|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.994
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.985
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.970
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.965
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.946
|
|
|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
3 |
0.934
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.922
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.922
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.908
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.899
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.893
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.892
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.885
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.867
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.864
|
Rat |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.861
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.852
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.850
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.849
|
Mouse |
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.826
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.819
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.811
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.803
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.801
|
|
|
|
learning
|
GO:0007612 |
98 |
0.799
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.798
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.782
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.781
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.780
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.779
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.773
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.766
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.766
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.765
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.757
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.756
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.739
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.737
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.732
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.730
|
|
|
|
maternal process involved in female pregnancy
|
GO:0060135 |
32 |
0.727
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.716
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.711
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.708
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.708
|
|
|
|
steroid hormone mediated signaling pathway
|
GO:0043401 |
6 |
0.701
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.691
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.671
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.670
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.668
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.665
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.663
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.663
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.662
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.662
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.658
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.658
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.655
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.653
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.647
|
|
|
|
vasoconstriction
|
GO:0042310 |
27 |
0.644
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.632
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.629
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.628
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.616
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.615
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.601
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.599
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.597
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.596
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.593
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.592
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.591
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.586
|
|
|
|
response to histamine
|
GO:0034776 |
1 |
0.584
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.580
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.572
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.568
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.566
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.560
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.557
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.554
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.554
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.543
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.542
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.535
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.522
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.522
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.521
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.517
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.517
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.515
|
|
|
|
trophectodermal cellular morphogenesis
|
GO:0001831 |
3 |
0.514
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.513
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.511
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.499
|
|
|
|
response to pain
|
GO:0048265 |
26 |
0.498
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.494
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.492
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.486
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.483
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.483
|
|
|
|
fear response
|
GO:0042596 |
33 |
0.480
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.477
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.476
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.473
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.472
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.471
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.468
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.467
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.466
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.466
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.465
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.463
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
25 |
0.462
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.461
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.455
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.453
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.453
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.452
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.452
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.451
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.447
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.447
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.442
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.441
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.441
|
|
|
|
lateral mesodermal cell fate commitment
|
GO:0048372 |
2 |
0.436
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.432
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.432
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.432
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.432
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.425
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.420
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.420
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.420
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.419
|
Mouse |
|
|
somatostatin signaling pathway
|
GO:0038170 |
2 |
0.418
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.412
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.408
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.408
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.406
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.405
|
Mouse |
|
|
antral ovarian follicle growth
|
GO:0001547 |
5 |
0.405
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.405
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.403
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.403
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.398
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.398
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.395
|
Mouse |
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.393
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.387
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.385
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.381
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.378
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.378
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.372
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.370
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.367
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.362
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.362
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.359
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.357
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.356
|
|
|
|
memory
|
GO:0007613 |
58 |
0.355
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.354
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.352
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.350
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.349
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.349
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.348
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.348
|
|
|
|
somatostatin receptor signaling pathway
|
GO:0038169 |
2 |
0.346
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.343
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.341
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.340
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.336
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.335
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.333
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.332
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.332
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.330
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.329
|
|
|
|
positive regulation of inositol phosphate biosynthetic process
|
GO:0060732 |
2 |
0.327
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.325
|
Mouse |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.325
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.323
|
Rat |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.323
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.320
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.318
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.316
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.315
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.312
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.312
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.311
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
19 |
0.311
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.308
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.307
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.306
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.306
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.300
|
|
|
|
prostate gland development
|
GO:0030850 |
48 |
0.298
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.298
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.297
|
|
|
|
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
|
GO:0014834 |
3 |
0.293
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.292
|
Mouse |
|
|
cell growth
|
GO:0016049 |
130 |
0.291
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.290
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.288
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.284
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.284
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.284
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.279
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.279
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.278
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.277
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.274
|
|
|
|
mucosal associated lymphoid tissue development
|
GO:0048537 |
12 |
0.273
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.272
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.271
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.270
|
Mouse |
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.270
|
|
|
|
cell proliferation in hindbrain
|
GO:0021534 |
10 |
0.269
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.266
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.265
|
|
|
|
prostate gland growth
|
GO:0060736 |
13 |
0.263
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.263
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.262
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.262
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.262
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.261
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.261
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.260
|
Rat |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.258
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.256
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.255
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.247
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.247
|
Rat |
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.245
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.244
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
3 |
0.244
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.240
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.239
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.238
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.238
|
|
|
|
regulation of the force of heart contraction
|
GO:0002026 |
17 |
0.238
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.235
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.235
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.235
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.233
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.230
|
Mouse |
|
|
trophectodermal cell proliferation
|
