Mus musculus

20 known processes

Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

(Aliases: Hyp,HPDR,PEX,HPDR1,Gy)

Phex biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ossification GO:0001503 216 0.993
cellular phosphate ion homeostasis GO:0030643 2 0.992
cell maturation GO:0048469 127 0.869
cation homeostasis GO:0055080 212 0.850
stem cell development GO:0048864 219 0.829
skeletal system development GO:0001501 356 0.812
divalent inorganic anion homeostasis GO:0072505 5 0.805
glial cell differentiation GO:0010001 131 0.775
embryonic organ morphogenesis GO:0048562 276 0.767
stem cell maintenance GO:0019827 130 0.759
nitrogen compound transport GO:0071705 271 0.759
leukocyte differentiation GO:0002521 342 0.724
skeletal system morphogenesis GO:0048705 203 0.711
mineralocorticoid biosynthetic process GO:0006705 1 0.710
metal ion homeostasis GO:0055065 189 0.688
response to fibroblast growth factor GO:0071774 47 0.674
hormone secretion GO:0046879 128 0.663
regulation of secretion GO:0051046 274 0.662
positive regulation of neuron apoptotic process GO:0043525 25 0.630
cation transmembrane transport GO:0098655 266 0.599
aldosterone biosynthetic process GO:0032342 1 0.585
regulation of hormone levels GO:0010817 211 0.581
sensory organ morphogenesis GO:0090596 242 0.581
regulation of apoptotic signaling pathway GO:2001233 197 0.571
regulation of secretion by cell GO:1903530 249 0.570
second messenger mediated signaling GO:0019932 73 0.568
organic hydroxy compound metabolic process GO:1901615 203 0.563
myeloid leukocyte differentiation GO:0002573 119 0.558
negative regulation of lipid metabolic process GO:0045833 30 0.542
positive regulation of neuron death GO:1901216 28 0.540
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.537
fat cell differentiation GO:0045444 160 0.536
chondrocyte differentiation GO:0002062 72 0.533
lipid biosynthetic process GO:0008610 179 0.530
anion transport GO:0006820 177 0.526
cellular homeostasis GO:0019725 240 0.515
cellular divalent inorganic anion homeostasis GO:0072501 3 0.513
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.511
cellular ion homeostasis GO:0006873 165 0.506
positive regulation of apoptotic process GO:0043065 217 0.499
bone remodeling GO:0046849 53 0.477
aldosterone metabolic process GO:0032341 2 0.472
regulation of hormone secretion GO:0046883 88 0.471
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.463
response to acid chemical GO:0001101 111 0.453
connective tissue development GO:0061448 179 0.448
response to growth factor GO:0070848 198 0.426
positive regulation of mapk cascade GO:0043410 170 0.424
cellular response to external stimulus GO:0071496 88 0.413
peptidyl tyrosine modification GO:0018212 145 0.408
gliogenesis GO:0042063 141 0.405
cellular response to growth factor stimulus GO:0071363 197 0.397
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.391
organic hydroxy compound biosynthetic process GO:1901617 77 0.386
cellular ketone metabolic process GO:0042180 84 0.378
striated muscle tissue development GO:0014706 293 0.375
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.370
regulation of mapk cascade GO:0043408 248 0.368
cartilage development GO:0051216 140 0.366
cellular calcium ion homeostasis GO:0006874 119 0.357
forebrain development GO:0030900 302 0.353
limb morphogenesis GO:0035108 149 0.353
lymphocyte differentiation GO:0030098 242 0.346
developmental programmed cell death GO:0010623 41 0.343
positive regulation of programmed cell death GO:0043068 218 0.343
ribose phosphate metabolic process GO:0019693 291 0.341
kidney development GO:0001822 213 0.336
phosphate ion transmembrane transport GO:0035435 2 0.336
axial mesoderm formation GO:0048320 3 0.333
calcium ion homeostasis GO:0055074 127 0.330
negative regulation of steroid metabolic process GO:0045939 8 0.327
