
regulation of cell migration GO:0030334 219 0.039
mesodermal cell migration GO:0008078 4 0.039
muscle cell differentiation GO:0042692 261 0.038
action potential GO:0001508 78 0.038
purine ribonucleotide catabolic process GO:0009154 208 0.038
Human
digestive tract morphogenesis GO:0048546 147 0.038
regulation of neurotransmitter levels GO:0001505 87 0.038
kidney development GO:0001822 213 0.038
misfolded protein transport GO:0070843 1 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
Human
response to temperature stimulus GO:0009266 55 0.037
regulation of microtubule cytoskeleton organization GO:0070507 37 0.037
microtubule cytoskeleton organization GO:0000226 157 0.037
regulation of b cell differentiation GO:0045577 23 0.037
b cell activation GO:0042113 161 0.037
wnt signaling pathway GO:0016055 188 0.037
regulation of wnt signaling pathway GO:0030111 123 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.036
Human
protein ubiquitination GO:0016567 171 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
Human
cerebellar granular layer development GO:0021681 13 0.036
epithelial tube formation GO:0072175 130 0.036
Mouse
engulfment of apoptotic cell GO:0043652 3 0.035
positive regulation of apoptotic signaling pathway GO:2001235 95 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
regulation of t cell proliferation GO:0042129 92 0.034
organophosphate catabolic process GO:0046434 232 0.034
Human
cilium assembly GO:0042384 81 0.034
guanosine containing compound catabolic process GO:1901069 144 0.034
receptor mediated endocytosis GO:0006898 51 0.034
regulation of cytokine production GO:0001817 266 0.033
protein import GO:0017038 101 0.033
negative regulation of nervous system development GO:0051961 156 0.033
microtubule based movement GO:0007018 84 0.033
actin filament organization GO:0007015 113 0.033
striated muscle tissue development GO:0014706 293 0.032
t cell activation GO:0042110 289 0.032
regulation of intracellular transport GO:0032386 159 0.032
transition metal ion homeostasis GO:0055076 54 0.032
cytokine production GO:0001816 319 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
apoptotic signaling pathway GO:0097190 306 0.031
ameboidal type cell migration GO:0001667 128 0.031
negative regulation of interleukin 17 production GO:0032700 5 0.031
regulation of t cell activation GO:0050863 170 0.030
positive regulation of cell death GO:0010942 224 0.030
cytokinetic process GO:0032506 2 0.030
nucleoside triphosphate catabolic process GO:0009143 205 0.029
Human
regulation of voltage gated calcium channel activity GO:1901385 4 0.029
positive regulation of programmed cell death GO:0043068 218 0.029
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.029
regulation of necrotic cell death GO:0010939 13 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
cellular response to growth factor stimulus GO:0071363 197 0.028
synaptic vesicle recycling GO:0036465 19 0.028
positive regulation of cell migration GO:0030335 109 0.028
negative regulation of immune system process GO:0002683 209 0.028
neuronal action potential GO:0019228 54 0.028
transmission of nerve impulse GO:0019226 76 0.028
cation homeostasis GO:0055080 212 0.028
cilium movement GO:0003341 28 0.028
mitotic cell cycle GO:0000278 195 0.028
axonogenesis GO:0007409 274 0.028
modification dependent protein catabolic process GO:0019941 133 0.028
mitotic cell cycle process GO:1903047 159 0.028
cognition GO:0050890 149 0.027
establishment of melanosome localization GO:0032401 11 0.027
interleukin 17 production GO:0032620 11 0.027
establishment of organelle localization GO:0051656 122 0.027
i kappab kinase nf kappab signaling GO:0007249 85 0.027
establishment or maintenance of cell polarity GO:0007163 86 0.027
regulation of smoothened signaling pathway GO:0008589 58 0.027
phagosome maturation GO:0090382 4 0.027
leukocyte proliferation GO:0070661 172 0.027
positive regulation of neuron projection development GO:0010976 79 0.027
endoderm development GO:0007492 45 0.027
regulation of intracellular protein transport GO:0033157 82 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
Human
digestive tract development GO:0048565 190 0.026
cellular protein complex disassembly GO:0043624 36 0.026
synaptic vesicle transport GO:0048489 57 0.026
regulation of b cell activation GO:0050864 81 0.026
cellular lipid metabolic process GO:0044255 323 0.026
axon ensheathment GO:0008366 76 0.026
