Mus musculus

7 known processes

Phf21a

PHD finger protein 21A

(Aliases: MGC123676,Bhc,80kDa,PFTF1,Bhc80,D030065N23Rik,MGC29190)

Phf21a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene silencing by mirna GO:0035195 10 0.577
histone methylation GO:0016571 71 0.506
chromatin organization GO:0006325 206 0.419
histone lysine methylation GO:0034968 50 0.310
chromatin modification GO:0016568 187 0.232
protein methylation GO:0006479 81 0.229
peptidyl lysine modification GO:0018205 77 0.210
histone modification GO:0016570 159 0.125
aromatic compound catabolic process GO:0019439 286 0.112
histone acetylation GO:0016573 41 0.108
methylation GO:0032259 134 0.097
covalent chromatin modification GO:0016569 163 0.093
posttranscriptional regulation of gene expression GO:0010608 155 0.089
digestive tract development GO:0048565 190 0.075
cellular ketone metabolic process GO:0042180 84 0.073
cellular macromolecule catabolic process GO:0044265 206 0.072
dna metabolic process GO:0006259 303 0.070
digestive system development GO:0055123 200 0.070
macromolecule methylation GO:0043414 120 0.069
leukocyte differentiation GO:0002521 342 0.063
amine metabolic process GO:0009308 45 0.061
regulation of cellular ketone metabolic process GO:0010565 66 0.058
embryonic hemopoiesis GO:0035162 23 0.057
macromolecule catabolic process GO:0009057 281 0.056
rna processing GO:0006396 105 0.055
t cell activation GO:0042110 289 0.055
cytokine production GO:0001816 319 0.055
gene silencing by rna GO:0031047 19 0.055
digestive tract morphogenesis GO:0048546 147 0.053
regulation of defense response GO:0031347 233 0.053
mrna metabolic process GO:0016071 84 0.052
gene silencing GO:0016458 38 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
posttranscriptional gene silencing GO:0016441 10 0.052
organic cyclic compound catabolic process GO:1901361 295 0.051
peptidyl lysine methylation GO:0018022 29 0.051
peptidyl amino acid modification GO:0018193 336 0.050
ras protein signal transduction GO:0007265 77 0.049
posttranscriptional gene silencing by rna GO:0035194 10 0.049
striated muscle tissue development GO:0014706 293 0.049
cellular amino acid metabolic process GO:0006520 103 0.048
glucose metabolic process GO:0006006 92 0.046
regionalization GO:0003002 337 0.044
negative regulation of cellular protein metabolic process GO:0032269 247 0.044
histone h3 k4 trimethylation GO:0080182 5 0.044
cellular nitrogen compound catabolic process GO:0044270 280 0.044
negative regulation of molecular function GO:0044092 258 0.042
establishment or maintenance of cell polarity GO:0007163 86 0.042
renal system development GO:0072001 225 0.040
small gtpase mediated signal transduction GO:0007264 97 0.040
heterocycle catabolic process GO:0046700 280 0.040
dna alkylation GO:0006305 43 0.039
negative regulation of cell proliferation GO:0008285 296 0.039
negative regulation of protein metabolic process GO:0051248 282 0.037
gtp metabolic process GO:0046039 144 0.036
internal protein amino acid acetylation GO:0006475 42 0.036
cellular response to dna damage stimulus GO:0006974 207 0.036
homeostasis of number of cells GO:0048872 210 0.036
carbohydrate metabolic process GO:0005975 230 0.036
negative regulation of immune system process GO:0002683 209 0.036
urogenital system development GO:0001655 261 0.035
protein acylation GO:0043543 64 0.035
cellular amine metabolic process GO:0044106 44 0.035
muscle tissue development GO:0060537 308 0.035
gastrulation GO:0007369 116 0.035
histone h3 k4 methylation GO:0051568 23 0.034
purine ribonucleotide catabolic process GO:0009154 208 0.033
skeletal system development GO:0001501 356 0.033
internal peptidyl lysine acetylation GO:0018393 42 0.033
protein modification by small protein conjugation or removal GO:0070647 207 0.033
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.032
protein catabolic process GO:0030163 221 0.032
stem cell differentiation GO:0048863 268 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
peptidyl lysine acetylation GO:0018394 45 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
protein alkylation GO:0008213 81 0.030
purine containing compound metabolic process GO:0072521 311 0.030
regulation of cytokine production GO:0001817 266 0.030
ossification GO:0001503 216 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.029
dna modification GO:0006304 50 0.029
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
glucose homeostasis GO:0042593 128 0.027
t cell differentiation GO:0030217 174 0.027
rna splicing GO:0008380 54 0.027
regulation of neuron differentiation GO:0045664 281 0.026
nucleotide catabolic process GO:0009166 217 0.026
kidney development GO:0001822 213 0.026
positive regulation of dna templated transcription elongation GO:0032786 2 0.026
stem cell maintenance GO:0019827 130 0.025
positive regulation of t cell anergy GO:0002669 4 0.025
protein targeting GO:0006605 143 0.025
endoderm formation GO:0001706 20 0.024
oxidation reduction process GO:0055114 342 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
regulation of organ morphogenesis GO:2000027 144 0.023
epithalamus development GO:0021538 2 0.022
endoderm development GO:0007492 45 0.022