inorganic anion transmembrane transport GO:0098661 29 0.326
embryonic limb morphogenesis GO:0030326 126 0.322
apoptotic signaling pathway GO:0097190 306 0.311
muscle cell proliferation GO:0033002 52 0.310
epithelial cell development GO:0002064 159 0.306
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.294
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.290
response to organic cyclic compound GO:0014070 198 0.289
neuronal stem cell division GO:0036445 10 0.288
phosphate ion homeostasis GO:0055062 5 0.286
response to inorganic substance GO:0010035 96 0.284
appendage development GO:0048736 166 0.283
embryonic skeletal system development GO:0048706 120 0.280
cellular amine metabolic process GO:0044106 44 0.270
cardiac muscle cell development GO:0055013 39 0.264
aorta morphogenesis GO:0035909 22 0.264
multicellular organismal homeostasis GO:0048871 164 0.261
inorganic ion transmembrane transport GO:0098660 234 0.260
epithelial tube morphogenesis GO:0060562 303 0.259
osteoclast differentiation GO:0030316 62 0.257
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.252
cell proliferation in hindbrain GO:0021534 10 0.249
cellular response to organonitrogen compound GO:0071417 145 0.248
sensory perception GO:0007600 245 0.247
Mouse
muscle tissue development GO:0060537 308 0.245
positive regulation of ossification GO:0045778 47 0.244
small molecule biosynthetic process GO:0044283 132 0.244
membrane organization GO:0061024 245 0.244
developmental maturation GO:0021700 193 0.237
brain derived neurotrophic factor receptor signaling pathway GO:0031547 3 0.235
asymmetric neuroblast division GO:0055059 1 0.235
jnk cascade GO:0007254 72 0.234
cellular response to carbohydrate stimulus GO:0071322 50 0.233
proteoglycan metabolic process GO:0006029 38 0.231
circulatory system process GO:0003013 197 0.230
ameboidal type cell migration GO:0001667 128 0.230
angiogenesis GO:0001525 201 0.229
bone development GO:0060348 120 0.228
sodium ion transport GO:0006814 73 0.228
morphogenesis of a branching structure GO:0001763 203 0.223
negative regulation of growth GO:0045926 99 0.222
branching morphogenesis of an epithelial tube GO:0048754 159 0.221
nucleotide metabolic process GO:0009117 332 0.221
regulation of ion transmembrane transporter activity GO:0032412 54 0.217
lung epithelium development GO:0060428 37 0.217
osteoblast development GO:0002076 17 0.216
formation of radial glial scaffolds GO:0021943 4 0.214
axial mesodermal cell fate commitment GO:0048322 1 0.214
response to amino acid GO:0043200 37 0.213
cellular trivalent inorganic anion homeostasis GO:0072502 2 0.213
positive regulation of growth GO:0045927 104 0.209
regulation of muscle tissue development GO:1901861 97 0.209
transmembrane transport GO:0055085 412 0.208
blood circulation GO:0008015 195 0.208
alcohol metabolic process GO:0006066 116 0.206
diencephalon development GO:0021536 63 0.205
mammary placode formation GO:0060596 4 0.204
stress activated mapk cascade GO:0051403 80 0.203
defense response to other organism GO:0098542 197 0.202
neuron projection guidance GO:0097485 141 0.201
enamel mineralization GO:0070166 7 0.200
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.199
cellular response to extracellular stimulus GO:0031668 81 0.197
rho protein signal transduction GO:0007266 32 0.190
regulation of cell projection organization GO:0031344 206 0.190
morphogenesis of a branching epithelium GO:0061138 193 0.190
synaptic transmission GO:0007268 329 0.189
epithelial cell proliferation GO:0050673 174 0.188
nucleoside metabolic process GO:0009116 246 0.187
bone morphogenesis GO:0060349 78 0.186
tooth mineralization GO:0034505 9 0.185
regulation of cell substrate adhesion GO:0010810 73 0.181
mammary gland epithelium development GO:0061180 65 0.178