skeletal muscle organ development GO:0060538 163 0.026
rho protein signal transduction GO:0007266 32 0.026
germ cell development GO:0007281 185 0.026
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.026
regulation of leukocyte differentiation GO:1902105 159 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.025
intraciliary transport GO:0042073 9 0.025
sensory perception of mechanical stimulus GO:0050954 107 0.025
heterocycle catabolic process GO:0046700 280 0.025
Human
protein depolymerization GO:0051261 34 0.025
sarcomere organization GO:0045214 24 0.025
negative regulation of molecular function GO:0044092 258 0.025
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
cell type specific apoptotic process GO:0097285 268 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
Human
protein refolding GO:0042026 1 0.024
negative regulation of cytoskeleton organization GO:0051494 36 0.024
necrotic cell death GO:0070265 30 0.024
regulation of secretion GO:0051046 274 0.024
regulation of myeloid cell differentiation GO:0045637 96 0.024
positive regulation of erythrocyte differentiation GO:0045648 11 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
lymphocyte differentiation GO:0030098 242 0.024
positive regulation of intracellular transport GO:0032388 70 0.023
protein import into nucleus GO:0006606 95 0.023
regulation of cellular component size GO:0032535 121 0.023
positive regulation of notch signaling pathway GO:0045747 18 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
Mouse
negative regulation of cell proliferation GO:0008285 296 0.023
nucleotide metabolic process GO:0009117 332 0.023
Human
fat cell differentiation GO:0045444 160 0.023
muscle system process GO:0003012 141 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
Human
regulation of alpha beta t cell activation GO:0046634 53 0.022
response to growth factor GO:0070848 198 0.022
photoreceptor cell differentiation GO:0046530 52 0.022
neuron death GO:0070997 154 0.022
dna repair GO:0006281 107 0.022
sensory perception GO:0007600 245 0.022
lymphocyte proliferation GO:0046651 164 0.022
neutrophil chemotaxis GO:0030593 36 0.022
ribonucleoside monophosphate catabolic process GO:0009158 57 0.022
Human
non canonical wnt signaling pathway GO:0035567 33 0.022
endocytosis GO:0006897 168 0.022
golgi vesicle transport GO:0048193 30 0.022
positive regulation of cell motility GO:2000147 116 0.022
lymphocyte homeostasis GO:0002260 64 0.021
regulation of protein import into nucleus GO:0042306 52 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
melanosome localization GO:0032400 12 0.021
membrane invagination GO:0010324 17 0.021
cytokinesis GO:0000910 17 0.021
positive regulation of phagocytosis engulfment GO:0060100 3 0.021
sensory organ morphogenesis GO:0090596 242 0.021
positive regulation of t cell activation GO:0050870 101 0.021
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.021
cellular ketone metabolic process GO:0042180 84 0.021
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.021
tube formation GO:0035148 140 0.021
Mouse
muscle fiber development GO:0048747 76 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
Human
macromolecule catabolic process GO:0009057 281 0.021
neuron neuron synaptic transmission GO:0007270 69 0.021
regulation of interleukin 17 production GO:0032660 8 0.020
negative regulation of growth GO:0045926 99 0.020
synapse assembly GO:0007416 56 0.020
dendrite development GO:0016358 115 0.020
calcineurin nfat signaling cascade GO:0033173 8 0.020
organelle localization GO:0051640 179 0.020
regulation of lymphocyte differentiation GO:0045619 107 0.020
cell adhesion GO:0007155 329 0.020
urogenital system development GO:0001655 261 0.020
exocytosis GO:0006887 121 0.020
positive regulation of lymphocyte proliferation GO:0050671 70 0.020
protein complex disassembly GO:0043241 40 0.020
regulation of endocytosis GO:0030100 69 0.020
response to oxidative stress GO:0006979 123 0.020
regulation of protein complex assembly GO:0043254 83 0.020
microtubule based process GO:0007017 236 0.020
morphogenesis of a polarized epithelium GO:0001738 37 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.019
synaptic growth at neuromuscular junction GO:0051124 6 0.019
macromolecular complex disassembly GO:0032984 43 0.019
lymphocyte mediated immunity GO:0002449 139 0.019
dna metabolic process GO:0006259 303 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
learning or memory GO:0007611 148 0.019
