Mus musculus

0 known processes

Pgls

6-phosphogluconolactonase

(Aliases: 1110030K05Rik,AI447866,Plgs)

Pgls biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hexose catabolic process GO:0019320 3 0.779
sulfur compound metabolic process GO:0006790 100 0.774
cellular amino acid metabolic process GO:0006520 103 0.768
cellular modified amino acid metabolic process GO:0006575 63 0.635
pigment biosynthetic process GO:0046148 26 0.541
organonitrogen compound biosynthetic process GO:1901566 192 0.529
glutathione metabolic process GO:0006749 16 0.513
oxidation reduction process GO:0055114 342 0.503
hexose metabolic process GO:0019318 98 0.383
carbohydrate metabolic process GO:0005975 230 0.367
nucleobase containing small molecule metabolic process GO:0055086 352 0.316
alpha amino acid biosynthetic process GO:1901607 15 0.278
regulation of cellular response to stress GO:0080135 159 0.241
toxin catabolic process GO:0009407 1 0.230
monocarboxylic acid metabolic process GO:0032787 191 0.229
organophosphate biosynthetic process GO:0090407 122 0.221
nucleotide metabolic process GO:0009117 332 0.192
alpha amino acid metabolic process GO:1901605 59 0.183
protein tetramerization GO:0051262 23 0.176
monosaccharide metabolic process GO:0005996 106 0.163
leukocyte proliferation GO:0070661 172 0.162
negative regulation of nitric oxide synthase biosynthetic process GO:0051771 1 0.154
protein oligomerization GO:0051259 67 0.153
maintenance of location GO:0051235 89 0.151
posttranscriptional regulation of gene expression GO:0010608 155 0.143
monocyte chemotactic protein 1 production GO:0071605 1 0.138
lipid storage GO:0019915 36 0.136
protein localization to nucleus GO:0034504 121 0.135
protein catabolic process GO:0030163 221 0.133
organic cyclic compound catabolic process GO:1901361 295 0.132
nucleoside phosphate biosynthetic process GO:1901293 79 0.126
carboxylic acid catabolic process GO:0046395 51 0.124
small molecule catabolic process GO:0044282 71 0.122
cellular ketone metabolic process GO:0042180 84 0.122
response to oxidative stress GO:0006979 123 0.112
regulation of cellular ketone metabolic process GO:0010565 66 0.111
nucleotide biosynthetic process GO:0009165 78 0.111
organic acid catabolic process GO:0016054 51 0.110
galactose metabolic process GO:0006012 4 0.108
epidermis development GO:0008544 187 0.108
cellular amino acid biosynthetic process GO:0008652 22 0.106
translation GO:0006412 93 0.105
positive regulation of cellular amine metabolic process GO:0033240 5 0.099
ribonucleoside biosynthetic process GO:0042455 21 0.098
regulation of peroxidase activity GO:2000468 1 0.096
carbohydrate derivative biosynthetic process GO:1901137 183 0.093
amine metabolic process GO:0009308 45 0.090
cellular aldehyde metabolic process GO:0006081 12 0.087
secondary metabolite catabolic process GO:0090487 1 0.084
nucleoside phosphate metabolic process GO:0006753 338 0.075
locomotory behavior GO:0007626 195 0.075
protein homooligomerization GO:0051260 43 0.075
cellular response to lipid GO:0071396 145 0.074
peptide metabolic process GO:0006518 46 0.070
cellular amine metabolic process GO:0044106 44 0.070
lipid localization GO:0010876 126 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.068
glycosyl compound metabolic process GO:1901657 246 0.066
positive regulation of protein modification process GO:0031401 299 0.066
positive regulation of cell motility GO:2000147 116 0.066
alcohol metabolic process GO:0006066 116 0.066
response to reactive oxygen species GO:0000302 56 0.065
mesenchyme development GO:0060485 152 0.061
organonitrogen compound catabolic process GO:1901565 264 0.058
purine containing compound metabolic process GO:0072521 311 0.057
organic heteropentacyclic compound catabolic process GO:1901377 1 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
regulation of cellular amine metabolic process GO:0033238 20 0.056
multicellular organismal aging GO:0010259 24 0.056
purine containing compound biosynthetic process GO:0072522 70 0.055
cell fate determination involved in pattern specification GO:0060582 1 0.055
purine nucleoside metabolic process GO:0042278 241 0.053
acetylcholine transport GO:0015870 2 0.053
carbohydrate catabolic process GO:0016052 32 0.052
protein homotetramerization GO:0051289 12 0.052
cellular response to extracellular stimulus GO:0031668 81 0.052
ribonucleoside metabolic process GO:0009119 245 0.051
purine nucleobase metabolic process GO:0006144 4 0.051
regulation of kinase activity GO:0043549 249 0.050
response to amino acid GO:0043200 37 0.050
carbohydrate derivative catabolic process GO:1901136 231 0.049
myosin filament organization GO:0031033 3 0.048
aromatic compound catabolic process GO:0019439 286 0.048
lymphocyte proliferation GO:0046651 164 0.048
myofibril assembly GO:0030239 34 0.048
actin cytoskeleton organization GO:0030036 220 0.045
pigment metabolic process GO:0042440 32 0.045
actomyosin structure organization GO:0031032 56 0.044
macromolecule catabolic process GO:0009057 281 0.044
mesonephric tubule development GO:0072164 94 0.043
organic hydroxy compound metabolic process GO:1901615 203 0.040
cellular component assembly involved in morphogenesis GO:0010927 139 0.040