renal system development GO:0072001 225 0.177
sensory perception of sound GO:0007605 97 0.174
regulation of positive chemotaxis GO:0050926 7 0.173
neuroblast division GO:0055057 10 0.172
cardiac muscle tissue development GO:0048738 130 0.171
regulation of osteoblast differentiation GO:0045667 67 0.171
positive regulation of protein modification process GO:0031401 299 0.170
mammary gland morphogenesis GO:0060443 54 0.170
divalent inorganic cation homeostasis GO:0072507 138 0.170
face development GO:0060324 38 0.168
embryonic genitalia morphogenesis GO:0030538 4 0.167
regulation of cellular amine metabolic process GO:0033238 20 0.166
appendage morphogenesis GO:0035107 149 0.166
regulation of rho protein signal transduction GO:0035023 71 0.164
response to nutrient levels GO:0031667 109 0.162
embryonic skeletal system morphogenesis GO:0048704 91 0.162
nucleobase containing small molecule metabolic process GO:0055086 352 0.162
brown fat cell differentiation GO:0050873 36 0.160
mapk cascade GO:0000165 281 0.160
establishment or maintenance of neuroblast polarity GO:0045196 1 0.160
positive regulation of epithelial cell proliferation GO:0050679 68 0.159
pallium development GO:0021543 120 0.157
regulation of ossification GO:0030278 112 0.157
regulation of aldosterone metabolic process GO:0032344 1 0.156
muscle cell differentiation GO:0042692 261 0.155
telencephalon development GO:0021537 186 0.155
cell type specific apoptotic process GO:0097285 268 0.155
placenta development GO:0001890 140 0.154
response to organonitrogen compound GO:0010243 246 0.153
forebrain ventricular zone progenitor cell division GO:0021869 6 0.152
tissue remodeling GO:0048771 102 0.152
camera type eye development GO:0043010 266 0.151
synapse assembly GO:0007416 56 0.151
regulation of heart growth GO:0060420 31 0.150
purine containing compound metabolic process GO:0072521 311 0.149
ventricular zone neuroblast division GO:0021847 3 0.148
actin cytoskeleton organization GO:0030036 220 0.147
peptide hormone secretion GO:0030072 109 0.146
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.146
peptide transport GO:0015833 133 0.145
organic anion transport GO:0015711 137 0.144
regulation of body fluid levels GO:0050878 162 0.144
blastocyst formation GO:0001825 33 0.144
myeloid cell differentiation GO:0030099 233 0.143
forebrain generation of neurons GO:0021872 63 0.141
positive regulation of fat cell differentiation GO:0045600 32 0.141
prostate gland morphogenesis GO:0060512 32 0.140
prenylation GO:0097354 3 0.139
extracellular matrix cell signaling GO:0035426 5 0.139
establishment of neuroblast polarity GO:0045200 1 0.139
regulation of fat cell differentiation GO:0045598 81 0.139
regulation of lipid metabolic process GO:0019216 118 0.139
cardiac muscle tissue morphogenesis GO:0055008 44 0.139
response to retinoic acid GO:0032526 56 0.139
embryonic skeletal joint development GO:0072498 13 0.137
kidney epithelium development GO:0072073 121 0.137
ras protein signal transduction GO:0007265 77 0.136
cytokine production GO:0001816 319 0.136
regulation of cell cycle GO:0051726 281 0.135
regulation of peptide secretion GO:0002791 77 0.133
mesenchyme development GO:0060485 152 0.133
regulation of cardiac muscle tissue development GO:0055024 31 0.133
apoptotic process involved in development GO:1902742 28 0.131
anatomical structure homeostasis GO:0060249 145 0.130
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.130
cell matrix adhesion GO:0007160 68 0.130
carbohydrate derivative biosynthetic process GO:1901137 183 0.129
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.129
negative regulation of cell motility GO:2000146 61 0.129
regulation of cellular ketone metabolic process GO:0010565 66 0.129
digestive tract development GO:0048565 190 0.129
neuronal action potential GO:0019228 54 0.128