regulation of synapse assembly GO:0051963 29 0.019
amide transport GO:0042886 138 0.019
angiogenesis GO:0001525 201 0.019
regulation of hormone levels GO:0010817 211 0.019
regulation of microtubule based process GO:0032886 52 0.019
regulation of cell projection assembly GO:0060491 38 0.019
positive regulation of cell cycle GO:0045787 92 0.018
regulation of erythrocyte differentiation GO:0045646 23 0.018
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 14 0.018
lipoprotein metabolic process GO:0042157 43 0.018
lipoprotein biosynthetic process GO:0042158 33 0.018
regulation of cell adhesion mediated by integrin GO:0033628 13 0.018
neutrophil migration GO:1990266 37 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.018
regulation of neuron projection development GO:0010975 169 0.018
muscle cell development GO:0055001 133 0.017
negative regulation of organelle organization GO:0010639 90 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
Human
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.017
sensory perception of sound GO:0007605 97 0.017
gpi anchor metabolic process GO:0006505 7 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
nuclear import GO:0051170 95 0.017
inclusion body assembly GO:0070841 3 0.017
actomyosin structure organization GO:0031032 56 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
positive regulation of t cell differentiation GO:0045582 52 0.017
mitochondrial transport GO:0006839 36 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
oocyte construction GO:0007308 2 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
regulation of cell cycle g2 m phase transition GO:1902749 10 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
gonad development GO:0008406 141 0.017
peptide secretion GO:0002790 114 0.016
amine metabolic process GO:0009308 45 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
genitalia development GO:0048806 37 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
membrane tubulation GO:0097320 4 0.016
regulation of transferase activity GO:0051338 263 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
camera type eye development GO:0043010 266 0.016
regulation of homeostatic process GO:0032844 182 0.016
determination of left right symmetry GO:0007368 80 0.016
nitrogen compound transport GO:0071705 271 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
regulation of neural precursor cell proliferation GO:2000177 70 0.016
single organism nuclear import GO:1902593 95 0.016
inositol phosphate mediated signaling GO:0048016 13 0.016
associative learning GO:0008306 61 0.016
lamellipodium morphogenesis GO:0072673 5 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
Human
apoptotic mitochondrial changes GO:0008637 48 0.016
endodermal cell fate specification GO:0001714 4 0.015
regulation of lymphocyte mediated immunity GO:0002706 84 0.015
glycerolipid biosynthetic process GO:0045017 50 0.015
vesicle organization GO:0016050 60 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
leukocyte homeostasis GO:0001776 79 0.015
cellular amino acid metabolic process GO:0006520 103 0.015
positive regulation of leukocyte proliferation GO:0070665 73 0.015
establishment of synaptic vesicle localization GO:0097480 57 0.015
positive regulation of cell activation GO:0050867 158 0.015
positive regulation of myeloid cell differentiation GO:0045639 43 0.015
ensheathment of neurons GO:0007272 76 0.015
neural precursor cell proliferation GO:0061351 121 0.015
cellular homeostasis GO:0019725 240 0.015
regulation of transmembrane transport GO:0034762 128 0.015
blood vessel morphogenesis GO:0048514 285 0.015
cellular component maintenance GO:0043954 11 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
positive regulation of intracellular protein transport GO:0090316 42 0.015
epithelial cell proliferation GO:0050673 174 0.015
synaptic vesicle endocytosis GO:0048488 19 0.015
mitochondrion degradation GO:0000422 3 0.014
positive regulation of nfat protein import into nucleus GO:0051533 1 0.014
response to peptide hormone GO:0043434 127 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
glycosylation GO:0070085 62 0.014
response to organonitrogen compound GO:0010243 246 0.014
muscle tissue development GO:0060537 308 0.014
regulation of cell cycle GO:0051726 281 0.014
hematopoietic stem cell migration GO:0035701 1 0.014
regulation of notch signaling pathway GO:0008593 35 0.014
actin filament bundle assembly GO:0051017 40 0.014