carbohydrate homeostasis GO:0033500 128 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
compound eye development GO:0048749 1 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
stem cell fate specification GO:0048866 3 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.021
regulation of mitotic cell cycle GO:0007346 126 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
male gamete generation GO:0048232 285 0.021
skeletal muscle organ development GO:0060538 163 0.021
monosaccharide metabolic process GO:0005996 106 0.020
regulation of lymphocyte anergy GO:0002911 4 0.020
muscle cell differentiation GO:0042692 261 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
lymphocyte differentiation GO:0030098 242 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
regulation of histone methylation GO:0031060 30 0.020
regulation of mrna processing GO:0050684 41 0.020
regulation of cell activation GO:0050865 289 0.020
hexose metabolic process GO:0019318 98 0.020
positive regulation of nervous system development GO:0051962 221 0.019
regulation of t cell activation GO:0050863 170 0.019
epithelial cell proliferation GO:0050673 174 0.019
t cell proliferation GO:0042098 120 0.019
histone h4 k16 acetylation GO:0043984 3 0.019
regulation of chromosome organization GO:0033044 83 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
regulation of inflammatory response GO:0050727 147 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
retrograde transport endosome to golgi GO:0042147 2 0.018
immune effector process GO:0002252 321 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
cellular response to lipid GO:0071396 145 0.018
negative regulation of protein modification process GO:0031400 163 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
nucleoside catabolic process GO:0009164 206 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.018
cell type specific apoptotic process GO:0097285 268 0.017
rna catabolic process GO:0006401 29 0.017
transcription from rna polymerase iii promoter GO:0006383 3 0.017
organic hydroxy compound transport GO:0015850 93 0.017
mrna processing GO:0006397 63 0.017
cellular response to starvation GO:0009267 57 0.017
regulation of histone modification GO:0031056 56 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
norepinephrine transport GO:0015874 2 0.017
apoptotic signaling pathway GO:0097190 306 0.017
cellular response to nutrient levels GO:0031669 64 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
alpha beta t cell activation GO:0046631 91 0.017
alpha beta t cell differentiation GO:0046632 69 0.017
purine containing compound catabolic process GO:0072523 213 0.016
regulation of cell migration GO:0030334 219 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
cellular response to external stimulus GO:0071496 88 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
germ cell development GO:0007281 185 0.016
regulation of mrna metabolic process GO:1903311 43 0.016
defense response to other organism GO:0098542 197 0.016
regulation of response to wounding GO:1903034 189 0.016
appendage morphogenesis GO:0035107 149 0.016
habenula development GO:0021986 2 0.016
gonad development GO:0008406 141 0.016
mesenchyme development GO:0060485 152 0.016
regulation of chromatin organization GO:1902275 57 0.016
regulation of interleukin 6 production GO:0032675 55 0.016
placenta development GO:0001890 140 0.016
negative regulation of inflammatory response GO:0050728 61 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
heterochromatin organization GO:0070828 4 0.016
interleukin 6 production GO:0032635 58 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
protein localization to organelle GO:0033365 185 0.015
somatic stem cell maintenance GO:0035019 47 0.015
regulation of t cell proliferation GO:0042129 92 0.015
nucleotide metabolic process GO:0009117 332 0.015
negative regulation of cell development GO:0010721 169 0.015
gland development GO:0048732 330 0.015
myeloid cell homeostasis GO:0002262 114 0.015
regulation of hormone levels GO:0010817 211 0.015
myeloid cell differentiation GO:0030099 233 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
negative regulation of defense response GO:0031348 77 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
cellular response to extracellular stimulus GO:0031668 81 0.015
regulation of leukocyte proliferation GO:0070663 121 0.014
tube formation GO:0035148 140 0.014
regulation of homeostatic process GO:0032844 182 0.014
negative regulation of cell activation GO:0050866 111 0.014
embryonic placenta development GO:0001892 98 0.014
nucleoside metabolic process GO:0009116 246 0.014
endocytosis GO:0006897 168 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
rho protein signal transduction GO:0007266 32 0.014
erythrocyte differentiation GO:0030218 88 0.014
negative regulation of t cell activation GO:0050868 65 0.014
stem cell development GO:0048864 219 0.014
positive regulation of protein modification process GO:0031401 299 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
positive regulation of cytokine production GO:0001819 174 0.014
cardiocyte differentiation GO:0035051 87 0.014
rac protein signal transduction GO:0016601 13 0.014