regulation of cellular amino acid metabolic process GO:0006521 5 0.128
organonitrogen compound biosynthetic process GO:1901566 192 0.128
regulation of protein geranylgeranylation GO:2000539 2 0.128
regulation of lymphocyte activation GO:0051249 240 0.127
bone resorption GO:0045453 38 0.127
positive regulation of endothelial cell proliferation GO:0001938 17 0.127
regulation of nucleotide metabolic process GO:0006140 169 0.126
endothelial cell differentiation GO:0045446 41 0.126
branching involved in salivary gland morphogenesis GO:0060445 26 0.126
positive regulation of stem cell proliferation GO:2000648 59 0.125
protein catabolic process GO:0030163 221 0.124
oligodendrocyte differentiation GO:0048709 53 0.123
purine nucleotide metabolic process GO:0006163 302 0.122
regulation of purine nucleotide catabolic process GO:0033121 122 0.121
blood vessel morphogenesis GO:0048514 285 0.121
cellular carbohydrate metabolic process GO:0044262 119 0.121
morphogenesis of an epithelial bud GO:0060572 18 0.120
renal vesicle induction GO:0072034 3 0.120
purine nucleoside catabolic process GO:0006152 205 0.119
mammary gland bud formation GO:0060615 2 0.119
endocytosis GO:0006897 168 0.118
cation transport GO:0006812 399 0.118
negative regulation of stem cell maintenance GO:1902455 4 0.118
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.118
regulation of steroid biosynthetic process GO:0050810 26 0.118
glial cell development GO:0021782 54 0.117
ear morphogenesis GO:0042471 118 0.117
purine ribonucleoside catabolic process GO:0046130 205 0.117
ion transmembrane transport GO:0034220 361 0.115
nucleoside triphosphate metabolic process GO:0009141 230 0.115
purine nucleoside triphosphate metabolic process GO:0009144 226 0.114
striated muscle cell development GO:0055002 125 0.113
keratinocyte migration GO:0051546 3 0.111
immune effector process GO:0002252 321 0.111
positive regulation of protein kinase activity GO:0045860 144 0.110
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.110
regulation of organ morphogenesis GO:2000027 144 0.110
regulation of peptide transport GO:0090087 91 0.110
mesenchymal cell differentiation GO:0048762 107 0.109
metanephric loop of henle development GO:0072236 4 0.109
trachea cartilage morphogenesis GO:0060535 4 0.108
epithelial cell migration GO:0010631 63 0.107
regulation of membrane potential GO:0042391 192 0.107
response to vitamin d GO:0033280 3 0.107
renal sodium ion transport GO:0003096 2 0.106
forebrain cell migration GO:0021885 58 0.106
regulation of protein transport GO:0051223 163 0.106
calcium mediated signaling GO:0019722 46 0.105
positive regulation of neuron projection regeneration GO:0070572 2 0.104
cell substrate adhesion GO:0031589 130 0.103
carboxylic acid transport GO:0046942 100 0.103
canonical wnt signaling pathway GO:0060070 130 0.101
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.101
cell proliferation in external granule layer GO:0021924 10 0.101
locomotory behavior GO:0007626 195 0.100
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.100
regulation of chemotaxis GO:0050920 53 0.100
purine ribonucleotide metabolic process GO:0009150 290 0.099
regulation of angiogenesis GO:0045765 81 0.098
purine ribonucleotide biosynthetic process GO:0009152 59 0.098
positive regulation of tendon cell differentiation GO:2001051 1 0.098
cardiac muscle tissue growth GO:0055017 37 0.098
tissue homeostasis GO:0001894 115 0.098
trachea formation GO:0060440 3 0.097
salivary gland morphogenesis GO:0007435 33 0.096
regulation of ion transmembrane transport GO:0034765 119 0.096
regulation of embryonic development GO:0045995 71 0.095
regulation of lipid biosynthetic process GO:0046890 54 0.095
positive regulation of osteoblast differentiation GO:0045669 34 0.095
axonogenesis GO:0007409 274 0.095