regulation of translation GO:0006417 71 0.039
ureteric bud development GO:0001657 94 0.039
determination of adult lifespan GO:0008340 11 0.038
nucleoside metabolic process GO:0009116 246 0.037
carboxylic acid biosynthetic process GO:0046394 86 0.036
compound eye development GO:0048749 1 0.036
response to acid chemical GO:0001101 111 0.036
nucleotide sugar metabolic process GO:0009225 4 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
cellular homeostasis GO:0019725 240 0.035
ubiquitin dependent protein catabolic process GO:0006511 129 0.034
mesenchymal cell development GO:0014031 93 0.034
negative regulation of molecular function GO:0044092 258 0.034
apoptotic signaling pathway GO:0097190 306 0.033
t cell proliferation GO:0042098 120 0.033
nadph regeneration GO:0006740 2 0.033
cellular modified amino acid biosynthetic process GO:0042398 12 0.032
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
modification dependent macromolecule catabolic process GO:0043632 133 0.031
purine nucleoside biosynthetic process GO:0042451 19 0.030
cellular response to dna damage stimulus GO:0006974 207 0.030
glucose metabolic process GO:0006006 92 0.029
response to temperature stimulus GO:0009266 55 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.028
regulation of transferase activity GO:0051338 263 0.028
organic acid biosynthetic process GO:0016053 86 0.028
positive regulation of cell migration GO:0030335 109 0.028
aflatoxin metabolic process GO:0046222 1 0.027
response to steroid hormone GO:0048545 56 0.027
response to inorganic substance GO:0010035 96 0.027
keratinocyte differentiation GO:0030216 48 0.027
cellular response to lipopolysaccharide GO:0071222 77 0.027
embryonic placenta development GO:0001892 98 0.027
response to nutrient levels GO:0031667 109 0.026
male gamete generation GO:0048232 285 0.026
metal ion homeostasis GO:0055065 189 0.026
rhythmic process GO:0048511 174 0.026
muscle cell development GO:0055001 133 0.026
negative regulation of monocyte chemotactic protein 1 production GO:0071638 1 0.026
organelle assembly GO:0070925 177 0.026
protein modification by small protein conjugation GO:0032446 187 0.025
mesenchymal cell differentiation GO:0048762 107 0.025
nadp metabolic process GO:0006739 6 0.025
response to peptide hormone GO:0043434 127 0.025
regulation of monocyte chemotactic protein 1 production GO:0071637 1 0.025
response to oxygen levels GO:0070482 62 0.025
regulation of bmp signaling pathway GO:0030510 60 0.024
skin development GO:0043588 220 0.024
placenta development GO:0001890 140 0.024
peptidyl amino acid modification GO:0018193 336 0.024
positive regulation of mapk cascade GO:0043410 170 0.023
regulation of protein kinase activity GO:0045859 232 0.023
purine nucleobase biosynthetic process GO:0009113 3 0.023
coenzyme metabolic process GO:0006732 52 0.023
tissue migration GO:0090130 68 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
cytoplasmic transport GO:0016482 234 0.023
nucleocytoplasmic transport GO:0006913 139 0.023
epithelial cell proliferation GO:0050673 174 0.022
nucleoside biosynthetic process GO:0009163 21 0.022
limb development GO:0060173 166 0.022
gland development GO:0048732 330 0.021
response to lipopolysaccharide GO:0032496 128 0.021
regulation of cell motility GO:2000145 236 0.021
regulation of mapk cascade GO:0043408 248 0.020
regulation of cell migration GO:0030334 219 0.020
response to uv GO:0009411 44 0.020
organic heteropentacyclic compound metabolic process GO:1901376 1 0.020
superoxide metabolic process GO:0006801 27 0.020
peptidyl serine modification GO:0018209 83 0.019
inflammatory response GO:0006954 244 0.019
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
cellular response to abiotic stimulus GO:0071214 56 0.019
response to hydrogen peroxide GO:0042542 32 0.018
smoothened signaling pathway GO:0007224 105 0.018
establishment of protein localization to organelle GO:0072594 118 0.018
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.018
response to monosaccharide GO:0034284 67 0.018
regulation of map kinase activity GO:0043405 120 0.018
short chain fatty acid catabolic process GO:0019626 2 0.017
glycosyl compound biosynthetic process GO:1901659 21 0.017
multicellular organism growth GO:0035264 161 0.017
cofactor metabolic process GO:0051186 80 0.017
cell substrate adhesion GO:0031589 130 0.017
gene silencing by rna GO:0031047 19 0.017
placenta blood vessel development GO:0060674 31 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
regulation of organ morphogenesis GO:2000027 144 0.016
positive regulation of kinase activity GO:0033674 155 0.016
striated muscle tissue development GO:0014706 293 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
mesonephric epithelium development GO:0072163 94 0.016
single organism nuclear import GO:1902593 95 0.016
cellular amide metabolic process GO:0043603 58 0.016
spermatogenesis GO:0007283 284 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
pentose metabolic process GO:0019321 5 0.015
gonad development GO:0008406 141 0.015
homeostasis of number of cells GO:0048872 210 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
negative regulation of chemokine production GO:0032682 4 0.015