regulation of transporter activity GO:0032409 57 0.014
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
Human
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.014
neurotransmitter secretion GO:0007269 62 0.014
positive regulation of protein modification process GO:0031401 299 0.014
positive regulation of cell adhesion GO:0045785 80 0.014
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
positive regulation of cell development GO:0010720 237 0.014
regulation of system process GO:0044057 200 0.014
regulation of protein complex disassembly GO:0043244 28 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
Human
cellular chemical homeostasis GO:0055082 215 0.014
digestive system development GO:0055123 200 0.013
regulation of t cell differentiation GO:0045580 83 0.013
multi multicellular organism process GO:0044706 109 0.013
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:1900740 3 0.013
neuron apoptotic process GO:0051402 142 0.013
protein glycosylation GO:0006486 55 0.013
positive regulation of lymphocyte differentiation GO:0045621 61 0.013
regulation of mitochondrial membrane permeability GO:0046902 17 0.013
gonad morphogenesis GO:0035262 1 0.013
positive regulation of t cell proliferation GO:0042102 52 0.013
skin development GO:0043588 220 0.013
gamma delta t cell activation GO:0046629 13 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
double strand break repair via homologous recombination GO:0000724 21 0.013
negative regulation of cell development GO:0010721 169 0.013
rna interference GO:0016246 2 0.013
response to heat GO:0009408 27 0.013
response to extracellular stimulus GO:0009991 127 0.013
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.013
regulation of actin filament bundle assembly GO:0032231 18 0.013
de novo protein folding GO:0006458 9 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
positive regulation of lamellipodium assembly GO:0010592 2 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
Human
microtubule based transport GO:0010970 50 0.013
protein localization to membrane GO:0072657 108 0.013
positive regulation of alpha beta t cell activation GO:0046635 39 0.013
regulation of vascular wound healing GO:0061043 2 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of protein kinase activity GO:0045859 232 0.013
regulation of neuron differentiation GO:0045664 281 0.013
embryonic heart tube development GO:0035050 65 0.013
negative regulation of microtubule depolymerization GO:0007026 13 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.012
cellular amine metabolic process GO:0044106 44 0.012
developmental maturation GO:0021700 193 0.012
nuclear transport GO:0051169 139 0.012
actin mediated cell contraction GO:0070252 15 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
Human
multicellular organismal signaling GO:0035637 91 0.012
hormone secretion GO:0046879 128 0.012
negative regulation of immune effector process GO:0002698 55 0.012
meiotic nuclear division GO:0007126 115 0.012
inter male aggressive behavior GO:0002121 3 0.012
vacuole organization GO:0007033 38 0.012
regulation of transcription factor import into nucleus GO:0042990 24 0.012
protein localization to vacuole GO:0072665 4 0.012
homeostasis of number of cells GO:0048872 210 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
positive regulation of protein ubiquitination GO:0031398 27 0.012
positive regulation of b cell differentiation GO:0045579 13 0.012
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
rna splicing via transesterification reactions GO:0000375 43 0.012
oligodendrocyte differentiation GO:0048709 53 0.012
leukocyte differentiation GO:0002521 342 0.012
post golgi vesicle mediated transport GO:0006892 13 0.012
regulation of microtubule depolymerization GO:0031114 13 0.012
establishment or maintenance of actin cytoskeleton polarity GO:0030950 1 0.012

Pfn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.078
disease of anatomical entity DOID:7 0 0.078
eye and adnexa disease DOID:1492 0 0.078
nervous system disease DOID:863 0 0.078
eye disease DOID:5614 0 0.078
central nervous system disease DOID:331 0 0.048
retinal disease DOID:5679 0 0.047
retinal degeneration DOID:8466 0 0.047
musculoskeletal system disease DOID:17 0 0.029
myopathy DOID:423 0 0.028
muscular disease DOID:0080000 0 0.028
muscle tissue disease DOID:66 0 0.028
muscular dystrophy DOID:9884 0 0.014
limb girdle muscular dystrophy DOID:11724 0 0.014