regulation of astrocyte differentiation GO:0048710 20 0.095
regulation of stem cell differentiation GO:2000736 50 0.095
insulin secretion GO:0030073 89 0.094
cellular metal ion homeostasis GO:0006875 151 0.094
heterocycle catabolic process GO:0046700 280 0.094
carbohydrate derivative catabolic process GO:1901136 231 0.094
regulation of metal ion transport GO:0010959 106 0.094
regulation of neuron apoptotic process GO:0043523 122 0.094
cellular response to cytokine stimulus GO:0071345 189 0.093
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.093
glutamate metabolic process GO:0006536 9 0.092
endoderm development GO:0007492 45 0.092
regulation of epithelial cell proliferation GO:0050678 141 0.092
regulation of cell adhesion GO:0030155 154 0.092
gland development GO:0048732 330 0.091
regulation of cellular response to stress GO:0080135 159 0.091
response to ischemia GO:0002931 14 0.091
regulation of kinase activity GO:0043549 249 0.091
engulfment of apoptotic cell GO:0043652 3 0.090
c21 steroid hormone metabolic process GO:0008207 7 0.090
oligodendrocyte development GO:0014003 20 0.090
regulation of protein localization GO:0032880 231 0.089
cytoplasmic transport GO:0016482 234 0.089
prostate gland morphogenetic growth GO:0060737 4 0.088
ribonucleotide metabolic process GO:0009259 291 0.088
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.088
inner ear morphogenesis GO:0042472 101 0.087
organic cyclic compound catabolic process GO:1901361 295 0.087
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.087
protein geranylgeranylation GO:0018344 3 0.086
neural precursor cell proliferation GO:0061351 121 0.086
wound healing GO:0042060 157 0.086
long term synaptic potentiation GO:0060291 25 0.086
odontogenesis of dentin containing tooth GO:0042475 66 0.086
roof plate formation GO:0021509 1 0.085
limb development GO:0060173 166 0.085
regulation of peptide hormone secretion GO:0090276 75 0.085
extrinsic apoptotic signaling pathway GO:0097191 126 0.085
receptor mediated endocytosis GO:0006898 51 0.085
regulation of rac gtpase activity GO:0032314 13 0.085
purine ribonucleoside metabolic process GO:0046128 241 0.084
monovalent inorganic anion homeostasis GO:0055083 6 0.084
cellular response to monosaccharide stimulus GO:0071326 47 0.084
wnt signaling pathway GO:0016055 188 0.084
learning or memory GO:0007611 148 0.084
neural crest cell differentiation GO:0014033 54 0.083
response to extracellular stimulus GO:0009991 127 0.083
alcohol biosynthetic process GO:0046165 43 0.083
ribonucleoside catabolic process GO:0042454 206 0.083
cellular response to abiotic stimulus GO:0071214 56 0.083
nephrogenic mesenchyme development GO:0072076 3 0.082
positive regulation of wnt signaling pathway GO:0030177 45 0.082
negative regulation of intracellular signal transduction GO:1902532 167 0.082
endodermal cell fate determination GO:0007493 2 0.082
positive regulation of bone mineralization GO:0030501 12 0.082
myelination in peripheral nervous system GO:0022011 19 0.082
specification of organ position GO:0010159 3 0.082
positive regulation of cell motility GO:2000147 116 0.082
organophosphate catabolic process GO:0046434 232 0.082
regulation of neuron death GO:1901214 134 0.081
metanephros development GO:0001656 79 0.080
nucleotide catabolic process GO:0009166 217 0.080
regulation of establishment of protein localization GO:0070201 181 0.080
regulation of mesenchymal cell proliferation GO:0010464 37 0.080
protein targeting GO:0006605 143 0.080
negative regulation of nervous system development GO:0051961 156 0.080
glucose homeostasis GO:0042593 128 0.078
mammary gland duct morphogenesis GO:0060603 38 0.078
developmental growth involved in morphogenesis GO:0060560 138 0.078
plasma membrane organization GO:0007009 90 0.077
cgmp metabolic process GO:0046068 20 0.076