GO:0001834 |
2 |
0.229
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.229
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.224
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
3 |
0.224
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.223
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.223
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.220
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.219
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.218
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.217
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.217
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.217
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.217
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.215
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.215
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.212
|
|
|
|
regulation of vasoconstriction
|
GO:0019229 |
14 |
0.211
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.210
|
Mouse |
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.209
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.209
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.209
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.209
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.208
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.208
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.206
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.206
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.206
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.205
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.203
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.202
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.201
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.201
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.199
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.198
|
|
|
|
reflex
|
GO:0060004 |
22 |
0.198
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.198
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.197
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.197
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.196
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.193
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.192
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.192
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
21 |
0.191
|
|
|
|
negative regulation of synaptic transmission glutamatergic
|
GO:0051967 |
4 |
0.190
|
|
|
|
proteoglycan biosynthetic process
|
GO:0030166 |
20 |
0.186
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.186
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.186
|
Mouse |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.186
|
|
|
|
water homeostasis
|
GO:0030104 |
27 |
0.185
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.183
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.182
|
Rat |
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.182
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.181
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.181
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.181
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.180
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.180
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.180
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.179
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.179
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.178
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.178
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.178
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.177
|
|
|
|
catecholamine secretion
|
GO:0050432 |
15 |
0.177
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.176
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.175
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.174
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.174
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.171
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.171
|
|
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.170
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.170
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.170
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.170
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.169
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.169
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.169
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
2 |
0.168
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
22 |
0.168
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.168
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.167
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.167
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.166
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.166
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.166
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.165
|
|
|
|
maintenance of cell number
|
GO:0098727 |
3 |
0.165
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.165
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.164
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.164
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.164
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.164
|
|
|
|
lateral mesodermal cell differentiation
|
GO:0048371 |
3 |
0.163
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.163
|
|
|
|
neural plate mediolateral regionalization
|
GO:0021998 |
1 |
0.161
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.161
|
Rat |
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.161
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.161
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.161
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.159
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.158
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.157
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.157
|
|
|
|
positive regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033145 |
4 |
0.157
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.155
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.155
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.153
|
|
|
|
response to morphine
|
GO:0043278 |
9 |
0.153
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.152
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.152
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.152
|
|
|
|
response to isoquinoline alkaloid
|
GO:0014072 |
9 |
0.152
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.152
|
|
|
|
gamma aminobutyric acid signaling pathway
|
GO:0007214 |
8 |
0.151
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.151
|
|
|
|
regulation of morphogenesis of a branching structure
|
GO:0060688 |
53 |
0.151
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.151
|
|
|
|
peristalsis
|
GO:0030432 |
8 |
0.150
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.148
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.148
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.147
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.147
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.146
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.146
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.146
|
|
|
|
optic nerve structural organization
|
GO:0021633 |
2 |
0.145
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.145
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.143
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.143
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.143
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.143
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.142
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.141
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.141
|
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.141
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.141
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.141
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.140
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
7 |
0.139
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.139
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.139
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.138
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.138
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.138
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.137
|
|
|
|
response to estrogen
|
GO:0043627 |
24 |
0.137
|
Rat |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.137
|
|
|
|
lateral mesoderm formation
|
GO:0048370 |
3 |
0.136
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
32 |
0.136
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.135
|
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
3 |
0.134
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.133
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.133
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.131
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
41 |
0.131
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.130
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.130
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.130
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.130
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.129
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.129
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.129
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.126
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.126
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.125
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.125
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.123
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.123
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.122
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.122
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.122
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.122
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.121
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.121
|
|
|
|
prostate epithelial cord elongation
|
GO:0060523 |
3 |
0.121
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.121
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
15 |
0.121
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.120
|
|
|
|
regulation of saliva secretion
|
GO:0046877 |
2 |
0.120
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.119
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.118
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.118
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.118
|
|
|
|
regulation of heart rate
|
GO:0002027 |
36 |
0.117
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.117
|
|
|
|
negative regulation of reproductive process
|
GO:2000242 |
31 |
0.117
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.117
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.117
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.116
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.115
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.114
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
8 |
0.113
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.112
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.111
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.111
|
|
|
|
histamine induced gastric acid secretion
|
GO:0001697 |
1 |
0.110
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.110
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.110
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.109
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.109
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.109
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.109
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.108
|
|
|
|
operant conditioning
|
GO:0035106 |
2 |
0.108
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.106
|
|
|
|
adult walking behavior
|
GO:0007628 |
41 |
0.106
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.106
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.105
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.104
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.104
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.104
|
|
|
|
regulation of tolerance induction to self antigen
|
GO:0002649 |
1 |
0.104
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.103
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.103
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
13 |
0.103
|
|
|
|
metanephric tubule development
|
GO:0072170 |
18 |
0.103
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.103
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.102
|
|
|
|
mammary gland alveolus development
|
GO:0060749 |
22 |
0.101
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.101
|
Mouse |
|
|
mammary gland epithelial cell differentiation
|
GO:0060644 |
13 |
0.101
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.100
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.100
|
Mouse |
|
|
osteoblast development
|
GO:0002076 |
17 |
0.099
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.099
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.099
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.099
|
|
|
|
receptor internalization
|
GO:0031623 |
16 |
0.098
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.098
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.098
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.097
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.096
|
|
|
|
inner ear receptor cell development
|
GO:0060119 |
39 |
0.096
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.095
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.095
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.095
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.094
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
17 |
0.094
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.094
|
|
|
|
regulation of dopamine uptake involved in synaptic transmission
|
GO:0051584 |
2 |
0.093
|
|
|
|
anatomical structure arrangement
|
GO:0048532 |
20 |
0.093
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.093
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.093
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.093
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.092
|
|
|
|
camp mediated signaling
|
GO:0019933 |
15 |
0.092
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
35 |
0.092
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
13 |
0.092
|
|