regulation of blood pressure GO:0008217 93 0.014
leukocyte proliferation GO:0070661 172 0.014
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.014
oogenesis GO:0048477 56 0.014
skeletal system morphogenesis GO:0048705 203 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
appendage development GO:0048736 166 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
carbohydrate biosynthetic process GO:0016051 74 0.013
learning or memory GO:0007611 148 0.013
regulation of protein sumoylation GO:0033233 4 0.013
epithelial tube formation GO:0072175 130 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
myotube differentiation GO:0014902 105 0.013
exocytosis GO:0006887 121 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
limb development GO:0060173 166 0.013
camera type eye development GO:0043010 266 0.013
negative regulation of immune effector process GO:0002698 55 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
neural tube development GO:0021915 160 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
regulation of asymmetric cell division GO:0009786 4 0.012
regulation of organelle organization GO:0033043 289 0.012
artery development GO:0060840 53 0.012
cellular protein catabolic process GO:0044257 155 0.012
demethylation GO:0070988 23 0.012
histone deubiquitination GO:0016578 2 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
regulation of mapk cascade GO:0043408 248 0.012
forebrain development GO:0030900 302 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
positive regulation of chromosome organization GO:2001252 33 0.012
regulation of anatomical structure size GO:0090066 178 0.012
chemotaxis GO:0006935 247 0.012
response to acid chemical GO:0001101 111 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
neural precursor cell proliferation GO:0061351 121 0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.012
muscle cell development GO:0055001 133 0.012
regulation of t cell anergy GO:0002667 4 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
regulation of protein localization GO:0032880 231 0.012
negative regulation of organelle organization GO:0010639 90 0.012
regulation of protein catabolic process GO:0042176 108 0.012
neuroblast differentiation GO:0014016 2 0.012
pharynx development GO:0060465 1 0.012
purine nucleotide catabolic process GO:0006195 211 0.011
axon guidance GO:0007411 141 0.011
blood vessel morphogenesis GO:0048514 285 0.011
regulation of rna splicing GO:0043484 37 0.011
regulation of cellular response to stress GO:0080135 159 0.011
adult behavior GO:0030534 135 0.011
t cell anergy GO:0002870 4 0.011
mirna catabolic process GO:0010587 2 0.011
lung development GO:0030324 164 0.011
monosaccharide biosynthetic process GO:0046364 44 0.011
catecholamine secretion GO:0050432 15 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
protein ubiquitination GO:0016567 171 0.011
regulation of multi organism process GO:0043900 111 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
negative regulation of response to wounding GO:1903035 77 0.011
mitotic cell cycle GO:0000278 195 0.011
regulation of chromatin modification GO:1903308 57 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
development of primary sexual characteristics GO:0045137 143 0.011
respiratory tube development GO:0030323 167 0.011
positive regulation of organelle organization GO:0010638 128 0.011
negative regulation of t cell proliferation GO:0042130 38 0.011
endocrine system development GO:0035270 98 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
organelle localization GO:0051640 179 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
synaptic transmission GO:0007268 329 0.011
lymphocyte anergy GO:0002249 4 0.011
nephron epithelium development GO:0072009 92 0.011
chromatin remodeling GO:0006338 32 0.011
histone h4 k20 methylation GO:0034770 8 0.011
regulation of secretion GO:0051046 274 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
nuclear transcribed mrna poly a tail shortening GO:0000289 7 0.011
formation of primary germ layer GO:0001704 77 0.010
response to oxygen radical GO:0000305 16 0.010
mesoderm development GO:0007498 100 0.010
regulation of alpha beta t cell activation GO:0046634 53 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
blood circulation GO:0008015 195 0.010
somatic diversification of immunoglobulins GO:0016445 43 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
lateral inhibition GO:0046331 1 0.010
cell fate commitment GO:0045165 210 0.010
sensory perception GO:0007600 245 0.010
cellular homeostasis GO:0019725 240 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
negative regulation of lymphocyte proliferation GO:0050672 45 0.010
negative regulation of cytokine production GO:0001818 84 0.010
cell fate specification GO:0001708 72 0.010
neuroblast fate commitment GO:0014017 1 0.010
organelle assembly GO:0070925 177 0.010
establishment of organelle localization GO:0051656 122 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
limb morphogenesis GO:0035108 149 0.010
negative regulation of histone modification GO:0031057 18 0.010

Phf21a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010