positive regulation of secretion by cell GO:1903532 114 0.076
cell division GO:0051301 120 0.075
nucleoside phosphate biosynthetic process GO:1901293 79 0.075
molting cycle GO:0042303 90 0.075
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.075
regulation of stem cell proliferation GO:0072091 78 0.075
mesenchymal cell development GO:0014031 93 0.074
camp mediated signaling GO:0019933 15 0.074
regulation of t cell proliferation GO:0042129 92 0.073
cardiac ventricle development GO:0003231 83 0.073
response to testosterone GO:0033574 3 0.073
organ growth GO:0035265 117 0.073
divalent inorganic cation transport GO:0072511 178 0.073
mesoderm development GO:0007498 100 0.073
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.073
trophectodermal cellular morphogenesis GO:0001831 3 0.072
regulation of system process GO:0044057 200 0.072
positive regulation of protein phosphorylation GO:0001934 242 0.072
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.072
regulation of cardiac muscle tissue growth GO:0055021 26 0.072
cardiac right atrium morphogenesis GO:0003213 3 0.072
cellular response to acid chemical GO:0071229 68 0.071
purine nucleotide catabolic process GO:0006195 211 0.071
regulation of chondrocyte differentiation GO:0032330 33 0.071
cellular response to lipid GO:0071396 145 0.071
metanephric nephron tubule development GO:0072234 16 0.071
regulation of cell size GO:0008361 72 0.071
apoptotic process involved in morphogenesis GO:0060561 25 0.070
mechanoreceptor differentiation GO:0042490 67 0.070
b cell activation GO:0042113 161 0.070
negative regulation of apoptotic signaling pathway GO:2001234 104 0.070
cellular response to vitamin GO:0071295 2 0.070
heart morphogenesis GO:0003007 178 0.070
regulation of canonical wnt signaling pathway GO:0060828 82 0.070
regulation of cytoskeleton organization GO:0051493 122 0.070
positive regulation of secretion GO:0051047 130 0.070
potassium ion homeostasis GO:0055075 4 0.070
adaptive immune response GO:0002250 155 0.069
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.069
purine containing compound catabolic process GO:0072523 213 0.068
calcium ion transport GO:0006816 159 0.068
steroid biosynthetic process GO:0006694 47 0.068
regulation of cellular component biogenesis GO:0044087 181 0.068
purine containing compound biosynthetic process GO:0072522 70 0.068
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.067
regulation of hydrolase activity GO:0051336 246 0.067
organic acid transport GO:0015849 101 0.067
multicellular organismal signaling GO:0035637 91 0.067
maternal process involved in female pregnancy GO:0060135 32 0.067
regulation of muscle adaptation GO:0043502 31 0.067
sensory perception of mechanical stimulus GO:0050954 107 0.067
biomineral tissue development GO:0031214 64 0.066
regulation of homeostatic process GO:0032844 182 0.066
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.066
transmission of nerve impulse GO:0019226 76 0.066
regulation of white fat cell proliferation GO:0070350 2 0.066
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.065
axon guidance GO:0007411 141 0.065
chondrocyte development GO:0002063 24 0.065
leukocyte chemotaxis GO:0030595 69 0.065
response to oxygen levels GO:0070482 62 0.065
regulation of timing of cell differentiation GO:0048505 11 0.065
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.064
negative regulation of prostatic bud formation GO:0060686 4 0.064
regulation of endothelial cell proliferation GO:0001936 23 0.064
glucose transport GO:0015758 56 0.064
cardiocyte differentiation GO:0035051 87 0.064
Mouse
lymphocyte mediated immunity GO:0002449 139 0.063
positive chemotaxis GO:0050918 18 0.063
regulation of cell motility GO:2000145 236 0.063
sensory perception of light stimulus GO:0050953 54 0.063