regulation of reproductive process GO:2000241 66 0.015
protein localization to organelle GO:0033365 185 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
cardiac ventricle development GO:0003231 83 0.015
mesonephros development GO:0001823 97 0.015
striated muscle cell development GO:0055002 125 0.015
translational initiation GO:0006413 24 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
myosin filament assembly GO:0031034 2 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
cellular amino acid catabolic process GO:0009063 25 0.014
c4 dicarboxylate transport GO:0015740 3 0.014
small molecule biosynthetic process GO:0044283 132 0.014
muscle cell differentiation GO:0042692 261 0.014
blood vessel morphogenesis GO:0048514 285 0.014
cellular response to oxidative stress GO:0034599 76 0.014
response to muscle stretch GO:0035994 1 0.014
kidney development GO:0001822 213 0.014
wnt signaling pathway GO:0016055 188 0.014
alpha amino acid catabolic process GO:1901606 18 0.014
heme biosynthetic process GO:0006783 12 0.014
protein import GO:0017038 101 0.014
aflatoxin catabolic process GO:0046223 1 0.014
glial cell differentiation GO:0010001 131 0.014
stem cell differentiation GO:0048863 268 0.014
alditol metabolic process GO:0019400 5 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
covalent chromatin modification GO:0016569 163 0.014
regulation of ion transport GO:0043269 215 0.013
response to stilbenoid GO:0035634 22 0.013
cellular response to nutrient levels GO:0031669 64 0.013
regulation of chemokine production GO:0032642 30 0.013
cellular ion homeostasis GO:0006873 165 0.013
response to xenobiotic stimulus GO:0009410 13 0.013
mapk cascade GO:0000165 281 0.013
cellular transition metal ion homeostasis GO:0046916 32 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
epithelial cell migration GO:0010631 63 0.013
aldehyde catabolic process GO:0046185 4 0.013
bmp signaling pathway GO:0030509 93 0.013
coenzyme a metabolic process GO:0015936 8 0.013
regulation of superoxide anion generation GO:0032928 4 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
steroid metabolic process GO:0008202 119 0.012
response to interleukin 4 GO:0070670 23 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
cellular response to external stimulus GO:0071496 88 0.012
cellular chemical homeostasis GO:0055082 215 0.012
regulation of intracellular transport GO:0032386 159 0.012
development of primary sexual characteristics GO:0045137 143 0.012
nucleoside bisphosphate metabolic process GO:0033865 9 0.012
multi multicellular organism process GO:0044706 109 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
translational elongation GO:0006414 12 0.012
protein stabilization GO:0050821 25 0.012
kidney epithelium development GO:0072073 121 0.012
response to light stimulus GO:0009416 135 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
cardiocyte differentiation GO:0035051 87 0.012
myeloid cell homeostasis GO:0002262 114 0.012
fibroblast proliferation GO:0048144 35 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
germ cell development GO:0007281 185 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
detection of muscle stretch GO:0035995 1 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
insulin secretion GO:0030073 89 0.012
urogenital system development GO:0001655 261 0.012
genitalia development GO:0048806 37 0.011
cytokine production GO:0001816 319 0.011
response to heat GO:0009408 27 0.011
cardiac muscle cell differentiation GO:0055007 69 0.011
liver development GO:0001889 66 0.011
rna interference GO:0016246 2 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
t cell activation GO:0042110 289 0.011
activation of mapk activity GO:0000187 59 0.011
regulation of secretion by cell GO:1903530 249 0.011
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.011
negative regulation of glial cell proliferation GO:0060253 4 0.011
inhibition of neuroepithelial cell differentiation GO:0002085 2 0.011
response to organic cyclic compound GO:0014070 198 0.011
response to oxygen radical GO:0000305 16 0.011
chemokine production GO:0032602 34 0.011
bile acid secretion GO:0032782 2 0.011
stem cell development GO:0048864 219 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
nucleobase biosynthetic process GO:0046112 3 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
respiratory tube development GO:0030323 167 0.010
positive regulation of bmp signaling pathway GO:0030513 23 0.010
response to phenylpropanoid GO:0080184 22 0.010
response to hypoxia GO:0001666 58 0.010
cellular response to steroid hormone stimulus GO:0071383 33 0.010
lymphocyte homeostasis GO:0002260 64 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
copper ion transport GO:0006825 10 0.010
response to glucocorticoid GO:0051384 20 0.010
establishment of tissue polarity GO:0007164 28 0.010
inner ear receptor cell differentiation GO:0060113 61 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
camera type eye development GO:0043010 266 0.010

Pgls disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.141
carbohydrate metabolic disorder DOID:2978 0 0.141
inherited metabolic disorder DOID:655 0 0.141
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012