protein localization to organelle GO:0033365 185 0.063
somatic stem cell maintenance GO:0035019 47 0.063
regulation of protein kinase b signaling GO:0051896 56 0.062
regulation of phospholipase a2 activity GO:0032429 3 0.062
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.062
digestive tract morphogenesis GO:0048546 147 0.062
regulation of proteolysis GO:0030162 164 0.062
oocyte differentiation GO:0009994 35 0.061
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.061
asymmetric stem cell division GO:0098722 3 0.061
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.061
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.061
protein kinase b signaling GO:0043491 74 0.061
positive regulation of apoptotic signaling pathway GO:2001235 95 0.061
kidney mesenchyme morphogenesis GO:0072131 4 0.060
membrane invagination GO:0010324 17 0.060
purine nucleotide biosynthetic process GO:0006164 65 0.060
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.059
response to monosaccharide GO:0034284 67 0.059
regulation of smoothened signaling pathway GO:0008589 58 0.059
axon ensheathment GO:0008366 76 0.059
nucleoside triphosphate catabolic process GO:0009143 205 0.059
cardiac cell development GO:0055006 41 0.058
skeletal muscle fiber development GO:0048741 58 0.058
cognition GO:0050890 149 0.057
negative regulation of muscle hypertrophy GO:0014741 9 0.057
regulation of purine nucleotide metabolic process GO:1900542 169 0.057
cellular chemical homeostasis GO:0055082 215 0.057
positive regulation of heart growth GO:0060421 18 0.057
negative regulation of multi organism process GO:0043901 68 0.056
cellular response to organic cyclic compound GO:0071407 87 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.056
negative regulation of wnt signaling pathway GO:0030178 73 0.055
branch elongation involved in salivary gland morphogenesis GO:0060667 2 0.055
t cell differentiation in thymus GO:0033077 77 0.055
positive regulation of cell projection organization GO:0031346 95 0.055
nucleoside phosphate catabolic process GO:1901292 222 0.055
endodermal cell fate specification GO:0001714 4 0.055
axis elongation involved in somitogenesis GO:0090245 4 0.054
peptide secretion GO:0002790 114 0.054
regulation of mesenchymal cell apoptotic process GO:2001053 14 0.054
tissue migration GO:0090130 68 0.054
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.054
sterol transport GO:0015918 38 0.054
germ cell development GO:0007281 185 0.053
cyclic nucleotide biosynthetic process GO:0009190 44 0.053
cerebellar granule cell precursor proliferation GO:0021930 10 0.053
regulation of neural precursor cell proliferation GO:2000177 70 0.053
embryonic skeletal joint morphogenesis GO:0060272 11 0.053
positive regulation of kinase activity GO:0033674 155 0.053
toxin transport GO:1901998 38 0.053
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.053
regulation of map kinase activity GO:0043405 120 0.052
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.052
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.052
replacement ossification GO:0036075 26 0.052
regulation of nucleoside metabolic process GO:0009118 130 0.052
insulin like growth factor receptor signaling pathway GO:0048009 21 0.052

Phex disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.956
disease of anatomical entity DOID:7 0 0.956
musculoskeletal system disease DOID:17 0 0.956
connective tissue disease DOID:65 0 0.956
bone remodeling disease DOID:0080005 0 0.630
nervous system disease DOID:863 0 0.464
sensory system disease DOID:0050155 0 0.406
bone development disease DOID:0080006 0 0.350
osteochondrodysplasia DOID:2256 0 0.282
central nervous system disease DOID:331 0 0.081
cancer DOID:162 0 0.072
disease of cellular proliferation DOID:14566 0 0.072
organ system cancer DOID:0050686 0 0.057